| Monday, April 6 |
| » Defeated Expos (0-1), 2-0 | Three Rivers Stadium (1-0) | 1-0 | |
| » W: Doug Drabek (1-0) L: Dennis Martinez (0-1) S: Roger Mason (1) | First | -- |
| Wednesday, April 8 |
| » Defeated Expos (0-2), 4-2 | Three Rivers Stadium (2-0) | 2-0 | Won 2 |
| » W: Zane Smith (1-0) L: Mark Gardner (0-1) S: Stan Belinda (1) | First | -- |
| » Major-league debuts: Archi Cianfrocco (Expos) |
| Thursday, April 9 |
| » Lost to Expos (1-2), 8-3 | Three Rivers Stadium (2-1) | 2-1 | |
| » W: Chris Nabholz (1-0) L: Bob Walk (0-1) | First | -- |
| Friday, April 10 |
| » Defeated Phillies (2-2), 3-2 | Veteran's Stadium (1-0) | 3-1 | |
| » W: Randy Tomlin (1-0) L: Kyle Abbott (0-1) S: Stan Belinda (2) | First | -- |
| Saturday, April 11 |
| » Lost to Phillies (3-2), 7-4 | Veteran's Stadium (1-1) | 3-2 | |
| » W: Andy Ashby (1-0) L: Doug Drabek (1-1) | First | -- |
| » Major-league debuts: Miguel Batista (Pirates) |
| Sunday, April 12 |
| » Defeated Phillies (3-3), 6-1 | Veteran's Stadium (2-1) | 4-2 | |
| » W: Zane Smith (2-0) L: Terry Mulholland (0-2) | First | -- |
| » Major-league debuts: Jeff Grotewold (Phillies) |
| Tuesday, April 14 |
| » Defeated Cubs (3-4), 3-2 | Three Rivers Stadium (3-1) | 5-2 | Won 2 |
| » W: Bob Walk (1-1) L: Danny Jackson (0-2) S: Roger Mason (2) | First | -- |
| Wednesday, April 15 |
| » Defeated Cubs (3-5), 7-2 | Three Rivers Stadium (4-1) | 6-2 | Won 3 |
| » W: Randy Tomlin (2-0) L: Mike Morgan (0-2) | First | -- |
| Friday, April 17 |
| » Defeated Phillies (4-6), 7-4 | Three Rivers Stadium (5-1) | 7-2 | Won 4 |
| » W: Doug Drabek (2-1) L: Barry Jones (0-1) S: Stan Belinda (3) | First | -- |
| Saturday, April 18 |
| » Defeated Phillies (4-7), 9-2 | Three Rivers Stadium (6-1) | 8-2 | Won 5 |
| » W: Zane Smith (3-0) L: Tommy Greene (1-1) | First | -- |
| Sunday, April 19 |
| » Defeated Phillies (4-8), 11-0 | Three Rivers Stadium (7-1) | 9-2 | Won 6 |
| » W: Bob Patterson (1-0) L: Danny Cox (1-1) | First | -- |
| Monday, April 20 |
| » Defeated Expos (6-7), 11-1 | Stade Olympique (1-0) | 10-2 | Won 7 |
| » W: Randy Tomlin (3-0) L: Ken Hill (1-2) | First | -- |
| Tuesday, April 21 |
| » Defeated Expos (6-8), 8-7 | Stade Olympique (2-0) | 11-2 | Won 8 |
| » W: Vicente Palacios (1-0) L: Chris Haney (1-1) S: Roger Mason (3) | First | -- |
| Wednesday, April 22 |
| » Defeated Expos (6-9), 2-0 | Stade Olympique (3-0) | 12-2 | Won 9 |
| » W: Doug Drabek (3-1) L: Dennis Martinez (1-3) | First | -- |
| Thursday, April 23 |
| » Lost to Expos (7-9), 6-3 | Stade Olympique (3-1) | 12-3 | |
| » W: Mark Gardner (2-1) L: Zane Smith (3-1) S: John Wetteland (3) | First | -- |
| Friday, April 24 |
| » Defeated Cubs (6-9), 3-2 | Wrigley Field (1-0) | 13-3 | |
| » W: Roger Mason (1-0) L: Bob Scanlan (0-1) S: Stan Belinda (4) | First | -- |
| Saturday, April 25 |
| » Defeated Cubs (6-10), 1-0 | Wrigley Field (2-0) | 14-3 | Won 2 |
| » W: Randy Tomlin (4-0) L: Greg Maddux (3-1) S: Stan Belinda (5) | First | -- |
| Sunday, April 26 |
| » Lost to Cubs (7-10), 5-4 | Wrigley Field (2-1) | 14-4 | |
| » W: Chuck McElroy (1-0) L: Roger Mason (1-1) | First | -- |
| Tuesday, April 28 |
| » Lost to Reds (11-9), 3-2 | Riverfront Stadium (0-1) | 14-5 | Lost 2 |
| » W: Tom Browning (3-1) L: Doug Drabek (3-2) S: Norm Charlton (7) | First | -- |
| Wednesday, April 29 |
| » Defeated Reds (11-10), 4-0 | Riverfront Stadium (1-1) | 15-5 | |
| » W: Zane Smith (4-1) L: Tim Belcher (1-3) | First | -- |
| Friday, May 1 |
| » Lost to Astros (11-11), 10-4 | Astrodome (0-1) | 15-6 | |
| » W: Pete Harnisch (2-3) L: Randy Tomlin (4-1) | First | -- |
| Saturday, May 2 |
| » Defeated Astros (11-12), 6-0 | Astrodome (1-1) | 16-6 | |
| » W: Denny Neagle (1-0) L: Ryan Bowen (0-3) | First | -- |
| Sunday, May 3 |
| » Lost to Astros (12-12), 1-0 | Astrodome (1-2) | 16-7 | |
| » W: Al Osuna (3-0) L: Roger Mason (1-2) S: Doug Jones (7) | First | -- |
| Monday, May 4 |
| » Defeated Reds (13-12), 12-5 | Three Rivers Stadium (8-1) | 17-7 | |
| » W: Dennis Lamp (1-0) L: Dwayne Henry (0-1) | First | -- |
| Tuesday, May 5 |
| » Defeated Reds (13-13), 5-2 | Three Rivers Stadium (9-1) | 18-7 | Won 2 |
| » W: Paul Miller (1-0) L: Tim Belcher (1-4) S: Stan Belinda (6) | First | -- |
| Wednesday, May 6 |
| » Defeated Braves (13-15), 4-3 | Three Rivers Stadium (10-1) | 19-7 | Won 3 |
| » W: Bob Patterson (2-0) L: Ben Rivera (0-1) | First | -- |
| Thursday, May 7 |
| » Lost to Braves (14-15), 4-2 | Three Rivers Stadium (10-2) | 19-8 | |
| » W: Tom Glavine (5-1) L: Denny Neagle (1-1) S: Mike Stanton (2) | First | -- |
| Friday, May 8 |
| » Defeated Astros (13-16), 6-3 | Three Rivers Stadium (11-2) | 20-8 | |
| » W: Stan Belinda (1-0) L: Al Osuna (3-1) | First | -- |
| Saturday, May 9 |
| » Defeated Astros (13-17), 3-0 | Three Rivers Stadium (12-2) | 21-8 | Won 2 |
| » W: Zane Smith (5-1) L: Darryl Kile (2-4) | First | -- |
| Sunday, May 10 |
| » Lost to Astros (14-17), 6-4 | Three Rivers Stadium (12-3) | 21-9 | |
| » W: Doug Jones (2-1) L: Roger Mason (1-3) | First | -- |
| Tuesday, May 12 |
| » Lost to Braves (16-18), 4-2 | Atlanta-Fulton County Stadium (0-1) | 21-10 | Lost 2 |
| » W: Tom Glavine (6-1) L: Randy Tomlin (4-2) S: Marvin Freeman (2) | First | -- |
| Wednesday, May 13 |
| » Defeated Braves (16-19), 11-10 | Atlanta-Fulton County Stadium (1-1) | 22-10 | |
| » W: Stan Belinda (2-0) L: Alejandro Pena (0-4) | First | -- |
| Thursday, May 14 |
| » Defeated Braves (16-20), 4-3 | Atlanta-Fulton County Stadium (2-1) | 23-10 | Won 2 |
| » W: Vicente Palacios (2-0) L: John Smoltz (3-3) S: Roger Mason (4) | First | -- |
| Friday, May 15 |
| » Lost to Padres (18-17), 9-2 | Three Rivers Stadium (12-4) | 23-11 | |
| » W: Craig Lefferts (4-2) L: Denny Neagle (1-2) | First | -- |
| Saturday, May 16 |
| » Lost to Padres (19-17), 10-9 | Three Rivers Stadium (12-5) | 23-12 | Lost 2 |
| » W: Rich Rodriguez (3-1) L: Bob Walk (1-2) S: Randy Myers (10) | First | -- |
| Sunday, May 17 |
| » Lost to Padres (20-17), 6-5 | Three Rivers Stadium (12-6) | 23-13 | Lost 3 |
| » W: Andy Benes (4-3) L: Randy Tomlin (4-3) S: Randy Myers (11) | First | -- |
| Tuesday, May 19 |
| » Lost to Giants (21-16), 7-2 | Candlestick Park (0-1) | 23-14 | Lost 4 |
| » W: Trevor Wilson (4-2) L: Doug Drabek (3-3) S: Dave Righetti (2) | First | -- |
| Wednesday, May 20 |
| » Lost to Giants (22-16), 3-1 | Candlestick Park (0-2) | 23-15 | Lost 5 |
| » W: Bud Black (1-1) L: Zane Smith (5-2) S: Jeff Brantley (4) | First | -- |
| Thursday, May 21 |
| » Lost to Giants (23-16), 1-0 | Candlestick Park (0-3) | 23-16 | Lost 6 |
| » W: John Burkett (4-1) L: Bob Walk (1-3) S: Mike Jackson (2) | First | -- |
| Friday, May 22 |
| » Defeated Dodgers (15-22), 6-4 | Dodger Stadium (1-0) | 24-16 | |
| » W: Randy Tomlin (5-3) L: Tom Candiotti (4-3) | First | -- |
| Saturday, May 23 |
| » Lost to Dodgers (16-22), 5-4 | Dodger Stadium (1-1) | 24-17 | |
| » W: Steve Wilson (1-3) L: Stan Belinda (2-1) | First | -- |
| Sunday, May 24 |
| » Lost to Dodgers (17-22), 4-2 | Dodger Stadium (1-2) | 24-18 | Lost 2 |
| » W: Kevin Gross (2-4) L: Doug Drabek (3-4) S: Roger McDowell (6) | Second | ½ out |
| Monday, May 25 |
| » Lost to Padres (24-21), 7-6 | San Diego/Jack Murphy Stadium (0-1) | 24-19 | Lost 3 |
| » W: Craig Lefferts (6-2) L: Zane Smith (5-3) S: Randy Myers (12) | Second | 1½ out |
| Tuesday, May 26 |
| » Lost to Padres (25-21), 6-3 | San Diego/Jack Murphy Stadium (0-2) | 24-20 | Lost 4 |
| » W: Tim Scott (1-0) L: Dennis Lamp (1-1) | Second | 1½ out |
| Wednesday, May 27 |
| » Lost to Padres (26-21), 8-7 | San Diego/Jack Murphy Stadium (0-3) | 24-21 | Lost 5 |
| » W: Randy Myers (2-1) L: Stan Belinda (2-2) | Second | 1½ out |
| Friday, May 29 |
| » Defeated Giants (26-20), 13-3 | Three Rivers Stadium (13-6) | 25-21 | |
| » W: Vicente Palacios (3-0) L: Trevor Wilson (4-4) S: Bob Patterson (1) | Second | ½ out |
| Saturday, May 30 |
| » Defeated Giants (26-21), 3-2 | Three Rivers Stadium (14-6) | 26-21 | Won 2 |
| » W: Denny Neagle (2-2) L: Jeff Brantley (2-2) | Second | ½ out |
| Sunday, May 31 |
| » Lost to Giants (27-21), 5-3 | Three Rivers Stadium (14-7) | 26-22 | |
| » W: Bud Black (2-1) L: Zane Smith (5-4) S: Jeff Brantley (6) | Second | ½ out |
| Monday, June 1 |
| » Lost to Dodgers (23-23), 8-6 | Three Rivers Stadium (14-8) | 26-23 | Lost 2 |
| » W: Jim Gott (1-1) L: Denny Neagle (2-3) S: John Candelaria (3) | Second | 1 out |
| Tuesday, June 2 |
| » Defeated Dodgers (23-24), 1-0 | Three Rivers Stadium (15-8) | 27-23 | |
| » W: Randy Tomlin (6-3) L: Tom Candiotti (5-4) S: Roger Mason (5) | First | -- |
| Wednesday, June 3 |
| » Defeated Dodgers (23-25), 6-5 | Three Rivers Stadium (16-8) | 28-23 | Won 2 |
| » W: Jerry Don Gleaton (1-0) L: Ramon Martinez (3-2) S: Stan Belinda (7) | First | -- |
| Thursday, June 4 |
| » Defeated Mets (27-25), 7-2 | Three Rivers Stadium (17-8) | 29-23 | Won 3 |
| » W: Doug Drabek (4-4) L: Dwight Gooden (4-6) S: Bob Patterson (2) | First | -- |
| Friday, June 5 |
| » Defeated Mets (27-26), 5-4 | Three Rivers Stadium (18-8) | 30-23 | Won 4 |
| » W: Stan Belinda (3-2) L: Jeff Innis (4-2) | First | -- |
| Saturday, June 6 |
| » Lost to Mets (28-26), 15-1 | Three Rivers Stadium (18-9) | 30-24 | |
| » W: Sid Fernandez (5-5) L: Denny Neagle (2-4) | First | -- |
| » Major-league debuts: Victor Cole (Pirates) |
| Sunday, June 7 |
| » Defeated Mets (28-27), 3-0 | Three Rivers Stadium (19-9) | 31-24 | |
| » W: Randy Tomlin (7-3) L: Pete Schourek (0-2) | First | -- |
| Monday, June 8 |
| » Lost to Phillies (26-28), 7-0 | Veteran's Stadium (2-2) | 31-25 | |
| » W: Curt Schilling (5-3) L: Vicente Palacios (3-1) | First | -- |
| Tuesday, June 9 |
| » Defeated Phillies (26-29), 5-3 | Veteran's Stadium (3-2) | 32-25 | |
| » W: Doug Drabek (5-4) L: Mike Hartley (2-1) S: Denny Neagle (1) | First | -- |
| Wednesday, June 10 |
| » Defeated Phillies (26-30), 2-1 | Veteran's Stadium (4-2) | 33-25 | Won 2 |
| » W: Bob Patterson (3-0) L: Barry Jones (4-3) S: Roger Mason (6) | First | -- |
| Friday, June 12 |
| » Defeated Mets (29-30), 3-2 | Shea Stadium (1-0) | 34-25 | Won 3 |
| » W: Randy Tomlin (8-3) L: Sid Fernandez (5-6) S: Bob Patterson (3) | First | -- |
| Saturday, June 13 |
| » Defeated Mets (29-31), 3-2 | Shea Stadium (2-0) | 35-25 | Won 4 |
| » W: Jeff Robinson (5-4) L: Wally Whitehurst (1-3) S: Stan Belinda (8) | First | -- |
| Sunday, June 14 |
| » Defeated Mets (29-32), 5-4 | Shea Stadium (3-0) | 36-25 | Won 5 |
| » W: Denny Neagle (3-4) L: Jeff Innis (4-3) S: Stan Belinda (9) | First | -- |
| Monday, June 15 |
| » Lost to Phillies (28-32), 4-1 | Three Rivers Stadium (19-10) | 36-26 | |
| » W: Terry Mulholland (6-4) L: Zane Smith (5-5) | First | -- |
| Tuesday, June 16 |
| » Defeated Phillies (28-33), 6-5 | Three Rivers Stadium (20-10) | 37-26 | |
| » W: Bob Patterson (4-0) L: Cliff Brantley (2-5) | First | -- |
| Wednesday, June 17 |
| » Defeated Phillies (28-34), 8-2 | Three Rivers Stadium (21-10) | 38-26 | Won 2 |
| » W: Randy Tomlin (9-3) L: Don Robinson (2-1) | First | -- |
| Thursday, June 18 |
| » Lost to Expos (29-33), 4-0 | Three Rivers Stadium (21-11) | 38-27 | |
| » W: Chris Nabholz (5-5) L: Vicente Palacios (3-2) S: Jeff Fassero (1) | First | -- |
| Friday, June 19 |
| » Lost to Expos (30-33), 2-1 | Three Rivers Stadium (21-12) | 38-28 | Lost 2 |
| » W: Ken Hill (6-4) L: Doug Drabek (5-5) S: John Wetteland (11) | First | -- |
| Saturday, June 20 |
| » Lost to Expos (31-33), 4-3 | Three Rivers Stadium (21-13) | 38-29 | Lost 3 |
| » W: Mark Gardner (6-5) L: Zane Smith (5-6) S: John Wetteland (12) | First | -- |
| Sunday, June 21 |
| » Defeated Expos (31-34), 5-4 | Three Rivers Stadium (22-13) | 39-29 | |
| » W: Jeff Robinson (6-4) L: Dennis Martinez (7-6) S: Stan Belinda (10) | First | -- |
| Monday, June 22 |
| » Defeated Cardinals (33-35), 5-2 | Three Rivers Stadium (23-13) | 40-29 | Won 2 |
| » W: Randy Tomlin (10-3) L: Donovan Osborne (5-4) S: Bob Walk (1) | First | -- |
| Tuesday, June 23 |
| » Defeated Cardinals (33-36), 6-4 | Three Rivers Stadium (24-13) | 41-29 | Won 3 |
| » W: Roger Mason (2-3) L: Todd Worrell (3-3) S: Bob Patterson (4) | First | -- |
| Wednesday, June 24 |
| » Lost to Cardinals (34-36), 4-1 | Three Rivers Stadium (24-14) | 41-30 | |
| » W: Bob Tewksbury (8-2) L: Doug Drabek (5-6) | First | -- |
| Friday, June 26 |
| » Lost to Expos (33-36), 6-2 | Stade Olympique (3-2) | 41-31 | Lost 2 |
| » W: Dennis Martinez (8-6) L: Zane Smith (5-7) S: Mel Rojas (3) | First | -- |
| Saturday, June 27 |
| » Defeated Expos (33-37), 12-4 | Stade Olympique (4-2) | 42-31 | |
| » W: Jeff Robinson (7-4) L: Mark Gardner (6-6) S: Stan Belinda (11) | First | -- |
| » Major-league debuts: Will Pennyfeather (Pirates) |
| Former Pirate Woody Main dies in Whittier, CA at the age of 71. |
| Sunday, June 28 |
| » Lost to Expos (34-37), 9-0 | Stade Olympique (4-3) | 42-32 | |
| » W: Brian Barnes (1-1) L: Randy Tomlin (10-4) | First | -- |
| Monday, June 29 |
| » Lost to Cardinals (37-37), 3-1 | Busch Stadium II (0-1) | 42-33 | Lost 2 |
| » W: Bob Tewksbury (9-2) L: Victor Cole (0-1) | First | -- |
| Tuesday, June 30 |
| » Defeated Cardinals (37-38), 2-0 | Busch Stadium II (1-1) | 43-33 | |
| » W: Doug Drabek (6-6) L: Rheal Cormier (1-6) | First | -- |
| Wednesday, July 1 |
| » Defeated Cardinals (37-39), 1-0 | Busch Stadium II (2-1) | 44-33 | Won 2 |
| » W: Zane Smith (6-7) L: Mark Clark (0-3) | First | -- |
| Thursday, July 2 |
| » Lost to Reds (45-31), 2-1 | Three Rivers Stadium (24-15) | 44-34 | |
| » W: Jose Rijo (5-6) L: Jeff Robinson (7-5) S: Norm Charlton (18) | First | -- |
| Friday, July 3 |
| » Lost to Reds (46-31), 7-3 | Three Rivers Stadium (24-16) | 44-35 | Lost 2 |
| » W: Tim Belcher (8-6) L: Randy Tomlin (10-5) | First | -- |
| Saturday, July 4 |
| » Lost to Reds (47-31), 5-2 | Three Rivers Stadium (24-17) | 44-36 | Lost 3 |
| » W: Greg Swindell (8-2) L: Victor Cole (0-2) | First | -- |
| Sunday, July 5 |
| » Lost to Reds (48-31), 2-1 | Three Rivers Stadium (24-18) | 44-37 | Lost 4 |
| » W: Tony Menendez (1-0) L: Doug Drabek (6-7) S: Norm Charlton (19) | First | -- |
| Monday, July 6 |
| » Defeated Astros (38-44), 1-0 | Three Rivers Stadium (25-18) | 45-37 | |
| » W: Zane Smith (7-7) L: Jimmy Jones (4-2) S: Stan Belinda (12) | First | -- |
| Tuesday, July 7 |
| » Defeated Astros (38-45), 5-3 | Three Rivers Stadium (26-18) | 46-37 | Won 2 |
| » W: Bob Walk (2-3) L: Joe Boever (2-4) | First | -- |
| Wednesday, July 8 |
| » Lost to Astros (39-45), 3-2 | Three Rivers Stadium (26-19) | 46-38 | |
| » W: Doug Jones (6-5) L: Bob Patterson (4-1) | First | -- |
| Thursday, July 9 |
| » Lost to Reds (51-32), 5-2 | Riverfront Stadium (1-2) | 46-39 | Lost 2 |
| » W: Scott Bankhead (9-2) L: Roger Mason (2-4) S: Norm Charlton (21) | First | -- |
| Friday, July 10 |
| » Defeated Reds (51-33), 4-0 | Riverfront Stadium (2-2) | 47-39 | |
| » W: Doug Drabek (7-7) L: Chris Hammond (5-5) | First | -- |
| Saturday, July 11 |
| » Defeated Reds (51-34), 9-3 | Riverfront Stadium (3-2) | 48-39 | Won 2 |
| » W: Zane Smith (8-7) L: Keith Brown (0-1) | First | -- |
| Sunday, July 12 |
| » Defeated Reds (51-35), 7-6 | Riverfront Stadium (4-2) | 49-39 | Won 3 |
| » W: Bob Patterson (5-1) L: Tim Belcher (8-7) S: Stan Belinda (13) | First | -- |
| Thursday, July 16 |
| » Defeated Cubs (40-48), 2-1 | Three Rivers Stadium (27-19) | 50-39 | Won 4 |
| » W: Doug Drabek (8-7) L: Shawn Boskie (5-6) S: Stan Belinda (14) | First | -- |
| Friday, July 17 |
| » Lost to Cubs (41-48), 2-1 | Three Rivers Stadium (27-20) | 50-40 | |
| » W: Greg Maddux (11-8) L: Randy Tomlin (10-6) S: Bob Scanlan (4) | First | -- |
| Saturday, July 18 |
| » Defeated Cubs (41-49), 4-0 | Three Rivers Stadium (28-20) | 51-40 | |
| » W: Bob Walk (3-3) L: Mike Morgan (7-4) S: Bob Patterson (5) | First | -- |
| Sunday, July 19 |
| » Lost to Cubs (42-49), 4-2 | Three Rivers Stadium (28-21) | 51-41 | |
| » W: Bob Scanlan (3-5) L: Denny Neagle (3-5) | First | -- |
| Monday, July 20 |
| » Lost to Astros (42-51), 11-8 | Astrodome (1-3) | 51-42 | Lost 2 |
| » W: Willie Blair (2-4) L: Roger Mason (2-5) S: Doug Jones (20) | First | -- |
| » Major-league debuts: Shane Reynolds (Astros) |
| Tuesday, July 21 |
| » Lost to Astros (43-51), 4-3 | Astrodome (1-4) | 51-43 | Lost 3 |
| » W: Doug Jones (7-6) L: Roger Mason (2-6) | First | -- |
| Wednesday, July 22 |
| » Defeated Astros (43-52), 10-7 | Astrodome (2-4) | 52-43 | |
| » W: Stan Belinda (4-2) L: Willie Blair (2-5) S: Bob Patterson (6) | First | -- |
| Friday, July 24 |
| » Lost to Braves (56-37), 4-3 | Atlanta-Fulton County Stadium (2-2) | 52-44 | |
| » W: Tom Glavine (15-3) L: Bob Walk (3-4) S: Alejandro Pena (11) | First | -- |
| Saturday, July 25 |
| » Lost to Braves (57-37), 1-0 | Atlanta-Fulton County Stadium (2-3) | 52-45 | Lost 2 |
| » W: Charlie Leibrandt (8-3) L: Danny Jackson (4-10) S: Kent Mercker (5) | First | -- |
| Sunday, July 26 |
| » Defeated Braves (57-38), 5-4 | Atlanta-Fulton County Stadium (3-3) | 53-45 | |
| » W: Stan Belinda (5-2) L: Mark Wohlers (0-2) | First | -- |
| » Major-league debuts: Paul Wagner (Pirates) |
| Monday, July 27 |
| » Lost to Cubs (47-51), 3-2 | Wrigley Field (2-2) | 53-46 | |
| » W: Greg Maddux (13-8) L: Doug Drabek (8-8) S: Jeff Robinson (1) | First | -- |
| Tuesday, July 28 |
| » Lost to Cubs (48-51), 11-1 | Wrigley Field (2-3) | 53-47 | Lost 2 |
| » W: Mike Morgan (9-4) L: Randy Tomlin (10-7) | First | -- |
| » Major-league debuts: Steve Cooke, Al Martin and Blas Minor (Pirates) |
| Wednesday, July 29 |
| » Lost to Cubs (49-51), 6-4 | Wrigley Field (2-4) | 53-48 | Lost 3 |
| » W: Paul Assenmacher (3-2) L: Stan Belinda (5-3) | First | -- |
| Thursday, July 30 |
| » Defeated Cardinals (48-53), 4-0 | Three Rivers Stadium (29-21) | 54-48 | |
| » W: Danny Jackson (5-10) L: Mark Clark (2-5) S: Bob Patterson (7) | First | -- |
| Friday, July 31 |
| » Defeated Cardinals (48-54), 3-2 | Three Rivers Stadium (30-21) | 55-48 | Won 2 |
| » W: Tim Wakefield (1-0) L: Jose DeLeon (2-7) | First | -- |
| » Major-league debuts: Tim Wakefield (Pirates) |
| Saturday, August 1 |
| » Defeated Cardinals (48-55), 4-1 | Three Rivers Stadium (31-21) | 56-48 | Won 3 |
| » W: Doug Drabek (9-8) L: Omar Olivares (6-7) | First | -- |
| Sunday, August 2 |
| » Defeated Cardinals (48-56), 2-1 | Three Rivers Stadium (32-21) | 57-48 | Won 4 |
| » W: Bob Walk (4-4) L: Lee Smith (3-4) | First | -- |
| Tuesday, August 4 |
| » Defeated Mets (51-54), 3-2 | Three Rivers Stadium (33-21) | 58-48 | Won 5 |
| » W: Bob Walk (5-4) L: Tom Filer (0-1) | First | -- |
| Wednesday, August 5 |
| » Defeated Mets (51-55), 6-2 | Three Rivers Stadium (34-21) | 59-48 | Won 6 |
| » W: Tim Wakefield (2-0) L: Pete Schourek (3-5) | First | -- |
| Thursday, August 6 |
| » Defeated Cardinals (51-57), 3-2 | Busch Stadium II (3-1) | 60-48 | Won 7 |
| » W: Roger Mason (3-6) L: Lee Smith (3-5) S: Denny Neagle (2) | First | -- |
| Friday, August 7 |
| » Defeated Cardinals (51-58), 5-1 | Busch Stadium II (4-1) | 61-48 | Won 8 |
| » W: Randy Tomlin (11-7) L: Rheal Cormier (3-9) | First | -- |
| Saturday, August 8 |
| » Defeated Cardinals (51-59), 2-1 | Busch Stadium II (5-1) | 62-48 | Won 9 |
| » W: Bob Walk (6-4) L: Bob Tewksbury (11-5) S: Stan Belinda (15) | First | -- |
| Sunday, August 9 |
| » Defeated Cardinals (51-60), 7-5 | Busch Stadium II (6-1) | 63-48 | Won 10 |
| » W: Roger Mason (4-6) L: Mark Clark (2-6) S: Bob Walk (2) | First | -- |
| Monday, August 10 |
| » Defeated Mets (51-60), 4-2 | Shea Stadium (4-0) | 64-48 | Won 11 |
| » W: Steve Cooke (1-0) L: Lee Guetterman (3-3) | First | -- |
| Tuesday, August 11 |
| » Lost to Mets (52-60), 2-0 | Shea Stadium (4-1) | 64-49 | |
| » W: Eric Hillman (1-0) L: Doug Drabek (9-9) S: John Franco (13) | First | -- |
| Wednesday, August 12 |
| » Defeated Mets (52-61), 7-6 | Shea Stadium (5-1) | 65-49 | |
| » W: Denny Neagle (4-5) L: John Franco (6-2) S: Bob Patterson (8) | First | -- |
| Friday, August 14 |
| » Lost to Braves (69-44), 15-0 | Three Rivers Stadium (34-22) | 65-50 | |
| » W: Tom Glavine (18-3) L: Zane Smith (8-8) | First | -- |
| Saturday, August 15 |
| » Lost to Braves (70-44), 7-5 | Three Rivers Stadium (34-23) | 65-51 | Lost 2 |
| » W: Steve Avery (10-8) L: Danny Jackson (5-11) S: Alejandro Pena (14) | First | -- |
| Sunday, August 16 |
| » Defeated Braves (70-45), 4-2 | Three Rivers Stadium (35-23) | 66-51 | |
| » W: Tim Wakefield (3-0) L: John Smoltz (14-8) | First | -- |
| Monday, August 17 |
| » Lost to Braves (71-45), 5-4 | Three Rivers Stadium (35-24) | 66-52 | |
| » W: Marvin Freeman (5-4) L: Bob Patterson (5-2) S: Alejandro Pena (15) | First | -- |
| Tuesday, August 18 |
| » Defeated Padres (64-55), 5-1 | Three Rivers Stadium (36-24) | 67-52 | |
| » W: Randy Tomlin (12-7) L: Andy Benes (9-11) | First | -- |
| Wednesday, August 19 |
| » Defeated Padres (64-56), 3-2 | Three Rivers Stadium (37-24) | 68-52 | Won 2 |
| » W: Bob Walk (7-4) L: Jim Deshaies (3-3) S: Danny Cox (1) | First | -- |
| Thursday, August 20 |
| » Defeated Padres (64-57), 7-1 | Three Rivers Stadium (38-24) | 69-52 | Won 3 |
| » W: Danny Jackson (6-11) L: Craig Lefferts (12-8) | First | -- |
| Friday, August 21 |
| » Lost to Giants (58-64), 6-5 | Candlestick Park (0-4) | 69-53 | |
| » W: John Burkett (11-6) L: Tim Wakefield (3-1) S: Rod Beck (13) | First | -- |
| Saturday, August 22 |
| » Defeated Giants (58-65), 9-2 | Candlestick Park (1-4) | 70-53 | |
| » W: Doug Drabek (10-9) L: Francisco Oliveras (0-3) | First | -- |
| Sunday, August 23 |
| » Lost to Giants (59-65), 5-2 | Candlestick Park (1-5) | 70-54 | |
| » W: Bud Black (10-6) L: Randy Tomlin (12-8) | First | -- |
| Monday, August 24 |
| » Lost to Dodgers (53-72), 5-4 | Dodger Stadium (1-3) | 70-55 | Lost 2 |
| » W: Jim Gott (2-2) L: Denny Neagle (4-6) S: John Candelaria (4) | First | -- |
| Tuesday, August 25 |
| » Defeated Dodgers (53-73), 10-3 | Dodger Stadium (2-3) | 71-55 | |
| » W: Danny Cox (3-2) L: Ramon Martinez (8-11) | First | -- |
| Wednesday, August 26 |
| » Defeated Dodgers (53-74), 2-0 | Dodger Stadium (3-3) | 72-55 | Won 2 |
| » W: Tim Wakefield (4-1) L: Tom Candiotti (9-11) | First | -- |
| Friday, August 28 |
| » Lost to Padres (69-58), 11-6 | San Diego/Jack Murphy Stadium (0-4) | 72-56 | |
| » W: Mike Maddux (2-1) L: Doug Drabek (10-10) | First | -- |
| Saturday, August 29 |
| » Defeated Padres (69-59), 3-2 | San Diego/Jack Murphy Stadium (1-4) | 73-56 | |
| » W: Randy Tomlin (13-8) L: Greg Harris (2-6) S: Roger Mason (7) | First | -- |
| Sunday, August 30 |
| » Defeated Padres (69-60), 6-3 | San Diego/Jack Murphy Stadium (2-4) | 74-56 | Won 2 |
| » W: Bob Walk (8-4) L: Jim Deshaies (3-4) | First | -- |
| Tuesday, September 1 |
| » Defeated Giants (59-72), 5-3 | Three Rivers Stadium (39-24) | 75-56 | Won 3 |
| » W: Danny Jackson (7-11) L: John Burkett (11-8) S: Roger Mason (8) | First | -- |
| Wednesday, September 2 |
| » Defeated Giants (59-73), 3-2 | Three Rivers Stadium (40-24) | 76-56 | Won 4 |
| » W: Tim Wakefield (5-1) L: Bud Black (10-7) S: Bob Patterson (9) | First | -- |
| Thursday, September 3 |
| » Defeated Giants (59-74), 9-3 | Three Rivers Stadium (41-24) | 77-56 | Won 5 |
| » W: Doug Drabek (11-10) L: Jeff Brantley (3-7) | First | -- |
| Friday, September 4 |
| » Defeated Dodgers (54-80), 6-5 | Three Rivers Stadium (42-24) | 78-56 | Won 6 |
| » W: Bob Patterson (6-2) L: Jim Gott (2-3) | First | -- |
| Saturday, September 5 |
| » Defeated Dodgers (54-81), 6-1 | Three Rivers Stadium (43-24) | 79-56 | Won 7 |
| » W: Bob Walk (9-4) L: Orel Hershiser (9-12) | First | -- |
| Former Pirate Ron Davis dies in Houston, TX at the age of 51. Former Pirate Billy Herman dies in W.Palm Beach, FL at the age of 84. |
| Sunday, September 6 |
| » Lost to Dodgers (55-81), 7-5 | Three Rivers Stadium (43-25) | 79-57 | |
| » W: Tom Candiotti (10-12) L: Danny Cox (3-3) S: Jay Howell (2) | First | -- |
| Monday, September 7 |
| » Lost to Cubs (69-67), 6-5 | Three Rivers Stadium (43-26) | 79-58 | Lost 2 |
| » W: Paul Assenmacher (4-2) L: Stan Belinda (5-4) S: Bob Scanlan (13) | First | -- |
| » Major-league debuts: Fernando Ramsey (Cubs) |
| Tuesday, September 8 |
| » Defeated Cubs (69-68), 5-2 | Three Rivers Stadium (44-26) | 80-58 | |
| » W: Doug Drabek (12-10) L: Shawn Boskie (5-8) | First | -- |
| Wednesday, September 9 |
| » Defeated Cubs (69-69), 13-8 | Three Rivers Stadium (45-26) | 81-58 | Won 2 |
| » W: Danny Cox (4-3) L: Jeff Robinson (3-3) | First | -- |
| Friday, September 11 |
| » Lost to Phillies (57-81), 5-2 | Veteran's Stadium (4-3) | 81-59 | |
| » W: Ben Rivera (5-3) L: Bob Walk (9-5) S: Mitch Williams (25) | First | -- |
| Saturday, September 12 |
| » Defeated Phillies (57-82), 9-7 | Veteran's Stadium (5-3) | 82-59 | |
| » W: Stan Belinda (6-4) L: Mitch Williams (3-8) | First | -- |
| Sunday, September 13 |
| » Lost to Phillies (58-82), 6-3 | Veteran's Stadium (5-4) | 82-60 | |
| » W: Terry Mulholland (13-10) L: Bob Patterson (6-3) | First | -- |
| Monday, September 14 |
| » Defeated Cardinals (71-70), 5-4 | Busch Stadium II (7-1) | 83-60 | |
| » W: Doug Drabek (13-10) L: Lee Smith (3-7) S: Stan Belinda (16) | First | -- |
| Tuesday, September 15 |
| » Defeated Cardinals (71-71), 4-2 | Busch Stadium II (8-1) | 84-60 | Won 2 |
| » W: Paul Wagner (1-0) L: Mark Clark (3-10) S: Danny Cox (2) | First | -- |
| Wednesday, September 16 |
| » Lost to Expos (81-64), 6-3 | Three Rivers Stadium (45-27) | 84-61 | |
| » W: Chris Nabholz (10-10) L: Bob Walk (9-6) S: John Wetteland (35) | First | -- |
| Thursday, September 17 |
| » Defeated Expos (81-65), 3-2 | Three Rivers Stadium (46-27) | 85-61 | |
| » W: Danny Cox (5-3) L: Kent Bottenfield (0-1) | First | -- |
| Friday, September 18 |
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