| Wednesday, March 28 |
| Former Tiger Johnny Neun dies in Baltimore, MD at the age of 90. |
| Monday, April 9 |
| » Lost to Red Sox (1-0), 5-2 | Fenway Park (0-1) | 0-1 | |
| » W: Roger Clemens (1-0) L: Jack Morris (0-1) S: Lee Smith (1) | Third | 1 out |
| Tuesday, April 10 |
| » Lost to Red Sox (2-0), 4-2 | Fenway Park (0-2) | 0-2 | Lost 2 |
| » W: Mike Boddicker (1-0) L: Kevin Ritz (0-1) S: Lee Smith (2) | Fifth | 2 out |
| Wednesday, April 11 |
| » Lost to Red Sox (3-0), 3-2 | Fenway Park (0-3) | 0-3 | Lost 3 |
| » W: Greg Harris (1-0) L: Jerry Don Gleaton (0-1) | Sixth | 3 out |
| Thursday, April 12 |
| » Defeated Red Sox (3-1), 11-7 | Tiger Stadium (1-0) | 1-3 | |
| » W: Urbano Lugo (1-0) L: Mike Rochford (0-1) | Fifth | 1½ out |
| » Major-league debuts: Dana Kiecker (Red Sox) |
| Friday, April 13 |
| » Defeated Orioles (1-2), 10-6 | Tiger Stadium (2-0) | 2-3 | Won 2 |
| » W: Jack Morris (1-1) L: Joe Price (0-1) | Fourth | 1½ out |
| Saturday, April 14 |
| » Lost to Orioles (2-2), 7-4 | Tiger Stadium (2-1) | 2-4 | |
| » W: Dave Johnson (1-0) L: Kevin Ritz (0-2) S: Gregg Olson (2) | Sixth | 2 out |
| » Major-league debuts: Steve Wapnick (Tigers) |
| Sunday, April 15 |
| » Defeated Orioles (2-3), 6-4 | Tiger Stadium (3-1) | 3-4 | |
| » W: Dan Petry (1-0) L: Jay Aldrich (1-1) S: Mike Henneman (1) | Fourth | 1½ out |
| Tuesday, April 17 |
| » Lost to Yankees (4-1), 4-1 | Tiger Stadium (3-2) | 3-5 | |
| » W: Tim Leary (1-0) L: Frank Tanana (0-1) S: Dave Righetti (3) | Fourth | 2½ out |
| Wednesday, April 18 |
| » Defeated Yankees (4-2), 8-4 | Tiger Stadium (4-2) | 4-5 | |
| » W: Jack Morris (2-1) L: Dave LaPoint (0-1) S: Mike Henneman (2) | Fourth | 1½ out |
| Thursday, April 19 |
| » Lost to Orioles (4-5), 4-2 | Memorial Stadium (0-1) | 4-6 | |
| » W: Dave Johnson (2-0) L: Kevin Ritz (0-3) S: Gregg Olson (4) | Sixth | 2 out |
| Friday, April 20 |
| » Lost to Orioles (5-5), 6-0 | Memorial Stadium (0-2) | 4-7 | Lost 2 |
| » W: Bob Milacki (1-0) L: Jeff Robinson (0-1) | Sixth | 3 out |
| Saturday, April 21 |
| » Defeated Orioles (5-6), 3-2 | Memorial Stadium (1-2) | 5-7 | |
| » W: Urbano Lugo (2-0) L: Jay Aldrich (1-2) S: Mike Henneman (3) | Fifth | 3 out |
| Sunday, April 22 |
| » Lost to Orioles (6-6), 3-2 | Memorial Stadium (1-3) | 5-8 | |
| » W: Gregg Olson (1-0) L: Mike Henneman (0-1) | Sixth | 3 out |
| Monday, April 23 |
| » Defeated Twins (6-8), 6-3 | Hubert H. Humphrey Metrodome (1-0) | 6-8 | |
| » W: Frank Tanana (1-1) L: Roy Smith (0-2) S: Mike Henneman (4) | Sixth | 3 out |
| Tuesday, April 24 |
| » Lost to Twins (7-8), 16-4 | Hubert H. Humphrey Metrodome (1-1) | 6-9 | |
| » W: John Candelaria (1-0) L: Kevin Ritz (0-4) | Seventh | 4 out |
| Wednesday, April 25 |
| » Defeated Twins (7-9), 6-4 | Hubert H. Humphrey Metrodome (2-1) | 7-9 | |
| » W: Jeff Robinson (1-1) L: Kevin Tapani (2-2) S: Mike Henneman (5) | Fifth | 4 out |
| Friday, April 27 |
| » Lost to Brewers (10-5), 9-6 | Tiger Stadium (4-3) | 7-10 | |
| » W: Bill Krueger (1-0) L: Jack Morris (2-2) S: Chuck Crim (2) | Sixth | 4 out |
| Saturday, April 28 |
| » Defeated Brewers (10-6), 13-5 | Tiger Stadium (5-3) | 8-10 | |
| » W: Frank Tanana (2-1) L: Don August (0-2) | Sixth | 3 out |
| Sunday, April 29 |
| » Lost to Brewers (11-6), 6-1 | Tiger Stadium (5-4) | 8-11 | |
| » W: Chris Bosio (3-0) L: Dan Petry (1-1) | Sixth | 4 out |
| Monday, April 30 |
| » Lost to Brewers (12-6), 6-1 | Tiger Stadium (5-5) | 8-12 | Lost 2 |
| » W: Mark Knudson (2-0) L: Jeff Robinson (1-2) | Seventh | 5 out |
| Tuesday, May 1 |
| » Lost to Twins (8-12), 9-5 | Tiger Stadium (5-6) | 8-13 | Lost 3 |
| » W: John Candelaria (2-0) L: Paul Gibson (0-1) | Seventh | 6 out |
| Wednesday, May 2 |
| » Lost to Twins (9-12), 8-2 | Tiger Stadium (5-7) | 8-14 | Lost 4 |
| » W: David West (2-3) L: Jack Morris (2-3) | Seventh | 6½ out |
| Thursday, May 3 |
| » Lost to Twins (10-12), 3-1 | Tiger Stadium (5-8) | 8-15 | Lost 5 |
| » W: Terry Leach (2-0) L: Mike Henneman (0-2) S: Rick Aguilera (5) | Seventh | 7½ out |
| Friday, May 4 |
| » Defeated Blue Jays (13-11), 3-1 | Skydome (1-0) | 9-15 | |
| » W: Dan Petry (2-1) L: Mike Flanagan (2-2) S: Mike Henneman (6) | Seventh | 7 out |
| Saturday, May 5 |
| » Lost to Blue Jays (14-11), 5-1 | Skydome (1-1) | 9-16 | |
| » W: Todd Stottlemyre (4-2) L: Jeff Robinson (1-3) | Seventh | 7 out |
| Sunday, May 6 |
| » Lost to Blue Jays (15-11), 11-7 | Skydome (1-2) | 9-17 | Lost 2 |
| » W: Jimmy Key (3-1) L: Brian DuBois (0-1) | Sixth | 7 out |
| Monday, May 7 |
| » Lost to Brewers (15-8), 5-4 | County Stadium (0-1) | 9-18 | Lost 3 |
| » W: Bill Krueger (2-0) L: Jack Morris (2-4) S: Dan Plesac (5) | Seventh | 8 out |
| Tuesday, May 8 |
| » Lost to Brewers (16-8), 7-5 | County Stadium (0-2) | 9-19 | Lost 4 |
| » W: Paul Mirabella (1-0) L: Frank Tanana (2-2) S: Dan Plesac (6) | Seventh | 9 out |
| Wednesday, May 9 |
| » Defeated Brewers (16-9), 2-1 | County Stadium (1-2) | 10-19 | |
| » W: Dan Petry (3-1) L: Chris Bosio (3-1) S: Mike Henneman (7) | Seventh | 8 out |
| Thursday, May 10 |
| » Defeated Blue Jays (17-13), 10-5 | Tiger Stadium (6-8) | 11-19 | Won 2 |
| » W: Jeff Robinson (2-3) L: Todd Stottlemyre (4-3) | Seventh | 7½ out |
| Friday, May 11 |
| » Lost to Blue Jays (18-13), 4-2 | Tiger Stadium (6-9) | 11-20 | |
| » W: Jimmy Key (4-1) L: Brian DuBois (0-2) S: Tom Henke (3) | Seventh | 8½ out |
| Sunday, May 13 |
| » Lost to Blue Jays (19-13), 6-3 | Tiger Stadium (6-10) | 11-21 | Lost 2 |
| » W: David Wells (1-0) L: Jack Morris (2-5) | Seventh | 8 out |
| Monday, May 14 |
| » Lost to Blue Jays (20-13), 8-3 | Tiger Stadium (6-11) | 11-22 | Lost 3 |
| » W: Duane Ward (1-0) L: Mike Henneman (0-3) | Seventh | 8½ out |
| Tuesday, May 15 |
| » Defeated Rangers (15-17), 3-2 | Arlington Stadium (1-0) | 12-22 | |
| » W: Dan Petry (4-1) L: Kevin Brown (5-2) S: Mike Henneman (8) | Seventh | 8 out |
| Wednesday, May 16 |
| » Defeated Rangers (15-18), 12-0 | Arlington Stadium (2-0) | 13-22 | Won 2 |
| » W: Jeff Robinson (3-3) L: Brian Bohanon (0-2) | Seventh | 7½ out |
| Thursday, May 17 |
| » Defeated Rangers (15-19), 7-5 | Arlington Stadium (3-0) | 14-22 | Won 3 |
| » W: Mike Henneman (1-3) L: Jeff Russell (1-3) | Seventh | 7½ out |
| Friday, May 18 |
| » Defeated White Sox (20-11), 8-2 | Comiskey Park I (1-0) | 15-22 | Won 4 |
| » W: Brian DuBois (1-2) L: Melido Perez (3-3) | Seventh | 7½ out |
| Saturday, May 19 |
| » Defeated White Sox (20-12), 6-4 | Comiskey Park I (2-0) | 16-22 | Won 5 |
| » W: Frank Tanana (3-2) L: Jack McDowell (1-3) S: Mike Henneman (9) | Sixth | 6½ out |
| Sunday, May 20 |
| » Defeated White Sox (20-13), 3-2 | Comiskey Park I (3-0) | 17-22 | Won 6 |
| » W: Edwin Nunez (1-0) L: Wayne Edwards (0-2) S: Mike Henneman (10) | Fifth | 6½ out |
| Monday, May 21 |
| » Defeated Royals (13-23), 11-6 | Tiger Stadium (7-11) | 18-22 | Won 7 |
| » W: Jeff Robinson (4-3) L: Tom Gordon (1-2) S: Jerry Don Gleaton (1) | Fifth | 5½ out |
| Tuesday, May 22 |
| » Lost to Royals (14-23), 9-8 | Tiger Stadium (7-12) | 18-23 | |
| » W: Steve Farr (3-2) L: Jack Morris (2-6) S: Jeff Montgomery (1) | Fifth | 6½ out |
| Wednesday, May 23 |
| » Defeated Rangers (17-23), 5-1 | Tiger Stadium (8-12) | 19-23 | |
| » W: Brian DuBois (2-2) L: Mike Jeffcoat (0-1) S: Paul Gibson (1) | Fifth | 5½ out |
| » Major-league debuts: John Hoover (Rangers) |
| Former Tiger Charlie Keller dies in Frederick, MD at the age of 74. |
| Thursday, May 24 |
| » Lost to Rangers (18-23), 3-2 | Tiger Stadium (8-13) | 19-24 | |
| » W: Charlie Hough (5-2) L: Frank Tanana (3-3) S: Jeff Russell (8) | Fifth | 5½ out |
| Friday, May 25 |
| » Defeated White Sox (23-15), 2-1 | Tiger Stadium (9-13) | 20-24 | |
| » W: Paul Gibson (1-1) L: Greg Hibbard (3-3) S: Mike Henneman (11) | Fifth | 4½ out |
| Saturday, May 26 |
| » Lost to White Sox (24-15), 10-4 | Tiger Stadium (9-14) | 20-25 | |
| » W: Ken Patterson (1-0) L: Jeff Robinson (4-4) | Fifth | 4½ out |
| Sunday, May 27 |
| » Lost to White Sox (25-15), 2-1 | Tiger Stadium (9-15) | 20-26 | Lost 2 |
| » W: Melido Perez (4-4) L: Jack Morris (2-7) S: Bobby Thigpen (14) | Sixth | 4½ out |
| Monday, May 28 |
| » Lost to Royals (18-25), 3-2 | Royals Stadium (0-1) | 20-27 | Lost 3 |
| » W: Bret Saberhagen (4-3) L: Brian DuBois (2-3) | Sixth | 5 out |
| Tuesday, May 29 |
| » Lost to Royals (19-25), 5-3 | Royals Stadium (0-2) | 20-28 | Lost 4 |
| » W: Steve Farr (4-2) L: Mike Henneman (1-4) S: Jeff Montgomery (3) | Sixth | 6 out |
| Wednesday, May 30 |
| » Lost to Royals (20-25), 4-3 | Royals Stadium (0-3) | 20-29 | Lost 5 |
| » W: Luis Aquino (1-0) L: Dan Petry (4-2) S: Jeff Montgomery (4) | Sixth | 6 out |
| Friday, June 1 |
| » Defeated Mariners (23-27), 9-7 | Kingdome (1-0) | 21-29 | |
| » W: Jack Morris (3-7) L: Scott Bankhead (0-2) S: Mike Henneman (12) | Sixth | 5½ out |
| Saturday, June 2 |
| » Lost to Mariners (24-27), 2-0 | Kingdome (1-1) | 21-30 | |
| » W: Randy Johnson (4-3) L: Jeff Robinson (4-5) | Sixth | 6½ out |
| Sunday, June 3 |
| » Defeated Mariners (24-28), 2-0 | Kingdome (2-1) | 22-30 | |
| » W: Frank Tanana (4-3) L: Erik Hanson (5-4) S: Mike Henneman (13) | Sixth | 5½ out |
| Tuesday, June 5 |
| » Defeated Indians (23-26), 6-2 | Cleveland Stadium (1-0) | 23-30 | Won 2 |
| » W: Dan Petry (5-2) L: Tom Candiotti (5-3) S: Edwin Nunez (1) | Sixth | 5½ out |
| Wednesday, June 6 |
| » Defeated Indians (23-27), 6-4 | Cleveland Stadium (2-0) | 24-30 | Won 3 |
| » W: Jack Morris (4-7) L: Greg Swindell (2-5) S: Mike Henneman (14) | Sixth | 5½ out |
| Thursday, June 7 |
| » Defeated Indians (23-28), 8-0 | Cleveland Stadium (3-0) | 25-30 | Won 4 |
| » W: Brian DuBois (3-3) L: Bud Black (4-3) | Fifth | 5½ out |
| » Major-league debuts: Jeff Manto (Indians) |
| Friday, June 8 |
| » Lost to Mariners (27-29), 5-2 | Tiger Stadium (9-16) | 25-31 | |
| » W: Erik Hanson (6-4) L: Frank Tanana (4-4) S: Mike Jackson (2) | Fifth | 6 out |
| » Defeated Mariners (27-30), 6-3 | Tiger Stadium (10-16) | 26-31 | |
| » W: Mike Henneman (2-4) L: Keith Comstock (1-2) | Fifth | 6 out |
| Saturday, June 9 |
| » Lost to Mariners (28-30), 5-2 | Tiger Stadium (10-17) | 26-32 | |
| » W: Russ Swan (1-1) L: Dan Petry (5-3) | Fifth | 7 out |
| Sunday, June 10 |
| » Defeated Mariners (28-31), 4-3 | Tiger Stadium (11-17) | 27-32 | |
| » W: Jack Morris (5-7) L: Brian Holman (7-4) S: Mike Henneman (15) | Fifth | 6 out |
| Tuesday, June 12 |
| » Lost to Indians (26-30), 7-3 | Tiger Stadium (11-18) | 27-33 | |
| » W: Bud Black (5-3) L: Brian DuBois (3-4) | Sixth | 6 out |
| Former Tiger Jim Walkup dies in Duncan, OK at the age of 95. |
| Wednesday, June 13 |
| » Defeated Indians (26-31), 5-4 | Tiger Stadium (12-18) | 28-33 | |
| » W: Mike Henneman (3-4) L: Rudy Seanez (1-1) | Fifth | 6 out |
| Thursday, June 14 |
| » Defeated Indians (26-32), 7-3 | Tiger Stadium (13-18) | 29-33 | Won 2 |
| » W: Frank Tanana (5-4) L: Sergio Valdez (2-3) | Fifth | 6 out |
| Friday, June 15 |
| » Defeated Angels (31-31), 2-1 | Tiger Stadium (14-18) | 30-33 | Won 3 |
| » W: Jerry Don Gleaton (1-1) L: Bryan Harvey (2-2) | Fourth | 6 out |
| Saturday, June 16 |
| » Defeated Angels (31-32), 6-2 | Tiger Stadium (15-18) | 31-33 | Won 4 |
| » W: Jack Morris (6-7) L: Bert Blyleven (6-4) | Third | 6 out |
| Sunday, June 17 |
| » Lost to Angels (32-32), 7-3 | Tiger Stadium (15-19) | 31-34 | |
| » W: Chuck Finley (10-3) L: Brian DuBois (3-5) S: Bryan Harvey (8) | Third | 7 out |
| Monday, June 18 |
| » Defeated Athletics (42-21), 7-2 | Tiger Stadium (16-19) | 32-34 | |
| » W: Jeff Robinson (5-5) L: Curt Young (3-2) S: Edwin Nunez (2) | Third | 6½ out |
| Tuesday, June 19 |
| » Defeated Athletics (42-22), 7-6 | Tiger Stadium (17-19) | 33-34 | Won 2 |
| » W: Paul Gibson (2-1) L: Dave Stewart (9-5) S: Mike Henneman (16) | Third | 5½ out |
| Wednesday, June 20 |
| » Lost to Athletics (43-22), 12-7 | Tiger Stadium (17-20) | 33-35 | |
| » W: Bob Welch (11-2) L: Dan Petry (5-4) | Third | 6½ out |
| Thursday, June 21 |
| » Lost to Angels (35-33), 6-4 | Anaheim Stadium (0-1) | 33-36 | Lost 2 |
| » W: Bert Blyleven (7-4) L: Jack Morris (6-8) S: Bryan Harvey (10) | Fourth | 6½ out |
| Friday, June 22 |
| » Lost to Angels (36-33), 1-0 | Anaheim Stadium (0-2) | 33-37 | Lost 3 |
| » W: Scott Bailes (2-0) L: Paul Gibson (2-2) | Fourth | 6½ out |
| Saturday, June 23 |
| » Defeated Angels (36-34), 9-4 | Anaheim Stadium (1-2) | 34-37 | |
| » W: Jeff Robinson (6-5) L: Jim Abbott (4-6) | Fourth | 6½ out |
| Sunday, June 24 |
| » Lost to Angels (37-34), 10-2 | Anaheim Stadium (1-3) | 34-38 | |
| » W: Kirk McCaskill (6-3) L: Frank Tanana (5-5) | Fourth | 7½ out |
| Monday, June 25 |
| » Lost to Athletics (44-25), 4-3 | Oakland-Alameda County Stadium (0-1) | 34-39 | Lost 2 |
| » W: Bob Welch (12-2) L: Dan Petry (5-5) S: Dennis Eckersley (23) | Fifth | 8 out |
| Tuesday, June 26 |
| » Lost to Athletics (45-25), 3-2 | Oakland-Alameda County Stadium (0-2) | 34-40 | Lost 3 |
| » W: Scott Sanderson (9-4) L: Jack Morris (6-9) S: Dennis Eckersley (24) | Fifth | 9 out |
| Wednesday, June 27 |
| » Defeated Athletics (45-26), 5-4 | Oakland-Alameda County Stadium (1-2) | 35-40 | |
| » W: Mike Henneman (4-4) L: Todd Burns (2-1) | Fifth | 9 out |
| Friday, June 29 |
| » Lost to Royals (31-41), 3-2 | Royals Stadium (0-4) | 35-41 | |
| » W: Steve Crawford (1-1) L: Jeff Robinson (6-6) S: Jeff Montgomery (7) | Fourth | 9½ out |
| Saturday, June 30 |
| » Defeated Royals (31-42), 5-3 | Royals Stadium (1-4) | 36-41 | |
| » W: Edwin Nunez (2-0) L: Storm Davis (2-6) S: Mike Henneman (17) | Fourth | 8½ out |
| Sunday, July 1 |
| » Defeated Royals (31-43), 9-4 | Royals Stadium (2-4) | 37-41 | Won 2 |
| » W: Jack Morris (7-9) L: Tom Gordon (5-5) S: Paul Gibson (2) | Fourth | 8½ out |
| Monday, July 2 |
| » Lost to White Sox (47-26), 5-4 | Comiskey Park I (3-1) | 37-42 | |
| » W: Bobby Thigpen (4-2) L: Mike Henneman (4-5) | Fourth | 9½ out |
| Tuesday, July 3 |
| » Defeated White Sox (47-27), 13-7 | Comiskey Park I (4-1) | 38-42 | |
| » W: Edwin Nunez (3-0) L: Eric King (8-2) S: Jerry Don Gleaton (2) | Fourth | 8½ out |
| Wednesday, July 4 |
| » Defeated White Sox (47-28), 10-7 | Comiskey Park I (5-1) | 39-42 | Won 2 |
| » W: Lance McCullers (2-0) L: Ken Patterson (1-1) | Fourth | 8½ out |
| Thursday, July 5 |
| » Lost to Royals (35-43), 15-3 | Tiger Stadium (17-21) | 39-43 | |
| » W: Luis Aquino (3-0) L: Dan Petry (5-6) | Fourth | 8½ out |
| Friday, July 6 |
| » Defeated Royals (35-44), 4-0 | Tiger Stadium (18-21) | 40-43 | |
| » W: Jack Morris (8-9) L: Tom Gordon (5-6) | Fourth | 7½ out |
| Saturday, July 7 |
| » Lost to Royals (36-44), 4-0 | Tiger Stadium (18-22) | 40-44 | |
| » W: Kevin Appier (4-3) L: Frank Tanana (5-6) | Fourth | 7½ out |
| » Major-league debuts: Travis Fryman (Tigers) |
| Sunday, July 8 |
| » Defeated Royals (36-45), 10-4 | Tiger Stadium (19-22) | 41-44 | |
| » W: Dan Petry (6-6) L: Mark Davis (1-6) | Fourth | 6½ out |
| Thursday, July 12 |
| » Lost to Rangers (41-44), 11-1 | Tiger Stadium (19-23) | 41-45 | |
| » W: Kevin Brown (11-6) L: Jack Morris (8-10) | Fourth | 7 out |
| Friday, July 13 |
| » Lost to Rangers (42-44), 7-6 | Tiger Stadium (19-24) | 41-46 | Lost 2 |
| » W: Bobby Witt (6-8) L: Jerry Don Gleaton (1-2) S: Kenny Rogers (8) | Fourth | 7 out |
| Saturday, July 14 |
| » Lost to Rangers (43-44), 5-3 | Tiger Stadium (19-25) | 41-47 | Lost 3 |
| » W: Nolan Ryan (9-4) L: Jeff Robinson (6-7) S: Brad Arnsberg (1) | Fourth | 7½ out |
| Sunday, July 15 |
| » Defeated Rangers (43-45), 3-2 | Tiger Stadium (20-25) | 42-47 | |
| » W: Steve Searcy (1-0) L: Mike Jeffcoat (3-4) S: Mike Henneman (18) | Fourth | 6½ out |
| Monday, July 16 |
| » Defeated White Sox (52-32), 5-4 | Tiger Stadium (21-25) | 43-47 | Won 2 |
| » W: Mike Henneman (5-5) L: Donn Pall (1-4) | Fourth | 6 out |
| Tuesday, July 17 |
| » Lost to White Sox (53-32), 7-3 | Tiger Stadium (21-26) | 43-48 | |
| » W: Melido Perez (9-7) L: Jack Morris (8-11) | Fourth | 6½ out |
| Wednesday, July 18 |
| » Lost to White Sox (54-32), 7-5 | Tiger Stadium (21-27) | 43-49 | Lost 2 |
| » W: Donn Pall (2-4) L: Mike Henneman (5-6) S: Bobby Thigpen (31) | Fifth | 7½ out |
| Thursday, July 19 |
| » Defeated Red Sox (49-41), 1-0 | Tiger Stadium (22-27) | 44-49 | |
| » W: Jeff Robinson (7-7) L: Greg Harris (7-4) S: Jerry Don Gleaton (3) | Fifth | 6½ out |
| Friday, July 20 |
| » Lost to Rangers (45-47), 5-3 | Arlington Stadium (3-1) | 44-50 | |
| » W: Nolan Ryan (10-4) L: Steve Searcy (1-1) S: Kenny Rogers (9) | Fifth | 7 out |
| Saturday, July 21 |
| » Defeated Rangers (45-48), 8-1 | Arlington Stadium (4-1) | 45-50 | |
| » W: Dan Petry (7-6) L: Mike Jeffcoat (3-5) | Fifth | 6½ out |
| Sunday, July 22 |
| » Lost to Rangers (46-48), 5-3 | Arlington Stadium (4-2) | 45-51 | |
| » W: Brad Arnsberg (3-1) L: Jack Morris (8-12) S: Kenny Rogers (10) | Fifth | 6½ out |
| Monday, July 23 |
| » Lost to Orioles (47-48), 13-3 | Tiger Stadium (22-28) | 45-52 | Lost 2 |
| » W: Dave Johnson (9-6) L: Frank Tanana (5-7) | Fifth | 7 out |
| Tuesday, July 24 |
| » Defeated Orioles (47-49), 8-2 | Tiger Stadium (23-28) | 46-52 | |
| » W: Jeff Robinson (8-7) L: John Mitchell (2-3) | Fifth | 6 out |
| Wednesday, July 25 |
| » Defeated Orioles (47-50), 4-3 | Tiger Stadium (24-28) | 47-52 | Won 2 |
| » W: Mike Henneman (6-6) L: Bob Milacki (4-7) S: Jerry Don Gleaton (4) | Fourth | 5 out |
| Thursday, July 26 |
| » Defeated Red Sox (51-47), 10-4 | Tiger Stadium (25-28) | 48-52 | Won 3 |
| » W: Dan Petry (8-6) L: Wes Gardner (2-6) | Fourth | 5 out |
| Friday, July 27 |
| » Lost to Red Sox (52-47), 1-0 | Tiger Stadium (25-29) | 48-53 | |
| » W: Tom Bolton (4-1) L: Jack Morris (8-13) S: Rob Murphy (5) | Fourth | 6 out |
| Saturday, July 28 |
| » Defeated Red Sox (52-48), 17-9 | Tiger Stadium (26-29) | 49-53 | |
| » W: Paul Gibson (3-2) L: Dennis Lamp (3-3) | Fourth | 5 out |
| Sunday, July 29 |
| » Lost to Red Sox (53-48), 13-3 | Tiger Stadium (26-30) | 49-54 | |
| » W: Greg Harris (8-4) L: Jeff Robinson (8-8) | Fourth | 6 out |
| Monday, July 30 |
| » Lost to Yankees (39-61), 6-2 | Yankee Stadium (0-1) | 49-55 | Lost 2 |
| » W: Dave LaPoint (6-7) L: Steve Searcy (1-2) | Fourth | 7 out |
| Tuesday, July 31 |
| » Lost to Yankees (40-61), 10-4 | Yankee Stadium (0-2) | 49-56 | Lost 3 |
| » W: Mark Leiter (1-1) L: Dan Petry (8-7) | Third | 7 out |
| Wednesday, August 1 |
| » Defeated Yankees (40-62), 15-4 | Yankee Stadium (1-2) | 50-56 | |
| » W: Jack Morris (9-13) L: Andy Hawkins (2-9) | Third | 7 out |
| Thursday, August 2 |
| » Defeated Yankees (40-63), 6-5 | Yankee Stadium (2-2) | 51-56 | Won 2 |
| » W: Clay Parker (2-1) L: Alan Mills (1-4) S: Frank Tanana (1) | Fourth | 6½ out |
| Friday, August 3 |
| » Lost to Red Sox (57-48), 14-5 | Fenway Park (0-4) | 51-57 | |
| » W: Greg Harris (9-4) L: Jeff Robinson (8-9) | Fourth | 7½ out |
| Saturday, August 4 |
| » Lost to Red Sox (58-48), 3-1 | Fenway Park (0-5) | 51-58 | Lost 2 |
| » W: Roger Clemens (15-5) L: Steve Searcy (1-3) S: Rob Murphy (6) | Fourth | 8½ out |
| Sunday, August 5 |
| » Defeated Red Sox (58-49), 7-2 | Fenway Park (1-5) | 52-58 | |
| » W: Dan Petry (9-7) L: Mike Boddicker (11-7) S: Jerry Don Gleaton (5) | Fourth | 7½ out |
| Monday, August 6 |
| » Major-league debuts: Randy Tomlin (Pirates) |
| Tuesday, August 7 |
| » Lost to Blue Jays (58-52), 11-5 | Skydome (1-3) | 52-59 | |
| » W: Jimmy Key (7-5) L: Jack Morris (9-14) | Fourth | 8½ out |
| Wednesday, August 8 |
| » Lost to Blue Jays (59-52), 8-3 | Skydome (1-4) | 52-60 | Lost 2 |
| » W: David Wells (8-3) L: Walt Terrell (2-8) | Fifth | 8½ out |
| Thursday, August 9 |
| » Defeated Blue Jays (59-53), 5-4 | Skydome (2-4) | 53-60 | |
| » W: Jeff Robinson (9-9) L: Todd Stottlemyre (10-13) S: Jerry Don Gleaton (6) | Fourth | 8½ out |
| Friday, August 10 |
| » Lost to Indians (52-60), 5-2 | Cleveland Stadium (3-1) | 53-61 | |
| » W: Mike Walker (1-3) L: Steve Searcy (1-4) S: Doug Jones (30) | Fourth | 8½ out |
| Saturday, August 11 |
| » Lost to Indians (53-60), 13-4 | Cleveland Stadium (3-2) | 53-62 | Lost 2 |
| » W: Greg Swindell (8-7) L: Dan Petry (9-8) S: Colby Ward (1) | Fifth | 9½ out |
| Sunday, August 12 |
| » Lost to Indians (54-60), 9-5 | Cleveland Stadium (3-3) | 53-63 | Lost 3 |
| » W: Tom Candiotti (12-7) L: Jack Morris (9-15) S: Doug Jones (31) | Fifth | 10½ out |
| Monday, August 13 |
| » Defeated Indians (54-61), 6-5 | Cleveland Stadium (4-3) | 54-63 | |
| » W: Walt Terrell (3-8) L: Jeff Shaw (2-3) S: Jerry Don Gleaton (7) | Fifth | 9½ out |
| » Major-league debuts: Efrain Valdez (Indians) |
| Tuesday, August 14 |
| » Lost to Brewers (49-65), 7-6 | Tiger Stadium (26-31) | 54-64 | |
| » W: Chuck Crim (3-4) L: Jerry Don Gleaton (1-3) S: Dan Plesac (17) | Fifth | 10½ out |
| Wednesday, August 15 |
| » Lost to Brewers (50-65), 7-3 | Tiger Stadium (26-32) | 54-65 | Lost 2 |
| » W: Paul Mirabella (4-2) L: Steve Searcy (1-5) S: Dan Plesac (18) | Fifth | 10½ out |
| Thursday, August 16 |
| » Lost to Brewers (51-65), 8-4 | Tiger Stadium (26-33) | 54-66 | Lost 3 |
| » W: Ron Robinson (9-5) L: Dan Petry (9-9) S: Dan Plesac (19) | Fifth | 11 out |
| Friday, August 17 |
| » Defeated Indians (56-63), 3-0 | Tiger Stadium (27-33) | 55-66 | |
| » W: Jack Morris (10-15) L: Tom Candiotti (12-8) | Fifth | 10 out |
| Saturday, August 18 |
| » Defeated Indians (56-64), 6-3 | Tiger Stadium (28-33) | 56-66 | Won 2 |
| » W: Walt Terrell (4-8) L: Jeff Shaw (2-4) S: Edwin Nunez (3) | Fifth | 9 out |
| Monday, August 20 |
| » Lost to Angels (61-61), 5-3 | Tiger Stadium (28-34) | 56-67 | |
| » W: Mark Langston (7-15) L: Paul Gibson (3-3) S: Bryan Harvey (16) | Fifth | 10½ out |
| Tuesday, August 21 |
| » Defeated Angels (61-62), 6-2 | Tiger Stadium (29-34) | 57-67 | |
| » W: Dan Petry (10-9) L: Joe Grahe (0-1) S: Edwin Nunez (4) | Fourth | 9½ out |
| Wednesday, August 22 |
| » Defeated Angels (61-63), 7-4 | Tiger Stadium (30-34) | 58-67 | Won 2 |
| » W: Jack Morris (11-15) L: Chuck Finley (16-6) S: Jerry Don Gleaton (8) | Fourth | 9½ out |
| Friday, August 24 |
| » Lost to Athletics (79-46), 6-4 | Tiger Stadium (30-35) | 58-68 | |
| » W: Scott Sanderson (13-8) L: Walt Terrell (4-9) S: Dennis Eckersley (39) | Fifth | 10 out |
| Saturday, August 25 |
| » Defeated Athletics (79-47), 14-4 | Tiger Stadium (31-35) | 59-68 | |
| » W: Frank Tanana (6-7) L: Dave Stewart (17-10) | Fourth | 10 out |
| Sunday, August 26 |
| » Defeated Athletics (79-48), 7-3 | Tiger Stadium (32-35) | 60-68 | Won 2 |
| » W: Jeff Robinson (10-9) L: Bob Welch (21-5) | Fourth | 10 out |
| Tuesday, August 28 |
| » Lost to Mariners (63-66), 4-3 | Kingdome (2-2) | 60-69 | |
| » W: Keith Comstock (6-3) L: Paul Gibson (3-4) | Fifth | 11½ out |
| Wednesday, August 29 |
| » Defeated Mariners (63-67), 4-2 | Kingdome (3-2) | 61-69 | |
| » W: Walt Terrell (5-9) L: Matt Young (6-14) S: Jerry Don Gleaton (9) | Third | 11½ out |
| Thursday, August 30 |
| » Defeated Mariners (63-68), 3-2 | Kingdome (4-2) | 62-69 | Won 2 |
| » W: Mike Henneman (7-6) L: Mike Jackson (5-6) | Third | 11½ out |
| Friday, August 31 |
| » Defeated Twins (59-73), 12-6 | Hubert H. Humphrey Metrodome (3-1) | 63-69 | Won 3 |
| » W: Clay Parker (3-1) L: Paul Abbott (0-2) | Third | 11½ out |
| Saturday, September 1 |
| » Defeated Twins (59-74), 9-5 | Hubert H. Humphrey Metrodome (4-1) | 64-69 | Won 4 |
| » W: Randy Nosek (1-0) L: Allan Anderson (6-17) S: Mike Henneman (19) | Third | 11½ out |
| » Major-league debuts: Pedro Munoz (Twins) |
| Sunday, September 2 |
| » Lost to Twins (60-74), 4-3 | Hubert H. Humphrey Metrodome (4-2) | 64-70 | |
| » W: Scott Erickson (4-4) L: Jack Morris (11-16) S: Rick Aguilera (27) | Third | 12½ out |
| Monday, September 3 |
| » Defeated Blue Jays (70-65), 5-0 | Tiger Stadium (33-35) | 65-70 | |
| » W: Walt Terrell (6-9) L: Jimmy Key (9-7) | Third | 11½ out |
| Tuesday, September 4 |
| » Defeated Blue Jays (70-66), 3-1 | Tiger Stadium (34-35) | 66-70 | Won 2 |
| » W: Paul Gibson (4-4) L: Duane Ward (2-8) S: Mike Henneman (20) | Third | 10½ out |
| » Major-league debuts: Tom Quinlan (Blue Jays) |
| Wednesday, September 5 |
| » Lost to Blue Jays (71-66), 7-3 | Tiger Stadium (34-36) | 66-71 | |
| » W: David Wells (10-4) L: Clay Parker (3-2) | Third | 10½ out |
| Thursday, September 6 |
| » Lost to Indians (61-76), 6-0 | Tiger Stadium (34-37) | 66-72 | Lost 2 |
| » W: Tom Candiotti (14-10) L: Randy Nosek (1-1) | Third | 11 out |
| » Major-league debuts: Milt Cuyler (Tigers) |
| Friday, September 7 |
| » Lost to Brewers (65-72), 6-5 | County Stadium (1-3) | 66-73 | Lost 3 |
| » W: Teddy Higuera (10-6) L: Jack Morris (11-17) S: Chuck Crim (10) | Third | 12 out |
| » Major-league debuts: Rich Rowland (Tigers) |
| Saturday, September 8 |
| » Lost to Brewers (66-72), 5-2 | County Stadium (1-4) | 66-74 | Lost 4 |
| » W: Jaime Navarro (7-5) L: Walt Terrell (6-10) S: Julio Machado (1) | Fourth | 13 out |
| Sunday, September 9 |
| » Defeated Brewers (66-73), 5-0 | County Stadium (2-4) | 67-74 | |
| » W: Scott Aldred (1-0) L: Bill Krueger (5-8) S: Edwin Nunez (5) | Fourth | 12 out |
| » Major-league debuts: Narciso Elvira (Brewers) Scott Aldred (Tigers) |
| Former Tiger Doc Cramer dies in Manahawkin, NJ at the age of 86. |
| Monday, September 10 |
| » Defeated Orioles (63-76), 8-0 | Memorial Stadium (2-3) | 68-74 | Won 2 |
| » W: Frank Tanana (7-7) L: Pete Harnisch (10-11) | Third | 11½ out |
| Tuesday, September 11 |
| » Defeated Orioles (63-77), 2-1 | Memorial Stadium (3-3) | 69-74 | Won 3 |
| » W: Paul Gibson (5-4) L: Curt Schilling (1-1) S: Jerry Don Gleaton (10) | Third | 10½ out |
| Wednesday, September 12 |
| » Lost to Orioles (64-77), 2-1 | Memorial Stadium (3-4) | 69-75 | |
| » W: Ben McDonald (7-4) L: Jack Morris (11-18) | |
