| Tuesday, April 7 |
| » Lost to White Sox (1-0), 10-4 | Anaheim Stadium (0-1) | 0-1 | |
| » W: Jack McDowell (1-0) L: Mark Langston (0-1) S: Wilson Alvarez (1) | Third | 1½ out |
| Wednesday, April 8 |
| » Lost to White Sox (2-0), 4-3 | Anaheim Stadium (0-2) | 0-2 | Lost 2 |
| » W: Greg Hibbard (1-0) L: Jim Abbott (0-1) S: Bobby Thigpen (1) | Fourth | 2½ out |
| » Major-league debuts: Chad Curtis (Angels) |
| Thursday, April 9 |
| » Lost to White Sox (3-0), 7-6 | Anaheim Stadium (0-3) | 0-3 | Lost 3 |
| » W: Kirk McCaskill (1-0) L: Joe Grahe (0-1) S: Scott Radinsky (1) | Fourth | 3½ out |
| Friday, April 10 |
| » Lost to Brewers (2-2), 5-4 | Anaheim Stadium (0-4) | 0-4 | Lost 4 |
| » W: Dan Plesac (1-0) L: Bryan Harvey (0-1) S: Doug Henry (1) | Fifth | 4 out |
| Saturday, April 11 |
| » Defeated Brewers (2-3), 4-1 | Anaheim Stadium (1-4) | 1-4 | |
| » W: Don Robinson (1-0) L: Bill Wegman (0-1) S: Bryan Harvey (1) | Fifth | 4 out |
| Sunday, April 12 |
| » Defeated Brewers (2-4), 13-9 | Anaheim Stadium (2-4) | 2-4 | Won 2 |
| » W: Mark Langston (1-1) L: Chris Bosio (0-1) | Sixth | 3½ out |
| Monday, April 13 |
| » Defeated Rangers (6-2), 3-0 | Arlington Stadium (1-0) | 3-4 | Won 3 |
| » W: Jim Abbott (1-1) L: Jose Guzman (1-1) S: Bryan Harvey (2) | Fifth | 3 out |
| Tuesday, April 14 |
| » Defeated Rangers (6-3), 8-1 | Arlington Stadium (2-0) | 4-4 | Won 4 |
| » W: Joe Grahe (1-1) L: Jeff Robinson (1-1) | Fourth | 2 out |
| Wednesday, April 15 |
| » Lost to Rangers (7-3), 3-2 | Arlington Stadium (2-1) | 4-5 | |
| » W: Bobby Witt (1-1) L: Julio Valera (0-1) S: Jeff Russell (2) | Fourth | 3 out |
| Thursday, April 16 |
| » Defeated Rangers (7-4), 3-2 | Arlington Stadium (3-1) | 5-5 | |
| » W: Chuck Crim (1-0) L: Jeff Russell (1-1) S: Bryan Harvey (3) | Fourth | 3 out |
| Friday, April 17 |
| » Defeated Royals (1-10), 8-1 | Royals Stadium (1-0) | 6-5 | Won 2 |
| » W: Scott Lewis (1-0) L: Mike Boddicker (0-2) | Fourth | 2 out |
| Saturday, April 18 |
| » Defeated Royals (1-11), 5-3 | Royals Stadium (2-0) | 7-5 | Won 3 |
| » W: Steve Frey (1-0) L: Jeff Montgomery (0-2) | Fourth | 2 out |
| Monday, April 20 |
| » Lost to Athletics (10-4), 4-3 | Oakland-Alameda County Stadium (0-1) | 7-6 | |
| » W: Dennis Eckersley (1-0) L: Chuck Crim (1-1) | Fourth | 2½ out |
| Tuesday, April 21 |
| » Defeated Athletics (10-5), 3-2 | Oakland-Alameda County Stadium (1-1) | 8-6 | |
| » W: Julio Valera (1-1) L: Dave Stewart (1-1) S: Bryan Harvey (4) | Fourth | 1½ out |
| Wednesday, April 22 |
| » Lost to Athletics (11-5), 10-4 | Oakland-Alameda County Stadium (1-2) | 8-7 | |
| » W: Mike Moore (3-0) L: Chuck Finley (0-1) | Fourth | 2½ out |
| » Major-league debuts: Henry Mercedes (Athletics) |
| Friday, April 24 |
| » Lost to Mariners (9-9), 7-2 | Anaheim Stadium (2-5) | 8-8 | Lost 2 |
| » W: Dave Fleming (2-1) L: Jim Abbott (1-2) | Third | 2½ out |
| Saturday, April 25 |
| » Lost to Mariners (10-9), 10-6 | Anaheim Stadium (2-6) | 8-9 | Lost 3 |
| » W: Randy Johnson (3-0) L: Joe Grahe (1-2) S: Mike Schooler (5) | Fifth | 3½ out |
| Sunday, April 26 |
| » Defeated Mariners (10-10), 7-5 | Anaheim Stadium (3-6) | 9-9 | |
| » W: Scott Bailes (1-0) L: Jeff Nelson (0-1) S: Bryan Harvey (5) | Fourth | 2½ out |
| Tuesday, April 28 |
| » Defeated Blue Jays (15-6), 9-5 | Skydome (1-0) | 10-9 | Won 2 |
| » W: Chuck Finley (1-1) L: Dave Stieb (0-2) | Fourth | 2½ out |
| Wednesday, April 29 |
| » Lost to Blue Jays (16-6), 1-0 | Skydome (1-1) | 10-10 | |
| » W: Todd Stottlemyre (3-1) L: Jim Abbott (1-3) | Fourth | 2½ out |
| Thursday, April 30 |
| » Defeated Indians (8-15), 8-5 | Cleveland Stadium (1-0) | 11-10 | |
| » W: Joe Grahe (2-2) L: Jeff Shaw (0-1) S: Bryan Harvey (6) | Fourth | 2½ out |
| Friday, May 1 |
| » Defeated Indians (8-16), 7-5 | Cleveland Stadium (2-0) | 12-10 | Won 2 |
| » W: Mark Langston (2-1) L: Scott Scudder (1-3) S: Bryan Harvey (7) | Fourth | 2½ out |
| Saturday, May 2 |
| » Lost to Indians (9-16), 3-2 | Cleveland Stadium (2-1) | 12-11 | |
| » W: Derek Lilliquist (1-0) L: Mark Eichhorn (0-1) S: Steve Olin (4) | Fourth | 2½ out |
| Sunday, May 3 |
| » Defeated Indians (9-17), 6-3 | Cleveland Stadium (3-1) | 13-11 | |
| » W: Scott Bailes (2-0) L: Derek Lilliquist (1-1) S: Bryan Harvey (8) | Fourth | 1½ out |
| Monday, May 4 |
| » Lost to Tigers (10-15), 6-2 | Tiger Stadium (0-1) | 13-12 | |
| » W: Bill Gullickson (4-2) L: Jim Abbott (1-4) | Fourth | 1½ out |
| Tuesday, May 5 |
| » Lost to Tigers (11-15), 2-1 | Tiger Stadium (0-2) | 13-13 | Lost 2 |
| » W: John Doherty (1-0) L: Mark Eichhorn (0-2) | Fourth | 2 out |
| Wednesday, May 6 |
| » Defeated Yankees (15-12), 3-2 | Anaheim Stadium (4-6) | 14-13 | |
| » W: Mark Langston (3-1) L: Melido Perez (2-3) S: Bryan Harvey (9) | Fourth | 2 out |
| Thursday, May 7 |
| » Defeated Yankees (15-13), 6-0 | Anaheim Stadium (5-6) | 15-13 | Won 2 |
| » W: Julio Valera (2-1) L: Scott Sanderson (2-2) | Third | 2 out |
| Friday, May 8 |
| » Defeated Blue Jays (21-10), 4-1 | Anaheim Stadium (6-6) | 16-13 | Won 3 |
| » W: Mark Eichhorn (1-2) L: Dave Stieb (1-3) | Third | 2 out |
| Saturday, May 9 |
| » Defeated Blue Jays (21-11), 2-1 | Anaheim Stadium (7-6) | 17-13 | Won 4 |
| » W: Jim Abbott (2-4) L: Todd Stottlemyre (4-2) S: Bryan Harvey (10) | Third | 1½ out |
| Sunday, May 10 |
| » Lost to Blue Jays (22-11), 4-1 | Anaheim Stadium (7-7) | 17-14 | |
| » W: Juan Guzman (5-0) L: Joe Grahe (2-3) | Third | 2½ out |
| Tuesday, May 12 |
| » Lost to Tigers (14-18), 4-2 | Anaheim Stadium (7-8) | 17-15 | Lost 2 |
| » W: Frank Tanana (2-3) L: Bryan Harvey (0-2) S: Mike Henneman (6) | Third | 2½ out |
| Wednesday, May 13 |
| » Defeated Tigers (14-19), 7-5 | Anaheim Stadium (8-8) | 18-15 | |
| » W: Steve Frey (2-0) L: Walt Terrell (0-5) S: Bryan Harvey (11) | Third | 2 out |
| Friday, May 15 |
| » Lost to Red Sox (15-16), 3-0 | Fenway Park (0-1) | 18-16 | |
| » W: Roger Clemens (5-3) L: Jim Abbott (2-5) | Third | 2 out |
| Saturday, May 16 |
| » Lost to Red Sox (16-16), 3-0 | Fenway Park (0-2) | 18-17 | Lost 2 |
| » W: Frank Viola (5-2) L: Julio Valera (2-2) S: Jeff Reardon (7) | Third | 2½ out |
| Sunday, May 17 |
| » Defeated Red Sox (16-17), 3-1 | Fenway Park (1-2) | 19-17 | |
| » W: Mark Langston (4-1) L: John Dopson (0-1) S: Bryan Harvey (12) | Third | 2 out |
| Monday, May 18 |
| » Lost to Yankees (20-17), 7-2 | Yankee Stadium (0-1) | 19-18 | |
| » W: Greg Cadaret (3-3) L: Chuck Finley (1-2) S: Steve Howe (5) | Fourth | 2½ out |
| Tuesday, May 19 |
| » Lost to Yankees (21-17), 5-4 | Yankee Stadium (0-2) | 19-19 | Lost 2 |
| » W: Rich Monteleone (2-0) L: Mark Eichhorn (1-3) | Fifth | 3½ out |
| Wednesday, May 20 |
| » Lost to Yankees (22-17), 3-2 | Yankee Stadium (0-3) | 19-20 | Lost 3 |
| » W: John Habyan (2-1) L: Chuck Crim (1-2) | Fifth | 4½ out |
| Friday, May 22 |
| » Lost to Orioles (25-15), 5-3 | Oriole Park at Camden Yards (0-1) | 19-21 | Lost 4 |
| » Manager: John Wathan |
| » W: Ben McDonald (6-1) L: Julio Valera (2-3) S: Gregg Olson (9) | Fifth | 5½ out |
| Saturday, May 23 |
| » Defeated Orioles (25-16), 6-2 | Oriole Park at Camden Yards (1-1) | 20-21 | |
| » W: Mark Langston (5-1) L: Rick Sutcliffe (5-4) | Fifth | 4½ out |
| Sunday, May 24 |
| » Lost to Orioles (26-16), 6-4 | Oriole Park at Camden Yards (1-2) | 20-22 | |
| » W: Bob Milacki (4-2) L: Chuck Finley (1-3) S: Gregg Olson (10) | Fifth | 5½ out |
| Tuesday, May 26 |
| » Lost to Red Sox (21-19), 4-1 | Anaheim Stadium (8-9) | 20-23 | Lost 2 |
| » W: Roger Clemens (7-3) L: Jim Abbott (2-6) S: Jeff Reardon (11) | Fifth | 5 out |
| Wednesday, May 27 |
| » Lost to Red Sox (22-19), 4-3 | Anaheim Stadium (8-10) | 20-24 | Lost 3 |
| » W: Jeff Reardon (1-0) L: Bryan Harvey (0-3) S: Danny Darwin (2) | Fifth | 5 out |
| Thursday, May 28 |
| » Lost to Red Sox (23-19), 2-1 | Anaheim Stadium (8-11) | 20-25 | Lost 4 |
| » W: Joe Hesketh (1-2) L: Mark Langston (5-2) S: Jeff Reardon (12) | Fifth | 6 out |
| Friday, May 29 |
| » Lost to Indians (18-30), 14-2 | Anaheim Stadium (8-12) | 20-26 | Lost 5 |
| » W: Denis Boucher (1-0) L: Chuck Finley (1-4) | Fifth | 7 out |
| Saturday, May 30 |
| » Defeated Indians (18-31), 3-1 | Anaheim Stadium (9-12) | 21-26 | |
| » W: Bert Blyleven (1-0) L: Jack Armstrong (1-6) S: Bryan Harvey (13) | Fifth | 6 out |
| Sunday, May 31 |
| » Lost to Indians (19-31), 4-3 | Anaheim Stadium (9-13) | 21-27 | |
| » W: Charles Nagy (6-3) L: Jim Abbott (2-7) S: Steve Olin (10) | Fifth | 6½ out |
| Monday, June 1 |
| » Lost to Orioles (30-19), 8-2 | Anaheim Stadium (9-14) | 21-28 | Lost 2 |
| » W: Ben McDonald (7-2) L: Julio Valera (2-4) S: Storm Davis (1) | Fifth | 6½ out |
| Tuesday, June 2 |
| » Lost to Orioles (31-19), 4-2 | Anaheim Stadium (9-15) | 21-29 | Lost 3 |
| » W: Mike Mussina (6-1) L: Mark Langston (5-3) S: Gregg Olson (13) | Fifth | 7½ out |
| Wednesday, June 3 |
| » Defeated Orioles (31-20), 4-3 | Anaheim Stadium (10-15) | 22-29 | |
| » W: Scott Bailes (3-0) L: Alan Mills (2-1) | Fifth | 7½ out |
| Friday, June 5 |
| » Lost to Brewers (26-25), 7-1 | County Stadium (0-1) | 22-30 | |
| » W: Chris Bosio (4-3) L: Jim Abbott (2-8) | Fifth | 8½ out |
| Saturday, June 6 |
| » Lost to Brewers (27-25), 4-3 | County Stadium (0-2) | 22-31 | Lost 2 |
| » W: Jaime Navarro (6-4) L: Bryan Harvey (0-4) S: Doug Henry (9) | Fifth | 9½ out |
| Sunday, June 7 |
| » Lost to Brewers (28-25), 10-3 | County Stadium (0-3) | 22-32 | Lost 3 |
| » W: Ricky Bones (2-2) L: Mark Langston (5-4) | Fifth | 9½ out |
| Monday, June 8 |
| » Lost to White Sox (26-27), 5-1 | Comiskey Park II (0-1) | 22-33 | Lost 4 |
| » W: Jack McDowell (8-3) L: Chuck Finley (1-5) S: Bobby Thigpen (13) | Sixth | 9½ out |
| Tuesday, June 9 |
| » Lost to White Sox (27-27), 4-2 | Comiskey Park II (0-2) | 22-34 | Lost 5 |
| » W: Greg Hibbard (6-4) L: Julio Valera (2-5) S: Scott Radinsky (2) | Seventh | 10½ out |
| Wednesday, June 10 |
| » Lost to White Sox (28-27), 3-2 | Comiskey Park II (0-3) | 22-35 | Lost 6 |
| » W: Donn Pall (3-2) L: Steve Frey (2-1) | Seventh | 11½ out |
| Thursday, June 11 |
| » Defeated White Sox (28-28), 4-0 | Comiskey Park II (1-3) | 23-35 | |
| » W: Bert Blyleven (2-0) L: Alex Fernandez (3-7) S: Joe Grahe (1) | Sixth | 11 out |
| Friday, June 12 |
| » Defeated Royals (24-34), 5-0 | Anaheim Stadium (11-15) | 24-35 | Won 2 |
| » W: Mark Langston (6-4) L: Hipolito Pichardo (1-3) | Sixth | 11 out |
| Saturday, June 13 |
| » Defeated Royals (24-35), 5-4 | Anaheim Stadium (12-15) | 25-35 | Won 3 |
| » W: Chuck Finley (2-5) L: Rick Reed (1-1) S: Mark Eichhorn (1) | Fifth | 11 out |
| Sunday, June 14 |
| » Defeated Royals (24-36), 5-1 | Anaheim Stadium (13-15) | 26-35 | Won 4 |
| » W: Julio Valera (3-5) L: Mark Gubicza (6-4) S: Steve Frey (1) | Fifth | 11 out |
| Monday, June 15 |
| » Lost to Rangers (36-30), 5-2 | Anaheim Stadium (13-16) | 26-36 | |
| » W: Todd Burns (1-0) L: Jim Abbott (2-9) S: Jeff Russell (17) | Fifth | 12 out |
| Tuesday, June 16 |
| » Defeated Rangers (36-31), 4-1 | Anaheim Stadium (14-16) | 27-36 | |
| » W: Bert Blyleven (3-0) L: Jose Guzman (6-4) S: Joe Grahe (2) | Fifth | 11 out |
| Wednesday, June 17 |
| » Defeated Rangers (36-32), 3-0 | Anaheim Stadium (15-16) | 28-36 | Won 2 |
| » W: Mark Langston (7-4) L: Nolan Ryan (0-3) | Fifth | 10 out |
| Friday, June 19 |
| » Lost to Athletics (39-26), 12-8 | Anaheim Stadium (15-17) | 28-37 | |
| » W: Dave Stewart (6-5) L: Chuck Finley (2-6) S: Dennis Eckersley (23) | Sixth | 11 out |
| Saturday, June 20 |
| » Defeated Athletics (39-27), 10-0 | Anaheim Stadium (16-17) | 29-37 | |
| » W: Julio Valera (4-5) L: Bob Welch (3-4) | Fifth | 10 out |
| Sunday, June 21 |
| » Defeated Athletics (39-28), 4-2 | Anaheim Stadium (17-17) | 30-37 | Won 2 |
| » W: Jim Abbott (3-9) L: Mike Moore (7-6) S: Joe Grahe (3) | Fifth | 9 out |
| Monday, June 22 |
| » Lost to Twins (38-30), 2-0 | Hubert H. Humphrey Metrodome (0-1) | 30-38 | |
| » W: John Smiley (7-3) L: Mark Langston (7-5) S: Rick Aguilera (20) | Fifth | 10 out |
| Tuesday, June 23 |
| » Lost to Twins (39-30), 5-3 | Hubert H. Humphrey Metrodome (0-2) | 30-39 | Lost 2 |
| » W: Scott Erickson (5-5) L: Bert Blyleven (3-1) S: Rick Aguilera (21) | Fifth | 11 out |
| Wednesday, June 24 |
| » Lost to Twins (40-30), 11-0 | Hubert H. Humphrey Metrodome (0-3) | 30-40 | Lost 3 |
| » W: Kevin Tapani (7-5) L: Chuck Finley (2-7) | Fifth | 12 out |
| Thursday, June 25 |
| » Lost to Mariners (30-42), 13-4 | Kingdome (0-1) | 30-41 | Lost 4 |
| » W: Rich DeLucia (3-4) L: Julio Valera (4-6) | Fifth | 13 out |
| Friday, June 26 |
| » Defeated Mariners (30-43), 10-1 | Kingdome (1-1) | 31-41 | |
| » W: Jim Abbott (4-9) L: Mike Walker (0-2) | Fifth | 12 out |
| Saturday, June 27 |
| » Defeated Mariners (30-44), 2-1 | Kingdome (2-1) | 32-41 | Won 2 |
| » W: Mark Langston (8-5) L: Randy Johnson (5-7) | Fifth | 11 out |
| Sunday, June 28 |
| » Lost to Mariners (31-44), 9-2 | Kingdome (2-2) | 32-42 | |
| » W: Erik Hanson (5-10) L: Bert Blyleven (3-2) | Fourth | 11 out |
| Monday, June 29 |
| » Lost to Twins (44-31), 5-1 | Anaheim Stadium (17-18) | 32-43 | Lost 2 |
| » W: Kevin Tapani (8-5) L: Chuck Finley (2-8) | Fifth | 12 out |
| Tuesday, June 30 |
| » Lost to Twins (45-31), 2-0 | Anaheim Stadium (17-19) | 32-44 | Lost 3 |
| » W: Bill Krueger (8-2) L: Julio Valera (4-7) | Fifth | 13 out |
| Wednesday, July 1 |
| » Lost to Twins (46-31), 2-1 | Anaheim Stadium (17-20) | 32-45 | Lost 4 |
| » W: Willie Banks (3-1) L: Jim Abbott (4-10) S: Rick Aguilera (23) | Fifth | 14 out |
| Friday, July 3 |
| » Lost to Blue Jays (47-31), 10-1 | Skydome (1-2) | 32-46 | Lost 5 |
| » W: Jimmy Key (5-6) L: Mark Langston (8-6) | Fifth | 14 out |
| Saturday, July 4 |
| » Lost to Blue Jays (48-31), 8-6 | Skydome (1-3) | 32-47 | Lost 6 |
| » W: Jack Morris (10-3) L: Mark Eichhorn (1-4) S: Tom Henke (14) | Seventh | 15 out |
| Sunday, July 5 |
| » Lost to Blue Jays (49-31), 6-2 | Skydome (1-4) | 32-48 | Lost 7 |
| » W: David Wells (4-3) L: Julio Valera (4-8) | Seventh | 16 out |
| Monday, July 6 |
| » Lost to Blue Jays (50-31), 3-0 | Skydome (1-5) | 32-49 | Lost 8 |
| » W: Juan Guzman (11-1) L: Jim Abbott (4-11) S: Tom Henke (15) | Seventh | 17 out |
| » Major-league debuts: Mike Butcher (Angels) |
| Tuesday, July 7 |
| » Lost to Indians (34-49), 3-1 | Cleveland Stadium (3-2) | 32-50 | Lost 9 |
| » W: Dennis Cook (2-5) L: Chuck Finley (2-9) S: Steve Olin (15) | Seventh | 17 out |
| Wednesday, July 8 |
| » Lost to Indians (35-49), 8-4 | Cleveland Stadium (3-3) | 32-51 | Lost 10 |
| » W: Charles Nagy (11-4) L: Mark Langston (8-7) | Seventh | 18 out |
| Thursday, July 9 |
| » Lost to Tigers (41-45), 5-4 | Tiger Stadium (0-3) | 32-52 | Lost 11 |
| » W: Frank Tanana (8-5) L: Bert Blyleven (3-3) S: Mike Henneman (16) | Seventh | 18 out |
| Friday, July 10 |
| » Defeated Tigers (41-46), 6-1 | Tiger Stadium (1-3) | 33-52 | |
| » W: Julio Valera (5-8) L: Buddy Groom (0-3) | Seventh | 18 out |
| Saturday, July 11 |
| » Defeated Tigers (41-47), 2-1 | Tiger Stadium (2-3) | 34-52 | Won 2 |
| » W: Chuck Crim (2-2) L: Bill Gullickson (9-6) S: Joe Grahe (4) | Seventh | 18 out |
| Sunday, July 12 |
| » Defeated Tigers (41-48), 5-4 | Tiger Stadium (3-3) | 35-52 | Won 3 |
| » W: Steve Frey (3-1) L: Mike Henneman (0-5) | Seventh | 18 out |
| Thursday, July 16 |
| » Defeated Yankees (42-46), 3-2 | Anaheim Stadium (18-20) | 36-52 | Won 4 |
| » W: Steve Frey (4-1) L: Melido Perez (8-8) | Sixth | 18 out |
| Friday, July 17 |
| » Defeated Yankees (42-47), 12-4 | Anaheim Stadium (19-20) | 37-52 | Won 5 |
| » W: Chuck Crim (3-2) L: Scott Sanderson (8-7) S: Joe Grahe (5) | Sixth | 18 out |
| Saturday, July 18 |
| » Defeated Yankees (42-48), 5-3 | Anaheim Stadium (20-20) | 38-52 | Won 6 |
| » W: Mark Langston (9-7) L: Scott Kamieniecki (2-7) S: Mark Eichhorn (2) | Sixth | 17 out |
| Sunday, July 19 |
| » Lost to Yankees (43-48), 8-3 | Anaheim Stadium (20-21) | 38-53 | |
| » W: Curt Young (2-2) L: Bert Blyleven (3-4) | Sixth | 18 out |
| Monday, July 20 |
| » Defeated Blue Jays (56-36), 5-3 | Anaheim Stadium (21-21) | 39-53 | |
| » W: Chuck Crim (4-2) L: Pat Hentgen (5-2) S: Joe Grahe (6) | Sixth | 17 out |
| » Major-league debuts: Tim Fortugno (Angels) |
| Tuesday, July 21 |
| » Lost to Blue Jays (57-36), 9-5 | Anaheim Stadium (21-22) | 39-54 | |
| » W: Jack Morris (12-3) L: Chuck Crim (4-3) S: Duane Ward (9) | Sixth | 17 out |
| Wednesday, July 22 |
| » Defeated Blue Jays (57-37), 5-4 | Anaheim Stadium (22-22) | 40-54 | |
| » W: Joe Grahe (3-3) L: Jimmy Key (6-8) | Sixth | 17 out |
| Thursday, July 23 |
| » Lost to Tigers (47-50), 5-2 | Anaheim Stadium (22-23) | 40-55 | |
| » W: Mark Leiter (7-4) L: Mark Langston (9-8) S: John Doherty (3) | Sixth | 17½ out |
| Friday, July 24 |
| » Defeated Tigers (47-51), 6-3 | Anaheim Stadium (23-23) | 41-55 | |
| » W: Bert Blyleven (4-4) L: Kevin Ritz (2-5) S: Joe Grahe (7) | Sixth | 17 out |
| Saturday, July 25 |
| » Defeated Tigers (47-52), 9-0 | Anaheim Stadium (24-23) | 42-55 | Won 2 |
| » W: Tim Fortugno (1-0) L: Walt Terrell (4-9) | Sixth | 17 out |
| Sunday, July 26 |
| » Defeated Tigers (47-53), 4-3 | Anaheim Stadium (25-23) | 43-55 | Won 3 |
| » W: Chuck Crim (5-3) L: John Doherty (2-2) S: Joe Grahe (8) | Fifth | 17 out |
| Monday, July 27 |
| » Defeated Mariners (39-62), 3-0 | Anaheim Stadium (26-23) | 44-55 | Won 4 |
| » W: Chuck Finley (3-9) L: Erik Hanson (8-13) S: Joe Grahe (9) | Fifth | 16 out |
| Tuesday, July 28 |
| » Lost to Mariners (40-62), 8-1 | Anaheim Stadium (26-24) | 44-56 | |
| » W: Dave Fleming (12-4) L: Mark Langston (9-9) | Fifth | 16 out |
| Wednesday, July 29 |
| » Lost to Mariners (41-62), 8-0 | Anaheim Stadium (26-25) | 44-57 | Lost 2 |
| » W: Brian Fisher (1-0) L: Bert Blyleven (4-5) | Fifth | 16 out |
| Thursday, July 30 |
| » Defeated Mariners (41-63), 6-5 | Anaheim Stadium (27-25) | 45-57 | |
| » W: Mark Eichhorn (2-4) L: Russ Swan (3-7) S: Joe Grahe (10) | Fifth | 15½ out |
| Friday, July 31 |
| » Defeated Rangers (54-51), 5-3 | Arlington Stadium (4-1) | 46-57 | Won 2 |
| » W: Chuck Crim (6-3) L: Bobby Witt (9-8) S: Joe Grahe (11) | Fifth | 15 out |
| Saturday, August 1 |
| » Defeated Rangers (54-52), 6-1 | Arlington Stadium (5-1) | 47-57 | Won 3 |
| » W: Chuck Finley (4-9) L: Nolan Ryan (5-4) | Fifth | 15 out |
| Sunday, August 2 |
| » Lost to Rangers (55-52), 5-1 | Arlington Stadium (5-2) | 47-58 | |
| » W: Kevin Brown (15-7) L: Mark Langston (9-10) | Fifth | 16 out |
| Tuesday, August 4 |
| » Defeated Royals (46-59), 5-1 | Royals Stadium (3-0) | 48-58 | |
| » W: Bert Blyleven (5-5) L: Kevin Appier (12-4) S: Chuck Crim (1) | Fourth | 15½ out |
| » Lost to Royals (47-59), 4-1 | Royals Stadium (3-1) | 48-59 | |
| » W: Luis Aquino (2-2) L: Tim Fortugno (1-1) | Fourth | 15½ out |
| Wednesday, August 5 |
| » Lost to Royals (48-59), 5-2 | Royals Stadium (3-2) | 48-60 | Lost 2 |
| » W: Tom Gordon (5-9) L: Julio Valera (5-9) S: Jeff Montgomery (26) | Sixth | 16½ out |
| Thursday, August 6 |
| » Lost to Royals (49-59), 7-6 | Royals Stadium (3-3) | 48-61 | Lost 3 |
| » W: Juan Berenguer (4-2) L: Chuck Crim (6-4) S: Jeff Montgomery (27) | Sixth | 17½ out |
| Friday, August 7 |
| » Defeated White Sox (55-52), 3-1 | Anaheim Stadium (28-25) | 49-61 | |
| » W: Mark Langston (10-10) L: Jack McDowell (15-6) S: Joe Grahe (12) | Sixth | 17½ out |
| Saturday, August 8 |
| » Lost to White Sox (56-52), 8-2 | Anaheim Stadium (28-26) | 49-62 | |
| » W: Roberto Hernandez (4-2) L: Steve Frey (4-2) | Sixth | 18½ out |
| Sunday, August 9 |
| » Lost to White Sox (57-52), 12-8 | Anaheim Stadium (28-27) | 49-63 | Lost 2 |
| » W: Donn Pall (5-2) L: Scott Bailes (3-1) | Sixth | 18½ out |
| Monday, August 10 |
| » Defeated Brewers (60-51), 4-1 | Anaheim Stadium (29-27) | 50-63 | |
| » W: Julio Valera (6-9) L: Bill Wegman (10-9) | Sixth | 18½ out |
| Tuesday, August 11 |
| » Defeated Brewers (60-52), 1-0 | Anaheim Stadium (30-27) | 51-63 | Won 2 |
| » W: Joe Grahe (4-3) L: Jaime Navarro (12-8) | Sixth | 17½ out |
| Wednesday, August 12 |
| » Defeated Brewers (60-53), 2-1 | Anaheim Stadium (31-27) | 52-63 | Won 3 |
| » W: Mark Langston (11-10) L: Bruce Ruffin (1-4) S: Joe Grahe (13) | Fifth | 17½ out |
| Thursday, August 13 |
| » Lost to Athletics (70-45), 4-1 | Oakland-Alameda County Stadium (1-3) | 52-64 | |
| » W: Mike Moore (12-9) L: Jim Abbott (4-12) | Fifth | 18½ out |
| » Major-league debuts: Damion Easley (Angels) |
| Friday, August 14 |
| » Defeated Athletics (70-46), 2-1 | Oakland-Alameda County Stadium (2-3) | 53-64 | |
| » W: Bert Blyleven (6-5) L: Dave Stewart (8-7) S: Joe Grahe (14) | Fifth | 17½ out |
| Saturday, August 15 |
| » Lost to Athletics (71-46), 9-5 | Oakland-Alameda County Stadium (2-4) | 53-65 | |
| » W: Jim Corsi (2-1) L: Chuck Crim (6-5) | Fifth | 18½ out |
| » Major-league debuts: Mike Raczka (Athletics) |
| Sunday, August 16 |
| » Lost to Athletics (72-46), 5-4 | Oakland-Alameda County Stadium (2-5) | 53-66 | Lost 2 |
| » W: Dennis Eckersley (6-0) L: Joe Grahe (4-4) | Sixth | 19½ out |
| Tuesday, August 18 |
| » Lost to Red Sox (55-64), 8-0 | Fenway Park (1-3) | 53-67 | Lost 3 |
| » W: Roger Clemens (15-7) L: Mark Langston (11-11) | Sixth | 19½ out |
| Wednesday, August 19 |
| » Defeated Red Sox (55-65), 3-2 | Fenway Park (2-3) | 54-67 | |
| » W: Jim Abbott (5-12) L: Jeff Reardon (2-2) S: Joe Grahe (15) | Sixth | 18½ out |
| Thursday, August 20 |
| » Defeated Red Sox (55-66), 2-0 | Fenway Park (3-3) | 55-67 | Won 2 |
| » W: Bert Blyleven (7-5) L: Danny Darwin (6-6) S: Joe Grahe (16) | Sixth | 18½ out |
| Friday, August 21 |
| » Defeated Yankees (55-67), 9-5 | Yankee Stadium (1-3) | 56-67 | Won 3 |
| » W: Mike Butcher (1-0) L: Shawn Hillegas (1-8) S: Tim Fortugno (1) | Sixth | 17½ out |
| » Major-league debuts: Tim Salmon (Angels) |
| Saturday, August 22 |
| » Lost to Yankees (56-67), 3-0 | Yankee Stadium (1-4) | 56-68 | |
| » W: Melido Perez (10-13) L: Chuck Finley (4-10) S: Steve Farr (19) | Sixth | 18½ out |
| Sunday, August 23 |
| » Defeated Yankees (56-68), 7-3 | Yankee Stadium (2-4) | 57-68 | |
| » W: Mike Butcher (2-0) L: Rich Monteleone (5-2) | Fifth | 18½ out |
| Monday, August 24 |
| » Defeated Orioles (68-57), 5-2 | Oriole Park at Camden Yards (2-2) | 58-68 | Won 2 |
| » W: Jim Abbott (6-12) L: Arthur Rhodes (4-4) S: Joe Grahe (17) | Fifth | 18½ out |
| Tuesday, August 25 |
| » Lost to Orioles (69-57), 9-1 | Oriole Park at Camden Yards (2-3) | 58-69 | |
| » W: Rick Sutcliffe (13-11) L: Bert Blyleven (7-6) | Fifth | 18½ out |
| Wednesday, August 26 |
| » Lost to Orioles (70-57), 6-4 | Oriole Park at Camden Yards (2-4) | 58-70 | Lost 2 |
| » W: Todd Frohwirth (4-2) L: Mike Butcher (2-1) S: Gregg Olson (29) | Fifth | 18½ out |
| Friday, August 28 |
| » Lost to Red Sox (59-69), 7-1 | Anaheim Stadium (31-28) | 58-71 | Lost 3 |
| » Manager: Buck Rodgers |
| » W: Roger Clemens (16-8) L: Chuck Finley (4-11) | Fifth | 19½ out |
| Saturday, August 29 |
| » Defeated Red Sox (59-70), 7-2 | Anaheim Stadium (32-28) | 59-71 | |
| » W: Mark Langston (12-11) L: John Dopson (6-7) | Fifth | 19½ out |
| Sunday, August 30 |
| » Lost to Red Sox (60-70), 4-2 | Anaheim Stadium (32-29) | 59-72 | |
| » W: Danny Darwin (7-6) L: Mike Butcher (2-2) S: Greg Harris (3) | Sixth | 20½ out |
| Monday, August 31 |
| » Lost to Indians (60-71), 4-3 | Anaheim Stadium (32-30) | 59-73 | Lost 2 |
| » W: Rod Nichols (3-3) L: Bert Blyleven (7-7) S: Eric Plunk (3) | Sixth | 20½ out |
| Tuesday, September 1 |
| » Defeated Indians (60-72), 7-6 | Anaheim Stadium (33-30) | 60-73 | |
| » W: Chuck Crim (7-5) L: Eric Plunk (5-3) S: Joe Grahe (18) | Sixth | 19½ out |
| Wednesday, September 2 |
| » Defeated Indians (60-73), 3-2 | Anaheim Stadium (34-30) | 61-73 | Won 2 |
| » W: Scott Lewis (2-0) L: Derek Lilliquist (5-3) | Sixth | 18½ out |
| Friday, September 4 |
| » Lost to Orioles (76-58), 8-7 | Anaheim Stadium (34-31) | 61-74 | |
| » W: Rick Sutcliffe (15-11) L: Mark Langston (12-12) S: Todd Frohwirth (4) | Fifth | 18½ out |
| Saturday, September 5 |
| » Lost to Orioles (77-58), 4-1 | Anaheim Stadium (34-32) | 61-75 | Lost 2 |
| » W: Mike Mussina (14-5) L: Jim Abbott (6-13) S: Gregg Olson (32) | Fifth | 18½ out |
| Sunday, September 6 |
| » Defeated Orioles (77-59), 5-2 | Anaheim Stadium (35-32) | 62-75 | |
| » W: Bert Blyleven (8-7) L: Craig Lefferts (13-10) S: Joe Grahe (19) | Fifth | 18½ out |
| Monday, September 7 |
| » Defeated Athletics (80-57), 3-2 | Anaheim Stadium (36-32) | 63-75 | Won 2 |
| » W: Julio Valera (7-9) L: Mike Moore (13-11) S: Joe Grahe (20) | Fifth | 17½ out |
| Tuesday, September 8 |
| » Lost to Athletics (81-57), 14-2 | Anaheim Stadium (36-33) | 63-76 | |
| » W: Kelly Downs (5-7) L: Chuck Finley (4-12) | Fifth | 18½ out |
| » Major-league debuts: Hilly Hathaway and Reggie Williams (Angels) |
| Wednesday, September 9 |
| » Lost to Athletics (82-57), 3-0 | Anaheim Stadium (36-34) | 63-77 | Lost 2 |
| » W: Dave Stewart (11-9) L: Mark Langston (12-13) S: Dennis Eckersley (43) | Fifth | 19½ out |
| Friday, September 11 |
| » Defeated Twins (78-63), 8-0 | Hubert H. Humphrey Metrodome (1-3) | 64-77 | |
| » W: Jim Abbott (7-13) L: John Smiley (14-8) | Fifth | 20 out |
| » Major-league debuts: Derek Parks (Twins) |
| Saturday, September 12 |
| » Lost to Twins (79-63), 7-2 | Hubert H. Humphrey Metrodome (1-4) | 64-78 | |
| » W: Mike Trombley (1-1) L: Bert Blyleven (8-8) S: Mark Guthrie (5) | Fifth | 21 out |
| Sunday, September 13 |
| » Lost to Twins (80-63), 6-2 | Hubert H. Humphrey Metrodome (1-5) | 64-79 | Lost 2 |
| » W: Scott Erickson (12-10) L: Julio Valera (7-10) | Fifth | 22 out |
| Tuesday, September 15 |
| » Defeated Mariners (56-89), 9-0 | Kingdome (3-2) | 65-79 | |
| » W: Chuck Finley (5-12) L: Dave Fleming (15-9) | Fifth | 22½ out |
| Wednesday, September 16 |
| » Defeated Mariners (56-90), 2-1 | Kingdome (4-2) | 66-79 | Won 2 |
| » W: Joe Grahe (5-4) L: Calvin Jones (3-5) S: Steve Frey (2) | Fifth | 22½ out |
| Thursday, September 17 |
| » Lost to Twins (81-66), 2-1 | Anaheim Stadium (36-35) | 66-80 | |
| » W: Mike Trombley (2-1) L: Jim Abbott (7-14) S: Rick Aguilera (38) | Fifth | 23 out |
| Friday, September 18 |
| » Lost to Twins (82-66), 4-1 | Anaheim Stadium (36-36) | 66-81 | Lost 2 |
| » W: Scott Erickson (13-10) L: Bert Blyleven (8-9) S: Rick Aguilera (39) | Fifth | 24 out |
| Saturday, September 19 |
| » Defeated Twins (82-67), 5-1 | Anaheim Stadium (37-36) | 67-81 | |
| » W: Julio Valera (8-10) L: Kevin Tapani (15-11) | Fifth | 23 out |
| Sunday, September 20 |
| » Lost to Twins (83-67), 7-5 | Anaheim Stadium (37-37) | 67-82 | |
| » W: Rick Aguilera (2-6) L: Joe Grahe (5-5) | Fifth | 24 out |
| Tuesday, September 22 |
| » Lost to Brewers (84-67), 3-2 | County Stadium (0-4) | 67-83 | Lost 2 |
| » W: Dan Plesac (5-4) L: Mark Langston (12-14) S: Darren Holmes (5) | Fifth | 24½ out |
| Wednesday, September 23 |
| » Lost to Brewers (85-67), 3-0 | County Stadium (0-5) | 67-84 | Lost 3 |
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