| Monday, April 6 |
| » Lost to Rangers (1-0), 12-10 | Kingdome (0-1) | 0-1 | |
| » W: Steve Fireovid (1-0) L: Mike Schooler (0-1) S: Jeff Russell (1) | Third | 1 out |
| Tuesday, April 7 |
| » Lost to Rangers (2-0), 4-0 | Kingdome (0-2) | 0-2 | Lost 2 |
| » W: Kevin Brown (1-0) L: Erik Hanson (0-1) | Fourth | 2 out |
| Wednesday, April 8 |
| » Lost to Rangers (3-0), 13-1 | Kingdome (0-3) | 0-3 | Lost 3 |
| » W: Jose Guzman (1-0) L: Russ Swan (0-1) | Fifth | 3 out |
| Thursday, April 9 |
| » Lost to Rangers (4-0), 9-1 | Kingdome (0-4) | 0-4 | Lost 4 |
| » W: Jeff Robinson (1-0) L: Dave Fleming (0-1) | Fifth | 4 out |
| Friday, April 10 |
| » Defeated Royals (0-4), 9-3 | Kingdome (1-4) | 1-4 | |
| » W: Rich DeLucia (1-0) L: Mark Davis (0-1) | Fourth | 3½ out |
| Saturday, April 11 |
| » Defeated Royals (0-5), 1-0 | Kingdome (2-4) | 2-4 | Won 2 |
| » W: Randy Johnson (1-0) L: Kevin Appier (0-1) | Fourth | 3½ out |
| Sunday, April 12 |
| » Defeated Royals (0-6), 2-1 | Kingdome (3-4) | 3-4 | Won 3 |
| » W: Erik Hanson (1-1) L: Mike Boddicker (0-1) S: Mike Schooler (1) | Fifth | 3 out |
| Monday, April 13 |
| » Lost to White Sox (5-2), 1-0 | Comiskey Park II (0-1) | 3-5 | |
| » W: Greg Hibbard (2-0) L: Russ Swan (0-2) S: Bobby Thigpen (3) | Sixth | 3½ out |
| Wednesday, April 15 |
| » Defeated White Sox (5-3), 6-0 | Comiskey Park II (1-1) | 4-5 | |
| » W: Dave Fleming (1-1) L: Kirk McCaskill (1-1) | Fourth | 3 out |
| Thursday, April 16 |
| » Lost to White Sox (6-3), 5-4 | Comiskey Park II (1-2) | 4-6 | |
| » W: Alex Fernandez (1-1) L: Rich DeLucia (1-1) | Fifth | 4 out |
| » Major-league debuts: Jeff Nelson (Mariners) |
| Friday, April 17 |
| » Lost to Brewers (5-4), 5-1 | County Stadium (0-1) | 4-7 | Lost 2 |
| » W: Bill Wegman (1-1) L: Erik Hanson (1-2) | Sixth | 4 out |
| Saturday, April 18 |
| » Defeated Brewers (5-5), 5-3 | County Stadium (1-1) | 5-7 | |
| » W: Russ Swan (1-2) L: Dan Plesac (1-1) S: Mike Schooler (2) | Fifth | 4 out |
| Sunday, April 19 |
| » Defeated Brewers (5-6), 12-9 | County Stadium (2-1) | 6-7 | Won 2 |
| » W: Calvin Jones (1-0) L: Bruce Ruffin (1-1) S: Mike Schooler (3) | Fifth | 3 out |
| Monday, April 20 |
| » Defeated Twins (4-8), 2-0 | Kingdome (4-4) | 7-7 | Won 3 |
| » W: Randy Johnson (2-0) L: Kevin Tapani (1-1) | Fifth | 3 out |
| Tuesday, April 21 |
| » Lost to Twins (5-8), 5-2 | Kingdome (4-5) | 7-8 | |
| » W: Pat Mahomes (1-0) L: Rich DeLucia (1-2) S: Rick Aguilera (3) | Fifth | 3 out |
| Wednesday, April 22 |
| » Lost to Twins (6-8), 8-1 | Kingdome (4-6) | 7-9 | Lost 2 |
| » W: Bill Krueger (3-0) L: Erik Hanson (1-3) | Fifth | 4 out |
| Thursday, April 23 |
| » Defeated Twins (6-9), 3-2 | Kingdome (5-6) | 8-9 | |
| » W: Russ Swan (2-2) L: Scott Erickson (0-2) S: Mike Schooler (4) | Fifth | 3½ out |
| Friday, April 24 |
| » Defeated Angels (8-8), 7-2 | Anaheim Stadium (1-0) | 9-9 | Won 2 |
| » W: Dave Fleming (2-1) L: Jim Abbott (1-2) | Fourth | 2½ out |
| Saturday, April 25 |
| » Defeated Angels (8-9), 10-6 | Anaheim Stadium (2-0) | 10-9 | Won 3 |
| » W: Randy Johnson (3-0) L: Joe Grahe (1-2) S: Mike Schooler (5) | Third | 2½ out |
| Sunday, April 26 |
| » Lost to Angels (9-9), 7-5 | Anaheim Stadium (2-1) | 10-10 | |
| » W: Scott Bailes (1-0) L: Jeff Nelson (0-1) S: Bryan Harvey (5) | Fifth | 2½ out |
| Tuesday, April 28 |
| » Lost to Tigers (7-13), 4-1 | Tiger Stadium (0-1) | 10-11 | Lost 2 |
| » W: Bill Gullickson (3-2) L: Russ Swan (2-3) | Fifth | 3½ out |
| Friday, May 1 |
| » Lost to Orioles (14-8), 15-1 | Oriole Park at Camden Yards (0-1) | 10-12 | Lost 3 |
| » W: Ben McDonald (3-0) L: Randy Johnson (3-1) | Fifth | 4½ out |
| Saturday, May 2 |
| » Lost to Orioles (15-8), 4-2 | Oriole Park at Camden Yards (0-2) | 10-13 | Lost 4 |
| » W: Rick Sutcliffe (4-2) L: Erik Hanson (1-4) S: Gregg Olson (4) | Fifth | 4½ out |
| Sunday, May 3 |
| » Lost to Orioles (16-8), 8-6 | Oriole Park at Camden Yards (0-3) | 10-14 | Lost 5 |
| » W: Mike Mussina (4-0) L: Rich DeLucia (1-3) S: Gregg Olson (5) | Sixth | 4½ out |
| Monday, May 4 |
| » Lost to Yankees (15-10), 7-5 | Kingdome (5-7) | 10-15 | Lost 6 |
| » W: Tim Leary (3-1) L: Russ Swan (2-4) S: Steve Howe (3) | Sixth | 4½ out |
| Tuesday, May 5 |
| » Defeated Yankees (15-11), 7-4 | Kingdome (6-7) | 11-15 | |
| » W: Dave Fleming (3-1) L: Greg Cadaret (2-2) | Sixth | 4 out |
| Wednesday, May 6 |
| » Lost to Blue Jays (20-9), 12-4 | Kingdome (6-8) | 11-16 | |
| » W: Jimmy Key (2-1) L: Randy Johnson (3-2) | Sixth | 5 out |
| Thursday, May 7 |
| » Lost to Blue Jays (21-9), 8-7 | Kingdome (6-9) | 11-17 | Lost 2 |
| » W: Pat Hentgen (3-0) L: Mike Schooler (0-2) S: Tom Henke (4) | Sixth | 6 out |
| Friday, May 8 |
| » Lost to Tigers (12-17), 7-6 | Kingdome (6-10) | 11-18 | Lost 3 |
| » W: Les Lancaster (2-1) L: Mike Schooler (0-3) S: Mike Henneman (5) | Sixth | 7 out |
| Saturday, May 9 |
| » Lost to Tigers (13-17), 13-0 | Kingdome (6-11) | 11-19 | Lost 4 |
| » W: Bill Gullickson (5-2) L: Russ Swan (2-5) | Sixth | 7½ out |
| Sunday, May 10 |
| » Defeated Tigers (13-18), 6-2 | Kingdome (7-11) | 12-19 | |
| » W: Dave Fleming (4-1) L: Scott Aldred (0-3) | Sixth | 7½ out |
| Tuesday, May 12 |
| » Lost to Yankees (16-16), 3-1 | Yankee Stadium (0-1) | 12-20 | |
| » W: Melido Perez (3-3) L: Randy Johnson (3-3) S: Steve Howe (4) | Sixth | 7½ out |
| Wednesday, May 13 |
| » Lost to Yankees (17-16), 12-4 | Yankee Stadium (0-2) | 12-21 | Lost 2 |
| » W: Scott Sanderson (3-2) L: Erik Hanson (1-5) | Sixth | 8 out |
| » Major-league debuts: Bert Heffernan (Mariners) |
| Thursday, May 14 |
| » Lost to Blue Jays (25-11), 5-4 | Skydome (0-1) | 12-22 | Lost 3 |
| » W: Dave Stieb (2-3) L: Calvin Jones (1-1) S: David Wells (1) | Sixth | 8½ out |
| Friday, May 15 |
| » Defeated Blue Jays (25-12), 2-1 | Skydome (1-1) | 13-22 | |
| » W: Dave Fleming (5-1) L: Todd Stottlemyre (4-3) S: Mike Schooler (6) | Sixth | 7½ out |
| Saturday, May 16 |
| » Defeated Blue Jays (25-13), 7-6 | Skydome (2-1) | 14-22 | Won 2 |
| » W: Dennis Powell (1-0) L: David Wells (1-2) S: Mike Schooler (7) | Fifth | 7 out |
| Sunday, May 17 |
| » Defeated Blue Jays (25-14), 3-2 | Skydome (3-1) | 15-22 | Won 3 |
| » W: Randy Johnson (4-3) L: Jimmy Key (3-2) S: Mike Schooler (8) | Fifth | 6½ out |
| Monday, May 18 |
| » Lost to Red Sox (17-17), 3-2 | Fenway Park (0-1) | 15-23 | |
| » W: Mike Gardiner (3-1) L: Erik Hanson (1-6) S: Jeff Reardon (8) | Sixth | 7 out |
| Tuesday, May 19 |
| » Lost to Red Sox (18-17), 7-5 | Fenway Park (0-2) | 15-24 | Lost 2 |
| » W: Tom Bolton (1-1) L: Jeff Nelson (0-2) S: Jeff Reardon (9) | Sixth | 8 out |
| Wednesday, May 20 |
| » Lost to Red Sox (19-17), 6-4 | Fenway Park (0-3) | 15-25 | Lost 3 |
| » W: Roger Clemens (6-3) L: Dennis Powell (1-1) S: Jeff Reardon (10) | Sixth | 9 out |
| Friday, May 22 |
| » Defeated Indians (13-29), 2-1 | Kingdome (8-11) | 16-25 | |
| » W: Randy Johnson (5-3) L: Scott Scudder (2-5) S: Mike Schooler (9) | Sixth | 9 out |
| Saturday, May 23 |
| » Lost to Indians (14-29), 5-4 | Kingdome (8-12) | 16-26 | |
| » W: Derek Lilliquist (2-2) L: Erik Hanson (1-7) S: Steve Olin (7) | Sixth | 9 out |
| Sunday, May 24 |
| » Defeated Indians (14-30), 5-4 | Kingdome (9-12) | 17-26 | |
| » W: Calvin Jones (2-1) L: Steve Olin (0-3) | Sixth | 9 out |
| Monday, May 25 |
| » Defeated Orioles (26-17), 7-3 | Kingdome (10-12) | 18-26 | Won 2 |
| » W: Dave Fleming (6-1) L: Jose Mesa (1-5) S: Mike Schooler (10) | Sixth | 8 out |
| Tuesday, May 26 |
| » Lost to Orioles (27-17), 13-8 | Kingdome (10-13) | 18-27 | |
| » W: Rick Sutcliffe (6-4) L: Randy Johnson (5-4) | Sixth | 8 out |
| Wednesday, May 27 |
| » Defeated Orioles (27-18), 7-1 | Kingdome (11-13) | 19-27 | |
| » W: Erik Hanson (2-7) L: Ben McDonald (6-2) | Sixth | 7 out |
| Friday, May 29 |
| » Defeated Red Sox (23-20), 7-3 | Kingdome (12-13) | 20-27 | Won 2 |
| » W: Dennis Powell (2-1) L: John Dopson (1-2) | Sixth | 7½ out |
| Saturday, May 30 |
| » Defeated Red Sox (23-21), 3-0 | Kingdome (13-13) | 21-27 | Won 3 |
| » W: Dave Fleming (7-1) L: Mike Gardiner (3-3) | Sixth | 6½ out |
| Sunday, May 31 |
| » Lost to Red Sox (24-21), 7-1 | Kingdome (13-14) | 21-28 | |
| » W: Roger Clemens (8-3) L: Randy Johnson (5-5) | Sixth | 7 out |
| Tuesday, June 2 |
| » Lost to Indians (20-31), 4-3 | Cleveland Stadium (0-1) | 21-29 | Lost 2 |
| » W: Dave Otto (4-3) L: Erik Hanson (2-8) S: Steve Olin (11) | Fifth | 7½ out |
| Wednesday, June 3 |
| » Lost to Indians (21-31), 8-3 | Cleveland Stadium (0-2) | 21-30 | Lost 3 |
| » W: Scott Scudder (4-5) L: Clay Parker (0-1) | Sixth | 8½ out |
| Thursday, June 4 |
| » Defeated Indians (21-32), 10-3 | Cleveland Stadium (1-2) | 22-30 | |
| » W: Dave Fleming (8-1) L: Denis Boucher (1-1) | Sixth | 8 out |
| Friday, June 5 |
| » Lost to Royals (20-32), 6-4 | Royals Stadium (0-1) | 22-31 | |
| » W: Kevin Appier (5-3) L: Calvin Jones (2-2) S: Jeff Montgomery (11) | Sixth | 9 out |
| Saturday, June 6 |
| » Lost to Royals (21-32), 4-3 | Royals Stadium (0-2) | 22-32 | Lost 2 |
| » W: Neal Heaton (3-1) L: Mike Schooler (0-4) | Sixth | 10 out |
| Sunday, June 7 |
| » Lost to Royals (22-32), 4-1 | Royals Stadium (0-3) | 22-33 | Lost 3 |
| » W: Rick Reed (1-0) L: Erik Hanson (2-9) S: Jeff Montgomery (12) | Sixth | 10 out |
| Monday, June 8 |
| » Lost to Rangers (34-26), 14-3 | Arlington Stadium (0-1) | 22-34 | Lost 4 |
| » W: Kevin Brown (9-3) L: Clay Parker (0-2) | Seventh | 10 out |
| Tuesday, June 9 |
| » Defeated Rangers (34-27), 2-1 | Arlington Stadium (1-1) | 23-34 | |
| » W: Dave Fleming (9-1) L: Kenny Rogers (1-3) S: Mike Schooler (11) | Sixth | 10 out |
| Wednesday, June 10 |
| » Lost to Rangers (35-27), 5-3 | Arlington Stadium (1-2) | 23-35 | |
| » W: Jose Guzman (6-3) L: Randy Johnson (5-6) S: Jeff Russell (16) | Sixth | 11 out |
| Friday, June 12 |
| » Defeated Brewers (29-28), 4-1 | Kingdome (14-14) | 24-35 | |
| » W: Erik Hanson (3-9) L: Jaime Navarro (6-5) S: Russ Swan (1) | Sixth | 11 out |
| Saturday, June 13 |
| » Lost to Brewers (30-28), 8-7 | Kingdome (14-15) | 24-36 | |
| » W: Mike Fetters (2-0) L: Eric Gunderson (0-1) S: Doug Henry (10) | Seventh | 12 out |
| Sunday, June 14 |
| » Lost to Brewers (31-28), 14-4 | Kingdome (14-16) | 24-37 | Lost 2 |
| » W: Ricky Bones (3-2) L: Dave Fleming (9-2) | Seventh | 13 out |
| Monday, June 15 |
| » Defeated White Sox (29-31), 4-1 | Kingdome (15-16) | 25-37 | |
| » W: Rich DeLucia (2-3) L: Kirk McCaskill (3-6) S: Russ Swan (2) | Seventh | 13 out |
| Tuesday, June 16 |
| » Defeated White Sox (29-32), 9-6 | Kingdome (16-16) | 26-37 | Won 2 |
| » W: Eric Gunderson (1-1) L: Scott Radinsky (2-4) S: Mike Schooler (12) | Seventh | 12 out |
| » Major-league debuts: Mike Walker (Mariners) |
| Wednesday, June 17 |
| » Defeated White Sox (29-33), 2-1 | Kingdome (17-16) | 27-37 | Won 3 |
| » W: Erik Hanson (4-9) L: Charlie Hough (2-4) S: Mike Schooler (13) | Sixth | 11 out |
| Thursday, June 18 |
| » Defeated White Sox (29-34), 5-4 | Kingdome (18-16) | 28-37 | Won 4 |
| » W: Eric Gunderson (2-1) L: Wilson Alvarez (0-1) | Sixth | 10½ out |
| Friday, June 19 |
| » Defeated Twins (35-30), 1-0 | Hubert H. Humphrey Metrodome (1-0) | 29-37 | Won 5 |
| » W: Dave Fleming (10-2) L: Kevin Tapani (6-5) | Fifth | 10½ out |
| Saturday, June 20 |
| » Lost to Twins (36-30), 5-3 | Hubert H. Humphrey Metrodome (1-1) | 29-38 | |
| » W: Bill Krueger (7-1) L: Rich DeLucia (2-4) S: Rick Aguilera (19) | Sixth | 10½ out |
| Sunday, June 21 |
| » Lost to Twins (37-30), 5-0 | Hubert H. Humphrey Metrodome (1-2) | 29-39 | Lost 2 |
| » W: Willie Banks (1-1) L: Mike Walker (0-1) S: Tom Edens (2) | Sixth | 10½ out |
| Monday, June 22 |
| » Lost to Athletics (40-28), 7-2 | Oakland-Alameda County Stadium (0-1) | 29-40 | Lost 3 |
| » W: Ron Darling (7-4) L: Erik Hanson (4-10) S: Dennis Eckersley (24) | Sixth | 11½ out |
| Tuesday, June 23 |
| » Lost to Athletics (41-28), 12-7 | Oakland-Alameda County Stadium (0-2) | 29-41 | Lost 4 |
| » W: Joe Slusarski (5-4) L: Randy Kramer (0-1) | Seventh | 12½ out |
| Wednesday, June 24 |
| » Lost to Athletics (42-28), 7-2 | Oakland-Alameda County Stadium (0-3) | 29-42 | Lost 5 |
| » W: Dave Stewart (7-5) L: Dave Fleming (10-3) | Seventh | 13½ out |
| Thursday, June 25 |
| » Defeated Angels (30-41), 13-4 | Kingdome (19-16) | 30-42 | |
| » W: Rich DeLucia (3-4) L: Julio Valera (4-6) | Sixth | 13½ out |
| Friday, June 26 |
| » Lost to Angels (31-41), 10-1 | Kingdome (19-17) | 30-43 | |
| » W: Jim Abbott (4-9) L: Mike Walker (0-2) | Sixth | 13½ out |
| Saturday, June 27 |
| » Lost to Angels (32-41), 2-1 | Kingdome (19-18) | 30-44 | Lost 2 |
| » W: Mark Langston (8-5) L: Randy Johnson (5-7) | Seventh | 13½ out |
| Sunday, June 28 |
| » Defeated Angels (32-42), 9-2 | Kingdome (20-18) | 31-44 | |
| » W: Erik Hanson (5-10) L: Bert Blyleven (3-2) | Sixth | 12½ out |
| Monday, June 29 |
| » Lost to Athletics (44-31), 5-4 | Kingdome (20-19) | 31-45 | |
| » W: Vince Horsman (2-0) L: Mike Schooler (0-5) S: Dennis Eckersley (26) | Sixth | 13½ out |
| Tuesday, June 30 |
| » Lost to Athletics (45-31), 4-2 | Kingdome (20-20) | 31-46 | Lost 2 |
| » W: Bob Welch (5-4) L: Jeff Nelson (0-3) S: Dennis Eckersley (27) | Sixth | 14½ out |
| Wednesday, July 1 |
| » Lost to Athletics (46-31), 3-1 | Kingdome (20-21) | 31-47 | Lost 3 |
| » W: Mike Moore (8-7) L: Mark Grant (0-1) S: Dennis Eckersley (28) | Sixth | 15½ out |
| Friday, July 3 |
| » Lost to Tigers (36-43), 6-4 | Tiger Stadium (0-2) | 31-48 | Lost 4 |
| » W: Walt Terrell (2-8) L: Randy Johnson (5-8) S: Mike Henneman (13) | Sixth | 15 out |
| » Defeated Tigers (36-44), 11-0 | Tiger Stadium (1-2) | 32-48 | |
| » W: Erik Hanson (6-10) L: Les Lancaster (2-2) | Sixth | 15 out |
| Saturday, July 4 |
| » Defeated Tigers (36-45), 4-3 | Tiger Stadium (2-2) | 33-48 | Won 2 |
| » W: Mike Schooler (1-5) L: Mike Henneman (0-4) S: Russ Swan (3) | Sixth | 15 out |
| Sunday, July 5 |
| » Lost to Tigers (37-45), 8-5 | Tiger Stadium (2-3) | 33-49 | |
| » W: Walt Terrell (3-8) L: Rich DeLucia (3-5) S: John Doherty (2) | Sixth | 16 out |
| Monday, July 6 |
| » Lost to Tigers (38-45), 5-4 | Tiger Stadium (2-4) | 33-50 | Lost 2 |
| » W: John Kiely (2-0) L: Mike Walker (0-3) | Sixth | 17 out |
| Tuesday, July 7 |
| » Lost to Blue Jays (51-31), 4-3 | Skydome (3-2) | 33-51 | Lost 3 |
| » W: Duane Ward (5-4) L: Jeff Nelson (0-4) | Sixth | 17 out |
| Wednesday, July 8 |
| » Lost to Blue Jays (52-31), 6-0 | Skydome (3-3) | 33-52 | Lost 4 |
| » W: Jimmy Key (6-6) L: Erik Hanson (6-11) | Sixth | 18 out |
| Thursday, July 9 |
| » Lost to Yankees (42-42), 7-6 | Yankee Stadium (0-3) | 33-53 | Lost 5 |
| » W: Scott Kamieniecki (2-6) L: Randy Johnson (5-9) S: John Habyan (6) | Sixth | 18 out |
| Friday, July 10 |
| » Defeated Yankees (42-43), 5-2 | Yankee Stadium (1-3) | 34-53 | |
| » W: Dave Fleming (11-3) L: Scott Sanderson (8-6) S: Russ Swan (4) | Sixth | 18 out |
| Saturday, July 11 |
| » Defeated Yankees (42-44), 5-3 | Yankee Stadium (2-3) | 35-53 | Won 2 |
| » W: Russ Swan (3-5) L: John Habyan (3-3) | Sixth | 18 out |
| Sunday, July 12 |
| » Defeated Yankees (42-45), 7-6 | Yankee Stadium (3-3) | 36-53 | Won 3 |
| » W: Erik Hanson (7-11) L: Greg Cadaret (4-7) S: Russ Swan (5) | Sixth | 18 out |
| » Major-league debuts: Jerry Nielsen (Yankees) |
| Thursday, July 16 |
| » Lost to Blue Jays (54-34), 7-2 | Kingdome (20-22) | 36-54 | |
| » W: Jack Morris (11-3) L: Randy Johnson (5-10) | Seventh | 19 out |
| Friday, July 17 |
| » Defeated Blue Jays (54-35), 8-6 | Kingdome (21-22) | 37-54 | |
| » W: Erik Hanson (8-11) L: Jimmy Key (6-7) S: Russ Swan (6) | Seventh | 19 out |
| Saturday, July 18 |
| » Lost to Blue Jays (55-35), 3-0 | Kingdome (21-23) | 37-55 | |
| » W: Juan Guzman (12-2) L: Dave Fleming (11-4) S: Tom Henke (16) | Seventh | 19 out |
| Sunday, July 19 |
| » Lost to Blue Jays (56-35), 8-4 | Kingdome (21-24) | 37-56 | Lost 2 |
| » W: David Wells (5-4) L: Rich DeLucia (3-6) | Seventh | 20 out |
| » Major-league debuts: Kerry Woodson (Mariners) |
| Monday, July 20 |
| » Lost to Tigers (44-50), 6-4 | Kingdome (21-25) | 37-57 | Lost 3 |
| » W: Walt Terrell (4-8) L: Mark Grant (0-2) S: Kurt Knudsen (4) | Seventh | 20 out |
| Tuesday, July 21 |
| » Lost to Tigers (45-50), 6-2 | Kingdome (21-26) | 37-58 | Lost 4 |
| » W: Frank Tanana (9-6) L: Randy Johnson (5-11) | Seventh | 20 out |
| Wednesday, July 22 |
| » Lost to Tigers (46-50), 3-2 | Kingdome (21-27) | 37-59 | Lost 5 |
| » W: Bill Gullickson (11-6) L: Erik Hanson (8-12) S: Kurt Knudsen (5) | Seventh | 21 out |
| Thursday, July 23 |
| » Lost to Yankees (46-49), 5-4 | Kingdome (21-28) | 37-60 | Lost 6 |
| » W: Tim Burke (3-3) L: Russ Swan (3-6) S: John Habyan (7) | Seventh | 21½ out |
| Friday, July 24 |
| » Lost to Yankees (47-49), 8-7 | Kingdome (21-29) | 37-61 | Lost 7 |
| » W: Steve Farr (1-1) L: Dennis Powell (2-2) | Seventh | 22 out |
| Saturday, July 25 |
| » Defeated Yankees (47-50), 8-2 | Kingdome (22-29) | 38-61 | |
| » W: Mark Grant (1-2) L: Shawn Hillegas (1-4) S: Jeff Nelson (1) | Seventh | 22 out |
| Sunday, July 26 |
| » Defeated Yankees (47-51), 8-5 | Kingdome (23-29) | 39-61 | Won 2 |
| » W: Randy Johnson (6-11) L: Melido Perez (9-9) S: Russ Swan (7) | Sixth | 22 out |
| Monday, July 27 |
| » Lost to Angels (44-55), 3-0 | Anaheim Stadium (2-2) | 39-62 | |
| » W: Chuck Finley (3-9) L: Erik Hanson (8-13) S: Joe Grahe (9) | Seventh | 22 out |
| Tuesday, July 28 |
| » Defeated Angels (44-56), 8-1 | Anaheim Stadium (3-2) | 40-62 | |
| » W: Dave Fleming (12-4) L: Mark Langston (9-9) | Seventh | 21 out |
| Wednesday, July 29 |
| » Defeated Angels (44-57), 8-0 | Anaheim Stadium (4-2) | 41-62 | Won 2 |
| » W: Brian Fisher (1-0) L: Bert Blyleven (4-5) | Sixth | 20 out |
| Thursday, July 30 |
| » Lost to Angels (45-57), 6-5 | Anaheim Stadium (4-3) | 41-63 | |
| » W: Mark Eichhorn (2-4) L: Russ Swan (3-7) S: Joe Grahe (10) | Seventh | 20½ out |
| Friday, July 31 |
| » Defeated White Sox (50-51), 6-3 | Comiskey Park II (2-2) | 42-63 | |
| » W: Randy Johnson (7-11) L: Charlie Hough (4-7) S: Russ Swan (8) | Seventh | 20 out |
| Saturday, August 1 |
| » Lost to White Sox (51-51), 8-1 | Comiskey Park II (2-3) | 42-64 | |
| » W: Kirk McCaskill (7-8) L: Erik Hanson (8-14) S: Greg Hibbard (1) | Seventh | 21 out |
| Sunday, August 2 |
| » Lost to White Sox (52-51), 7-4 | Comiskey Park II (2-4) | 42-65 | Lost 2 |
| » W: Jack McDowell (15-5) L: Dave Fleming (12-5) S: Scott Radinsky (9) | Seventh | 22 out |
| Tuesday, August 4 |
| » Lost to Brewers (56-49), 5-2 | County Stadium (2-2) | 42-66 | Lost 3 |
| » W: Chris Bosio (9-5) L: Brian Fisher (1-1) S: Doug Henry (21) | Sixth | 22 out |
| Wednesday, August 5 |
| » Lost to Brewers (57-49), 8-1 | County Stadium (2-3) | 42-67 | Lost 4 |
| » W: Bill Wegman (10-8) L: Randy Johnson (7-12) | Seventh | 23 out |
| Thursday, August 6 |
| » Lost to Brewers (58-49), 4-2 | County Stadium (2-4) | 42-68 | Lost 5 |
| » W: Jaime Navarro (12-7) L: Mark Grant (1-3) S: Doug Henry (22) | Seventh | 24 out |
| » Major-league debuts: Shawn Barton (Mariners) |
| Friday, August 7 |
| » Lost to Rangers (56-56), 7-6 | Kingdome (23-30) | 42-69 | Lost 6 |
| » W: Todd Burns (3-4) L: Russ Swan (3-8) S: Edwin Nunez (3) | Seventh | 25 out |
| Saturday, August 8 |
| » Lost to Rangers (57-56), 7-3 | Kingdome (23-31) | 42-70 | Lost 7 |
| » W: Jose Guzman (9-9) L: Kerry Woodson (0-1) | Seventh | 26 out |
| Sunday, August 9 |
| » Defeated Rangers (57-57), 6-5 | Kingdome (24-31) | 43-70 | |
| » W: Calvin Jones (3-2) L: Matt Whiteside (0-1) | Seventh | 25 out |
| Monday, August 10 |
| » Defeated Royals (50-62), 3-1 | Kingdome (25-31) | 44-70 | Won 2 |
| » W: Randy Johnson (8-12) L: Luis Aquino (2-3) | Seventh | 25 out |
| Tuesday, August 11 |
| » Lost to Royals (51-62), 9-6 | Kingdome (25-32) | 44-71 | |
| » W: Hipolito Pichardo (6-4) L: Erik Hanson (8-15) S: Jeff Montgomery (29) | Seventh | 25 out |
| Wednesday, August 12 |
| » Defeated Royals (51-63), 6-3 | Kingdome (26-32) | 45-71 | |
| » W: Dave Fleming (13-5) L: Dennis Moeller (0-3) S: Jeff Nelson (2) | Seventh | 25 out |
| Thursday, August 13 |
| » Major-league debuts: Damion Easley (Angels) |
| Friday, August 14 |
| » Lost to Twins (67-49), 9-6 | Kingdome (26-33) | 45-72 | |
| » W: David West (1-1) L: Calvin Jones (3-3) S: Rick Aguilera (32) | Seventh | 25½ out |
| Saturday, August 15 |
| » Defeated Twins (67-50), 3-2 | Kingdome (27-33) | 46-72 | |
| » W: Randy Johnson (9-12) L: Tom Edens (5-2) | Seventh | 25½ out |
| Sunday, August 16 |
| » Defeated Twins (67-51), 8-7 | Kingdome (28-33) | 47-72 | Won 2 |
| » W: Jeff Nelson (1-4) L: Mark Guthrie (2-3) | Seventh | 25½ out |
| Tuesday, August 18 |
| » Defeated Orioles (66-53), 8-3 | Oriole Park at Camden Yards (1-3) | 48-72 | Won 3 |
| » W: Dave Fleming (14-5) L: Ben McDonald (12-8) S: Jeff Nelson (3) | Seventh | 24½ out |
| Wednesday, August 19 |
| » Defeated Orioles (66-54), 10-8 | Oriole Park at Camden Yards (2-3) | 49-72 | Won 4 |
| » W: Mark Grant (2-3) L: Arthur Rhodes (4-3) S: Russ Swan (9) | Seventh | 23½ out |
| » Major-league debuts: Bret Boone (Mariners) |
| Thursday, August 20 |
| » Lost to Orioles (67-54), 2-1 | Oriole Park at Camden Yards (2-4) | 49-73 | |
| » W: Storm Davis (5-2) L: Mike Schooler (1-6) | Seventh | 24½ out |
| Friday, August 21 |
| » Defeated Red Sox (55-67), 5-2 | Fenway Park (1-3) | 50-73 | |
| » W: Randy Johnson (10-12) L: Frank Viola (10-10) | Seventh | 23½ out |
| Saturday, August 22 |
| » Lost to Red Sox (56-67), 10-8 | Fenway Park (1-4) | 50-74 | |
| » W: Greg Harris (3-7) L: Shawn Barton (0-1) S: Jeff Reardon (26) | Seventh | 24½ out |
| Sunday, August 23 |
| » Defeated Red Sox (56-68), 9-3 | Fenway Park (2-4) | 51-74 | |
| » W: Dennis Powell (3-2) L: Roger Clemens (15-8) | Seventh | 24½ out |
| Monday, August 24 |
| » Major-league debuts: Todd Revenig (Athletics) |
| Tuesday, August 25 |
| » Defeated Indians (58-67), 6-0 | Kingdome (29-33) | 52-74 | Won 2 |
| » W: Dave Fleming (15-5) L: Charles Nagy (13-9) | Seventh | 24 out |
| Wednesday, August 26 |
| » Lost to Indians (59-67), 6-3 | Kingdome (29-34) | 52-75 | |
| » W: Eric Plunk (5-2) L: Russ Swan (3-9) S: Steve Olin (23) | Seventh | 24 out |
| Thursday, August 27 |
| » Defeated Indians (59-68), 6-2 | Kingdome (30-34) | 53-75 | |
| » W: Brian Fisher (2-1) L: Dennis Cook (5-6) | Seventh | 23½ out |
| Friday, August 28 |
| » Defeated Orioles (70-58), 6-4 | Kingdome (31-34) | 54-75 | Won 2 |
| » W: Tim Leary (6-6) L: Ben McDonald (12-10) S: Jeff Nelson (4) | Seventh | 23½ out |
| Saturday, August 29 |
| » Lost to Orioles (71-58), 4-0 | Kingdome (31-35) | 54-76 | |
| » W: Arthur Rhodes (5-4) L: Mark Grant (2-4) S: Gregg Olson (30) | Seventh | 24½ out |
| Sunday, August 30 |
| » Lost to Orioles (72-58), 2-0 | Kingdome (31-36) | 54-77 | Lost 2 |
| » W: Rick Sutcliffe (14-11) L: Dave Fleming (15-6) S: Gregg Olson (31) | Seventh | 25½ out |
| Monday, August 31 |
| » Defeated Red Sox (60-71), 15-2 | Kingdome (32-36) | 55-77 | |
| » W: Randy Johnson (11-12) L: Frank Viola (11-11) | Seventh | 24½ out |
| » Major-league debuts: Ken Ryan (Red Sox) |
| Tuesday, September 1 |
| » Defeated Red Sox (60-72), 4-3 | Kingdome (33-36) | 56-77 | Won 2 |
| » W: Mike Schooler (2-6) L: Greg Harris (3-8) | Seventh | 23½ out |
| Wednesday, September 2 |
| » Lost to Red Sox (61-72), 5-3 | Kingdome (33-37) | 56-78 | |
| » W: Roger Clemens (17-8) L: Tim Leary (6-7) | Seventh | 23½ out |
| Friday, September 4 |
| » Lost to Indians (61-73), 7-0 | Cleveland Stadium (1-3) | 56-79 | Lost 2 |
| » W: Jose Mesa (6-10) L: Dave Fleming (15-7) | Seventh | 23½ out |
| Saturday, September 5 |
| » Lost to Indians (62-73), 5-4 | Cleveland Stadium (1-4) | 56-80 | Lost 3 |
| » W: Eric Plunk (6-3) L: Russ Swan (3-10) | Seventh | 23½ out |
| Sunday, September 6 |
| » Lost to Indians (63-73), 12-9 | Cleveland Stadium (1-5) | 56-81 | Lost 4 |
| » W: Steve Olin (7-4) L: Mike Schooler (2-7) | Seventh | 24½ out |
| Monday, September 7 |
| » Lost to Twins (76-62), 4-2 | Hubert H. Humphrey Metrodome (1-3) | 56-82 | Lost 5 |
| » W: Scott Erickson (11-10) L: Tim Leary (6-8) S: Rick Aguilera (37) | Seventh | 24½ out |
| Tuesday, September 8 |
| » Lost to Twins (77-62), 8-4 | Hubert H. Humphrey Metrodome (1-4) | 56-83 | Lost 6 |
| » W: Gary Wayne (3-2) L: Calvin Jones (3-4) | Seventh | 25½ out |
| Wednesday, September 9 |
| » Lost to Twins (78-62), 6-2 | Hubert H. Humphrey Metrodome (1-5) | 56-84 | Lost 7 |
| » W: Kevin Tapani (15-10) L: Dave Fleming (15-8) S: Mark Guthrie (4) | Seventh | 26½ out |
| Thursday, September 10 |
| » Lost to Athletics (83-57), 6-4 | Oakland-Alameda County Stadium (0-4) | 56-85 | Lost 8 |
| » W: Ron Darling (13-9) L: Randy Johnson (11-13) S: Dennis Eckersley (44) | Seventh | 27½ out |
| Friday, September 11 |
| » Lost to Athletics (84-57), 4-3 | Oakland-Alameda County Stadium (0-5) | 56-86 | Lost 9 |
| » W: Jeff Russell (3-3) L: Jeff Nelson (1-5) | Seventh | 28½ out |
| Saturday, September 12 |
| » Lost to Athletics (85-57), 5-4 | Oakland-Alameda County Stadium (0-6) | 56-87 | Lost 10 |
| » W: Mike Moore (14-11) L: Tim Leary (6-9) S: Dennis Eckersley (45) | Seventh | 29½ out |
| Sunday, September 13 |
| » Lost to Athletics (86-57), 3-1 | Oakland-Alameda County Stadium (0-7) | 56-88 | Lost 11 |
| » W: Kelly Downs (6-7) L: Erik Hanson (8-16) S: Jeff Russell (29) | Seventh | 30½ out |
| Tuesday, September 15 |
| » Lost to Angels (65-79), 9-0 | Kingdome (33-38) | 56-89 | Lost 12 |
| » W: Chuck Finley (5-12) L: Dave Fleming (15-9) | Seventh | 32 out |
| Wednesday, September 16 |
| » Lost to Angels (66-79), 2-1 | Kingdome (33-39) | 56-90 | Lost 13 |
| » W: Joe Grahe (5-4) L: Calvin Jones (3-5) S: Steve Frey (2) | Seventh | 33 out |
| Friday, September 18 |
| » Lost to Athletics (90-57), 7-4 | Kingdome (33-40) | 56-91 | Lost 14 |
| » W: Mike Moore (15-11) L: Brian Fisher (2-2) S: Dennis Eckersley (48) | Seventh | 34 out |
| Saturday, September 19 |
| » Defeated Athletics (90-58), 6-4 | Kingdome (34-40) | 57-91 | |
| » W: Tim Leary (7-9) L: Bob Welch (10-6) S: Jeff Nelson (5) | Seventh | 33 out |
| Sunday, September 20 |
| » Lost to Athletics (91-58), 4-2 | Kingdome (34-41) | 57-92 | |
| » W: Dave Stewart (12-9) L: Erik Hanson (8-17) S: Dennis Eckersley (49) | Seventh | 34 out |
| Monday, September 21 |
| » Lost to Royals (66-83), 3-0 | Royals Stadium (0-4) | 57-93 | Lost 2 |
| » W: Luis Aquino (3-5) L: Dave Fleming (15-10) S: Jeff Montgomery (37) | Seventh | 35 out |
| Tuesday, September 22 |
| » Lost to Royals (67-83), 3-0 | Royals Stadium (0-5) | 57-94 | Lost 3 |
| » W: Chris Haney (4-4) L: Randy Johnson (1 |