| Sunday, January 6 |
| Former Oriole Alan Wiggins dies in Los Angeles, CA at the age of 33. |
| Friday, January 25 |
| Former Oriole Hoot Evers dies in Houston, TX at the age of 70. |
| Saturday, March 9 |
| Former Oriole Jim Hardin dies in Key West, FL at the age of 48. |
| Monday, April 8 |
| » Lost to White Sox (1-0), 9-1 | Memorial Stadium (0-1) | 0-1 | |
| » W: Jack McDowell (1-0) L: Jeff Ballard (0-1) | Second | 1 out |
| Wednesday, April 10 |
| » Lost to White Sox (2-0), 2-0 | Memorial Stadium (0-2) | 0-2 | Lost 2 |
| » W: Greg Hibbard (1-0) L: Jose Mesa (0-1) S: Bobby Thigpen (1) | Fifth | 2 out |
| Friday, April 12 |
| » Defeated Rangers (0-3), 3-0 | Arlington Stadium (1-0) | 1-2 | |
| » W: Dave Johnson (1-0) L: Bobby Witt (0-1) S: Gregg Olson (1) | Third | 2 out |
| Saturday, April 13 |
| » Defeated Rangers (0-4), 11-4 | Arlington Stadium (2-0) | 2-2 | Won 2 |
| » W: Jeff Ballard (1-1) L: Kenny Rogers (0-1) | Third | 1 out |
| Sunday, April 14 |
| » Lost to Rangers (1-4), 15-3 | Arlington Stadium (2-1) | 2-3 | |
| » W: Nolan Ryan (1-1) L: Jeff Robinson (0-1) | Third | 2 out |
| Monday, April 15 |
| » Defeated Brewers (3-4), 7-2 | County Stadium (1-0) | 3-3 | |
| » W: Jose Mesa (1-1) L: Chris Bosio (1-1) S: Mark Williamson (1) | Third | 2 out |
| Wednesday, April 17 |
| » Lost to Brewers (4-4), 7-3 | County Stadium (1-1) | 3-4 | |
| » W: Jaime Navarro (1-0) L: Dave Johnson (1-1) S: Mark Lee (1) | Fourth | 1½ out |
| Thursday, April 18 |
| » Lost to Brewers (5-4), 4-3 | County Stadium (1-2) | 3-5 | Lost 2 |
| » W: Edwin Nunez (1-0) L: Jose Bautista (0-1) | Fifth | 2 out |
| Friday, April 19 |
| » Defeated Rangers (3-5), 5-0 | Memorial Stadium (1-2) | 4-5 | |
| » W: Jeff Robinson (1-1) L: Kenny Rogers (0-2) | Fourth | 2 out |
| Saturday, April 20 |
| » Lost to Rangers (4-5), 1-0 | Memorial Stadium (1-3) | 4-6 | |
| » W: Nolan Ryan (2-1) L: Jose Mesa (1-2) S: Jeff Russell (2) | Fifth | 3 out |
| Monday, April 22 |
| » Lost to White Sox (8-3), 8-7 | Comiskey Park II (0-1) | 4-7 | Lost 2 |
| » W: Alex Fernandez (2-1) L: Ben McDonald (0-1) S: Bobby Thigpen (5) | Fifth | 2½ out |
| Tuesday, April 23 |
| » Lost to White Sox (9-3), 10-4 | Comiskey Park II (0-2) | 4-8 | Lost 3 |
| » W: Jack McDowell (3-1) L: Dave Johnson (1-2) | Seventh | 3½ out |
| Wednesday, April 24 |
| » Defeated White Sox (9-4), 5-1 | Comiskey Park II (1-2) | 5-8 | |
| » W: Jeff Ballard (2-1) L: Charlie Hough (0-1) | Fifth | 2½ out |
| Friday, April 26 |
| » Lost to Brewers (8-8), 5-4 | Memorial Stadium (1-4) | 5-9 | |
| » W: Darren Holmes (1-0) L: Jose Mesa (1-3) S: Edwin Nunez (2) | Sixth | 4 out |
| Saturday, April 27 |
| » Lost to Brewers (9-8), 5-2 | Memorial Stadium (1-5) | 5-10 | Lost 2 |
| » W: Don August (1-2) L: Jeff Robinson (1-2) | Sixth | 4 out |
| Sunday, April 28 |
| » Defeated Brewers (9-9), 5-4 | Memorial Stadium (2-5) | 6-10 | |
| » W: Bob Milacki (1-0) L: Darren Holmes (1-1) S: Gregg Olson (2) | Sixth | 4 out |
| Monday, April 29 |
| » Lost to Mariners (9-11), 10-1 | Memorial Stadium (2-6) | 6-11 | |
| » W: Rich DeLucia (2-2) L: Dave Johnson (1-3) | Sixth | 4½ out |
| Tuesday, April 30 |
| » Lost to Mariners (10-11), 6-3 | Memorial Stadium (2-7) | 6-12 | Lost 2 |
| » W: Erik Hanson (2-1) L: Jeff Ballard (2-2) S: Russ Swan (2) | Sixth | 5 out |
| Wednesday, May 1 |
| » Defeated Mariners (10-12), 2-1 | Memorial Stadium (3-7) | 7-12 | |
| » W: Jose Mesa (2-3) L: Randy Johnson (2-3) S: Gregg Olson (3) | Fifth | 4 out |
| Friday, May 3 |
| » Defeated Angels (10-12), 2-0 | Anaheim Stadium (1-0) | 8-12 | Won 2 |
| » W: Ben McDonald (1-1) L: Kirk McCaskill (2-3) S: Gregg Olson (4) | Sixth | 4 out |
| Saturday, May 4 |
| » Lost to Angels (11-12), 6-3 | Anaheim Stadium (1-1) | 8-13 | |
| » W: Mark Langston (2-1) L: Jeff Robinson (1-3) S: Bryan Harvey (5) | Sixth | 5 out |
| Sunday, May 5 |
| » Lost to Angels (12-12), 6-4 | Anaheim Stadium (1-2) | 8-14 | Lost 2 |
| » W: Jim Abbott (1-4) L: Jeff Ballard (2-3) S: Bryan Harvey (6) | Sixth | 6 out |
| Monday, May 6 |
| » Defeated Angels (12-13), 7-0 | Anaheim Stadium (2-2) | 9-14 | |
| » W: Jose Mesa (3-3) L: Scott Lewis (1-2) | Sixth | 5½ out |
| Tuesday, May 7 |
| » Lost to Athletics (16-9), 11-3 | Oakland-Alameda County Stadium (0-1) | 9-15 | |
| » W: Mike Moore (5-0) L: Ben McDonald (1-2) | Sixth | 5½ out |
| Wednesday, May 8 |
| » Lost to Athletics (17-9), 9-3 | Oakland-Alameda County Stadium (0-2) | 9-16 | Lost 2 |
| » W: Curt Young (1-0) L: Mike Flanagan (0-1) | Sixth | 6½ out |
| Friday, May 10 |
| » Lost to Mariners (16-13), 3-1 | Kingdome (0-1) | 9-17 | Lost 3 |
| » W: Rich DeLucia (3-2) L: Jeff Ballard (2-4) S: Mike Jackson (3) | Seventh | 8 out |
| Saturday, May 11 |
| » Defeated Mariners (16-14), 11-5 | Kingdome (1-1) | 10-17 | |
| » W: Jose Mesa (4-3) L: Bill Krueger (1-1) | Sixth | 8 out |
| Sunday, May 12 |
| » Lost to Mariners (17-14), 5-4 | Kingdome (1-2) | 10-18 | |
| » W: Mike Jackson (3-2) L: Gregg Olson (0-1) | Seventh | 8 out |
| Tuesday, May 14 |
| » Defeated Athletics (18-13), 6-1 | Memorial Stadium (4-7) | 11-18 | |
| » W: Jeff Robinson (2-3) L: Joe Slusarski (1-1) | Seventh | 7½ out |
| Wednesday, May 15 |
| » Lost to Athletics (19-13), 6-3 | Memorial Stadium (4-8) | 11-19 | |
| » W: Bob Welch (4-2) L: Jeff Ballard (2-5) S: Dennis Eckersley (9) | Seventh | 8½ out |
| Thursday, May 16 |
| » Lost to Athletics (20-13), 11-5 | Memorial Stadium (4-9) | 11-20 | Lost 2 |
| » W: Joe Klink (2-2) L: Jose Mesa (4-4) | Seventh | 9 out |
| Friday, May 17 |
| » Defeated Angels (18-17), 5-1 | Memorial Stadium (5-9) | 12-20 | |
| » W: Ben McDonald (2-2) L: Scott Lewis (1-4) | Fifth | 8 out |
| Saturday, May 18 |
| » Lost to Angels (19-17), 4-2 | Memorial Stadium (5-10) | 12-21 | |
| » W: Chuck Finley (7-1) L: Mark Williamson (0-1) S: Bryan Harvey (9) | Fifth | 8 out |
| Sunday, May 19 |
| » Lost to Angels (20-17), 10-2 | Memorial Stadium (5-11) | 12-22 | Lost 2 |
| » W: Kirk McCaskill (3-5) L: Jeff Ballard (2-6) | Sixth | 8 out |
| Monday, May 20 |
| » Lost to Tigers (18-18), 11-5 | Tiger Stadium (0-1) | 12-23 | Lost 3 |
| » W: Jerry Don Gleaton (2-1) L: Bob Milacki (1-1) | Seventh | 9 out |
| Tuesday, May 21 |
| » Defeated Tigers (18-19), 5-4 | Tiger Stadium (1-1) | 13-23 | |
| » W: Mike Flanagan (1-1) L: Paul Gibson (2-2) S: Gregg Olson (5) | Sixth | 9 out |
| Wednesday, May 22 |
| » Lost to Tigers (19-19), 9-5 | Tiger Stadium (1-2) | 13-24 | |
| » W: Bill Gullickson (5-2) L: Ben McDonald (2-3) | Seventh | 10 out |
| Friday, May 24 |
| » Lost to Yankees (15-23), 7-1 | Memorial Stadium (5-12) | 13-25 | Lost 2 |
| » Manager: Johnny Oates |
| » W: Scott Sanderson (5-2) L: Jeff Robinson (2-4) | Seventh | 10½ out |
| Saturday, May 25 |
| » Lost to Yankees (16-23), 6-5 | Memorial Stadium (5-13) | 13-26 | Lost 3 |
| » W: Steve Farr (2-1) L: Mike Flanagan (1-2) S: Lee Guetterman (3) | Seventh | 10½ out |
| Sunday, May 26 |
| » Lost to Yankees (17-23), 2-1 | Memorial Stadium (5-14) | 13-27 | Lost 4 |
| » W: John Habyan (2-1) L: Mike Flanagan (1-3) S: Greg Cadaret (1) | Seventh | 10½ out |
| Monday, May 27 |
| » Lost to Indians (16-25), 3-2 | Memorial Stadium (5-15) | 13-28 | Lost 5 |
| » W: Tom Candiotti (6-2) L: Bob Milacki (1-2) S: Shawn Hillegas (2) | Seventh | 10½ out |
| Tuesday, May 28 |
| » Defeated Indians (16-26), 5-2 | Memorial Stadium (6-15) | 14-28 | |
| » W: Roy Smith (1-0) L: Charles Nagy (1-5) S: Gregg Olson (6) | Seventh | 10½ out |
| Wednesday, May 29 |
| » Defeated Indians (16-27), 2-1 | Memorial Stadium (7-15) | 15-28 | Won 2 |
| » W: Jeff Robinson (3-4) L: Mike Walker (0-1) S: Gregg Olson (7) | Seventh | 9½ out |
| Thursday, May 30 |
| » Defeated Red Sox (25-20), 9-3 | Fenway Park (1-0) | 16-28 | Won 3 |
| » W: Jeff Ballard (3-6) L: Matt Young (3-3) S: Mike Flanagan (1) | Seventh | 8½ out |
| Friday, May 31 |
| » Lost to Red Sox (26-20), 7-2 | Fenway Park (1-1) | 16-29 | |
| » W: Mike Gardiner (1-0) L: Jose Mesa (4-5) | Seventh | 9½ out |
| Saturday, June 1 |
| » Defeated Red Sox (26-21), 3-1 | Fenway Park (2-1) | 17-29 | |
| » W: Kevin Hickey (1-0) L: Danny Darwin (2-2) S: Gregg Olson (8) | Sixth | 8½ out |
| Sunday, June 2 |
| » Defeated Red Sox (26-22), 5-1 | Fenway Park (3-1) | 18-29 | Won 2 |
| » W: Roy Smith (2-0) L: Roger Clemens (7-3) S: Mark Williamson (2) | Sixth | 7½ out |
| Monday, June 3 |
| » Lost to Twins (26-25), 3-2 | Hubert H. Humphrey Metrodome (0-1) | 18-30 | |
| » W: Jack Morris (6-5) L: Jeff Robinson (3-5) S: Rick Aguilera (12) | Seventh | 8½ out |
| Tuesday, June 4 |
| » Lost to Twins (27-25), 4-3 | Hubert H. Humphrey Metrodome (0-2) | 18-31 | Lost 2 |
| » W: Carl Willis (2-1) L: Gregg Olson (0-2) | Seventh | 8½ out |
| Wednesday, June 5 |
| » Lost to Twins (28-25), 4-3 | Hubert H. Humphrey Metrodome (0-3) | 18-32 | Lost 3 |
| » W: Kevin Tapani (3-6) L: Jose Mesa (4-6) S: Rick Aguilera (13) | Seventh | 9½ out |
| Thursday, June 6 |
| » Defeated Blue Jays (29-25), 6-4 | Memorial Stadium (8-15) | 19-32 | |
| » W: Bob Milacki (2-2) L: Mike Timlin (4-3) S: Gregg Olson (9) | Seventh | 8½ out |
| Friday, June 7 |
| » Defeated Blue Jays (29-26), 6-4 | Memorial Stadium (9-15) | 20-32 | Won 2 |
| » W: Roy Smith (3-0) L: Juan Guzman (0-1) S: Gregg Olson (10) | Seventh | 7½ out |
| » Major-league debuts: Juan Guzman (Blue Jays) |
| Saturday, June 8 |
| » Lost to Blue Jays (30-26), 8-4 | Memorial Stadium (9-16) | 20-33 | |
| » W: Jimmy Key (9-2) L: Paul Kilgus (0-1) | Seventh | 8½ out |
| Sunday, June 9 |
| » Lost to Blue Jays (31-26), 3-2 | Memorial Stadium (9-17) | 20-34 | Lost 2 |
| » W: Todd Stottlemyre (6-2) L: Jeff Ballard (3-7) S: Tom Henke (8) | Seventh | 9½ out |
| Tuesday, June 11 |
| » Lost to Royals (25-30), 11-0 | Memorial Stadium (9-18) | 20-35 | Lost 3 |
| » W: Mark Gubicza (2-3) L: Jose Mesa (4-7) S: Steve Crawford (1) | Seventh | 9½ out |
| Wednesday, June 12 |
| » Lost to Royals (26-30), 9-8 | Memorial Stadium (9-19) | 20-36 | Lost 4 |
| » W: Mark Davis (2-1) L: Mark Williamson (0-2) S: Jeff Montgomery (12) | Seventh | 10½ out |
| Thursday, June 13 |
| » Lost to Royals (27-30), 6-4 | Memorial Stadium (9-20) | 20-37 | Lost 5 |
| » W: Mark Davis (3-1) L: Paul Kilgus (0-2) S: Jeff Montgomery (13) | Seventh | 11½ out |
| Friday, June 14 |
| » Lost to Blue Jays (34-27), 9-1 | Skydome (0-1) | 20-38 | Lost 6 |
| » W: Todd Stottlemyre (7-2) L: Jeff Robinson (3-6) | Seventh | 12½ out |
| Saturday, June 15 |
| » Defeated Blue Jays (34-28), 8-4 | Skydome (1-1) | 21-38 | |
| » W: Jeff Ballard (4-7) L: Juan Guzman (0-2) S: Mark Williamson (3) | Seventh | 11½ out |
| Sunday, June 16 |
| » Defeated Blue Jays (34-29), 13-8 | Skydome (2-1) | 22-38 | Won 2 |
| » W: Todd Frohwirth (1-0) L: Duane Ward (0-3) | Sixth | 11 out |
| Monday, June 17 |
| » Defeated Twins (38-26), 6-5 | Memorial Stadium (10-20) | 23-38 | Won 3 |
| » W: Mark Williamson (1-2) L: Rick Aguilera (2-3) | Sixth | 10 out |
| Tuesday, June 18 |
| » Lost to Twins (39-26), 9-2 | Memorial Stadium (10-21) | 23-39 | |
| » W: Scott Erickson (11-2) L: Roy Smith (3-1) S: Carl Willis (1) | Sixth | 10 out |
| Wednesday, June 19 |
| » Lost to Twins (40-26), 8-4 | Memorial Stadium (10-22) | 23-40 | Lost 2 |
| » W: Jack Morris (9-5) L: Gregg Olson (0-3) | Seventh | 10 out |
| Thursday, June 20 |
| » Lost to Royals (32-32), 3-2 | Royals Stadium (0-1) | 23-41 | Lost 3 |
| » W: Steve Crawford (2-0) L: Todd Frohwirth (1-1) | Seventh | 11 out |
| Friday, June 21 |
| » Major-league debuts: Chris Haney (Expos) |
| Saturday, June 22 |
| » Defeated Royals (32-33), 1-0 | Royals Stadium (1-1) | 24-41 | |
| » W: Bob Milacki (3-2) L: Tom Gordon (4-5) S: Gregg Olson (11) | Sixth | 11½ out |
| Sunday, June 23 |
| » Defeated Royals (32-34), 11-8 | Royals Stadium (2-1) | 25-41 | Won 2 |
| » W: Todd Frohwirth (2-1) L: Jeff Montgomery (1-4) S: Gregg Olson (12) | Sixth | 11 out |
| » Defeated Royals (32-35), 9-8 | Royals Stadium (3-1) | 26-41 | Won 3 |
| » W: Gregg Olson (1-3) L: Storm Davis (2-6) S: Paul Kilgus (1) | Sixth | 11 out |
| Tuesday, June 25 |
| » Defeated Indians (23-44), 5-3 | Cleveland Stadium (1-0) | 27-41 | Won 4 |
| » W: Mark Williamson (2-2) L: Doug Jones (1-6) S: Gregg Olson (13) | Sixth | 10½ out |
| Wednesday, June 26 |
| » Lost to Indians (24-44), 10-4 | Cleveland Stadium (1-1) | 27-42 | |
| » W: Greg Swindell (4-6) L: Jeff Ballard (4-8) S: Jeff Shaw (1) | Sixth | 11½ out |
| Thursday, June 27 |
| » Defeated Indians (24-45), 7-2 | Cleveland Stadium (2-1) | 28-42 | |
| » W: Bob Milacki (4-2) L: Jeff Mutis (0-3) S: Gregg Olson (14) | Sixth | 11½ out |
| Friday, June 28 |
| » Lost to Red Sox (37-34), 9-3 | Memorial Stadium (10-23) | 28-43 | |
| » W: Greg Harris (4-7) L: Jose Mesa (4-8) | Sixth | 11½ out |
| Saturday, June 29 |
| » Defeated Red Sox (37-35), 7-3 | Memorial Stadium (11-23) | 29-43 | |
| » W: Roy Smith (4-1) L: Danny Darwin (3-5) | Sixth | 11½ out |
| Sunday, June 30 |
| » Defeated Red Sox (37-36), 6-4 | Memorial Stadium (12-23) | 30-43 | Won 2 |
| » W: Mark Williamson (3-2) L: Joe Hesketh (2-1) S: Gregg Olson (15) | Sixth | 11½ out |
| Monday, July 1 |
| » Defeated Tigers (37-38), 10-2 | Memorial Stadium (13-23) | 31-43 | Won 3 |
| » W: Ben McDonald (3-3) L: Dan Gakeler (1-2) | Sixth | 11½ out |
| Tuesday, July 2 |
| » Lost to Tigers (38-38), 4-3 | Memorial Stadium (13-24) | 31-44 | |
| » W: Bill Gullickson (10-4) L: Jeff Ballard (4-9) S: Mike Henneman (12) | Sixth | 12½ out |
| Wednesday, July 3 |
| » Lost to Tigers (39-38), 8-2 | Memorial Stadium (13-25) | 31-45 | Lost 2 |
| » W: Frank Tanana (6-6) L: Bob Milacki (4-3) | Sixth | 13½ out |
| Thursday, July 4 |
| » Lost to Yankees (37-38), 3-2 | Yankee Stadium (0-1) | 31-46 | Lost 3 |
| » W: Eric Plunk (1-2) L: Roy Smith (4-2) S: Lee Guetterman (5) | Sixth | 13½ out |
| Friday, July 5 |
| » Defeated Yankees (37-39), 7-4 | Yankee Stadium (1-1) | 32-46 | |
| » W: Jeff Robinson (4-6) L: Tim Leary (4-8) S: Gregg Olson (16) | Sixth | 13½ out |
| » Major-league debuts: Chito Martinez (Orioles) |
| Saturday, July 6 |
| » Lost to Yankees (38-39), 13-5 | Yankee Stadium (1-2) | 32-47 | |
| » W: Eric Plunk (2-2) L: Todd Frohwirth (2-2) | Sixth | 14½ out |
| Sunday, July 7 |
| » Defeated Yankees (38-40), 5-3 | Yankee Stadium (2-2) | 33-47 | |
| » W: Jeff Ballard (5-9) L: Wade Taylor (4-3) S: Gregg Olson (17) | Sixth | 14½ out |
| » Major-league debuts: Bernie Williams (Yankees) |
| Thursday, July 11 |
| » Lost to Athletics (45-38), 8-1 | Oakland-Alameda County Stadium (0-3) | 33-48 | |
| » W: Dave Stewart (7-5) L: Jeff Robinson (4-7) | Sixth | 15½ out |
| Friday, July 12 |
| » Defeated Athletics (45-39), 6-3 | Oakland-Alameda County Stadium (1-3) | 34-48 | |
| » W: Ben McDonald (4-3) L: Curt Young (2-2) S: Gregg Olson (18) | Sixth | 15½ out |
| Saturday, July 13 |
| » Defeated Athletics (45-40), 2-0 | Oakland-Alameda County Stadium (2-3) | 35-48 | Won 2 |
| » W: Bob Milacki (5-3) L: Eric Show (0-1) S: Gregg Olson (19) | Sixth | 15½ out |
| Sunday, July 14 |
| » Lost to Athletics (46-40), 3-2 | Oakland-Alameda County Stadium (2-4) | 35-49 | |
| » W: Todd Burns (1-0) L: Gregg Olson (1-4) | Sixth | 15½ out |
| Monday, July 15 |
| » Defeated Angels (45-41), 2-1 | Anaheim Stadium (3-2) | 36-49 | |
| » W: Jeff Ballard (6-9) L: Bryan Harvey (1-3) S: Todd Frohwirth (1) | Sixth | 15½ out |
| Tuesday, July 16 |
| » Lost to Angels (46-41), 2-1 | Anaheim Stadium (3-3) | 36-50 | |
| » W: Mark Langston (13-3) L: Jeff Robinson (4-8) | Sixth | 15½ out |
| Wednesday, July 17 |
| » Lost to Royals (40-47), 9-8 | Royals Stadium (3-2) | 36-51 | Lost 2 |
| » W: Luis Aquino (3-2) L: Mark Williamson (3-3) | Sixth | 16 out |
| Thursday, July 18 |
| » Lost to Royals (41-47), 5-1 | Royals Stadium (3-3) | 36-52 | Lost 3 |
| » W: Bret Saberhagen (7-4) L: Bob Milacki (5-4) | Sixth | 17 out |
| » Major-league debuts: Tim Spehr (Royals) |
| Friday, July 19 |
| » Defeated Mariners (46-45), 4-1 | Memorial Stadium (14-25) | 37-52 | |
| » W: Roy Smith (5-2) L: Rich DeLucia (8-6) S: Gregg Olson (20) | Sixth | 17 out |
| Saturday, July 20 |
| » Lost to Mariners (47-45), 5-1 | Memorial Stadium (14-26) | 37-53 | |
| » W: Bill Krueger (7-3) L: Jeff Ballard (6-10) | Sixth | 17 out |
| Sunday, July 21 |
| » Lost to Mariners (48-45), 6-4 | Memorial Stadium (14-27) | 37-54 | Lost 2 |
| » W: Russ Swan (4-2) L: Jeff Robinson (4-9) S: Bill Swift (8) | Sixth | 17 out |
| Tuesday, July 23 |
| » Lost to Angels (48-44), 5-4 | Memorial Stadium (14-28) | 37-55 | Lost 3 |
| » W: Jim Abbott (8-7) L: Ben McDonald (4-4) S: Bryan Harvey (23) | Sixth | 17 out |
| Wednesday, July 24 |
| » Defeated Angels (48-45), 5-2 | Memorial Stadium (15-28) | 38-55 | |
| » W: Bob Milacki (6-4) L: Chuck Finley (13-5) S: Gregg Olson (21) | Sixth | 17 out |
| Thursday, July 25 |
| » Defeated Angels (48-46), 8-4 | Memorial Stadium (16-28) | 39-55 | Won 2 |
| » W: Todd Frohwirth (3-2) L: Kirk McCaskill (7-13) | Sixth | 16 out |
| Friday, July 26 |
| » Lost to Athletics (52-45), 12-9 | Memorial Stadium (16-29) | 39-56 | |
| » W: Joe Klink (7-2) L: Mark Williamson (3-4) S: Steve Chitren (4) | Sixth | 17 out |
| Saturday, July 27 |
| » Lost to Athletics (53-45), 9-1 | Memorial Stadium (16-30) | 39-57 | Lost 2 |
| » W: Joe Slusarski (3-4) L: Jeff Ballard (6-11) | Sixth | 17 out |
| Sunday, July 28 |
| » Lost to Athletics (54-45), 4-3 | Memorial Stadium (16-31) | 39-58 | Lost 3 |
| » W: Rick Honeycutt (2-2) L: Ben McDonald (4-5) S: Dennis Eckersley (25) | Sixth | 17 out |
| Monday, July 29 |
| » Lost to Mariners (53-47), 11-4 | Kingdome (1-3) | 39-59 | Lost 4 |
| » W: Erik Hanson (6-5) L: Bob Milacki (6-5) | Sixth | 17 out |
| Tuesday, July 30 |
| » Lost to Mariners (54-47), 8-2 | Kingdome (1-4) | 39-60 | Lost 5 |
| » W: Bill Krueger (9-3) L: Roy Smith (5-3) | Sixth | 17 out |
| » Major-league debuts: Stacy Jones (Orioles) |
| Wednesday, July 31 |
| » Defeated Mariners (54-48), 4-2 | Kingdome (2-4) | 40-60 | |
| » W: Mike Flanagan (2-3) L: Bill Swift (1-2) S: Gregg Olson (22) | Sixth | 17 out |
| Friday, August 2 |
| » Defeated White Sox (58-44), 3-0 | Comiskey Park II (2-2) | 41-60 | Won 2 |
| » W: Ben McDonald (5-5) L: Alex Fernandez (5-8) S: Gregg Olson (23) | Sixth | 16½ out |
| Saturday, August 3 |
| » Defeated White Sox (58-45), 6-3 | Comiskey Park II (3-2) | 42-60 | Won 3 |
| » W: Bob Milacki (7-5) L: Jack McDowell (13-6) S: Gregg Olson (24) | Sixth | 15½ out |
| Sunday, August 4 |
| » Lost to White Sox (59-45), 1-0 | Comiskey Park II (3-3) | 42-61 | |
| » W: Charlie Hough (7-6) L: Mike Mussina (0-1) | Sixth | 16½ out |
| » Major-league debuts: Mike Mussina (Orioles) |
| Monday, August 5 |
| » Lost to Brewers (45-60), 6-5 | Memorial Stadium (16-32) | 42-62 | Lost 2 |
| » W: Doug Henry (2-0) L: Mark Williamson (3-5) S: Edwin Nunez (4) | Sixth | 17 out |
| Tuesday, August 6 |
| » Defeated Brewers (45-61), 13-5 | Memorial Stadium (17-32) | 43-62 | |
| » W: Dave Johnson (2-3) L: Jim Hunter (0-5) | Sixth | 17 out |
| Wednesday, August 7 |
| » Lost to Brewers (46-61), 4-2 | Memorial Stadium (17-33) | 43-63 | |
| » W: Jaime Navarro (9-9) L: Ben McDonald (5-6) | Sixth | 18 out |
| Thursday, August 8 |
| » Lost to Brewers (47-61), 6-4 | Memorial Stadium (17-34) | 43-64 | Lost 2 |
| » W: Bill Wegman (7-6) L: Bob Milacki (7-6) S: Edwin Nunez (5) | Sixth | 18 out |
| Friday, August 9 |
| » Lost to White Sox (63-45), 7-4 | Memorial Stadium (17-35) | 43-65 | Lost 3 |
| » W: Brian Drahman (2-1) L: Mike Mussina (0-2) S: Bobby Thigpen (25) | Sixth | 18 out |
| Former Oriole Hank Majeski dies in Staten Island, NY at the age of 75. |
| Saturday, August 10 |
| » Lost to White Sox (64-45), 6-4 | Memorial Stadium (17-36) | 43-66 | Lost 4 |
| » W: Ramon Garcia (4-3) L: Mike Flanagan (2-4) S: Bobby Thigpen (26) | Sixth | 18 out |
| Sunday, August 11 |
| » Lost to White Sox (65-45), 7-0 | Memorial Stadium (17-37) | 43-67 | Lost 5 |
| » W: Wilson Alvarez (1-0) L: Dave Johnson (2-4) | Sixth | 18 out |
| Monday, August 12 |
| » Defeated White Sox (65-46), 5-4 | Memorial Stadium (18-37) | 44-67 | |
| » W: Gregg Olson (2-4) L: Donn Pall (5-2) | Sixth | 17 out |
| Tuesday, August 13 |
| » Defeated Rangers (57-52), 4-3 | Memorial Stadium (19-37) | 45-67 | Won 2 |
| » W: Dave Johnson (3-4) L: Kenny Rogers (8-8) | Sixth | 15½ out |
| » Defeated Rangers (57-53), 8-7 | Memorial Stadium (20-37) | 46-67 | Won 3 |
| » W: Todd Frohwirth (4-2) L: Jose Guzman (7-5) S: Gregg Olson (25) | Sixth | 15½ out |
| Wednesday, August 14 |
| » Defeated Rangers (57-54), 10-2 | Memorial Stadium (21-37) | 47-67 | Won 4 |
| » W: Mike Mussina (1-2) L: Gerald Alexander (5-3) | Sixth | 14½ out |
| Thursday, August 15 |
| » Defeated Rangers (57-55), 9-2 | Memorial Stadium (22-37) | 48-67 | Won 5 |
| » W: Jose Mesa (5-8) L: Oil Can Boyd (6-12) | Sixth | 14½ out |
| Friday, August 16 |
| » Lost to Brewers (53-63), 8-5 | County Stadium (1-3) | 48-68 | |
| » W: Don August (9-5) L: Roy Smith (5-4) | Sixth | 14½ out |
| Saturday, August 17 |
| » Lost to Brewers (54-63), 7-6 | County Stadium (1-4) | 48-69 | Lost 2 |
| » W: Jaime Navarro (11-9) L: Ben McDonald (5-7) S: Edwin Nunez (7) | Sixth | 15½ out |
| Sunday, August 18 |
| » Lost to Brewers (55-63), 2-1 | County Stadium (1-5) | 48-70 | Lost 3 |
| » W: Bill Wegman (8-6) L: Bob Milacki (7-7) S: Doug Henry (4) | Sixth | 16½ out |
| Monday, August 19 |
| » Lost to Rangers (61-56), 4-1 | Arlington Stadium (2-2) | 48-71 | Lost 4 |
| » W: Nolan Ryan (8-5) L: Mike Mussina (1-3) S: Terry Mathews (1) | Sixth | 17 out |
| Tuesday, August 20 |
| » Defeated Rangers (61-57), 8-6 | Arlington Stadium (3-2) | 49-71 | |
| » W: Dave Johnson (4-4) L: Wayne Rosenthal (1-2) S: Mike Flanagan (2) | Sixth | 17 out |
| Wednesday, August 21 |
| » Defeated Rangers (61-58), 4-3 | Arlington Stadium (4-2) | 50-71 | Won 2 |
| » W: Todd Frohwirth (5-2) L: Kevin Brown (8-10) S: Gregg Olson (26) | Sixth | 16 out |
| » Major-league debuts: Arthur Rhodes (Orioles) |
| Friday, August 23 |
| » Defeated Twins (74-50), 5-4 | Memorial Stadium (23-37) | 51-71 | Won 3 |
| » W: Gregg Olson (3-4) L: Carl Willis (7-3) | Sixth | 15½ out |
| Saturday, August 24 |
| » Lost to Twins (75-50), 5-2 | Memorial Stadium (23-38) | 51-72 | |
| » W: Steve Bedrosian (5-3) L: Mike Flanagan (2-5) S: Rick Aguilera (33) | Fifth | 15½ out |
| Sunday, August 25 |
| » Defeated Twins (75-51), 7-3 | Memorial Stadium (24-38) | 52-72 | |
| » W: Mike Mussina (2-3) L: Scott Erickson (16-6) S: Todd Frohwirth (2) | Fifth | 15½ out |
| Monday, August 26 |
| » Lost to Blue Jays (69-57), 5-2 | Memorial Stadium (24-39) | 52-73 | |
| » W: Jimmy Key (13-9) L: Dave Johnson (4-5) S: Tom Henke (30) | Fifth | 16½ out |
| Tuesday, August 27 |
| » Lost to Blue Jays (70-57), 6-1 | Memorial Stadium (24-40) | 52-74 | Lost 2 |
| » W: Juan Guzman (5-2) L: Arthur Rhodes (0-1) | Sixth | 17½ out |
| Wednesday, August 28 |
| » Lost to Blue Jays (71-57), 3-0 | Memorial Stadium (24-41) | 52-75 | Lost 3 |
| » W: Tom Candiotti (11-11) L: Ben McDonald (5-8) S: Tom Henke (31) | Sixth | 18½ out |
| Friday, August 30 |
| » Defeated Twins (77-53), 11-5 | Hubert H. Humphrey Metrodome (1-3) | 53-75 | |
| » W: Bob Milacki (8-7) L: Tom Edens (0-1) | Sixth | 18 out |
| Saturday, August 31 |
| » Lost to Twins (78-53), 5-2 | Hubert H. Humphrey Metrodome (1-4) | 53-76 | |
| » W: Kevin Tapani (13-7) L: Mike Mussina (2-4) S: Rick Aguilera (36) | Sixth | 19 out |
| Sunday, September 1 |
| » Lost to Twins (79-53), 14-3 | Hubert H. Humphrey Metrodome (1-5) | 53-77 | Lost 2 |
| » W: Jack Morris (16-10) L: Arthur Rhodes (0-2) | Sixth | 19 out |
| Monday, September 2 |
| » Lost to Blue Jays (74-59), 5-4 | Skydome (2-2) | 53-78 | Lost 3 |
| » W: Mike Timlin (10-6) L: Gregg Olson (3-5) | Sixth | 20 out |
| » Major-league debuts: Eddie Zosky (Blue Jays) |
| Tuesday, September 3 |
| » Defeated Blue Jays (74-60), 8-4 | Skydome (3-2) | 54-78 | |
| » W: Ben McDonald (6-8) L: David Wells (13-10) S: Mike Flanagan (3) | Sixth | 19 out |
| » Major-league debuts: Pat Hentgen (Blue Jays) |
| Wednesday, September 4 |
| » Lost to Blue Jays (75-60), 3-1 | Skydome (3-3) | 54-79 | |
| » W: Todd Stottlemyre (13-6) L: Bob Milacki (8-8) S: Duane Ward (18) | Sixth | 20 out |
| Friday, September 6 |
| » Defeated Royals (68-66), 6-2 | Memorial Stadium (25-41) | 55-79 | |
| » W: Jim Poole (1-0) L: Bret Saberhagen (10-8) | Sixth | 20½ out |
| Saturday, September 7 |
| » Lost to Royals (69-66), 7-4 | Memorial Stadium (25-42) | 55-80 | |
| » W: Luis Aquino (7-3) L: Jose Mesa (5-9) | Sixth | 21½ out |
| » Major-league debuts: Francisco De la Rosa (Orioles) Jorge Pedre (Royals) |
| Sunday, September 8 |
| » Lost to Royals (70-66), 3-2 | Memorial Stadium (25-43) | 55-81 | Lost 2 |
| » W: Joel Johnston (1-0) L: Todd Frohwirth (5-3) S: Jeff Montgomery (27) | Sixth | 22½ out |
| » Major-league debuts: Luis Mercedes (Orioles) |
| Monday, September 9 |
| » Defeated Yankees (60-76), 8-0 | Memorial Stadium (26-43) | 56-81 | |
| » W: Bob Milacki (9-8) L: Scott Sanderson (14-9) | Sixth | 22 out |
| Tuesday, September 10 |
| » Defeated Yankees (60-77), 6-3 | Memorial Stadium (27-43) | 57-81 | Won 2 |
| » W: Todd Frohwirth (6-3) L: Eric Plunk (2-4) | Sixth | 21 out |
| Wednesday, September 11 |
| » Defeated Yankees (60-78), 4-2 | Memorial Stadium (28-43) | 58-81 | Won 3 |
| » W: Mike Mussina (3-4) L: Wade Taylor (7-9) S: Gregg Olson (27) | Sixth | 20 out |
| » Major-league debuts: Jeff Tackett (Orioles) |
| Thursday, September 12 |
| » Lost to Indians (46-93), 6-5 | Memorial Stadium (28-44) | 58-82 | |
| » W: Charles Nagy (9-12) L: Jose Mesa (5-10) S: Steve Olin (11) | Sixth | 20½ out |
| » Major-league debuts: Wayne Kirby and Tom Kramer (Indians) |
| Friday, September 13 |
| » Defeated Indians (46-94), 5-4 | Memorial Stadium (29-44) | 59-82 | |
| » W: Gregg Olson (4-5) L: Jeff Shaw (0-5) | Sixth | 20½ out |
| Saturday, September 14 |
| » Lost to Indians (47-94), 6-5 | Memorial Stadium (29-45) | 59-83 | |
| » W: Eric Bell (1-0) L: Mike Flanagan (2-6) S: Steve Olin (12) | Sixth | 21½ out |
| Sunday, September 15 |
| » Defeated Indians (47-95), 4-3 | Memorial Stadium (30-45) | 60-83 | |
| » W: Mark Williamson (4-5) L: Willie Blair (2-3) S: Gregg Olson (28) | Sixth | 20½ out |
| Monday, September 16 |
| » Defeated Red Sox (77-67), 9-2 | Fenway Park (4-1) | 61-83 | Won 2 |
| » W: Mike Mussina (4-4) L: Tom Bolton (8-8) | Sixth | 19½ out |
| Tuesday, September 17 |
| » Lost to Red Sox (78-67), 4-3 | Fenway Park (4-2) | 61-84 | |
| » W: Kevin Morton (6-3) L: Jose Mesa (5-11) S: Jeff Reardon (40) | Sixth | 19½ out |
| » Major-league debuts: Wayne Housie (Red Sox) |
| Wednesday, |