| Monday, April 5 |
| » Lost to Mets (1-0), 3-0 | Shea Stadium (0-1) | 0-1 | |
| » W: Dwight Gooden (1-0) L: David Nied (0-1) | Third | 1 out |
| Wednesday, April 7 |
| » Lost to Mets (2-0), 6-1 | Shea Stadium (0-2) | 0-2 | Lost 2 |
| » W: Bret Saberhagen (1-0) L: Bruce Ruffin (0-1) | Fourth | 1½ out |
| Friday, April 9 |
| » Defeated Expos (2-2), 11-4 | Mile High Stadium (1-0) | 1-2 | |
| » W: Bryn Smith (1-0) L: Kent Bottenfield (0-1) | Third | 2 out |
| Saturday, April 10 |
| » Defeated Expos (2-3), 9-5 | Mile High Stadium (2-0) | 2-2 | Won 2 |
| » W: David Nied (1-1) L: Dennis Martinez (0-2) | Second | 1 out |
| Sunday, April 11 |
| » Lost to Expos (3-3), 19-9 | Mile High Stadium (2-1) | 2-3 | |
| » W: Jimmy Jones (1-0) L: Butch Henry (0-1) | Fourth | 2 out |
| Tuesday, April 13 |
| » Lost to Mets (3-3), 8-4 | Mile High Stadium (2-2) | 2-4 | Lost 2 |
| » W: Bret Saberhagen (2-0) L: Darren Holmes (0-1) | Fifth | 2½ out |
| Wednesday, April 14 |
| » Lost to Mets (4-3), 6-3 | Mile High Stadium (2-3) | 2-5 | Lost 3 |
| » W: Sid Fernandez (1-0) L: Bryn Smith (1-1) S: Mike Maddux (1) | Fifth | 2½ out |
| Thursday, April 15 |
| » Defeated Mets (4-4), 5-3 | Mile High Stadium (3-3) | 3-5 | |
| » W: David Nied (2-1) L: Dwight Gooden (1-2) | Fourth | 2 out |
| Friday, April 16 |
| » Lost to Expos (5-5), 3-2 | Stade Olympique (0-1) | 3-6 | |
| » W: Kent Bottenfield (1-1) L: Butch Henry (0-2) S: Mel Rojas (4) | Fifth | 3 out |
| Saturday, April 17 |
| » Defeated Expos (5-6), 9-1 | Stade Olympique (1-1) | 4-6 | |
| » W: Bruce Ruffin (1-1) L: Dennis Martinez (0-3) | Fifth | 2 out |
| Sunday, April 18 |
| » Lost to Expos (6-6), 4-2 | Stade Olympique (1-2) | 4-7 | |
| » W: Ken Hill (2-0) L: Gary Wayne (0-1) | Sixth | 3 out |
| Tuesday, April 20 |
| » Lost to Cardinals (8-5), 5-0 | Busch Stadium II (0-1) | 4-8 | Lost 2 |
| » W: Rene Arocha (3-0) L: Bryn Smith (1-2) S: Omar Olivares (1) | Sixth | 4 out |
| Wednesday, April 21 |
| » Defeated Cardinals (8-6), 11-2 | Busch Stadium II (1-1) | 5-8 | |
| » W: David Nied (3-1) L: Joe Magrane (0-2) | Fifth | 3 out |
| » Major-league debuts: Tom Urbani (Cardinals) |
| Thursday, April 22 |
| » Lost to Cardinals (9-6), 5-2 | Busch Stadium II (1-2) | 5-9 | |
| » W: Mike Perez (2-1) L: Gary Wayne (0-2) S: Lee Smith (6) | Sixth | 4 out |
| Friday, April 23 |
| » Defeated Marlins (5-11), 5-4 | Mile High Stadium (4-3) | 6-9 | |
| » W: Steve Reed (1-0) L: Chris Hammond (0-3) S: Darren Holmes (1) | Fourth | 3 out |
| » Major-league debuts: Matt Turner (Marlins) |
| Saturday, April 24 |
| » Lost to Marlins (6-11), 2-1 | Mile High Stadium (4-4) | 6-10 | |
| » W: Luis Aquino (1-1) L: Andy Ashby (0-1) S: Bryan Harvey (5) | Fifth | 4 out |
| Sunday, April 25 |
| » Lost to Marlins (7-11), 11-1 | Mile High Stadium (4-5) | 6-11 | Lost 2 |
| » W: Ryan Bowen (2-1) L: Bryn Smith (1-3) | Fifth | 4 out |
| Monday, April 26 |
| » Lost to Cubs (10-8), 6-3 | Mile High Stadium (4-6) | 6-12 | Lost 3 |
| » W: Mike Harkey (3-0) L: David Nied (3-2) S: Randy Myers (6) | Sixth | 4 out |
| Tuesday, April 27 |
| » Defeated Cubs (10-9), 11-2 | Mile High Stadium (5-6) | 7-12 | |
| » W: Butch Henry (1-2) L: Mike Morgan (1-4) | Fifth | 4 out |
| Wednesday, April 28 |
| » Lost to Cardinals (12-9), 7-6 | Mile High Stadium (5-7) | 7-13 | |
| » W: Rob Murphy (1-1) L: Darren Holmes (0-2) S: Lee Smith (9) | Sixth | 5 out |
| Thursday, April 29 |
| » Lost to Cardinals (13-9), 5-2 | Mile High Stadium (5-8) | 7-14 | Lost 2 |
| » W: Bob Tewksbury (1-3) L: Andy Ashby (0-2) S: Lee Smith (10) | Seventh | 6 out |
| Friday, April 30 |
| » Defeated Marlins (10-13), 6-2 | Joe Robbie Stadium (1-0) | 8-14 | |
| » W: Armando Reynoso (1-0) L: Ryan Bowen (2-2) | Fifth | 6 out |
| » Major-league debuts: Scott Fredrickson (Rockies) |
| Saturday, May 1 |
| » Lost to Marlins (11-13), 7-6 | Joe Robbie Stadium (1-1) | 8-15 | |
| » W: Bryan Harvey (1-1) L: Steve Reed (1-1) | Seventh | 7 out |
| Sunday, May 2 |
| » Defeated Marlins (11-14), 2-1 | Joe Robbie Stadium (2-1) | 9-15 | |
| » W: Butch Henry (2-2) L: Jack Armstrong (2-3) S: Darren Holmes (2) | Fifth | 7 out |
| Tuesday, May 4 |
| » Defeated Cubs (12-13), 14-13 | Wrigley Field (1-0) | 10-15 | Won 2 |
| » W: Willie Blair (1-0) L: Chuck McElroy (1-1) | Fifth | 6 out |
| Wednesday, May 5 |
| » Lost to Cubs (13-13), 3-2 | Wrigley Field (1-1) | 10-16 | |
| » W: Greg Hibbard (2-2) L: Armando Reynoso (1-1) S: Randy Myers (8) | Sixth | 7 out |
| Thursday, May 6 |
| » Lost to Braves (15-15), 13-3 | Mile High Stadium (5-9) | 10-17 | Lost 2 |
| » W: John Smoltz (3-3) L: David Nied (3-3) | Sixth | 7½ out |
| Friday, May 7 |
| » Lost to Braves (16-15), 13-5 | Mile High Stadium (5-10) | 10-18 | Lost 3 |
| » W: Marvin Freeman (1-0) L: Jeff Parrett (0-1) | Seventh | 8½ out |
| Saturday, May 8 |
| » Lost to Braves (17-15), 8-7 | Mile High Stadium (5-11) | 10-19 | Lost 4 |
| » W: Kent Mercker (2-0) L: Scott Fredrickson (0-1) S: Mike Stanton (11) | Sixth | 8½ out |
| Sunday, May 9 |
| » Lost to Braves (18-15), 12-7 | Mile High Stadium (5-12) | 10-20 | Lost 5 |
| » W: Greg McMichael (1-1) L: Steve Reed (1-2) | Seventh | 8½ out |
| Monday, May 10 |
| » Defeated Giants (19-13), 7-4 | Mile High Stadium (6-12) | 11-20 | |
| » W: Armando Reynoso (2-1) L: Trevor Wilson (0-3) | Sixth | 8 out |
| Tuesday, May 11 |
| » Lost to Giants (20-13), 5-3 | Mile High Stadium (6-13) | 11-21 | |
| » W: Bill Swift (4-1) L: David Nied (3-4) S: Rod Beck (8) | Seventh | 8½ out |
| Wednesday, May 12 |
| » Lost to Giants (21-13), 8-2 | Mile High Stadium (6-14) | 11-22 | Lost 2 |
| » W: Bud Black (3-0) L: Butch Henry (2-3) | Seventh | 9½ out |
| Thursday, May 13 |
| » Lost to Giants (22-13), 13-8 | Mile High Stadium (6-15) | 11-23 | Lost 3 |
| » W: John Burkett (6-0) L: Bruce Ruffin (1-2) | Seventh | 10½ out |
| Friday, May 14 |
| » Lost to Reds (17-18), 13-5 | Riverfront Stadium (0-1) | 11-24 | Lost 4 |
| » W: Tim Pugh (3-3) L: Andy Ashby (0-3) | Sixth | 10½ out |
| » Major-league debuts: Jay Gainer (Rockies) |
| Saturday, May 15 |
| » Lost to Reds (18-18), 5-3 | Riverfront Stadium (0-2) | 11-25 | Lost 5 |
| » W: Milt Hill (3-0) L: Armando Reynoso (2-2) S: Jeff Reardon (6) | Sixth | 11½ out |
| Sunday, May 16 |
| » Lost to Reds (19-18), 14-2 | Riverfront Stadium (0-3) | 11-26 | Lost 6 |
| » W: John Roper (1-0) L: David Nied (3-5) | Sixth | 12½ out |
| » Major-league debuts: John Roper (Reds) |
| Monday, May 17 |
| » Lost to Padres (15-22), 4-0 | San Diego/Jack Murphy Stadium (0-1) | 11-27 | Lost 7 |
| » W: Andy Benes (6-3) L: Butch Henry (2-4) | Sixth | 13½ out |
| Tuesday, May 18 |
| » Defeated Padres (15-23), 2-1 | San Diego/Jack Murphy Stadium (1-1) | 12-27 | |
| » W: Gary Wayne (1-2) L: Rich Rodriguez (1-2) S: Darren Holmes (3) | Seventh | 13½ out |
| Wednesday, May 19 |
| » Lost to Padres (16-23), 7-3 | San Diego/Jack Murphy Stadium (1-2) | 12-28 | |
| » W: Greg Harris (4-5) L: Lance Painter (0-1) | Seventh | 14½ out |
| » Major-league debuts: Lance Painter (Rockies) |
| Thursday, May 20 |
| » Lost to Padres (17-23), 5-4 | San Diego/Jack Murphy Stadium (1-3) | 12-29 | Lost 2 |
| » W: Gene Harris (3-0) L: Darren Holmes (0-3) | Seventh | 15½ out |
| Friday, May 21 |
| » Lost to Dodgers (18-22), 8-0 | Dodger Stadium (0-1) | 12-30 | Lost 3 |
| » W: Orel Hershiser (5-4) L: David Nied (3-6) | Seventh | 16½ out |
| Saturday, May 22 |
| » Lost to Dodgers (19-22), 4-3 | Dodger Stadium (0-2) | 12-31 | Lost 4 |
| » W: Roger McDowell (2-0) L: Butch Henry (2-5) S: Jim Gott (6) | Seventh | 16½ out |
| Sunday, May 23 |
| » Lost to Dodgers (20-22), 4-0 | Dodger Stadium (0-3) | 12-32 | Lost 5 |
| » W: Ramon Martinez (3-3) L: Willie Blair (1-1) | Seventh | 17½ out |
| Tuesday, May 25 |
| » Defeated Astros (23-20), 7-5 | Astrodome (1-0) | 13-32 | |
| » W: Gary Wayne (2-2) L: Xavier Hernandez (2-1) S: Andy Ashby (1) | Seventh | 17½ out |
| Wednesday, May 26 |
| » Defeated Astros (23-21), 3-2 | Astrodome (2-0) | 14-32 | Won 2 |
| » W: Bryn Smith (2-3) L: Doug Jones (1-4) S: Jeff Parrett (1) | Seventh | 16½ out |
| Thursday, May 27 |
| » Lost to Astros (24-21), 8-0 | Astrodome (2-1) | 14-33 | |
| » W: Doug Drabek (5-5) L: David Nied (3-7) | Seventh | 16½ out |
| Friday, May 28 |
| » Lost to Phillies (32-14), 15-9 | Mile High Stadium (6-16) | 14-34 | Lost 2 |
| » W: Ben Rivera (3-2) L: Butch Henry (2-6) | Sixth | 16½ out |
| Saturday, May 29 |
| » Lost to Phillies (33-14), 6-0 | Mile High Stadium (6-17) | 14-35 | Lost 3 |
| » W: Terry Mulholland (6-4) L: Willie Blair (1-2) | Sixth | 17½ out |
| Sunday, May 30 |
| » Lost to Phillies (34-14), 18-1 | Mile High Stadium (6-18) | 14-36 | Lost 4 |
| » W: Tommy Greene (7-0) L: Lance Painter (0-2) | Seventh | 18½ out |
| » Major-league debuts: Pedro Castellano (Rockies) |
| Monday, May 31 |
| » Defeated Pirates (23-25), 6-2 | Mile High Stadium (7-18) | 15-36 | |
| » W: Armando Reynoso (3-2) L: Tim Wakefield (3-5) | Seventh | 18 out |
| Tuesday, June 1 |
| » Lost to Pirates (24-25), 8-6 | Mile High Stadium (7-19) | 15-37 | |
| » W: Bob Walk (7-3) L: Bryn Smith (2-4) | Sixth | 18½ out |
| Wednesday, June 2 |
| » Lost to Pirates (25-25), 5-3 | Mile High Stadium (7-20) | 15-38 | Lost 2 |
| » W: Mark Petkovsek (1-0) L: Jeff Parrett (0-2) S: Stan Belinda (11) | Seventh | 19½ out |
| Friday, June 4 |
| » Defeated Phillies (36-16), 2-1 | Veteran's Stadium (1-0) | 16-38 | |
| » W: Willie Blair (2-2) L: Terry Mulholland (6-5) S: Gary Wayne (1) | Seventh | 18 out |
| Saturday, June 5 |
| » Lost to Phillies (37-16), 6-2 | Veteran's Stadium (1-1) | 16-39 | |
| » W: Tommy Greene (8-0) L: Armando Reynoso (3-3) | Seventh | 19 out |
| Sunday, June 6 |
| » Lost to Phillies (38-16), 11-7 | Veteran's Stadium (1-2) | 16-40 | Lost 2 |
| » W: Curt Schilling (7-1) L: Andy Ashby (0-4) | Seventh | 20 out |
| » Major-league debuts: Jayhawk Owens (Rockies) |
| Tuesday, June 8 |
| » Defeated Pirates (27-28), 4-1 | Three Rivers Stadium (1-0) | 17-40 | |
| » W: Bruce Ruffin (2-2) L: Paul Wagner (1-3) S: Keith Shepherd (1) | Seventh | 19 out |
| Wednesday, June 9 |
| » Lost to Pirates (28-28), 4-1 | Three Rivers Stadium (1-1) | 17-41 | |
| » W: Denny Neagle (2-1) L: Willie Blair (2-3) S: Stan Belinda (13) | Seventh | 20 out |
| Friday, June 11 |
| » Defeated Astros (32-26), 5-4 | Mile High Stadium (8-20) | 18-41 | |
| » W: Jeff Parrett (1-2) L: Xavier Hernandez (2-2) S: Darren Holmes (4) | Seventh | 20 out |
| Saturday, June 12 |
| » Defeated Astros (32-27), 14-11 | Mile High Stadium (9-20) | 19-41 | Won 2 |
| » W: Keith Shepherd (1-0) L: Doug Jones (3-5) | Seventh | 20 out |
| Sunday, June 13 |
| » Defeated Astros (32-28), 9-1 | Mile High Stadium (10-20) | 20-41 | Won 3 |
| » W: Bruce Ruffin (3-2) L: Greg Swindell (5-6) | Sixth | 20 out |
| Monday, June 14 |
| » Lost to Dodgers (33-28), 9-4 | Mile High Stadium (10-21) | 20-42 | |
| » W: Pedro Astacio (5-4) L: Willie Blair (2-4) | Seventh | 20½ out |
| Tuesday, June 15 |
| » Lost to Dodgers (34-28), 12-4 | Mile High Stadium (10-22) | 20-43 | Lost 2 |
| » W: Roger McDowell (3-0) L: Keith Shepherd (1-1) | Seventh | 20½ out |
| Wednesday, June 16 |
| » Defeated Dodgers (34-29), 7-6 | Mile High Stadium (11-22) | 21-43 | |
| » W: Armando Reynoso (4-3) L: Kevin Gross (5-5) S: Mark Grant (1) | Seventh | 20½ out |
| Friday, June 18 |
| » Lost to Padres (27-39), 11-1 | Mile High Stadium (11-23) | 21-44 | |
| » W: Greg Harris (7-7) L: Bruce Ruffin (3-3) | Sixth | 22 out |
| Saturday, June 19 |
| » Defeated Padres (27-40), 17-3 | Mile High Stadium (12-23) | 22-44 | |
| » W: Willie Blair (3-4) L: Kerry Taylor (0-5) | Sixth | 22 out |
| Sunday, June 20 |
| » Defeated Padres (27-41), 3-1 | Mile High Stadium (13-23) | 23-44 | Won 2 |
| » W: Steve Reed (2-2) L: Roger Mason (0-5) S: Darren Holmes (5) | Seventh | 22 out |
| Monday, June 21 |
| » Defeated Reds (32-38), 5-4 | Mile High Stadium (14-23) | 24-44 | Won 3 |
| » W: Steve Reed (3-2) L: Jeff Reardon (1-1) | Seventh | 22 out |
| Tuesday, June 22 |
| » Lost to Reds (33-38), 16-13 | Mile High Stadium (14-24) | 24-45 | |
| » W: Kevin Wickander (1-0) L: Mark Grant (0-1) S: Rob Dibble (6) | Seventh | 22 out |
| Wednesday, June 23 |
| » Defeated Reds (33-39), 15-5 | Mile High Stadium (15-24) | 25-45 | |
| » W: Jeff Parrett (2-2) L: Tim Pugh (3-9) | Sixth | 22 out |
| Thursday, June 24 |
| » Lost to Giants (49-24), 17-2 | Candlestick Park (0-1) | 25-46 | |
| » W: John Burkett (11-2) L: Willie Blair (3-5) | Seventh | 23 out |
| Friday, June 25 |
| » Lost to Giants (50-24), 7-2 | Candlestick Park (0-2) | 25-47 | Lost 2 |
| » W: Bryan Hickerson (1-1) L: Butch Henry (2-7) | Seventh | 24 out |
| Saturday, June 26 |
| » Defeated Giants (50-25), 5-1 | Candlestick Park (1-2) | 26-47 | |
| » W: Armando Reynoso (5-3) L: Trevor Wilson (5-4) | Sixth | 23 out |
| Sunday, June 27 |
| » Lost to Giants (51-25), 5-0 | Candlestick Park (1-3) | 26-48 | |
| » W: Bill Swift (10-4) L: Curt Leskanic (0-1) | Sixth | 24 out |
| » Major-league debuts: Curtis Leskanic (Rockies) |
| Tuesday, June 29 |
| » Lost to Braves (43-34), 6-4 | Atlanta-Fulton County Stadium (0-1) | 26-49 | Lost 2 |
| » W: John Smoltz (7-7) L: Bruce Ruffin (3-4) S: Mike Stanton (21) | Seventh | 24½ out |
| Wednesday, June 30 |
| » Lost to Braves (44-34), 3-2 | Atlanta-Fulton County Stadium (0-2) | 26-50 | Lost 3 |
| » W: Mark Wohlers (2-0) L: Keith Shepherd (1-2) | Seventh | 24½ out |
| Thursday, July 1 |
| » Lost to Braves (45-34), 4-0 | Atlanta-Fulton County Stadium (0-3) | 26-51 | Lost 4 |
| » W: Tom Glavine (10-3) L: Armando Reynoso (5-4) | Seventh | 25 out |
| Friday, July 2 |
| » Lost to Cubs (38-38), 11-8 | Mile High Stadium (15-25) | 26-52 | Lost 5 |
| » W: Jose Bautista (3-2) L: Keith Shepherd (1-3) S: Randy Myers (25) | Seventh | 26 out |
| Saturday, July 3 |
| » Defeated Cubs (38-39), 5-4 | Mile High Stadium (16-25) | 27-52 | |
| » W: Steve Reed (4-2) L: Randy Myers (1-2) | Sixth | 25 out |
| Sunday, July 4 |
| » Defeated Cubs (38-40), 3-1 | Mile High Stadium (17-25) | 28-52 | Won 2 |
| » W: Jeff Parrett (3-2) L: Mike Morgan (5-9) S: Darren Holmes (6) | Sixth | 25 out |
| Monday, July 5 |
| » Lost to Cubs (39-40), 10-1 | Mile High Stadium (17-26) | 28-53 | |
| » W: Mike Harkey (6-2) L: Willie Blair (3-6) | Sixth | 26 out |
| Tuesday, July 6 |
| » Defeated Marlins (36-46), 8-3 | Mile High Stadium (18-26) | 29-53 | |
| » W: Armando Reynoso (6-4) L: Charlie Hough (4-9) | Seventh | 26 out |
| Wednesday, July 7 |
| » Defeated Marlins (36-47), 6-5 | Mile High Stadium (19-26) | 30-53 | Won 2 |
| » W: Steve Reed (5-2) L: Bryan Harvey (1-2) | Seventh | 25 out |
| Thursday, July 8 |
| » Defeated Marlins (36-48), 3-2 | Mile High Stadium (20-26) | 31-53 | Won 3 |
| » W: Curt Leskanic (1-1) L: Pat Rapp (0-1) S: Darren Holmes (7) | Seventh | 25 out |
| » Major-league debuts: Marcus Moore (Rockies) |
| Friday, July 9 |
| » Defeated Cardinals (50-35), 5-4 | Busch Stadium II (2-2) | 32-53 | Won 4 |
| » W: Marcus Moore (1-0) L: Lee Smith (2-2) S: Darren Holmes (8) | Seventh | 25 out |
| Saturday, July 10 |
| » Lost to Cardinals (51-35), 9-3 | Busch Stadium II (2-3) | 32-54 | |
| » W: Donovan Osborne (8-3) L: Butch Henry (2-8) | Sixth | 25 out |
| Sunday, July 11 |
| » Defeated Cardinals (51-36), 4-1 | Busch Stadium II (3-3) | 33-54 | |
| » W: Armando Reynoso (7-4) L: Bob Tewksbury (9-7) S: Steve Reed (1) | Fifth | 25 out |
| Thursday, July 15 |
| » Lost to Cubs (42-45), 1-0 | Wrigley Field (1-2) | 33-55 | |
| » W: Mike Morgan (7-9) L: Willie Blair (3-7) | Seventh | 26 out |
| » Major-league debuts: Kevin Roberson (Cubs) Roberto Mejia (Rockies) |
| Friday, July 16 |
| » Lost to Cubs (43-45), 8-2 | Wrigley Field (1-3) | 33-56 | Lost 2 |
| » W: Jose Guzman (8-7) L: Curt Leskanic (1-2) | Seventh | 27 out |
| Saturday, July 17 |
| » Lost to Cubs (44-45), 5-1 | Wrigley Field (1-4) | 33-57 | Lost 3 |
| » W: Mike Harkey (7-3) L: Armando Reynoso (7-5) | Seventh | 27 out |
| Sunday, July 18 |
| » Lost to Cubs (45-45), 12-2 | Wrigley Field (1-5) | 33-58 | Lost 4 |
| » W: Greg Hibbard (8-6) L: Jeff Parrett (3-3) | Seventh | 27 out |
| Monday, July 19 |
| » Lost to Marlins (39-53), 3-1 | Joe Robbie Stadium (2-2) | 33-59 | Lost 5 |
| » W: Ryan Bowen (5-9) L: Kent Bottenfield (2-6) S: Bryan Harvey (26) | Seventh | 28 out |
| Tuesday, July 20 |
| » Defeated Marlins (39-54), 6-3 | Joe Robbie Stadium (3-2) | 34-59 | |
| » W: Willie Blair (4-7) L: Chris Hammond (10-6) S: Darren Holmes (9) | Seventh | 28 out |
| Wednesday, July 21 |
| » Lost to Marlins (40-54), 6-4 | Joe Robbie Stadium (3-3) | 34-60 | |
| » W: Pat Rapp (1-2) L: Curt Leskanic (1-3) S: Bryan Harvey (27) | Sixth | 29 out |
| Thursday, July 22 |
| » Defeated Cardinals (55-40), 7-6 | Mile High Stadium (21-26) | 35-60 | |
| » W: Darren Holmes (1-3) L: Todd Burns (0-5) | Seventh | 29 out |
| Friday, July 23 |
| » Lost to Cardinals (56-40), 13-11 | Mile High Stadium (21-27) | 35-61 | |
| » W: Allen Watson (2-0) L: Steve Reed (5-3) S: Lee Smith (34) | Seventh | 29 out |
| Saturday, July 24 |
| » Defeated Cardinals (56-41), 9-8 | Mile High Stadium (22-27) | 36-61 | |
| » W: Kent Bottenfield (3-6) L: Donovan Osborne (9-4) S: Darren Holmes (10) | Sixth | 29 out |
| Sunday, July 25 |
| » Lost to Cardinals (57-41), 5-4 | Mile High Stadium (22-28) | 36-62 | |
| » W: Omar Olivares (3-2) L: Gary Wayne (2-3) S: Lee Guetterman (1) | Sixth | 30 out |
| Monday, July 26 |
| » Lost to Braves (59-42), 12-7 | Mile High Stadium (22-29) | 36-63 | Lost 2 |
| » W: Greg Maddux (11-8) L: Curt Leskanic (1-4) | Seventh | 30 out |
| Tuesday, July 27 |
| » Lost to Braves (60-42), 10-5 | Mile High Stadium (22-30) | 36-64 | Lost 3 |
| » W: John Smoltz (9-8) L: Armando Reynoso (7-6) | Sixth | 31 out |
| Wednesday, July 28 |
| » Lost to Braves (61-42), 3-2 | Mile High Stadium (22-31) | 36-65 | Lost 4 |
| » W: Mark Wohlers (5-0) L: Steve Reed (5-4) S: Greg McMichael (1) | Sixth | 31 out |
| Friday, July 30 |
| » Lost to Giants (69-35), 10-4 | Mile High Stadium (22-32) | 36-66 | Lost 5 |
| » W: Greg Brummett (2-3) L: Greg Harris (10-10) | Seventh | 32 out |
| Saturday, July 31 |
| » Lost to Giants (70-35), 4-3 | Mile High Stadium (22-33) | 36-67 | Lost 6 |
| » W: Bill Swift (15-5) L: Kent Bottenfield (3-7) S: Rod Beck (30) | Seventh | 33 out |
| Sunday, August 1 |
| » Lost to Giants (71-35), 6-5 | Mile High Stadium (22-34) | 36-68 | Lost 7 |
| » W: John Burkett (16-4) L: Armando Reynoso (7-7) S: Rod Beck (31) | Seventh | 34 out |
| Monday, August 2 |
| » Lost to Reds (54-54), 6-2 | Riverfront Stadium (0-4) | 36-69 | Lost 8 |
| » W: Tim Pugh (7-10) L: Willie Blair (4-8) | Seventh | 34½ out |
| Tuesday, August 3 |
| » Lost to Reds (55-54), 5-4 | Riverfront Stadium (0-5) | 36-70 | Lost 9 |
| » W: Jerry Spradlin (1-0) L: Curt Leskanic (1-5) | Seventh | 35½ out |
| Wednesday, August 4 |
| » Lost to Reds (56-54), 9-3 | Riverfront Stadium (0-6) | 36-71 | Lost 10 |
| » W: John Roper (2-1) L: Greg Harris (10-11) | Seventh | 35½ out |
| Thursday, August 5 |
| » Lost to Reds (57-54), 11-4 | Riverfront Stadium (0-7) | 36-72 | Lost 11 |
| » W: Jose Rijo (10-5) L: Kent Bottenfield (3-8) | Seventh | 36½ out |
| Friday, August 6 |
| » Lost to Padres (43-67), 6-3 | San Diego/Jack Murphy Stadium (1-4) | 36-73 | Lost 12 |
| » W: Andy Benes (13-7) L: Armando Reynoso (7-8) S: Trevor Hoffman (3) | Seventh | 38 out |
| » Lost to Padres (44-67), 6-2 | San Diego/Jack Murphy Stadium (1-5) | 36-74 | Lost 13 |
| » W: Scott Sanders (1-0) L: Willie Blair (4-9) | Seventh | 38 out |
| » Major-league debuts: Scott Sanders (Padres) |
| Sunday, August 8 |
| » Defeated Padres (44-68), 5-2 | San Diego/Jack Murphy Stadium (2-5) | 37-74 | |
| » W: Mo Sanford (1-0) L: Doug Brocail (2-8) S: Darren Holmes (11) | Seventh | 36½ out |
| Monday, August 9 |
| » Defeated Dodgers (57-54), 3-2 | Dodger Stadium (1-3) | 38-74 | Won 2 |
| » W: Steve Reed (6-4) L: Jim Gott (4-6) S: Darren Holmes (12) | Seventh | 36½ out |
| Tuesday, August 10 |
| » Defeated Dodgers (57-55), 4-2 | Dodger Stadium (2-3) | 39-74 | Won 3 |
| » W: Kent Bottenfield (4-8) L: Pedro Astacio (8-7) | Seventh | 36½ out |
| Wednesday, August 11 |
| » Defeated Dodgers (57-56), 3-2 | Dodger Stadium (3-3) | 40-74 | Won 4 |
| » W: Armando Reynoso (8-8) L: Ramon Martinez (8-7) S: Steve Reed (2) | Seventh | 36½ out |
| Thursday, August 12 |
| » Defeated Dodgers (57-57), 4-1 | Dodger Stadium (4-3) | 41-74 | Won 5 |
| » W: Willie Blair (5-9) L: Orel Hershiser (8-12) | Seventh | 36 out |
| Friday, August 13 |
| » Defeated Astros (60-56), 5-3 | Astrodome (3-1) | 42-74 | Won 6 |
| » W: Gary Wayne (3-3) L: Doug Jones (3-9) S: Darren Holmes (13) | Seventh | 36 out |
| Saturday, August 14 |
| » Lost to Astros (61-56), 9-0 | Astrodome (3-2) | 42-75 | |
| » W: Pete Harnisch (11-8) L: Greg Harris (10-12) | Seventh | 36 out |
| Sunday, August 15 |
| » Defeated Astros (61-57), 4-3 | Astrodome (4-2) | 43-75 | |
| » W: Bruce Ruffin (4-4) L: Xavier Hernandez (3-3) S: Darren Holmes (14) | Seventh | 36 out |
| Tuesday, August 17 |
| » Lost to Phillies (76-43), 10-7 | Mile High Stadium (22-35) | 43-76 | |
| » W: Ben Rivera (11-6) L: Armando Reynoso (8-9) S: Mitch Williams (33) | Seventh | 36 out |
| Wednesday, August 18 |
| » Lost to Phillies (77-43), 7-6 | Mile High Stadium (22-36) | 43-77 | Lost 2 |
| » W: Bobby Thigpen (2-0) L: Bruce Ruffin (4-5) S: Mitch Williams (34) | Seventh | 37 out |
| Thursday, August 19 |
| » Defeated Phillies (77-44), 6-5 | Mile High Stadium (23-36) | 44-77 | |
| » W: Marcus Moore (2-0) L: Roger Mason (4-9) S: Darren Holmes (15) | Seventh | 37 out |
| Saturday, August 21 |
| » Defeated Mets (42-79), 4-3 | Mile High Stadium (24-36) | 45-77 | Won 2 |
| » W: Greg Harris (11-12) L: Jeff Innis (1-3) S: Darren Holmes (16) | Sixth | 36 out |
| » Defeated Mets (42-80), 8-6 | Mile High Stadium (25-36) | 46-77 | Won 3 |
| » W: Steve Reed (7-4) L: Bobby Jones (1-1) S: Darren Holmes (17) | Sixth | 36 out |
| Sunday, August 22 |
| » Defeated Mets (42-81), 4-3 | Mile High Stadium (26-36) | 47-77 | Won 4 |
| » W: Mike Munoz (1-1) L: Sid Fernandez (2-4) S: Steve Reed (3) | Sixth | 36 out |
| Monday, August 23 |
| » Defeated Phillies (78-47), 3-2 | Veteran's Stadium (2-2) | 48-77 | Won 5 |
| » W: Gary Wayne (4-3) L: Roger Mason (4-10) S: Darren Holmes (18) | Sixth | 35 out |
| Tuesday, August 24 |
| » Lost to Phillies (79-47), 4-2 | Veteran's Stadium (2-3) | 48-78 | |
| » W: Danny Jackson (10-9) L: Willie Blair (5-10) S: Mitch Williams (36) | Sixth | 35 out |
| Wednesday, August 25 |
| » Lost to Phillies (80-47), 8-5 | Veteran's Stadium (2-4) | 48-79 | Lost 2 |
| » W: Curt Schilling (11-6) L: Mo Sanford (1-1) | Seventh | 35 out |
| Thursday, August 26 |
| » Lost to Mets (44-83), 7-1 | Shea Stadium (0-3) | 48-80 | Lost 3 |
| » W: Dwight Gooden (12-14) L: Greg Harris (11-13) | Seventh | 35½ out |
| Friday, August 27 |
| » Lost to Mets (45-83), 3-2 | Shea Stadium (0-4) | 48-81 | Lost 4 |
| » W: Sid Fernandez (3-4) L: Kent Bottenfield (4-9) S: Jeff Innis (3) | Seventh | 35½ out |
| Saturday, August 28 |
| » Defeated Mets (45-84), 7-5 | Shea Stadium (1-4) | 49-81 | |
| » W: Armando Reynoso (9-9) L: Bobby Jones (1-2) S: Darren Holmes (19) | Seventh | 35 out |
| Sunday, August 29 |
| » Defeated Mets (45-85), 6-1 | Shea Stadium (2-4) | 50-81 | Won 2 |
| » W: Lance Painter (1-2) L: Frank Tanana (6-13) | Seventh | 35 out |
| Monday, August 30 |
| » Lost to Expos (72-60), 6-1 | Mile High Stadium (26-37) | 50-82 | |
| » W: Jeff Fassero (10-3) L: Mo Sanford (1-2) S: Mel Rojas (10) | Seventh | 36 out |
| Tuesday, August 31 |
| » Lost to Expos (73-60), 14-3 | Mile High Stadium (26-38) | 50-83 | Lost 2 |
| » W: Gil Heredia (3-2) L: Greg Harris (11-14) | Seventh | 36 out |
| Wednesday, September 1 |
| » Lost to Expos (74-60), 11-3 | Mile High Stadium (26-39) | 50-84 | Lost 3 |
| » W: Dennis Martinez (13-8) L: Kent Bottenfield (4-10) | Seventh | 37 out |
| » Major-league debuts: Rondell White (Expos) |
| Friday, September 3 |
| » Defeated Pirates (63-72), 7-6 | Mile High Stadium (27-39) | 51-84 | |
| » W: Darren Holmes (2-3) L: Mark Dewey (1-1) | Seventh | 36½ out |
| Saturday, September 4 |
| » Defeated Pirates (63-73), 10-4 | Mile High Stadium (28-39) | 52-84 | Won 2 |
| » W: Lance Painter (2-2) L: Tim Wakefield (4-9) | Seventh | 36½ out |
| Sunday, September 5 |
| » Defeated Pirates (63-74), 4-1 | Mile High Stadium (29-39) | 53-84 | Won 3 |
| » W: Bruce Ruffin (5-5) L: Bob Walk (12-13) S: Darren Holmes (20) | Sixth | 35½ out |
| Monday, September 6 |
| » Lost to Expos (77-61), 4-3 | Stade Olympique (1-3) | 53-85 | |
| » W: Tim Scott (5-2) L: Steve Reed (7-5) S: John Wetteland (34) | Sixth | 36½ out |
| Tuesday, September 7 |
| » Lost to Expos (78-61), 4-3 | Stade Olympique (1-4) | 53-86 | Lost 2 |
| » W: Dennis Martinez (14-8) L: Marcus Moore (2-1) S: John Wetteland (35) | Seventh | 36½ out |
| » Major-league debuts: Charlie Montoyo (Expos) |
| Wednesday, September 8 |
| » Lost to Expos (79-61), 6-1 | Stade Olympique (1-5) | 53-87 | Lost 3 |
| » W: Kirk Rueter (7-0) L: Armando Reynoso (9-10) S: Tim Scott (1) | Seventh | 37 out |
| Thursday, September 9 |
| » Defeated Pirates (64-76), 10-7 | Three Rivers Stadium (2-1) | 54-87 | |
| » W: Gary Wayne (5-3) L: Joel Johnston (2-3) | Seventh | 36 out |
| » Major-league debuts: Rich Aude and Dan Miceli (Pirates) |
| Friday, September 10 |
| » Defeated Pirates (64-77), 9-8 | Three Rivers Stadium (3-1) | 55-87 | Won 2 |
| » W: Marcus Moore (3-1) L: Blas Minor (7-6) S: Darren Holmes (21) | Sixth | 35 out |
| » Major-league debuts: Midre Cummings and Tony Womack (Pirates) |
| Saturday, September 11 |
| » Defeated Pirates (64-78), 3-2 | Three Rivers Stadium (4-1) | 56-87 | Won 3 |
| » W: Kent Bottenfield (5-10) L: Tim Wakefield (4-10) S: Bruce Ruffin (1) | Sixth | 35 out |
| Sunday, September 12 |
| » Lost to Pirates (65-78), 4-3 | Three Rivers Stadium (4-2) | 56-88 | |
| » W: Tony Menendez (2-0) L: Mike Munoz (1-2) | Sixth | 35 out |
| Tuesday, September 14 |
| » Defeated Astros (76-67), 9-4 | Mile High Stadium (30-39) | 57-88 | |
| » W: Armando Reynoso (10-10) L: Doug Drabek (8-16) S: Bruce Ruffin (2) | Sixth | 34½ out |
| » Defeated Astros (76-68), 6-5 | Mile High Stadium (31-39) | 58-88 | Won 2 |
| » W: Darren Holmes (3-3) L: Xavier Hernandez (3-5) | Sixth | 34½ out |
| Wednesday, September 15 |
| » Defeated Astros (76-69), 6-4 | Mile High Stadium (32-39) | 59-88 | Won 3 |
| » W: Mike Munoz (2-2) L: Brian Williams (4-4) S: Darren Holmes (22) | Sixth | 34½ out |
| Thursday, September 16 |
| » Defeated Astros (76-70), 6-3 | Mile High Stadium (33-39) | 60-88 | Won 4 |
| » W: Bruce Ruffin (6-5) L: Todd Jones (1-2) S: Darren Holmes (23) | Sixth | 34½ out |
| Friday, September 17 |
| » Defeated Dodgers (74-72), 12-3 | Mile High Stadium (34-39) | 61-88 | Won 5 |
| » W: David Nied (4-7) L: Tom Candiotti (8-8) | Sixth | 34½ out |
|