| Sunday, January 9 |
| Former Astro Johnny Temple dies in Anderson, SC at the age of 67. |
| Monday, April 4 |
| » Defeated Expos (0-1), 6-5 | Astrodome (1-0) | 1-0 | |
| » W: Tom Edens (1-0) L: Jeff Shaw (0-1) | First | -- |
| » Major-league debuts: James Mouton and Roberto Petagine (Astros) |
| Tuesday, April 5 |
| » Lost to Expos (1-1), 5-1 | Astrodome (1-1) | 1-1 | |
| » W: Ken Hill (1-0) L: Doug Drabek (0-1) | First | -- |
| Wednesday, April 6 |
| » Lost to Expos (2-1), 9-3 | Astrodome (1-2) | 1-2 | Lost 2 |
| » W: Kirk Rueter (1-0) L: Darryl Kile (0-1) | Second | ½ out |
| Friday, April 8 |
| » Defeated Mets (3-1), 6-3 | Astrodome (2-2) | 2-2 | |
| » W: Greg Swindell (1-0) L: Eric Hillman (0-1) S: Mitch Williams (1) | Third | ½ out |
| Saturday, April 9 |
| » Lost to Mets (4-1), 8-2 | Astrodome (2-3) | 2-3 | |
| » W: Bret Saberhagen (1-0) L: Pete Harnisch (0-1) | Third | 1½ out |
| Sunday, April 10 |
| » Defeated Mets (4-2), 6-1 | Astrodome (3-3) | 3-3 | |
| » W: Doug Drabek (1-1) L: Pete Smith (1-1) | Third | 1½ out |
| Tuesday, April 12 |
| » Defeated Marlins (3-4), 7-2 | Joe Robbie Stadium (1-0) | 4-3 | Won 2 |
| » W: Darryl Kile (1-1) L: Ryan Bowen (0-2) S: Tom Edens (1) | Second | 2 out |
| Wednesday, April 13 |
| » Defeated Marlins (3-5), 4-2 | Joe Robbie Stadium (2-0) | 5-3 | Won 3 |
| » W: Greg Swindell (2-0) L: Chris Hammond (1-1) | Second | 1 out |
| Thursday, April 14 |
| » Lost to Marlins (4-5), 8-2 | Joe Robbie Stadium (2-1) | 5-4 | |
| » W: Dave Weathers (1-1) L: Pete Harnisch (0-2) | Third | 1½ out |
| Friday, April 15 |
| » Defeated Mets (5-4), 8-1 | Shea Stadium (1-0) | 6-4 | |
| » W: Doug Drabek (2-1) L: Pete Smith (1-2) | Second | ½ out |
| Saturday, April 16 |
| » Lost to Mets (6-4), 9-1 | Shea Stadium (1-1) | 6-5 | |
| » W: Dwight Gooden (2-0) L: Brian Williams (0-1) S: Mike Maddux (2) | Second | ½ out |
| Sunday, April 17 |
| » Lost to Mets (7-4), 4-2 | Shea Stadium (1-2) | 6-6 | Lost 2 |
| » W: Bobby Jones (2-1) L: Todd Jones (0-1) S: John Franco (2) | Third | 1½ out |
| Tuesday, April 19 |
| » Defeated Cubs (3-9), 3-0 | Wrigley Field (1-0) | 7-6 | |
| » W: Greg Swindell (3-0) L: Steve Trachsel (1-1) S: Mitch Williams (2) | Third | 1½ out |
| Wednesday, April 20 |
| » Defeated Cubs (3-10), 7-5 | Wrigley Field (2-0) | 8-6 | Won 2 |
| » W: Tom Edens (2-0) L: Jose Bautista (0-1) S: Mitch Williams (3) | Third | 1½ out |
| Friday, April 22 |
| » Lost to Cardinals (10-5), 6-5 | Busch Stadium II (0-1) | 8-7 | |
| » W: Rob Murphy (1-1) L: Mitch Williams (0-1) | Third | 2½ out |
| Saturday, April 23 |
| » Defeated Cardinals (10-6), 15-5 | Busch Stadium II (1-1) | 9-7 | |
| » W: Darryl Kile (2-1) L: Rene Arocha (1-2) | Third | 1½ out |
| » Major-league debuts: John Mabry (Cardinals) John Hudek (Astros) |
| Sunday, April 24 |
| » Lost to Cardinals (11-6), 5-4 | Busch Stadium II (1-2) | 9-8 | |
| » W: Rich Rodriguez (1-0) L: Tom Edens (2-1) S: Mike Perez (6) | Third | 2½ out |
| Monday, April 25 |
| » Defeated Pirates (8-9), 7-3 | Astrodome (4-3) | 10-8 | |
| » W: Pete Harnisch (1-2) L: Denny Neagle (1-3) | Third | 2½ out |
| Tuesday, April 26 |
| » Lost to Pirates (9-9), 7-4 | Astrodome (4-4) | 10-9 | |
| » W: Mark Dewey (2-0) L: Todd Jones (0-2) S: Rick White (4) | Third | 3½ out |
| Wednesday, April 27 |
| » Defeated Cubs (5-14), 8-5 | Astrodome (5-4) | 11-9 | |
| » W: Shane Reynolds (1-0) L: Jose Bautista (0-2) | Third | 2½ out |
| Thursday, April 28 |
| » Lost to Cubs (6-14), 5-3 | Astrodome (5-5) | 11-10 | |
| » W: Chuck Crim (1-0) L: Mitch Williams (0-2) S: Randy Myers (3) | Third | 3½ out |
| Friday, April 29 |
| » Defeated Cardinals (12-8), 4-3 | Astrodome (6-5) | 12-10 | |
| » W: Mike Hampton (1-0) L: Rich Rodriguez (1-1) | Third | 3½ out |
| Saturday, April 30 |
| » Defeated Cardinals (12-9), 15-5 | Astrodome (7-5) | 13-10 | Won 2 |
| » W: Pete Harnisch (2-2) L: Allen Watson (2-1) | Third | 2½ out |
| » Major-league debuts: Frank Cimorelli and Bryan Eversgerd (Cardinals) |
| Sunday, May 1 |
| » Lost to Cardinals (13-9), 6-5 | Astrodome (7-6) | 13-11 | |
| » W: Bob Tewksbury (6-0) L: Mike Hampton (1-1) S: Rob Murphy (1) | Fourth | 2½ out |
| Monday, May 2 |
| » Major-league debuts: Ray Holbert (Padres) |
| Tuesday, May 3 |
| » Defeated Pirates (13-11), 7-4 | Three Rivers Stadium (1-0) | 14-11 | |
| » W: Doug Drabek (3-1) L: Zane Smith (3-2) S: Mitch Williams (4) | Third | 3 out |
| Wednesday, May 4 |
| » Defeated Pirates (13-12), 7-4 | Three Rivers Stadium (2-0) | 15-11 | Won 2 |
| » W: Darryl Kile (3-1) L: Randy Tomlin (0-2) | Third | 2 out |
| Thursday, May 5 |
| » Defeated Reds (17-10), 8-6 | Riverfront Stadium (1-0) | 16-11 | Won 3 |
| » W: Mitch Williams (1-2) L: Jeff Brantley (1-1) S: John Hudek (1) | Second | 1 out |
| Friday, May 6 |
| » Lost to Reds (18-10), 4-3 | Riverfront Stadium (1-1) | 16-12 | |
| » W: Tim Pugh (3-1) L: Pete Harnisch (2-3) S: Hector Carrasco (3) | Third | 2 out |
| Saturday, May 7 |
| » Lost to Reds (19-10), 11-7 | Riverfront Stadium (1-2) | 16-13 | Lost 2 |
| » W: John Smiley (4-2) L: Brian Williams (0-2) | Third | 3 out |
| Sunday, May 8 |
| » Defeated Reds (19-11), 5-0 | Riverfront Stadium (2-2) | 17-13 | |
| » W: Doug Drabek (4-1) L: Erik Hanson (2-2) | Second | 2 out |
| Monday, May 9 |
| » Lost to Dodgers (15-17), 9-8 | Dodger Stadium (0-1) | 17-14 | |
| » W: Al Osuna (1-0) L: Mitch Williams (1-3) | Third | 3 out |
| Tuesday, May 10 |
| » Lost to Dodgers (16-17), 5-4 | Dodger Stadium (0-2) | 17-15 | Lost 2 |
| » W: Jim Gott (4-1) L: Dave Veres (0-1) | Third | 4 out |
| » Major-league debuts: Dave Veres (Astros) |
| Wednesday, May 11 |
| » Lost to Dodgers (17-17), 1-0 | Dodger Stadium (0-3) | 17-16 | Lost 3 |
| » W: Pedro Astacio (2-3) L: Shane Reynolds (1-1) | Third | 5 out |
| Friday, May 13 |
| » Defeated Rockies (14-18), 4-2 | Astrodome (8-6) | 18-16 | |
| » W: Doug Drabek (5-1) L: Marvin Freeman (3-1) | Second | 4 out |
| Saturday, May 14 |
| » Lost to Rockies (15-18), 4-2 | Astrodome (8-7) | 18-17 | |
| » W: David Nied (5-2) L: Darryl Kile (3-2) S: Bruce Ruffin (2) | Third | 4 out |
| Sunday, May 15 |
| » Lost to Rockies (16-18), 4-0 | Astrodome (8-8) | 18-18 | Lost 2 |
| » W: Armando Reynoso (3-3) L: Greg Swindell (3-1) | Third | 5 out |
| Monday, May 16 |
| » Defeated Giants (20-18), 3-2 | Astrodome (9-8) | 19-18 | |
| » W: Dave Veres (1-1) L: Bryan Hickerson (2-2) S: Mitch Williams (5) | Second | 4½ out |
| Tuesday, May 17 |
| » Lost to Giants (21-18), 5-2 | Astrodome (9-9) | 19-19 | |
| » W: Bill Swift (6-3) L: Pete Harnisch (2-4) S: Rod Beck (7) | Third | 5½ out |
| Wednesday, May 18 |
| » Defeated Giants (21-19), 4-2 | Astrodome (10-9) | 20-19 | |
| » W: Doug Drabek (6-1) L: Mark Portugal (4-3) S: John Hudek (2) | Third | 4½ out |
| Thursday, May 19 |
| » Defeated Padres (10-30), 9-5 | Astrodome (11-9) | 21-19 | Won 2 |
| » W: Tom Edens (3-1) L: Jose Martinez (0-2) | Third | 4½ out |
| Friday, May 20 |
| » Defeated Padres (10-31), 2-1 | Astrodome (12-9) | 22-19 | Won 3 |
| » W: Greg Swindell (4-1) L: Andy Ashby (0-4) S: John Hudek (3) | Third | 4½ out |
| Saturday, May 21 |
| » Defeated Padres (10-32), 4-2 | Astrodome (13-9) | 23-19 | Won 4 |
| » W: Shane Reynolds (2-1) L: Andy Benes (2-8) S: Mitch Williams (6) | Third | 3½ out |
| Sunday, May 22 |
| » Lost to Padres (11-32), 7-6 | Astrodome (13-10) | 23-20 | |
| » W: Pedro Martinez (1-1) L: Mitch Williams (1-4) S: Trevor Hoffman (4) | Third | 3½ out |
| Tuesday, May 24 |
| » Defeated Braves (27-15), 8-0 | Atlanta-Fulton County Stadium (1-0) | 24-20 | |
| » W: Doug Drabek (7-1) L: Tom Glavine (5-4) | Second | 2 out |
| Wednesday, May 25 |
| » Lost to Braves (28-15), 6-5 | Atlanta-Fulton County Stadium (1-1) | 24-21 | |
| » W: Mike Bielecki (1-0) L: Dave Veres (1-2) | Third | 2 out |
| Thursday, May 26 |
| » Defeated Braves (28-16), 8-5 | Atlanta-Fulton County Stadium (2-1) | 25-21 | |
| » W: Greg Swindell (5-1) L: Mike Stanton (1-1) S: John Hudek (4) | Third | 2 out |
| Friday, May 27 |
| » Defeated Phillies (22-25), 4-2 | Veteran's Stadium (1-0) | 26-21 | Won 2 |
| » W: Shane Reynolds (3-1) L: Shawn Boskie (1-2) S: John Hudek (5) | Second | 1 out |
| » Major-league debuts: Toby Borland (Phillies) |
| Saturday, May 28 |
| » Defeated Phillies (22-26), 7-5 | Veteran's Stadium (2-0) | 27-21 | Won 3 |
| » W: Brian Williams (1-2) L: Andy Carter (0-2) S: Todd Jones (1) | First | -- |
| Sunday, May 29 |
| » Lost to Phillies (23-26), 4-2 | Veteran's Stadium (2-1) | 27-22 | |
| » W: David West (1-4) L: Doug Drabek (7-2) S: Doug Jones (10) | First | -- |
| Monday, May 30 |
| » Defeated Marlins (24-26), 4-3 | Astrodome (14-10) | 28-22 | |
| » W: Tom Edens (4-1) L: Robb Nen (2-3) | First | -- |
| Tuesday, May 31 |
| » Defeated Marlins (24-27), 5-3 | Astrodome (15-10) | 29-22 | Won 2 |
| » W: Dave Veres (2-2) L: Richie Lewis (1-3) S: John Hudek (6) | First | -- |
| Wednesday, June 1 |
| » Lost to Marlins (25-27), 3-2 | Astrodome (15-11) | 29-23 | |
| » W: Dave Weathers (6-3) L: Shane Reynolds (3-2) S: Robb Nen (3) | First | -- |
| Friday, June 3 |
| » Defeated Phillies (26-28), 4-2 | Astrodome (16-11) | 30-23 | |
| » W: Brian Williams (2-2) L: David West (1-5) S: John Hudek (7) | First | -- |
| Saturday, June 4 |
| » Defeated Phillies (26-29), 5-1 | Astrodome (17-11) | 31-23 | Won 2 |
| » W: Doug Drabek (8-2) L: Bobby Munoz (0-2) | First | -- |
| Sunday, June 5 |
| » Defeated Phillies (26-30), 4-2 | Astrodome (18-11) | 32-23 | Won 3 |
| » W: Darryl Kile (4-2) L: Mike Williams (2-2) S: John Hudek (8) | First | -- |
| Monday, June 6 |
| » Lost to Expos (33-22), 10-5 | Stade Olympique (0-1) | 32-24 | |
| » W: Butch Henry (3-0) L: Greg Swindell (5-2) S: John Wetteland (8) | First | -- |
| Tuesday, June 7 |
| » Lost to Expos (34-22), 3-2 | Stade Olympique (0-2) | 32-25 | Lost 2 |
| » W: Gil Heredia (2-2) L: Dave Veres (2-3) S: John Wetteland (9) | Second | ½ out |
| Wednesday, June 8 |
| » Defeated Expos (34-23), 9-2 | Stade Olympique (1-2) | 33-25 | |
| » W: Brian Williams (3-2) L: Jeff Fassero (4-4) | First | -- |
| Friday, June 10 |
| » Lost to Braves (38-19), 5-2 | Astrodome (18-12) | 33-26 | |
| » W: John Smoltz (4-6) L: Doug Drabek (8-3) S: Greg McMichael (14) | Second | 1 out |
| Saturday, June 11 |
| » Defeated Braves (38-20), 7-6 | Astrodome (19-12) | 34-26 | |
| » W: Todd Jones (1-2) L: Greg McMichael (2-4) | Second | 1 out |
| Sunday, June 12 |
| » Lost to Braves (39-20), 3-1 | Astrodome (19-13) | 34-27 | |
| » W: Greg Maddux (10-2) L: Greg Swindell (5-3) | Second | 1 out |
| Monday, June 13 |
| » Lost to Giants (29-34), 5-4 | Candlestick Park (0-1) | 34-28 | Lost 2 |
| » W: William VanLandingham (2-0) L: Shane Reynolds (3-3) S: Rod Beck (13) | Second | 1 out |
| Tuesday, June 14 |
| » Defeated Giants (29-35), 7-4 | Candlestick Park (1-1) | 35-28 | |
| » W: Brian Williams (4-2) L: Salomon Torres (2-5) S: John Hudek (9) | First | -- |
| Wednesday, June 15 |
| » Defeated Giants (29-36), 7-2 | Candlestick Park (2-1) | 36-28 | Won 2 |
| » W: Doug Drabek (9-3) L: John Burkett (4-5) | First | -- |
| Thursday, June 16 |
| » Defeated Giants (29-37), 6-3 | Candlestick Park (3-1) | 37-28 | Won 3 |
| » W: Darryl Kile (5-2) L: Mark Portugal (5-6) S: John Hudek (10) | First | -- |
| Friday, June 17 |
| » Lost to Padres (25-41), 3-2 | San Diego/Jack Murphy Stadium (0-1) | 37-29 | |
| » W: Andy Benes (5-9) L: Greg Swindell (5-4) S: Trevor Hoffman (11) | First | -- |
| Saturday, June 18 |
| » Defeated Padres (25-42), 6-1 | San Diego/Jack Murphy Stadium (1-1) | 38-29 | |
| » W: Shane Reynolds (4-3) L: Mike Campbell (0-1) | First | -- |
| Sunday, June 19 |
| » Lost to Padres (26-42), 5-1 | San Diego/Jack Murphy Stadium (1-2) | 38-30 | |
| » W: Scott Sanders (3-4) L: Brian Williams (4-3) S: Trevor Hoffman (12) | Second | ½ out |
| Monday, June 20 |
| » Defeated Rockies (31-38), 5-4 | Mile High Stadium (1-0) | 39-30 | |
| » W: Doug Drabek (10-3) L: Greg Harris (3-7) S: John Hudek (11) | Second | 1 out |
| Tuesday, June 21 |
| » Lost to Rockies (32-38), 8-0 | Mile High Stadium (1-1) | 39-31 | |
| » W: David Nied (6-4) L: Darryl Kile (5-3) | Second | 1 out |
| Wednesday, June 22 |
| » Lost to Rockies (33-38), 14-5 | Mile High Stadium (1-2) | 39-32 | Lost 2 |
| » W: Lance Painter (2-2) L: Greg Swindell (5-5) | Second | 2 out |
| Friday, June 24 |
| » Defeated Dodgers (36-36), 16-4 | Astrodome (20-13) | 40-32 | |
| » W: Shane Reynolds (5-3) L: Ramon Martinez (6-4) | Second | 2½ out |
| Saturday, June 25 |
| » Lost to Dodgers (37-36), 4-2 | Astrodome (20-14) | 40-33 | |
| » W: Pedro Astacio (6-5) L: Brian Williams (4-4) S: Todd Worrell (5) | Second | 2½ out |
| Sunday, June 26 |
| » Lost to Dodgers (38-36), 5-4 | Astrodome (20-15) | 40-34 | Lost 2 |
| » W: Kevin Gross (7-4) L: Doug Drabek (10-4) S: Todd Worrell (6) | Second | 3½ out |
| Monday, June 27 |
| » Defeated Reds (43-31), 7-6 | Astrodome (21-15) | 41-34 | |
| » W: Todd Jones (2-2) L: Jeff Brantley (5-4) | Second | 2½ out |
| » Major-league debuts: Brian Hunter (Astros) |
| Tuesday, June 28 |
| » Lost to Reds (44-31), 5-3 | Astrodome (21-16) | 41-35 | |
| » W: John Smiley (7-8) L: Greg Swindell (5-6) S: Jeff Brantley (8) | Second | 3½ out |
| Wednesday, June 29 |
| » Defeated Reds (44-32), 3-1 | Astrodome (22-16) | 42-35 | |
| » W: Dave Veres (3-3) L: Chuck McElroy (1-2) S: John Hudek (12) | Second | 2½ out |
| Thursday, June 30 |
| » Defeated Cubs (32-43), 5-3 | Astrodome (23-16) | 43-35 | Won 2 |
| » W: Pete Harnisch (3-4) L: Kevin Foster (2-2) S: Todd Jones (2) | Second | 1½ out |
| Friday, July 1 |
| » Lost to Cubs (33-43), 3-2 | Astrodome (23-17) | 43-36 | |
| » W: Steve Trachsel (7-5) L: Doug Drabek (10-5) S: Randy Myers (17) | Second | 2½ out |
| Saturday, July 2 |
| » Defeated Cubs (33-44), 5-4 | Astrodome (24-17) | 44-36 | |
| » W: Shane Reynolds (6-3) L: Chuck Crim (3-2) | Second | 2½ out |
| Sunday, July 3 |
| » Defeated Cubs (33-45), 12-6 | Astrodome (25-17) | 45-36 | Won 2 |
| » W: Greg Swindell (6-6) L: Mike Morgan (1-9) | Second | 2½ out |
| Monday, July 4 |
| » Defeated Cardinals (40-39), 13-6 | Busch Stadium II (2-2) | 46-36 | Won 3 |
| » W: Brian Williams (5-4) L: Allen Watson (5-4) | Second | 2½ out |
| Tuesday, July 5 |
| » Defeated Cardinals (40-40), 3-1 | Busch Stadium II (3-2) | 47-36 | Won 4 |
| » W: Pete Harnisch (4-4) L: Vicente Palacios (1-7) S: John Hudek (13) | Second | 2½ out |
| Wednesday, July 6 |
| » Defeated Cardinals (40-41), 7-6 | Busch Stadium II (4-2) | 48-36 | Won 5 |
| » W: Todd Jones (3-2) L: Rich Rodriguez (2-4) S: John Hudek (14) | Second | 1½ out |
| Thursday, July 7 |
| » Defeated Cubs (34-49), 9-3 | Wrigley Field (3-0) | 49-36 | Won 6 |
| » W: Darryl Kile (6-3) L: Willie Banks (8-7) | Second | 1½ out |
| Friday, July 8 |
| » Lost to Cubs (35-49), 6-5 | Wrigley Field (3-1) | 49-37 | |
| » W: Jose Bautista (3-3) L: John Hudek (0-1) | Second | 2½ out |
| » Major-league debuts: Orlando Miller (Astros) |
| Saturday, July 9 |
| » Lost to Cubs (36-49), 7-3 | Wrigley Field (3-2) | 49-38 | Lost 2 |
| » W: Anthony Young (4-6) L: Brian Williams (5-5) | Second | 3½ out |
| Sunday, July 10 |
| » Defeated Cubs (36-50), 5-3 | Wrigley Field (4-2) | 50-38 | |
| » W: Pete Harnisch (5-4) L: Kevin Foster (2-3) S: John Hudek (15) | Second | 2½ out |
| Thursday, July 14 |
| » Lost to Pirates (42-45), 8-2 | Three Rivers Stadium (2-1) | 50-39 | |
| » W: Jon Lieber (5-4) L: Darryl Kile (6-4) | Second | 2½ out |
| Friday, July 15 |
| » Lost to Pirates (43-45), 11-8 | Three Rivers Stadium (2-2) | 50-40 | Lost 2 |
| » W: Ravelo Manzanillo (3-2) L: Shane Reynolds (6-4) S: Mike Dyer (2) | Second | 3½ out |
| Saturday, July 16 |
| » Defeated Pirates (43-46), 7-1 | Three Rivers Stadium (3-2) | 51-40 | |
| » W: Pete Harnisch (6-4) L: Zane Smith (9-7) | Second | 2½ out |
| Sunday, July 17 |
| » Defeated Pirates (43-47), 9-0 | Three Rivers Stadium (4-2) | 52-40 | Won 2 |
| » W: Shane Reynolds (7-4) L: Paul Wagner (5-8) | Second | 2½ out |
| Monday, July 18 |
| » Defeated Cardinals (42-47), 15-12 | Astrodome (26-17) | 53-40 | Won 3 |
| » W: Mike Hampton (2-1) L: Bryan Eversgerd (2-1) S: Todd Jones (3) | Second | 2½ out |
| Tuesday, July 19 |
| » Lost to Cardinals (43-47), 10-0 | Astrodome (26-18) | 53-41 | |
| » W: Vicente Palacios (2-7) L: Darryl Kile (6-5) | Second | 3½ out |
| Wednesday, July 20 |
| » Defeated Cardinals (43-48), 2-0 | Astrodome (27-18) | 54-41 | |
| » W: Greg Swindell (7-6) L: Bob Tewksbury (10-9) S: John Hudek (16) | Second | 2½ out |
| Thursday, July 21 |
| » Defeated Pirates (45-49), 13-6 | Astrodome (28-18) | 55-41 | Won 2 |
| » W: Pete Harnisch (7-4) L: Zane Smith (9-8) | Second | 2 out |
| Friday, July 22 |
| » Lost to Pirates (46-49), 4-1 | Astrodome (28-19) | 55-42 | |
| » W: Ravelo Manzanillo (4-2) L: Doug Drabek (10-6) S: Mike Dyer (4) | Second | 2 out |
| Saturday, July 23 |
| » Defeated Pirates (46-50), 11-0 | Astrodome (29-19) | 56-42 | |
| » W: Shane Reynolds (8-4) L: Steve Cooke (4-8) | Second | 2 out |
| Sunday, July 24 |
| » Defeated Pirates (46-51), 13-1 | Astrodome (30-19) | 57-42 | Won 2 |
| » W: Darryl Kile (7-5) L: Jon Lieber (5-5) | Second | 1 out |
| Monday, July 25 |
| » Lost to Reds (58-40), 7-4 | Riverfront Stadium (2-3) | 57-43 | |
| » W: John Smiley (11-9) L: Greg Swindell (7-7) S: Hector Carrasco (6) | Second | 2 out |
| Tuesday, July 26 |
| » Defeated Reds (58-41), 6-5 | Riverfront Stadium (3-3) | 58-43 | |
| » W: Todd Jones (4-2) L: Johnny Ruffin (6-1) | Second | 1 out |
| Wednesday, July 27 |
| » Defeated Reds (58-42), 7-1 | Riverfront Stadium (4-3) | 59-43 | Won 2 |
| » W: Brian Williams (6-5) L: Scott Service (0-2) | Second | 1 out |
| Friday, July 29 |
| » Lost to Dodgers (50-52), 7-5 | Dodger Stadium (0-4) | 59-44 | |
| » W: Ismael Valdes (2-0) L: John Hudek (0-2) | Second | ½ out |
| Saturday, July 30 |
| » Lost to Dodgers (51-52), 6-1 | Dodger Stadium (0-5) | 59-45 | Lost 2 |
| » W: Kevin Gross (8-7) L: Darryl Kile (7-6) | Second | 1½ out |
| Sunday, July 31 |
| » Lost to Dodgers (52-52), 7-1 | Dodger Stadium (0-6) | 59-46 | Lost 3 |
| » W: Ramon Martinez (10-7) L: Greg Swindell (7-8) | Second | 2½ out |
| Monday, August 1 |
| » Lost to Rockies (51-57), 8-3 | Astrodome (30-20) | 59-47 | Lost 4 |
| » W: Lance Painter (4-5) L: Pete Harnisch (7-5) | Second | 3½ out |
| Tuesday, August 2 |
| » Defeated Rockies (51-58), 3-1 | Astrodome (31-20) | 60-47 | |
| » W: Doug Drabek (11-6) L: Greg Harris (3-11) | Second | 3½ out |
| Wednesday, August 3 |
| » Defeated Rockies (51-59), 2-1 | Astrodome (32-20) | 61-47 | Won 2 |
| » W: Todd Jones (5-2) L: Bruce Ruffin (3-5) | Second | 3½ out |
| Thursday, August 4 |
| » Defeated Rockies (51-60), 6-2 | Astrodome (33-20) | 62-47 | Won 3 |
| » W: Darryl Kile (8-6) L: Kevin Ritz (4-6) | Second | 3 out |
| Friday, August 5 |
| » Defeated Giants (52-58), 12-4 | Astrodome (34-20) | 63-47 | Won 4 |
| » W: Greg Swindell (8-8) L: Mark Portugal (10-8) | Second | 2 out |
| Saturday, August 6 |
| » Defeated Giants (52-59), 8-7 | Astrodome (35-20) | 64-47 | Won 5 |
| » W: Pete Harnisch (8-5) L: William VanLandingham (7-2) S: Dave Veres (1) | Second | 1 out |
| Sunday, August 7 |
| » Defeated Giants (52-60), 7-4 | Astrodome (36-20) | 65-47 | Won 6 |
| » W: Doug Drabek (12-6) L: Bill Swift (8-7) S: Todd Jones (4) | Second | 1 out |
| Tuesday, August 9 |
| » Lost to Padres (46-69), 4-3 | Astrodome (36-21) | 65-48 | |
| » W: Andy Ashby (6-11) L: Shane Reynolds (8-5) S: Trevor Hoffman (19) | Second | 1½ out |
| Wednesday, August 10 |
| » Defeated Padres (46-70), 3-1 | Astrodome (37-21) | 66-48 | |
| » W: Darryl Kile (9-6) L: Andy Benes (6-14) S: Todd Jones (5) | Second | ½ out |
| Thursday, August 11 |
| » Lost to Padres (47-70), 8-6 | Astrodome (37-22) | 66-49 | |
| » W: Joey Hamilton (9-6) L: Greg Swindell (8-9) S: Trevor Hoffman (20) | Second | ½ out |
Game information provided by Retrosheet (www.retrosheet.org) |