| Monday, April 9 |
| » Lost to Athletics (1-0), 8-3 | Oakland-Alameda County Stadium (0-1) | 0-1 | |
| » W: Dave Stewart (1-0) L: Allan Anderson (0-1) S: Rick Honeycutt (1) | Second | 1 out |
| Tuesday, April 10 |
| » Lost to Athletics (2-0), 5-3 | Oakland-Alameda County Stadium (0-2) | 0-2 | Lost 2 |
| » W: Bob Welch (1-0) L: Roy Smith (0-1) S: Dennis Eckersley (1) | Fourth | 2 out |
| Wednesday, April 11 |
| » Defeated Athletics (2-1), 3-0 | Oakland-Alameda County Stadium (1-2) | 1-2 | |
| » W: Kevin Tapani (1-0) L: Mike Moore (0-1) S: Rick Aguilera (1) | Fourth | 1½ out |
| » Major-league debuts: Mike Bordick (Athletics) |
| Thursday, April 12 |
| » Lost to Angels (3-1), 3-1 | Anaheim Stadium (0-1) | 1-3 | |
| » W: Kirk McCaskill (1-0) L: David West (0-1) S: Mark Eichhorn (2) | Seventh | 2 out |
| Friday, April 13 |
| » Defeated Angels (3-2), 7-4 | Anaheim Stadium (1-1) | 2-3 | |
| » W: Allan Anderson (1-1) L: Mike Witt (0-1) S: Rick Aguilera (2) | Fourth | 1½ out |
| Saturday, April 14 |
| » Lost to Angels (4-2), 7-5 | Anaheim Stadium (1-2) | 2-4 | |
| » W: Bryan Harvey (1-0) L: Rick Aguilera (0-1) | Sixth | 2½ out |
| Sunday, April 15 |
| » Lost to Angels (5-2), 4-1 | Anaheim Stadium (1-3) | 2-5 | Lost 2 |
| » W: Chuck Finley (2-0) L: Kevin Tapani (1-1) S: Bryan Harvey (1) | Sixth | 3½ out |
| Monday, April 16 |
| » Lost to Mariners (2-5), 6-3 | Kingdome (0-1) | 2-6 | Lost 3 |
| » W: Randy Johnson (1-1) L: David West (0-2) S: Mike Schooler (2) | Seventh | 4 out |
| Tuesday, April 17 |
| » Defeated Mariners (2-6), 6-5 | Kingdome (1-1) | 3-6 | |
| » W: Juan Berenguer (1-0) L: Keith Comstock (0-1) S: Rick Aguilera (3) | Sixth | 4 out |
| Wednesday, April 18 |
| » Defeated Mariners (2-7), 4-3 | Kingdome (2-1) | 4-6 | Won 2 |
| » W: Terry Leach (1-0) L: Matt Young (0-2) S: Rick Aguilera (4) | Sixth | 4 out |
| Friday, April 20 |
| » Defeated Angels (5-5), 13-1 | Hubert H. Humphrey Metrodome (1-0) | 5-6 | Won 3 |
| » W: Kevin Tapani (2-1) L: Jim Abbott (0-1) | Fourth | 3½ out |
| Saturday, April 21 |
| » Defeated Angels (5-6), 8-0 | Hubert H. Humphrey Metrodome (2-0) | 6-6 | Won 4 |
| » W: David West (1-2) L: Bert Blyleven (0-2) S: John Candelaria (1) | Third | 3½ out |
| Sunday, April 22 |
| » Lost to Angels (6-6), 5-2 | Hubert H. Humphrey Metrodome (2-1) | 6-7 | |
| » W: Chuck Finley (3-0) L: Allan Anderson (1-2) S: Mark Eichhorn (3) | Fifth | 3½ out |
| Monday, April 23 |
| » Lost to Tigers (6-8), 6-3 | Hubert H. Humphrey Metrodome (2-2) | 6-8 | Lost 2 |
| » W: Frank Tanana (1-1) L: Roy Smith (0-2) S: Mike Henneman (4) | Fifth | 4 out |
| Tuesday, April 24 |
| » Defeated Tigers (6-9), 16-4 | Hubert H. Humphrey Metrodome (3-2) | 7-8 | |
| » W: John Candelaria (1-0) L: Kevin Ritz (0-4) | Fourth | 4 out |
| Wednesday, April 25 |
| » Lost to Tigers (7-9), 6-4 | Hubert H. Humphrey Metrodome (3-3) | 7-9 | |
| » W: Jeff Robinson (1-1) L: Kevin Tapani (2-2) S: Mike Henneman (5) | Fifth | 5 out |
| Friday, April 27 |
| » Lost to Indians (7-8), 7-2 | Cleveland Stadium (0-1) | 7-10 | Lost 2 |
| » W: Bud Black (2-0) L: David West (1-3) | Fifth | 5½ out |
| Saturday, April 28 |
| » Lost to Indians (8-8), 3-0 | Cleveland Stadium (0-2) | 7-11 | Lost 3 |
| » W: John Farrell (2-1) L: Allan Anderson (1-3) S: Jesse Orosco (1) | Sixth | 5½ out |
| Sunday, April 29 |
| » Lost to Indians (9-8), 6-4 | Cleveland Stadium (0-3) | 7-12 | Lost 4 |
| » W: Greg Swindell (2-2) L: Roy Smith (0-3) S: Doug Jones (6) | Sixth | 6½ out |
| Tuesday, May 1 |
| » Defeated Tigers (8-13), 9-5 | Tiger Stadium (1-0) | 8-12 | |
| » W: John Candelaria (2-0) L: Paul Gibson (0-1) | Fifth | 7 out |
| Wednesday, May 2 |
| » Defeated Tigers (8-14), 8-2 | Tiger Stadium (2-0) | 9-12 | Won 2 |
| » W: David West (2-3) L: Jack Morris (2-3) | Fifth | 7 out |
| Thursday, May 3 |
| » Defeated Tigers (8-15), 3-1 | Tiger Stadium (3-0) | 10-12 | Won 3 |
| » W: Terry Leach (2-0) L: Mike Henneman (0-2) S: Rick Aguilera (5) | Fourth | 6½ out |
| Saturday, May 5 |
| » Defeated Brewers (14-7), 9-5 | County Stadium (1-0) | 11-12 | Won 4 |
| » W: John Candelaria (3-0) L: Chuck Crim (1-1) | Fourth | 6 out |
| Sunday, May 6 |
| » Defeated Brewers (14-8), 4-0 | County Stadium (2-0) | 12-12 | Won 5 |
| » W: Kevin Tapani (3-2) L: Teddy Higuera (3-1) | Fourth | 6 out |
| Tuesday, May 8 |
| » Defeated Indians (13-13), 6-5 | Hubert H. Humphrey Metrodome (4-3) | 13-12 | Won 6 |
| » W: Juan Berenguer (2-0) L: Steve Olin (0-2) S: Rick Aguilera (6) | Third | 6½ out |
| Wednesday, May 9 |
| » Lost to Indians (14-13), 7-3 | Hubert H. Humphrey Metrodome (4-4) | 13-13 | |
| » W: Sergio Valdez (1-0) L: John Candelaria (3-1) S: Doug Jones (10) | Fourth | 7½ out |
| Thursday, May 10 |
| » Defeated Indians (14-14), 3-2 | Hubert H. Humphrey Metrodome (5-4) | 14-13 | |
| » W: Roy Smith (1-3) L: Greg Swindell (2-3) S: Rick Aguilera (7) | Third | 7 out |
| Friday, May 11 |
| » Lost to Brewers (17-9), 6-3 | Hubert H. Humphrey Metrodome (5-5) | 14-14 | |
| » W: Bill Wegman (1-0) L: Allan Anderson (1-4) S: Dan Plesac (7) | Third | 8 out |
| Saturday, May 12 |
| » Defeated Brewers (17-10), 5-2 | Hubert H. Humphrey Metrodome (6-5) | 15-14 | |
| » W: Kevin Tapani (4-2) L: Mark Knudson (2-1) S: Rick Aguilera (8) | Third | 7 out |
| Sunday, May 13 |
| » Defeated Brewers (17-11), 8-6 | Hubert H. Humphrey Metrodome (7-5) | 16-14 | Won 2 |
| » W: Juan Berenguer (3-0) L: Bill Krueger (2-1) S: Rick Aguilera (9) | Third | 6 out |
| Monday, May 14 |
| » Defeated Athletics (22-9), 6-2 | Hubert H. Humphrey Metrodome (8-5) | 17-14 | Won 3 |
| » W: Allan Anderson (2-4) L: Dave Stewart (6-1) | Third | 5 out |
| Tuesday, May 15 |
| » Lost to Yankees (13-17), 7-3 | Yankee Stadium (0-1) | 17-15 | |
| » W: Chuck Cary (1-0) L: Roy Smith (1-4) | Third | 5 out |
| Thursday, May 17 |
| » Defeated Yankees (13-18), 4-1 | Yankee Stadium (1-1) | 18-15 | |
| » W: Kevin Tapani (5-2) L: Dave LaPoint (2-3) S: Rick Aguilera (10) | Third | 5 out |
| Friday, May 18 |
| » Defeated Red Sox (18-15), 6-0 | Fenway Park (1-0) | 19-15 | Won 2 |
| » W: John Candelaria (4-1) L: Greg Harris (4-2) | Third | 4 out |
| Saturday, May 19 |
| » Lost to Red Sox (19-15), 13-1 | Fenway Park (1-1) | 19-16 | |
| » W: Roger Clemens (6-2) L: Allan Anderson (2-5) | Third | 5 out |
| Sunday, May 20 |
| » Defeated Red Sox (19-16), 5-4 | Fenway Park (2-1) | 20-16 | |
| » W: Roy Smith (2-4) L: Eric Hetzel (1-3) S: Rick Aguilera (11) | Third | 4 out |
| Monday, May 21 |
| » Defeated Orioles (16-22), 7-3 | Memorial Stadium (1-0) | 21-16 | Won 2 |
| » W: Mark Guthrie (1-0) L: Bob Milacki (1-3) | Third | 4 out |
| Tuesday, May 22 |
| » Lost to Orioles (17-22), 10-2 | Memorial Stadium (1-1) | 21-17 | |
| » W: Mark Williamson (3-1) L: Kevin Tapani (5-3) | Third | 5 out |
| Wednesday, May 23 |
| » Lost to Yankees (16-21), 12-0 | Hubert H. Humphrey Metrodome (8-6) | 21-18 | Lost 2 |
| » W: Tim Leary (3-4) L: Tim Drummond (0-1) | Third | 6 out |
| Thursday, May 24 |
| » Defeated Yankees (16-22), 5-4 | Hubert H. Humphrey Metrodome (9-6) | 22-18 | |
| » W: Rick Aguilera (1-1) L: Greg Cadaret (1-4) | Third | 6 out |
| Friday, May 25 |
| » Defeated Red Sox (21-19), 16-0 | Hubert H. Humphrey Metrodome (10-6) | 23-18 | Won 2 |
| » W: Roy Smith (3-4) L: Eric Hetzel (1-4) | Third | 6 out |
| Saturday, May 26 |
| » Defeated Red Sox (21-20), 6-5 | Hubert H. Humphrey Metrodome (11-6) | 24-18 | Won 3 |
| » W: John Candelaria (5-1) L: Rob Murphy (0-2) S: Rick Aguilera (12) | Third | 6 out |
| Sunday, May 27 |
| » Defeated Red Sox (21-21), 3-1 | Hubert H. Humphrey Metrodome (12-6) | 25-18 | Won 4 |
| » W: Kevin Tapani (6-3) L: Dana Kiecker (0-2) S: Rick Aguilera (13) | Third | 5½ out |
| Monday, May 28 |
| » Defeated Orioles (20-25), 6-4 | Hubert H. Humphrey Metrodome (13-6) | 26-18 | Won 5 |
| » W: Juan Berenguer (4-0) L: Joe Price (0-2) S: John Candelaria (2) | Third | 4½ out |
| Tuesday, May 29 |
| » Lost to Orioles (21-25), 5-1 | Hubert H. Humphrey Metrodome (13-7) | 26-19 | |
| » W: Bob Milacki (2-3) L: Allan Anderson (2-6) | Third | 4½ out |
| Wednesday, May 30 |
| » Defeated Orioles (21-26), 12-3 | Hubert H. Humphrey Metrodome (14-7) | 27-19 | |
| » W: Roy Smith (4-4) L: Pete Harnisch (5-2) | Third | 4½ out |
| Thursday, May 31 |
| » Defeated White Sox (28-16), 3-2 | Comiskey Park I (1-0) | 28-19 | Won 2 |
| » W: Mark Guthrie (2-0) L: Jerry Kutzler (2-1) S: Rick Aguilera (14) | Third | 4½ out |
| Friday, June 1 |
| » Lost to White Sox (29-16), 2-1 | Comiskey Park I (1-1) | 28-20 | |
| » W: Barry Jones (7-0) L: Terry Leach (2-1) | Third | 5½ out |
| Saturday, June 2 |
| » Defeated White Sox (29-17), 2-1 | Comiskey Park I (2-1) | 29-20 | |
| » W: John Candelaria (6-1) L: Eric King (4-1) S: Rick Aguilera (15) | Third | 4½ out |
| Sunday, June 3 |
| » Lost to White Sox (30-17), 5-2 | Comiskey Park I (2-2) | 29-21 | |
| » W: Jack McDowell (2-3) L: Allan Anderson (2-7) S: Bobby Thigpen (17) | Third | 4½ out |
| Tuesday, June 5 |
| » Lost to Blue Jays (28-25), 7-3 | Skydome (0-1) | 29-22 | Lost 2 |
| » W: David Wells (3-1) L: Roy Smith (4-5) | Third | 5½ out |
| Wednesday, June 6 |
| » Defeated Blue Jays (28-26), 12-5 | Skydome (1-1) | 30-22 | |
| » W: John Candelaria (7-1) L: Willie Blair (0-2) | Third | 5½ out |
| Thursday, June 7 |
| » Lost to Blue Jays (29-26), 10-3 | Skydome (1-2) | 30-23 | |
| » W: Todd Stottlemyre (5-6) L: Kevin Tapani (6-4) | Third | 5½ out |
| » Major-league debuts: Tom Gilles (Blue Jays) |
| Friday, June 8 |
| » Lost to White Sox (32-19), 3-2 | Hubert H. Humphrey Metrodome (14-8) | 30-24 | Lost 2 |
| » W: Scott Radinsky (5-0) L: Juan Berenguer (4-1) S: Bobby Thigpen (18) | Third | 6½ out |
| Saturday, June 9 |
| » Lost to White Sox (33-19), 4-2 | Hubert H. Humphrey Metrodome (14-9) | 30-25 | Lost 3 |
| » W: Eric King (5-1) L: Allan Anderson (2-8) S: Bobby Thigpen (19) | Third | 7½ out |
| Sunday, June 10 |
| » Lost to White Sox (34-19), 5-3 | Hubert H. Humphrey Metrodome (14-10) | 30-26 | Lost 4 |
| » W: Greg Hibbard (5-4) L: Roy Smith (4-6) S: Bobby Thigpen (20) | Third | 8½ out |
| Tuesday, June 12 |
| » Lost to Blue Jays (33-27), 5-4 | Hubert H. Humphrey Metrodome (14-11) | 30-27 | Lost 5 |
| » W: Todd Stottlemyre (6-6) L: John Candelaria (7-2) S: Duane Ward (5) | Third | 8 out |
| Wednesday, June 13 |
| » Lost to Blue Jays (34-27), 10-1 | Hubert H. Humphrey Metrodome (14-12) | 30-28 | Lost 6 |
| » W: John Cerutti (3-5) L: David West (2-4) S: Tom Henke (9) | Third | 9 out |
| Thursday, June 14 |
| » Lost to Blue Jays (35-27), 7-1 | Hubert H. Humphrey Metrodome (14-13) | 30-29 | Lost 7 |
| » W: Dave Stieb (9-2) L: Allan Anderson (2-9) | Fourth | 9 out |
| Friday, June 15 |
| » Lost to Royals (24-35), 5-1 | Royals Stadium (0-1) | 30-30 | Lost 8 |
| » W: Kevin Appier (2-2) L: Tim Drummond (0-2) | Third | 10 out |
| Saturday, June 16 |
| » Lost to Royals (25-35), 5-3 | Royals Stadium (0-2) | 30-31 | Lost 9 |
| » W: Tom Gordon (3-4) L: Mark Guthrie (2-1) | Third | 11 out |
| Sunday, June 17 |
| » Defeated Royals (25-36), 4-1 | Royals Stadium (1-2) | 31-31 | |
| » W: Kevin Tapani (7-4) L: Bret Saberhagen (5-6) S: Rick Aguilera (16) | Third | 11 out |
| Monday, June 18 |
| » Lost to Rangers (28-37), 7-1 | Arlington Stadium (0-1) | 31-32 | |
| » W: Charlie Hough (7-4) L: David West (2-5) | Fourth | 11 out |
| Tuesday, June 19 |
| » Lost to Rangers (29-37), 5-4 | Arlington Stadium (0-2) | 31-33 | Lost 2 |
| » W: Brad Arnsberg (2-1) L: John Candelaria (7-3) S: Kenny Rogers (4) | Fourth | 11 out |
| Wednesday, June 20 |
| » Lost to Rangers (30-37), 8-0 | Arlington Stadium (0-3) | 31-34 | Lost 3 |
| » W: Kevin Brown (9-4) L: Tim Drummond (0-3) | Fifth | 12 out |
| Thursday, June 21 |
| » Lost to Royals (28-37), 14-4 | Hubert H. Humphrey Metrodome (14-14) | 31-35 | Lost 4 |
| » W: Tom Gordon (4-4) L: Mark Guthrie (2-2) S: Andy McGaffigan (1) | Fifth | 12½ out |
| Friday, June 22 |
| » Defeated Royals (28-38), 3-2 | Hubert H. Humphrey Metrodome (15-14) | 32-35 | |
| » W: Kevin Tapani (8-4) L: Bret Saberhagen (5-7) S: Rick Aguilera (17) | Fourth | 11½ out |
| Saturday, June 23 |
| » Defeated Royals (28-39), 5-1 | Hubert H. Humphrey Metrodome (16-14) | 33-35 | Won 2 |
| » W: David West (3-5) L: Mark Gubicza (4-7) S: Jack Savage (1) | Fourth | 10½ out |
| Sunday, June 24 |
| » Lost to Royals (29-39), 11-2 | Hubert H. Humphrey Metrodome (16-15) | 33-36 | |
| » W: Storm Davis (2-5) L: Allan Anderson (2-10) | Fifth | 10½ out |
| Monday, June 25 |
| » Defeated Rangers (31-40), 9-1 | Hubert H. Humphrey Metrodome (17-15) | 34-36 | |
| » W: Scott Erickson (1-0) L: Mike Jeffcoat (1-3) S: John Candelaria (3) | Fourth | 10½ out |
| » Major-league debuts: Scott Erickson (Twins) |
| Tuesday, June 26 |
| » Defeated Rangers (31-41), 5-4 | Hubert H. Humphrey Metrodome (18-15) | 35-36 | Won 2 |
| » W: Juan Berenguer (5-1) L: Kevin Brown (9-5) S: Rick Aguilera (18) | Fourth | 10½ out |
| Wednesday, June 27 |
| » Lost to Rangers (32-41), 9-2 | Hubert H. Humphrey Metrodome (18-16) | 35-37 | |
| » W: Nolan Ryan (7-4) L: Kevin Tapani (8-5) | Fourth | 10½ out |
| Thursday, June 28 |
| » Lost to Rangers (33-41), 8-6 | Hubert H. Humphrey Metrodome (18-17) | 35-38 | Lost 2 |
| » W: Bobby Witt (4-8) L: David West (3-6) | Fifth | 11 out |
| Friday, June 29 |
| » Lost to Orioles (33-41), 6-2 | Hubert H. Humphrey Metrodome (18-18) | 35-39 | Lost 3 |
| » W: Dave Johnson (7-4) L: Allan Anderson (2-11) S: Curt Schilling (1) | Fifth | 12 out |
| Saturday, June 30 |
| » Lost to Orioles (34-41), 6-0 | Hubert H. Humphrey Metrodome (18-19) | 35-40 | Lost 4 |
| » W: Bob Milacki (4-4) L: Scott Erickson (1-1) | Fifth | 13 out |
| Sunday, July 1 |
| » Defeated Orioles (34-42), 4-3 | Hubert H. Humphrey Metrodome (19-19) | 36-40 | |
| » W: Rick Aguilera (2-1) L: Gregg Olson (4-3) | Fifth | 12 out |
| Tuesday, July 3 |
| » Defeated Red Sox (45-32), 7-3 | Hubert H. Humphrey Metrodome (20-19) | 37-40 | Won 2 |
| » W: Kevin Tapani (9-5) L: Roger Clemens (12-4) S: Rick Aguilera (19) | Fifth | 12½ out |
| Wednesday, July 4 |
| » Lost to Red Sox (46-32), 4-3 | Hubert H. Humphrey Metrodome (20-20) | 37-41 | |
| » W: Dennis Lamp (2-2) L: Rick Aguilera (2-2) S: Jeff Reardon (14) | Fifth | 12½ out |
| Thursday, July 5 |
| » Defeated Red Sox (46-33), 7-4 | Hubert H. Humphrey Metrodome (21-20) | 38-41 | |
| » W: Tim Drummond (1-3) L: Rob Murphy (0-5) S: Rick Aguilera (20) | Fourth | 11½ out |
| Friday, July 6 |
| » Defeated Yankees (28-49), 2-0 | Yankee Stadium (2-1) | 39-41 | Won 2 |
| » W: Juan Berenguer (6-1) L: Andy Hawkins (1-6) S: Rick Aguilera (21) | Fifth | 11½ out |
| » Lost to Yankees (29-49), 5-3 | Yankee Stadium (2-2) | 39-42 | |
| » W: Dave LaPoint (5-6) L: Roy Smith (4-7) S: Dave Righetti (17) | Fifth | 11½ out |
| Saturday, July 7 |
| » Lost to Yankees (30-49), 5-4 | Yankee Stadium (2-3) | 39-43 | Lost 2 |
| » W: Lee Guetterman (6-3) L: Terry Leach (2-2) | Fifth | 11½ out |
| Sunday, July 8 |
| » Defeated Yankees (30-50), 6-3 | Yankee Stadium (3-3) | 40-43 | |
| » W: David West (4-6) L: Tim Leary (3-12) S: Tim Drummond (1) | Fifth | 11½ out |
| Wednesday, July 11 |
| » Lost to Athletics (52-31), 11-7 | Hubert H. Humphrey Metrodome (21-21) | 40-44 | |
| » W: Scott Sanderson (10-5) L: Allan Anderson (2-12) S: Dennis Eckersley (26) | Fifth | 12½ out |
| Friday, July 13 |
| » Lost to Orioles (39-45), 8-5 | Memorial Stadium (1-2) | 40-45 | Lost 2 |
| » W: Mark Williamson (6-1) L: Juan Berenguer (6-2) S: Gregg Olson (19) | Sixth | 12½ out |
| » Defeated Orioles (39-46), 3-1 | Memorial Stadium (2-2) | 41-45 | |
| » W: David West (5-6) L: Dave Johnson (8-5) S: Terry Leach (1) | Sixth | 12½ out |
| Saturday, July 14 |
| » Lost to Orioles (40-46), 3-2 | Memorial Stadium (2-3) | 41-46 | |
| » W: Mark Williamson (7-1) L: Terry Leach (2-3) | Sixth | 13½ out |
| Sunday, July 15 |
| » Defeated Orioles (40-47), 10-3 | Memorial Stadium (3-3) | 42-46 | |
| » W: Allan Anderson (3-12) L: Bob Milacki (4-6) | Sixth | 13½ out |
| Monday, July 16 |
| » Defeated Red Sox (47-40), 3-2 | Fenway Park (3-1) | 43-46 | Won 2 |
| » W: Juan Berenguer (7-2) L: Jeff Gray (1-3) S: Rick Aguilera (22) | Fifth | 13½ out |
| Tuesday, July 17 |
| » Lost to Red Sox (48-40), 1-0 | Fenway Park (3-2) | 43-47 | |
| » W: Tom Bolton (3-0) L: Scott Erickson (1-2) S: Jeff Reardon (16) | Fifth | 13½ out |
| Wednesday, July 18 |
| » Lost to Red Sox (49-40), 5-4 | Fenway Park (3-3) | 43-48 | Lost 2 |
| » W: Dennis Lamp (3-2) L: Juan Berenguer (7-3) S: Jeff Reardon (17) | Sixth | 15 out |
| Thursday, July 19 |
| » Lost to Yankees (33-55), 2-1 | Hubert H. Humphrey Metrodome (21-22) | 43-49 | Lost 3 |
| » W: Tim Leary (4-12) L: Roy Smith (4-8) S: Dave Righetti (20) | Sixth | 15½ out |
| Friday, July 20 |
| » Defeated Yankees (33-56), 2-1 | Hubert H. Humphrey Metrodome (22-22) | 44-49 | |
| » W: Allan Anderson (4-12) L: Dave LaPoint (5-7) | Sixth | 14½ out |
| Saturday, July 21 |
| » Defeated Yankees (33-57), 2-1 | Hubert H. Humphrey Metrodome (23-22) | 45-49 | Won 2 |
| » W: Mark Guthrie (3-2) L: Jeff Robinson (2-6) S: Rick Aguilera (23) | Sixth | 13½ out |
| Sunday, July 22 |
| » Lost to Yankees (34-57), 10-6 | Hubert H. Humphrey Metrodome (23-23) | 45-50 | |
| » W: Greg Cadaret (3-4) L: Rick Aguilera (2-3) | Sixth | 14½ out |
| Tuesday, July 24 |
| » Lost to Mariners (50-47), 8-2 | Hubert H. Humphrey Metrodome (23-24) | 45-51 | Lost 2 |
| » W: Matt Young (5-10) L: David West (5-7) | Sixth | 16 out |
| Wednesday, July 25 |
| » Defeated Mariners (50-48), 6-0 | Hubert H. Humphrey Metrodome (24-24) | 46-51 | |
| » W: Kevin Tapani (10-5) L: Randy Johnson (9-6) S: John Candelaria (4) | Seventh | 16 out |
| Thursday, July 26 |
| » Lost to Mariners (51-48), 6-4 | Hubert H. Humphrey Metrodome (24-25) | 46-52 | |
| » W: Bill Swift (4-2) L: Allan Anderson (4-13) S: Mike Schooler (27) | Seventh | 16 out |
| Friday, July 27 |
| » Defeated Athletics (62-37), 9-4 | Hubert H. Humphrey Metrodome (25-25) | 47-52 | |
| » W: Roy Smith (5-8) L: Mike Moore (9-9) | Sixth | 15 out |
| Saturday, July 28 |
| » Lost to Athletics (63-37), 4-1 | Hubert H. Humphrey Metrodome (25-26) | 47-53 | |
| » W: Dave Stewart (13-8) L: Mark Guthrie (3-3) | Fifth | 15 out |
| » Defeated Athletics (63-38), 9-4 | Hubert H. Humphrey Metrodome (26-26) | 48-53 | |
| » W: Scott Erickson (2-2) L: Bob Welch (16-4) | Fifth | 15 out |
| Sunday, July 29 |
| » Defeated Athletics (63-39), 6-5 | Hubert H. Humphrey Metrodome (27-26) | 49-53 | Won 2 |
| » W: Rick Aguilera (3-3) L: Rick Honeycutt (1-2) | Fifth | 14 out |
| Monday, July 30 |
| » Defeated Angels (49-54), 7-3 | Hubert H. Humphrey Metrodome (28-26) | 50-53 | Won 3 |
| » W: Kevin Tapani (11-5) L: Bert Blyleven (8-7) S: Terry Leach (2) | Fifth | 14 out |
| Tuesday, July 31 |
| » Lost to Angels (50-54), 13-2 | Hubert H. Humphrey Metrodome (28-27) | 50-54 | |
| » W: Chuck Finley (14-4) L: Allan Anderson (4-14) | Fifth | 14 out |
| Wednesday, August 1 |
| » Lost to Angels (51-54), 11-5 | Hubert H. Humphrey Metrodome (28-28) | 50-55 | Lost 2 |
| » W: Mark Langston (5-13) L: Roy Smith (5-9) S: Bryan Harvey (13) | Sixth | 15 out |
| Thursday, August 2 |
| » Lost to Mariners (55-51), 7-2 | Kingdome (2-2) | 50-56 | Lost 3 |
| » W: Brian Holman (11-7) L: Mark Guthrie (3-4) | Sixth | 16 out |
| Friday, August 3 |
| » Defeated Mariners (55-52), 6-2 | Kingdome (3-2) | 51-56 | |
| » W: Rick Aguilera (4-3) L: Mike Schooler (1-3) | Fifth | 16 out |
| Saturday, August 4 |
| » Lost to Mariners (56-52), 4-3 | Kingdome (3-3) | 51-57 | |
| » W: Mike Jackson (5-3) L: Jack Savage (0-1) | Sixth | 16 out |
| Sunday, August 5 |
| » Lost to Mariners (57-52), 4-0 | Kingdome (3-4) | 51-58 | Lost 2 |
| » W: Gene Harris (1-1) L: Allan Anderson (4-15) S: Keith Comstock (1) | Sixth | 17 out |
| Monday, August 6 |
| » Lost to Brewers (46-61), 6-0 | Hubert H. Humphrey Metrodome (28-29) | 51-59 | Lost 3 |
| » W: Ron Robinson (7-5) L: Roy Smith (5-10) | Seventh | 17½ out |
| Tuesday, August 7 |
| » Lost to Brewers (47-61), 5-3 | Hubert H. Humphrey Metrodome (28-30) | 51-60 | Lost 4 |
| » W: Jaime Navarro (3-3) L: Mark Guthrie (3-5) S: Tom Edens (2) | Seventh | 18½ out |
| Wednesday, August 8 |
| » Defeated Brewers (47-62), 4-2 | Hubert H. Humphrey Metrodome (29-30) | 52-60 | |
| » W: Scott Erickson (3-2) L: Mark Knudson (8-6) S: Rick Aguilera (24) | Seventh | 17½ out |
| Friday, August 10 |
| » Defeated Blue Jays (59-54), 7-3 | Skydome (2-2) | 53-60 | Won 2 |
| » W: David West (6-7) L: John Cerutti (8-8) | Sixth | 18 out |
| Saturday, August 11 |
| » Lost to Blue Jays (60-54), 7-4 | Skydome (2-3) | 53-61 | |
| » W: Dave Stieb (15-4) L: Terry Leach (2-4) S: Tom Henke (24) | Seventh | 19 out |
| Sunday, August 12 |
| » Defeated Blue Jays (60-55), 5-4 | Skydome (3-3) | 54-61 | |
| » W: Allan Anderson (5-15) L: Jimmy Key (7-6) | Seventh | 19 out |
| Tuesday, August 14 |
| » Defeated Indians (54-62), 5-4 | Cleveland Stadium (1-3) | 55-61 | Won 2 |
| » W: Mark Guthrie (4-5) L: Bud Black (10-8) S: Rick Aguilera (25) | Seventh | 18½ out |
| Wednesday, August 15 |
| » Lost to Indians (55-62), 5-4 | Cleveland Stadium (1-4) | 55-62 | |
| » W: Jesse Orosco (4-4) L: Tim Drummond (1-4) S: Doug Jones (32) | Seventh | 19½ out |
| Thursday, August 16 |
| » Lost to Indians (56-62), 7-5 | Cleveland Stadium (1-5) | 55-63 | Lost 2 |
| » W: Greg Swindell (9-7) L: Kevin Tapani (11-6) S: Doug Jones (33) | Seventh | 20 out |
| Friday, August 17 |
| » Lost to Blue Jays (63-56), 5-1 | Hubert H. Humphrey Metrodome (29-31) | 55-64 | Lost 3 |
| » W: Dave Stieb (16-4) L: Scott Erickson (3-3) S: Duane Ward (9) | Seventh | 21 out |
| Saturday, August 18 |
| » Lost to Blue Jays (64-56), 3-0 | Hubert H. Humphrey Metrodome (29-32) | 55-65 | Lost 4 |
| » W: Jimmy Key (8-6) L: Allan Anderson (5-16) S: Tom Henke (26) | Sixth | 22 out |
| Sunday, August 19 |
| » Lost to Blue Jays (65-56), 9-1 | Hubert H. Humphrey Metrodome (29-33) | 55-66 | Lost 5 |
| » W: David Wells (9-3) L: Mark Guthrie (4-6) | Sixth | 22 out |
| Monday, August 20 |
| » Lost to Royals (59-62), 7-1 | Royals Stadium (1-3) | 55-67 | Lost 6 |
| » W: Storm Davis (7-8) L: David West (6-8) | Seventh | 22 out |
| Tuesday, August 21 |
| » Lost to Royals (60-62), 8-7 | Royals Stadium (1-4) | 55-68 | Lost 7 |
| » W: Steve Crawford (5-2) L: Paul Abbott (0-1) S: Jeff Montgomery (18) | Sixth | 22 out |
| » Major-league debuts: Jim Campbell (Royals) Paul Abbott (Twins) |
| Wednesday, August 22 |
| » Lost to Royals (61-62), 6-2 | Royals Stadium (1-5) | 55-69 | Lost 8 |
| » W: Tom Gordon (9-9) L: Scott Erickson (3-4) | Sixth | 23 out |
| Friday, August 24 |
| » Lost to Rangers (65-60), 2-0 | Arlington Stadium (0-4) | 55-70 | Lost 9 |
| » W: John Barfield (3-0) L: Mark Guthrie (4-7) S: Brad Arnsberg (5) | Sixth | 24 out |
| Saturday, August 25 |
| » Defeated Rangers (65-61), 8-5 | Arlington Stadium (1-4) | 56-70 | |
| » W: David West (7-8) L: Gary Mielke (0-3) S: Rick Aguilera (26) | Sixth | 23 out |
| Sunday, August 26 |
| » Lost to Rangers (66-61), 1-0 | Arlington Stadium (1-5) | 56-71 | |
| » W: Bobby Witt (13-8) L: Terry Leach (2-5) | Seventh | 23 out |
| Monday, August 27 |
| » Defeated White Sox (73-53), 7-0 | Hubert H. Humphrey Metrodome (30-33) | 57-71 | |
| » W: Allan Anderson (6-16) L: Melido Perez (11-12) | Seventh | 22½ out |
| Tuesday, August 28 |
| » Defeated White Sox (73-54), 12-6 | Hubert H. Humphrey Metrodome (31-33) | 58-71 | Won 2 |
| » W: Tim Drummond (2-4) L: Adam Peterson (2-5) S: Gary Wayne (1) | Seventh | 22½ out |
| Wednesday, August 29 |
| » Defeated White Sox (73-55), 6-1 | Hubert H. Humphrey Metrodome (32-33) | 59-71 | Won 3 |
| » W: Mark Guthrie (5-7) L: Wayne Edwards (3-3) | Seventh | 21½ out |
| Thursday, August 30 |
| » Lost to White Sox (74-55), 4-3 | Hubert H. Humphrey Metrodome (32-34) | 59-72 | |
| » W: Jack McDowell (11-6) L: David West (7-9) S: Bobby Thigpen (44) | Seventh | 22½ out |
| Friday, August 31 |
| » Lost to Tigers (63-69), 12-6 | Hubert H. Humphrey Metrodome (32-35) | 59-73 | Lost 2 |
| » W: Clay Parker (3-1) L: Paul Abbott (0-2) | Seventh | 23½ out |
| Saturday, September 1 |
| » Lost to Tigers (64-69), 9-5 | Hubert H. Humphrey Metrodome (32-36) | 59-74 | Lost 3 |
| » W: Randy Nosek (1-0) L: Allan Anderson (6-17) S: Mike Henneman (19) | Seventh | 23½ out |
| » Major-league debuts: Pedro Munoz (Twins) |
| Sunday, September 2 |
| » Defeated Tigers (64-70), 4-3 | Hubert H. Humphrey Metrodome (33-36) | 60-74 | |
| » W: Scott Erickson (4-4) L: Jack Morris (11-16) S: Rick Aguilera (27) | Seventh | 23½ out |
| Monday, September 3 |
| » Defeated Brewers (63-70), 6-0 | County Stadium (3-0) | 61-74 | Won 2 |
| » W: Mark Guthrie (6-7) L: Mark Knudson (10-8) | Seventh | 23 out |
| » Defeated Brewers (63-71), 9-5 | County Stadium (4-0) | 62-74 | Won 3 |
| » W: Rick Aguilera (5-3) L: Dan Plesac (3-7) | Seventh | 23 out |
| » Major-league debuts: Tim McIntosh (Brewers) Scott Leius (Twins) |
| Tuesday, September 4 |
| » Defeated Brewers (63-72), 7-1 | County Stadium (5-0) | 63-74 | Won 4 |
| » W: Tim Drummond (3-4) L: Tom Edens (3-2) | Sixth | 23 out |
| Wednesday, September 5 |
| » Lost to Brewers (64-72), 7-4 | County Stadium (5-1) | 63-75 | |
| » W: Ron Robinson (11-5) L: Gary Wayne (0-1) | Seventh | 24 out |
| Friday, September 7 |
| » Defeated Indians (61-77), 2-0 | Hubert H. Humphrey Metrodome (34-36) | 64-75 | |
| » W: Allan Anderson (7-17) L: Bud Black (10-10) S: Rick Aguilera (28) | Seventh | 24 out |
| Saturday, September 8 |
| » Defeated Indians (61-78), 6-1 | Hubert H. Humphrey Metrodome (35-36) | 65-75 | Won 2 |
| » W: Scott Erickson (5-4) L: Mike Walker (1-6) | Seventh | 24 out |
| Sunday, September 9 |
| » Lost to Indians (62-78), 12-9 | Hubert H. Humphrey Metrodome (35-37) | 65-76 | |
| » W: Steve Olin (3-4) L: Jack Savage (0-2) | Sixth | 25 out |
| » Major-league debuts: Larry Casian (Twins) |
| Monday, September 10 |
| » Lost to Angels (70-71), 3-1 | Anaheim Stadium (1-4) | 65-77 | Lost 2 |
| » W: Jim Abbott (10-12) L: Paul Abbott (0-3) S: Bryan Harvey (21) | Sixth | 25 out |
| Tuesday, September 11 |
| » Lost to Angels (71-71), 9-0 | Anaheim Stadium (1-5) | 65-78 | Lost 3 |
| » W: Mark Langston (9-16) L: Kevin Tapani (11-7) | Seventh | 26 out |
| Wednesday, September 12 |
| » Lost to Angels (72-71), 8-6 | Anaheim Stadium (1-6) | 65-79 | Lost 4 |
| » W: Joe Grahe (2-3) L: Tim Drummond (3-5) S: Bryan Harvey (22) | Seventh | 27 out |
| Thursday, September 13 |
| » Defeated Athletics (91-52), 3-1 | Oakland-Alameda County Stadium (2-2) | 66-79 | |
| » W: Juan Berenguer (8-3) L: Gene Nelson (3-3) | Seventh | 26 out |
| Friday, September 14 |
| » Lost to Athletics (92-52), 9-1 | Oakland-Alameda County Stadium (2-3) | 66-80 | |
| » W: Dave Stewart (20-10) L: Mark Guthrie (6-8) | Seventh | 27 out |
| Saturday, September 15 |
| » Lost to Athletics (93-52), 4-1 | Oakland-Alameda County Stadium (2-4) | 66-81 | Lost 2 |
| » W: Bob Welch (24-6) L: Paul Abbott (0-4) S: Dennis Eckersley (43) | Seventh | 28 out |
| » Major-league debuts: Steve Chitren (Athletics) |
| Sunday, September 16 |
| » Lost to Athletics (94-52), 5-4 | Oakland-Alameda County Stadium (2-5) | 66-82 | Lost 3 |
| » W: Dennis Eckersley (4-2) L: Juan Berenguer (8-4) | Seventh | 29 out |
| Monday, September 17 |
| » Lost to Royals (69-78), 1-0 | Hubert H. Humphrey Metrodome (35-38) | 66-83 | Lost 4 |
| » W: Steve Farr (11-7) L: Larry Casian (0-1) S: Jeff Montgomery (20) | Seventh | 29 out |
| » Major-league debuts: Sean Berry (Royals) |
| Tuesday, September 18 |
| » Defeated Royals (69-79), 10-4 | Hubert H. Humphrey Metrodome (36-38) | 67-83 | |
| » W: Scott Erickson (6-4) L: Tom Gordon (11-11) | Seventh | 28 out |
| » Major-league debuts: Rich Garces (Twins) Brent Mayne and Daryl Smith (Royals) |
| Wednesday, September 19 |
| » Defeated Royals (69-80), 1-0 | Hubert H. Humphrey Metrodome (37-38) | 68-83 | Won 2 |
| » W: Gary Wayne (1-1) L: Jeff Montgomery (6-4) | Seventh | 28 out |
| Friday, September 21 |
| » Lost to Rangers (80-70), 2-1 | Hubert H. Humphrey Metrodome (37-39) | 68-84 | |
| » W: Bobby Witt (17-9) L: Juan Berenguer (8-5) | Seventh | 29 out |
| Saturday, September 22 |
| » Defeated Rangers (80-71), 2-0 | Hubert H. Humphrey Metrodome (38-39) | 69-84 | |
| » W: Larry Casian (1-1) L: Scott Chiamparino (0-2) S: Rich Garces (1) | Seventh | 29 out |
| Sunday, September 23 |
| » Defeated Rangers (80-72), 6-4 | Hubert H. Humphrey Metrodome (39-39) | 70-84 | Won 2 |
| » W: Scott Erickson (7-4) L: Charlie Hough (12-11) S: Rick Aguilera (29) | Seventh | 28 out |
| Tuesday, September 25 |
| » Defeated White Sox (89-65), 4-3 | Comiskey Park I (3-2) | 71-84 | Won 3 |
| » W: Mark Guthrie (7-8) L: Jack McDowell (13-9) S: Rick Aguilera (30) | Seventh | 27½ out |
| Wednesday, September 26 |
| » Lost to White Sox (90-65), 3-1 | Comiskey Park I (3-3) | 71-85 | |
| » W: Greg Hibbard (14-9) L: Kevin Tapani (11-8) S: Bobby Thigpen (54) | Seventh | 28½ out |
| Friday, September 28 |
| » Lost to Tigers (76-81), 3-1 | Tiger Stadium (3-1) | 71-86 | Lost 2 |
| » W: Jack Morris (14-18) L: Allan Anderson (7-18) S: Mike Henneman (22) | Seventh | 29 out |
| Saturday, September 29 |
| » Defeated Tigers (76-82), 2-0 | Tiger Stadium (4-1) | 72-86 | |
| » W: Scott Erickson (8-4) L: Scott Aldred (1-2) S: Rick Aguilera (31) | Seventh | 29 out |
| Sunday, September 30 |
| » Lost to Tigers (77-82), 1-0 | Tiger Stadium (4-2) | 72-87 | |
| » W: Walt Terrell (8-11) L: Mark Guthrie (7-9) S: Jerry Don Gleaton (12) | Seventh | 30 out |
| Monday, October 1 |
| » Defeated Mariners (76-84), 7-5 | Hubert H. Humphrey Metrodome (40-39) | 73-87 | |
| » W: Kevin Tapani (12-8) L: Russ Swan (2-4) S: Rich Garces (2) | Seventh | 29 out |
| Tuesday, October 2 |
| » Lost to Mariners (77-84), 3-0 | Hubert H. Humphrey Metrodome (40-40) | 73-88 | |
| » W: Erik Hanson (18-9) L: Paul Abbott (0-5) | Seventh | 30 out |
| Wednesday, October 3 |
| » Defeated Mariners (77-85), 7-4 | Hubert H. Humphrey Metrodome (41-40) | 74-88 | |
| » W: Larry Casian (2-1) L: Randy Johnson (14-11) S: Rick Aguilera (32) | Seventh | 29 out |
Game information provided by Retrosheet (www.retrosheet.org) |