| Tuesday, April 6 |
| » Defeated Blue Jays (0-1), 8-1 | Kingdome (1-0) | 1-0 | |
| » W: Randy Johnson (1-0) L: Jack Morris (0-1) | First | -- |
| Wednesday, April 7 |
| » Lost to Blue Jays (1-1), 2-0 | Kingdome (1-1) | 1-1 | |
| » W: Al Leiter (1-0) L: Chris Bosio (0-1) S: Duane Ward (1) | Second | 1 out |
| Thursday, April 8 |
| » Major-league debuts: Brett Merriman (Twins) |
| Friday, April 9 |
| » Defeated Orioles (0-3), 6-0 | Kingdome (2-1) | 2-1 | |
| » W: Erik Hanson (1-0) L: Ben McDonald (0-1) | Second | 1 out |
| Saturday, April 10 |
| » Lost to Orioles (1-3), 5-3 | Kingdome (2-2) | 2-2 | |
| » W: Rick Sutcliffe (1-1) L: John Cummings (0-1) S: Gregg Olson (1) | Third | 1 out |
| » Major-league debuts: John Cummings and Fernando Vina (Mariners) Sherman Obando (Orioles) |
| Sunday, April 11 |
| » Defeated Orioles (1-4), 7-6 | Kingdome (3-2) | 3-2 | |
| » W: Russ Swan (1-0) L: Mark Williamson (0-1) | Third | 1 out |
| Tuesday, April 13 |
| » Lost to Blue Jays (4-2), 6-5 | Skydome (0-1) | 3-3 | |
| » W: Danny Cox (1-0) L: Tim Leary (0-1) S: Duane Ward (4) | Fourth | 2½ out |
| Wednesday, April 14 |
| » Defeated Blue Jays (4-3), 10-9 | Skydome (1-1) | 4-3 | |
| » W: Rich DeLucia (1-0) L: Pat Hentgen (0-1) S: Norm Charlton (1) | Third | 1½ out |
| Thursday, April 15 |
| » Lost to Blue Jays (5-3), 3-1 | Skydome (1-2) | 4-4 | |
| » W: Todd Stottlemyre (2-0) L: John Cummings (0-2) S: Duane Ward (5) | Third | 2 out |
| Friday, April 16 |
| » Lost to Tigers (5-4), 5-0 | Tiger Stadium (0-1) | 4-5 | Lost 2 |
| » W: David Wells (2-0) L: Randy Johnson (1-1) | Fifth | 2 out |
| Saturday, April 17 |
| » Lost to Tigers (6-4), 20-3 | Tiger Stadium (0-2) | 4-6 | Lost 3 |
| » W: Bill Krueger (1-1) L: Mike Hampton (0-1) | Sixth | 3 out |
| » Major-league debuts: Mike Hampton (Mariners) |
| Sunday, April 18 |
| » Lost to Tigers (7-4), 8-7 | Tiger Stadium (0-3) | 4-7 | Lost 4 |
| » W: Rob MacDonald (1-0) L: Norm Charlton (0-1) | Sixth | 4 out |
| Monday, April 19 |
| » Defeated Tigers (7-5), 10-6 | Tiger Stadium (1-3) | 5-7 | |
| » W: Erik Hanson (2-0) L: John Doherty (1-1) S: Dwayne Henry (1) | Fourth | 3½ out |
| Tuesday, April 20 |
| » Lost to Red Sox (11-3), 5-2 | Kingdome (3-3) | 5-8 | |
| » W: Roger Clemens (3-0) L: John Cummings (0-3) S: Jeff Russell (3) | Sixth | 3½ out |
| Wednesday, April 21 |
| » Defeated Red Sox (11-4), 5-0 | Kingdome (4-3) | 6-8 | |
| » W: Randy Johnson (2-1) L: Danny Darwin (0-3) | Fifth | 3 out |
| Thursday, April 22 |
| » Defeated Red Sox (11-5), 7-0 | Kingdome (5-3) | 7-8 | Won 2 |
| » W: Chris Bosio (1-1) L: Joe Hesketh (2-1) | Fifth | 3 out |
| Friday, April 23 |
| » Defeated Yankees (8-8), 6-3 | Kingdome (6-3) | 8-8 | Won 3 |
| » W: Mike Hampton (1-1) L: Jim Abbott (1-3) S: Norm Charlton (2) | Fourth | 3 out |
| Saturday, April 24 |
| » Lost to Yankees (9-8), 1-0 | Kingdome (6-4) | 8-9 | |
| » W: Steve Howe (1-0) L: Russ Swan (1-1) S: Steve Farr (3) | Fourth | 4 out |
| Sunday, April 25 |
| » Lost to Yankees (10-8), 10-9 | Kingdome (6-5) | 8-10 | Lost 2 |
| » W: Rich Monteleone (3-1) L: Dwayne Henry (0-2) S: Steve Farr (4) | Fourth | 5 out |
| Monday, April 26 |
| » Defeated Indians (7-12), 6-3 | Kingdome (7-5) | 9-10 | |
| » W: Randy Johnson (3-1) L: Tom Kramer (0-1) | Fourth | 4½ out |
| Tuesday, April 27 |
| » Defeated Indians (7-13), 4-0 | Kingdome (8-5) | 10-10 | Won 2 |
| » W: Chris Bosio (2-1) L: Charles Nagy (1-4) | Fourth | 3½ out |
| Wednesday, April 28 |
| » Defeated Indians (7-14), 4-0 | Kingdome (9-5) | 11-10 | Won 3 |
| » W: Erik Hanson (3-0) L: Jeff Mutis (1-2) S: Norm Charlton (3) | Fourth | 3½ out |
| Friday, April 30 |
| » Lost to Yankees (12-9), 3-0 | Yankee Stadium (0-1) | 11-11 | |
| » W: Melido Perez (1-1) L: John Cummings (0-4) S: Steve Farr (5) | Fourth | 3½ out |
| Saturday, May 1 |
| » Lost to Yankees (13-9), 6-2 | Yankee Stadium (0-2) | 11-12 | Lost 2 |
| » W: Mike Witt (1-0) L: Randy Johnson (3-2) | Fourth | 3½ out |
| Sunday, May 2 |
| » Lost to Yankees (14-9), 3-2 | Yankee Stadium (0-3) | 11-13 | Lost 3 |
| » W: John Habyan (1-1) L: Rich DeLucia (1-1) | Fourth | 3½ out |
| Monday, May 3 |
| » Defeated Red Sox (15-10), 2-0 | Fenway Park (1-0) | 12-13 | |
| » W: Erik Hanson (4-0) L: Frank Viola (4-2) S: Norm Charlton (4) | Fourth | 2½ out |
| Tuesday, May 4 |
| » Defeated Red Sox (15-11), 7-6 | Fenway Park (2-0) | 13-13 | Won 2 |
| » W: Tim Leary (1-1) L: Joe Hesketh (2-2) S: Norm Charlton (5) | Third | 1½ out |
| Wednesday, May 5 |
| » Lost to Indians (12-15), 3-2 | Cleveland Stadium (0-1) | 13-14 | |
| » W: Mike Bielecki (3-2) L: John Cummings (0-5) S: Derek Lilliquist (5) | Third | 2½ out |
| Thursday, May 6 |
| » Defeated Indians (12-16), 9-5 | Cleveland Stadium (1-1) | 14-14 | |
| » W: Randy Johnson (4-2) L: Jose Mesa (2-2) | Third | 2½ out |
| Friday, May 7 |
| » Lost to Twins (12-15), 5-4 | Kingdome (9-6) | 14-15 | |
| » W: Mark Guthrie (2-1) L: Russ Swan (1-2) S: Rick Aguilera (9) | Fourth | 3½ out |
| Saturday, May 8 |
| » Defeated Twins (12-16), 7-2 | Kingdome (10-6) | 15-15 | |
| » W: Erik Hanson (5-0) L: Jim Deshaies (4-2) | Fourth | 3 out |
| Sunday, May 9 |
| » Defeated Twins (12-17), 6-4 | Kingdome (11-6) | 16-15 | Won 2 |
| » W: Tim Leary (2-1) L: Scott Erickson (1-4) S: Norm Charlton (6) | Fourth | 3 out |
| Monday, May 10 |
| » Lost to White Sox (19-11), 13-2 | Kingdome (11-7) | 16-16 | |
| » W: Alex Fernandez (4-2) L: Mike Hampton (1-2) | Third | 4 out |
| Tuesday, May 11 |
| » Defeated White Sox (19-12), 4-3 | Kingdome (12-7) | 17-16 | |
| » W: Randy Johnson (5-2) L: Dave Stieb (1-1) S: Norm Charlton (7) | Fourth | 3 out |
| Wednesday, May 12 |
| » Lost to White Sox (20-12), 6-5 | Kingdome (12-8) | 17-17 | |
| » W: Wilson Alvarez (4-0) L: John Cummings (0-6) S: Roberto Hernandez (7) | Fourth | 4 out |
| » Major-league debuts: Zak Shinall (Mariners) |
| Friday, May 14 |
| » Lost to Athletics (13-19), 2-1 | Oakland-Alameda County Stadium (0-1) | 17-18 | Lost 2 |
| » W: Joe Boever (1-0) L: Rich DeLucia (1-2) | Fourth | 5 out |
| Saturday, May 15 |
| » Lost to Athletics (14-19), 2-1 | Oakland-Alameda County Stadium (0-2) | 17-19 | Lost 3 |
| » W: Rich Gossage (3-0) L: Jeff Nelson (0-1) | Fourth | 5 out |
| Sunday, May 16 |
| » Defeated Athletics (14-20), 7-0 | Oakland-Alameda County Stadium (1-2) | 18-19 | |
| » W: Randy Johnson (6-2) L: Bobby Witt (3-2) | Fourth | 5 out |
| Monday, May 17 |
| » Defeated Rangers (19-17), 16-9 | Arlington Stadium (1-0) | 19-19 | Won 2 |
| » W: Jeff Nelson (1-1) L: Craig Lefferts (1-5) | Fourth | 4 out |
| Tuesday, May 18 |
| » Lost to Rangers (20-17), 3-2 | Arlington Stadium (1-1) | 19-20 | |
| » W: Brian Bohanon (2-0) L: Rich DeLucia (1-3) S: Tom Henke (7) | Fourth | 5 out |
| Wednesday, May 19 |
| » Lost to Rangers (21-17), 4-3 | Arlington Stadium (1-2) | 19-21 | Lost 2 |
| » W: Tom Henke (3-1) L: Erik Hanson (5-1) | Fifth | 5 out |
| Thursday, May 20 |
| » Defeated Rangers (21-18), 7-4 | Arlington Stadium (2-2) | 20-21 | |
| » W: Tim Leary (3-1) L: Charlie Leibrandt (4-2) | Fourth | 4½ out |
| Friday, May 21 |
| » Lost to Royals (19-20), 2-1 | Royals Stadium (0-1) | 20-22 | |
| » W: Chris Haney (1-0) L: Randy Johnson (6-3) S: Tom Gordon (1) | Fifth | 4½ out |
| Saturday, May 22 |
| » Lost to Royals (20-20), 4-1 | Royals Stadium (0-2) | 20-23 | Lost 2 |
| » W: Kevin Appier (5-3) L: Jim Converse (0-1) | Fifth | 4½ out |
| » Major-league debuts: Jim Converse (Mariners) |
| Sunday, May 23 |
| » Defeated Royals (20-21), 10-7 | Royals Stadium (1-2) | 21-23 | |
| » W: Russ Swan (2-2) L: Jeff Montgomery (2-2) S: Norm Charlton (8) | Fifth | 4½ out |
| Monday, May 24 |
| » Defeated Angels (22-19), 4-3 | Kingdome (13-8) | 22-23 | Won 2 |
| » W: Dwayne Henry (1-2) L: Chuck Crim (2-2) | Fourth | 4 out |
| Tuesday, May 25 |
| » Lost to Angels (23-19), 6-3 | Kingdome (13-9) | 22-24 | |
| » W: Chuck Finley (4-4) L: Tim Leary (3-2) S: Steve Frey (3) | Fifth | 4 out |
| Wednesday, May 26 |
| » Defeated Angels (23-20), 2-0 | Kingdome (14-9) | 23-24 | |
| » W: Rich DeLucia (2-3) L: Scott Lewis (1-2) S: Norm Charlton (9) | Fifth | 3 out |
| Thursday, May 27 |
| » Lost to Angels (24-20), 5-0 | Kingdome (14-10) | 23-25 | |
| » W: Scott Sanderson (7-2) L: Jim Converse (0-2) | Fourth | 3 out |
| Friday, May 28 |
| » Defeated Tigers (29-17), 4-3 | Kingdome (15-10) | 24-25 | |
| » W: Russ Swan (3-2) L: Tom Bolton (1-2) | Fifth | 3 out |
| Saturday, May 29 |
| » Lost to Tigers (30-17), 3-2 | Kingdome (15-11) | 24-26 | |
| » W: Mark Leiter (4-1) L: Erik Hanson (5-2) S: Rob MacDonald (1) | Fourth | 4 out |
| Sunday, May 30 |
| » Defeated Tigers (30-18), 9-5 | Kingdome (16-11) | 25-26 | |
| » W: Norm Charlton (1-1) L: Bill Krueger (4-2) | Fourth | 4 out |
| Tuesday, June 1 |
| » Lost to Brewers (23-25), 10-0 | Kingdome (16-12) | 25-27 | |
| » W: Jaime Navarro (4-3) L: Chris Bosio (2-2) | Fifth | 3½ out |
| Wednesday, June 2 |
| » Defeated Brewers (23-26), 6-3 | Kingdome (17-12) | 26-27 | |
| » W: Jeff Nelson (2-1) L: Cal Eldred (6-6) S: Norm Charlton (10) | Third | 2½ out |
| Friday, June 4 |
| » Lost to Orioles (23-30), 6-5 | Oriole Park at Camden Yards (0-1) | 26-28 | |
| » W: Mark Williamson (3-1) L: Russ Swan (3-3) | Fifth | 4 out |
| Saturday, June 5 |
| » Lost to Orioles (24-30), 5-3 | Oriole Park at Camden Yards (0-2) | 26-29 | Lost 2 |
| » W: Brad Pennington (2-1) L: Erik Hanson (5-3) S: Gregg Olson (12) | Fifth | 4 out |
| Sunday, June 6 |
| » Lost to Orioles (25-30), 5-2 | Oriole Park at Camden Yards (0-3) | 26-30 | Lost 3 |
| » W: Mike Mussina (8-2) L: Chris Bosio (2-3) S: Gregg Olson (13) | Fourth | 5 out |
| Monday, June 7 |
| » Lost to Brewers (25-29), 5-3 | County Stadium (0-1) | 26-31 | Lost 4 |
| » W: Cal Eldred (7-6) L: Dave Fleming (0-1) S: Doug Henry (10) | Fifth | 6 out |
| Tuesday, June 8 |
| » Lost to Brewers (26-29), 2-1 | County Stadium (0-2) | 26-32 | Lost 5 |
| » W: Jim Austin (1-2) L: Tim Leary (3-3) S: Doug Henry (11) | Sixth | 6 out |
| Wednesday, June 9 |
| » Defeated Brewers (26-30), 6-1 | County Stadium (1-2) | 27-32 | |
| » W: Randy Johnson (7-3) L: Bill Wegman (4-9) | Fifth | 6 out |
| Friday, June 11 |
| » Lost to Angels (30-27), 8-2 | Anaheim Stadium (0-1) | 27-33 | |
| » W: Chuck Finley (6-5) L: Erik Hanson (5-4) | Fifth | 6 out |
| Saturday, June 12 |
| » Defeated Angels (30-28), 2-0 | Anaheim Stadium (1-1) | 28-33 | |
| » W: Dave Fleming (1-1) L: Scott Sanderson (7-5) | Sixth | 5 out |
| Sunday, June 13 |
| » Defeated Angels (30-29), 12-7 | Anaheim Stadium (2-1) | 29-33 | Won 2 |
| » W: Tim Leary (4-3) L: Julio Valera (3-6) | Sixth | 5 out |
| » Major-league debuts: Larry Gonzales (Angels) |
| Monday, June 14 |
| » Defeated Royals (33-28), 6-3 | Kingdome (18-12) | 30-33 | Won 3 |
| » W: Randy Johnson (8-3) L: Mark Gardner (4-3) S: Norm Charlton (11) | Fourth | 4 out |
| Tuesday, June 15 |
| » Defeated Royals (33-29), 6-1 | Kingdome (19-12) | 31-33 | Won 4 |
| » W: Jim Converse (1-2) L: Hipolito Pichardo (4-3) | Fifth | 3 out |
| Wednesday, June 16 |
| » Lost to Royals (34-29), 5-1 | Kingdome (19-13) | 31-34 | |
| » W: David Cone (4-7) L: Erik Hanson (5-5) | Fourth | 4 out |
| Friday, June 18 |
| » Defeated Rangers (31-34), 3-2 | Kingdome (20-13) | 32-34 | |
| » W: Dave Fleming (2-1) L: Roger Pavlik (3-3) S: Norm Charlton (12) | Third | 3 out |
| Saturday, June 19 |
| » Defeated Rangers (31-35), 6-5 | Kingdome (21-13) | 33-34 | Won 2 |
| » W: Randy Johnson (9-3) L: Todd Burns (0-4) S: Norm Charlton (13) | Fourth | 3 out |
| Sunday, June 20 |
| » Defeated Rangers (31-36), 13-2 | Kingdome (22-13) | 34-34 | Won 3 |
| » W: Tim Leary (5-3) L: Charlie Leibrandt (7-4) | Third | 2 out |
| Monday, June 21 |
| » Lost to Athletics (27-38), 5-3 | Kingdome (22-14) | 34-35 | |
| » W: Storm Davis (2-5) L: Rich DeLucia (2-4) S: Dennis Eckersley (15) | Second | 2 out |
| Tuesday, June 22 |
| » Lost to Athletics (28-38), 10-3 | Kingdome (22-15) | 34-36 | Lost 2 |
| » W: Bobby Witt (7-4) L: Jim Converse (1-3) | Third | 3 out |
| Wednesday, June 23 |
| » Defeated Athletics (28-39), 8-7 | Kingdome (23-15) | 35-36 | |
| » W: Dwayne Henry (2-2) L: Shawn Hillegas (2-6) | Third | 3 out |
| Thursday, June 24 |
| » Lost to Athletics (29-39), 3-2 | Kingdome (23-16) | 35-37 | |
| » W: Dennis Eckersley (2-1) L: Randy Johnson (9-4) | Fourth | 3½ out |
| Friday, June 25 |
| » Defeated White Sox (37-33), 3-2 | Comiskey Park II (1-0) | 36-37 | |
| » W: Tim Leary (6-3) L: Wilson Alvarez (7-3) S: Norm Charlton (14) | Fourth | 2½ out |
| Saturday, June 26 |
| » Lost to White Sox (38-33), 7-4 | Comiskey Park II (1-1) | 36-38 | |
| » W: Jack McDowell (12-4) L: Erik Hanson (5-6) S: Roberto Hernandez (13) | Third | 3½ out |
| Sunday, June 27 |
| » Lost to White Sox (39-33), 6-4 | Comiskey Park II (1-2) | 36-39 | Lost 2 |
| » W: Alex Fernandez (8-4) L: Rich DeLucia (2-5) S: Roberto Hernandez (14) | Third | 4½ out |
| Monday, June 28 |
| » Defeated Twins (31-41), 4-1 | Hubert H. Humphrey Metrodome (1-0) | 37-39 | |
| » W: Dave Fleming (3-1) L: Kevin Tapani (3-9) S: Norm Charlton (15) | Fourth | 3½ out |
| Tuesday, June 29 |
| » Lost to Twins (32-41), 7-5 | Hubert H. Humphrey Metrodome (1-1) | 37-40 | |
| » W: Mike Trombley (4-3) L: Bob Ayrault (2-1) S: Rick Aguilera (22) | Fourth | 3½ out |
| Wednesday, June 30 |
| » Defeated Twins (32-42), 5-3 | Hubert H. Humphrey Metrodome (2-1) | 38-40 | |
| » W: Randy Johnson (10-4) L: Scott Erickson (4-9) S: Norm Charlton (16) | Fourth | 2½ out |
| Thursday, July 1 |
| » Defeated Twins (32-43), 6-1 | Hubert H. Humphrey Metrodome (3-1) | 39-40 | Won 2 |
| » W: Erik Hanson (6-6) L: Willie Banks (5-5) | Third | 1½ out |
| Friday, July 2 |
| » Lost to Red Sox (39-39), 9-8 | Kingdome (23-17) | 39-41 | |
| » W: Frank Viola (5-7) L: Mike Hampton (1-3) S: Jeff Russell (17) | Third | 2½ out |
| Saturday, July 3 |
| » Lost to Red Sox (40-39), 6-5 | Kingdome (23-18) | 39-42 | Lost 2 |
| » W: Greg Harris (4-3) L: Norm Charlton (1-2) S: Jeff Russell (18) | Second | 2½ out |
| Sunday, July 4 |
| » Lost to Red Sox (41-39), 6-0 | Kingdome (23-19) | 39-43 | Lost 3 |
| » W: Paul Quantrill (4-5) L: Chris Bosio (2-4) | Third | 3½ out |
| » Major-league debuts: Brad Holman (Mariners) |
| Monday, July 5 |
| » Lost to Yankees (47-36), 6-3 | Kingdome (23-20) | 39-44 | Lost 4 |
| » W: Scott Kamieniecki (3-2) L: Randy Johnson (10-5) S: Steve Howe (3) | Fourth | 4½ out |
| Tuesday, July 6 |
| » Defeated Yankees (47-37), 12-4 | Kingdome (24-20) | 40-44 | |
| » W: Erik Hanson (7-6) L: Jim Abbott (5-8) | Fourth | 3½ out |
| » Major-league debuts: Marc Newfield (Mariners) |
| Wednesday, July 7 |
| » Defeated Yankees (47-38), 6-5 | Kingdome (25-20) | 41-44 | Won 2 |
| » W: Tim Leary (7-3) L: Bob Wickman (8-3) S: Norm Charlton (17) | Fourth | 3½ out |
| Friday, July 9 |
| » Defeated Indians (40-46), 6-4 | Kingdome (26-20) | 42-44 | Won 3 |
| » W: Dave Fleming (4-1) L: Cliff Young (2-3) S: Chris Bosio (1) | Fifth | 3 out |
| Saturday, July 10 |
| » Defeated Indians (40-47), 7-6 | Kingdome (27-20) | 43-44 | Won 4 |
| » W: Chris Bosio (3-4) L: Jeremy Hernandez (1-4) | Fourth | 2 out |
| Sunday, July 11 |
| » Defeated Indians (40-48), 5-4 | Kingdome (28-20) | 44-44 | Won 5 |
| » W: Bob Ayrault (3-1) L: Eric Plunk (4-3) | Fourth | 2 out |
| Thursday, July 15 |
| » Defeated Red Sox (45-43), 3-2 | Fenway Park (3-0) | 45-44 | Won 6 |
| » W: Dave Fleming (5-1) L: Frank Viola (5-8) S: Mike Hampton (1) | Third | 2 out |
| Friday, July 16 |
| » Lost to Red Sox (46-43), 5-3 | Fenway Park (3-1) | 45-45 | |
| » W: Roger Clemens (8-6) L: Erik Hanson (7-7) S: Jeff Russell (21) | Fifth | 3 out |
| Saturday, July 17 |
| » Lost to Red Sox (47-43), 4-3 | Fenway Park (3-2) | 45-46 | Lost 2 |
| » W: Danny Darwin (9-7) L: Chris Bosio (3-5) S: Jeff Russell (22) | Third | 4 out |
| Sunday, July 18 |
| » Lost to Red Sox (48-43), 7-6 | Fenway Park (3-3) | 45-47 | Lost 3 |
| » W: Ken Ryan (3-0) L: Norm Charlton (1-3) S: Greg Harris (4) | Fourth | 5 out |
| Monday, July 19 |
| » Lost to Yankees (52-42), 8-2 | Yankee Stadium (0-4) | 45-48 | Lost 4 |
| » W: Scott Kamieniecki (4-3) L: Tim Leary (7-4) | Fifth | 5 out |
| Tuesday, July 20 |
| » Defeated Yankees (52-43), 9-5 | Yankee Stadium (1-4) | 46-48 | |
| » W: Dave Fleming (6-1) L: Steve Howe (3-4) | Fourth | 5 out |
| Wednesday, July 21 |
| » Defeated Yankees (52-44), 10-3 | Yankee Stadium (2-4) | 47-48 | Won 2 |
| » W: Erik Hanson (8-7) L: Jimmy Key (12-3) | Fourth | 4 out |
| Thursday, July 22 |
| » Defeated Indians (45-51), 3-2 | Cleveland Stadium (2-1) | 48-48 | Won 3 |
| » W: Chris Bosio (4-5) L: Jeff Mutis (2-3) S: Brad Holman (1) | Fourth | 4 out |
| Friday, July 23 |
| » Lost to Indians (46-51), 9-4 | Cleveland Stadium (2-2) | 48-49 | |
| » W: Albie Lopez (2-0) L: Randy Johnson (10-6) | Fourth | 4 out |
| Saturday, July 24 |
| » Defeated Indians (46-52), 6-5 | Cleveland Stadium (3-2) | 49-49 | |
| » W: Jeff Nelson (3-1) L: Jerry Dipoto (1-1) S: Brad Holman (2) | Fourth | 4 out |
| Sunday, July 25 |
| » Lost to Indians (47-52), 11-9 | Cleveland Stadium (3-3) | 49-50 | |
| » W: Jeremy Hernandez (2-4) L: Jeff Nelson (3-2) S: Derek Lilliquist (9) | Fourth | 4 out |
| Tuesday, July 27 |
| » Defeated Twins (42-55), 10-8 | Kingdome (29-20) | 50-50 | |
| » W: Rich DeLucia (3-5) L: George Tsamis (1-2) S: Jeff Nelson (1) | Fourth | 4½ out |
| Wednesday, July 28 |
| » Lost to Twins (43-55), 5-1 | Kingdome (29-21) | 50-51 | |
| » W: Willie Banks (7-7) L: Randy Johnson (10-7) S: Larry Casian (1) | Fourth | 5½ out |
| Thursday, July 29 |
| » Defeated Twins (43-56), 4-3 | Kingdome (30-21) | 51-51 | |
| » W: Tim Leary (8-4) L: Scott Erickson (6-12) S: Ted Power (1) | Fourth | 5 out |
| Friday, July 30 |
| » Lost to White Sox (56-45), 6-4 | Kingdome (30-22) | 51-52 | |
| » W: Scott Radinsky (6-0) L: Rich DeLucia (3-6) S: Roberto Hernandez (22) | Fourth | 6 out |
| Saturday, July 31 |
| » Lost to White Sox (57-45), 13-10 | Kingdome (30-23) | 51-53 | Lost 2 |
| » W: Rodney Bolton (2-6) L: Erik Hanson (8-8) S: Scott Radinsky (3) | Fourth | 7 out |
| » Major-league debuts: Erik Plantenberg (Mariners) |
| Sunday, August 1 |
| » Lost to White Sox (58-45), 4-0 | Kingdome (30-24) | 51-54 | Lost 3 |
| » W: Jack McDowell (17-6) L: Chris Bosio (4-6) | Fourth | 8 out |
| Tuesday, August 3 |
| » Defeated Athletics (44-59), 5-4 | Oakland-Alameda County Stadium (2-2) | 52-54 | |
| » W: Randy Johnson (11-7) L: Edwin Nunez (3-6) S: Ted Power (2) | Fourth | 7½ out |
| Wednesday, August 4 |
| » Lost to Athletics (45-59), 5-4 | Oakland-Alameda County Stadium (2-3) | 52-55 | |
| » W: Kelly Downs (3-5) L: Jeff Nelson (3-3) | Fourth | 7½ out |
| Thursday, August 5 |
| » Defeated Athletics (45-60), 3-2 | Oakland-Alameda County Stadium (3-3) | 53-55 | |
| » W: Dave Fleming (7-1) L: Bobby Witt (8-10) S: Norm Charlton (18) | Third | 6½ out |
| Friday, August 6 |
| » Lost to Rangers (56-53), 5-3 | Arlington Stadium (2-3) | 53-56 | |
| » W: Kenny Rogers (9-7) L: Chris Bosio (4-7) S: Tom Henke (24) | Fourth | 6½ out |
| Saturday, August 7 |
| » Defeated Rangers (56-54), 2-1 | Arlington Stadium (3-3) | 54-56 | |
| » W: Erik Hanson (9-8) L: Roger Pavlik (6-6) S: Dwayne Henry (2) | Third | 6½ out |
| Sunday, August 8 |
| » Lost to Rangers (57-54), 7-1 | Arlington Stadium (3-4) | 54-57 | |
| » W: Steve Dreyer (1-0) L: Randy Johnson (11-8) | Third | 6½ out |
| » Major-league debuts: Steve Dreyer (Rangers) |
| Monday, August 9 |
| » Lost to Royals (58-54), 7-6 | Royals Stadium (1-3) | 54-58 | Lost 2 |
| » W: Stan Belinda (4-2) L: Ted Power (0-3) S: Jeff Montgomery (35) | Fourth | 7½ out |
| Tuesday, August 10 |
| » Lost to Royals (59-54), 4-1 | Royals Stadium (1-4) | 54-59 | Lost 3 |
| » W: Tom Gordon (7-3) L: Dave Fleming (7-2) S: Mark Gubicza (2) | Fourth | 8½ out |
| Wednesday, August 11 |
| » Defeated Royals (59-55), 4-3 | Royals Stadium (2-4) | 55-59 | |
| » W: Chris Bosio (5-7) L: Chris Haney (7-5) S: Ted Power (3) | Fourth | 7½ out |
| Friday, August 13 |
| » Defeated Angels (53-61), 2-1 | Kingdome (31-24) | 56-59 | Won 2 |
| » W: Erik Hanson (10-8) L: Chuck Finley (13-9) | Fourth | 7 out |
| » Major-league debuts: Greg Pirkl and Brian Turang (Mariners) |
| Saturday, August 14 |
| » Defeated Angels (53-62), 7-2 | Kingdome (32-24) | 57-59 | Won 3 |
| » W: Randy Johnson (12-8) L: Mark Langston (12-6) | Fourth | 7 out |
| Sunday, August 15 |
| » Lost to Angels (54-62), 14-2 | Kingdome (32-25) | 57-60 | |
| » W: Phil Leftwich (1-3) L: Tim Leary (8-5) | Fourth | 7 out |
| Monday, August 16 |
| » Defeated Orioles (63-56), 8-6 | Kingdome (33-25) | 58-60 | |
| » W: Dave Fleming (8-2) L: Rick Sutcliffe (9-9) S: Randy Johnson (1) | Fourth | 6½ out |
| Tuesday, August 17 |
| » Defeated Orioles (63-57), 5-3 | Kingdome (34-25) | 59-60 | Won 2 |
| » W: Chris Bosio (6-7) L: Todd Frohwirth (6-6) S: Ted Power (4) | Fourth | 6½ out |
| Wednesday, August 18 |
| » Lost to Orioles (64-57), 8-1 | Kingdome (34-26) | 59-61 | |
| » W: Jamie Moyer (8-6) L: Erik Hanson (10-9) | Fourth | 6½ out |
| Friday, August 20 |
| » Defeated Blue Jays (71-52), 4-1 | Skydome (2-2) | 60-61 | |
| » W: Randy Johnson (13-8) L: Pat Hentgen (14-7) | Fourth | 6½ out |
| Saturday, August 21 |
| » Defeated Blue Jays (71-53), 5-2 | Skydome (3-2) | 61-61 | Won 2 |
| » W: Dave Fleming (9-2) L: Dave Stewart (8-7) S: Ted Power (5) | Fourth | 6½ out |
| Sunday, August 22 |
| » Lost to Blue Jays (72-53), 12-7 | Skydome (3-3) | 61-62 | |
| » W: Juan Guzman (10-3) L: Steve Ontiveros (0-1) | Fourth | 7½ out |
| Tuesday, August 24 |
| » Lost to Tigers (67-61), 4-1 | Tiger Stadium (1-4) | 61-63 | Lost 2 |
| » W: John Doherty (11-9) L: Erik Hanson (10-10) | Fourth | 8 out |
| Wednesday, August 25 |
| » Lost to Tigers (68-61), 7-4 | Tiger Stadium (1-5) | 61-64 | Lost 3 |
| » W: Bill Gullickson (11-6) L: Tim Leary (8-6) S: Storm Davis (2) | Fourth | 8 out |
| Thursday, August 26 |
| » Defeated Blue Jays (74-55), 6-3 | Kingdome (35-26) | 62-64 | |
| » W: Randy Johnson (14-8) L: Dave Stewart (8-8) S: Ted Power (6) | Fourth | 7½ out |
| Friday, August 27 |
| » Defeated Blue Jays (74-56), 7-6 | Kingdome (36-26) | 63-64 | Won 2 |
| » W: Jeff Nelson (4-3) L: Woody Williams (3-1) S: Erik Plantenberg (1) | Fourth | 7 out |
| Saturday, August 28 |
| » Defeated Blue Jays (74-57), 2-1 | Kingdome (37-26) | 64-64 | Won 3 |
| » W: Chris Bosio (7-7) L: Danny Cox (6-6) S: Ted Power (7) | Fourth | 7 out |
| Sunday, August 29 |
| » Lost to Blue Jays (75-57), 6-2 | Kingdome (37-27) | 64-65 | |
| » W: Todd Stottlemyre (8-9) L: Erik Hanson (10-11) | Fourth | 8 out |
| Monday, August 30 |
| » Lost to Tigers (71-62), 13-2 | Kingdome (37-28) | 64-66 | Lost 2 |
| » W: Bill Gullickson (12-6) L: Tim Leary (8-7) | Fourth | 9 out |
| Tuesday, August 31 |
| » Defeated Tigers (71-63), 5-4 | Kingdome (38-28) | 65-66 | |
| » W: Jeff Nelson (5-3) L: Mike Henneman (3-3) S: Ted Power (8) | Fourth | 9 out |
| Wednesday, September 1 |
| » Defeated Tigers (71-64), 9-3 | Kingdome (39-28) | 66-66 | Won 2 |
| » W: Dave Fleming (10-2) L: Mike Moore (11-7) | Fourth | 9 out |
| Thursday, September 2 |
| » Defeated Brewers (58-78), 8-1 | Kingdome (40-28) | 67-66 | Won 3 |
| » W: Chris Bosio (8-7) L: Teddy Higuera (0-2) | Fourth | 8 out |
| » Major-league debuts: Kevin King (Mariners) |
| Friday, September 3 |
| » Lost to Brewers (59-78), 7-4 | Kingdome (40-29) | 67-67 | |
| » W: Jesse Orosco (2-3) L: Brad Holman (0-1) S: Matt Maysey (1) | Fourth | 9 out |
| Saturday, September 4 |
| » Defeated Brewers (59-79), 6-1 | Kingdome (41-29) | 68-67 | |
| » W: Tim Leary (9-7) L: Cal Eldred (15-13) S: Ted Power (9) | Fourth | 9 out |
| Sunday, September 5 |
| » Defeated Brewers (59-80), 3-2 | Kingdome (42-29) | 69-67 | Won 2 |
| » W: Randy Johnson (15-8) L: Angel Miranda (3-5) | Fourth | 9 out |
| Monday, September 6 |
| » Lost to Orioles (76-62), 5-1 | Oriole Park at Camden Yards (0-4) | 69-68 | |
| » W: Ben McDonald (11-11) L: Dave Fleming (10-3) S: Alan Mills (2) | Fourth | 9 out |
| Tuesday, September 7 |
| » Defeated Orioles (76-63), 3-2 | Oriole Park at Camden Yards (1-4) | 70-68 | |
| » W: Brad Holman (1-1) L: Arthur Rhodes (4-4) S: Ted Power (10) | Fourth | 8 out |
| Wednesday, September 8 |
| » Lost to Orioles (77-63), 6-3 | Oriole Park at Camden Yards (1-5) | 70-69 | |
| » W: Jim Poole (2-1) L: Kevin King (0-1) | Fourth | 9 out |
| » Major-league debuts: Roger Salkeld (Mariners) |
| Friday, September 10 |
| » Defeated Brewers (61-81), 10-3 | County Stadium (2-2) | 71-69 | |
| » W: Tim Leary (10-7) L: Teddy Higuera (0-3) | Fourth | 8 out |
| Saturday, September 11 |
| » Defeated Brewers (61-82), 7-3 | County Stadium (3-2) | 72-69 | Won 2 |
| » W: Randy Johnson (16-8) L: Cal Eldred (15-14) S: Brad Holman (3) | Fourth | 8 out |
| Sunday, September 12 |
| » Defeated Brewers (61-83), 5-4 | County Stadium (4-2) | 73-69 | Won 3 |
| » W: Ted Power (1-3) L: Jesse Orosco (2-4) | Fourth | 7 out |
| Monday, September 13 |
| » Defeated Angels (63-80), 10-1 | Anaheim Stadium (3-1) | 74-69 | Won 4 |
| » W: Chris Bosio (9-7) L: Mark Langston (15-8) | Fourth | 6 out |
| Tuesday, September 14 |
| » Lost to Angels (64-80), 9-2 | Anaheim Stadium (3-2) | 74-70 | |
| » W: Joe Magrane (11-11) L: Erik Hanson (10-12) | Fourth | 7 out |
| Wednesday, September 15 |
| » Lost to Angels (65-80), 15-1 | Anaheim Stadium (3-3) | 74-71 | Lost 2 |
| » W: Phil Leftwich (3-5) L: Tim Leary (10-8) | Fourth | 8 out |
| Thursday, September 16 |
| » Defeated Royals (75-71), 14-1 | Kingdome (43-29) | 75-71 | |
| » W: Randy Johnson (17-8) L: Chris Haney (9-9) | Third | 7½ out |
| » Major-league debuts: Jeff Granger (Royals) |
| Friday, September 17 |
| » Lost to Royals (76-71), 6-3 | Kingdome (43-30) | 75-72 | |
| » W: Tom Gordon (11-6) L: Dave Fleming (10-4) S: Jeff Montgomery (43) | Fourth | 8½ out |
| Saturday, September 18 |
| » Lost to Royals (77-71), 1-0 | Kingdome (43-31) | 75-73 | Lost 2 |
| » W: Kevin Appier (17-6) L: Chris Bosio (9-8) | Fourth | 8½ out |
| Sunday, September 19 |
| » Defeated Royals (77-72), 4-1 | Kingdome (44-31) | 76-73 | |
| » W: Erik Hanson (11-12) L: Mike Magnante (1-2) S: Ted Power (11) | Fourth | 8½ out |
| Monday, September 20 |
| » Lost to Rangers (81-69), 2-1 | Kingdome (44-32) | 76-74 | |
| » W: Cris Carpenter (4-2) L: Brad Holman (1-2) S: Tom Henke (38) | Fourth | 9½ out |
| Tuesday, September 21 |
| » Defeated Rangers (81-70), 8-0 | Kingdome (45-32) | 77-74 | |
| » W: Randy Johnson (18-8) L: Charlie Leibrandt (9-10) | Third | 8½ out |
| Wednesday, September 22 |
| » Defeated Rangers (81-71), 7-4 | Kingdome (46-32) | 78-74 | Won 2 |
| » W: Dave Fleming (11-4) L: Nolan Ryan (5-5) S: Ted Power (12) | Third | 8½ out |
| Friday, September 24 |
| » Lost to Athletics (64-89), 5-3 | Kingdome (46-33) | 78-75 | |
| » W: Steve Karsay (3-3) L: Chris Bosio (9-9) S: Dennis Eckersley (35) | Fourth | 10 out |
| Saturday, September 25 |
| » Lost to Athletics (65-89), 7-2 | Kingdome (46-34) | 78-76 | Lost 2 |
| » W: Vince Horsman (2-0) L: Ted Power (1-4) | Fourth | 10½ out |
| Sunday, September 26 |
| » Lost to Athletics (66-89), 3-2 | Kingdome (46-35) | 78-77 | Lost 3 |
| » W: John Briscoe (1-0) L: Steve Ontiveros (0-2) S: Dennis Eckersley (36) | Fourth | 11 out |
| Monday, September 27 |
| » Lost to White Sox (90-66), 4-2 | Comiskey Park II (1-3) | 78-78 | Lost 4 |
| » W: Wilson Alvarez (15-8) L: Dave Fleming (11-5) S: Kirk McCaskill (2) | Fourth | 12 out |
| Tuesday, September 28 |
| » Defeated White Sox (90-67), 5-2 | Comiskey Park II (2-3) | 79-78 | |
| » W: Tim Leary (11-8) L: Scott Ruffcorn (0-2) S: Ted Power (13) | Fourth | 11 out |
| Wednesday, September 29 |
| » Lost to White Sox (91-67), 3-2 | Comiskey Park II (2-4) | 79-79 | |
| » W: Scott Radinsky (8-2) L: Brad Holman (1-3) | Fourth | 12 out |
| Thursday, September 30 |
| » Defeated White Sox (91-68), 2-1 | Comiskey Park II (3-4) | 80-79 | |
| » W: Ted Power (2-4) L: Kirk McCaskill (4-8) | Fourth | 11 out |
| Friday, October 1 |
| » Defeated Twins (70-90), 8-2 | Hubert H. Humphrey Metrodome (4-1) | 81-79 | Won 2 |
| » W: Randy Johnson (19-8) L: Mike Trombley (6-6) | Fourth | 11 out |
| Saturday, October 2 |
| » Defeated Twins (70-91), 7-3 | Hubert H. Humphrey Metrodome (5-1) | 82-79 | Won 3 |
| » W: Dave Fleming (12-5) L: Willie Banks (11-12) | Fourth | 11 out |
| Sunday, October 3 |
| » Lost to Twins (71-91), 7-2 | Hubert H. Humphrey Metrodome (5-2) | 82-80 | |
| » W: Kevin Tapani (12-15) L: Tim Leary (11-9) | Fourth | 12 out |
Game information provided by Retrosheet (www.retrosheet.org) |