| Tuesday, April 6 |
| » Lost to Pirates (1-0), 9-4 | Three Rivers Stadium (0-1) | 0-1 | |
| » W: Tim Wakefield (1-0) L: Andy Benes (0-1) S: John Candelaria (1) | Third | 1 out |
| » Major-league debuts: Pat Gomez (Padres) |
| Wednesday, April 7 |
| » Major-league debuts: Mike Mohler (Athletics) Greg Gohr (Tigers) |
| Thursday, April 8 |
| » Lost to Pirates (2-0), 5-4 | Three Rivers Stadium (0-2) | 0-2 | Lost 2 |
| » W: Bob Walk (1-0) L: Greg Harris (0-1) S: Stan Belinda (1) | Fourth | 2 out |
| » Major-league debuts: Darrell Sherman (Padres) |
| Friday, April 9 |
| » Defeated Marlins (1-3), 2-1 | Joe Robbie Stadium (1-0) | 1-2 | |
| » W: Gene Harris (1-0) L: Bryan Harvey (0-1) | Third | 2 out |
| Saturday, April 10 |
| » Lost to Marlins (2-3), 2-1 | Joe Robbie Stadium (1-1) | 1-3 | |
| » W: Charlie Hough (2-0) L: Dave Eiland (0-1) S: Bryan Harvey (2) | Fifth | 2 out |
| Sunday, April 11 |
| » Defeated Marlins (2-4), 6-2 | Joe Robbie Stadium (2-1) | 2-3 | |
| » W: Andy Benes (1-1) L: Jack Armstrong (0-2) S: Gene Harris (1) | Fourth | 2 out |
| Monday, April 12 |
| » Lost to Pirates (4-2), 4-2 | San Diego/Jack Murphy Stadium (0-1) | 2-4 | |
| » W: Dave Otto (1-0) L: Greg Harris (0-2) S: Stan Belinda (3) | Sixth | 2 out |
| Tuesday, April 13 |
| » Lost to Pirates (5-2), 6-4 | San Diego/Jack Murphy Stadium (0-2) | 2-5 | Lost 2 |
| » W: Bob Walk (2-0) L: Pat Gomez (0-1) S: Paul Wagner (1) | Sixth | 3 out |
| » Major-league debuts: Ricky Gutierrez and Kerry Taylor (Padres) |
| Wednesday, April 14 |
| » Lost to Pirates (6-2), 11-7 | San Diego/Jack Murphy Stadium (0-3) | 2-6 | Lost 3 |
| » W: Blas Minor (2-0) L: Frank Seminara (0-1) | Sixth | 3 out |
| Thursday, April 15 |
| » Lost to Pirates (7-2), 5-4 | San Diego/Jack Murphy Stadium (0-4) | 2-7 | Lost 4 |
| » W: Dennis Moeller (1-0) L: Jeremy Hernandez (0-1) S: Stan Belinda (4) | Sixth | 3½ out |
| Friday, April 16 |
| » Defeated Cardinals (7-3), 5-1 | San Diego/Jack Murphy Stadium (1-4) | 3-7 | |
| » W: Andy Benes (2-1) L: Joe Magrane (0-1) | Sixth | 3½ out |
| Saturday, April 17 |
| » Defeated Cardinals (7-4), 2-1 | San Diego/Jack Murphy Stadium (2-4) | 4-7 | Won 2 |
| » W: Greg Harris (1-2) L: Rheal Cormier (1-1) S: Gene Harris (2) | Sixth | 2½ out |
| Sunday, April 18 |
| » Defeated Cardinals (7-5), 10-6 | San Diego/Jack Murphy Stadium (3-4) | 5-7 | Won 3 |
| » W: Tim Scott (1-0) L: Mike Perez (1-1) S: Rich Rodriguez (1) | Fifth | 2½ out |
| Tuesday, April 20 |
| » Lost to Phillies (10-3), 4-3 | Veteran's Stadium (0-1) | 5-8 | |
| » W: Bob Ayrault (1-0) L: Jeremy Hernandez (0-2) | Fifth | 3½ out |
| Thursday, April 22 |
| » Defeated Phillies (10-4), 2-1 | Veteran's Stadium (1-1) | 6-8 | |
| » W: Andy Benes (3-1) L: Terry Mulholland (2-2) S: Rich Rodriguez (2) | Fourth | 3 out |
| Friday, April 23 |
| » Lost to Mets (8-7), 6-1 | Shea Stadium (0-1) | 6-9 | |
| » W: Frank Tanana (2-0) L: Greg Harris (1-3) | Fourth | 3 out |
| Saturday, April 24 |
| » Defeated Mets (8-8), 5-3 | Shea Stadium (1-1) | 7-9 | |
| » W: Frank Seminara (1-1) L: Bret Saberhagen (2-2) S: Gene Harris (3) | Fourth | 3 out |
| Sunday, April 25 |
| » Defeated Mets (8-9), 9-8 | Shea Stadium (2-1) | 8-9 | Won 2 |
| » W: Tim Scott (2-0) L: Anthony Young (0-2) S: Gene Harris (4) | Fourth | 2 out |
| Monday, April 26 |
| » Lost to Expos (12-7), 6-4 | San Diego/Jack Murphy Stadium (3-5) | 8-10 | |
| » W: Jimmy Jones (4-0) L: Kerry Taylor (0-1) S: John Wetteland (1) | Fourth | 2 out |
| Tuesday, April 27 |
| » Defeated Expos (12-8), 4-1 | San Diego/Jack Murphy Stadium (4-5) | 9-10 | |
| » W: Andy Benes (4-1) L: Kent Bottenfield (1-2) | Fourth | 2 out |
| Wednesday, April 28 |
| » Lost to Phillies (15-5), 5-3 | San Diego/Jack Murphy Stadium (4-6) | 9-11 | |
| » W: Curt Schilling (4-1) L: Greg Harris (1-4) S: Mitch Williams (8) | Fourth | 3 out |
| Thursday, April 29 |
| » Lost to Phillies (16-5), 5-3 | San Diego/Jack Murphy Stadium (4-7) | 9-12 | Lost 2 |
| » W: Danny Jackson (2-0) L: Frank Seminara (1-2) S: Mitch Williams (9) | Fourth | 4 out |
| Friday, April 30 |
| » Defeated Mets (8-13), 7-6 | San Diego/Jack Murphy Stadium (5-7) | 10-12 | |
| » W: Rich Rodriguez (1-0) L: Anthony Young (0-3) S: Gene Harris (5) | Fourth | 4 out |
| Saturday, May 1 |
| » Defeated Mets (8-14), 5-3 | San Diego/Jack Murphy Stadium (6-7) | 11-12 | Won 2 |
| » W: Gene Harris (2-0) L: Mike Maddux (0-2) | Third | 4 out |
| Sunday, May 2 |
| » Lost to Mets (9-14), 3-2 | San Diego/Jack Murphy Stadium (6-8) | 11-13 | |
| » W: Dwight Gooden (3-3) L: Andy Benes (4-2) | Fourth | 5 out |
| Tuesday, May 4 |
| » Lost to Expos (14-12), 6-1 | Stade Olympique (0-1) | 11-14 | Lost 2 |
| » W: Dennis Martinez (2-4) L: Greg Harris (1-5) | Fourth | 5 out |
| Wednesday, May 5 |
| » Lost to Expos (15-12), 6-5 | Stade Olympique (0-2) | 11-15 | Lost 3 |
| » W: John Wetteland (1-0) L: Rich Rodriguez (1-1) | Fourth | 6 out |
| Friday, May 7 |
| » Defeated Cubs (13-14), 2-1 | Wrigley Field (1-0) | 12-15 | |
| » W: Andy Benes (5-2) L: Mike Morgan (2-5) S: Gene Harris (6) | Fourth | 6 out |
| Saturday, May 8 |
| » Lost to Cubs (14-14), 8-6 | Wrigley Field (1-1) | 12-16 | |
| » W: Chuck McElroy (2-1) L: Pat Gomez (0-2) S: Randy Myers (9) | Fourth | 6 out |
| Sunday, May 9 |
| » Defeated Cubs (14-15), 5-4 | Wrigley Field (2-1) | 13-16 | |
| » W: Greg Harris (2-5) L: Jose Guzman (3-3) S: Gene Harris (7) | Fourth | 5 out |
| Monday, May 10 |
| » Lost to Reds (13-18), 6-5 | Riverfront Stadium (0-1) | 13-17 | |
| » W: Tom Browning (3-2) L: Kerry Taylor (0-2) S: Jeff Reardon (5) | Fourth | 5½ out |
| Tuesday, May 11 |
| » Lost to Reds (14-18), 4-2 | Riverfront Stadium (0-2) | 13-18 | Lost 2 |
| » W: Milt Hill (2-0) L: Wally Whitehurst (0-1) S: Greg Cadaret (1) | Fifth | 6 out |
| Wednesday, May 12 |
| » Lost to Reds (15-18), 3-2 | Riverfront Stadium (0-3) | 13-19 | Lost 3 |
| » W: Jose Rijo (5-1) L: Andy Benes (5-3) | Sixth | 7 out |
| Thursday, May 13 |
| » Lost to Reds (16-18), 7-1 | Riverfront Stadium (0-4) | 13-20 | Lost 4 |
| » W: John Smiley (1-5) L: Dave Eiland (0-2) | Sixth | 8 out |
| Friday, May 14 |
| » Defeated Giants (22-14), 3-1 | San Diego/Jack Murphy Stadium (7-8) | 14-20 | |
| » W: Greg Harris (3-5) L: Jeff Brantley (2-3) | Fifth | 7 out |
| Saturday, May 15 |
| » Lost to Giants (23-14), 3-0 | San Diego/Jack Murphy Stadium (7-9) | 14-21 | |
| » W: Trevor Wilson (1-3) L: Kerry Taylor (0-3) S: Rod Beck (9) | Fifth | 8 out |
| Sunday, May 16 |
| » Lost to Giants (24-14), 9-4 | San Diego/Jack Murphy Stadium (7-10) | 14-22 | Lost 2 |
| » W: Bill Swift (5-1) L: Wally Whitehurst (0-2) | Fifth | 9 out |
| Monday, May 17 |
| » Defeated Rockies (11-27), 4-0 | San Diego/Jack Murphy Stadium (8-10) | 15-22 | |
| » W: Andy Benes (6-3) L: Butch Henry (2-4) | Fifth | 9 out |
| Tuesday, May 18 |
| » Lost to Rockies (12-27), 2-1 | San Diego/Jack Murphy Stadium (8-11) | 15-23 | |
| » W: Gary Wayne (1-2) L: Rich Rodriguez (1-2) S: Darren Holmes (3) | Sixth | 10 out |
| Wednesday, May 19 |
| » Defeated Rockies (12-28), 7-3 | San Diego/Jack Murphy Stadium (9-11) | 16-23 | |
| » W: Greg Harris (4-5) L: Lance Painter (0-1) | Sixth | 10 out |
| » Major-league debuts: Lance Painter (Rockies) |
| Thursday, May 20 |
| » Defeated Rockies (12-29), 5-4 | San Diego/Jack Murphy Stadium (10-11) | 17-23 | Won 2 |
| » W: Gene Harris (3-0) L: Darren Holmes (0-3) | Sixth | 10 out |
| Friday, May 21 |
| » Defeated Astros (22-18), 3-2 | San Diego/Jack Murphy Stadium (11-11) | 18-23 | Won 3 |
| » W: Rich Rodriguez (2-2) L: Doug Jones (1-3) | Sixth | 10 out |
| Saturday, May 22 |
| » Defeated Astros (22-19), 9-4 | San Diego/Jack Murphy Stadium (12-11) | 19-23 | Won 4 |
| » W: Andy Benes (7-3) L: Doug Drabek (4-5) | Sixth | 9 out |
| Sunday, May 23 |
| » Lost to Astros (23-19), 9-7 | San Diego/Jack Murphy Stadium (12-12) | 19-24 | |
| » W: Greg Swindell (5-4) L: Dave Eiland (0-3) S: Doug Jones (9) | Sixth | 10 out |
| Monday, May 24 |
| » Lost to Dodgers (21-22), 5-4 | Dodger Stadium (0-1) | 19-25 | Lost 2 |
| » W: Kevin Gross (4-3) L: Greg Harris (4-6) S: Pedro Martinez (1) | Sixth | 10½ out |
| Tuesday, May 25 |
| » Lost to Dodgers (22-22), 10-9 | Dodger Stadium (0-2) | 19-26 | Lost 3 |
| » W: Pedro Martinez (2-2) L: Roger Mason (0-1) | Sixth | 11½ out |
| Wednesday, May 26 |
| » Lost to Dodgers (23-22), 8-3 | Dodger Stadium (0-3) | 19-27 | Lost 4 |
| » W: Steve Wilson (1-0) L: Wally Whitehurst (0-3) | Sixth | 11½ out |
| Friday, May 28 |
| » Lost to Cardinals (24-22), 3-2 | Busch Stadium II (0-1) | 19-28 | Lost 5 |
| » W: Mike Perez (4-2) L: Rich Rodriguez (2-3) S: Lee Smith (14) | Fifth | 11 out |
| Saturday, May 29 |
| » Defeated Cardinals (24-23), 7-4 | Busch Stadium II (1-1) | 20-28 | |
| » W: Greg Harris (5-6) L: Omar Olivares (1-2) S: Gene Harris (8) | Fifth | 11 out |
| » Major-league debuts: Kevin Higgins (Padres) |
| Sunday, May 30 |
| » Lost to Cardinals (25-23), 10-4 | Busch Stadium II (1-2) | 20-29 | |
| » W: Rene Arocha (4-0) L: Kerry Taylor (0-4) | Sixth | 12 out |
| Monday, May 31 |
| » Lost to Braves (29-23), 2-1 | Atlanta-Fulton County Stadium (0-1) | 20-30 | Lost 2 |
| » W: Greg Maddux (5-4) L: Roger Mason (0-2) | Sixth | 12½ out |
| Tuesday, June 1 |
| » Defeated Braves (29-24), 2-1 | Atlanta-Fulton County Stadium (1-1) | 21-30 | |
| » W: Doug Brocail (1-0) L: John Smoltz (4-5) S: Gene Harris (9) | Fifth | 12 out |
| Wednesday, June 2 |
| » Lost to Braves (30-24), 5-2 | Atlanta-Fulton County Stadium (1-2) | 21-31 | |
| » W: Steve Avery (6-2) L: Andy Benes (7-4) S: Mike Stanton (19) | Sixth | 13 out |
| Thursday, June 3 |
| » Defeated Braves (30-25), 12-4 | Atlanta-Fulton County Stadium (2-2) | 22-31 | |
| » W: Greg Harris (6-6) L: Pete Smith (2-5) | Sixth | 12 out |
| Friday, June 4 |
| » Lost to Marlins (23-30), 6-2 | San Diego/Jack Murphy Stadium (12-13) | 22-32 | |
| » W: Charlie Hough (3-6) L: Bruce Hurst (0-1) | Sixth | 12 out |
| Saturday, June 5 |
| » Lost to Marlins (24-30), 3-1 | San Diego/Jack Murphy Stadium (12-14) | 22-33 | Lost 2 |
| » W: Luis Aquino (3-3) L: Roger Mason (0-3) S: Bryan Harvey (16) | Sixth | 13 out |
| » Major-league debuts: Mark Ettles (Padres) |
| Sunday, June 6 |
| » Lost to Marlins (25-30), 9-2 | San Diego/Jack Murphy Stadium (12-15) | 22-34 | Lost 3 |
| » W: Chris Hammond (5-4) L: Doug Brocail (1-1) | Sixth | 14 out |
| Monday, June 7 |
| » Lost to Braves (32-27), 4-0 | San Diego/Jack Murphy Stadium (12-16) | 22-35 | Lost 4 |
| » W: Steve Avery (7-2) L: Andy Benes (7-5) | Sixth | 14½ out |
| Tuesday, June 8 |
| » Defeated Braves (32-28), 5-4 | San Diego/Jack Murphy Stadium (13-16) | 23-35 | |
| » W: Gene Harris (4-0) L: Mike Stanton (1-2) | Sixth | 13½ out |
| Thursday, June 10 |
| » Defeated Dodgers (30-27), 14-2 | San Diego/Jack Murphy Stadium (14-16) | 24-35 | Won 2 |
| » W: Wally Whitehurst (1-3) L: Ramon Martinez (5-4) | Sixth | 13½ out |
| Friday, June 11 |
| » Defeated Dodgers (30-28), 5-4 | San Diego/Jack Murphy Stadium (15-16) | 25-35 | Won 3 |
| » W: Pat Gomez (1-2) L: Jim Gott (2-2) | Sixth | 13½ out |
| Saturday, June 12 |
| » Lost to Dodgers (31-28), 6-4 | San Diego/Jack Murphy Stadium (15-17) | 25-36 | |
| » W: Omar Daal (1-1) L: Roger Mason (0-4) S: Jim Gott (9) | Sixth | 14½ out |
| Sunday, June 13 |
| » Lost to Dodgers (32-28), 2-1 | San Diego/Jack Murphy Stadium (15-18) | 25-37 | Lost 2 |
| » W: Orel Hershiser (6-4) L: Greg Harris (6-7) S: Jim Gott (10) | Fifth | 15½ out |
| Tuesday, June 15 |
| » Defeated Astros (32-29), 3-0 | Astrodome (1-0) | 26-37 | |
| » W: Wally Whitehurst (2-3) L: Pete Harnisch (6-4) S: Gene Harris (10) | Sixth | 14½ out |
| Wednesday, June 16 |
| » Lost to Astros (33-29), 5-4 | Astrodome (1-1) | 26-38 | |
| » W: Mark Portugal (5-2) L: Doug Brocail (1-2) S: Al Osuna (1) | Sixth | 15½ out |
| Thursday, June 17 |
| » Lost to Astros (34-29), 4-1 | Astrodome (1-2) | 26-39 | Lost 2 |
| » W: Darryl Kile (6-1) L: Andy Benes (7-6) S: Brian Williams (2) | Fifth | 16½ out |
| Friday, June 18 |
| » Defeated Rockies (21-44), 11-1 | Mile High Stadium (1-0) | 27-39 | |
| » W: Greg Harris (7-7) L: Bruce Ruffin (3-3) | Fifth | 16½ out |
| Saturday, June 19 |
| » Lost to Rockies (22-44), 17-3 | Mile High Stadium (1-1) | 27-40 | |
| » W: Willie Blair (3-4) L: Kerry Taylor (0-5) | Fifth | 17½ out |
| Sunday, June 20 |
| » Lost to Rockies (23-44), 3-1 | Mile High Stadium (1-2) | 27-41 | Lost 2 |
| » W: Steve Reed (2-2) L: Roger Mason (0-5) S: Darren Holmes (5) | Sixth | 18½ out |
| Monday, June 21 |
| » Lost to Giants (47-23), 2-1 | Candlestick Park (0-1) | 27-42 | Lost 3 |
| » W: Trevor Wilson (5-3) L: Doug Brocail (1-3) S: Rod Beck (22) | Sixth | 19½ out |
| Tuesday, June 22 |
| » Defeated Giants (47-24), 2-1 | Candlestick Park (1-1) | 28-42 | |
| » W: Andy Benes (8-6) L: Bill Swift (9-4) S: Gene Harris (11) | Sixth | 18½ out |
| Wednesday, June 23 |
| » Lost to Giants (48-24), 6-2 | Candlestick Park (1-2) | 28-43 | |
| » W: Bud Black (7-1) L: Greg Harris (7-8) | Fifth | 19½ out |
| Thursday, June 24 |
| » Lost to Reds (34-39), 6-4 | San Diego/Jack Murphy Stadium (15-19) | 28-44 | Lost 2 |
| » W: Bobby Ayala (3-3) L: Roger Mason (0-6) S: Rob Dibble (7) | Sixth | 20½ out |
| Friday, June 25 |
| » Lost to Reds (35-39), 6-2 | San Diego/Jack Murphy Stadium (15-20) | 28-45 | Lost 3 |
| » W: Tim Belcher (6-5) L: Wally Whitehurst (2-4) | Sixth | 21½ out |
| » Major-league debuts: Tim Worrell (Padres) |
| Saturday, June 26 |
| » Defeated Reds (35-40), 2-0 | San Diego/Jack Murphy Stadium (16-20) | 29-45 | |
| » W: Doug Brocail (2-3) L: Jose Rijo (6-3) S: Gene Harris (12) | Fifth | 20½ out |
| Sunday, June 27 |
| » Lost to Reds (36-40), 7-1 | San Diego/Jack Murphy Stadium (16-21) | 29-46 | |
| » W: Rob Dibble (1-0) L: Gene Harris (4-1) | Fifth | 21½ out |
| Monday, June 28 |
| » Lost to Cubs (35-38), 4-3 | San Diego/Jack Murphy Stadium (16-22) | 29-47 | Lost 2 |
| » W: Paul Assenmacher (2-1) L: Roger Mason (0-7) S: Randy Myers (23) | Sixth | 21½ out |
| Tuesday, June 29 |
| » Lost to Cubs (36-38), 10-5 | San Diego/Jack Murphy Stadium (16-23) | 29-48 | Lost 3 |
| » W: Mike Morgan (5-8) L: Tim Worrell (0-1) | Sixth | 22½ out |
| » Major-league debuts: Pedro Martinez (Padres) |
| Wednesday, June 30 |
| » Lost to Cubs (37-38), 4-1 | San Diego/Jack Murphy Stadium (16-24) | 29-49 | Lost 4 |
| » W: Jose Guzman (7-6) L: Wally Whitehurst (2-5) S: Randy Myers (24) | Sixth | 22½ out |
| Friday, July 2 |
| » Defeated Phillies (52-27), 5-2 | Veteran's Stadium (2-1) | 30-49 | |
| » W: Mark Ettles (1-0) L: Terry Mulholland (9-6) S: Gene Harris (13) | Sixth | 23 out |
| » Lost to Phillies (53-27), 6-5 | Veteran's Stadium (2-2) | 30-50 | |
| » W: Mitch Williams (2-3) L: Trevor Hoffman (2-3) | Sixth | 23 out |
| Saturday, July 3 |
| » Defeated Phillies (53-28), 6-4 | Veteran's Stadium (3-2) | 31-50 | |
| » W: Greg Harris (8-8) L: Danny Jackson (7-5) S: Gene Harris (14) | Fifth | 22 out |
| Sunday, July 4 |
| » Lost to Phillies (54-28), 8-4 | Veteran's Stadium (3-3) | 31-51 | |
| » W: Ben Rivera (9-3) L: Tim Worrell (0-2) | Fifth | 23 out |
| Monday, July 5 |
| » Defeated Mets (24-56), 12-7 | Shea Stadium (3-1) | 32-51 | |
| » W: Wally Whitehurst (3-5) L: Pete Schourek (2-10) | Fifth | 23 out |
| Tuesday, July 6 |
| » Lost to Mets (25-56), 9-7 | Shea Stadium (3-2) | 32-52 | |
| » W: Dwight Gooden (8-8) L: Doug Brocail (2-4) | Sixth | 24 out |
| Wednesday, July 7 |
| » Defeated Mets (25-57), 2-0 | Shea Stadium (4-2) | 33-52 | |
| » W: Andy Benes (9-6) L: Anthony Young (0-12) S: Gene Harris (15) | Sixth | 23 out |
| Thursday, July 8 |
| » Lost to Expos (45-40), 5-4 | Stade Olympique (0-3) | 33-53 | |
| » W: Dennis Martinez (10-5) L: Greg Harris (8-9) S: John Wetteland (20) | Sixth | 24 out |
| Friday, July 9 |
| » Lost to Expos (46-40), 6-1 | Stade Olympique (0-4) | 33-54 | Lost 2 |
| » W: Chris Nabholz (5-5) L: Tim Worrell (0-3) | Sixth | 25 out |
| Saturday, July 10 |
| » Lost to Expos (47-40), 3-2 | Stade Olympique (0-5) | 33-55 | Lost 3 |
| » W: Pete Young (1-0) L: Gene Harris (4-2) | Fifth | 25 out |
| Sunday, July 11 |
| » Lost to Expos (48-40), 5-4 | Stade Olympique (0-6) | 33-56 | Lost 4 |
| » W: John Wetteland (4-0) L: Gene Harris (4-3) S: Dennis Martinez (1) | Sixth | 26 out |
| Thursday, July 15 |
| » Defeated Phillies (57-33), 5-2 | San Diego/Jack Murphy Stadium (17-24) | 34-56 | |
| » W: Greg Harris (9-9) L: Danny Jackson (7-7) S: Mark Davis (1) | Sixth | 26 out |
| Friday, July 16 |
| » Defeated Phillies (57-34), 5-3 | San Diego/Jack Murphy Stadium (18-24) | 35-56 | Won 2 |
| » W: Pedro Martinez (1-0) L: Tommy Greene (11-3) S: Mark Davis (2) | Sixth | 26 out |
| Saturday, July 17 |
| » Defeated Phillies (57-35), 4-2 | San Diego/Jack Murphy Stadium (19-24) | 36-56 | Won 3 |
| » W: Andy Benes (10-6) L: Terry Mulholland (9-7) S: Gene Harris (16) | Sixth | 25 out |
| Sunday, July 18 |
| » Lost to Phillies (58-35), 6-3 | San Diego/Jack Murphy Stadium (19-25) | 36-57 | |
| » W: Curt Schilling (9-6) L: Doug Brocail (2-5) S: Mitch Williams (24) | Sixth | 25 out |
| Monday, July 19 |
| » Lost to Mets (30-62), 2-1 | San Diego/Jack Murphy Stadium (19-26) | 36-58 | Lost 2 |
| » W: John Franco (3-0) L: Gene Harris (4-4) | Sixth | 26 out |
| Tuesday, July 20 |
| » Defeated Mets (30-63), 4-1 | San Diego/Jack Murphy Stadium (20-26) | 37-58 | |
| » W: Greg Harris (10-9) L: Dave Telgheder (3-2) | Sixth | 26 out |
| Wednesday, July 21 |
| » Lost to Mets (31-63), 5-2 | San Diego/Jack Murphy Stadium (20-27) | 37-59 | |
| » W: Dwight Gooden (9-10) L: Wally Whitehurst (3-6) S: John Franco (6) | Fifth | 27 out |
| Thursday, July 22 |
| » Lost to Expos (50-46), 10-5 | San Diego/Jack Murphy Stadium (20-28) | 37-60 | Lost 2 |
| » W: Ken Hill (7-2) L: Andy Benes (10-7) | Sixth | 28 out |
| » Major-league debuts: Derrick White (Expos) |
| Friday, July 23 |
| » Lost to Expos (51-46), 5-0 | San Diego/Jack Murphy Stadium (20-29) | 37-61 | Lost 3 |
| » W: Jeff Fassero (6-1) L: Doug Brocail (2-6) S: Mel Rojas (7) | Sixth | 28 out |
| Saturday, July 24 |
| » Defeated Expos (51-47), 11-4 | San Diego/Jack Murphy Stadium (21-29) | 38-61 | |
| » W: Tim Worrell (1-3) L: Chris Nabholz (5-7) | Fifth | 28 out |
| Sunday, July 25 |
| » Lost to Expos (52-47), 5-4 | San Diego/Jack Murphy Stadium (21-30) | 38-62 | |
| » W: John Wetteland (5-1) L: Gene Harris (4-5) S: Mel Rojas (8) | Fifth | 29 out |
| Monday, July 26 |
| » Lost to Cubs (50-48), 9-6 | Wrigley Field (2-2) | 38-63 | Lost 2 |
| » W: Shawn Boskie (2-1) L: Tim Mauser (0-1) | Sixth | 29 out |
| Tuesday, July 27 |
| » Defeated Cubs (50-49), 8-0 | Wrigley Field (3-2) | 39-63 | |
| » W: Andy Benes (11-7) L: Mike Harkey (7-5) | Fifth | 29 out |
| Wednesday, July 28 |
| » Lost to Cubs (51-49), 8-6 | Wrigley Field (3-3) | 39-64 | |
| » W: Shawn Boskie (3-1) L: Doug Brocail (2-7) S: Randy Myers (31) | Fifth | 29 out |
| » Major-league debuts: Brad Ausmus (Padres) |
| Friday, July 30 |
| » Defeated Reds (52-53), 11-9 | Riverfront Stadium (1-4) | 40-64 | |
| » W: Trevor Hoffman (3-3) L: Jeff Reardon (2-4) S: Mark Davis (3) | Sixth | 29 out |
| Saturday, July 31 |
| » Lost to Reds (53-53), 6-3 | Riverfront Stadium (1-5) | 40-65 | |
| » W: Jose Rijo (9-5) L: Andy Ashby (0-5) S: Rob Dibble (15) | Sixth | 30 out |
| Sunday, August 1 |
| » Defeated Reds (53-54), 3-1 | Riverfront Stadium (2-5) | 41-65 | |
| » W: Andy Benes (12-7) L: Tom Browning (7-7) S: Gene Harris (17) | Sixth | 30 out |
| » Major-league debuts: Greg Tubbs (Reds) |
| Tuesday, August 3 |
| » Lost to Giants (72-35), 12-7 | San Diego/Jack Murphy Stadium (21-31) | 41-66 | |
| » W: Dave Burba (9-2) L: Mark Davis (1-3) | Sixth | 31 out |
| Wednesday, August 4 |
| » Defeated Giants (72-36), 11-10 | San Diego/Jack Murphy Stadium (22-31) | 42-66 | |
| » W: Pedro Martinez (2-0) L: Bryan Hickerson (5-3) | Sixth | 30 out |
| Thursday, August 5 |
| » Lost to Giants (73-36), 5-3 | San Diego/Jack Murphy Stadium (22-32) | 42-67 | |
| » W: Bill Swift (16-5) L: Andy Ashby (0-6) S: Rod Beck (32) | Sixth | 31 out |
| Friday, August 6 |
| » Defeated Rockies (36-73), 6-3 | San Diego/Jack Murphy Stadium (23-32) | 43-67 | |
| » W: Andy Benes (13-7) L: Armando Reynoso (7-8) S: Trevor Hoffman (3) | Sixth | 30½ out |
| » Defeated Rockies (36-74), 6-2 | San Diego/Jack Murphy Stadium (24-32) | 44-67 | Won 2 |
| » W: Scott Sanders (1-0) L: Willie Blair (4-9) | Sixth | 30½ out |
| » Major-league debuts: Scott Sanders (Padres) |
| Former Padre Bob Miller dies in Rancho Bernardo, CA at the age of 55. |
| Sunday, August 8 |
| » Lost to Rockies (37-74), 5-2 | San Diego/Jack Murphy Stadium (24-33) | 44-68 | |
| » W: Mo Sanford (1-0) L: Doug Brocail (2-8) S: Darren Holmes (11) | Sixth | 30 out |
| Monday, August 9 |
| » Lost to Astros (58-54), 5-4 | San Diego/Jack Murphy Stadium (24-34) | 44-69 | Lost 2 |
| » W: Xavier Hernandez (3-2) L: Trevor Hoffman (3-4) S: Doug Jones (21) | Sixth | 31 out |
| Tuesday, August 10 |
| » Defeated Astros (58-55), 7-2 | San Diego/Jack Murphy Stadium (25-34) | 45-69 | |
| » W: Andy Ashby (1-6) L: Doug Drabek (7-14) | Sixth | 31 out |
| Wednesday, August 11 |
| » Lost to Astros (59-55), 9-6 | San Diego/Jack Murphy Stadium (25-35) | 45-70 | |
| » W: Darryl Kile (12-4) L: Andy Benes (13-8) S: Doug Jones (22) | Sixth | 32 out |
| Thursday, August 12 |
| » Lost to Astros (60-55), 5-3 | San Diego/Jack Murphy Stadium (25-36) | 45-71 | Lost 2 |
| » W: Greg Swindell (8-9) L: Trevor Hoffman (3-5) S: Doug Jones (23) | Sixth | 32½ out |
| Friday, August 13 |
| » Defeated Dodgers (57-58), 4-1 | Dodger Stadium (1-3) | 46-71 | |
| » W: Wally Whitehurst (4-6) L: Kevin Gross (7-11) S: Gene Harris (18) | Sixth | 32½ out |
| Saturday, August 14 |
| » Lost to Dodgers (58-58), 4-3 | Dodger Stadium (1-4) | 46-72 | |
| » W: Tom Candiotti (8-5) L: Doug Brocail (2-9) S: Jim Gott (21) | Sixth | 32½ out |
| Sunday, August 15 |
| » Lost to Dodgers (59-58), 4-2 | Dodger Stadium (1-5) | 46-73 | Lost 2 |
| » W: Pedro Astacio (9-7) L: Andy Ashby (1-7) S: Jim Gott (22) | Sixth | 33½ out |
| Tuesday, August 17 |
| » Lost to Cardinals (67-52), 8-4 | Busch Stadium II (1-3) | 46-74 | Lost 3 |
| » W: Bob Tewksbury (13-7) L: Andy Benes (13-9) | Sixth | 33½ out |
| Wednesday, August 18 |
| » Lost to Cardinals (68-52), 4-0 | Busch Stadium II (1-4) | 46-75 | Lost 4 |
| » W: Donovan Osborne (10-6) L: Doug Brocail (2-10) S: Rob Murphy (1) | Sixth | 34½ out |
| Thursday, August 19 |
| » Lost to Cardinals (69-52), 3-2 | Busch Stadium II (1-5) | 46-76 | Lost 5 |
| » W: Mike Perez (5-2) L: Mark Davis (1-4) S: Lee Smith (41) | Sixth | 35½ out |
| Friday, August 20 |
| » Lost to Pirates (58-65), 7-6 | San Diego/Jack Murphy Stadium (25-37) | 46-77 | Lost 6 |
| » W: Mark Petkovsek (3-0) L: Mark Davis (1-5) S: Mark Dewey (3) | Sixth | 35½ out |
| Sunday, August 22 |
| » Lost to Pirates (59-65), 10-5 | San Diego/Jack Murphy Stadium (25-38) | 46-78 | Lost 7 |
| » W: Steve Cooke (8-7) L: Andy Benes (13-10) | Seventh | 37 out |
| Monday, August 23 |
| » Defeated Cardinals (69-56), 7-5 | San Diego/Jack Murphy Stadium (26-38) | 47-78 | |
| » W: Pedro Martinez (3-0) L: Donovan Osborne (10-7) S: Gene Harris (19) | Seventh | 36 out |
| Tuesday, August 24 |
| » Defeated Cardinals (69-57), 17-4 | San Diego/Jack Murphy Stadium (27-38) | 48-78 | Won 2 |
| » W: Andy Ashby (2-7) L: Allen Watson (6-1) | Sixth | 35 out |
| Wednesday, August 25 |
| » Defeated Cardinals (69-58), 2-1 | San Diego/Jack Murphy Stadium (28-38) | 49-78 | Won 3 |
| » W: Gene Harris (5-5) L: Lee Guetterman (2-3) | Sixth | 34 out |
| Friday, August 27 |
| » Defeated Pirates (60-68), 10-6 | Three Rivers Stadium (1-2) | 50-78 | Won 4 |
| » W: Andy Benes (14-10) L: Steve Cooke (8-8) S: Trevor Hoffman (4) | Sixth | 33 out |
| Saturday, August 28 |
| » Defeated Pirates (60-69), 5-3 | Three Rivers Stadium (2-2) | 51-78 | Won 5 |
| » W: Scott Sanders (2-0) L: Zane Smith (3-7) S: Gene Harris (20) | Sixth | 32½ out |
| Sunday, August 29 |
| » Lost to Pirates (61-69), 7-4 | Three Rivers Stadium (2-3) | 51-79 | |
| » W: Bob Walk (12-12) L: Andy Ashby (2-8) S: Mark Dewey (4) | Sixth | 33 out |
| » Defeated Pirates (61-70), 11-0 | Three Rivers Stadium (3-3) | 52-79 | |
| » W: Doug Brocail (3-10) L: John Hope (0-1) | Sixth | 33 out |
| » Major-league debuts: John Hope (Pirates) |
| Tuesday, August 31 |
| » Lost to Marlins (55-76), 2-1 | Joe Robbie Stadium (2-2) | 52-80 | |
| » W: Charlie Hough (8-14) L: Tim Worrell (1-4) S: Bryan Harvey (39) | Sixth | 33½ out |
| Wednesday, September 1 |
| » Defeated Marlins (55-77), 13-5 | Joe Robbie Stadium (3-2) | 53-80 | |
| » W: Andy Benes (15-10) L: Ryan Bowen (8-12) | Sixth | 33½ out |
| Thursday, September 2 |
| » Lost to Marlins (56-77), 8-2 | Joe Robbie Stadium (3-3) | 53-81 | |
| » W: Pat Rapp (3-4) L: Scott Sanders (2-1) | Sixth | 33½ out |
| Friday, September 3 |
| » Lost to Braves (84-51), 7-3 | Atlanta-Fulton County Stadium (2-3) | 53-82 | Lost 2 |
| » W: Tom Glavine (17-5) L: Andy Ashby (2-9) | Sixth | 34½ out |
| Saturday, September 4 |
| » Lost to Braves (85-51), 3-2 | Atlanta-Fulton County Stadium (2-4) | 53-83 | Lost 3 |
| » W: Kent Mercker (3-1) L: Doug Brocail (3-11) S: Greg McMichael (13) | Sixth | 35½ out |
| Sunday, September 5 |
| » Lost to Braves (86-51), 3-2 | Atlanta-Fulton County Stadium (2-5) | 53-84 | Lost 4 |
| » W: Greg Maddux (17-9) L: Pedro Martinez (3-1) | Sixth | 35½ out |
| Monday, September 6 |
| » Lost to Marlins (58-79), 2-0 | San Diego/Jack Murphy Stadium (28-39) | 53-85 | Lost 5 |
| » W: Dave Weathers (1-0) L: Andy Benes (15-11) S: Bryan Harvey (41) | Sixth | 36½ out |
| Tuesday, September 7 |
| » Defeated Marlins (58-80), 6-4 | San Diego/Jack Murphy Stadium (29-39) | 54-85 | |
| » W: Trevor Hoffman (4-5) L: Luis Aquino (6-8) S: Gene Harris (21) | Sixth | 35½ out |
| » Major-league debuts: Luis Lopez (Padres) |
| Wednesday, September 8 |
| » Defeated Marlins (58-81), 3-2 | San Diego/Jack Murphy Stadium (30-39) | 55-85 | Won 2 |
| » W: Frank Seminara (2-2) L: Chris Hammond (10-10) S: Gene Harris (22) | Sixth | 35 out |
| » Major-league debuts: Dave Staton (Padres) Nigel Wilson (Marlins) |
| Thursday, September 9 |
| » Lost to Braves (89-52), 1-0 | San Diego/Jack Murphy Stadium (30-40) | 55-86 | |
| » W: Greg McMichael (2-3) L: Trevor Hoffman (4-6) | Sixth | 35 out |
| » Major-league debuts: Ramon Caraballo (Braves) |
| Friday, September 10 |
| » Lost to Braves (90-52), 3-2 | San Diego/Jack Murphy Stadium (30-41) | 55-87 | Lost 2 |
| » W: Greg Maddux (18-9) L: Tim Worrell (1-5) S: Greg McMichael (15) | Sixth | 35 out |
| Saturday, September 11 |
| » Lost to Braves (91-52), 13-1 | San Diego/Jack Murphy Stadium (30-42) | 55-88 | Lost 3 |
| » W: John Smoltz (14-10) L: Andy Benes (15-12) | Seventh | 36 out |
| » Major-league debuts: Chipper Jones (Braves) |
| Sunday, September 12 |
| » Defeated Braves (91-53), 5-4 | San Diego/Jack Murphy Stadium (31-42) | 56-88 | |
| » W: Scott Sanders (3-1) L: Steve Avery (16-5) S: Gene Harris (23) | Sixth | 35 out |
| Monday, September 13 |
| » Defeated Dodgers (72-71), 4-3 | San Diego/Jack Murphy Stadium (32-42) | 57-88 | Won 2 |
| » W: Gene Harris (6-5) L: Jim Gott (4-8) | Sixth | 34½ out |
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