| Monday, April 5 |
| » Lost to Phillies (1-0), 3-1 | Astrodome (0-1) | 0-1 | |
| » W: Terry Mulholland (1-0) L: Doug Drabek (0-1) | Third | 1 out |
| Tuesday, April 6 |
| » Lost to Phillies (2-0), 5-3 | Astrodome (0-2) | 0-2 | Lost 2 |
| » W: Curt Schilling (1-0) L: Greg Swindell (0-1) S: Mitch Williams (1) | Fourth | 1½ out |
| Wednesday, April 7 |
| » Lost to Phillies (3-0), 6-3 | Astrodome (0-3) | 0-3 | Lost 3 |
| » W: Jose DeLeon (1-0) L: Eric Bell (0-1) S: Mitch Williams (2) | Fifth | 2 out |
| Friday, April 9 |
| » Defeated Mets (2-1), 7-3 | Shea Stadium (1-0) | 1-3 | |
| » W: Doug Jones (1-0) L: Anthony Young (0-1) | Fourth | 2½ out |
| Saturday, April 10 |
| » Defeated Mets (2-2), 6-3 | Shea Stadium (2-0) | 2-3 | Won 2 |
| » W: Doug Drabek (1-1) L: Dwight Gooden (1-1) | Fourth | 1½ out |
| » Major-league debuts: Mike Draper (Mets) |
| Sunday, April 11 |
| » Defeated Mets (2-3), 5-4 | Shea Stadium (3-0) | 3-3 | Won 3 |
| » W: Greg Swindell (1-1) L: Pete Schourek (0-1) S: Doug Jones (1) | Second | 1½ out |
| Tuesday, April 13 |
| » Defeated Expos (3-4), 9-6 | Stade Olympique (1-0) | 4-3 | Won 4 |
| » W: Brian Williams (1-0) L: Mel Rojas (0-1) | Third | 1 out |
| Wednesday, April 14 |
| » Defeated Expos (3-5), 9-5 | Stade Olympique (2-0) | 5-3 | Won 5 |
| » W: Mark Portugal (1-0) L: Mike Gardiner (0-1) | First | -- |
| Thursday, April 15 |
| » Lost to Expos (4-5), 2-1 | Stade Olympique (2-1) | 5-4 | |
| » W: Jimmy Jones (2-0) L: Doug Drabek (1-2) S: Mel Rojas (3) | Second | ½ out |
| Friday, April 16 |
| » Defeated Marlins (3-7), 9-3 | Astrodome (1-3) | 6-4 | |
| » W: Greg Swindell (2-1) L: Charlie Hough (2-1) | Second | ½ out |
| Saturday, April 17 |
| » Lost to Marlins (4-7), 9-4 | Astrodome (1-4) | 6-5 | |
| » W: Jack Armstrong (1-2) L: Brian Williams (1-1) | Second | ½ out |
| Sunday, April 18 |
| » Defeated Marlins (4-8), 3-0 | Astrodome (2-4) | 7-5 | |
| » W: Pete Harnisch (1-0) L: Chris Hammond (0-2) S: Doug Jones (2) | Second | ½ out |
| Tuesday, April 20 |
| » Lost to Cubs (7-6), 2-1 | Wrigley Field (0-1) | 7-6 | |
| » W: Mike Harkey (2-0) L: Mark Portugal (1-1) S: Randy Myers (4) | Second | 1½ out |
| Wednesday, April 21 |
| » Defeated Cubs (7-7), 2-0 | Wrigley Field (1-1) | 8-6 | |
| » W: Doug Drabek (2-2) L: Mike Morgan (1-3) | Second | ½ out |
| Friday, April 23 |
| » Defeated Pirates (8-8), 4-2 | Three Rivers Stadium (1-0) | 9-6 | Won 2 |
| » W: Greg Swindell (3-1) L: Denny Neagle (0-1) S: Doug Jones (3) | First | -- |
| Saturday, April 24 |
| » Defeated Pirates (8-9), 8-4 | Three Rivers Stadium (2-0) | 10-6 | Won 3 |
| » W: Xavier Hernandez (1-0) L: John Candelaria (0-2) | First | -- |
| Sunday, April 25 |
| » Lost to Pirates (9-9), 7-2 | Three Rivers Stadium (2-1) | 10-7 | |
| » W: Randy Tomlin (1-1) L: Mark Portugal (1-2) | First | -- |
| Monday, April 26 |
| » Lost to Cardinals (11-8), 3-2 | Astrodome (2-5) | 10-8 | Lost 2 |
| » W: Joe Magrane (1-2) L: Doug Drabek (2-3) S: Lee Smith (8) | First | -- |
| Tuesday, April 27 |
| » Defeated Cardinals (11-9), 9-2 | Astrodome (3-5) | 11-8 | |
| » W: Darryl Kile (1-0) L: Rheal Cormier (1-2) S: Brian Williams (1) | First | -- |
| Wednesday, April 28 |
| » Defeated Cubs (10-10), 6-1 | Astrodome (4-5) | 12-8 | Won 2 |
| » W: Greg Swindell (4-1) L: Jose Guzman (3-2) | First | -- |
| Thursday, April 29 |
| » Defeated Cubs (10-11), 5-4 | Astrodome (5-5) | 13-8 | Won 3 |
| » W: Pete Harnisch (2-0) L: Greg Hibbard (1-2) S: Doug Jones (4) | First | -- |
| Friday, April 30 |
| » Defeated Pirates (11-11), 11-2 | Astrodome (6-5) | 14-8 | Won 4 |
| » W: Mark Portugal (2-2) L: Bob Walk (2-2) S: Xavier Hernandez (1) | First | -- |
| » Major-league debuts: Rich Robertson (Pirates) |
| Saturday, May 1 |
| » Defeated Pirates (11-12), 7-3 | Astrodome (7-5) | 15-8 | Won 5 |
| » W: Doug Drabek (3-3) L: Randy Tomlin (1-2) | First | -- |
| Sunday, May 2 |
| » Lost to Pirates (12-12), 6-2 | Astrodome (7-6) | 15-9 | |
| » W: Steve Cooke (1-1) L: Greg Swindell (4-2) | Second | 1 out |
| Tuesday, May 4 |
| » Lost to Cardinals (15-11), 6-1 | Busch Stadium II (0-1) | 15-10 | Lost 2 |
| » W: Bob Tewksbury (2-3) L: Pete Harnisch (2-1) | Second | 1 out |
| Wednesday, May 5 |
| » Defeated Cardinals (15-12), 6-3 | Busch Stadium II (1-1) | 16-10 | |
| » W: Mark Portugal (3-2) L: Donovan Osborne (1-1) S: Doug Jones (5) | Second | 1 out |
| Thursday, May 6 |
| » Lost to Reds (11-16), 5-4 | Astrodome (7-7) | 16-11 | |
| » W: Milt Hill (1-0) L: Doug Jones (1-1) S: Jeff Reardon (3) | Second | 1½ out |
| Friday, May 7 |
| » Lost to Reds (12-16), 7-5 | Astrodome (7-8) | 16-12 | Lost 2 |
| » W: Jose Rijo (4-1) L: Greg Swindell (4-3) S: Jeff Reardon (4) | Second | 2½ out |
| Saturday, May 8 |
| » Defeated Reds (12-17), 12-1 | Astrodome (8-8) | 17-12 | |
| » W: Darryl Kile (2-0) L: John Smiley (0-5) | Second | 1½ out |
| Sunday, May 9 |
| » Defeated Reds (12-18), 6-3 | Astrodome (9-8) | 18-12 | Won 2 |
| » W: Pete Harnisch (3-1) L: Tim Pugh (2-3) S: Doug Jones (6) | Second | ½ out |
| Monday, May 10 |
| » Defeated Braves (18-16), 5-2 | Astrodome (10-8) | 19-12 | Won 3 |
| » W: Xavier Hernandez (2-0) L: Jay Howell (1-2) S: Doug Jones (7) | First | -- |
| Tuesday, May 11 |
| » Lost to Braves (19-16), 5-4 | Astrodome (10-9) | 19-13 | |
| » W: John Smoltz (4-3) L: Doug Drabek (3-4) S: Mike Stanton (12) | Second | ½ out |
| Wednesday, May 12 |
| » Lost to Braves (20-16), 5-2 | Astrodome (10-10) | 19-14 | Lost 2 |
| » W: Steve Avery (2-2) L: Greg Swindell (4-4) S: Mike Stanton (13) | Second | 1½ out |
| Friday, May 14 |
| » Defeated Dodgers (14-20), 9-1 | Astrodome (11-10) | 20-14 | |
| » W: Pete Harnisch (4-1) L: Tom Candiotti (1-4) | Second | 1 out |
| Saturday, May 15 |
| » Defeated Dodgers (14-21), 7-1 | Astrodome (12-10) | 21-14 | Won 2 |
| » W: Mark Portugal (4-2) L: Orel Hershiser (4-4) | Second | 1 out |
| Sunday, May 16 |
| » Defeated Dodgers (14-22), 3-2 | Astrodome (13-10) | 22-14 | Won 3 |
| » W: Doug Drabek (4-4) L: Pedro Martinez (1-2) S: Doug Jones (8) | Second | 1 out |
| Monday, May 17 |
| » Lost to Giants (25-14), 8-7 | Candlestick Park (0-1) | 22-15 | |
| » W: Dave Burba (3-2) L: Doug Jones (1-2) | Second | 2 out |
| Tuesday, May 18 |
| » Lost to Giants (26-14), 7-2 | Candlestick Park (0-2) | 22-16 | Lost 2 |
| » W: John Burkett (7-0) L: Darryl Kile (2-1) | Second | 3 out |
| Wednesday, May 19 |
| » Lost to Giants (27-14), 6-3 | Candlestick Park (0-3) | 22-17 | Lost 3 |
| » W: Jeff Brantley (3-3) L: Pete Harnisch (4-2) | Third | 4 out |
| Friday, May 21 |
| » Lost to Padres (18-23), 3-2 | San Diego/Jack Murphy Stadium (0-1) | 22-18 | Lost 4 |
| » W: Rich Rodriguez (2-2) L: Doug Jones (1-3) | Third | 5½ out |
| Saturday, May 22 |
| » Lost to Padres (19-23), 9-4 | San Diego/Jack Murphy Stadium (0-2) | 22-19 | Lost 5 |
| » W: Andy Benes (7-3) L: Doug Drabek (4-5) | Third | 5½ out |
| Sunday, May 23 |
| » Defeated Padres (19-24), 9-7 | San Diego/Jack Murphy Stadium (1-2) | 23-19 | |
| » W: Greg Swindell (5-4) L: Dave Eiland (0-3) S: Doug Jones (9) | Third | 5½ out |
| Tuesday, May 25 |
| » Lost to Rockies (13-32), 7-5 | Astrodome (13-11) | 23-20 | |
| » W: Gary Wayne (2-2) L: Xavier Hernandez (2-1) S: Andy Ashby (1) | Third | 6½ out |
| Wednesday, May 26 |
| » Lost to Rockies (14-32), 3-2 | Astrodome (13-12) | 23-21 | Lost 2 |
| » W: Bryn Smith (2-3) L: Doug Jones (1-4) S: Jeff Parrett (1) | Third | 6½ out |
| Thursday, May 27 |
| » Defeated Rockies (14-33), 8-0 | Astrodome (14-12) | 24-21 | |
| » W: Doug Drabek (5-5) L: David Nied (3-7) | Third | 5½ out |
| Friday, May 28 |
| » Lost to Marlins (21-26), 5-4 | Joe Robbie Stadium (0-1) | 24-22 | |
| » W: Richie Lewis (3-0) L: Tom Edens (0-1) | Third | 5½ out |
| Saturday, May 29 |
| » Defeated Marlins (21-27), 4-2 | Joe Robbie Stadium (1-1) | 25-22 | |
| » W: Darryl Kile (3-1) L: Charlie Hough (2-6) S: Doug Jones (10) | Third | 5½ out |
| Sunday, May 30 |
| » Defeated Marlins (21-28), 2-1 | Joe Robbie Stadium (2-1) | 26-22 | Won 2 |
| » W: Pete Harnisch (5-2) L: Luis Aquino (2-3) S: Doug Jones (11) | Third | 5½ out |
| Monday, May 31 |
| » Defeated Expos (27-22), 2-1 | Astrodome (15-12) | 27-22 | Won 3 |
| » W: Doug Jones (2-4) L: Mel Rojas (1-3) | Third | 5 out |
| Tuesday, June 1 |
| » Lost to Expos (28-22), 2-1 | Astrodome (15-13) | 27-23 | |
| » W: John Wetteland (3-0) L: Doug Drabek (5-6) | Third | 5½ out |
| Wednesday, June 2 |
| » Defeated Expos (28-23), 5-4 | Astrodome (16-13) | 28-23 | |
| » W: Doug Jones (3-4) L: Mel Rojas (1-4) | Third | 5½ out |
| Friday, June 4 |
| » Defeated Mets (18-33), 7-2 | Astrodome (17-13) | 29-23 | Won 2 |
| » W: Pete Harnisch (6-2) L: Frank Tanana (3-4) | Second | 4 out |
| Saturday, June 5 |
| » Defeated Mets (18-34), 7-5 | Astrodome (18-13) | 30-23 | Won 3 |
| » W: Darryl Kile (4-1) L: Mike Maddux (0-5) S: Xavier Hernandez (2) | Second | 4 out |
| Sunday, June 6 |
| » Defeated Mets (18-35), 5-4 | Astrodome (19-13) | 31-23 | Won 4 |
| » W: Al Osuna (1-0) L: Pete Schourek (2-7) S: Doug Jones (12) | Second | 4 out |
| Monday, June 7 |
| » Lost to Phillies (39-16), 7-5 | Veteran's Stadium (0-1) | 31-24 | |
| » W: Danny Jackson (5-2) L: Greg Swindell (5-5) S: Mitch Williams (17) | Second | 4½ out |
| Tuesday, June 8 |
| » Defeated Phillies (39-17), 6-3 | Veteran's Stadium (1-1) | 32-24 | |
| » W: Darryl Kile (5-1) L: Ben Rivera (4-3) S: Doug Jones (13) | Second | 3½ out |
| Wednesday, June 9 |
| » Lost to Phillies (40-17), 8-0 | Veteran's Stadium (1-2) | 32-25 | |
| » W: Terry Mulholland (7-5) L: Pete Harnisch (6-3) | Second | 4½ out |
| Friday, June 11 |
| » Lost to Rockies (18-41), 5-4 | Mile High Stadium (0-1) | 32-26 | Lost 2 |
| » W: Jeff Parrett (1-2) L: Xavier Hernandez (2-2) S: Darren Holmes (4) | Second | 5½ out |
| Saturday, June 12 |
| » Lost to Rockies (19-41), 14-11 | Mile High Stadium (0-2) | 32-27 | Lost 3 |
| » W: Keith Shepherd (1-0) L: Doug Jones (3-5) | Second | 6½ out |
| Sunday, June 13 |
| » Lost to Rockies (20-41), 9-1 | Mile High Stadium (0-3) | 32-28 | Lost 4 |
| » W: Bruce Ruffin (3-2) L: Greg Swindell (5-6) | Third | 7½ out |
| Tuesday, June 15 |
| » Lost to Padres (26-37), 3-0 | Astrodome (19-14) | 32-29 | Lost 5 |
| » W: Wally Whitehurst (2-3) L: Pete Harnisch (6-4) S: Gene Harris (10) | Fourth | 7½ out |
| Wednesday, June 16 |
| » Defeated Padres (26-38), 5-4 | Astrodome (20-14) | 33-29 | |
| » W: Mark Portugal (5-2) L: Doug Brocail (1-2) S: Al Osuna (1) | Fourth | 7½ out |
| Thursday, June 17 |
| » Defeated Padres (26-39), 4-1 | Astrodome (21-14) | 34-29 | Won 2 |
| » W: Darryl Kile (6-1) L: Andy Benes (7-6) S: Brian Williams (2) | Third | 7½ out |
| Friday, June 18 |
| » Lost to Giants (44-23), 5-0 | Astrodome (21-15) | 34-30 | |
| » W: Bud Black (6-1) L: Doug Drabek (5-7) | Third | 8½ out |
| Saturday, June 19 |
| » Lost to Giants (45-23), 10-3 | Astrodome (21-16) | 34-31 | Lost 2 |
| » W: John Burkett (10-2) L: Greg Swindell (5-7) | Third | 9½ out |
| Sunday, June 20 |
| » Lost to Giants (46-23), 8-5 | Astrodome (21-17) | 34-32 | Lost 3 |
| » W: Jeff Brantley (4-5) L: Brian Williams (1-2) S: Rod Beck (21) | Fourth | 10½ out |
| Monday, June 21 |
| » Lost to Dodgers (36-31), 7-0 | Dodger Stadium (0-1) | 34-33 | Lost 4 |
| » W: Ramon Martinez (6-4) L: Mark Portugal (5-3) | Fourth | 11½ out |
| Tuesday, June 22 |
| » Defeated Dodgers (36-32), 5-1 | Dodger Stadium (1-1) | 35-33 | |
| » W: Darryl Kile (7-1) L: Kevin Gross (5-6) | Fourth | 10½ out |
| Wednesday, June 23 |
| » Defeated Dodgers (36-33), 5-3 | Dodger Stadium (2-1) | 36-33 | Won 2 |
| » W: Doug Drabek (6-7) L: Jim Gott (2-4) S: Brian Williams (3) | Third | 10½ out |
| Thursday, June 24 |
| » Defeated Dodgers (36-34), 1-0 | Dodger Stadium (3-1) | 37-33 | Won 3 |
| » W: Greg Swindell (6-7) L: Orel Hershiser (6-6) S: Al Osuna (2) | Third | 10½ out |
| Friday, June 25 |
| » Lost to Braves (41-33), 8-2 | Atlanta-Fulton County Stadium (0-1) | 37-34 | |
| » W: Steve Avery (9-2) L: Pete Harnisch (6-5) | Third | 11½ out |
| Saturday, June 26 |
| » Lost to Braves (42-33), 6-5 | Atlanta-Fulton County Stadium (0-2) | 37-35 | Lost 2 |
| » W: Mike Stanton (3-2) L: Doug Jones (3-6) | Third | 11½ out |
| Sunday, June 27 |
| » Defeated Braves (42-34), 3-0 | Atlanta-Fulton County Stadium (1-2) | 38-35 | |
| » W: Darryl Kile (8-1) L: Greg Maddux (7-6) S: Xavier Hernandez (3) | Third | 11½ out |
| Tuesday, June 29 |
| » Lost to Reds (37-40), 3-0 | Riverfront Stadium (0-1) | 38-36 | |
| » W: Tom Browning (5-3) L: Doug Drabek (6-8) S: Rob Dibble (8) | Fourth | 12 out |
| Wednesday, June 30 |
| » Lost to Reds (38-40), 5-4 | Riverfront Stadium (0-2) | 38-37 | Lost 2 |
| » W: Jeff Reardon (2-1) L: Al Osuna (1-1) | Fourth | 12 out |
| Thursday, July 1 |
| » Defeated Reds (38-41), 8-1 | Riverfront Stadium (1-2) | 39-37 | |
| » W: Pete Harnisch (7-5) L: Jose Rijo (6-4) | Fourth | 11½ out |
| Friday, July 2 |
| » Defeated Cardinals (46-32), 7-1 | Astrodome (22-17) | 40-37 | Won 2 |
| » W: Mark Portugal (6-3) L: Joe Magrane (7-7) | Fourth | 11½ out |
| Saturday, July 3 |
| » Defeated Cardinals (46-33), 6-0 | Astrodome (23-17) | 41-37 | Won 3 |
| » W: Darryl Kile (9-1) L: Rheal Cormier (5-5) | Third | 10½ out |
| Sunday, July 4 |
| » Defeated Cardinals (46-34), 9-4 | Astrodome (24-17) | 42-37 | Won 4 |
| » W: Doug Drabek (7-8) L: Rene Arocha (6-3) | Third | 10½ out |
| Monday, July 5 |
| » Lost to Cardinals (47-34), 10-4 | Astrodome (24-18) | 42-38 | |
| » W: Donovan Osborne (7-3) L: Greg Swindell (6-8) | Third | 11½ out |
| Tuesday, July 6 |
| » Lost to Pirates (39-44), 10-3 | Astrodome (24-19) | 42-39 | Lost 2 |
| » W: Jeff Ballard (1-0) L: Pete Harnisch (7-6) | Fourth | 12½ out |
| Wednesday, July 7 |
| » Lost to Pirates (40-44), 5-2 | Astrodome (24-20) | 42-40 | Lost 3 |
| » W: Paul Wagner (4-5) L: Mark Portugal (6-4) S: Stan Belinda (16) | Fourth | 12½ out |
| » Major-league debuts: Todd Jones (Astros) |
| Thursday, July 8 |
| » Defeated Pirates (40-45), 10-4 | Astrodome (25-20) | 43-40 | |
| » W: Darryl Kile (10-1) L: Zane Smith (0-3) | Fourth | 12½ out |
| Friday, July 9 |
| » Lost to Cubs (41-42), 5-2 | Wrigley Field (1-2) | 43-41 | |
| » W: Mike Morgan (6-9) L: Doug Drabek (7-9) S: Randy Myers (27) | Fourth | 13½ out |
| Saturday, July 10 |
| » Defeated Cubs (41-43), 4-0 | Wrigley Field (2-2) | 44-41 | |
| » W: Pete Harnisch (8-6) L: Mike Harkey (6-3) | Third | 12 out |
| » Defeated Cubs (41-44), 5-2 | Wrigley Field (3-2) | 45-41 | Won 2 |
| » W: Brian Williams (2-2) L: Jose Guzman (7-7) S: Xavier Hernandez (4) | Third | 12 out |
| Sunday, July 11 |
| » Defeated Cubs (41-45), 10-1 | Wrigley Field (4-2) | 46-41 | Won 3 |
| » W: Mark Portugal (7-4) L: Greg Hibbard (7-6) | Third | 12 out |
| Thursday, July 15 |
| » Lost to Cardinals (52-36), 4-2 | Busch Stadium II (1-2) | 46-42 | |
| » W: Rene Arocha (7-3) L: Doug Drabek (7-10) S: Lee Smith (31) | Fourth | 13 out |
| Friday, July 16 |
| » Defeated Cardinals (52-37), 7-6 | Busch Stadium II (2-2) | 47-42 | |
| » W: Tom Edens (1-1) L: Lee Guetterman (1-1) S: Doug Jones (14) | Fourth | 13 out |
| Saturday, July 17 |
| » Lost to Cardinals (53-37), 5-3 | Busch Stadium II (2-3) | 47-43 | |
| » W: Bob Tewksbury (10-7) L: Brian Williams (2-3) S: Lee Smith (32) | Fourth | 13 out |
| Sunday, July 18 |
| » Lost to Cardinals (54-37), 7-6 | Busch Stadium II (2-4) | 47-44 | Lost 2 |
| » W: Lee Guetterman (2-1) L: Doug Jones (3-7) | Fourth | 13 out |
| Monday, July 19 |
| » Defeated Pirates (43-50), 4-2 | Three Rivers Stadium (3-1) | 48-44 | |
| » W: Pete Harnisch (9-6) L: Bob Walk (10-7) S: Doug Jones (15) | Fourth | 13 out |
| Tuesday, July 20 |
| » Lost to Pirates (44-50), 2-1 | Three Rivers Stadium (3-2) | 48-45 | |
| » W: Randy Tomlin (3-6) L: Doug Drabek (7-11) | Fourth | 14 out |
| Wednesday, July 21 |
| » Defeated Pirates (44-51), 5-3 | Three Rivers Stadium (4-2) | 49-45 | |
| » W: Darryl Kile (11-1) L: Steve Cooke (5-6) S: Doug Jones (16) | Third | 14 out |
| Thursday, July 22 |
| » Defeated Cubs (47-47), 9-4 | Astrodome (26-20) | 50-45 | Won 2 |
| » W: Brian Williams (3-3) L: Mike Harkey (7-4) | Third | 14 out |
| Friday, July 23 |
| » Defeated Cubs (47-48), 5-1 | Astrodome (27-20) | 51-45 | Won 3 |
| » W: Mark Portugal (8-4) L: Greg Hibbard (8-7) S: Doug Jones (17) | Third | 13 out |
| Saturday, July 24 |
| » Lost to Cubs (48-48), 7-6 | Astrodome (27-21) | 51-46 | |
| » W: Frank Castillo (4-6) L: Pete Harnisch (9-7) | Third | 14 out |
| Sunday, July 25 |
| » Lost to Cubs (49-48), 3-1 | Astrodome (27-22) | 51-47 | Lost 2 |
| » W: Bob Scanlan (2-4) L: Doug Jones (3-8) S: Randy Myers (30) | Third | 15 out |
| Monday, July 26 |
| » Lost to Reds (52-50), 6-1 | Astrodome (27-23) | 51-48 | Lost 3 |
| » W: Jose Rijo (8-5) L: Darryl Kile (11-2) | Fourth | 15 out |
| Tuesday, July 27 |
| » Defeated Reds (52-51), 6-5 | Astrodome (28-23) | 52-48 | |
| » W: Brian Williams (4-3) L: Tom Browning (7-6) S: Doug Jones (18) | Third | 15 out |
| Wednesday, July 28 |
| » Defeated Reds (52-52), 4-2 | Astrodome (29-23) | 53-48 | Won 2 |
| » W: Mark Portugal (9-4) L: Tim Pugh (6-10) S: Xavier Hernandez (5) | Third | 14 out |
| Thursday, July 29 |
| » Defeated Braves (61-43), 2-0 | Astrodome (30-23) | 54-48 | Won 3 |
| » W: Pete Harnisch (10-7) L: Kent Mercker (2-1) | Third | 13½ out |
| Friday, July 30 |
| » Lost to Braves (62-43), 4-1 | Astrodome (30-24) | 54-49 | |
| » W: Tom Glavine (13-4) L: Doug Drabek (7-12) S: Greg McMichael (2) | Third | 14½ out |
| Saturday, July 31 |
| » Lost to Braves (63-43), 4-3 | Astrodome (30-25) | 54-50 | Lost 2 |
| » W: Greg Maddux (12-8) L: Darryl Kile (11-3) S: Mike Stanton (27) | Fourth | 15½ out |
| Sunday, August 1 |
| » Lost to Braves (64-43), 3-2 | Astrodome (30-26) | 54-51 | Lost 3 |
| » W: John Smoltz (10-8) L: Greg Swindell (6-9) S: Greg McMichael (3) | Fourth | 16½ out |
| Tuesday, August 3 |
| » Defeated Dodgers (54-51), 6-1 | Astrodome (31-26) | 55-51 | |
| » W: Mark Portugal (10-4) L: Kevin Gross (7-10) S: Xavier Hernandez (6) | Third | 16½ out |
| Wednesday, August 4 |
| » Lost to Dodgers (55-51), 4-2 | Astrodome (31-27) | 55-52 | |
| » W: Tom Candiotti (7-5) L: Pete Harnisch (10-8) S: Jim Gott (19) | Fourth | 16½ out |
| Thursday, August 5 |
| » Lost to Dodgers (56-51), 5-2 | Astrodome (31-28) | 55-53 | Lost 2 |
| » W: Pedro Astacio (8-6) L: Doug Drabek (7-13) S: Jim Gott (20) | Fifth | 17½ out |
| Friday, August 6 |
| » Lost to Giants (74-36), 4-3 | Candlestick Park (0-4) | 55-54 | Lost 3 |
| » W: John Burkett (17-4) L: Darryl Kile (11-4) S: Rod Beck (33) | Fifth | 18½ out |
| Saturday, August 7 |
| » Defeated Giants (74-37), 6-5 | Candlestick Park (1-4) | 56-54 | |
| » W: Greg Swindell (7-9) L: Scott Sanderson (7-12) S: Doug Jones (19) | Fifth | 17½ out |
| Sunday, August 8 |
| » Defeated Giants (74-38), 4-1 | Candlestick Park (2-4) | 57-54 | Won 2 |
| » W: Mark Portugal (11-4) L: Bryan Hickerson (5-4) S: Doug Jones (20) | Fifth | 16½ out |
| Monday, August 9 |
| » Defeated Padres (44-69), 5-4 | San Diego/Jack Murphy Stadium (2-2) | 58-54 | Won 3 |
| » W: Xavier Hernandez (3-2) L: Trevor Hoffman (3-4) S: Doug Jones (21) | Third | 16½ out |
| Tuesday, August 10 |
| » Lost to Padres (45-69), 7-2 | San Diego/Jack Murphy Stadium (2-3) | 58-55 | |
| » W: Andy Ashby (1-6) L: Doug Drabek (7-14) | Third | 17½ out |
| Wednesday, August 11 |
| » Defeated Padres (45-70), 9-6 | San Diego/Jack Murphy Stadium (3-3) | 59-55 | |
| » W: Darryl Kile (12-4) L: Andy Benes (13-8) S: Doug Jones (22) | Third | 17½ out |
| Thursday, August 12 |
| » Defeated Padres (45-71), 5-3 | San Diego/Jack Murphy Stadium (4-3) | 60-55 | Won 2 |
| » W: Greg Swindell (8-9) L: Trevor Hoffman (3-5) S: Doug Jones (23) | Third | 17 out |
| Friday, August 13 |
| » Lost to Rockies (42-74), 5-3 | Astrodome (31-29) | 60-56 | |
| » W: Gary Wayne (3-3) L: Doug Jones (3-9) S: Darren Holmes (13) | Third | 18 out |
| Saturday, August 14 |
| » Defeated Rockies (42-75), 9-0 | Astrodome (32-29) | 61-56 | |
| » W: Pete Harnisch (11-8) L: Greg Harris (10-12) | Third | 17 out |
| Sunday, August 15 |
| » Lost to Rockies (43-75), 4-3 | Astrodome (32-30) | 61-57 | |
| » W: Bruce Ruffin (4-4) L: Xavier Hernandez (3-3) S: Darren Holmes (14) | Third | 18 out |
| Tuesday, August 17 |
| » Defeated Marlins (51-68), 4-0 | Astrodome (33-30) | 62-57 | |
| » W: Darryl Kile (13-4) L: Pat Rapp (1-4) | Third | 17 out |
| Wednesday, August 18 |
| » Defeated Marlins (51-69), 2-1 | Astrodome (34-30) | 63-57 | Won 2 |
| » W: Greg Swindell (9-9) L: Joe Klink (0-2) S: Todd Jones (1) | Third | 17 out |
| Thursday, August 19 |
| » Defeated Marlins (51-70), 8-3 | Astrodome (35-30) | 64-57 | Won 3 |
| » W: Mark Portugal (12-4) L: Charlie Hough (7-13) | Third | 17 out |
| Friday, August 20 |
| » Lost to Phillies (78-44), 6-4 | Astrodome (35-31) | 64-58 | |
| » W: David West (6-3) L: Todd Jones (0-1) S: Mitch Williams (35) | Third | 17 out |
| Saturday, August 21 |
| » Defeated Phillies (78-45), 3-2 | Astrodome (36-31) | 65-58 | |
| » W: Doug Jones (4-9) L: Larry Andersen (3-2) | Third | 17 out |
| Sunday, August 22 |
| » Defeated Phillies (78-46), 7-3 | Astrodome (37-31) | 66-58 | Won 2 |
| » W: Darryl Kile (14-4) L: Ben Rivera (11-7) | Third | 17 out |
| Tuesday, August 24 |
| » Defeated Marlins (52-73), 4-0 | Joe Robbie Stadium (3-1) | 67-58 | Won 3 |
| » W: Greg Swindell (10-9) L: Jack Armstrong (7-13) | Third | 15½ out |
| Wednesday, August 25 |
| » Defeated Marlins (52-74), 3-2 | Joe Robbie Stadium (4-1) | 68-58 | Won 4 |
| » W: Mark Portugal (13-4) L: Charlie Hough (7-14) S: Xavier Hernandez (7) | Third | 14½ out |
| Thursday, August 26 |
| » Lost to Marlins (53-74), 5-4 | Joe Robbie Stadium (4-2) | 68-59 | |
| » W: Richie Lewis (6-1) L: Doug Jones (4-10) | Third | 15 out |
| Friday, August 27 |
| » Lost to Expos (69-60), 3-1 | Stade Olympique (2-2) | 68-60 | Lost 2 |
| » W: Dennis Martinez (12-8) L: Doug Drabek (7-15) S: John Wetteland (30) | Third | 15 out |
| Saturday, August 28 |
| » Lost to Expos (70-60), 7-3 | Stade Olympique (2-3) | 68-61 | Lost 3 |
| » W: Kirk Rueter (5-0) L: Darryl Kile (14-5) S: Mel Rojas (9) | Third | 15½ out |
| Sunday, August 29 |
| » Lost to Expos (71-60), 3-2 | Stade Olympique (2-4) | 68-62 | Lost 4 |
| » W: Ken Hill (8-5) L: Greg Swindell (10-10) S: John Wetteland (31) | Third | 16½ out |
| Monday, August 30 |
| » Lost to Mets (46-85), 5-4 | Shea Stadium (3-1) | 68-63 | Lost 5 |
| » W: Mike Maddux (3-6) L: Xavier Hernandez (3-4) S: John Franco (9) | Third | 17½ out |
| Tuesday, August 31 |
| » Defeated Mets (46-86), 10-2 | Shea Stadium (4-1) | 69-63 | |
| » W: Pete Harnisch (12-8) L: Dwight Gooden (12-15) | Third | 16½ out |
| Wednesday, September 1 |
| » Defeated Mets (46-87), 3-2 | Shea Stadium (5-1) | 70-63 | Won 2 |
| » W: Doug Drabek (8-15) L: Sid Fernandez (3-5) S: Doug Jones (24) | Third | 16½ out |
| Friday, September 3 |
| » Lost to Expos (75-60), 3-0 | Astrodome (37-32) | 70-64 | |
| » W: Kirk Rueter (6-0) L: Darryl Kile (14-6) S: John Wetteland (32) | Third | 17 out |
| Saturday, September 4 |
| » Lost to Expos (76-60), 7-5 | Astrodome (37-33) | 70-65 | Lost 2 |
| » W: Ken Hill (9-5) L: Greg Swindell (10-11) S: John Wetteland (33) | Third | 18 out |
| Sunday, September 5 |
| » Defeated Expos (76-61), 7-1 | Astrodome (38-33) | 71-65 | |
| » W: Mark Portugal (14-4) L: Jeff Fassero (10-4) | Third | 17 out |
| Monday, September 6 |
| » Defeated Mets (47-91), 7-2 | Astrodome (39-33) | 72-65 | Won 2 |
| » W: Pete Harnisch (13-8) L: Sid Fernandez (3-6) S: Xavier Hernandez (8) | Third | 17 out |
| » Major-league debuts: Tito Navarro (Mets) |
| Tuesday, September 7 |
| » Defeated Mets (47-92), 4-3 | Astrodome (40-33) | 73-65 | Won 3 |
| » W: Todd Jones (1-1) L: John Franco (3-3) | Third | 16 out |
| Wednesday, September 8 |
| » Defeated Mets (47-93), 7-1 | Astrodome (41-33) | 74-65 | Won 4 |
| » W: Darryl Kile (15-6) L: Frank Tanana (6-15) | Third | 15½ out |
| » Major-league debuts: Butch Huskey (Mets) |
| Friday, September 10 |
| » Lost to Phillies (87-54), 6-2 | Veteran's Stadium (1-3) | 74-66 | |
| » W: Curt Schilling (13-6) L: Greg Swindell (10-12) | Third | 15 out |
| Saturday, September 11 |
| » Defeated Phillies (87-55), 4-1 | Veteran's Stadium (2-3) | 75-66 | |
| » W: Mark Portugal (15-4) L: Mike Williams (1-2) S: Todd Jones (2) | Third | 15 out |
| Sunday, September 12 |
| » Defeated Phillies (87-56), 9-2 | Veteran's Stadium (3-3) | 76-66 | Won 2 |
| » W: Pete Harnisch (14-8) L: Ben Rivera (12-9) | Third | 14 out |
| » Major-league debuts: Kevin Foster (Phillies) |
| Tuesday, September 14 |
| » Lost to Rockies (57-88), 9-4 | Mile High Stadium (0-4) | 76-67 | |
| » W: Armando Reynoso (10-10) L: Doug Drabek (8-16) S: Bruce Ruffin (2) | Third | 15½ out |
| » Lost to Rockies (58-88), 6-5 | Mile High Stadium (0-5) | 76-68 | Lost 2 |
| » W: Darren Holmes (3-3) L: Xavier Hernandez (3-5) | Third | 15½ out |
| Wednesday, September 15 |
| » Lost to Rockies (59-88), 6-4 | Mile High Stadium (0-6) | 76-69 | Lost 3 |
| » W: Mike Munoz (2-2) L: Brian Williams (4-4) S: Darren Holmes (22) | Third | 16½ out |
| Thursday, September 16 |
| » Lost to Rockies (60-88), 6-3 | Mile High Stadium (0-7) | 76-70 | Lost 4 |
| » W: Bruce Ruffin (6-5) L: Todd Jones (1-2) S: Darren Holmes (23) | Third | 17½ out |
| Friday, September 17 |
| » Defeated Padres (57-91), 3-0 | Astrodome (42-33) | 77-70 | |
| » W: Pete Harnisch (15-8) L: Andy Benes (15-13) | Third | 17½ out |
| Saturday, September 18 |
| » Defeated Padres (57-92), 4-2 | Astrodome (43-33) | 78-70 | Won 2 |
| » W: Doug Drabek (9-16) L: Scott Sanders (3-2) | Third | 16½ out |
| Sunday, September 19 |
| » Lost to Padres (58-92), 6-3 | Astrodome (43-34) | 78-71 | |
| » W: Andy Ashby (3-9) L: Darryl Kile (15-7) S: Mark Davis (4) | Third | 17½ out |
| Monday, September 20 |
| » Lost to Giants (93-56), 7-2 | Astrodome (43-35) | 78-72 | Lost 2 |
| » W: Jim Deshaies (13-15) L: Greg Swindell (10-13) | Third | 18 out |
| Tuesday, September 21 |
| » Defeated Giants (93-57), 6-0 | Astrodome (44-35) | 79-72 | |
| » W: Mark Portugal (16-4) L: Salomon Torres (2-3) | Third | 18 out |
| Wednesday, September 22 |
| » Lost to Giants (94-57), 1-0 | Astrodome (44-36) | 79-73 | |
| » W: Bill Swift (19-8) L: Pete Harnisch (15-9) S: Rod Beck (42) | Third | 18 out |
| Thursday, September 23 |
| » Lost to Giants (95-57), 7-0 | Astrodome (44-37) | 79-74 | Lost 2 |
| » W: John Burkett (20-7) L: Doug Drabek (9-17) | Third | 19 out |
| Friday, September 24 |
| » Lost to Dodgers (79-74), 6-3 | Dodger Stadium (3-2) | 79-75 | Lost 3 |
| » W: Pedro Astacio (14-8) L: Darryl Kile (15-8) | Fourth | 19 out |
| Saturday, September 25 |
| » Defeated Dodgers (79-75), 12-4 | Dodger Stadium (4-2) | 80-75 | |
| » W: Greg Swindell (11-13) L: Pedro Martinez (10-5) | Third | 19 out |
| Sunday, September 26 |
| » Defeated Dodgers (79-76), 5-4 | Dodger Stadium (5-2) | 81-75 | Won 2 |
| » W: Mark Portugal (17-4) L: Ramon Martinez (10-11) S: Doug Jones (25) | Third | 19 out |
| Tuesday, September 28 |
| » Defeated Braves (100-57), 5-2 | Atlanta-Fulton County Stadium (2-2) | 82-75 | Won 3 |
| » W: Pete Harnisch (16-9) L: Greg Maddux (19-10) S: Doug Jones (26) | Second | 18 out |
| Wednesday, September 29 |
| » Lost to Braves (101-57), 6-3 | Atlanta-Fulton County Stadium (2-3) | 82-76 | |
| » W: Tom Glavine (21-6) L: Doug Drabek (9-18) S: Greg McMichael (17) | Third | 19 out |
| Thursday, September 30 |
| » Defeated Braves (101-58), 10-8 | Atlanta-Fulton County Stadium (3-3) | 83-76 | |
| » W: Xavier Hernandez (4-5) L: John Smoltz (15-11) | Second | 18 out |
| Friday, October 1 |
| » Defeated Reds (72-88), 2-0 | Riverfront Stadium (2-2) | 84-76 | Won 2 |
| » W: Greg Swindell (12-13) L: Jose Rijo (14-9) | Second | 18 out |
| Saturday, October 2 |
| » Defeated Reds (72-89), 3-1 | Riverfront Stadium (3-2) | 85-76 | Won 3 |
| » W: Mark Portugal (18-4) L: Ross Powell (0-3) S: Xavier Hernandez (9) | Second | 18 out |
| Sunday, October 3 |
| » Lost to Reds (73-89), 7-4 | Riverfront Stadium (3-3) | 85-77 | |
| » W: Bobby Ayala (7-10) L: Jeff Juden (0-1) S: Scott Service (2) | Third | 19 out |
Game information provided by Retrosheet (www.retrosheet.org) |