| Saturday, February 10 |
| Former Angel Tony Solaita dies in Tafuna, American Samoa at the age of 44. |
| Saturday, February 24 |
| Former Angel Tony Conigliaro dies in Salem, MA at the age of 46. |
| Monday, April 9 |
| » Lost to Mariners (1-0), 7-4 | Anaheim Stadium (0-1) | 0-1 | |
| » W: Brian Holman (1-0) L: Bert Blyleven (0-1) S: Mike Schooler (1) | Second | 1 out |
| Tuesday, April 10 |
| » Defeated Mariners (1-1), 7-0 | Anaheim Stadium (1-1) | 1-1 | |
| » W: Chuck Finley (1-0) L: Randy Johnson (0-1) S: Mark Eichhorn (1) | Second | 1 out |
| » Major-league debuts: Brent Knackert (Mariners) |
| Wednesday, April 11 |
| » Defeated Mariners (1-2), 1-0 | Anaheim Stadium (2-1) | 2-1 | Won 2 |
| » W: Mark Langston (1-0) L: Gary Eave (0-1) S: Mike Witt (1) | Second | ½ out |
| Thursday, April 12 |
| » Defeated Twins (1-3), 3-1 | Anaheim Stadium (3-1) | 3-1 | Won 3 |
| » W: Kirk McCaskill (1-0) L: David West (0-1) S: Mark Eichhorn (2) | Second | 1 out |
| Friday, April 13 |
| » Lost to Twins (2-3), 7-4 | Anaheim Stadium (3-2) | 3-2 | |
| » W: Allan Anderson (1-1) L: Mike Witt (0-1) S: Rick Aguilera (2) | Third | ½ out |
| Saturday, April 14 |
| » Defeated Twins (2-4), 7-5 | Anaheim Stadium (4-2) | 4-2 | |
| » W: Bryan Harvey (1-0) L: Rick Aguilera (0-1) | Third | ½ out |
| Sunday, April 15 |
| » Defeated Twins (2-5), 4-1 | Anaheim Stadium (5-2) | 5-2 | Won 2 |
| » W: Chuck Finley (2-0) L: Kevin Tapani (1-1) S: Bryan Harvey (1) | Third | ½ out |
| Tuesday, April 17 |
| » Lost to Athletics (6-1), 7-5 | Anaheim Stadium (5-3) | 5-3 | |
| » W: Mike Norris (1-0) L: Mark Eichhorn (0-1) S: Dennis Eckersley (4) | Third | 1½ out |
| Wednesday, April 18 |
| » Lost to Athletics (7-1), 3-1 | Anaheim Stadium (5-4) | 5-4 | Lost 2 |
| » W: Scott Sanderson (2-0) L: Mike Witt (0-2) S: Gene Nelson (1) | Third | 2½ out |
| Friday, April 20 |
| » Lost to Twins (5-6), 13-1 | Hubert H. Humphrey Metrodome (0-1) | 5-5 | Lost 3 |
| » W: Kevin Tapani (2-1) L: Jim Abbott (0-1) | Third | 3 out |
| Saturday, April 21 |
| » Lost to Twins (6-6), 8-0 | Hubert H. Humphrey Metrodome (0-2) | 5-6 | Lost 4 |
| » W: David West (1-2) L: Bert Blyleven (0-2) S: John Candelaria (1) | Fourth | 4 out |
| Sunday, April 22 |
| » Defeated Twins (6-7), 5-2 | Hubert H. Humphrey Metrodome (1-2) | 6-6 | |
| » W: Chuck Finley (3-0) L: Allan Anderson (1-2) S: Mark Eichhorn (3) | Fourth | 3 out |
| Tuesday, April 24 |
| » Lost to Red Sox (7-6), 4-2 | Fenway Park (0-1) | 6-7 | |
| » W: Roger Clemens (4-0) L: Mark Langston (1-1) S: Jeff Reardon (1) | Fifth | 4 out |
| Wednesday, April 25 |
| » Defeated Red Sox (7-7), 3-1 | Fenway Park (1-1) | 7-7 | |
| » W: Kirk McCaskill (2-0) L: Mike Boddicker (1-3) S: Mark Eichhorn (4) | Fourth | 4 out |
| Thursday, April 26 |
| » Lost to Red Sox (8-7), 5-4 | Fenway Park (1-2) | 7-8 | |
| » W: Lee Smith (2-1) L: Bryan Harvey (1-1) | Fourth | 5 out |
| Friday, April 27 |
| » Lost to Yankees (6-8), 5-4 | Yankee Stadium (0-1) | 7-9 | Lost 2 |
| » W: Lee Guetterman (1-1) L: Willie Fraser (0-1) S: Dave Righetti (4) | Fourth | 5 out |
| Saturday, April 28 |
| » Lost to Yankees (7-8), 3-2 | Yankee Stadium (0-2) | 7-10 | Lost 3 |
| » W: Greg Cadaret (1-1) L: Chuck Finley (3-1) S: Dave Righetti (5) | Fifth | 5 out |
| Sunday, April 29 |
| » Defeated Yankees (7-9), 4-3 | Yankee Stadium (1-2) | 8-10 | |
| » W: Mark Langston (2-1) L: Dave LaPoint (1-2) S: Bryan Harvey (2) | Fourth | 5 out |
| Monday, April 30 |
| » Lost to Orioles (9-11), 2-1 | Memorial Stadium (0-1) | 8-11 | |
| » W: Brian Holton (1-0) L: Mike Witt (0-3) | Fourth | 6 out |
| Tuesday, May 1 |
| » Defeated Orioles (9-12), 7-1 | Memorial Stadium (1-1) | 9-11 | |
| » W: Jim Abbott (1-1) L: Jay Tibbs (0-3) | Fourth | 6 out |
| Wednesday, May 2 |
| » Defeated Orioles (9-13), 3-0 | Memorial Stadium (2-1) | 10-11 | Won 2 |
| » W: Bert Blyleven (1-2) L: Jeff Ballard (0-4) S: Mark Eichhorn (5) | Fourth | 6 out |
| Thursday, May 3 |
| » Lost to Mariners (10-13), 10-8 | Kingdome (0-1) | 10-12 | |
| » W: Brent Knackert (1-0) L: Chuck Finley (3-2) S: Mike Schooler (6) | Fourth | 6½ out |
| Friday, May 4 |
| » Lost to Yankees (8-13), 5-2 | Anaheim Stadium (5-5) | 10-13 | Lost 2 |
| » W: Dave LaPoint (2-2) L: Mark Langston (2-2) | Fifth | 7½ out |
| Saturday, May 5 |
| » Lost to Yankees (9-13), 11-3 | Anaheim Stadium (5-6) | 10-14 | Lost 3 |
| » W: Clay Parker (1-1) L: Kirk McCaskill (2-1) | Sixth | 7½ out |
| Sunday, May 6 |
| » Lost to Yankees (10-13), 4-2 | Anaheim Stadium (5-7) | 10-15 | Lost 4 |
| » W: Andy Hawkins (1-3) L: Jim Abbott (1-2) S: Dave Righetti (6) | Sixth | 8½ out |
| Monday, May 7 |
| » Lost to Orioles (11-15), 6-5 | Anaheim Stadium (5-8) | 10-16 | Lost 5 |
| » W: Jay Tibbs (1-3) L: Mark Eichhorn (0-2) S: Gregg Olson (6) | Sixth | 9½ out |
| Tuesday, May 8 |
| » Defeated Orioles (11-16), 6-0 | Anaheim Stadium (6-8) | 11-16 | |
| » W: Chuck Finley (4-2) L: Jeff Ballard (0-5) | Sixth | 9½ out |
| » Major-league debuts: David Segui (Orioles) |
| Wednesday, May 9 |
| » Lost to Orioles (12-16), 9-1 | Anaheim Stadium (6-9) | 11-17 | |
| » W: Pete Harnisch (3-0) L: Mark Langston (2-3) | Sixth | 10½ out |
| Thursday, May 10 |
| » Lost to Mariners (14-16), 5-2 | Kingdome (0-2) | 11-18 | Lost 2 |
| » W: Brian Holman (5-2) L: Kirk McCaskill (2-2) S: Mike Schooler (9) | Sixth | 11 out |
| Friday, May 11 |
| » Lost to Red Sox (16-12), 3-2 | Anaheim Stadium (6-10) | 11-19 | Lost 3 |
| » W: Mike Boddicker (4-3) L: Mark Eichhorn (0-3) S: Jeff Reardon (2) | Fifth | 12 out |
| Saturday, May 12 |
| » Lost to Red Sox (17-12), 7-1 | Anaheim Stadium (6-11) | 11-20 | Lost 4 |
| » W: Greg Harris (4-1) L: Bert Blyleven (1-3) | Sixth | 12 out |
| Sunday, May 13 |
| » Defeated Red Sox (17-13), 8-4 | Anaheim Stadium (7-11) | 12-20 | |
| » W: Chuck Finley (5-2) L: Dennis Lamp (0-1) S: Bryan Harvey (3) | Sixth | 11 out |
| Tuesday, May 15 |
| » Defeated Brewers (17-12), 8-3 | County Stadium (1-0) | 13-20 | Won 2 |
| » W: Mark Langston (3-3) L: Chris Bosio (3-2) | Sixth | 9½ out |
| Wednesday, May 16 |
| » Lost to Brewers (18-12), 13-5 | County Stadium (1-1) | 13-21 | |
| » W: Teddy Higuera (4-1) L: Jim Abbott (1-3) | Sixth | 10½ out |
| Thursday, May 17 |
| » Lost to Brewers (19-12), 6-3 | County Stadium (1-2) | 13-22 | Lost 2 |
| » W: Paul Mirabella (2-0) L: Willie Fraser (0-2) S: Dan Plesac (8) | Sixth | 11 out |
| Friday, May 18 |
| » Defeated Blue Jays (20-17), 4-2 | Skydome (1-0) | 14-22 | |
| » W: Jim Abbott (2-3) L: Dave Stieb (5-2) S: Mark Eichhorn (6) | Sixth | 10 out |
| Saturday, May 19 |
| » Defeated Blue Jays (20-18), 11-9 | Skydome (2-0) | 15-22 | Won 2 |
| » W: Willie Fraser (1-2) L: Duane Ward (1-1) S: Mark Eichhorn (7) | Sixth | 10 out |
| Sunday, May 20 |
| » Lost to Blue Jays (21-18), 5-1 | Skydome (2-1) | 15-23 | |
| » W: Frank Wills (3-1) L: Mark Langston (3-4) S: Tom Henke (4) | Sixth | 10 out |
| Monday, May 21 |
| » Defeated Indians (19-18), 5-3 | Cleveland Stadium (1-0) | 16-23 | |
| » W: Bert Blyleven (2-3) L: Jeff Shaw (1-1) S: Mark Eichhorn (8) | Sixth | 10 out |
| Tuesday, May 22 |
| » Defeated Indians (19-19), 8-3 | Cleveland Stadium (2-0) | 17-23 | Won 2 |
| » W: Chuck Finley (6-2) L: Tom Candiotti (4-2) S: Bryan Harvey (4) | Sixth | 10 out |
| » Major-league debuts: Steve Springer (Indians) |
| Wednesday, May 23 |
| » Defeated Blue Jays (21-21), 5-4 | Anaheim Stadium (8-11) | 18-23 | Won 3 |
| » W: Scott Bailes (1-0) L: Duane Ward (1-2) | Fifth | 10 out |
| Thursday, May 24 |
| » Defeated Blue Jays (21-22), 4-3 | Anaheim Stadium (9-11) | 19-23 | Won 4 |
| » W: Bryan Harvey (2-1) L: Tom Henke (0-1) | Fifth | 10 out |
| Friday, May 25 |
| » Defeated Brewers (22-17), 5-4 | Anaheim Stadium (10-11) | 20-23 | Won 5 |
| » W: Willie Fraser (2-2) L: Tony Fossas (1-3) | Fifth | 10 out |
| Saturday, May 26 |
| » Defeated Brewers (22-18), 10-3 | Anaheim Stadium (11-11) | 21-23 | Won 6 |
| » W: Bert Blyleven (3-3) L: Mark Knudson (3-2) | Fourth | 10 out |
| Sunday, May 27 |
| » Defeated Brewers (22-19), 7-3 | Anaheim Stadium (12-11) | 22-23 | Won 7 |
| » W: Chuck Finley (7-2) L: Bill Wegman (2-2) | Fourth | 9½ out |
| Monday, May 28 |
| » Lost to Indians (21-22), 3-0 | Anaheim Stadium (12-12) | 22-24 | |
| » W: Cecilio Guante (2-2) L: Jim Abbott (2-4) S: Doug Jones (16) | Fourth | 9½ out |
| Tuesday, May 29 |
| » Defeated Indians (21-23), 2-1 | Anaheim Stadium (13-12) | 23-24 | |
| » W: Kirk McCaskill (3-2) L: John Farrell (3-2) S: Mark Eichhorn (9) | Fourth | 8½ out |
| Wednesday, May 30 |
| » Lost to Indians (22-23), 4-2 | Anaheim Stadium (13-13) | 23-25 | |
| » W: Tom Candiotti (5-2) L: Mark Langston (3-5) S: Doug Jones (17) | Fourth | 9½ out |
| Friday, June 1 |
| » Defeated Rangers (19-29), 4-3 | Arlington Stadium (1-0) | 24-25 | |
| » W: Bert Blyleven (4-3) L: Bobby Witt (2-7) S: Mark Eichhorn (10) | Fourth | 10 out |
| Saturday, June 2 |
| » Lost to Rangers (20-29), 6-3 | Arlington Stadium (1-1) | 24-26 | |
| » W: Mike Jeffcoat (1-1) L: Chuck Finley (7-3) | Fourth | 10 out |
| Sunday, June 3 |
| » Defeated Rangers (20-30), 7-4 | Arlington Stadium (2-1) | 25-26 | |
| » W: Jim Abbott (3-4) L: Charlie Hough (5-4) S: Bryan Harvey (5) | Fourth | 9 out |
| Monday, June 4 |
| » Lost to Rangers (21-30), 1-0 | Arlington Stadium (2-2) | 25-27 | |
| » W: Kevin Brown (6-4) L: Kirk McCaskill (3-3) S: Kenny Rogers (1) | Fourth | 9½ out |
| Tuesday, June 5 |
| » Defeated Royals (22-28), 6-4 | Royals Stadium (1-0) | 26-27 | |
| » W: Mark Langston (4-5) L: Richard Dotson (0-4) S: Bryan Harvey (6) | Fourth | 9½ out |
| Wednesday, June 6 |
| » Defeated Royals (22-29), 6-2 | Royals Stadium (2-0) | 27-27 | Won 2 |
| » W: Bert Blyleven (5-3) L: Tom Gordon (2-4) S: Mark Eichhorn (11) | Fourth | 9½ out |
| Thursday, June 7 |
| » Defeated Royals (22-30), 2-1 | Royals Stadium (3-0) | 28-27 | Won 3 |
| » W: Chuck Finley (8-3) L: Bret Saberhagen (5-4) S: Mark Eichhorn (12) | Fourth | 8½ out |
| Friday, June 8 |
| » Lost to Rangers (23-32), 10-6 | Anaheim Stadium (13-14) | 28-28 | |
| » W: Charlie Hough (6-4) L: Mike Fetters (0-1) | Fourth | 9½ out |
| Saturday, June 9 |
| » Defeated Rangers (23-33), 8-3 | Anaheim Stadium (14-14) | 29-28 | |
| » W: Kirk McCaskill (4-3) L: Mike Jeffcoat (1-2) | Fourth | 9½ out |
| Sunday, June 10 |
| » Lost to Rangers (24-33), 2-1 | Anaheim Stadium (14-15) | 29-29 | |
| » W: Kevin Brown (7-4) L: Mark Langston (4-6) | Fourth | 10½ out |
| Monday, June 11 |
| » Defeated Royals (22-34), 3-2 | Anaheim Stadium (15-15) | 30-29 | |
| » W: Bert Blyleven (6-3) L: Mark Davis (1-3) | Fourth | 9½ out |
| Tuesday, June 12 |
| » Defeated Royals (22-35), 3-0 | Anaheim Stadium (16-15) | 31-29 | Won 2 |
| » W: Chuck Finley (9-3) L: Bret Saberhagen (5-5) S: Bryan Harvey (7) | Fourth | 8½ out |
| Wednesday, June 13 |
| » Lost to Royals (23-35), 11-4 | Anaheim Stadium (16-16) | 31-30 | |
| » W: Luis Aquino (2-0) L: Jim Abbott (3-5) | Fourth | 9½ out |
| Friday, June 15 |
| » Lost to Tigers (30-33), 2-1 | Tiger Stadium (0-1) | 31-31 | Lost 2 |
| » W: Jerry Don Gleaton (1-1) L: Bryan Harvey (2-2) | Fourth | 10 out |
| Saturday, June 16 |
| » Lost to Tigers (31-33), 6-2 | Tiger Stadium (0-2) | 31-32 | Lost 3 |
| » W: Jack Morris (6-7) L: Bert Blyleven (6-4) | Fourth | 11 out |
| Sunday, June 17 |
| » Defeated Tigers (31-34), 7-3 | Tiger Stadium (1-2) | 32-32 | |
| » W: Chuck Finley (10-3) L: Brian DuBois (3-5) S: Bryan Harvey (8) | Fourth | 11 out |
| Monday, June 18 |
| » Defeated White Sox (37-24), 4-1 | Comiskey Park I (1-0) | 33-32 | Won 2 |
| » W: Jim Abbott (4-5) L: Jack McDowell (3-4) S: Bryan Harvey (9) | Third | 10 out |
| Tuesday, June 19 |
| » Defeated White Sox (37-25), 5-3 | Comiskey Park I (2-0) | 34-32 | Won 3 |
| » W: Kirk McCaskill (5-3) L: Melido Perez (6-6) S: Mark Eichhorn (13) | Third | 9 out |
| Wednesday, June 20 |
| » Lost to White Sox (38-25), 2-1 | Comiskey Park I (2-1) | 34-33 | |
| » W: Barry Jones (8-1) L: Mark Langston (4-7) S: Bobby Thigpen (22) | Third | 10 out |
| Thursday, June 21 |
| » Defeated Tigers (33-36), 6-4 | Anaheim Stadium (17-16) | 35-33 | |
| » W: Bert Blyleven (7-4) L: Jack Morris (6-8) S: Bryan Harvey (10) | Third | 9½ out |
| Friday, June 22 |
| » Defeated Tigers (33-37), 1-0 | Anaheim Stadium (18-16) | 36-33 | Won 2 |
| » W: Scott Bailes (2-0) L: Paul Gibson (2-2) | Third | 8½ out |
| Saturday, June 23 |
| » Lost to Tigers (34-37), 9-4 | Anaheim Stadium (18-17) | 36-34 | |
| » W: Jeff Robinson (6-5) L: Jim Abbott (4-6) | Third | 8½ out |
| Sunday, June 24 |
| » Defeated Tigers (34-38), 10-2 | Anaheim Stadium (19-17) | 37-34 | |
| » W: Kirk McCaskill (6-3) L: Frank Tanana (5-5) | Third | 7½ out |
| Monday, June 25 |
| » Lost to White Sox (42-25), 2-0 | Anaheim Stadium (19-18) | 37-35 | |
| » W: Greg Hibbard (6-4) L: Mark Langston (4-8) S: Bobby Thigpen (24) | Third | 8½ out |
| Tuesday, June 26 |
| » Lost to White Sox (43-25), 11-9 | Anaheim Stadium (19-19) | 37-36 | Lost 2 |
| » W: Barry Jones (9-1) L: Mark Eichhorn (0-4) S: Bobby Thigpen (25) | Third | 9½ out |
| Wednesday, June 27 |
| » Lost to White Sox (44-25), 5-2 | Anaheim Stadium (19-20) | 37-37 | Lost 3 |
| » W: Eric King (8-1) L: Chuck Finley (10-4) S: Scott Radinsky (3) | Third | 9½ out |
| Friday, June 29 |
| » Defeated Indians (35-37), 7-2 | Cleveland Stadium (3-0) | 38-37 | |
| » W: Jim Abbott (5-6) L: Charles Nagy (0-1) | Third | 9½ out |
| » Major-league debuts: Charles Nagy (Indians) |
| Saturday, June 30 |
| » Lost to Indians (36-37), 4-1 | Cleveland Stadium (3-1) | 38-38 | |
| » W: Tom Candiotti (9-3) L: Kirk McCaskill (6-4) S: Doug Jones (22) | Fourth | 10½ out |
| Sunday, July 1 |
| » Lost to Indians (37-37), 5-3 | Cleveland Stadium (3-2) | 38-39 | Lost 2 |
| » W: Greg Swindell (3-5) L: Mark Langston (4-9) S: Doug Jones (23) | Fourth | 10½ out |
| Monday, July 2 |
| » Defeated Indians (37-38), 2-1 | Cleveland Stadium (4-2) | 39-39 | |
| » W: Chuck Finley (11-4) L: Jesse Orosco (3-4) S: Bryan Harvey (11) | Fourth | 10½ out |
| Tuesday, July 3 |
| » Lost to Blue Jays (43-37), 5-2 | Skydome (2-2) | 39-40 | |
| » W: Todd Stottlemyre (9-7) L: Bert Blyleven (7-5) S: Tom Henke (14) | Fourth | 11½ out |
| Wednesday, July 4 |
| » Lost to Blue Jays (44-37), 4-2 | Skydome (2-3) | 39-41 | Lost 2 |
| » W: John Cerutti (5-6) L: Jim Abbott (5-7) S: Tom Henke (15) | Fourth | 11½ out |
| Thursday, July 5 |
| » Lost to Blue Jays (45-37), 9-2 | Skydome (2-4) | 39-42 | Lost 3 |
| » W: Dave Stieb (11-3) L: Kirk McCaskill (6-5) | Fifth | 11½ out |
| Friday, July 6 |
| » Defeated Brewers (35-43), 9-8 | County Stadium (2-2) | 40-42 | |
| » W: Greg Minton (1-0) L: Tom Edens (1-1) | Fourth | 11 out |
| Saturday, July 7 |
| » Defeated Brewers (35-44), 4-3 | County Stadium (3-2) | 41-42 | Won 2 |
| » W: Mike Fetters (1-1) L: Randy Veres (0-1) | Fourth | 10 out |
| Sunday, July 8 |
| » Lost to Brewers (36-44), 20-7 | County Stadium (3-3) | 41-43 | |
| » W: Tom Edens (2-1) L: Greg Minton (1-1) | Fourth | 11 out |
| Wednesday, July 11 |
| » Lost to Mariners (44-41), 2-1 | Kingdome (0-3) | 41-44 | Lost 2 |
| » W: Erik Hanson (10-6) L: Mark Langston (4-10) S: Mike Schooler (23) | Fourth | 12 out |
| Thursday, July 12 |
| » Lost to Blue Jays (48-38), 5-0 | Anaheim Stadium (19-21) | 41-45 | Lost 3 |
| » W: David Wells (7-2) L: Kirk McCaskill (6-6) | Fifth | 13 out |
| » Major-league debuts: Mark Whiten (Blue Jays) |
| Friday, July 13 |
| » Defeated Blue Jays (48-39), 2-0 | Anaheim Stadium (20-21) | 42-45 | |
| » W: Jim Abbott (6-7) L: Todd Stottlemyre (9-9) | Fifth | 12 out |
| Saturday, July 14 |
| » Defeated Blue Jays (48-40), 8-7 | Anaheim Stadium (21-21) | 43-45 | Won 2 |
| » W: Mark Eichhorn (1-4) L: Duane Ward (1-4) | Fifth | 12 out |
| » Major-league debuts: Cliff Young (Angels) |
| Sunday, July 15 |
| » Defeated Blue Jays (48-41), 3-2 | Anaheim Stadium (22-21) | 44-45 | Won 3 |
| » W: Chuck Finley (12-4) L: Tom Henke (0-2) | Fourth | 12 out |
| Monday, July 16 |
| » Lost to Brewers (39-47), 3-1 | Anaheim Stadium (22-22) | 44-46 | |
| » W: Ron Robinson (5-3) L: Mark Langston (4-11) S: Dan Plesac (15) | Fourth | 13 out |
| » Major-league debuts: Lee Stevens (Angels) |
| Tuesday, July 17 |
| » Defeated Brewers (39-48), 8-1 | Anaheim Stadium (23-22) | 45-46 | |
| » W: Kirk McCaskill (7-6) L: Teddy Higuera (6-4) | Fourth | 12 out |
| Wednesday, July 18 |
| » Lost to Brewers (40-48), 3-2 | Anaheim Stadium (23-23) | 45-47 | |
| » W: Mark Knudson (7-4) L: Jim Abbott (6-8) S: Dan Plesac (16) | Fourth | 13½ out |
| Friday, July 20 |
| » Defeated Indians (44-47), 9-4 | Anaheim Stadium (24-23) | 46-47 | |
| » W: Bert Blyleven (8-5) L: Bud Black (8-5) S: Mike Fetters (1) | Fourth | 12½ out |
| Saturday, July 21 |
| » Defeated Indians (44-48), 5-2 | Anaheim Stadium (25-23) | 47-47 | Won 2 |
| » W: Chuck Finley (13-4) L: Mike Walker (0-1) | Fourth | 11½ out |
| Sunday, July 22 |
| » Lost to Indians (45-48), 8-1 | Anaheim Stadium (25-24) | 47-48 | |
| » W: Greg Swindell (6-5) L: Mark Langston (4-12) | Fourth | 12½ out |
| Monday, July 23 |
| » Lost to Athletics (60-35), 7-6 | Oakland-Alameda County Stadium (0-1) | 47-49 | Lost 2 |
| » W: Gene Nelson (2-2) L: Cliff Young (0-1) | Fifth | 13½ out |
| Tuesday, July 24 |
| » Lost to Athletics (61-35), 5-3 | Oakland-Alameda County Stadium (0-2) | 47-50 | Lost 3 |
| » W: Bob Welch (16-3) L: Jim Abbott (6-9) S: Dennis Eckersley (31) | Fifth | 14½ out |
| Wednesday, July 25 |
| » Lost to Athletics (62-35), 13-3 | Oakland-Alameda County Stadium (0-3) | 47-51 | Lost 4 |
| » W: Curt Young (6-4) L: Bert Blyleven (8-6) S: Todd Burns (2) | Fifth | 15½ out |
| Thursday, July 26 |
| » Defeated Athletics (62-36), 4-2 | Oakland-Alameda County Stadium (1-3) | 48-51 | |
| » W: Bryan Harvey (3-2) L: Dennis Eckersley (2-2) | Fifth | 14½ out |
| Friday, July 27 |
| » Lost to Mariners (52-48), 8-1 | Kingdome (0-4) | 48-52 | |
| » W: Erik Hanson (11-8) L: Mark Langston (4-13) | Fifth | 14½ out |
| Saturday, July 28 |
| » Lost to Mariners (53-48), 2-1 | Kingdome (0-5) | 48-53 | Lost 2 |
| » W: Brian Holman (10-7) L: Kirk McCaskill (7-7) S: Mike Schooler (28) | Fifth | 15 out |
| Sunday, July 29 |
| » Defeated Mariners (53-49), 6-2 | Kingdome (1-5) | 49-53 | |
| » W: Jim Abbott (7-9) L: Matt Young (5-11) S: Bryan Harvey (12) | Fifth | 14 out |
| Monday, July 30 |
| » Lost to Twins (50-53), 7-3 | Hubert H. Humphrey Metrodome (1-3) | 49-54 | |
| » W: Kevin Tapani (11-5) L: Bert Blyleven (8-7) S: Terry Leach (2) | Sixth | 15 out |
| Tuesday, July 31 |
| » Defeated Twins (50-54), 13-2 | Hubert H. Humphrey Metrodome (2-3) | 50-54 | |
| » W: Chuck Finley (14-4) L: Allan Anderson (4-14) | Fifth | 14 out |
| Wednesday, August 1 |
| » Defeated Twins (50-55), 11-5 | Hubert H. Humphrey Metrodome (3-3) | 51-54 | Won 2 |
| » W: Mark Langston (5-13) L: Roy Smith (5-9) S: Bryan Harvey (13) | Fifth | 14 out |
| Thursday, August 2 |
| » Lost to Athletics (66-40), 7-5 | Anaheim Stadium (25-25) | 51-55 | |
| » W: Bob Welch (17-4) L: Kirk McCaskill (7-8) S: Dennis Eckersley (33) | Fifth | 15 out |
| Friday, August 3 |
| » Lost to Athletics (67-40), 8-6 | Anaheim Stadium (25-26) | 51-56 | Lost 2 |
| » W: Reggie Harris (1-0) L: Willie Fraser (2-3) S: Dennis Eckersley (34) | Fifth | 16 out |
| Saturday, August 4 |
| » Defeated Athletics (67-41), 6-5 | Anaheim Stadium (26-26) | 52-56 | |
| » W: Mark Eichhorn (2-4) L: Todd Burns (2-3) | Fifth | 15 out |
| » Major-league debuts: Joe Grahe (Angels) |
| Sunday, August 5 |
| » Lost to Athletics (68-41), 4-1 | Anaheim Stadium (26-27) | 52-57 | |
| » W: Dave Stewart (15-8) L: Chuck Finley (14-5) S: Dennis Eckersley (35) | Fifth | 16 out |
| Monday, August 6 |
| » Major-league debuts: Randy Tomlin (Pirates) |
| Tuesday, August 7 |
| » Lost to Red Sox (59-49), 6-3 | Anaheim Stadium (26-28) | 52-58 | Lost 2 |
| » W: Tom Bolton (6-1) L: Mark Langston (5-14) S: Rob Murphy (7) | Fifth | 17 out |
| Wednesday, August 8 |
| » Defeated Red Sox (59-50), 8-6 | Anaheim Stadium (27-28) | 53-58 | |
| » W: Willie Fraser (3-3) L: Dennis Lamp (3-4) | Fifth | 16 out |
| Thursday, August 9 |
| » Lost to Red Sox (60-50), 14-3 | Anaheim Stadium (27-29) | 53-59 | |
| » W: Roger Clemens (16-5) L: Jim Abbott (7-10) | Sixth | 17 out |
| Friday, August 10 |
| » Defeated Orioles (54-57), 2-1 | Anaheim Stadium (28-29) | 54-59 | |
| » W: Willie Fraser (4-3) L: Gregg Olson (5-4) | Fifth | 17 out |
| Saturday, August 11 |
| » Defeated Orioles (54-58), 12-4 | Anaheim Stadium (29-29) | 55-59 | Won 2 |
| » W: Chuck Finley (15-5) L: Mickey Weston (0-1) | Fifth | 17 out |
| Sunday, August 12 |
| » Lost to Orioles (55-58), 11-6 | Anaheim Stadium (29-30) | 55-60 | |
| » W: John Mitchell (5-4) L: Mark Langston (5-15) S: Mark Williamson (1) | Sixth | 18 out |
| Monday, August 13 |
| » Defeated Yankees (46-68), 4-2 | Anaheim Stadium (30-30) | 56-60 | |
| » W: Kirk McCaskill (8-8) L: Chuck Cary (4-8) S: Bryan Harvey (14) | Sixth | 18 out |
| Tuesday, August 14 |
| » Defeated Yankees (46-69), 9-5 | Anaheim Stadium (31-30) | 57-60 | Won 2 |
| » W: Jim Abbott (8-10) L: Tim Leary (6-15) S: Willie Fraser (1) | Sixth | 17 out |
| Wednesday, August 15 |
| » Defeated Yankees (46-70), 8-1 | Anaheim Stadium (32-30) | 58-60 | Won 3 |
| » W: Mark Langston (6-15) L: Dave LaPoint (6-9) | Fifth | 17 out |
| Friday, August 17 |
| » Defeated Red Sox (63-54), 1-0 | Fenway Park (2-2) | 59-60 | Won 4 |
| » W: Chuck Finley (16-5) L: Mike Boddicker (11-8) | Fifth | 17 out |
| Saturday, August 18 |
| » Defeated Red Sox (63-55), 4-3 | Fenway Park (3-2) | 60-60 | Won 5 |
| » W: Kirk McCaskill (9-8) L: Tom Bolton (7-2) S: Bryan Harvey (15) | Fourth | 17 out |
| » Major-league debuts: Pete Coachman (Angels) |
| Sunday, August 19 |
| » Lost to Red Sox (64-55), 4-1 | Fenway Park (3-3) | 60-61 | |
| » W: Roger Clemens (18-5) L: Jim Abbott (8-11) S: Jeff Gray (3) | Fourth | 17 out |
| Monday, August 20 |
| » Defeated Tigers (56-67), 5-3 | Tiger Stadium (2-2) | 61-61 | |
| » W: Mark Langston (7-15) L: Paul Gibson (3-3) S: Bryan Harvey (16) | Fourth | 16 out |
| Tuesday, August 21 |
| » Lost to Tigers (57-67), 6-2 | Tiger Stadium (2-3) | 61-62 | |
| » W: Dan Petry (10-9) L: Joe Grahe (0-1) S: Edwin Nunez (4) | Fourth | 16 out |
| Wednesday, August 22 |
| » Lost to Tigers (58-67), 7-4 | Tiger Stadium (2-4) | 61-63 | Lost 2 |
| » W: Jack Morris (11-15) L: Chuck Finley (16-6) S: Jerry Don Gleaton (8) | Fifth | 17 out |
| Thursday, August 23 |
| » Lost to White Sox (72-50), 4-2 | Comiskey Park I (2-2) | 61-64 | Lost 3 |
| » W: Alex Fernandez (2-1) L: Kirk McCaskill (9-9) S: Bobby Thigpen (42) | Fifth | 17½ out |
| Friday, August 24 |
| » Lost to White Sox (73-50), 5-2 | Comiskey Park I (2-3) | 61-65 | Lost 4 |
| » W: Wayne Edwards (3-2) L: Jim Abbott (8-12) S: Bobby Thigpen (43) | Fifth | 18½ out |
| Saturday, August 25 |
| » Defeated White Sox (73-51), 3-2 | Comiskey Park I (3-3) | 62-65 | |
| » W: Mark Langston (8-15) L: Bobby Thigpen (4-6) S: Bryan Harvey (17) | Fifth | 17½ out |
| Sunday, August 26 |
| » Defeated White Sox (73-52), 4-1 | Comiskey Park I (4-3) | 63-65 | Won 2 |
| » W: Joe Grahe (1-1) L: Greg Hibbard (10-8) S: Bryan Harvey (18) | Fifth | 16½ out |
| Monday, August 27 |
| » Defeated Rangers (66-62), 7-3 | Anaheim Stadium (33-30) | 64-65 | Won 3 |
| » W: Willie Fraser (5-3) L: John Barfield (3-1) S: Bryan Harvey (19) | Fifth | 16 out |
| Tuesday, August 28 |
| » Defeated Rangers (66-63), 2-0 | Anaheim Stadium (34-30) | 65-65 | Won 4 |
| » W: Kirk McCaskill (10-9) L: Nolan Ryan (12-7) | Fifth | 16 out |
| Wednesday, August 29 |
| » Defeated Rangers (66-64), 9-2 | Anaheim Stadium (35-30) | 66-65 | Won 5 |
| » W: Jim Abbott (9-12) L: John Barfield (3-2) | Fourth | 15 out |
| Friday, August 31 |
| » Lost to White Sox (75-55), 6-5 | Anaheim Stadium (35-31) | 66-66 | |
| » W: Greg Hibbard (11-8) L: Mark Langston (8-16) S: Bobby Thigpen (45) | Fourth | 16½ out |
| Saturday, September 1 |
| » Lost to White Sox (76-55), 9-5 | Anaheim Stadium (35-32) | 66-67 | Lost 2 |
| » W: Melido Perez (12-12) L: Joe Grahe (1-2) S: Bobby Thigpen (46) | Fourth | 16½ out |
| Sunday, September 2 |
| » Defeated White Sox (76-56), 1-0 | Anaheim Stadium (36-32) | 67-67 | |
| » W: Chuck Finley (17-6) L: Alex Fernandez (2-2) S: Bryan Harvey (20) | Fourth | 16½ out |
| Monday, September 3 |
| » Defeated Yankees (56-78), 7-0 | Yankee Stadium (2-2) | 68-67 | Won 2 |
| » W: Kirk McCaskill (11-9) L: Tim Leary (8-17) S: Willie Fraser (2) | Fourth | 16½ out |
| Tuesday, September 4 |
| » Major-league debuts: Tom Quinlan (Blue Jays) |
| Wednesday, September 5 |
| » Lost to Yankees (57-78), 2-1 | Yankee Stadium (2-3) | 68-68 | |
| » W: Dave LaPoint (7-10) L: Bryan Harvey (3-3) S: Dave Righetti (30) | Fourth | 18 out |
| Thursday, September 6 |
| » Defeated Yankees (57-79), 12-6 | Yankee Stadium (3-3) | 69-68 | |
| » W: Bob McClure (1-0) L: Lee Guetterman (9-5) | Fourth | 17½ out |
| Friday, September 7 |
| » Lost to Orioles (61-75), 6-2 | Memorial Stadium (2-2) | 69-69 | |
| » W: Ben McDonald (6-4) L: Joe Grahe (1-3) | Fourth | 18½ out |
| Saturday, September 8 |
| » Lost to Orioles (62-75), 5-4 | Memorial Stadium (2-3) | 69-70 | Lost 2 |
| » W: Joe Price (3-3) L: Mark Eichhorn (2-5) | Fourth | 19½ out |
| Sunday, September 9 |
| » Lost to Orioles (63-75), 3-1 | Memorial Stadium (2-4) | 69-71 | Lost 3 |
| » W: Anthony Telford (2-2) L: Kirk McCaskill (11-10) S: Gregg Olson (30) | Fourth | 20½ out |
| Monday, September 10 |
| » Defeated Twins (65-77), 3-1 | Anaheim Stadium (37-32) | 70-71 | |
| » W: Jim Abbott (10-12) L: Paul Abbott (0-3) S: Bryan Harvey (21) | Fourth | 19½ out |
| Tuesday, September 11 |
| » Defeated Twins (65-78), 9-0 | Anaheim Stadium (38-32) | 71-71 | Won 2 |
| » W: Mark Langston (9-16) L: Kevin Tapani (11-7) | Fourth | 19½ out |
| Wednesday, September 12 |
| » Defeated Twins (65-79), 8-6 | Anaheim Stadium (39-32) | 72-71 | Won 3 |
| » W: Joe Grahe (2-3) L: Tim Drummond (3-5) S: Bryan Harvey (22) | Fourth | 19½ out |
| Thursday, September 13 |
| » Defeated Mariners (70-74), 7-1 | Anaheim Stadium (40-32) | 73-71 | Won 4 |
| » W: Chuck Finley (18-6) L: Keith Comstock (7-4) | Fourth | 18½ out |
| Friday, September 14 |
| » Defeated Mariners (70-75), 7-5 | Anaheim Stadium (41-32) | 74-71 | Won 5 |
| » W: Bob McClure (2-0) L: Matt Young (8-15) S: Bryan Harvey (23) | Fourth | 18½ out |
| Saturday, September 15 |
| » Lost to Mariners (71-75), 7-2 | Anaheim Stadium (41-33) | 74-72 | |
| » W: Erik Hanson (15-9) L: Jim Abbott (10-13) | Fourth | 19½ out |
| Sunday, September 16 |
| » Lost to Mariners (72-75), 5-3 | Anaheim Stadium (41-34) | 74-73 | Lost 2 |
| » W: Bill Swift (6-4) L: Bryan Harvey (3-4) S: Mike Jackson (3) | Fourth | 20½ out |
| Monday, September 17 |
| » Major-league debuts: Leo Gomez (Orioles) |
| Tuesday, September 18 |
| » Lost to Tigers (72-77), 3-2 | Anaheim Stadium (41-35) | 74-74 | Lost 3 |
| » W: Jack Morris (12-18) L: Chuck Finley (18-7) S: Mike Henneman (21) | Fourth | |