| Monday, April 9 |
| » Lost to White Sox (1-0), 2-1 | Comiskey Park I (0-1) | 0-1 | |
| » W: Barry Jones (1-0) L: Tony Fossas (0-1) S: Bobby Thigpen (1) | Third | 1 out |
| » Major-league debuts: Scott Radinsky (White Sox) |
| Tuesday, April 10 |
| » Lost to White Sox (2-0), 5-3 | County Stadium (0-1) | 0-2 | Lost 2 |
| » W: Scott Radinsky (1-0) L: Tom Filer (0-1) S: Bobby Thigpen (2) | Fifth | 2 out |
| Friday, April 13 |
| » Defeated Red Sox (3-2), 9-5 | Fenway Park (1-0) | 1-2 | |
| » W: Chuck Crim (1-0) L: Rob Murphy (0-1) | Fifth | 1½ out |
| Saturday, April 14 |
| » Lost to Red Sox (4-2), 4-3 | Fenway Park (1-1) | 1-3 | |
| » W: Roger Clemens (2-0) L: Don August (0-1) S: Lee Smith (3) | Seventh | 2 out |
| Sunday, April 15 |
| » Major-league debuts: Kevin Bearse (Indians) |
| Monday, April 16 |
| » Defeated Red Sox (4-3), 18-0 | Fenway Park (2-1) | 2-3 | |
| » W: Teddy Higuera (1-0) L: Mike Boddicker (1-1) | Fifth | 1½ out |
| Tuesday, April 17 |
| » Lost to Rangers (4-4), 6-2 | Arlington Stadium (0-1) | 2-4 | |
| » W: Kevin Brown (2-0) L: Tony Fossas (0-2) S: Mike Jeffcoat (2) | Fifth | 2½ out |
| Wednesday, April 18 |
| » Defeated Rangers (4-5), 11-6 | Arlington Stadium (1-1) | 3-4 | |
| » W: Tony Fossas (1-2) L: Jamie Moyer (0-2) | Fifth | 1½ out |
| Thursday, April 19 |
| » Defeated Rangers (4-6), 11-0 | Arlington Stadium (2-1) | 4-4 | Won 2 |
| » W: Chris Bosio (1-0) L: Bobby Witt (0-2) | Fourth | 1 out |
| » Major-league debuts: Ramon Manon (Rangers) |
| Friday, April 20 |
| » Defeated Red Sox (5-5), 5-0 | County Stadium (1-1) | 5-4 | Won 3 |
| » W: Tom Filer (1-1) L: Mike Boddicker (1-2) S: Chuck Crim (1) | Second | 1 out |
| Saturday, April 21 |
| » Defeated Red Sox (5-6), 2-0 | County Stadium (2-1) | 6-4 | Won 4 |
| » W: Teddy Higuera (2-0) L: Eric Hetzel (0-1) | Second | 1 out |
| Sunday, April 22 |
| » Lost to Red Sox (6-6), 4-2 | County Stadium (2-2) | 6-5 | |
| » W: Lee Smith (1-1) L: Dan Plesac (0-1) | Second | 1 out |
| Tuesday, April 24 |
| » Defeated Royals (5-8), 7-3 | County Stadium (3-2) | 7-5 | |
| » W: Chris Bosio (2-0) L: Richard Dotson (0-1) | Second | 1½ out |
| Wednesday, April 25 |
| » Defeated Royals (5-9), 1-0 | County Stadium (4-2) | 8-5 | Won 2 |
| » W: Tom Filer (2-1) L: Bret Saberhagen (1-2) S: Dan Plesac (1) | Second | 1½ out |
| Thursday, April 26 |
| » Defeated Royals (5-10), 3-2 | County Stadium (5-2) | 9-5 | Won 3 |
| » W: Mark Knudson (1-0) L: Mark Gubicza (1-3) S: Dan Plesac (2) | Second | 1½ out |
| Friday, April 27 |
| » Defeated Tigers (7-10), 9-6 | Tiger Stadium (1-0) | 10-5 | Won 4 |
| » W: Bill Krueger (1-0) L: Jack Morris (2-2) S: Chuck Crim (2) | First | -- |
| Saturday, April 28 |
| » Lost to Tigers (8-10), 13-5 | Tiger Stadium (1-1) | 10-6 | |
| » W: Frank Tanana (2-1) L: Don August (0-2) | First | -- |
| Sunday, April 29 |
| » Defeated Tigers (8-11), 6-1 | Tiger Stadium (2-1) | 11-6 | |
| » W: Chris Bosio (3-0) L: Dan Petry (1-1) | First | -- |
| Monday, April 30 |
| » Defeated Tigers (8-12), 6-1 | Tiger Stadium (3-1) | 12-6 | Won 2 |
| » W: Mark Knudson (2-0) L: Jeff Robinson (1-2) | First | -- |
| Tuesday, May 1 |
| » Defeated Royals (6-13), 6-4 | Royals Stadium (1-0) | 13-6 | Won 3 |
| » W: Teddy Higuera (3-0) L: Bret Saberhagen (1-3) S: Dan Plesac (3) | First | -- |
| » Major-league debuts: Terry Shumpert (Royals) |
| Thursday, May 3 |
| » Defeated Royals (6-14), 9-5 | Royals Stadium (2-0) | 14-6 | Won 4 |
| » W: Jaime Navarro (1-0) L: Mark Gubicza (1-4) S: Dan Plesac (4) | First | -- |
| Saturday, May 5 |
| » Lost to Twins (11-12), 9-5 | County Stadium (5-3) | 14-7 | |
| » W: John Candelaria (3-0) L: Chuck Crim (1-1) | First | -- |
| Sunday, May 6 |
| » Lost to Twins (12-12), 4-0 | County Stadium (5-4) | 14-8 | Lost 2 |
| » W: Kevin Tapani (3-2) L: Teddy Higuera (3-1) | First | -- |
| Monday, May 7 |
| » Defeated Tigers (9-18), 5-4 | County Stadium (6-4) | 15-8 | |
| » W: Bill Krueger (2-0) L: Jack Morris (2-4) S: Dan Plesac (5) | First | -- |
| Tuesday, May 8 |
| » Defeated Tigers (9-19), 7-5 | County Stadium (7-4) | 16-8 | Won 2 |
| » W: Paul Mirabella (1-0) L: Frank Tanana (2-2) S: Dan Plesac (6) | First | -- |
| Wednesday, May 9 |
| » Lost to Tigers (10-19), 2-1 | County Stadium (7-5) | 16-9 | |
| » W: Dan Petry (3-1) L: Chris Bosio (3-1) S: Mike Henneman (7) | First | -- |
| Friday, May 11 |
| » Defeated Twins (14-14), 6-3 | Hubert H. Humphrey Metrodome (1-0) | 17-9 | |
| » W: Bill Wegman (1-0) L: Allan Anderson (1-4) S: Dan Plesac (7) | First | -- |
| Saturday, May 12 |
| » Lost to Twins (15-14), 5-2 | Hubert H. Humphrey Metrodome (1-1) | 17-10 | |
| » W: Kevin Tapani (4-2) L: Mark Knudson (2-1) S: Rick Aguilera (8) | First | -- |
| Sunday, May 13 |
| » Lost to Twins (16-14), 8-6 | Hubert H. Humphrey Metrodome (1-2) | 17-11 | Lost 2 |
| » W: Juan Berenguer (3-0) L: Bill Krueger (2-1) S: Rick Aguilera (9) | First | -- |
| Tuesday, May 15 |
| » Lost to Angels (13-20), 8-3 | County Stadium (7-6) | 17-12 | Lost 3 |
| » W: Mark Langston (3-3) L: Chris Bosio (3-2) | Second | 2½ out |
| Wednesday, May 16 |
| » Defeated Angels (13-21), 13-5 | County Stadium (8-6) | 18-12 | |
| » W: Teddy Higuera (4-1) L: Jim Abbott (1-3) | First | -- |
| Thursday, May 17 |
| » Defeated Angels (13-22), 6-3 | County Stadium (9-6) | 19-12 | Won 2 |
| » W: Paul Mirabella (2-0) L: Willie Fraser (0-2) S: Dan Plesac (8) | First | -- |
| Friday, May 18 |
| » Defeated Athletics (23-11), 5-0 | County Stadium (10-6) | 20-12 | Won 3 |
| » W: Bill Wegman (2-0) L: Mike Moore (3-3) | First | -- |
| Saturday, May 19 |
| » Lost to Athletics (24-11), 9-1 | County Stadium (10-7) | 20-13 | |
| » W: Dave Stewart (7-1) L: Tom Filer (2-2) S: Gene Nelson (3) | First | -- |
| Sunday, May 20 |
| » Defeated Athletics (24-12), 5-2 | County Stadium (11-7) | 21-13 | |
| » W: Chris Bosio (4-2) L: Scott Sanderson (4-2) | First | -- |
| Monday, May 21 |
| » Lost to Mariners (20-20), 9-4 | County Stadium (11-8) | 21-14 | |
| » W: Bryan Clark (1-0) L: Dan Plesac (0-2) | First | -- |
| Tuesday, May 22 |
| » Defeated Mariners (20-21), 3-2 | County Stadium (12-8) | 22-14 | |
| » W: Mark Knudson (3-1) L: Bill Swift (2-1) | First | -- |
| Wednesday, May 23 |
| » Lost to Athletics (27-12), 12-5 | Oakland-Alameda County Stadium (0-1) | 22-15 | |
| » W: Mike Moore (4-3) L: Bill Wegman (2-1) | First | -- |
| Thursday, May 24 |
| » Lost to Athletics (28-12), 13-1 | Oakland-Alameda County Stadium (0-2) | 22-16 | Lost 2 |
| » W: Dave Stewart (8-1) L: Tom Filer (2-3) | First | -- |
| Friday, May 25 |
| » Lost to Angels (20-23), 5-4 | Anaheim Stadium (0-1) | 22-17 | Lost 3 |
| » W: Willie Fraser (2-2) L: Tony Fossas (1-3) | First | -- |
| Saturday, May 26 |
| » Lost to Angels (21-23), 10-3 | Anaheim Stadium (0-2) | 22-18 | Lost 4 |
| » W: Bert Blyleven (3-3) L: Mark Knudson (3-2) | First | -- |
| Sunday, May 27 |
| » Lost to Angels (22-23), 7-3 | Anaheim Stadium (0-3) | 22-19 | Lost 5 |
| » W: Chuck Finley (7-2) L: Bill Wegman (2-2) | First | -- |
| Monday, May 28 |
| » Lost to Mariners (22-25), 4-3 | Kingdome (0-1) | 22-20 | Lost 6 |
| » W: Erik Hanson (5-3) L: Jaime Navarro (1-1) S: Mike Schooler (13) | Second | 2½ out |
| Tuesday, May 29 |
| » Defeated Mariners (22-26), 5-3 | Kingdome (1-1) | 23-20 | |
| » W: Chuck Crim (2-1) L: Mike Jackson (1-3) S: Dan Plesac (9) | Second | 2½ out |
| Wednesday, May 30 |
| » Lost to Mariners (23-26), 2-1 | Kingdome (1-2) | 23-21 | |
| » W: Bryan Clark (2-0) L: Chris Bosio (4-3) S: Mike Schooler (14) | Second | 2½ out |
| Friday, June 1 |
| » Defeated Blue Jays (26-24), 7-1 | Skydome (1-0) | 24-21 | |
| » W: Teddy Higuera (5-1) L: Todd Stottlemyre (4-6) S: Chuck Crim (3) | First | -- |
| Saturday, June 2 |
| » Defeated Blue Jays (26-25), 7-6 | Skydome (2-0) | 25-21 | Won 2 |
| » W: Tony Fossas (2-3) L: David Wells (2-1) S: Dan Plesac (10) | First | -- |
| Sunday, June 3 |
| » Lost to Blue Jays (27-25), 7-4 | Skydome (2-1) | 25-22 | |
| » W: Dave Stieb (7-2) L: Mark Knudson (3-3) S: Tom Henke (7) | First | -- |
| Monday, June 4 |
| » Lost to Orioles (24-27), 6-4 | County Stadium (12-9) | 25-23 | Lost 2 |
| » W: Joe Price (1-2) L: Bill Krueger (2-2) S: Gregg Olson (12) | Second | ½ out |
| Tuesday, June 5 |
| » Defeated Orioles (24-28), 6-4 | County Stadium (13-9) | 26-23 | |
| » W: Jaime Navarro (2-1) L: Jay Tibbs (2-6) S: Chuck Crim (4) | Second | ½ out |
| Wednesday, June 6 |
| » Lost to Orioles (25-28), 8-7 | County Stadium (13-10) | 26-24 | |
| » W: Mark Williamson (4-1) L: Bill Krueger (2-3) S: Gregg Olson (13) | Second | 1½ out |
| Thursday, June 7 |
| » Lost to Orioles (26-28), 5-2 | County Stadium (13-11) | 26-25 | Lost 2 |
| » W: Dave Johnson (5-3) L: Paul Mirabella (2-1) S: Gregg Olson (14) | Third | 2½ out |
| Friday, June 8 |
| » Lost to Blue Jays (30-26), 11-5 | County Stadium (13-12) | 26-26 | Lost 3 |
| » W: Tom Gilles (1-0) L: Chuck Crim (2-2) S: Tom Henke (8) | Third | 3½ out |
| Saturday, June 9 |
| » Lost to Blue Jays (31-26), 7-3 | County Stadium (13-13) | 26-27 | Lost 4 |
| » W: Dave Stieb (8-2) L: Chris Bosio (4-4) | Fourth | 4½ out |
| Sunday, June 10 |
| » Lost to Blue Jays (32-26), 13-5 | County Stadium (13-14) | 26-28 | Lost 5 |
| » W: David Wells (4-1) L: Jaime Navarro (2-2) | Fourth | 4½ out |
| Monday, June 11 |
| » Defeated Blue Jays (32-27), 4-1 | County Stadium (14-14) | 27-28 | |
| » W: Bill Krueger (3-3) L: Willie Blair (0-3) S: Dan Plesac (11) | Third | 3½ out |
| Tuesday, June 12 |
| » Lost to Orioles (29-29), 4-3 | Memorial Stadium (0-1) | 27-29 | |
| » W: Gregg Olson (3-0) L: Dan Plesac (0-3) | Fourth | 4 out |
| Wednesday, June 13 |
| » Defeated Orioles (29-30), 7-2 | Memorial Stadium (1-1) | 28-29 | |
| » W: Mark Knudson (4-3) L: Dave Johnson (5-4) | Fourth | 4 out |
| Thursday, June 14 |
| » Defeated Orioles (29-31), 8-5 | Memorial Stadium (2-1) | 29-29 | Won 2 |
| » W: Bob Sebra (1-0) L: Brian Holton (2-2) S: Dan Plesac (12) | Third | 4 out |
| Friday, June 15 |
| » Lost to Indians (27-32), 5-3 | Cleveland Stadium (0-1) | 29-30 | |
| » W: Tom Candiotti (7-3) L: Dennis Powell (0-1) S: Doug Jones (21) | Third | 5 out |
| Saturday, June 16 |
| » Lost to Indians (28-32), 10-9 | Cleveland Stadium (0-2) | 29-31 | Lost 2 |
| » W: Doug Jones (1-2) L: Bob Sebra (1-1) | Fourth | 6 out |
| Sunday, June 17 |
| » Lost to Indians (29-32), 12-4 | Cleveland Stadium (0-3) | 29-32 | Lost 3 |
| » W: Bud Black (6-3) L: Ron Robinson (2-3) | Fourth | 7 out |
| Monday, June 18 |
| » Defeated Yankees (21-40), 4-2 | County Stadium (15-14) | 30-32 | |
| » W: Mark Knudson (5-3) L: Tim Leary (3-9) S: Chuck Crim (5) | Fourth | 6½ out |
| Tuesday, June 19 |
| » Lost to Yankees (22-40), 5-1 | County Stadium (15-15) | 30-33 | |
| » W: Chuck Cary (4-2) L: Chris Bosio (4-5) | Fifth | 6½ out |
| Wednesday, June 20 |
| » Lost to Yankees (23-40), 5-4 | County Stadium (15-16) | 30-34 | Lost 2 |
| » W: Lee Guetterman (4-2) L: Chuck Crim (2-3) | Sixth | 7½ out |
| Friday, June 22 |
| » Defeated Indians (31-34), 9-7 | County Stadium (16-16) | 31-34 | |
| » W: Tom Edens (1-0) L: Bud Black (6-4) S: Dan Plesac (13) | Third | 6 out |
| Saturday, June 23 |
| » Defeated Indians (31-35), 11-1 | County Stadium (17-16) | 32-34 | Won 2 |
| » W: Ron Robinson (3-3) L: Al Nipper (0-1) | Third | 6 out |
| Sunday, June 24 |
| » Lost to Indians (32-35), 9-5 | County Stadium (17-17) | 32-35 | |
| » W: John Farrell (4-4) L: Mark Knudson (5-4) | Third | 7 out |
| Monday, June 25 |
| » Lost to Indians (33-35), 10-5 | County Stadium (17-18) | 32-36 | Lost 2 |
| » W: Tom Candiotti (8-3) L: Chris Bosio (4-6) | Fourth | 7½ out |
| Tuesday, June 26 |
| » Lost to Yankees (26-42), 8-2 | Yankee Stadium (0-1) | 32-37 | Lost 3 |
| » W: Lee Guetterman (5-2) L: Dennis Powell (0-2) | Fourth | 8½ out |
| Wednesday, June 27 |
| » Defeated Yankees (26-43), 5-4 | Yankee Stadium (1-1) | 33-37 | |
| » W: Bill Krueger (4-3) L: Jimmy Jones (1-1) S: Chuck Crim (6) | Fourth | 8½ out |
| Thursday, June 28 |
| » Lost to Yankees (27-43), 3-2 | Yankee Stadium (1-2) | 33-38 | |
| » W: Dave Righetti (1-0) L: Bob Sebra (1-2) | Fifth | 9½ out |
| Friday, June 29 |
| » Lost to Mariners (38-38), 4-2 | Kingdome (1-3) | 33-39 | Lost 2 |
| » W: Randy Johnson (8-3) L: Chuck Crim (2-4) S: Mike Schooler (20) | Fifth | 9½ out |
| Saturday, June 30 |
| » Lost to Mariners (39-38), 6-2 | Kingdome (1-4) | 33-40 | Lost 3 |
| » W: Erik Hanson (8-6) L: Teddy Higuera (5-2) | Sixth | 9½ out |
| Sunday, July 1 |
| » Lost to Mariners (40-38), 6-5 | Kingdome (1-5) | 33-41 | Lost 4 |
| » W: Keith Comstock (4-2) L: Paul Mirabella (2-2) | Sixth | 10½ out |
| Tuesday, July 3 |
| » Lost to Athletics (49-27), 5-0 | County Stadium (17-19) | 33-42 | Lost 5 |
| » W: Curt Young (4-2) L: Bill Krueger (4-4) | Sixth | 11 out |
| Wednesday, July 4 |
| » Defeated Athletics (49-28), 7-1 | County Stadium (18-19) | 34-42 | |
| » W: Ron Robinson (4-3) L: Dave Stewart (10-7) | Sixth | 11 out |
| » Major-league debuts: Reggie Harris (Athletics) |
| Thursday, July 5 |
| » Defeated Athletics (49-29), 4-3 | County Stadium (19-19) | 35-42 | Won 2 |
| » W: Teddy Higuera (6-2) L: Bob Welch (13-3) S: Dan Plesac (14) | Fifth | 10 out |
| Friday, July 6 |
| » Lost to Angels (40-42), 9-8 | County Stadium (19-20) | 35-43 | |
| » W: Greg Minton (1-0) L: Tom Edens (1-1) | Fifth | 10 out |
| Saturday, July 7 |
| » Lost to Angels (41-42), 4-3 | County Stadium (19-21) | 35-44 | Lost 2 |
| » W: Mike Fetters (1-1) L: Randy Veres (0-1) | Sixth | 10 out |
| Sunday, July 8 |
| » Defeated Angels (41-43), 20-7 | County Stadium (20-21) | 36-44 | |
| » W: Tom Edens (2-1) L: Greg Minton (1-1) | Sixth | 9 out |
| Wednesday, July 11 |
| » Defeated White Sox (48-31), 12-9 | Comiskey Park I (1-1) | 37-44 | Won 2 |
| » W: Dan Plesac (1-3) L: Donn Pall (0-3) | Sixth | 8½ out |
| Thursday, July 12 |
| » Lost to Athletics (53-31), 5-3 | Oakland-Alameda County Stadium (0-3) | 37-45 | |
| » W: Mike Moore (8-7) L: Teddy Higuera (6-3) S: Dennis Eckersley (27) | Sixth | 9 out |
| Friday, July 13 |
| » Defeated Athletics (53-32), 2-0 | Oakland-Alameda County Stadium (1-3) | 38-45 | |
| » W: Mark Knudson (6-4) L: Dave Stewart (11-8) | Sixth | 8 out |
| Saturday, July 14 |
| » Lost to Athletics (54-32), 3-1 | Oakland-Alameda County Stadium (1-4) | 38-46 | |
| » W: Bob Welch (14-3) L: Bill Krueger (4-5) S: Dennis Eckersley (28) | Sixth | 8½ out |
| Sunday, July 15 |
| » Lost to Athletics (55-32), 4-1 | Oakland-Alameda County Stadium (1-5) | 38-47 | Lost 2 |
| » W: Curt Young (5-3) L: Chris Bosio (4-7) S: Rick Honeycutt (3) | Sixth | 8½ out |
| Monday, July 16 |
| » Defeated Angels (44-46), 3-1 | Anaheim Stadium (1-3) | 39-47 | |
| » W: Ron Robinson (5-3) L: Mark Langston (4-11) S: Dan Plesac (15) | Sixth | 8 out |
| » Major-league debuts: Lee Stevens (Angels) |
| Tuesday, July 17 |
| » Lost to Angels (45-46), 8-1 | Anaheim Stadium (1-4) | 39-48 | |
| » W: Kirk McCaskill (7-6) L: Teddy Higuera (6-4) | Sixth | 8½ out |
| Wednesday, July 18 |
| » Defeated Angels (45-47), 3-2 | Anaheim Stadium (2-4) | 40-48 | |
| » W: Mark Knudson (7-4) L: Jim Abbott (6-8) S: Dan Plesac (16) | Sixth | 8½ out |
| Thursday, July 19 |
| » Defeated Mariners (47-46), 4-0 | County Stadium (21-21) | 41-48 | Won 2 |
| » W: Bill Krueger (5-5) L: Randy Johnson (9-5) S: Jaime Navarro (1) | Sixth | 7½ out |
| Friday, July 20 |
| » Lost to Mariners (48-46), 6-4 | County Stadium (21-22) | 41-49 | |
| » W: Keith Comstock (5-2) L: Randy Veres (0-2) S: Mike Schooler (25) | Sixth | 8 out |
| Saturday, July 21 |
| » Defeated Mariners (48-47), 10-3 | County Stadium (22-22) | 42-49 | |
| » W: Ron Robinson (6-3) L: Erik Hanson (10-8) S: Randy Veres (1) | Sixth | 7½ out |
| Sunday, July 22 |
| » Lost to Mariners (49-47), 4-3 | County Stadium (22-23) | 42-50 | |
| » W: Brian Holman (9-7) L: Teddy Higuera (6-5) S: Mike Schooler (26) | Sixth | 7½ out |
| Monday, July 23 |
| » Defeated Red Sox (50-45), 13-0 | County Stadium (23-23) | 43-50 | |
| » W: Mark Knudson (8-4) L: Mike Boddicker (11-6) | Sixth | 7 out |
| Tuesday, July 24 |
| » Defeated Red Sox (50-46), 6-5 | County Stadium (24-23) | 44-50 | Won 2 |
| » W: Dan Plesac (2-3) L: Jerry Reed (2-2) | Sixth | 6 out |
| Wednesday, July 25 |
| » Lost to Red Sox (51-46), 2-0 | County Stadium (24-24) | 44-51 | |
| » W: Roger Clemens (13-5) L: Chris Bosio (4-8) | Fifth | 6 out |
| Friday, July 27 |
| » Lost to White Sox (57-37), 7-4 | Comiskey Park I (1-2) | 44-52 | Lost 2 |
| » W: Jack McDowell (6-5) L: Ron Robinson (6-4) | Sixth | 7½ out |
| » Major-league debuts: Kevin Brown (Brewers) |
| Saturday, July 28 |
| » Lost to White Sox (58-37), 5-4 | Comiskey Park I (1-3) | 44-53 | Lost 3 |
| » W: Scott Radinsky (6-0) L: Dan Plesac (2-4) | Sixth | 7½ out |
| Sunday, July 29 |
| » Defeated White Sox (58-38), 9-8 | Comiskey Park I (2-3) | 45-53 | |
| » W: Paul Mirabella (3-2) L: Scott Radinsky (6-1) S: Tom Edens (1) | Sixth | 7½ out |
| Monday, July 30 |
| » Lost to Rangers (51-50), 3-1 | County Stadium (24-25) | 45-54 | |
| » W: Bobby Witt (9-8) L: Bill Krueger (5-6) S: Brad Arnsberg (2) | Sixth | 8½ out |
| Tuesday, July 31 |
| » Lost to Rangers (52-50), 11-3 | County Stadium (24-26) | 45-55 | Lost 2 |
| » W: Nolan Ryan (11-4) L: Chris Bosio (4-9) S: Brad Arnsberg (3) | Fifth | 8½ out |
| Wednesday, August 1 |
| » Lost to Rangers (53-50), 8-2 | County Stadium (24-27) | 45-56 | Lost 3 |
| » W: Charlie Hough (8-7) L: Ron Robinson (6-5) | Fifth | 9½ out |
| Thursday, August 2 |
| » Lost to White Sox (59-41), 4-3 | County Stadium (24-28) | 45-57 | Lost 4 |
| » W: Barry Jones (11-1) L: Randy Veres (0-3) S: Bobby Thigpen (33) | Sixth | 10½ out |
| » Lost to White Sox (60-41), 4-2 | County Stadium (24-29) | 45-58 | Lost 5 |
| » W: Melido Perez (10-8) L: Jaime Navarro (2-3) S: Bobby Thigpen (34) | Sixth | 10½ out |
| » Major-league debuts: Alex Fernandez and Frank Thomas (White Sox) |
| Friday, August 3 |
| » Lost to White Sox (61-41), 6-2 | County Stadium (24-30) | 45-59 | Lost 6 |
| » W: Greg Hibbard (9-5) L: Mark Knudson (8-5) | Sixth | 11½ out |
| Saturday, August 4 |
| » Lost to White Sox (62-41), 9-6 | County Stadium (24-31) | 45-60 | Lost 7 |
| » W: Adam Peterson (2-3) L: Bill Krueger (5-7) S: Bobby Thigpen (35) | Sixth | 12½ out |
| Sunday, August 5 |
| » Lost to White Sox (63-41), 6-1 | County Stadium (24-32) | 45-61 | Lost 8 |
| » W: Jack McDowell (7-6) L: Dennis Powell (0-3) | Sixth | 12½ out |
| Monday, August 6 |
| » Defeated Twins (51-59), 6-0 | Hubert H. Humphrey Metrodome (2-2) | 46-61 | |
| » W: Ron Robinson (7-5) L: Roy Smith (5-10) | Sixth | 12 out |
| Tuesday, August 7 |
| » Defeated Twins (51-60), 5-3 | Hubert H. Humphrey Metrodome (3-2) | 47-61 | Won 2 |
| » W: Jaime Navarro (3-3) L: Mark Guthrie (3-5) S: Tom Edens (2) | Sixth | 12 out |
| Wednesday, August 8 |
| » Lost to Twins (52-60), 4-2 | Hubert H. Humphrey Metrodome (3-3) | 47-62 | |
| » W: Scott Erickson (3-2) L: Mark Knudson (8-6) S: Rick Aguilera (24) | Sixth | 12 out |
| Friday, August 10 |
| » Lost to Royals (53-58), 6-5 | Royals Stadium (2-1) | 47-63 | Lost 2 |
| » W: Jeff Montgomery (5-2) L: Dan Plesac (2-5) | Sixth | 13 out |
| » Lost to Royals (54-58), 9-4 | Royals Stadium (2-2) | 47-64 | Lost 3 |
| » W: Storm Davis (6-7) L: Dennis Powell (0-4) S: Steve Crawford (1) | Sixth | 13 out |
| Saturday, August 11 |
| » Defeated Royals (54-59), 11-5 | Royals Stadium (3-2) | 48-64 | |
| » W: Ron Robinson (8-5) L: Pete Filson (0-4) | Sixth | 13 out |
| Sunday, August 12 |
| » Lost to Royals (55-59), 7-1 | Royals Stadium (3-3) | 48-65 | |
| » W: Tom Gordon (8-8) L: Jaime Navarro (3-4) | Sixth | 14 out |
| Tuesday, August 14 |
| » Defeated Tigers (54-64), 7-6 | Tiger Stadium (4-1) | 49-65 | |
| » W: Chuck Crim (3-4) L: Jerry Don Gleaton (1-3) S: Dan Plesac (17) | Sixth | 13½ out |
| Wednesday, August 15 |
| » Defeated Tigers (54-65), 7-3 | Tiger Stadium (5-1) | 50-65 | Won 2 |
| » W: Paul Mirabella (4-2) L: Steve Searcy (1-5) S: Dan Plesac (18) | Sixth | 12½ out |
| Thursday, August 16 |
| » Defeated Tigers (54-66), 8-4 | Tiger Stadium (6-1) | 51-65 | Won 3 |
| » W: Ron Robinson (9-5) L: Dan Petry (9-9) S: Dan Plesac (19) | Sixth | 12 out |
| Friday, August 17 |
| » Defeated Royals (57-61), 2-1 | County Stadium (25-32) | 52-65 | Won 4 |
| » W: Teddy Higuera (7-5) L: Tom Gordon (8-9) S: Dan Plesac (20) | Sixth | 11 out |
| Saturday, August 18 |
| » Lost to Royals (58-61), 10-1 | County Stadium (25-33) | 52-66 | |
| » W: Kevin Appier (9-4) L: Jaime Navarro (3-5) | Sixth | 11 out |
| Sunday, August 19 |
| » Defeated Royals (58-62), 7-2 | County Stadium (26-33) | 53-66 | |
| » W: Mark Knudson (9-6) L: Andy McGaffigan (3-1) | Sixth | 11 out |
| Monday, August 20 |
| » Defeated Indians (56-65), 4-3 | County Stadium (27-33) | 54-66 | Won 2 |
| » W: Tom Edens (3-1) L: Steve Olin (1-4) S: Chuck Crim (7) | Sixth | 11 out |
| Tuesday, August 21 |
| » Defeated Indians (56-66), 6-5 | County Stadium (28-33) | 55-66 | Won 3 |
| » W: Dan Plesac (3-5) L: Colby Ward (1-1) | Sixth | 10 out |
| Wednesday, August 22 |
| » Lost to Indians (57-66), 4-2 | County Stadium (28-34) | 55-67 | |
| » W: Tom Candiotti (13-8) L: Teddy Higuera (7-6) S: Doug Jones (34) | Sixth | 11 out |
| Thursday, August 23 |
| » Defeated Yankees (52-71), 8-2 | Yankee Stadium (2-2) | 56-67 | |
| » W: Jaime Navarro (4-5) L: Mike Witt (2-6) | Sixth | 10 out |
| Friday, August 24 |
| » Defeated Yankees (52-72), 1-0 | Yankee Stadium (3-2) | 57-67 | Won 2 |
| » W: Mark Knudson (10-6) L: Tim Leary (7-16) S: Dan Plesac (21) | Fourth | 10 out |
| Saturday, August 25 |
| » Defeated Yankees (52-73), 5-3 | Yankee Stadium (4-2) | 58-67 | Won 3 |
| » W: Mark Lee (1-0) L: Dave Righetti (1-1) S: Chuck Crim (8) | Fifth | 10 out |
| Sunday, August 26 |
| » Lost to Yankees (53-73), 4-3 | Yankee Stadium (4-3) | 58-68 | |
| » W: Lee Guetterman (9-4) L: Dan Plesac (3-6) | Sixth | 11 out |
| Monday, August 27 |
| » Defeated Blue Jays (66-63), 4-2 | Skydome (3-1) | 59-68 | |
| » W: Teddy Higuera (8-6) L: Jim Acker (2-4) | Fifth | 11 out |
| Tuesday, August 28 |
| » Defeated Blue Jays (66-64), 6-2 | Skydome (4-1) | 60-68 | Won 2 |
| » W: Jaime Navarro (5-5) L: Dave Stieb (16-5) | Third | 11 out |
| Wednesday, August 29 |
| » Lost to Blue Jays (67-64), 7-3 | Skydome (4-2) | 60-69 | |
| » W: Jimmy Key (9-6) L: Mark Knudson (10-7) S: Duane Ward (10) | Fourth | 12 out |
| Friday, August 31 |
| » Defeated Orioles (60-70), 4-1 | County Stadium (29-34) | 61-69 | |
| » W: Ron Robinson (10-5) L: John Mitchell (6-6) | Fourth | 12½ out |
| Saturday, September 1 |
| » Defeated Orioles (60-71), 4-3 | County Stadium (30-34) | 62-69 | Won 2 |
| » W: Teddy Higuera (9-6) L: Ben McDonald (5-4) S: Dan Plesac (22) | Fourth | 12½ out |
| Sunday, September 2 |
| » Defeated Orioles (60-72), 4-2 | County Stadium (31-34) | 63-69 | Won 3 |
| » W: Jaime Navarro (6-5) L: Jose Mesa (0-2) S: Chuck Crim (9) | Fourth | 12½ out |
| Monday, September 3 |
| » Lost to Twins (61-74), 6-0 | County Stadium (31-35) | 63-70 | |
| » W: Mark Guthrie (6-7) L: Mark Knudson (10-8) | Fourth | 13 out |
| » Lost to Twins (62-74), 9-5 | County Stadium (31-36) | 63-71 | Lost 2 |
| » W: Rick Aguilera (5-3) L: Dan Plesac (3-7) | Fourth | 13 out |
| » Major-league debuts: Tim McIntosh (Brewers) Scott Leius (Twins) |
| Tuesday, September 4 |
| » Lost to Twins (63-74), 7-1 | County Stadium (31-37) | 63-72 | Lost 3 |
| » W: Tim Drummond (3-4) L: Tom Edens (3-2) | Fourth | 13 out |
| Wednesday, September 5 |
| » Defeated Twins (63-75), 7-4 | County Stadium (32-37) | 64-72 | |
| » W: Ron Robinson (11-5) L: Gary Wayne (0-1) | Fourth | 12 out |
| Friday, September 7 |
| » Defeated Tigers (66-73), 6-5 | County Stadium (33-37) | 65-72 | Won 2 |
| » W: Teddy Higuera (10-6) L: Jack Morris (11-17) S: Chuck Crim (10) | Fourth | 12 out |
| » Major-league debuts: Rich Rowland (Tigers) |
| Saturday, September 8 |
| » Defeated Tigers (66-74), 5-2 | County Stadium (34-37) | 66-72 | Won 3 |
| » W: Jaime Navarro (7-5) L: Walt Terrell (6-10) S: Julio Machado (1) | Third | 12 out |
| Sunday, September 9 |
| » Lost to Tigers (67-74), 5-0 | County Stadium (34-38) | 66-73 | |
| » W: Scott Aldred (1-0) L: Bill Krueger (5-8) S: Edwin Nunez (5) | Third | 12 out |
| » Major-league debuts: Narciso Elvira (Brewers) Scott Aldred (Tigers) |
| Monday, September 10 |
| » Lost to Red Sox (79-61), 5-4 | Fenway Park (2-2) | 66-74 | Lost 2 |
| » W: Greg Harris (13-6) L: Mark Knudson (10-9) S: Jeff Gray (9) | Fourth | 12 out |
| » Defeated Red Sox (79-62), 6-1 | Fenway Park (3-2) | 67-74 | |
| » W: Tom Edens (4-2) L: Dana Kiecker (6-8) S: Chuck Crim (11) | Fourth | 12 out |
| Tuesday, September 11 |
| » Defeated Red Sox (79-63), 4-2 | Fenway Park (4-2) | 68-74 | Won 2 |
| » W: Ron Robinson (12-5) L: Wes Gardner (3-7) S: Dan Plesac (23) | Fourth | 11 out |
| Wednesday, September 12 |
| » Lost to Red Sox (80-63), 6-1 | Fenway Park (4-3) | 68-75 | |
| » W: Mike Boddicker (15-8) L: Teddy Higuera (10-7) | Fourth | 12 out |
| Friday, September 14 |
| » Lost to Rangers (76-68), 2-1 | Arlington Stadium (2-2) | 68-76 | Lost 2 |
| » W: Kenny Rogers (9-5) L: Chuck Crim (3-5) | Fourth | 11½ out |
| Saturday, September 15 |
| » Lost to Rangers (77-68), 6-3 | Arlington Stadium (2-3) | 68-77 | Lost 3 |
| » W: Jamie Moyer (2-6) L: Tom Edens (4-3) S: Mike Jeffcoat (5) | Fourth | 11½ out |
| Sunday, September 16 |
| » Defeated Rangers (77-69), 5-3 | Arlington Stadium (3-3) | 69-77 | |
| » W: Ron Robinson (13-5) L: Scott Chiamparino (0-1) S: Julio Machado (2) | Fourth | 10½ out |
| Monday, September 17 |
| » Lost to Indians (68-80), 4-2 | Cleveland Stadium (0-4) | 69-78 | |
| » W: Steve Olin (4-4) L: Teddy Higuera (10-8) S: Doug Jones (36) | Fourth | 11½ out |
| Tuesday, September 18 |
| » Lost to Indians (69-80), 8-3 | Cleveland Stadium (0-5) | 69-79 | Lost 2 |
| » W: Charles Nagy (1-4) L: Don August (0-3) S: Doug Jones (37) | Third | 11½ out |
| Wednesday, September 19 |
| » Lost to Indians (70-80), 6-3 | Cleveland Stadium (0-6) | 69-80 | Lost 3 |
| » W: Sergio Valdez (5-5) L: Jaime Navarro (7-6) S: Doug Jones (38) | Fifth | 12½ out |
| Friday, September 21 |
| » Lost to Orioles (68-81), 5-3 | Memorial Stadium (2-2) | 69-81 | Lost 4 |
| » W: Pete Harnisch (11-11) L: Ron Robinson (13-6) S: Gregg Olson (33) | Fourth | 12½ out |
| Saturday, September 22 |
| » Lost to Orioles (69-81), 3-2 | Memorial Stadium (2-3) | 69-82 | Lost 5 |
| » W: Dave Johnson (12-8) L: Kevin Brown (0-1) S: Kevin Hickey (1) | Fifth | 12½ out |
| Sunday, September 23 |
| » Lost to Orioles (70-81), 2-1 | Memorial Stadium (2-4) | 69-83 | Lost 6 |
| » W: Jeff Ballard (2-10) L: Teddy Higuera (10-9) | Sixth | 13½ out |
| Monday, September 24 |
| » Lost to Blue Jays (84-70), 9-5 | County Stadium (34-39) | 69-84 | Lost 7 |
| » W: Jimmy Key (12-7) L: Jaime Navarro (7-7) S: Tom Henke (31) | Sixth | 14½ out |
| Tuesday, September 25 |
| » Defeated Blue Jays (84-71), 8-4 | County Stadium (35-39) | 70-84 | |
| » W: Bill Krueger (6-8) L: Bud Black (12-11) | Sixth | 13½ out |
| Wednesday, September 26 |
| » Defeated Blue Jays (84-72), 6-0 | County Stadium (36-39) | 71-84 | Won 2 |
| » W: Ron Robinson (14-6) L: David Wells (11-5) | Sixth | 12½ out |
| Thursday, September 27 |
| » Lost to White Sox (91-65), 6-4 | Comiskey Park I (2-4) | 71-85 | |
| » W: Wayne Edwards (5-3) L: Tom Edens (4-4) S: Bobby Thigpen (55) | Fifth | 13 out |
| Friday, September 28 |
| » Lost to Yankees (65-92), 7-2 | County Stadium (36-40) | 71-86 | Lost 2 |
| » W: Steve Adkins (1-1) L: Teddy Higuera (10-10) | Sixth | 14 out |
| Saturday, September 29 |
| » Defeated Yankees (65-93), 8-1 | County Stadium (37-40) | 72-86 | |
| » W: Jaime Navarro (8-7) L: Mike Witt (5-9) | Sixth | 14 out |
| Sunday, September 30 |
| » Lost to Yankees (66-93), 7-2 | County Stadium (37-41) | 72-87 | |
| » W: Dave Eiland (2-1) L: Tom Edens (4-5) S: Greg Cadaret (3) | Sixth | 14 out |
| Monday, October 1 |
| » Lost to Rangers (83-77), 4-2 | County Stadium (37-42) | 72-88 | Lost 2 |
| » W: Mike Jeffcoat (5-6) L: Ron Robinson (14-7) S: Jeff Russell (10) | Sixth | 15 out |
| Tuesday, October 2 |
| » Defeated Rangers (83-78), 1-0 | County Stadium (38-42) | 73-88 | |
| » W: Kevin Brown (1-1) L: Kenny Rogers (10-6) S: Dan Plesac (24) | Sixth | 14 out |
| Wednesday, October 3 |
| » Defeated Rangers (83-79), 6-3 | County Stadium (39-42) | 74-88 | Won 2 |
| » W: Teddy Higuera (11-10) L: John Barfield (4-3) S: Julio Machado (3) | Sixth | 14 out |
Game information provided by Retrosheet (www.retrosheet.org) |