| Saturday, February 8 |
| Former Red Sox Fabian Gaffke dies in Milwaukee, WI at the age of 79. |
| Thursday, April 2 |
| Former Red Sox Dib Williams dies in Searcy, AR at the age of 83. |
| Tuesday, April 7 |
| » Lost to Yankees (1-0), 4-3 | Yankee Stadium (0-1) | 0-1 | |
| » W: Scott Sanderson (1-0) L: Roger Clemens (0-1) S: Steve Farr (1) | Second | 1 out |
| Wednesday, April 8 |
| » Major-league debuts: Chad Curtis (Angels) |
| Thursday, April 9 |
| » Lost to Yankees (2-0), 3-2 | Yankee Stadium (0-2) | 0-2 | Lost 2 |
| » W: Rich Monteleone (1-0) L: Frank Viola (0-1) S: Steve Howe (1) | Fifth | 2½ out |
| Saturday, April 11 |
| » Defeated Indians (1-3), 7-5 | Cleveland Stadium (1-0) | 1-2 | |
| » W: Mike Gardiner (1-0) L: Eric Bell (0-1) | Fourth | 3 out |
| » Major-league debuts: Peter Hoy (Red Sox) |
| Sunday, April 12 |
| » Lost to Indians (2-3), 2-1 | Cleveland Stadium (1-1) | 1-3 | |
| » W: Charles Nagy (1-1) L: Matt Young (0-1) S: Derek Lilliquist (1) | Third | 3½ out |
| » Defeated Indians (2-4), 3-0 | Cleveland Stadium (2-1) | 2-3 | |
| » W: Roger Clemens (1-1) L: Scott Scudder (0-1) | Third | 3½ out |
| » Major-league debuts: John Flaherty (Red Sox) |
| Monday, April 13 |
| » Lost to Orioles (3-4), 8-6 | Fenway Park (0-1) | 2-4 | |
| » W: Todd Frohwirth (1-0) L: Tony Fossas (0-1) S: Gregg Olson (1) | Fourth | 4 out |
| Wednesday, April 15 |
| » Defeated Orioles (3-5), 6-5 | Fenway Park (1-1) | 3-4 | |
| » W: Greg Harris (1-0) L: Storm Davis (0-1) S: Jeff Reardon (1) | Fourth | 4 out |
| Friday, April 17 |
| » Defeated Blue Jays (9-2), 1-0 | Fenway Park (2-1) | 4-4 | Won 2 |
| » W: Roger Clemens (2-1) L: David Wells (1-1) S: Jeff Reardon (2) | Fourth | 3½ out |
| Saturday, April 18 |
| » Lost to Blue Jays (10-2), 2-1 | Fenway Park (2-2) | 4-5 | |
| » W: Todd Stottlemyre (1-1) L: Frank Viola (0-2) S: Tom Henke (2) | Fourth | 4½ out |
| Sunday, April 19 |
| » Defeated Blue Jays (10-3), 5-4 | Fenway Park (3-2) | 5-5 | |
| » W: Danny Darwin (1-0) L: Tom Henke (1-1) | Fourth | 3½ out |
| Monday, April 20 |
| » Lost to Blue Jays (11-3), 6-4 | Fenway Park (3-3) | 5-6 | |
| » W: Rob MacDonald (1-0) L: Tom Bolton (0-1) | Fourth | 4½ out |
| Tuesday, April 21 |
| » Defeated Brewers (5-7), 3-1 | County Stadium (1-0) | 6-6 | |
| » W: Mike Gardiner (2-0) L: Jim Austin (1-1) S: Danny Darwin (1) | Fourth | 4½ out |
| Thursday, April 23 |
| » Lost to Brewers (6-7), 3-2 | County Stadium (1-1) | 6-7 | |
| » W: Bill Wegman (2-1) L: Roger Clemens (2-2) S: Doug Henry (2) | Third | 5 out |
| Former Red Sox Deron Johnson dies at the age of 54. |
| Friday, April 24 |
| » Defeated Rangers (9-9), 3-1 | Fenway Park (4-3) | 7-7 | |
| » W: Frank Viola (1-2) L: Jose Guzman (1-2) | Fourth | 5 out |
| Sunday, April 26 |
| » Lost to Rangers (10-9), 3-1 | Fenway Park (4-4) | 7-8 | |
| » W: Bobby Witt (2-2) L: Matt Young (0-2) S: Jeff Russell (4) | Fifth | 6 out |
| » Lost to Rangers (11-9), 4-2 | Fenway Park (4-5) | 7-9 | Lost 2 |
| » W: Terry Mathews (1-1) L: Greg Harris (1-1) S: Jeff Russell (5) | Fifth | 6 out |
| Monday, April 27 |
| » Major-league debuts: Dave Silvestri (Yankees) |
| Tuesday, April 28 |
| » Defeated White Sox (10-7), 6-3 | Fenway Park (5-5) | 8-9 | |
| » W: Roger Clemens (3-2) L: Kirk McCaskill (1-3) S: Jeff Reardon (3) | Fourth | 5 out |
| Wednesday, April 29 |
| » Defeated White Sox (10-8), 6-1 | Fenway Park (6-5) | 9-9 | Won 2 |
| » W: Frank Viola (2-2) L: Alex Fernandez (1-2) S: Jeff Reardon (4) | Third | 5 out |
| Friday, May 1 |
| » Defeated Royals (3-18), 6-5 | Fenway Park (7-5) | 10-9 | Won 3 |
| » W: Danny Darwin (2-0) L: Jeff Montgomery (0-3) | Fourth | 3½ out |
| Saturday, May 2 |
| » Defeated Royals (3-19), 7-6 | Fenway Park (8-5) | 11-9 | Won 4 |
| » W: Greg Harris (2-1) L: Hipolito Pichardo (0-1) S: Jeff Reardon (5) | Fifth | 2½ out |
| Sunday, May 3 |
| » Lost to Royals (4-19), 5-2 | Fenway Park (8-6) | 11-10 | |
| » W: Kevin Appier (1-2) L: Joe Hesketh (0-1) S: Jeff Montgomery (3) | Fifth | 3½ out |
| Monday, May 4 |
| » Lost to Twins (12-13), 6-1 | Fenway Park (8-7) | 11-11 | Lost 2 |
| » W: John Smiley (1-2) L: Roger Clemens (3-3) | Fifth | 4½ out |
| Tuesday, May 5 |
| » Defeated Twins (12-14), 4-1 | Fenway Park (9-7) | 12-11 | |
| » W: Frank Viola (3-2) L: Pat Mahomes (2-1) S: Jeff Reardon (6) | Fourth | 4½ out |
| Wednesday, May 6 |
| » Lost to White Sox (15-10), 7-5 | Comiskey Park II (0-1) | 12-12 | |
| » W: Scott Radinsky (2-1) L: Danny Darwin (2-1) S: Bobby Thigpen (6) | Fourth | 5½ out |
| Thursday, May 7 |
| » Lost to White Sox (16-10), 7-6 | Comiskey Park II (0-2) | 12-13 | Lost 2 |
| » W: Donn Pall (1-0) L: Greg Harris (2-2) S: Bobby Thigpen (7) | Fourth | 6½ out |
| Friday, May 8 |
| » Lost to Royals (8-20), 2-1 | Royals Stadium (0-1) | 12-14 | Lost 3 |
| » W: Kevin Appier (2-2) L: Joe Hesketh (0-2) S: Jeff Montgomery (6) | Fourth | 6½ out |
| Saturday, May 9 |
| » Defeated Royals (8-21), 5-0 | Royals Stadium (1-1) | 13-14 | |
| » W: Roger Clemens (4-3) L: Tom Gordon (0-4) | Fourth | 5½ out |
| Sunday, May 10 |
| » Defeated Royals (8-22), 10-6 | Royals Stadium (2-1) | 14-14 | Won 2 |
| » W: Frank Viola (4-2) L: Mike Magnante (0-3) | Third | 5½ out |
| Tuesday, May 12 |
| » Lost to Twins (16-16), 6-3 | Hubert H. Humphrey Metrodome (0-1) | 14-15 | |
| » W: Kevin Tapani (2-4) L: Mike Gardiner (2-1) S: Rick Aguilera (10) | Fourth | 6½ out |
| » Major-league debuts: Jeff Reboulet (Twins) |
| Wednesday, May 13 |
| » Lost to Twins (17-16), 4-3 | Hubert H. Humphrey Metrodome (0-2) | 14-16 | Lost 2 |
| » W: Tom Edens (2-0) L: Greg Harris (2-3) | Fourth | 7½ out |
| Friday, May 15 |
| » Defeated Angels (18-16), 3-0 | Fenway Park (10-7) | 15-16 | |
| » W: Roger Clemens (5-3) L: Jim Abbott (2-5) | Fourth | 7 out |
| Saturday, May 16 |
| » Defeated Angels (18-17), 3-0 | Fenway Park (11-7) | 16-16 | Won 2 |
| » W: Frank Viola (5-2) L: Julio Valera (2-2) S: Jeff Reardon (7) | Fourth | 6½ out |
| Sunday, May 17 |
| » Lost to Angels (19-17), 3-1 | Fenway Park (11-8) | 16-17 | |
| » W: Mark Langston (4-1) L: John Dopson (0-1) S: Bryan Harvey (12) | Fourth | 6½ out |
| Monday, May 18 |
| » Defeated Mariners (15-23), 3-2 | Fenway Park (12-8) | 17-17 | |
| » W: Mike Gardiner (3-1) L: Erik Hanson (1-6) S: Jeff Reardon (8) | Fourth | 5½ out |
| Tuesday, May 19 |
| » Defeated Mariners (15-24), 7-5 | Fenway Park (13-8) | 18-17 | Won 2 |
| » W: Tom Bolton (1-1) L: Jeff Nelson (0-2) S: Jeff Reardon (9) | Fourth | 4½ out |
| Wednesday, May 20 |
| » Defeated Mariners (15-25), 6-4 | Fenway Park (14-8) | 19-17 | Won 3 |
| » W: Roger Clemens (6-3) L: Dennis Powell (1-1) S: Jeff Reardon (10) | Fourth | 4 out |
| Friday, May 22 |
| » Lost to Athletics (25-16), 5-3 | Fenway Park (14-9) | 19-18 | |
| » W: Dave Stewart (3-4) L: Frank Viola (5-3) S: Dennis Eckersley (17) | Fourth | 5 out |
| Saturday, May 23 |
| » Defeated Athletics (25-17), 5-1 | Fenway Park (15-9) | 20-18 | |
| » W: John Dopson (1-1) L: Mike Moore (5-3) | Fourth | 4 out |
| Sunday, May 24 |
| » Lost to Athletics (26-17), 4-0 | Fenway Park (15-10) | 20-19 | |
| » W: Ron Darling (4-2) L: Mike Gardiner (3-2) | Fourth | 4½ out |
| Tuesday, May 26 |
| » Defeated Angels (20-23), 4-1 | Anaheim Stadium (1-0) | 21-19 | |
| » W: Roger Clemens (7-3) L: Jim Abbott (2-6) S: Jeff Reardon (11) | Fourth | 4 out |
| Wednesday, May 27 |
| » Defeated Angels (20-24), 4-3 | Anaheim Stadium (2-0) | 22-19 | Won 2 |
| » W: Jeff Reardon (1-0) L: Bryan Harvey (0-3) S: Danny Darwin (2) | Fourth | 3 out |
| Thursday, May 28 |
| » Defeated Angels (20-25), 2-1 | Anaheim Stadium (3-0) | 23-19 | Won 3 |
| » W: Joe Hesketh (1-2) L: Mark Langston (5-2) S: Jeff Reardon (12) | Fourth | 2½ out |
| Former Red Sox Charley Schanz dies in Sacramento, CA at the age of 73. |
| Friday, May 29 |
| » Lost to Mariners (20-27), 7-3 | Kingdome (0-1) | 23-20 | |
| » W: Dennis Powell (2-1) L: John Dopson (1-2) | Fourth | 3½ out |
| Saturday, May 30 |
| » Lost to Mariners (21-27), 3-0 | Kingdome (0-2) | 23-21 | Lost 2 |
| » W: Dave Fleming (7-1) L: Mike Gardiner (3-3) | Fourth | 4½ out |
| Sunday, May 31 |
| » Defeated Mariners (21-28), 7-1 | Kingdome (1-2) | 24-21 | |
| » W: Roger Clemens (8-3) L: Randy Johnson (5-5) | Fourth | 4½ out |
| Monday, June 1 |
| » Lost to Athletics (28-22), 10-7 | Oakland-Alameda County Stadium (0-1) | 24-22 | |
| » W: Kevin Campbell (1-0) L: Danny Darwin (2-2) | Fourth | 5½ out |
| Tuesday, June 2 |
| » Lost to Athletics (29-22), 5-4 | Oakland-Alameda County Stadium (0-2) | 24-23 | Lost 2 |
| » W: Mike Moore (7-3) L: Joe Hesketh (1-3) S: Dennis Eckersley (19) | Fourth | 6½ out |
| Wednesday, June 3 |
| » Lost to Athletics (30-22), 7-6 | Oakland-Alameda County Stadium (0-3) | 24-24 | Lost 3 |
| » W: Jeff Parrett (5-0) L: Mike Gardiner (3-4) S: Dennis Eckersley (20) | Fourth | 6½ out |
| Saturday, June 6 |
| » Defeated Indians (21-33), 5-1 | Fenway Park (16-10) | 25-24 | |
| » W: Roger Clemens (9-3) L: Jack Armstrong (1-7) | Fifth | 6½ out |
| » Lost to Indians (22-33), 3-1 | Fenway Park (16-11) | 25-25 | |
| » W: Charles Nagy (7-3) L: Frank Viola (5-4) S: Steve Olin (12) | Fifth | 6½ out |
| Sunday, June 7 |
| » Defeated Indians (22-34), 4-0 | Fenway Park (17-11) | 26-25 | |
| » W: Joe Hesketh (2-3) L: Dave Otto (4-4) S: Danny Darwin (3) | Fifth | 5½ out |
| Monday, June 8 |
| » Lost to Orioles (34-21), 5-2 | Oriole Park at Camden Yards (0-1) | 26-26 | |
| » W: Bob Milacki (5-3) L: Mike Gardiner (3-5) S: Gregg Olson (15) | Fifth | 6½ out |
| Tuesday, June 9 |
| » Defeated Orioles (34-22), 4-1 | Oriole Park at Camden Yards (1-1) | 27-26 | |
| » W: John Dopson (2-2) L: Jose Mesa (2-6) S: Jeff Reardon (13) | Fourth | 6½ out |
| Wednesday, June 10 |
| » Lost to Orioles (35-22), 3-1 | Oriole Park at Camden Yards (1-2) | 27-27 | |
| » W: Rick Sutcliffe (9-4) L: Tom Bolton (1-2) S: Gregg Olson (16) | Fourth | 7½ out |
| Thursday, June 11 |
| » Lost to Blue Jays (38-22), 4-0 | Skydome (0-1) | 27-28 | Lost 2 |
| » W: Jack Morris (7-3) L: Roger Clemens (9-4) | Fourth | 8½ out |
| Friday, June 12 |
| » Defeated Blue Jays (38-23), 5-0 | Skydome (1-1) | 28-28 | |
| » W: Frank Viola (6-4) L: Dave Stieb (3-6) | Fourth | 7½ out |
| Saturday, June 13 |
| » Defeated Blue Jays (38-24), 5-3 | Skydome (2-1) | 29-28 | Won 2 |
| » W: Joe Hesketh (3-3) L: Todd Stottlemyre (5-5) S: Jeff Reardon (14) | Fourth | 6½ out |
| Sunday, June 14 |
| » Lost to Blue Jays (39-24), 6-2 | Skydome (2-2) | 29-29 | |
| » W: Juan Guzman (8-1) L: Mike Gardiner (3-6) S: Duane Ward (7) | Fourth | 7½ out |
| Monday, June 15 |
| » Defeated Yankees (30-31), 1-0 | Fenway Park (18-11) | 30-29 | |
| » W: John Dopson (3-2) L: Scott Sanderson (4-5) S: Jeff Reardon (15) | Fourth | 7 out |
| Tuesday, June 16 |
| » Defeated Yankees (30-32), 4-3 | Fenway Park (19-11) | 31-29 | Won 2 |
| » W: Danny Darwin (3-2) L: Greg Cadaret (3-6) | Fourth | 6 out |
| Wednesday, June 17 |
| » Defeated Yankees (30-33), 4-3 | Fenway Park (20-11) | 32-29 | Won 3 |
| » W: Frank Viola (7-4) L: Scott Kamieniecki (1-5) S: Tony Fossas (1) | Fourth | 6 out |
| Thursday, June 18 |
| » Lost to Yankees (31-33), 5-4 | Fenway Park (20-12) | 32-30 | |
| » W: Melido Perez (7-4) L: Danny Darwin (3-3) S: Steve Farr (10) | Fourth | 6 out |
| Friday, June 19 |
| » Lost to Rangers (37-32), 4-1 | Arlington Stadium (0-1) | 32-31 | Lost 2 |
| » W: Bobby Witt (8-5) L: Mike Gardiner (3-7) S: Jeff Russell (18) | Fourth | 6 out |
| Saturday, June 20 |
| » Lost to Rangers (38-32), 4-1 | Arlington Stadium (0-2) | 32-32 | Lost 3 |
| » W: Kevin Brown (10-4) L: John Dopson (3-3) S: Kenny Rogers (4) | Fourth | 7 out |
| Sunday, June 21 |
| » Lost to Rangers (39-32), 3-2 | Arlington Stadium (0-3) | 32-33 | Lost 4 |
| » W: Todd Burns (2-0) L: Roger Clemens (9-5) S: Jeff Russell (19) | Fifth | 7 out |
| Monday, June 22 |
| » Lost to Tigers (31-38), 4-2 | Tiger Stadium (0-1) | 32-34 | Lost 5 |
| » W: Kurt Knudsen (2-0) L: Danny Darwin (3-4) | Fourth | 8 out |
| Tuesday, June 23 |
| » Lost to Tigers (32-38), 11-7 | Tiger Stadium (0-2) | 32-35 | Lost 6 |
| » W: John Kiely (1-0) L: Joe Hesketh (3-4) | Fourth | 8½ out |
| Wednesday, June 24 |
| » Lost to Tigers (33-38), 5-1 | Tiger Stadium (0-3) | 32-36 | Lost 7 |
| » W: Frank Tanana (6-5) L: Mike Gardiner (3-8) | Fifth | 9½ out |
| Friday, June 26 |
| » Defeated Brewers (37-33), 8-4 | Fenway Park (21-12) | 33-36 | |
| » W: John Dopson (4-3) L: Ron Robinson (1-3) | Fifth | 9½ out |
| Saturday, June 27 |
| » Defeated Brewers (37-34), 8-7 | Fenway Park (22-12) | 34-36 | Won 2 |
| » W: Danny Darwin (4-4) L: Darren Holmes (2-3) | Fifth | 8½ out |
| Sunday, June 28 |
| » Lost to Brewers (38-34), 9-3 | Fenway Park (22-13) | 34-37 | |
| » W: Jaime Navarro (8-6) L: Frank Viola (7-5) | Fifth | 8½ out |
| Monday, June 29 |
| » Lost to Tigers (35-41), 8-3 | Fenway Park (22-14) | 34-38 | Lost 2 |
| » W: Frank Tanana (7-5) L: Joe Hesketh (3-5) S: Kurt Knudsen (2) | Fifth | 9½ out |
| Tuesday, June 30 |
| » Defeated Tigers (35-42), 8-5 | Fenway Park (23-14) | 35-38 | |
| » W: Daryl Irvine (1-0) L: Mike Henneman (0-3) | Fifth | 8½ out |
| Wednesday, July 1 |
| » Defeated Tigers (35-43), 6-4 | Fenway Park (24-14) | 36-38 | Won 2 |
| » W: John Dopson (5-3) L: Bill Gullickson (9-5) S: Jeff Reardon (16) | Fifth | 8½ out |
| Thursday, July 2 |
| » Lost to White Sox (39-37), 8-3 | Comiskey Park II (0-3) | 36-39 | |
| » W: Wilson Alvarez (1-2) L: Roger Clemens (9-6) S: Roberto Hernandez (1) | Fifth | 9 out |
| Friday, July 3 |
| » Lost to White Sox (40-37), 2-1 | Comiskey Park II (0-4) | 36-40 | Lost 2 |
| » W: Bobby Thigpen (1-2) L: Greg Harris (2-4) | Fifth | 10 out |
| Saturday, July 4 |
| » Defeated White Sox (40-38), 2-1 | Comiskey Park II (1-4) | 37-40 | |
| » W: Joe Hesketh (4-5) L: Jack McDowell (11-4) S: Jeff Reardon (17) | Fifth | 10 out |
| Sunday, July 5 |
| » Lost to White Sox (41-38), 4-2 | Comiskey Park II (1-5) | 37-41 | |
| » W: Greg Hibbard (7-4) L: Mike Gardiner (3-9) S: Scott Radinsky (4) | Fifth | 11 out |
| Monday, July 6 |
| » Lost to Royals (34-47), 6-3 | Fenway Park (24-15) | 37-42 | Lost 2 |
| » W: Rick Reed (2-3) L: John Dopson (5-4) S: Rusty Meacham (1) | Fifth | 12 out |
| Tuesday, July 7 |
| » Defeated Royals (34-48), 3-2 | Fenway Park (25-15) | 38-42 | |
| » W: Danny Darwin (5-4) L: Rusty Meacham (4-2) | Fifth | 12 out |
| Wednesday, July 8 |
| » Defeated Royals (34-49), 5-4 | Fenway Park (26-15) | 39-42 | Won 2 |
| » W: Tony Fossas (1-1) L: Tom Gordon (1-9) S: Jeff Reardon (18) | Fifth | 12 out |
| Thursday, July 9 |
| » Lost to White Sox (43-40), 10-3 | Fenway Park (26-16) | 39-43 | |
| » W: Jack McDowell (12-4) L: Joe Hesketh (4-6) | Sixth | 13 out |
| Friday, July 10 |
| » Defeated White Sox (43-41), 6-5 | Fenway Park (27-16) | 40-43 | |
| » W: Jeff Reardon (2-0) L: Terry Leach (1-3) | Fifth | 12 out |
| Saturday, July 11 |
| » Defeated White Sox (43-42), 11-2 | Fenway Park (28-16) | 41-43 | Won 2 |
| » W: John Dopson (6-4) L: Kirk McCaskill (6-7) | Fourth | 11 out |
| Sunday, July 12 |
| » Defeated White Sox (43-43), 3-0 | Fenway Park (29-16) | 42-43 | Won 3 |
| » W: Frank Viola (8-5) L: Wilson Alvarez (2-3) S: Greg Harris (1) | Fourth | 10 out |
| Thursday, July 16 |
| » Lost to Twins (54-34), 7-6 | Hubert H. Humphrey Metrodome (0-3) | 42-44 | |
| » W: Carl Willis (4-2) L: Mike Gardiner (3-10) S: Rick Aguilera (27) | Fourth | 11 out |
| Friday, July 17 |
| » Lost to Twins (55-34), 3-2 | Hubert H. Humphrey Metrodome (0-4) | 42-45 | Lost 2 |
| » W: Bob Kipper (3-3) L: Greg Harris (2-5) | Fourth | 11 out |
| Saturday, July 18 |
| » Defeated Twins (55-35), 1-0 | Hubert H. Humphrey Metrodome (1-4) | 43-45 | |
| » W: Roger Clemens (10-6) L: Scott Erickson (6-7) | Fourth | 11 out |
| Sunday, July 19 |
| » Lost to Twins (56-35), 7-5 | Hubert H. Humphrey Metrodome (1-5) | 43-46 | |
| » W: Mark Guthrie (2-2) L: Greg Harris (2-6) S: Rick Aguilera (28) | Fourth | 12 out |
| Monday, July 20 |
| » Defeated Royals (40-52), 5-3 | Royals Stadium (3-1) | 44-46 | |
| » W: Paul Quantrill (1-0) L: Steve Shifflett (1-2) S: Jeff Reardon (19) | Fourth | 11 out |
| » Major-league debuts: Paul Quantrill (Red Sox) |
| Tuesday, July 21 |
| » Lost to Royals (41-52), 8-0 | Royals Stadium (3-2) | 44-47 | |
| » W: Hipolito Pichardo (5-4) L: Joe Hesketh (4-7) | Fourth | 12 out |
| Wednesday, July 22 |
| » Lost to Royals (42-52), 6-4 | Royals Stadium (3-3) | 44-48 | Lost 2 |
| » W: Tom Gordon (3-9) L: Frank Viola (8-6) S: Jeff Montgomery (23) | Sixth | 12 out |
| Friday, July 24 |
| » Lost to Twins (58-37), 5-0 | Fenway Park (29-17) | 44-49 | Lost 3 |
| » W: Scott Erickson (7-7) L: Roger Clemens (10-7) | Sixth | 12 out |
| » Defeated Twins (58-38), 5-4 | Fenway Park (30-17) | 45-49 | |
| » W: Daryl Irvine (2-0) L: Carl Willis (4-3) | Sixth | 12 out |
| Saturday, July 25 |
| » Lost to Twins (59-38), 3-2 | Fenway Park (30-18) | 45-50 | |
| » W: Willie Banks (4-3) L: Danny Darwin (5-5) S: Rick Aguilera (29) | Sixth | 12 out |
| Sunday, July 26 |
| » Lost to Twins (60-38), 8-2 | Fenway Park (30-19) | 45-51 | Lost 2 |
| » W: Kevin Tapani (11-6) L: Joe Hesketh (4-8) S: Mark Guthrie (3) | Sixth | 12 out |
| Monday, July 27 |
| » Defeated Rangers (53-49), 7-5 | Fenway Park (31-19) | 46-51 | |
| » W: Frank Viola (9-6) L: Kevin Brown (14-7) S: Jeff Reardon (20) | Fourth | 11½ out |
| » Major-league debuts: John Valentin (Red Sox) |
| Tuesday, July 28 |
| » Lost to Rangers (54-49), 2-1 | Fenway Park (31-20) | 46-52 | |
| » W: Danilo Leon (1-1) L: Paul Quantrill (1-1) S: Jeff Russell (26) | Fifth | 12½ out |
| Wednesday, July 29 |
| » Defeated Rangers (54-50), 6-5 | Fenway Park (32-20) | 47-52 | |
| » W: Roger Clemens (11-7) L: Todd Burns (2-4) S: Jeff Reardon (21) | Fourth | 11½ out |
| Friday, July 31 |
| » Defeated Orioles (56-46), 7-4 | Fenway Park (33-20) | 48-52 | Won 2 |
| » W: Joe Hesketh (5-8) L: Todd Frohwirth (3-2) S: Jeff Reardon (22) | Fourth | 12½ out |
| » Lost to Orioles (57-46), 4-3 | Fenway Park (33-21) | 48-53 | |
| » W: Richie Lewis (1-0) L: Matt Young (0-3) S: Storm Davis (3) | Fourth | 12½ out |
| » Major-league debuts: Richie Lewis (Orioles) |
| Saturday, August 1 |
| » Lost to Orioles (58-46), 9-3 | Fenway Park (33-22) | 48-54 | Lost 2 |
| » W: Pat Clements (4-1) L: Frank Viola (9-7) | Fourth | 13½ out |
| Sunday, August 2 |
| » Lost to Orioles (59-46), 2-1 | Fenway Park (33-23) | 48-55 | Lost 3 |
| » W: Ben McDonald (11-7) L: Tony Fossas (1-2) S: Gregg Olson (25) | Fourth | 14½ out |
| Monday, August 3 |
| » Defeated Blue Jays (63-42), 7-1 | Fenway Park (34-23) | 49-55 | |
| » W: Roger Clemens (12-7) L: Juan Guzman (12-3) | Fourth | 13½ out |
| » Major-league debuts: Doug Linton (Blue Jays) |
| Tuesday, August 4 |
| » Defeated Blue Jays (63-43), 9-4 | Fenway Park (35-23) | 50-55 | Won 2 |
| » W: Joe Hesketh (6-8) L: David Wells (6-5) S: Greg Harris (2) | Fourth | 12½ out |
| Wednesday, August 5 |
| » Lost to Blue Jays (64-43), 5-4 | Fenway Park (35-24) | 50-56 | |
| » W: Mark Eichhorn (4-4) L: Daryl Irvine (2-1) S: Tom Henke (20) | Fourth | 13½ out |
| Thursday, August 6 |
| » Defeated Yankees (49-59), 3-1 | Yankee Stadium (1-2) | 51-56 | |
| » W: Frank Viola (10-7) L: Melido Perez (9-11) S: Jeff Reardon (23) | Fourth | 13½ out |
| Friday, August 7 |
| » Lost to Yankees (50-59), 7-5 | Yankee Stadium (1-3) | 51-57 | |
| » W: Scott Sanderson (9-8) L: John Dopson (6-5) S: Steve Farr (15) | Fourth | 13½ out |
| Saturday, August 8 |
| » Defeated Yankees (50-60), 4-2 | Yankee Stadium (2-3) | 52-57 | |
| » W: Roger Clemens (13-7) L: Scott Kamieniecki (2-9) S: Jeff Reardon (24) | Fourth | 12½ out |
| Sunday, August 9 |
| » Lost to Yankees (51-60), 6-0 | Yankee Stadium (2-4) | 52-58 | |
| » W: Sam Militello (1-0) L: Joe Hesketh (6-9) S: Steve Farr (16) | Fourth | 12½ out |
| » Major-league debuts: Sam Militello (Yankees) |
| Monday, August 10 |
| » Lost to Indians (50-62), 8-5 | Cleveland Stadium (2-2) | 52-59 | Lost 2 |
| » W: Jack Armstrong (4-13) L: Paul Quantrill (1-2) S: Steve Olin (19) | Fourth | 13½ out |
| Tuesday, August 11 |
| » Lost to Indians (51-62), 3-1 | Cleveland Stadium (2-3) | 52-60 | Lost 3 |
| » W: Dave Otto (5-8) L: Frank Viola (10-8) S: Derek Lilliquist (5) | Fifth | 13½ out |
| Wednesday, August 12 |
| » Lost to Indians (52-62), 8-5 | Cleveland Stadium (2-4) | 52-61 | Lost 4 |
| » W: Eric Plunk (3-2) L: Daryl Irvine (2-2) S: Steve Olin (20) | Fifth | 13½ out |
| Thursday, August 13 |
| » Defeated Indians (52-63), 4-2 | Cleveland Stadium (3-4) | 53-61 | |
| » W: Roger Clemens (14-7) L: Charles Nagy (12-8) S: Jeff Reardon (25) | Fifth | 13½ out |
| Friday, August 14 |
| » Lost to Brewers (61-53), 8-7 | County Stadium (1-2) | 53-62 | |
| » W: Jim Austin (3-2) L: Jeff Reardon (2-1) | Fifth | 15 out |
| » Lost to Brewers (62-53), 1-0 | County Stadium (1-3) | 53-63 | Lost 2 |
| » W: Cal Eldred (3-1) L: Greg Harris (2-7) S: Darren Holmes (2) | Fifth | 15 out |
| Saturday, August 15 |
| » Defeated Brewers (62-54), 3-1 | County Stadium (2-3) | 54-63 | |
| » W: Danny Darwin (6-5) L: Bill Wegman (10-10) | Fifth | 14½ out |
| Sunday, August 16 |
| » Lost to Brewers (63-54), 1-0 | County Stadium (2-4) | 54-64 | |
| » W: Jaime Navarro (13-8) L: Frank Viola (10-9) | Fifth | 15 out |
| Tuesday, August 18 |
| » Defeated Angels (53-67), 8-0 | Fenway Park (36-24) | 55-64 | |
| » W: Roger Clemens (15-7) L: Mark Langston (11-11) | Fifth | 15 out |
| Wednesday, August 19 |
| » Lost to Angels (54-67), 3-2 | Fenway Park (36-25) | 55-65 | |
| » W: Jim Abbott (5-12) L: Jeff Reardon (2-2) S: Joe Grahe (15) | Fifth | 15 out |
| Thursday, August 20 |
| » Lost to Angels (55-67), 2-0 | Fenway Park (36-26) | 55-66 | Lost 2 |
| » W: Bert Blyleven (7-5) L: Danny Darwin (6-6) S: Joe Grahe (16) | Sixth | 15 out |
| Friday, August 21 |
| » Lost to Mariners (50-73), 5-2 | Fenway Park (36-27) | 55-67 | Lost 3 |
| » W: Randy Johnson (10-12) L: Frank Viola (10-10) | Sixth | 15 out |
| Saturday, August 22 |
| » Defeated Mariners (50-74), 10-8 | Fenway Park (37-27) | 56-67 | |
| » W: Greg Harris (3-7) L: Shawn Barton (0-1) S: Jeff Reardon (26) | Sixth | 15 out |
| Sunday, August 23 |
| » Lost to Mariners (51-74), 9-3 | Fenway Park (37-28) | 56-68 | |
| » W: Dennis Powell (3-2) L: Roger Clemens (15-8) | Sixth | 15 out |
| Monday, August 24 |
| » Lost to Athletics (76-49), 9-3 | Fenway Park (37-29) | 56-69 | Lost 2 |
| » W: Dave Stewart (9-8) L: John Dopson (6-6) | Seventh | 15 out |
| » Major-league debuts: Todd Revenig (Athletics) |
| Tuesday, August 25 |
| » Defeated Athletics (76-50), 5-4 | Fenway Park (38-29) | 57-69 | |
| » W: Paul Quantrill (2-2) L: Dennis Eckersley (6-1) S: Jeff Reardon (27) | Seventh | 14 out |
| Wednesday, August 26 |
| » Defeated Athletics (76-51), 2-1 | Fenway Park (39-29) | 58-69 | Won 2 |
| » W: Frank Viola (11-10) L: Kevin Campbell (2-2) | Seventh | 14 out |
| Friday, August 28 |
| » Defeated Angels (58-71), 7-1 | Anaheim Stadium (4-0) | 59-69 | Won 3 |
| » W: Roger Clemens (16-8) L: Chuck Finley (4-11) | Sixth | 13½ out |
| Saturday, August 29 |
| » Lost to Angels (59-71), 7-2 | Anaheim Stadium (4-1) | 59-70 | |
| » W: Mark Langston (12-11) L: John Dopson (6-7) | Sixth | 13½ out |
| Sunday, August 30 |
| » Defeated Angels (59-72), 4-2 | Anaheim Stadium (5-1) | 60-70 | |
| » W: Danny Darwin (7-6) L: Mike Butcher (2-2) S: Greg Harris (3) | Sixth | 13½ out |
| Monday, August 31 |
| » Lost to Mariners (55-77), 15-2 | Kingdome (1-3) | 60-71 | |
| » W: Randy Johnson (11-12) L: Frank Viola (11-11) | Sixth | 14½ out |
| » Major-league debuts: Ken Ryan (Red Sox) |
| Tuesday, September 1 |
| » Lost to Mariners (56-77), 4-3 | Kingdome (1-4) | 60-72 | Lost 2 |
| » W: Mike Schooler (2-6) L: Greg Harris (3-8) | Sixth | 15½ out |
| Wednesday, September 2 |
| » Defeated Mariners (56-78), 5-3 | Kingdome (2-4) | 61-72 | |
| » W: Roger Clemens (17-8) L: Tim Leary (6-7) | Sixth | 14½ out |
| Friday, September 4 |
| » Defeated Athletics (79-55), 8-3 | Oakland-Alameda County Stadium (1-3) | 62-72 | Won 2 |
| » W: Danny Darwin (8-6) L: Dave Stewart (10-9) | Fifth | 14½ out |
| Saturday, September 5 |
| » Defeated Athletics (79-56), 7-3 | Oakland-Alameda County Stadium (2-3) | 63-72 | Won 3 |
| » W: John Dopson (7-7) L: Ron Darling (12-9) | Fourth | 14½ out |
| Sunday, September 6 |
| » Lost to Athletics (80-56), 2-1 | Oakland-Alameda County Stadium (2-4) | 63-73 | |
| » W: Dennis Eckersley (7-1) L: Paul Quantrill (2-3) | Fifth | 15½ out |
| Monday, September 7 |
| » Defeated Rangers (67-73), 3-0 | Arlington Stadium (1-3) | 64-73 | |
| » W: Roger Clemens (18-8) L: Nolan Ryan (5-9) S: Joe Hesketh (1) | Fifth | 14½ out |
| Tuesday, September 8 |
| » Lost to Rangers (68-73), 6-1 | Arlington Stadium (1-4) | 64-74 | |
| » W: Kevin Brown (19-8) L: Matt Young (0-4) | Fifth | 15½ out |
| Wednesday, September 9 |
| » Lost to Rangers (69-73), 3-2 | Arlington Stadium (1-5) | 64-75 | Lost 2 |
| » W: Jose Guzman (13-11) L: Danny Darwin (8-7) | Fifth | 16½ out |
| Friday, September 11 |
| » Defeated Tigers (65-77), 7-6 | Fenway Park (40-29) | 65-75 | |
| » W: Mike Gardiner (4-10) L: John Doherty (5-4) S: Ken Ryan (1) | Fifth | 16 out |
| Saturday, September 12 |
| » Lost to Tigers (66-77), 9-5 | Fenway Park (40-30) | 65-76 | |
| » W: Walt Terrell (6-10) L: Roger Clemens (18-9) | Seventh | 17 out |
| Sunday, September 13 |
| » Lost to Tigers (67-77), 7-2 | Fenway Park (40-31) | 65-77 | Lost 2 |
| » W: Frank Tanana (12-9) L: John Dopson (7-8) | Seventh | 18 out |
| Monday, September 14 |
| » Lost to Brewers (78-65), 6-0 | Fenway Park (40-32) | 65-78 | Lost 3 |
| » W: Chris Bosio (14-5) L: Danny Darwin (8-8) | Seventh | 18 out |
| Tuesday, September 15 |
| » Lost to Brewers (79-65), 7-2 | Fenway Park (40-33) | 65-79 | Lost 4 |
| » W: Jim Austin (4-2) L: Frank Viola (11-12) | Seventh | 19 out |
| Wednesday, September 16 |
| » Defeated Brewers (79-66), 2-1 | Fenway Park (41-33) | 66-79 | |
| » W: Daryl Irvine (3-2) L: Doug Henry (1-4) | Seventh | 18 out |
| Thursday, September 17 |
| » Lost to Brewers (80-66), 10-4 | Fenway Park (41-34) | 66-80 | |
| » W: Jaime Navarro (16-11) L: Roger Clemens (18-10) | Sixth | |