| Monday, April 8 |
| » Major-league debuts: Mike Timlin (Blue Jays) |
| Tuesday, April 9 |
| » Defeated Twins (0-1), 7-2 | Oakland-Alameda County Stadium (1-0) | 1-0 | |
| » W: Dave Stewart (1-0) L: Jack Morris (0-1) | First | -- |
| » Major-league debuts: Dana Allison (Athletics) Chuck Knoblauch (Twins) |
| Wednesday, April 10 |
| » Lost to Twins (1-1), 4-1 | Oakland-Alameda County Stadium (1-1) | 1-1 | |
| » W: Allan Anderson (1-0) L: Bob Welch (0-1) S: Rick Aguilera (1) | Third | 1 out |
| Thursday, April 11 |
| » Defeated Twins (1-2), 3-0 | Oakland-Alameda County Stadium (2-1) | 2-1 | |
| » W: Joe Slusarski (1-0) L: Scott Erickson (0-1) S: Dennis Eckersley (1) | Third | 1 out |
| » Major-league debuts: Joe Slusarski (Athletics) |
| Friday, April 12 |
| » Defeated Mariners (0-4), 6-1 | Oakland-Alameda County Stadium (3-1) | 3-1 | Won 2 |
| » W: Mike Moore (1-0) L: Scott Bankhead (0-1) | Second | ½ out |
| Saturday, April 13 |
| » Defeated Mariners (0-5), 4-2 | Oakland-Alameda County Stadium (4-1) | 4-1 | Won 3 |
| » W: Kirk Dressendorfer (1-0) L: Rich DeLucia (0-1) S: Dennis Eckersley (2) | Second | ½ out |
| » Major-league debuts: Kirk Dressendorfer (Athletics) |
| Sunday, April 14 |
| » Defeated Mariners (0-6), 7-6 | Oakland-Alameda County Stadium (5-1) | 5-1 | Won 4 |
| » W: Dana Allison (1-0) L: Mike Jackson (0-1) | Second | 1 out |
| Monday, April 15 |
| » Defeated Angels (5-2), 5-2 | Anaheim Stadium (1-0) | 6-1 | Won 5 |
| » W: Bob Welch (1-1) L: Kirk McCaskill (1-1) S: Dennis Eckersley (3) | Second | 1 out |
| Tuesday, April 16 |
| » Defeated Angels (5-3), 8-5 | Anaheim Stadium (2-0) | 7-1 | Won 6 |
| » W: Steve Chitren (1-0) L: Scott Bailes (1-1) S: Dennis Eckersley (4) | Second | 1 out |
| Wednesday, April 17 |
| » Defeated Angels (5-4), 3-1 | Anaheim Stadium (3-0) | 8-1 | Won 7 |
| » W: Mike Moore (2-0) L: Jim Abbott (0-2) S: Joe Klink (1) | First | -- |
| Thursday, April 18 |
| » Lost to Angels (6-4), 7-1 | Anaheim Stadium (3-1) | 8-2 | |
| » W: Scott Lewis (1-0) L: Kirk Dressendorfer (1-1) | First | -- |
| » Major-league debuts: John Briscoe (Athletics) |
| Friday, April 19 |
| » Lost to Mariners (4-6), 11-7 | Kingdome (0-1) | 8-3 | Lost 2 |
| » W: Rich DeLucia (1-1) L: Dave Stewart (1-1) S: Rob Murphy (1) | Second | 1½ out |
| Saturday, April 20 |
| » Lost to Mariners (5-6), 3-2 | Kingdome (0-2) | 8-4 | Lost 3 |
| » W: Erik Hanson (1-1) L: Dennis Eckersley (0-1) | First | -- |
| Sunday, April 21 |
| » Lost to Mariners (6-6), 7-2 | Kingdome (0-3) | 8-5 | Lost 4 |
| » W: Randy Johnson (2-1) L: Dana Allison (1-1) | Second | 1½ out |
| Monday, April 22 |
| » Lost to Twins (4-9), 3-2 | Hubert H. Humphrey Metrodome (0-1) | 8-6 | Lost 5 |
| » W: Steve Bedrosian (1-0) L: Joe Klink (0-1) S: Rick Aguilera (3) | Second | 1½ out |
| Tuesday, April 23 |
| » Defeated Twins (4-10), 7-5 | Hubert H. Humphrey Metrodome (1-1) | 9-6 | |
| » W: Kirk Dressendorfer (2-1) L: Mark Guthrie (0-2) S: Dennis Eckersley (5) | Second | 1½ out |
| Wednesday, April 24 |
| » Lost to Twins (5-10), 7-4 | Hubert H. Humphrey Metrodome (1-2) | 9-7 | |
| » W: Jack Morris (1-3) L: Dave Stewart (1-2) S: Rick Aguilera (4) | Second | 1½ out |
| Friday, April 26 |
| » Defeated Angels (9-8), 4-1 | Oakland-Alameda County Stadium (6-1) | 10-7 | |
| » W: Bob Welch (2-1) L: Kirk McCaskill (2-2) S: Dennis Eckersley (6) | Second | 1½ out |
| Saturday, April 27 |
| » Defeated Angels (9-9), 4-3 | Oakland-Alameda County Stadium (7-1) | 11-7 | Won 2 |
| » W: Mike Moore (3-0) L: Mark Langston (1-1) S: Dennis Eckersley (7) | Second | 1½ out |
| Sunday, April 28 |
| » Defeated Angels (9-10), 7-3 | Oakland-Alameda County Stadium (8-1) | 12-7 | Won 3 |
| » W: Dave Stewart (2-2) L: Jim Abbott (0-4) | Second | 1½ out |
| Tuesday, April 30 |
| » Defeated Yankees (6-11), 7-3 | Oakland-Alameda County Stadium (9-1) | 13-7 | Won 4 |
| » W: Bob Welch (3-1) L: Dave Eiland (1-1) | First | -- |
| Wednesday, May 1 |
| » Defeated Yankees (6-12), 7-4 | Oakland-Alameda County Stadium (10-1) | 14-7 | Won 5 |
| » W: Mike Moore (4-0) L: Tim Leary (2-1) S: Dennis Eckersley (8) | First | -- |
| Friday, May 3 |
| » Defeated Indians (8-11), 4-3 | Oakland-Alameda County Stadium (11-1) | 15-7 | Won 6 |
| » W: Joe Klink (1-1) L: Steve Olin (2-2) | First | -- |
| Saturday, May 4 |
| » Lost to Indians (9-11), 20-6 | Oakland-Alameda County Stadium (11-2) | 15-8 | |
| » W: Eric King (3-2) L: Kirk Dressendorfer (2-2) | First | -- |
| Sunday, May 5 |
| » Lost to Indians (10-11), 15-6 | Oakland-Alameda County Stadium (11-3) | 15-9 | Lost 2 |
| » W: Greg Swindell (1-3) L: Bob Welch (3-2) | First | -- |
| Monday, May 6 |
| » Major-league debuts: Rod Beck (Giants) |
| Tuesday, May 7 |
| » Defeated Orioles (9-15), 11-3 | Oakland-Alameda County Stadium (12-3) | 16-9 | |
| » W: Mike Moore (5-0) L: Ben McDonald (1-2) | First | -- |
| Wednesday, May 8 |
| » Defeated Orioles (9-16), 9-3 | Oakland-Alameda County Stadium (13-3) | 17-9 | Won 2 |
| » W: Curt Young (1-0) L: Mike Flanagan (0-1) | First | -- |
| Friday, May 10 |
| » Lost to Yankees (9-16), 5-3 | Yankee Stadium (0-1) | 17-10 | |
| » W: John Habyan (1-1) L: Joe Klink (1-2) S: Steve Farr (2) | First | -- |
| Saturday, May 11 |
| » Defeated Yankees (9-17), 10-2 | Yankee Stadium (1-1) | 18-10 | |
| » W: Kirk Dressendorfer (3-2) L: Dave Eiland (1-2) | First | -- |
| » Major-league debuts: Bruce Walton (Athletics) |
| Sunday, May 12 |
| » Lost to Yankees (10-17), 10-6 | Yankee Stadium (1-2) | 18-11 | |
| » W: Steve Farr (1-1) L: Mike Moore (5-1) | First | -- |
| Monday, May 13 |
| » Lost to Yankees (11-17), 6-3 | Yankee Stadium (1-3) | 18-12 | Lost 2 |
| » W: Scott Sanderson (4-1) L: Curt Young (1-1) S: Lee Guetterman (1) | First | -- |
| Tuesday, May 14 |
| » Lost to Orioles (11-18), 6-1 | Memorial Stadium (0-1) | 18-13 | Lost 3 |
| » W: Jeff Robinson (2-3) L: Joe Slusarski (1-1) | First | -- |
| Wednesday, May 15 |
| » Defeated Orioles (11-19), 6-3 | Memorial Stadium (1-1) | 19-13 | |
| » W: Bob Welch (4-2) L: Jeff Ballard (2-5) S: Dennis Eckersley (9) | First | -- |
| Thursday, May 16 |
| » Defeated Orioles (11-20), 11-5 | Memorial Stadium (2-1) | 20-13 | Won 2 |
| » W: Joe Klink (2-2) L: Jose Mesa (4-4) | First | -- |
| Friday, May 17 |
| » Lost to Indians (12-19), 11-6 | Cleveland Stadium (0-1) | 20-14 | |
| » W: Tom Candiotti (5-1) L: Mike Moore (5-2) | Second | ½ out |
| » Major-league debuts: Ever Magallanes (Indians) Catfish Hunter (Athletics) |
| Saturday, May 18 |
| » Defeated Indians (12-20), 3-0 | Cleveland Stadium (1-1) | 21-14 | |
| » W: Andy Hawkins (1-2) L: Charles Nagy (1-3) S: Dennis Eckersley (10) | Second | ½ out |
| » Major-league debuts: Eddie Taubensee (Indians) |
| Sunday, May 19 |
| » Defeated Indians (12-21), 9-4 | Cleveland Stadium (2-1) | 22-14 | Won 2 |
| » W: Curt Young (2-1) L: Rod Nichols (0-2) | First | -- |
| Monday, May 20 |
| » Lost to Blue Jays (23-16), 1-0 | Oakland-Alameda County Stadium (13-4) | 22-15 | |
| » W: David Wells (5-3) L: Bob Welch (4-3) S: Tom Henke (3) | Second | ½ out |
| Tuesday, May 21 |
| » Lost to Blue Jays (24-16), 11-7 | Oakland-Alameda County Stadium (13-5) | 22-16 | Lost 2 |
| » W: Jim Acker (1-1) L: Kirk Dressendorfer (3-3) S: Mike Timlin (2) | Second | ½ out |
| Wednesday, May 22 |
| » Defeated Blue Jays (24-17), 2-1 | Oakland-Alameda County Stadium (14-5) | 23-16 | |
| » W: Mike Moore (6-2) L: Dave Stieb (4-3) S: Dennis Eckersley (11) | First | -- |
| Thursday, May 23 |
| » Lost to White Sox (19-18), 11-1 | Oakland-Alameda County Stadium (14-6) | 23-17 | |
| » W: Greg Hibbard (3-2) L: Andy Hawkins (1-3) | Second | 2½ out |
| Friday, May 24 |
| » Defeated White Sox (19-19), 6-5 | Oakland-Alameda County Stadium (15-6) | 24-17 | |
| » W: Dennis Eckersley (1-1) L: Bobby Thigpen (2-1) | Second | 2½ out |
| Saturday, May 25 |
| » Defeated White Sox (19-20), 5-3 | Oakland-Alameda County Stadium (16-6) | 25-17 | Won 2 |
| » W: Joe Klink (3-2) L: Wayne Edwards (0-2) | Second | 2½ out |
| Sunday, May 26 |
| » Defeated White Sox (19-21), 6-2 | Oakland-Alameda County Stadium (17-6) | 26-17 | Won 3 |
| » W: Dave Stewart (3-2) L: Alex Fernandez (2-4) S: Joe Klink (2) | Second | 2½ out |
| Tuesday, May 28 |
| » Defeated Blue Jays (25-20), 8-4 | Skydome (1-0) | 27-17 | Won 4 |
| » W: Mike Moore (7-2) L: Jim Acker (1-2) S: Dennis Eckersley (12) | Second | 2 out |
| Wednesday, May 29 |
| » Lost to Blue Jays (26-20), 8-3 | Skydome (1-1) | 27-18 | |
| » W: Jimmy Key (7-2) L: Joe Slusarski (1-2) S: Tom Henke (5) | Second | 2 out |
| Thursday, May 30 |
| » Defeated Blue Jays (26-21), 8-6 | Skydome (2-1) | 28-18 | |
| » W: Joe Klink (4-2) L: Duane Ward (0-2) S: Dennis Eckersley (13) | First | -- |
| Friday, May 31 |
| » Lost to White Sox (21-23), 5-4 | Comiskey Park II (0-1) | 28-19 | |
| » W: Bobby Thigpen (3-1) L: Steve Chitren (1-1) | Second | 2 out |
| » Major-league debuts: Ramon Garcia (White Sox) |
| Saturday, June 1 |
| » Defeated White Sox (21-24), 7-4 | Comiskey Park II (1-1) | 29-19 | |
| » W: Joe Klink (5-2) L: Alex Fernandez (2-5) S: Dennis Eckersley (14) | First | -- |
| Sunday, June 2 |
| » Lost to White Sox (22-24), 4-3 | Comiskey Park II (1-2) | 29-20 | |
| » W: Charlie Hough (2-2) L: Mike Moore (7-3) S: Bobby Thigpen (10) | First | -- |
| Monday, June 3 |
| » Defeated White Sox (22-25), 5-3 | Comiskey Park II (2-2) | 30-20 | |
| » W: Joe Slusarski (2-2) L: Greg Hibbard (3-4) S: Dennis Eckersley (15) | First | -- |
| Tuesday, June 4 |
| » Defeated Brewers (23-26), 4-3 | Oakland-Alameda County Stadium (18-6) | 31-20 | Won 2 |
| » W: Bob Welch (5-3) L: Jaime Navarro (5-3) S: Dennis Eckersley (16) | First | -- |
| Wednesday, June 5 |
| » Defeated Brewers (23-27), 6-4 | Oakland-Alameda County Stadium (19-6) | 32-20 | Won 3 |
| » W: Dave Stewart (4-2) L: Chris Bosio (4-6) S: Steve Chitren (1) | First | -- |
| Thursday, June 6 |
| » Defeated Brewers (23-28), 9-8 | Oakland-Alameda County Stadium (20-6) | 33-20 | Won 4 |
| » W: Bruce Walton (1-0) L: Chuck Crim (3-4) S: Dennis Eckersley (17) | First | -- |
| Friday, June 7 |
| » Lost to Red Sox (27-25), 3-1 | Oakland-Alameda County Stadium (20-7) | 33-21 | |
| » W: Greg Harris (2-5) L: Mike Moore (7-4) S: Jeff Reardon (15) | First | -- |
| Saturday, June 8 |
| » Lost to Red Sox (28-25), 8-1 | Oakland-Alameda County Stadium (20-8) | 33-22 | Lost 2 |
| » W: Roger Clemens (8-3) L: Joe Slusarski (2-3) | First | -- |
| » Major-league debuts: Johnny Guzman (Athletics) |
| Sunday, June 9 |
| » Defeated Red Sox (28-26), 8-0 | Oakland-Alameda County Stadium (21-8) | 34-22 | |
| » W: Bob Welch (6-3) L: Tom Bolton (5-4) | First | -- |
| Monday, June 10 |
| » Defeated Tigers (27-29), 12-6 | Oakland-Alameda County Stadium (22-8) | 35-22 | Won 2 |
| » W: Johnny Guzman (1-0) L: Mike Henneman (5-2) | First | -- |
| Tuesday, June 11 |
| » Lost to Tigers (28-29), 5-1 | Oakland-Alameda County Stadium (22-9) | 35-23 | |
| » W: Bill Gullickson (7-3) L: Andy Hawkins (1-4) S: Mike Henneman (9) | First | -- |
| Wednesday, June 12 |
| » Defeated Tigers (28-30), 3-1 | Oakland-Alameda County Stadium (23-9) | 36-23 | |
| » W: Mike Moore (8-4) L: Frank Tanana (3-6) S: Dennis Eckersley (18) | First | -- |
| Saturday, June 15 |
| » Lost to Brewers (26-32), 6-4 | County Stadium (0-1) | 36-24 | |
| » W: Jaime Navarro (6-4) L: Dave Stewart (4-3) S: Dan Plesac (2) | First | -- |
| » Defeated Brewers (26-33), 7-3 | County Stadium (1-1) | 37-24 | |
| » W: Andy Hawkins (2-4) L: Kevin Brown (2-4) S: Steve Chitren (2) | First | -- |
| Sunday, June 16 |
| » Lost to Brewers (27-33), 11-7 | County Stadium (1-2) | 37-25 | |
| » W: Chuck Crim (4-4) L: Gene Nelson (0-1) | Second | ½ out |
| Monday, June 17 |
| » Lost to Brewers (28-33), 5-0 | County Stadium (1-3) | 37-26 | Lost 2 |
| » W: Don August (5-2) L: Mike Moore (8-5) | Second | ½ out |
| Tuesday, June 18 |
| » Lost to Tigers (31-32), 2-0 | Tiger Stadium (0-1) | 37-27 | Lost 3 |
| » W: Frank Tanana (4-6) L: Bob Welch (6-4) S: Mike Henneman (10) | Second | 1½ out |
| Wednesday, June 19 |
| » Defeated Tigers (31-33), 5-4 | Tiger Stadium (1-1) | 38-27 | |
| » W: Gene Nelson (1-1) L: Walt Terrell (3-7) S: Dennis Eckersley (19) | Second | 1½ out |
| Thursday, June 20 |
| » Lost to Red Sox (34-30), 8-7 | Fenway Park (0-1) | 38-28 | |
| » W: Jeff Gray (2-3) L: Steve Chitren (1-2) S: Jeff Reardon (18) | Second | 2 out |
| Friday, June 21 |
| » Lost to Red Sox (35-30), 3-2 | Fenway Park (0-2) | 38-29 | Lost 2 |
| » W: Tom Bolton (7-4) L: Mike Moore (8-6) S: Jeff Reardon (19) | Second | 3 out |
| Saturday, June 22 |
| » Lost to Red Sox (36-30), 9-5 | Fenway Park (0-3) | 38-30 | Lost 3 |
| » W: Greg Harris (3-7) L: Joe Slusarski (2-4) | Second | 4 out |
| Sunday, June 23 |
| » Defeated Red Sox (36-31), 4-2 | Fenway Park (1-3) | 39-30 | |
| » W: Bob Welch (7-4) L: Danny Darwin (3-4) S: Dennis Eckersley (20) | Second | 3 out |
| Tuesday, June 25 |
| » Lost to Rangers (35-30), 6-1 | Oakland-Alameda County Stadium (23-10) | 39-31 | |
| » W: Jose Guzman (2-3) L: Dave Stewart (4-4) | Second | 4½ out |
| Wednesday, June 26 |
| » Lost to Rangers (36-30), 8-1 | Oakland-Alameda County Stadium (23-11) | 39-32 | Lost 2 |
| » W: Kevin Brown (6-5) L: Gene Nelson (1-2) | Third | 4½ out |
| » Major-league debuts: Wayne Rosenthal (Rangers) |
| Thursday, June 27 |
| » Lost to Rangers (37-30), 9-6 | Oakland-Alameda County Stadium (23-12) | 39-33 | Lost 3 |
| » W: Wayne Rosenthal (1-0) L: Rick Honeycutt (0-1) S: Jeff Russell (15) | Fourth | 4½ out |
| Friday, June 28 |
| » Lost to Royals (33-38), 11-0 | Oakland-Alameda County Stadium (23-13) | 39-34 | Lost 4 |
| » W: Luis Aquino (1-1) L: Bob Welch (7-5) | Fourth | 4½ out |
| Saturday, June 29 |
| » Defeated Royals (33-39), 6-3 | Oakland-Alameda County Stadium (24-13) | 40-34 | |
| » W: Dave Stewart (5-4) L: Storm Davis (2-7) S: Dennis Eckersley (21) | Fourth | 3½ out |
| Sunday, June 30 |
| » Defeated Royals (33-40), 3-2 | Oakland-Alameda County Stadium (25-13) | 41-34 | Won 2 |
| » W: Mike Moore (9-6) L: Tom Gordon (4-6) S: Dennis Eckersley (22) | Fourth | 3½ out |
| Monday, July 1 |
| » Lost to Royals (34-40), 7-3 | Oakland-Alameda County Stadium (25-14) | 41-35 | |
| » W: Mike Boddicker (7-6) L: Andy Hawkins (2-5) S: Jeff Montgomery (15) | Fourth | 3½ out |
| Tuesday, July 2 |
| » Lost to Rangers (40-32), 9-6 | Arlington Stadium (0-1) | 41-36 | Lost 2 |
| » W: Kenny Rogers (5-7) L: Rick Honeycutt (0-2) S: Jeff Russell (16) | Fifth | 3½ out |
| Wednesday, July 3 |
| » Defeated Rangers (40-33), 5-0 | Arlington Stadium (1-1) | 42-36 | |
| » W: Dave Stewart (6-4) L: John Barfield (3-3) | Fifth | 2½ out |
| Thursday, July 4 |
| » Lost to Rangers (41-33), 5-4 | Arlington Stadium (1-2) | 42-37 | |
| » W: Jeff Russell (3-1) L: Gene Nelson (1-3) | Fourth | 3½ out |
| Friday, July 5 |
| » Defeated Royals (35-43), 9-3 | Royals Stadium (1-0) | 43-37 | |
| » W: Andy Hawkins (3-5) L: Tom Gordon (4-7) S: Steve Chitren (3) | Fourth | 2½ out |
| Saturday, July 6 |
| » Defeated Royals (35-44), 9-7 | Royals Stadium (2-0) | 44-37 | Won 2 |
| » W: Bob Welch (8-5) L: Mike Boddicker (7-7) S: Dennis Eckersley (23) | Fourth | 2½ out |
| Sunday, July 7 |
| » Lost to Royals (36-44), 7-5 | Royals Stadium (2-1) | 44-38 | |
| » W: Mark Gubicza (4-5) L: Dave Stewart (6-5) | Fifth | 2½ out |
| Thursday, July 11 |
| » Defeated Orioles (33-48), 8-1 | Oakland-Alameda County Stadium (26-14) | 45-38 | |
| » W: Dave Stewart (7-5) L: Jeff Robinson (4-7) | Third | 2½ out |
| Friday, July 12 |
| » Lost to Orioles (34-48), 6-3 | Oakland-Alameda County Stadium (26-15) | 45-39 | |
| » W: Ben McDonald (4-3) L: Curt Young (2-2) S: Gregg Olson (18) | Fourth | 3½ out |
| Saturday, July 13 |
| » Lost to Orioles (35-48), 2-0 | Oakland-Alameda County Stadium (26-16) | 45-40 | Lost 2 |
| » W: Bob Milacki (5-3) L: Eric Show (0-1) S: Gregg Olson (19) | Fourth | 4½ out |
| Sunday, July 14 |
| » Defeated Orioles (35-49), 3-2 | Oakland-Alameda County Stadium (27-16) | 46-40 | |
| » W: Todd Burns (1-0) L: Gregg Olson (1-4) | Fourth | 3½ out |
| Monday, July 15 |
| » Defeated Indians (27-57), 6-1 | Oakland-Alameda County Stadium (28-16) | 47-40 | Won 2 |
| » W: Andy Hawkins (4-5) L: Denis Boucher (0-6) | Fourth | 3½ out |
| Tuesday, July 16 |
| » Defeated Indians (27-58), 7-6 | Oakland-Alameda County Stadium (29-16) | 48-40 | Won 3 |
| » W: Joe Klink (6-2) L: Doug Jones (1-7) | Second | 2½ out |
| Wednesday, July 17 |
| » Lost to Indians (28-58), 2-1 | Oakland-Alameda County Stadium (29-17) | 48-41 | |
| » W: Rod Nichols (1-8) L: Bob Welch (8-6) | Second | 3 out |
| Thursday, July 18 |
| » Lost to Yankees (42-43), 3-2 | Oakland-Alameda County Stadium (29-18) | 48-42 | Lost 2 |
| » W: Scott Kamieniecki (4-1) L: Eric Show (0-2) S: Steve Howe (3) | Third | 4 out |
| Friday, July 19 |
| » Lost to Yankees (43-43), 3-0 | Oakland-Alameda County Stadium (29-19) | 48-43 | Lost 3 |
| » W: Jeff Johnson (3-3) L: Mike Moore (9-7) S: Steve Farr (15) | Fourth | 5 out |
| » Major-league debuts: Kevin Campbell (Athletics) |
| Saturday, July 20 |
| » Lost to Yankees (44-43), 5-1 | Oakland-Alameda County Stadium (29-20) | 48-44 | Lost 4 |
| » W: Wade Taylor (5-4) L: Andy Hawkins (4-6) | Fourth | 6 out |
| Sunday, July 21 |
| » Defeated Yankees (44-44), 4-2 | Oakland-Alameda County Stadium (30-20) | 49-44 | |
| » W: Dave Stewart (8-5) L: Scott Sanderson (10-5) S: Dennis Eckersley (24) | Fourth | 6 out |
| Monday, July 22 |
| » Major-league debuts: Ryan Bowen (Astros) |
| Tuesday, July 23 |
| » Defeated Indians (31-60), 10-7 | Cleveland Stadium (3-1) | 50-44 | Won 2 |
| » W: Rick Honeycutt (1-2) L: Jeff Shaw (0-3) | Fourth | 5 out |
| Wednesday, July 24 |
| » Defeated Indians (31-61), 8-4 | Cleveland Stadium (4-1) | 51-44 | Won 3 |
| » W: Eric Show (1-2) L: Greg Swindell (6-8) | Fourth | 4 out |
| Thursday, July 25 |
| » Lost to Indians (32-61), 8-7 | Cleveland Stadium (4-2) | 51-45 | |
| » W: Mike York (1-2) L: Dennis Eckersley (1-2) S: Steve Olin (4) | Fourth | 5 out |
| Friday, July 26 |
| » Defeated Orioles (39-56), 12-9 | Memorial Stadium (3-1) | 52-45 | |
| » W: Joe Klink (7-2) L: Mark Williamson (3-4) S: Steve Chitren (4) | Third | 5 out |
| Saturday, July 27 |
| » Defeated Orioles (39-57), 9-1 | Memorial Stadium (4-1) | 53-45 | Won 2 |
| » W: Joe Slusarski (3-4) L: Jeff Ballard (6-11) | Third | 5 out |
| Sunday, July 28 |
| » Defeated Orioles (39-58), 4-3 | Memorial Stadium (5-1) | 54-45 | Won 3 |
| » W: Rick Honeycutt (2-2) L: Ben McDonald (4-5) S: Dennis Eckersley (25) | Third | 4 out |
| Monday, July 29 |
| » Defeated Yankees (46-49), 10-8 | Yankee Stadium (2-3) | 55-45 | Won 4 |
| » W: Kevin Campbell (1-0) L: Steve Howe (3-1) S: Dennis Eckersley (26) | Third | 4 out |
| » Major-league debuts: Mike Humphreys (Yankees) |
| Tuesday, July 30 |
| » Defeated Yankees (46-50), 6-5 | Yankee Stadium (3-3) | 56-45 | Won 5 |
| » W: Curt Young (3-2) L: Wade Taylor (5-6) S: Dennis Eckersley (27) | Third | 4 out |
| Wednesday, July 31 |
| » Lost to Red Sox (48-52), 11-10 | Fenway Park (1-4) | 56-46 | |
| » W: Greg Harris (7-11) L: Steve Chitren (1-3) | Third | 5 out |
| Thursday, August 1 |
| » Defeated Red Sox (48-53), 4-2 | Fenway Park (2-4) | 57-46 | |
| » W: Joe Klink (8-2) L: Dennis Lamp (3-2) S: Dennis Eckersley (28) | Third | 4 out |
| Friday, August 2 |
| » Defeated Twins (61-43), 3-1 | Oakland-Alameda County Stadium (31-20) | 58-46 | Won 2 |
| » W: Bob Welch (9-6) L: Jack Morris (13-8) | Third | 3 out |
| Saturday, August 3 |
| » Lost to Twins (62-43), 8-6 | Oakland-Alameda County Stadium (31-21) | 58-47 | |
| » W: Steve Bedrosian (4-2) L: Joe Klink (8-3) S: Rick Aguilera (28) | Third | 4 out |
| Sunday, August 4 |
| » Lost to Twins (63-43), 6-2 | Oakland-Alameda County Stadium (31-22) | 58-48 | Lost 2 |
| » W: Scott Erickson (15-3) L: Dave Stewart (8-6) S: Carl Willis (2) | Third | 5 out |
| Monday, August 5 |
| » Defeated Mariners (57-49), 3-0 | Oakland-Alameda County Stadium (32-22) | 59-48 | |
| » W: Ron Darling (6-8) L: Bill Krueger (9-4) S: Dennis Eckersley (29) | Third | 5 out |
| Tuesday, August 6 |
| » Defeated Mariners (57-50), 3-0 | Oakland-Alameda County Stadium (33-22) | 60-48 | Won 2 |
| » W: Mike Moore (10-7) L: Rich DeLucia (9-7) S: Dennis Eckersley (30) | Third | 5 out |
| » Major-league debuts: Dave Fleming (Mariners) |
| Wednesday, August 7 |
| » Defeated Mariners (57-51), 6-1 | Oakland-Alameda County Stadium (34-22) | 61-48 | Won 3 |
| » W: Bob Welch (10-6) L: Brian Holman (9-11) | Third | 4 out |
| » Major-league debuts: Scott Brosius (Athletics) |
| Friday, August 9 |
| » Defeated Angels (53-55), 5-4 | Anaheim Stadium (4-1) | 62-48 | Won 4 |
| » W: Dave Stewart (9-6) L: Kirk McCaskill (8-15) S: Dennis Eckersley (31) | Third | 4 out |
| Saturday, August 10 |
| » Defeated Angels (53-56), 3-1 | Anaheim Stadium (5-1) | 63-48 | Won 5 |
| » W: Ron Darling (7-8) L: Mark Langston (14-6) S: Dennis Eckersley (32) | Third | 3 out |
| Sunday, August 11 |
| » Defeated Angels (53-57), 3-2 | Anaheim Stadium (6-1) | 64-48 | Won 6 |
| » W: Mike Moore (11-7) L: Joe Grahe (1-3) S: Dennis Eckersley (33) | Third | 3 out |
| Monday, August 12 |
| » Lost to Mariners (59-53), 6-3 | Kingdome (0-4) | 64-49 | |
| » W: Rich DeLucia (10-7) L: Bob Welch (10-7) | Third | 4 out |
| Tuesday, August 13 |
| » Lost to Mariners (60-53), 5-2 | Kingdome (0-5) | 64-50 | Lost 2 |
| » W: Brian Holman (10-11) L: Dave Stewart (9-7) S: Mike Schooler (4) | Third | 4 out |
| Wednesday, August 14 |
| » Lost to Mariners (61-53), 4-0 | Kingdome (0-6) | 64-51 | Lost 3 |
| » W: Randy Johnson (11-8) L: Joe Slusarski (3-5) | Third | 4 out |
| Thursday, August 15 |
| » Lost to Mariners (62-53), 8-6 | Kingdome (0-7) | 64-52 | Lost 4 |
| » W: Calvin Jones (1-1) L: Steve Chitren (1-4) S: Mike Schooler (5) | Third | 4 out |
| Friday, August 16 |
| » Lost to Twins (69-48), 5-4 | Hubert H. Humphrey Metrodome (1-3) | 64-53 | Lost 5 |
| » W: Rick Aguilera (3-4) L: Gene Nelson (1-4) | Third | 5 out |
| Saturday, August 17 |
| » Lost to Twins (70-48), 12-4 | Hubert H. Humphrey Metrodome (1-4) | 64-54 | Lost 6 |
| » W: Jack Morris (15-9) L: Bob Welch (10-8) | Third | 6 out |
| Sunday, August 18 |
| » Lost to Twins (71-48), 6-4 | Hubert H. Humphrey Metrodome (1-5) | 64-55 | Lost 7 |
| » W: Carl Willis (7-2) L: Rick Honeycutt (2-3) S: Rick Aguilera (32) | Third | 7 out |
| Monday, August 19 |
| » Defeated Twins (71-49), 8-7 | Hubert H. Humphrey Metrodome (2-5) | 65-55 | |
| » W: Joe Klink (9-3) L: Steve Bedrosian (4-3) S: Dennis Eckersley (34) | Third | 6 out |
| Tuesday, August 20 |
| » Defeated Angels (58-61), 3-2 | Oakland-Alameda County Stadium (35-22) | 66-55 | Won 2 |
| » W: Ron Darling (8-8) L: Mark Langston (15-7) S: Dennis Eckersley (35) | Third | 6 out |
| Wednesday, August 21 |
| » Defeated Angels (58-62), 2-0 | Oakland-Alameda County Stadium (36-22) | 67-55 | Won 3 |
| » W: Mike Moore (12-7) L: Joe Grahe (1-5) S: Dennis Eckersley (36) | Third | 6 out |
| Thursday, August 22 |
| » Defeated Angels (58-63), 2-1 | Oakland-Alameda County Stadium (37-22) | 68-55 | Won 4 |
| » W: Bob Welch (11-8) L: Chuck Finley (15-7) | Third | 6 out |
| Friday, August 23 |
| » Lost to Brewers (58-64), 13-4 | Oakland-Alameda County Stadium (37-23) | 68-56 | |
| » W: Jaime Navarro (12-9) L: Dave Stewart (9-8) | Third | 6 out |
| Saturday, August 24 |
| » Lost to Brewers (59-64), 7-0 | Oakland-Alameda County Stadium (37-24) | 68-57 | Lost 2 |
| » W: Bill Wegman (9-6) L: Joe Slusarski (3-6) | Third | 7 out |
| Sunday, August 25 |
| » Lost to Brewers (60-64), 8-2 | Oakland-Alameda County Stadium (37-25) | 68-58 | Lost 3 |
| » W: Chris Bosio (10-9) L: Ron Darling (8-9) | Second | 7 out |
| » Major-league debuts: Ron Witmeyer (Athletics) |
| Monday, August 26 |
| » Lost to Red Sox (63-62), 3-0 | Oakland-Alameda County Stadium (37-26) | 68-59 | Lost 4 |
| » W: Roger Clemens (13-8) L: Mike Moore (12-8) | Third | 8 out |
| Tuesday, August 27 |
| » Lost to Red Sox (64-62), 6-4 | Oakland-Alameda County Stadium (37-27) | 68-60 | Lost 5 |
| » W: Mike Gardiner (6-6) L: Bob Welch (11-9) S: Jeff Reardon (32) | Third | 8 out |
| Wednesday, August 28 |
| » Defeated Red Sox (64-63), 9-3 | Oakland-Alameda County Stadium (38-27) | 69-60 | |
| » W: Dave Stewart (10-8) L: Matt Young (3-5) | Second | 8 out |
| Friday, August 30 |
| » Defeated Tigers (69-60), 6-3 | Oakland-Alameda County Stadium (39-27) | 70-60 | Won 2 |
| » W: Dennis Eckersley (2-2) L: Jerry Don Gleaton (3-2) | Second | 7 out |
| Saturday, August 31 |
| » Defeated Tigers (69-61), 9-8 | Oakland-Alameda County Stadium (40-27) | 71-60 | Won 3 |
| » W: Dennis Eckersley (3-2) L: John Cerutti (2-6) | Second | 7 out |
| Sunday, September 1 |
| » Lost to Tigers (70-61), 5-2 | Oakland-Alameda County Stadium (40-28) | 71-61 | |
| » W: Mark Leiter (8-2) L: Bob Welch (11-10) S: Jerry Don Gleaton (2) | Second | 8 out |
| Tuesday, September 3 |
| » Lost to Brewers (64-68), 5-3 | County Stadium (1-4) | 71-62 | Lost 2 |
| » W: Edwin Nunez (2-1) L: Dennis Eckersley (3-3) | Second | 9 out |
| Wednesday, September 4 |
| » Lost to Brewers (65-68), 2-0 | County Stadium (1-5) | 71-63 | Lost 3 |
| » W: Bill Wegman (11-6) L: Ron Darling (8-10) S: Doug Henry (6) | Third | 9 out |
| Thursday, September 5 |
| » Defeated Tigers (71-63), 4-1 | Tiger Stadium (2-1) | 72-63 | |
| » W: Mike Moore (13-8) L: Frank Tanana (11-9) S: Dennis Eckersley (37) | Third | 8½ out |
| Friday, September 6 |
| » Lost to Tigers (72-63), 11-2 | Tiger Stadium (2-2) | 72-64 | |
| » W: Walt Terrell (11-10) L: Bob Welch (11-11) | Third | 9½ out |
| » Major-league debuts: Shawn Hare (Tigers) |
| Saturday, September 7 |
| » Defeated Tigers (72-64), 3-1 | Tiger Stadium (3-2) | 73-64 | |
| » W: Joe Slusarski (4-6) L: Mark Leiter (8-3) S: Dennis Eckersley (38) | Third | 9½ out |
| Sunday, September 8 |
| » Defeated Tigers (72-65), 7-4 | Tiger Stadium (4-2) | 74-64 | Won 2 |
| » W: Dave Stewart (11-8) L: Bill Gullickson (17-8) S: Dennis Eckersley (39) | Third | 9½ out |
| » Major-league debuts: Dave Haas (Tigers) |
| Monday, September 9 |
| » Lost to White Sox (76-63), 7-1 | Oakland-Alameda County Stadium (40-29) | 74-65 | |
| » W: Alex Fernandez (8-12) L: Ron Darling (8-11) | Third | 10½ out |
| Tuesday, September 10 |
| » Lost to White Sox (77-63), 3-1 | Oakland-Alameda County Stadium (40-30) | 74-66 | Lost 2 |
| » W: Melido Perez (7-4) L: Rick Honeycutt (2-4) S: Bobby Thigpen (29) | Third | 11½ out |
| Wednesday, September 11 |
| » Defeated White Sox (77-64), 6-5 | Oakland-Alameda County Stadium (41-30) | 75-66 | |
| » W: Dennis Eckersley (4-3) L: Steve Wapnick (0-1) | Third | 10½ out |
| » Major-league debuts: Todd Van Poppel (Athletics) |
| Friday, September 13 |
| » Lost to Blue Jays (80-62), 7-6 | Skydome (2-2) | 75-67 | |
| » W: Juan Guzman (7-2) L: Dave Stewart (11-9) S: Tom Henke (32) | Fourth | 11 out |
| Saturday, September 14 |
| » Lost to Blue Jays (81-62), 6-0 | Skydome (2-3) | 75-68 | Lost 2 |
| » W: Tom Candiotti (13-1 |