| Monday, April 9 |
| » Defeated Royals (0-1), 7-6 | Royals Stadium (1-0) | 1-0 | |
| » W: Jay Aldrich (1-0) L: Jeff Montgomery (0-1) S: Gregg Olson (1) | First | -- |
| Wednesday, April 11 |
| » Lost to Royals (1-1), 2-1 | Royals Stadium (1-1) | 1-1 | |
| » W: Mark Gubicza (1-0) L: Jeff Ballard (0-1) S: Mark Davis (1) | Third | 1½ out |
| Friday, April 13 |
| » Lost to Tigers (2-3), 10-6 | Tiger Stadium (0-1) | 1-2 | Lost 2 |
| » W: Jack Morris (1-1) L: Joe Price (0-1) | Fifth | 1½ out |
| Saturday, April 14 |
| » Defeated Tigers (2-4), 7-4 | Tiger Stadium (1-1) | 2-2 | |
| » W: Dave Johnson (1-0) L: Kevin Ritz (0-2) S: Gregg Olson (2) | Third | 1 out |
| » Major-league debuts: Steve Wapnick (Tigers) |
| Sunday, April 15 |
| » Lost to Tigers (3-4), 6-4 | Tiger Stadium (1-2) | 2-3 | |
| » W: Dan Petry (1-0) L: Jay Aldrich (1-1) S: Mike Henneman (1) | Fifth | 1½ out |
| Monday, April 16 |
| » Lost to Blue Jays (5-3), 4-2 | Skydome (0-1) | 2-4 | Lost 2 |
| » W: John Cerutti (1-1) L: Jay Tibbs (0-1) S: Tom Henke (1) | Sixth | 2 out |
| Tuesday, April 17 |
| » Lost to Blue Jays (6-3), 8-2 | Skydome (0-2) | 2-5 | Lost 3 |
| » W: Mike Flanagan (2-0) L: Jeff Ballard (0-2) | Sixth | 3 out |
| Wednesday, April 18 |
| » Defeated Blue Jays (6-4), 8-5 | Skydome (1-2) | 3-5 | |
| » W: Pete Harnisch (1-0) L: Frank Wills (0-1) S: Gregg Olson (3) | Sixth | 2 out |
| Thursday, April 19 |
| » Defeated Tigers (4-6), 4-2 | Memorial Stadium (1-0) | 4-5 | Won 2 |
| » W: Dave Johnson (2-0) L: Kevin Ritz (0-3) S: Gregg Olson (4) | Fifth | 1½ out |
| Friday, April 20 |
| » Defeated Tigers (4-7), 6-0 | Memorial Stadium (2-0) | 5-5 | Won 3 |
| » W: Bob Milacki (1-0) L: Jeff Robinson (0-1) | Fourth | 1½ out |
| Saturday, April 21 |
| » Lost to Tigers (5-7), 3-2 | Memorial Stadium (2-1) | 5-6 | |
| » W: Urbano Lugo (2-0) L: Jay Aldrich (1-2) S: Mike Henneman (3) | Third | 2½ out |
| Sunday, April 22 |
| » Defeated Tigers (5-8), 3-2 | Memorial Stadium (3-1) | 6-6 | |
| » W: Gregg Olson (1-0) L: Mike Henneman (0-1) | Fourth | 1½ out |
| Monday, April 23 |
| » Defeated Royals (5-7), 8-5 | Memorial Stadium (4-1) | 7-6 | Won 2 |
| » W: Pete Harnisch (2-0) L: Storm Davis (1-2) S: Jay Aldrich (1) | Third | 1½ out |
| Tuesday, April 24 |
| » Lost to Athletics (10-3), 7-1 | Memorial Stadium (4-2) | 7-7 | |
| » W: Dave Stewart (4-0) L: Dave Johnson (2-1) | Fourth | 2½ out |
| Wednesday, April 25 |
| » Lost to Athletics (11-3), 4-3 | Memorial Stadium (4-3) | 7-8 | Lost 2 |
| » W: Gene Nelson (1-0) L: Kevin Hickey (0-1) S: Dennis Eckersley (5) | Fourth | 3½ out |
| Thursday, April 26 |
| » Lost to Athletics (12-3), 6-4 | Memorial Stadium (4-4) | 7-9 | Lost 3 |
| » W: Mike Moore (1-1) L: Jay Tibbs (0-2) S: Dennis Eckersley (6) | Fourth | 3½ out |
| Friday, April 27 |
| » Lost to Mariners (7-10), 4-3 | Memorial Stadium (4-5) | 7-10 | Lost 4 |
| » W: Erik Hanson (2-0) L: Jeff Ballard (0-3) S: Mike Schooler (4) | Sixth | 4 out |
| Saturday, April 28 |
| » Lost to Mariners (8-10), 4-3 | Memorial Stadium (4-6) | 7-11 | Lost 5 |
| » W: Mike Jackson (1-0) L: Kevin Hickey (0-2) S: Mike Schooler (5) | Seventh | 4 out |
| Sunday, April 29 |
| » Defeated Mariners (8-11), 5-4 | Memorial Stadium (5-6) | 8-11 | |
| » W: Mark Williamson (1-0) L: Mike Jackson (1-1) | Sixth | 4 out |
| Monday, April 30 |
| » Defeated Angels (8-11), 2-1 | Memorial Stadium (6-6) | 9-11 | Won 2 |
| » W: Brian Holton (1-0) L: Mike Witt (0-3) | Fifth | 4 out |
| Tuesday, May 1 |
| » Lost to Angels (9-11), 7-1 | Memorial Stadium (6-7) | 9-12 | |
| » W: Jim Abbott (1-1) L: Jay Tibbs (0-3) | Fifth | 5 out |
| Wednesday, May 2 |
| » Lost to Angels (10-11), 3-0 | Memorial Stadium (6-8) | 9-13 | Lost 2 |
| » W: Bert Blyleven (1-2) L: Jeff Ballard (0-4) S: Mark Eichhorn (5) | Fifth | 5½ out |
| Friday, May 4 |
| » Defeated Mariners (10-14), 9-8 | Kingdome (1-0) | 10-13 | |
| » W: Kevin Hickey (1-2) L: Mike Jackson (1-2) S: Gregg Olson (5) | Fifth | 5½ out |
| Saturday, May 5 |
| » Lost to Mariners (11-14), 5-2 | Kingdome (1-1) | 10-14 | |
| » W: Brian Holman (4-2) L: Dave Johnson (2-2) S: Mike Schooler (7) | Fifth | 5½ out |
| Sunday, May 6 |
| » Lost to Mariners (12-14), 5-4 | Kingdome (1-2) | 10-15 | Lost 2 |
| » W: Bill Swift (1-0) L: Mark Williamson (1-1) S: Mike Schooler (8) | Fifth | 5½ out |
| Monday, May 7 |
| » Defeated Angels (10-16), 6-5 | Anaheim Stadium (1-0) | 11-15 | |
| » W: Jay Tibbs (1-3) L: Mark Eichhorn (0-2) S: Gregg Olson (6) | Fifth | 5½ out |
| Tuesday, May 8 |
| » Lost to Angels (11-16), 6-0 | Anaheim Stadium (1-1) | 11-16 | |
| » W: Chuck Finley (4-2) L: Jeff Ballard (0-5) | Fifth | 6½ out |
| » Major-league debuts: David Segui (Orioles) |
| Wednesday, May 9 |
| » Defeated Angels (11-17), 9-1 | Anaheim Stadium (2-1) | 12-16 | |
| » W: Pete Harnisch (3-0) L: Mark Langston (2-3) | Fifth | 5½ out |
| Friday, May 11 |
| » Lost to Athletics (22-6), 5-0 | Oakland-Alameda County Stadium (0-1) | 12-17 | |
| » W: Bob Welch (4-2) L: Bob Milacki (1-1) | Fifth | 6½ out |
| Saturday, May 12 |
| » Defeated Athletics (22-7), 3-2 | Oakland-Alameda County Stadium (1-1) | 13-17 | |
| » W: Mark Williamson (2-1) L: Gene Nelson (1-2) S: Gregg Olson (7) | Fifth | 5½ out |
| Sunday, May 13 |
| » Defeated Athletics (22-8), 4-1 | Oakland-Alameda County Stadium (2-1) | 14-17 | Won 2 |
| » W: Jay Tibbs (2-3) L: Mike Moore (3-2) S: Gregg Olson (8) | Fifth | 4½ out |
| Tuesday, May 15 |
| » Lost to White Sox (18-10), 3-2 | Comiskey Park I (0-1) | 14-18 | |
| » W: Barry Jones (5-0) L: Pete Harnisch (3-1) S: Bobby Thigpen (9) | Fifth | 5 out |
| Wednesday, May 16 |
| » Lost to White Sox (19-10), 4-2 | Comiskey Park I (0-2) | 14-19 | Lost 2 |
| » W: Jerry Kutzler (2-0) L: Bob Milacki (1-2) S: Bobby Thigpen (10) | Sixth | 5½ out |
| Thursday, May 17 |
| » Lost to White Sox (20-10), 7-3 | Comiskey Park I (0-3) | 14-20 | Lost 3 |
| » W: Barry Jones (6-0) L: Brian Holton (1-1) | Sixth | 6½ out |
| Friday, May 18 |
| » Defeated Rangers (15-20), 13-1 | Memorial Stadium (7-8) | 15-20 | |
| » W: Dave Johnson (3-2) L: Bobby Witt (1-5) | Fifth | 6½ out |
| Saturday, May 19 |
| » Lost to Rangers (16-20), 5-3 | Memorial Stadium (7-9) | 15-21 | |
| » W: Charlie Hough (4-2) L: Jay Tibbs (2-4) S: Jeff Russell (6) | Seventh | 6½ out |
| Sunday, May 20 |
| » Defeated Rangers (16-21), 4-0 | Memorial Stadium (8-9) | 16-21 | |
| » W: Pete Harnisch (4-1) L: Kevin Brown (5-3) S: Gregg Olson (9) | Sixth | 6½ out |
| Monday, May 21 |
| » Lost to Twins (21-16), 7-3 | Memorial Stadium (8-10) | 16-22 | |
| » W: Mark Guthrie (1-0) L: Bob Milacki (1-3) | Sixth | 6½ out |
| Tuesday, May 22 |
| » Defeated Twins (21-17), 10-2 | Memorial Stadium (9-10) | 17-22 | |
| » W: Mark Williamson (3-1) L: Kevin Tapani (5-3) | Sixth | 6½ out |
| Wednesday, May 23 |
| » Lost to White Sox (22-14), 6-3 | Memorial Stadium (9-11) | 17-23 | |
| » W: Eric King (3-0) L: Dave Johnson (3-3) S: Bobby Thigpen (12) | Seventh | 6½ out |
| Thursday, May 24 |
| » Lost to White Sox (23-14), 5-3 | Memorial Stadium (9-12) | 17-24 | Lost 2 |
| » W: Scott Radinsky (4-0) L: Jay Tibbs (2-5) S: Bobby Thigpen (13) | Seventh | 6½ out |
| Friday, May 25 |
| » Defeated Rangers (18-24), 12-2 | Arlington Stadium (1-0) | 18-24 | |
| » W: Pete Harnisch (5-1) L: Kevin Brown (5-4) | Seventh | 5½ out |
| Saturday, May 26 |
| » Defeated Rangers (18-25), 7-5 | Arlington Stadium (2-0) | 19-24 | Won 2 |
| » W: Gregg Olson (2-0) L: Jeff Russell (1-4) | Sixth | 4½ out |
| Sunday, May 27 |
| » Defeated Rangers (18-26), 9-2 | Arlington Stadium (3-0) | 20-24 | Won 3 |
| » W: Jeff Ballard (1-5) L: Bobby Witt (2-6) | Fifth | 3½ out |
| Monday, May 28 |
| » Lost to Twins (26-18), 6-4 | Hubert H. Humphrey Metrodome (0-1) | 20-25 | |
| » W: Juan Berenguer (4-0) L: Joe Price (0-2) S: John Candelaria (2) | Fifth | 4 out |
| Tuesday, May 29 |
| » Defeated Twins (26-19), 5-1 | Hubert H. Humphrey Metrodome (1-1) | 21-25 | |
| » W: Bob Milacki (2-3) L: Allan Anderson (2-6) | Fifth | 4 out |
| Wednesday, May 30 |
| » Lost to Twins (27-19), 12-3 | Hubert H. Humphrey Metrodome (1-2) | 21-26 | |
| » W: Roy Smith (4-4) L: Pete Harnisch (5-2) | Fifth | 4 out |
| Friday, June 1 |
| » Lost to Yankees (18-27), 4-3 | Yankee Stadium (0-1) | 21-27 | Lost 2 |
| » W: Dave LaPoint (4-4) L: Jeff Ballard (1-6) S: Dave Righetti (10) | Fifth | 4½ out |
| Saturday, June 2 |
| » Defeated Yankees (18-28), 4-2 | Yankee Stadium (1-1) | 22-27 | |
| » W: Dave Johnson (4-3) L: Tim Leary (3-6) S: Gregg Olson (10) | Fifth | 4½ out |
| Sunday, June 3 |
| » Defeated Yankees (18-29), 4-3 | Yankee Stadium (2-1) | 23-27 | Won 2 |
| » W: Bob Milacki (3-3) L: Mike Witt (0-4) S: Gregg Olson (11) | Fifth | 3½ out |
| Monday, June 4 |
| » Defeated Brewers (25-23), 6-4 | County Stadium (1-0) | 24-27 | Won 3 |
| » W: Joe Price (1-2) L: Bill Krueger (2-2) S: Gregg Olson (12) | Fifth | 3 out |
| Tuesday, June 5 |
| » Lost to Brewers (26-23), 6-4 | County Stadium (1-1) | 24-28 | |
| » W: Jaime Navarro (2-1) L: Jay Tibbs (2-6) S: Chuck Crim (4) | Fifth | 4 out |
| Wednesday, June 6 |
| » Defeated Brewers (26-24), 8-7 | County Stadium (2-1) | 25-28 | |
| » W: Mark Williamson (4-1) L: Bill Krueger (2-3) S: Gregg Olson (13) | Fourth | 4 out |
| Thursday, June 7 |
| » Defeated Brewers (26-25), 5-2 | County Stadium (3-1) | 26-28 | Won 2 |
| » W: Dave Johnson (5-3) L: Paul Mirabella (2-1) S: Gregg Olson (14) | Fourth | 4 out |
| Friday, June 8 |
| » Defeated Yankees (18-34), 5-4 | Memorial Stadium (10-12) | 27-28 | Won 3 |
| » W: Brian Holton (2-1) L: Alan Mills (0-1) | Fourth | 4 out |
| » Major-league debuts: Jim Leyritz (Yankees) |
| Saturday, June 9 |
| » Defeated Yankees (18-35), 10-1 | Memorial Stadium (11-12) | 28-28 | Won 4 |
| » W: Pete Harnisch (6-2) L: Chuck Cary (2-2) | Third | 4 out |
| Sunday, June 10 |
| » Lost to Yankees (19-35), 5-2 | Memorial Stadium (11-13) | 28-29 | |
| » W: Jimmy Jones (1-0) L: Jay Tibbs (2-7) S: Dave Righetti (11) | Third | 4 out |
| Tuesday, June 12 |
| » Defeated Brewers (27-29), 4-3 | Memorial Stadium (12-13) | 29-29 | |
| » W: Gregg Olson (3-0) L: Dan Plesac (0-3) | Third | 3 out |
| Wednesday, June 13 |
| » Lost to Brewers (28-29), 7-2 | Memorial Stadium (12-14) | 29-30 | |
| » W: Mark Knudson (4-3) L: Dave Johnson (5-4) | Third | 4 out |
| Thursday, June 14 |
| » Lost to Brewers (29-29), 8-5 | Memorial Stadium (12-15) | 29-31 | Lost 2 |
| » W: Bob Sebra (1-0) L: Brian Holton (2-2) S: Dan Plesac (12) | Fourth | 5 out |
| Friday, June 15 |
| » Lost to Red Sox (33-27), 4-3 | Memorial Stadium (12-16) | 29-32 | Lost 3 |
| » W: Wes Gardner (1-3) L: Pete Harnisch (6-3) S: Jeff Reardon (10) | Fifth | 6 out |
| Saturday, June 16 |
| » Lost to Red Sox (34-27), 6-3 | Memorial Stadium (12-17) | 29-33 | Lost 4 |
| » W: Mike Boddicker (8-3) L: John Mitchell (0-1) | Fifth | 7 out |
| Sunday, June 17 |
| » Lost to Red Sox (35-27), 6-5 | Memorial Stadium (12-18) | 29-34 | Lost 5 |
| » W: Greg Harris (6-3) L: Jeff Ballard (1-7) S: Rob Murphy (2) | Fifth | 8 out |
| Monday, June 18 |
| » Defeated Red Sox (35-28), 7-2 | Memorial Stadium (13-18) | 30-34 | |
| » W: Dave Johnson (6-4) L: Roger Clemens (11-3) | Sixth | 7½ out |
| Tuesday, June 19 |
| » Lost to Indians (30-32), 5-4 | Cleveland Stadium (0-1) | 30-35 | |
| » W: Doug Jones (2-2) L: Gregg Olson (3-1) | Sixth | 7½ out |
| Wednesday, June 20 |
| » Defeated Indians (30-33), 3-1 | Cleveland Stadium (1-1) | 31-35 | |
| » W: Pete Harnisch (7-3) L: Jesse Orosco (3-3) S: Gregg Olson (15) | Fifth | 7½ out |
| Thursday, June 21 |
| » Lost to Indians (31-33), 4-3 | Cleveland Stadium (1-2) | 31-36 | |
| » W: Doug Jones (3-2) L: Brian Holton (2-3) | Sixth | 7½ out |
| Friday, June 22 |
| » Lost to Red Sox (37-29), 4-3 | Fenway Park (0-1) | 31-37 | Lost 2 |
| » W: Mike Boddicker (9-3) L: Jeff Ballard (1-8) S: Rob Murphy (4) | Fifth | 7½ out |
| Saturday, June 23 |
| » Lost to Red Sox (38-29), 4-3 | Fenway Park (0-2) | 31-38 | Lost 3 |
| » W: Jeff Gray (1-0) L: Gregg Olson (3-2) | Sixth | 8½ out |
| Sunday, June 24 |
| » Lost to Red Sox (39-29), 2-0 | Fenway Park (0-3) | 31-39 | Lost 4 |
| » W: Greg Harris (7-3) L: Bob Milacki (3-4) S: Jeff Gray (1) | Fifth | 9½ out |
| Tuesday, June 26 |
| » Lost to Indians (34-35), 5-3 | Memorial Stadium (13-19) | 31-40 | Lost 5 |
| » W: Doug Jones (4-2) L: Pete Harnisch (7-4) | Sixth | 10½ out |
| Wednesday, June 27 |
| » Defeated Indians (34-36), 6-3 | Memorial Stadium (14-19) | 32-40 | |
| » W: Gregg Olson (4-2) L: Sergio Valdez (2-4) | Sixth | 10½ out |
| Thursday, June 28 |
| » Lost to Indians (35-36), 7-4 | Memorial Stadium (14-20) | 32-41 | |
| » W: Al Nipper (1-1) L: Jeff Ballard (1-9) | Sixth | 11½ out |
| Friday, June 29 |
| » Defeated Twins (35-39), 6-2 | Hubert H. Humphrey Metrodome (2-2) | 33-41 | |
| » W: Dave Johnson (7-4) L: Allan Anderson (2-11) S: Curt Schilling (1) | Sixth | 10½ out |
| Saturday, June 30 |
| » Defeated Twins (35-40), 6-0 | Hubert H. Humphrey Metrodome (3-2) | 34-41 | Won 2 |
| » W: Bob Milacki (4-4) L: Scott Erickson (1-1) | Fifth | 9½ out |
| Sunday, July 1 |
| » Lost to Twins (36-40), 4-3 | Hubert H. Humphrey Metrodome (3-3) | 34-42 | |
| » W: Rick Aguilera (2-1) L: Gregg Olson (4-3) | Fifth | 10½ out |
| Tuesday, July 3 |
| » Lost to Rangers (36-43), 7-2 | Arlington Stadium (3-1) | 34-43 | Lost 2 |
| » W: Bobby Witt (5-8) L: John Mitchell (0-2) | Fifth | 11 out |
| Wednesday, July 4 |
| » Defeated Rangers (36-44), 9-4 | Arlington Stadium (4-1) | 35-43 | |
| » W: Dave Johnson (8-4) L: Charlie Hough (7-6) | Fifth | 11 out |
| Thursday, July 5 |
| » Lost to Rangers (37-44), 3-2 | Arlington Stadium (4-2) | 35-44 | |
| » W: Mike Jeffcoat (3-3) L: Bob Milacki (4-5) S: Kenny Rogers (6) | Sixth | 11 out |
| Friday, July 6 |
| » Lost to White Sox (48-28), 4-2 | Comiskey Park I (0-4) | 35-45 | Lost 2 |
| » W: Melido Perez (7-7) L: Pete Harnisch (7-5) S: Bobby Thigpen (27) | Sixth | 11 out |
| Saturday, July 7 |
| » Defeated White Sox (48-29), 4-1 | Comiskey Park I (1-4) | 36-45 | |
| » W: John Mitchell (1-2) L: Greg Hibbard (6-5) S: Gregg Olson (16) | Fifth | 10 out |
| Sunday, July 8 |
| » Defeated White Sox (48-30), 8-6 | Comiskey Park I (2-4) | 37-45 | Won 2 |
| » W: Mark Williamson (5-1) L: Bobby Thigpen (4-3) S: Gregg Olson (17) | Fifth | 9 out |
| Wednesday, July 11 |
| » Defeated Royals (36-46), 7-5 | Memorial Stadium (15-20) | 38-45 | Won 3 |
| » W: Curt Schilling (1-0) L: Steve Farr (6-4) S: Gregg Olson (18) | Fifth | 8½ out |
| Friday, July 13 |
| » Defeated Twins (40-45), 8-5 | Memorial Stadium (16-20) | 39-45 | Won 4 |
| » W: Mark Williamson (6-1) L: Juan Berenguer (6-2) S: Gregg Olson (19) | Fifth | 8 out |
| » Lost to Twins (41-45), 3-1 | Memorial Stadium (16-21) | 39-46 | |
| » W: David West (5-6) L: Dave Johnson (8-5) S: Terry Leach (1) | Fifth | 8 out |
| Saturday, July 14 |
| » Defeated Twins (41-46), 3-2 | Memorial Stadium (17-21) | 40-46 | |
| » W: Mark Williamson (7-1) L: Terry Leach (2-3) | Fifth | 7½ out |
| Sunday, July 15 |
| » Lost to Twins (42-46), 10-3 | Memorial Stadium (17-22) | 40-47 | |
| » W: Allan Anderson (3-12) L: Bob Milacki (4-6) | Fifth | 7½ out |
| Monday, July 16 |
| » Defeated Rangers (43-46), 7-6 | Memorial Stadium (18-22) | 41-47 | |
| » W: Gregg Olson (5-3) L: Kenny Rogers (3-5) | Fifth | 7 out |
| Tuesday, July 17 |
| » Defeated Rangers (43-47), 5-3 | Memorial Stadium (19-22) | 42-47 | Won 2 |
| » W: Pete Harnisch (8-5) L: Kevin Brown (11-7) S: Gregg Olson (20) | Fifth | 6½ out |
| Wednesday, July 18 |
| » Lost to Rangers (44-47), 7-1 | Memorial Stadium (19-23) | 42-48 | |
| » W: Bobby Witt (7-8) L: Dave Johnson (8-6) | Fourth | 7½ out |
| Thursday, July 19 |
| » Defeated White Sox (54-33), 4-1 | Memorial Stadium (20-23) | 43-48 | |
| » W: John Mitchell (2-2) L: Adam Peterson (0-2) S: Gregg Olson (21) | Fourth | 6½ out |
| Friday, July 20 |
| » Defeated White Sox (54-34), 3-2 | Memorial Stadium (21-23) | 44-48 | Won 2 |
| » W: Mark Williamson (8-1) L: Bobby Thigpen (4-4) | Fourth | 6 out |
| Saturday, July 21 |
| » Defeated White Sox (54-35), 2-0 | Memorial Stadium (22-23) | 45-48 | Won 3 |
| » W: Ben McDonald (1-0) L: Jack McDowell (5-5) | Third | 5½ out |
| Sunday, July 22 |
| » Defeated White Sox (54-36), 9-3 | Memorial Stadium (23-23) | 46-48 | Won 4 |
| » W: Pete Harnisch (9-5) L: Melido Perez (9-8) S: Curt Schilling (2) | Third | 4½ out |
| Monday, July 23 |
| » Defeated Tigers (45-52), 13-3 | Tiger Stadium (2-2) | 47-48 | Won 5 |
| » W: Dave Johnson (9-6) L: Frank Tanana (5-7) | Third | 4 out |
| Tuesday, July 24 |
| » Lost to Tigers (46-52), 8-2 | Tiger Stadium (2-3) | 47-49 | |
| » W: Jeff Robinson (8-7) L: John Mitchell (2-3) | Third | 4 out |
| Wednesday, July 25 |
| » Lost to Tigers (47-52), 4-3 | Tiger Stadium (2-4) | 47-50 | Lost 2 |
| » W: Mike Henneman (6-6) L: Bob Milacki (4-7) S: Jerry Don Gleaton (4) | Second | 4 out |
| Friday, July 27 |
| » Defeated Royals (45-52), 9-2 | Royals Stadium (2-1) | 48-50 | |
| » W: Ben McDonald (2-0) L: Storm Davis (4-7) | Third | 4½ out |
| » Major-league debuts: Luis Encarnacion (Royals) |
| Saturday, July 28 |
| » Lost to Royals (46-52), 10-9 | Royals Stadium (2-2) | 48-51 | |
| » W: Steve Crawford (4-2) L: Mark Williamson (8-2) S: Jeff Montgomery (14) | Third | 4 out |
| » Defeated Royals (46-53), 3-1 | Royals Stadium (3-2) | 49-51 | |
| » W: Dave Johnson (10-6) L: Steve Farr (8-5) S: Gregg Olson (22) | Third | 4 out |
| Sunday, July 29 |
| » Defeated Royals (46-54), 4-1 | Royals Stadium (4-2) | 50-51 | Won 2 |
| » W: John Mitchell (3-3) L: Tom Gordon (6-7) S: Gregg Olson (23) | Third | 4 out |
| Monday, July 30 |
| » Lost to Blue Jays (55-47), 9-2 | Memorial Stadium (23-24) | 50-52 | |
| » W: Todd Stottlemyre (10-11) L: Bob Milacki (4-8) S: Duane Ward (8) | Third | 5 out |
| Tuesday, July 31 |
| » Defeated Blue Jays (55-48), 6-4 | Memorial Stadium (24-24) | 51-52 | |
| » W: Ben McDonald (3-0) L: John Cerutti (7-7) S: Gregg Olson (24) | Second | 4 out |
| Wednesday, August 1 |
| » Lost to Blue Jays (56-48), 7-4 | Memorial Stadium (24-25) | 51-53 | |
| » W: Dave Stieb (14-3) L: Jeff Ballard (1-10) S: Tom Henke (22) | Second | 5 out |
| Thursday, August 2 |
| » Defeated Royals (48-56), 5-1 | Memorial Stadium (25-25) | 52-53 | |
| » W: Dave Johnson (11-6) L: Pete Filson (0-2) S: Gregg Olson (25) | Third | 4½ out |
| Friday, August 3 |
| » Defeated Royals (48-57), 14-1 | Memorial Stadium (26-25) | 53-53 | Won 2 |
| » W: John Mitchell (4-3) L: Tom Gordon (6-8) | Third | 4½ out |
| Saturday, August 4 |
| » Lost to Royals (49-57), 9-1 | Memorial Stadium (26-26) | 53-54 | |
| » W: Andy McGaffigan (3-0) L: Pete Harnisch (9-6) | Third | 5½ out |
| Tuesday, August 7 |
| » Lost to Athletics (69-41), 3-2 | Oakland-Alameda County Stadium (2-2) | 53-55 | Lost 2 |
| » W: Bob Welch (18-4) L: John Mitchell (4-4) S: Dennis Eckersley (36) | Third | 6 out |
| Wednesday, August 8 |
| » Defeated Athletics (69-42), 4-1 | Oakland-Alameda County Stadium (3-2) | 54-55 | |
| » W: Ben McDonald (4-0) L: Scott Sanderson (11-7) S: Gregg Olson (26) | Third | 5 out |
| Thursday, August 9 |
| » Lost to Athletics (70-42), 5-2 | Oakland-Alameda County Stadium (3-3) | 54-56 | |
| » W: Mike Moore (10-10) L: Dave Johnson (11-7) S: Dennis Eckersley (37) | Third | 6 out |
| Friday, August 10 |
| » Lost to Angels (54-59), 2-1 | Anaheim Stadium (2-2) | 54-57 | Lost 2 |
| » W: Willie Fraser (4-3) L: Gregg Olson (5-4) | Third | 6 out |
| Saturday, August 11 |
| » Lost to Angels (55-59), 12-4 | Anaheim Stadium (2-3) | 54-58 | Lost 3 |
| » W: Chuck Finley (15-5) L: Mickey Weston (0-1) | Third | 7 out |
| Sunday, August 12 |
| » Defeated Angels (55-60), 11-6 | Anaheim Stadium (3-3) | 55-58 | |
| » W: John Mitchell (5-4) L: Mark Langston (5-15) S: Mark Williamson (1) | Third | 7 out |
| Monday, August 13 |
| » Defeated Mariners (58-58), 3-2 | Kingdome (2-2) | 56-58 | Won 2 |
| » W: Ben McDonald (5-0) L: Brian Holman (11-8) S: Gregg Olson (27) | Third | 6 out |
| Tuesday, August 14 |
| » Lost to Mariners (59-58), 7-1 | Kingdome (2-3) | 56-59 | |
| » W: Matt Young (6-12) L: Dave Johnson (11-8) | Third | 7 out |
| Wednesday, August 15 |
| » Lost to Mariners (60-58), 2-0 | Kingdome (2-4) | 56-60 | Lost 2 |
| » W: Randy Johnson (11-7) L: Pete Harnisch (9-7) | Third | 7 out |
| Friday, August 17 |
| » Lost to Athletics (76-43), 8-3 | Memorial Stadium (26-27) | 56-61 | Lost 3 |
| » W: Bob Welch (20-4) L: John Mitchell (5-5) | Third | 7 out |
| Saturday, August 18 |
| » Lost to Athletics (77-43), 3-1 | Memorial Stadium (26-28) | 56-62 | Lost 4 |
| » W: Gene Nelson (3-2) L: Ben McDonald (5-1) S: Dennis Eckersley (38) | Third | 7 out |
| Sunday, August 19 |
| » Defeated Athletics (77-44), 3-2 | Memorial Stadium (27-28) | 57-62 | |
| » W: Anthony Telford (1-0) L: Scott Sanderson (12-8) S: Gregg Olson (28) | Third | 7 out |
| » Major-league debuts: Anthony Telford (Orioles) |
| Monday, August 20 |
| » Lost to Red Sox (65-55), 2-1 | Fenway Park (0-4) | 57-63 | |
| » W: Greg Harris (10-5) L: Pete Harnisch (9-8) S: Jeff Gray (4) | Third | 8 out |
| Tuesday, August 21 |
| » Defeated Red Sox (65-56), 9-5 | Fenway Park (1-4) | 58-63 | |
| » W: John Mitchell (6-5) L: Dana Kiecker (4-6) S: Gregg Olson (29) | Third | 7 out |
| » Major-league debuts: Phil Plantier (Red Sox) |
| Wednesday, August 22 |
| » Lost to Red Sox (66-56), 13-2 | Fenway Park (1-5) | 58-64 | |
| » W: Mike Boddicker (12-8) L: Ben McDonald (5-2) | Third | 8 out |
| Friday, August 24 |
| » Defeated Indians (57-67), 5-4 | Memorial Stadium (28-28) | 59-64 | |
| » W: Joe Price (2-2) L: Colby Ward (1-2) | Third | 7½ out |
| Saturday, August 25 |
| » Lost to Indians (58-67), 11-5 | Memorial Stadium (28-29) | 59-65 | |
| » W: Steve Olin (2-4) L: Pete Harnisch (9-9) | Third | 8½ out |
| Sunday, August 26 |
| » Lost to Indians (59-67), 8-3 | Memorial Stadium (28-30) | 59-66 | Lost 2 |
| » W: Greg Swindell (10-7) L: Joe Price (2-3) | Third | 9½ out |
| Monday, August 27 |
| » Lost to Yankees (54-73), 4-0 | Memorial Stadium (28-31) | 59-67 | Lost 3 |
| » W: Andy Hawkins (5-10) L: Ben McDonald (5-3) S: Dave Righetti (28) | Fourth | 10½ out |
| Tuesday, August 28 |
| » Lost to Yankees (55-73), 11-3 | Memorial Stadium (28-32) | 59-68 | Lost 4 |
| » W: Mike Witt (3-6) L: Jose Mesa (0-1) | Fourth | 11½ out |
| Wednesday, August 29 |
| » Lost to Yankees (56-73), 3-2 | Memorial Stadium (28-33) | 59-69 | Lost 5 |
| » W: Tim Leary (8-16) L: Anthony Telford (1-1) S: Dave Righetti (29) | Fifth | 12½ out |
| Thursday, August 30 |
| » Defeated Yankees (56-74), 6-1 | Memorial Stadium (29-33) | 60-69 | |
| » W: Pete Harnisch (10-9) L: Dave LaPoint (6-10) | Fourth | 12½ out |
| Friday, August 31 |
| » Lost to Brewers (61-69), 4-1 | County Stadium (3-2) | 60-70 | |
| » W: Ron Robinson (10-5) L: John Mitchell (6-6) | Fifth | 13½ out |
| Saturday, September 1 |
| » Lost to Brewers (62-69), 4-3 | County Stadium (3-3) | 60-71 | Lost 2 |
| » W: Teddy Higuera (9-6) L: Ben McDonald (5-4) S: Dan Plesac (22) | Fifth | 14½ out |
| Sunday, September 2 |
| » Lost to Brewers (63-69), 4-2 | County Stadium (3-4) | 60-72 | Lost 3 |
| » W: Jaime Navarro (6-5) L: Jose Mesa (0-2) S: Chuck Crim (9) | Fifth | 15½ out |
| Monday, September 3 |
| » Lost to Mariners (66-69), 6-2 | Memorial Stadium (29-34) | 60-73 | Lost 4 |
| » W: Matt Young (7-14) L: Anthony Telford (1-2) | Fifth | 15½ out |
| Tuesday, September 4 |
| » Lost to Mariners (67-69), 7-2 | Memorial Stadium (29-35) | 60-74 | Lost 5 |
| » W: Erik Hanson (13-9) L: Pete Harnisch (10-10) | Fifth | 15½ out |
| Wednesday, September 5 |
| » Lost to Mariners (68-69), 9-5 | Memorial Stadium (29-36) | 60-75 | Lost 6 |
| » W: Keith Comstock (7-3) L: Kevin Hickey (1-3) | Fifth | 15½ out |
| Friday, September 7 |
| » Defeated Angels (69-69), 6-2 | Memorial Stadium (30-36) | 61-75 | |
| » W: Ben McDonald (6-4) L: Joe Grahe (1-3) | Fifth | 15½ out |
| Saturday, September 8 |
| » Defeated Angels (69-70), 5-4 | Memorial Stadium (31-36) | 62-75 | Won 2 |
| » W: Joe Price (3-3) L: Mark Eichhorn (2-5) | Fifth | 15½ out |
| Sunday, September 9 |
| » Defeated Angels (69-71), 3-1 | Memorial Stadium (32-36) | 63-75 | Won 3 |
| » W: Anthony Telford (2-2) L: Kirk McCaskill (11-10) S: Gregg Olson (30) | Fifth | 14½ out |
| Monday, September 10 |
| » Lost to Tigers (68-74), 8-0 | Memorial Stadium (32-37) | 63-76 | |
| » W: Frank Tanana (7-7) L: Pete Harnisch (10-11) | Fifth | 15 out |
| Tuesday, September 11 |
| » Lost to Tigers (69-74), 2-1 | Memorial Stadium (32-38) | 63-77 | Lost 2 |
| » W: Paul Gibson (5-4) L: Curt Schilling (1-1) S: Jerry Don Gleaton (10) | Fifth | 15 out |
| Wednesday, September 12 |
| » Defeated Tigers (69-75), 2-1 | Memorial Stadium (33-38) | 64-77 | |
| » W: Ben McDonald (7-4) L: Jack Morris (11-18) | Fifth | 15 out |
| Thursday, September 13 |
| » Defeated Blue Jays (76-68), 5-3 | Skydome (2-2) | 65-77 | Won 2 |
| » W: Jose Mesa (1-2) L: Dave Stieb (18-6) S: Gregg Olson (31) | Fifth | 14 out |
| Friday, September 14 |
| » Lost to Blue Jays (77-68), 8-7 | Skydome (2-3) | 65-78 | |
| » W: Willie Blair (2-5) L: Gregg Olson (5-5) | Fifth | 14 out |
| Saturday, September 15 |
| » Lost to Blue Jays (78-68), 4-3 | Skydome (2-4) | 65-79 | Lost 2 |
| » W: Willie Blair (3-5) L: Curt Schilling (1-2) | Sixth | 14 out |
| Sunday, September 16 |
| » Lost to Blue Jays (79-68), 6-5 | Skydome (2-5) | 65-80 | Lost 3 |
| » W: Tom Henke (2-2) L: Joe Price (3-4) | Sixth | 14 out |
| Monday, September 17 |
| » Lost to Red Sox (81-67), 7-3 | Memorial Stadium (33-39) | 65-81 | Lost 4 |
| » W: Mike Boddicker (16-8) L: Ben McDonald (7-5) | Sixth | 15 out |
| » Major-league debuts: Leo Gomez (Orioles) |
| Tuesday, September 18 |
| » Defeated Red Sox (81-68), 4-1 | Memorial Stadium (34-39) | 66-81 | |
| » W: Jose Mesa (2-2) L: Tom Bolton (9-4) S: Gregg Olson (32) | Fifth | 14 out |
| Wednesday, September 19 |
| » Defeated Red Sox (81-69), 8-4 | Memorial Stadium (35-39) | 67-81 | Won 2 |
| » W: Anthony Telford (3-2) L: Greg Harris (13-8) S: Curt Schilling (3) | Sixth | 14 out |
| Friday, September 21 |
| » Defeated Brewers (69-81), 5-3 | Memorial Stadium (36-39) | 68-81 | Won 3 |
| » W: Pete Harnisch (11-11) L: Ron Robinson (13-6) S: Gregg Olson (33) | Fifth | 13 out |
| Saturday, September 22 |
| » Defeated Brewers (69-82), 3-2 | Memorial Stadium (37-39) | |