| Tuesday, April 4 |
| » Lost to Rangers (1-0), 4-0 | Arlington Stadium (0-1) | 0-1 | |
| » W: Charlie Hough (1-0) L: Jack Morris (0-1) | Second | 1 out |
| Thursday, April 6 |
| » Lost to Rangers (2-0), 5-4 | Arlington Stadium (0-2) | 0-2 | Lost 2 |
| » W: Cecilio Guante (1-0) L: Frank Williams (0-1) S: Jeff Russell (1) | Fourth | 2 out |
| » Major-league debuts: Kenny Rogers (Rangers) |
| Friday, April 7 |
| » Defeated Brewers (1-2), 10-3 | Tiger Stadium (1-0) | 1-2 | |
| » W: Doyle Alexander (1-0) L: Bill Wegman (0-1) S: Willie Hernandez (1) | Third | 1 out |
| » Major-league debuts: Bill Spiers (Brewers) |
| Saturday, April 8 |
| » Lost to Brewers (2-2), 5-2 | Tiger Stadium (1-1) | 1-3 | |
| » W: Don August (1-1) L: Frank Tanana (0-1) S: Dan Plesac (1) | Fourth | 2 out |
| Tuesday, April 11 |
| » Lost to Twins (5-2), 14-0 | Tiger Stadium (1-2) | 1-4 | Lost 2 |
| » W: Allan Anderson (2-0) L: Jack Morris (0-2) | Sixth | 2½ out |
| Thursday, April 13 |
| » Defeated Twins (5-3), 3-0 | Tiger Stadium (2-2) | 2-4 | |
| » W: Jeff Robinson (1-0) L: Shane Rawley (1-1) | Fifth | 2 out |
| Friday, April 14 |
| » Lost to Rangers (8-1), 4-2 | Tiger Stadium (2-3) | 2-5 | |
| » W: Jamie Moyer (2-0) L: Frank Williams (0-2) S: Jeff Russell (3) | Sixth | 2 out |
| Saturday, April 15 |
| » Lost to Rangers (9-1), 4-1 | Tiger Stadium (2-4) | 2-6 | Lost 2 |
| » W: Kevin Brown (1-0) L: Frank Tanana (0-2) | Sixth | 2 out |
| Sunday, April 16 |
| » Lost to Rangers (10-1), 9-6 | Tiger Stadium (2-5) | 2-7 | Lost 3 |
| » W: Charlie Hough (2-0) L: Jack Morris (0-3) S: Jeff Russell (4) | Sixth | 2½ out |
| Tuesday, April 18 |
| » Lost to Twins (7-4), 9-8 | Hubert H. Humphrey Metrodome (0-1) | 2-8 | Lost 4 |
| » W: Freddie Toliver (1-0) L: Jeff Robinson (1-1) S: Jeff Reardon (2) | Sixth | 3 out |
| Wednesday, April 19 |
| » Defeated Twins (7-5), 3-2 | Hubert H. Humphrey Metrodome (1-1) | 3-8 | |
| » W: Doyle Alexander (2-0) L: Frank Viola (0-3) S: Willie Hernandez (2) | Sixth | 2½ out |
| Thursday, April 20 |
| » Lost to Twins (8-5), 7-2 | Hubert H. Humphrey Metrodome (1-2) | 3-9 | |
| » W: German Gonzalez (2-0) L: Frank Tanana (0-3) | Seventh | 3½ out |
| Friday, April 21 |
| » Lost to Brewers (7-7), 2-1 | County Stadium (0-1) | 3-10 | Lost 2 |
| » W: Chris Bosio (3-0) L: Jack Morris (0-4) S: Dan Plesac (4) | Sixth | 3½ out |
| Saturday, April 22 |
| » Defeated Brewers (7-8), 6-3 | County Stadium (1-1) | 4-10 | |
| » W: Frank Williams (1-2) L: Chuck Crim (1-2) | Fifth | 3 out |
| Sunday, April 23 |
| » Defeated Brewers (7-9), 11-3 | County Stadium (2-1) | 5-10 | Won 2 |
| » W: Paul Gibson (1-0) L: Don August (1-4) S: Willie Hernandez (3) | Fifth | 3 out |
| Monday, April 24 |
| » Defeated Mariners (8-12), 1-0 | Tiger Stadium (3-5) | 6-10 | Won 3 |
| » W: Doyle Alexander (3-0) L: Mark Langston (2-3) | Seventh | 2 out |
| Tuesday, April 25 |
| » Defeated Mariners (8-13), 5-2 | Tiger Stadium (4-5) | 7-10 | Won 4 |
| » W: Frank Tanana (1-3) L: Scott Bankhead (1-2) S: Willie Hernandez (4) | Fifth | 2 out |
| Wednesday, April 26 |
| » Lost to Angels (11-10), 1-0 | Anaheim Stadium (0-1) | 7-11 | |
| » W: Chuck Finley (3-2) L: Jack Morris (0-5) S: Bryan Harvey (4) | Fifth | 3 out |
| Thursday, April 27 |
| » Lost to Angels (12-10), 10-3 | Anaheim Stadium (0-2) | 7-12 | Lost 2 |
| » W: Bert Blyleven (3-1) L: Charles Hudson (0-1) | Sixth | 3 out |
| » Major-league debuts: Ramon Pena (Tigers) |
| Friday, April 28 |
| » Lost to Athletics (17-7), 2-1 | Oakland-Alameda County Stadium (0-1) | 7-13 | Lost 3 |
| » W: Mike Moore (3-1) L: Paul Gibson (1-1) S: Dennis Eckersley (8) | Seventh | 3 out |
| Saturday, April 29 |
| » Lost to Athletics (18-7), 3-2 | Oakland-Alameda County Stadium (0-2) | 7-14 | Lost 4 |
| » W: Dave Stewart (5-0) L: Doyle Alexander (3-1) | Fifth | 3 out |
| Sunday, April 30 |
| » Defeated Athletics (18-8), 7-2 | Oakland-Alameda County Stadium (1-2) | 8-14 | |
| » W: Frank Tanana (2-3) L: Storm Davis (2-2) S: Willie Hernandez (5) | Fourth | 3 out |
| Monday, May 1 |
| » Lost to Mariners (12-15), 5-3 | Kingdome (0-1) | 8-15 | |
| » W: Dennis Powell (1-0) L: Jack Morris (0-6) S: Mike Schooler (3) | Fifth | 3½ out |
| Tuesday, May 2 |
| » Lost to Mariners (13-15), 7-2 | Kingdome (0-2) | 8-16 | Lost 2 |
| » W: Mike Dunne (2-2) L: Charles Hudson (0-2) S: Mike Jackson (2) | Seventh | 4½ out |
| Wednesday, May 3 |
| » Lost to Mariners (14-15), 3-2 | Kingdome (0-3) | 8-17 | Lost 3 |
| » W: Erik Hanson (3-2) L: Doyle Alexander (3-2) S: Mike Schooler (4) | Seventh | 5 out |
| Friday, May 5 |
| » Lost to Athletics (20-9), 5-3 | Tiger Stadium (4-6) | 8-18 | Lost 4 |
| » W: Dave Stewart (6-0) L: Frank Tanana (2-4) S: Dennis Eckersley (9) | Seventh | 5½ out |
| Saturday, May 6 |
| » Defeated Athletics (20-10), 6-3 | Tiger Stadium (5-6) | 9-18 | |
| » W: Jack Morris (1-6) L: Storm Davis (2-3) S: Willie Hernandez (6) | Fifth | 5½ out |
| Sunday, May 7 |
| » Lost to Athletics (21-10), 5-4 | Tiger Stadium (5-7) | 9-19 | |
| » W: Bob Welch (4-2) L: Charles Hudson (0-3) S: Dennis Eckersley (10) | Seventh | 6½ out |
| Monday, May 8 |
| » Lost to Angels (20-11), 9-2 | Tiger Stadium (5-8) | 9-20 | Lost 2 |
| » W: Chuck Finley (4-2) L: Doyle Alexander (3-3) | Seventh | 6½ out |
| Tuesday, May 9 |
| » Lost to Angels (21-11), 5-1 | Tiger Stadium (5-9) | 9-21 | Lost 3 |
| » W: Bert Blyleven (4-1) L: Paul Gibson (1-2) | Seventh | 6½ out |
| Wednesday, May 10 |
| » Defeated Angels (21-12), 3-2 | Tiger Stadium (6-9) | 10-21 | |
| » W: Willie Hernandez (1-0) L: Bryan Harvey (1-1) | Seventh | 6 out |
| Friday, May 12 |
| » Defeated Indians (15-17), 6-3 | Cleveland Stadium (1-0) | 11-21 | Won 2 |
| » W: Jack Morris (2-6) L: Bud Black (1-5) | Sixth | 6 out |
| Saturday, May 13 |
| » Lost to Indians (16-17), 3-1 | Cleveland Stadium (1-1) | 11-22 | |
| » W: Greg Swindell (4-0) L: Doyle Alexander (3-4) | Seventh | 6 out |
| Sunday, May 14 |
| » Lost to Indians (17-17), 8-3 | Cleveland Stadium (1-2) | 11-23 | Lost 2 |
| » W: Tom Candiotti (4-2) L: Paul Gibson (1-3) | Fifth | 6 out |
| Monday, May 15 |
| » Defeated White Sox (16-21), 3-2 | Tiger Stadium (7-9) | 12-23 | |
| » W: Frank Tanana (3-4) L: Bill Long (2-4) S: Willie Hernandez (7) | Seventh | 5½ out |
| Tuesday, May 16 |
| » Defeated White Sox (16-22), 9-7 | Tiger Stadium (8-9) | 13-23 | Won 2 |
| » W: Frank Williams (2-2) L: Melido Perez (2-4) | Seventh | 4½ out |
| Wednesday, May 17 |
| » Lost to White Sox (17-22), 10-7 | Tiger Stadium (8-10) | 13-24 | |
| » W: Ken Patterson (2-0) L: Willie Hernandez (1-1) S: Shawn Hillegas (1) | Seventh | 5 out |
| Friday, May 19 |
| » Defeated Royals (25-15), 2-0 | Tiger Stadium (9-10) | 14-24 | |
| » W: Mike Henneman (1-0) L: Bret Saberhagen (3-4) | Seventh | 5 out |
| Saturday, May 20 |
| » Defeated Royals (25-16), 2-1 | Tiger Stadium (10-10) | 15-24 | Won 2 |
| » W: Mike Henneman (2-0) L: Tom Gordon (4-2) | Seventh | 4 out |
| Sunday, May 21 |
| » Defeated Royals (25-17), 4-2 | Tiger Stadium (11-10) | 16-24 | Won 3 |
| » W: Paul Gibson (2-3) L: Mark Gubicza (3-4) S: Willie Hernandez (8) | Seventh | 3½ out |
| Monday, May 22 |
| » Lost to Indians (21-21), 7-3 | Tiger Stadium (11-11) | 16-25 | |
| » W: Bud Black (3-5) L: Jack Morris (2-7) S: Jesse Orosco (1) | Sixth | 4½ out |
| Tuesday, May 23 |
| » Defeated Indians (21-22), 7-2 | Tiger Stadium (12-11) | 17-25 | |
| » W: Mike Trujillo (1-0) L: Greg Swindell (4-1) | Sixth | 3½ out |
| Wednesday, May 24 |
| » Defeated Indians (21-23), 2-1 | Tiger Stadium (13-11) | 18-25 | Won 2 |
| » W: Willie Hernandez (2-1) L: Scott Bailes (1-2) | Fourth | 3½ out |
| Thursday, May 25 |
| » Defeated Indians (21-24), 9-5 | Tiger Stadium (14-11) | 19-25 | Won 3 |
| » W: Frank Tanana (4-4) L: John Farrell (2-5) S: Willie Hernandez (9) | Fifth | 3½ out |
| Friday, May 26 |
| » Lost to Royals (27-19), 6-3 | Royals Stadium (0-1) | 19-26 | |
| » W: Jeff Montgomery (6-1) L: Mike Henneman (2-1) S: Steve Farr (11) | Fifth | 4 out |
| Saturday, May 27 |
| » Lost to Royals (28-19), 5-1 | Royals Stadium (0-2) | 19-27 | Lost 2 |
| » W: Mark Gubicza (4-4) L: Randy Nosek (0-1) | Sixth | 5 out |
| Sunday, May 28 |
| » Lost to Royals (29-19), 9-5 | Royals Stadium (0-3) | 19-28 | Lost 3 |
| » W: Tom Gordon (5-2) L: Mike Trujillo (1-1) | Sixth | 5 out |
| Monday, May 29 |
| » Defeated White Sox (18-31), 4-2 | Comiskey Park I (1-0) | 20-28 | |
| » W: Doyle Alexander (4-4) L: Eric King (4-6) S: Willie Hernandez (10) | Sixth | 5 out |
| Tuesday, May 30 |
| » Defeated White Sox (18-32), 10-3 | Comiskey Park I (2-0) | 21-28 | Won 2 |
| » W: Frank Tanana (5-4) L: Jeff Bittiger (0-1) S: Frank Williams (1) | Fifth | 5 out |
| Wednesday, May 31 |
| » Defeated White Sox (18-33), 4-3 | Comiskey Park I (3-0) | 22-28 | Won 3 |
| » W: Mike Henneman (3-1) L: Bobby Thigpen (0-2) S: Willie Hernandez (11) | Fifth | 5 out |
| » Major-league debuts: Greg Hibbard (White Sox) |
| Thursday, June 1 |
| » Lost to Orioles (27-22), 8-3 | Tiger Stadium (14-12) | 22-29 | |
| » W: Dave Schmidt (5-4) L: Randy Nosek (0-2) S: Mark Thurmond (1) | Fifth | 6 out |
| Friday, June 2 |
| » Lost to Orioles (28-22), 4-1 | Tiger Stadium (14-13) | 22-30 | Lost 2 |
| » W: Bob Milacki (3-5) L: Mike Trujillo (1-2) S: Kevin Hickey (2) | Sixth | 7 out |
| Saturday, June 3 |
| » Lost to Orioles (29-22), 4-2 | Tiger Stadium (14-14) | 22-31 | Lost 3 |
| » W: Kevin Hickey (1-0) L: Doyle Alexander (4-5) S: Gregg Olson (6) | Fifth | 8 out |
| Sunday, June 4 |
| » Lost to Orioles (30-22), 7-4 | Tiger Stadium (14-15) | 22-32 | Lost 4 |
| » W: Jay Tibbs (2-0) L: Frank Tanana (5-5) S: Mark Williamson (6) | Seventh | 9 out |
| Monday, June 5 |
| » Lost to Red Sox (25-27), 5-2 | Tiger Stadium (14-16) | 22-33 | Lost 5 |
| » W: Roger Clemens (6-4) L: David Palmer (0-1) S: Rob Murphy (2) | Sixth | 10 out |
| Tuesday, June 6 |
| » Defeated Red Sox (25-28), 5-1 | Tiger Stadium (15-16) | 23-33 | |
| » W: Mike Schwabe (1-0) L: Joe Price (1-2) S: Willie Hernandez (12) | Fifth | 9 out |
| Wednesday, June 7 |
| » Lost to Red Sox (26-28), 6-1 | Tiger Stadium (15-17) | 23-34 | |
| » W: John Dopson (6-4) L: Doyle Alexander (4-6) | Seventh | 9½ out |
| Friday, June 9 |
| » Lost to Blue Jays (25-33), 2-0 | Skydome (0-1) | 23-35 | Lost 2 |
| » W: Dave Stieb (5-3) L: Frank Tanana (5-6) S: David Wells (1) | Seventh | 10 out |
| Saturday, June 10 |
| » Defeated Blue Jays (25-34), 11-8 | Skydome (1-1) | 24-35 | |
| » W: Frank Williams (3-2) L: Jimmy Key (6-5) | Seventh | 9 out |
| Sunday, June 11 |
| » Lost to Blue Jays (26-34), 4-0 | Skydome (1-2) | 24-36 | |
| » W: Mike Flanagan (4-5) L: Mike Schwabe (1-1) S: Duane Ward (5) | Sixth | 9 out |
| Monday, June 12 |
| » Lost to Blue Jays (27-34), 5-4 | Skydome (1-3) | 24-37 | Lost 2 |
| » W: Tom Henke (4-3) L: Paul Gibson (2-4) | Sixth | 9½ out |
| Tuesday, June 13 |
| » Lost to Red Sox (28-31), 8-7 | Fenway Park (0-1) | 24-38 | Lost 3 |
| » W: Wes Gardner (2-4) L: Frank Williams (3-3) S: Lee Smith (6) | Seventh | 10½ out |
| Wednesday, June 14 |
| » Defeated Red Sox (28-32), 7-3 | Fenway Park (1-1) | 25-38 | |
| » W: Frank Tanana (6-6) L: Mike Boddicker (3-6) | Sixth | 9½ out |
| Friday, June 16 |
| » Lost to Angels (37-26), 9-4 | Tiger Stadium (15-18) | 25-39 | |
| » W: Bert Blyleven (7-2) L: Mike Schwabe (1-2) S: Bryan Harvey (7) | Sixth | 10½ out |
| Saturday, June 17 |
| » Lost to Angels (38-26), 6-3 | Tiger Stadium (15-19) | 25-40 | Lost 2 |
| » W: Jim Abbott (6-4) L: Doyle Alexander (4-7) S: Bob McClure (3) | Sixth | 11½ out |
| Sunday, June 18 |
| » Lost to Angels (39-26), 3-1 | Tiger Stadium (15-20) | 25-41 | Lost 3 |
| » W: Mike Witt (4-7) L: David Palmer (0-2) S: Bryan Harvey (8) | Fifth | 12½ out |
| Monday, June 19 |
| » Defeated Athletics (42-27), 6-4 | Oakland-Alameda County Stadium (2-2) | 26-41 | |
| » W: Frank Tanana (7-6) L: Dave Stewart (11-3) S: Mike Henneman (1) | Fifth | 12½ out |
| Tuesday, June 20 |
| » Lost to Athletics (43-27), 6-4 | Oakland-Alameda County Stadium (2-3) | 26-42 | |
| » W: Gene Nelson (2-2) L: Brad Havens (0-1) S: Todd Burns (4) | Sixth | 13½ out |
| Wednesday, June 21 |
| » Lost to Athletics (44-27), 6-3 | Oakland-Alameda County Stadium (2-4) | 26-43 | Lost 2 |
| » W: Mike Moore (9-5) L: Mike Schwabe (1-3) S: Rick Honeycutt (7) | Sixth | 14½ out |
| Friday, June 23 |
| » Defeated Mariners (32-41), 5-4 | Kingdome (1-3) | 27-43 | |
| » W: Mike Henneman (4-1) L: Mike Schooler (1-2) | Seventh | 14 out |
| Saturday, June 24 |
| » Lost to Mariners (33-41), 3-1 | Kingdome (1-4) | 27-44 | |
| » W: Scott Bankhead (5-4) L: Frank Tanana (7-7) S: Mike Schooler (15) | Seventh | 14 out |
| Sunday, June 25 |
| » Lost to Mariners (34-41), 5-3 | Kingdome (1-5) | 27-45 | Lost 2 |
| » W: Bill Swift (3-2) L: David Palmer (0-3) S: Mike Jackson (4) | Seventh | 14 out |
| Tuesday, June 27 |
| » Defeated Yankees (36-38), 6-5 | Tiger Stadium (16-20) | 28-45 | |
| » W: Brad Havens (1-1) L: Lee Guetterman (1-1) | Seventh | 14 out |
| Wednesday, June 28 |
| » Defeated Yankees (36-39), 6-5 | Tiger Stadium (17-20) | 29-45 | Won 2 |
| » W: Mike Henneman (5-1) L: Dave Righetti (2-2) | Sixth | 14 out |
| Thursday, June 29 |
| » Lost to Yankees (37-39), 7-6 | Tiger Stadium (17-21) | 29-46 | |
| » W: Eric Plunk (2-1) L: Edwin Nunez (0-1) S: Dave Righetti (14) | Seventh | 14 out |
| Friday, June 30 |
| » Defeated Orioles (43-33), 16-5 | Memorial Stadium (1-0) | 30-46 | |
| » W: Mike Schwabe (2-3) L: Bob Milacki (4-8) | Seventh | 13 out |
| » Major-league debuts: Mike Smith (Orioles) |
| Saturday, July 1 |
| » Lost to Orioles (44-33), 8-1 | Memorial Stadium (1-1) | 30-47 | |
| » W: Jeff Ballard (10-3) L: Charles Hudson (0-4) | Seventh | 14 out |
| Sunday, July 2 |
| » Defeated Orioles (44-34), 7-3 | Memorial Stadium (2-1) | 31-47 | |
| » W: Edwin Nunez (1-1) L: Mark Thurmond (2-2) S: Mike Henneman (2) | Seventh | 13 out |
| Monday, July 3 |
| » Lost to Orioles (45-34), 11-4 | Memorial Stadium (2-2) | 31-48 | |
| » W: Mike Smith (1-0) L: Doyle Alexander (4-8) | Seventh | 14 out |
| Tuesday, July 4 |
| » Lost to Yankees (40-41), 1-0 | Yankee Stadium (0-1) | 31-49 | Lost 2 |
| » W: Don Schulze (1-0) L: Frank Tanana (7-8) S: Lee Guetterman (10) | Seventh | 15 out |
| Wednesday, July 5 |
| » Lost to Yankees (41-41), 9-0 | Yankee Stadium (0-2) | 31-50 | Lost 3 |
| » W: Andy Hawkins (10-8) L: Brad Havens (1-2) | Seventh | 16 out |
| Thursday, July 6 |
| » Lost to Yankees (42-41), 6-5 | Yankee Stadium (0-3) | 31-51 | Lost 4 |
| » W: Eric Plunk (3-1) L: Mike Henneman (5-2) | Seventh | 16 out |
| Friday, July 7 |
| » Lost to Blue Jays (40-45), 6-4 | Tiger Stadium (17-22) | 31-52 | Lost 5 |
| » W: Steve Cummings (2-0) L: Willie Hernandez (2-2) S: Tom Henke (4) | Seventh | 16 out |
| Saturday, July 8 |
| » Lost to Blue Jays (41-45), 8-3 | Tiger Stadium (17-23) | 31-53 | Lost 6 |
| » W: John Cerutti (5-4) L: Doyle Alexander (4-9) S: Duane Ward (8) | Sixth | 17 out |
| Sunday, July 9 |
| » Lost to Blue Jays (42-45), 2-0 | Tiger Stadium (17-24) | 31-54 | Lost 7 |
| » W: Dave Stieb (8-5) L: Frank Tanana (7-9) S: Tom Henke (5) | Sixth | 17 out |
| Thursday, July 13 |
| » Lost to Mariners (43-44), 5-4 | Tiger Stadium (17-25) | 31-55 | Lost 8 |
| » W: Bill Swift (6-2) L: Mike Schwabe (2-4) | Sixth | 17 out |
| » Major-league debuts: Doug Strange (Tigers) |
| Friday, July 14 |
| » Lost to Mariners (44-44), 13-0 | Tiger Stadium (17-26) | 31-56 | Lost 9 |
| » W: Brian Holman (4-4) L: Doyle Alexander (4-10) | Seventh | 18 out |
| Saturday, July 15 |
| » Lost to Mariners (45-44), 9-3 | Tiger Stadium (17-27) | 31-57 | Lost 10 |
| » W: Scott Bankhead (9-4) L: Kevin Ritz (0-1) | Seventh | 19 out |
| » Major-league debuts: Kevin Ritz (Tigers) |
| Sunday, July 16 |
| » Defeated Mariners (45-45), 8-5 | Tiger Stadium (18-27) | 32-57 | |
| » W: Charles Hudson (1-4) L: Gene Harris (2-3) S: Edwin Nunez (1) | Seventh | 19 out |
| Monday, July 17 |
| » Defeated Athletics (54-39), 2-1 | Tiger Stadium (19-27) | 33-57 | Won 2 |
| » W: Mike Henneman (6-2) L: Gene Nelson (2-4) | Seventh | 19 out |
| Tuesday, July 18 |
| » Lost to Athletics (55-39), 7-2 | Tiger Stadium (19-28) | 33-58 | |
| » W: Storm Davis (8-4) L: Dave Beard (0-1) | Seventh | 20 out |
| Thursday, July 20 |
| » Lost to Angels (55-38), 4-3 | Anaheim Stadium (0-3) | 33-59 | Lost 2 |
| » W: Chuck Finley (11-6) L: Mike Henneman (6-3) | Seventh | 19½ out |
| Friday, July 21 |
| » Lost to Angels (56-38), 8-7 | Anaheim Stadium (0-4) | 33-60 | Lost 3 |
| » W: Bryan Harvey (2-2) L: Dave Beard (0-2) | Seventh | 19½ out |
| Saturday, July 22 |
| » Lost to Angels (57-38), 5-4 | Anaheim Stadium (0-5) | 33-61 | Lost 4 |
| » W: Dan Petry (3-0) L: Charles Hudson (1-5) | Seventh | 19½ out |
| Sunday, July 23 |
| » Lost to Angels (58-38), 5-4 | Anaheim Stadium (0-6) | 33-62 | Lost 5 |
| » W: Bob McClure (3-1) L: Mike Henneman (6-4) | Seventh | 19½ out |
| Monday, July 24 |
| » Lost to Brewers (46-52), 10-0 | County Stadium (2-2) | 33-63 | Lost 6 |
| » W: Chris Bosio (11-6) L: Jack Morris (2-8) | Sixth | 20 out |
| Tuesday, July 25 |
| » Defeated Brewers (46-53), 7-2 | County Stadium (3-2) | 34-63 | |
| » W: Doyle Alexander (5-10) L: Don August (9-9) | Seventh | 19 out |
| Wednesday, July 26 |
| » Lost to Brewers (47-53), 3-2 | County Stadium (3-3) | 34-64 | |
| » W: Teddy Higuera (5-4) L: Edwin Nunez (1-2) S: Dan Plesac (24) | Sixth | 19 out |
| Thursday, July 27 |
| » Lost to Brewers (48-53), 11-1 | County Stadium (3-4) | 34-65 | Lost 2 |
| » W: Jaime Navarro (2-3) L: Paul Gibson (2-5) | Seventh | 19 out |
| Friday, July 28 |
| » Defeated Twins (49-52), 6-4 | Tiger Stadium (20-28) | 35-65 | |
| » W: Kevin Ritz (1-1) L: Frank Viola (8-12) S: Mike Henneman (3) | Seventh | 19½ out |
| » Lost to Twins (50-52), 7-3 | Tiger Stadium (20-29) | 35-66 | |
| » W: Mike Dyer (1-2) L: Jeff Robinson (1-2) | Seventh | 19½ out |
| Saturday, July 29 |
| » Defeated Twins (50-53), 3-2 | Tiger Stadium (21-29) | 36-66 | |
| » W: Mike Henneman (7-4) L: Gary Wayne (3-2) | Seventh | 18½ out |
| Sunday, July 30 |
| » Lost to Twins (51-53), 14-3 | Tiger Stadium (21-30) | 36-67 | |
| » W: Allan Anderson (11-9) L: Doyle Alexander (5-11) | Seventh | 18½ out |
| Tuesday, August 1 |
| » Lost to Rangers (57-47), 4-3 | Tiger Stadium (21-31) | 36-68 | Lost 2 |
| » W: Kevin Brown (10-6) L: Paul Gibson (2-6) S: Jeff Russell (22) | Sixth | 17½ out |
| Wednesday, August 2 |
| » Defeated Rangers (57-48), 6-4 | Tiger Stadium (22-31) | 37-68 | |
| » W: Kevin Ritz (2-1) L: Mike Jeffcoat (5-4) | Seventh | 17½ out |
| Thursday, August 3 |
| » Defeated Rangers (57-49), 9-6 | Tiger Stadium (23-31) | 38-68 | Won 2 |
| » W: Mike Henneman (8-4) L: Cecilio Guante (5-5) | Seventh | 17 out |
| Friday, August 4 |
| » Lost to White Sox (46-63), 5-4 | Comiskey Park I (3-1) | 38-69 | |
| » W: Ken Patterson (5-1) L: Paul Gibson (2-7) | Seventh | 17 out |
| Saturday, August 5 |
| » Lost to White Sox (47-63), 7-6 | Comiskey Park I (3-2) | 38-70 | Lost 2 |
| » W: Eric King (5-8) L: Doyle Alexander (5-12) S: Bobby Thigpen (24) | Seventh | 18 out |
| Sunday, August 6 |
| » Defeated White Sox (47-64), 4-3 | Comiskey Park I (4-2) | 39-70 | |
| » W: Frank Tanana (8-9) L: Greg Hibbard (2-4) | Seventh | 18 out |
| Monday, August 7 |
| » Defeated Brewers (53-58), 5-3 | Tiger Stadium (24-31) | 40-70 | Won 2 |
| » W: Kevin Ritz (3-1) L: Tony Fossas (1-2) S: Mike Henneman (4) | Seventh | 17½ out |
| » Lost to Brewers (54-58), 5-2 | Tiger Stadium (24-32) | 40-71 | |
| » W: Tom Filer (3-1) L: Paul Gibson (2-8) S: Dan Plesac (26) | Seventh | 17½ out |
| Tuesday, August 8 |
| » Defeated Brewers (54-59), 6-3 | Tiger Stadium (25-32) | 41-71 | |
| » W: Jeff Robinson (2-2) L: Don August (9-11) S: Willie Hernandez (13) | Seventh | 17½ out |
| Former Tiger Bob Harris dies in North Platte, NE at the age of 73. |
| Wednesday, August 9 |
| » Lost to Brewers (55-59), 6-1 | Tiger Stadium (25-33) | 41-72 | |
| » W: Chuck Crim (8-5) L: Jack Morris (2-9) S: Dan Plesac (27) | Seventh | 17½ out |
| Thursday, August 10 |
| » Lost to Rangers (60-53), 4-1 | Arlington Stadium (0-3) | 41-73 | Lost 2 |
| » W: Nolan Ryan (13-7) L: Doyle Alexander (5-13) S: Jeff Russell (25) | Seventh | 18 out |
| Former Tiger Tom Hughes dies in Beaumont, TX at the age of 83. |
| Friday, August 11 |
| » Lost to Rangers (61-53), 7-3 | Arlington Stadium (0-4) | 41-74 | Lost 3 |
| » W: Kevin Brown (11-6) L: Frank Tanana (8-10) | Seventh | 18½ out |
| Saturday, August 12 |
| » Defeated Rangers (61-54), 6-5 | Arlington Stadium (1-4) | 42-74 | |
| » W: Paul Gibson (3-8) L: Kenny Rogers (2-1) S: Willie Hernandez (14) | Seventh | 17½ out |
| Sunday, August 13 |
| » Defeated Rangers (61-55), 4-2 | Arlington Stadium (2-4) | 43-74 | Won 2 |
| » W: Mike Henneman (9-4) L: Kenny Rogers (2-2) S: Willie Hernandez (15) | Seventh | 17½ out |
| Monday, August 14 |
| » Lost to Orioles (61-56), 4-1 | Tiger Stadium (25-34) | 43-75 | |
| » W: Dave Schmidt (9-12) L: Jack Morris (2-10) S: Gregg Olson (18) | Seventh | 18½ out |
| Tuesday, August 15 |
| » Lost to Orioles (62-56), 2-0 | Tiger Stadium (25-35) | 43-76 | Lost 2 |
| » W: Bob Milacki (7-10) L: Doyle Alexander (5-14) | Seventh | 19½ out |
| Wednesday, August 16 |
| » Defeated Orioles (62-57), 4-0 | Tiger Stadium (26-35) | 44-76 | |
| » W: Frank Tanana (9-10) L: Pete Harnisch (2-6) | Seventh | 18½ out |
| Thursday, August 17 |
| » Lost to Yankees (56-65), 2-1 | Tiger Stadium (26-36) | 44-77 | |
| » W: Greg Cadaret (4-3) L: Brian DuBois (0-1) S: Dave Righetti (20) | Seventh | 19½ out |
| Friday, August 18 |
| » Defeated Yankees (56-66), 7-3 | Tiger Stadium (27-36) | 45-77 | |
| » W: Jeff Robinson (3-2) L: Chuck Cary (2-2) | Seventh | 18½ out |
| Saturday, August 19 |
| » Defeated Yankees (56-67), 5-4 | Tiger Stadium (28-36) | 46-77 | Won 2 |
| » W: Jack Morris (3-10) L: Dave Righetti (2-5) | Seventh | 17½ out |
| Sunday, August 20 |
| » Defeated Yankees (56-68), 7-6 | Tiger Stadium (29-36) | 47-77 | Won 3 |
| » W: Edwin Nunez (2-2) L: Eric Plunk (4-3) S: Mike Henneman (5) | Seventh | 17½ out |
| Monday, August 21 |
| » Lost to Athletics (76-49), 6-1 | Tiger Stadium (29-37) | 47-78 | |
| » W: Curt Young (4-8) L: Frank Tanana (9-11) | Seventh | 18½ out |
| Tuesday, August 22 |
| » Lost to Blue Jays (64-61), 3-2 | Skydome (1-4) | 47-79 | Lost 2 |
| » W: Mauro Gozzo (4-0) L: Edwin Nunez (2-3) | Seventh | 19½ out |
| Wednesday, August 23 |
| » Lost to Blue Jays (65-61), 11-4 | Skydome (1-5) | 47-80 | Lost 3 |
| » W: Frank Wills (1-1) L: Jeff Robinson (3-3) | Seventh | 20½ out |
| Thursday, August 24 |
| » Lost to Blue Jays (66-61), 11-3 | Skydome (1-6) | 47-81 | Lost 4 |
| » W: Mike Flanagan (7-8) L: Jack Morris (3-11) | Seventh | 21 out |
| Friday, August 25 |
| » Lost to Red Sox (61-65), 4-2 | Fenway Park (1-2) | 47-82 | Lost 5 |
| » W: Mike Smithson (7-12) L: Doyle Alexander (5-15) S: Rob Murphy (7) | Seventh | 22½ out |
| » Lost to Red Sox (62-65), 11-3 | Fenway Park (1-3) | 47-83 | Lost 6 |
| » W: Dennis Lamp (2-1) L: Kevin Ritz (3-2) | Seventh | 22½ out |
| Former Tiger Jim Brideweser dies in ElToro, CA at the age of 63. |
| Saturday, August 26 |
| » Lost to Red Sox (63-65), 5-2 | Fenway Park (1-4) | 47-84 | Lost 7 |
| » W: Roger Clemens (13-9) L: Frank Tanana (9-12) S: Lee Smith (18) | Seventh | 23½ out |
| Sunday, August 27 |
| » Lost to Red Sox (64-65), 7-1 | Fenway Park (1-5) | 47-85 | Lost 8 |
| » W: Joe Price (3-6) L: Brian DuBois (0-2) | Seventh | 24½ out |
| Monday, August 28 |
| » Lost to Red Sox (65-65), 6-3 | Fenway Park (1-6) | 47-86 | Lost 9 |
| » W: Mike Boddicker (12-9) L: Jeff Robinson (3-4) S: Lee Smith (19) | Seventh | 25 out |
| Tuesday, August 29 |
| » Lost to Royals (76-55), 12-8 | Royals Stadium (0-4) | 47-87 | Lost 10 |
| » W: Steve Crawford (3-0) L: Steve Searcy (0-1) | Seventh | 25 out |
| Wednesday, August 30 |
| » Lost to Royals (77-55), 6-1 | Royals Stadium (0-5) | 47-88 | Lost 11 |
| » W: Mark Gubicza (13-10) L: Doyle Alexander (5-16) | Seventh | 26 out |
| Thursday, August 31 |
| » Lost to Royals (78-55), 3-0 | Royals Stadium (0-6) | 47-89 | Lost 12 |
| » W: Bret Saberhagen (17-5) L: Kevin Ritz (3-3) S: Jeff Montgomery (15) | Sixth | 26 out |
| Friday, September 1 |
| » Defeated Indians (63-71), 2-1 | Tiger Stadium (30-37) | 48-89 | |
| » W: Paul Gibson (4-8) L: Doug Jones (6-8) | Seventh | 26 out |
| Saturday, September 2 |
| » Defeated Indians (63-72), 10-4 | Tiger Stadium (31-37) | 49-89 | Won 2 |
| » W: Jeff Robinson (4-4) L: Steve Davis (1-1) | Seventh | 26 out |
| Sunday, September 3 |
| » Defeated Indians (63-73), 12-3 | Tiger Stadium (32-37) | 50-89 | Won 3 |
| » W: Jack Morris (4-11) L: Tom Candiotti (12-7) | Seventh | 25 out |
| Former Tiger Rip Sewell dies in Plant City, FL at the age of 83. |
| Monday, September 4 |
| » Defeated Royals (80-57), 5-1 | Tiger Stadium (33-37) | 51-89 | Won 4 |
| » W: Doyle Alexander (6-16) L: Bret Saberhagen (17-6) S: Mike Henneman (6) | Seventh | 25 out |
| Tuesday, September 5 |
| » Defeated Royals (80-58), 10-2 | Tiger Stadium (34-37) | 52-89 | Won 5 |
| » W: Kevin Ritz (4-3) L: Tom Gordon (16-6) | Seventh | 25 out |
| Wednesday, September 6 |
| » Defeated Royals (80-59), 11-5 | Tiger Stadium (35-37) | 53-89 | Won 6 |
| » W: Edwin Nunez (3-3) L: Charlie Leibrandt (5-11) S: Brian DuBois (1) | Seventh | 25 out |
| Thursday, September 7 |
| » Major-league debuts: John Barfield (Rangers) |
| Friday, September 8 |
| » Defeated White Sox (58-82), 7-5 | Tiger Stadium (36-37) | 54-89 | Won 7 |
| » W: Jack Morris (5-11) L: Greg Hibbard (4-7) S: Mike Henneman (7) | Seventh | 24½ out |
| Saturday, September 9 |
| » Lost to White Sox (59-82), 13-3 | Tiger Stadium (36-38) | 54-90 | |
| » W: Melido Perez (9-13) L: Jeff Robinson (4-5) | Seventh | 25½ out |
| Sunday, September 10 |
| » Defeated White Sox (59-83), 6-5 | Tiger Stadium (37-38) | 55-90 | |
| » W: Mike Henneman (10-4) L: Bobby Thigpen (2-6) | Seventh | 25½ out |
| Tuesday, September 12 |
| » Lost to Indians (66-78), 1-0 | Cleveland Stadium (1-3) | 55-91 | |
| » W: Bud Black (11-11) L: Frank Tanana (9-13) | Seventh | 25½ out |
| Wednesday, September 13 |
| » Defeated Indians (66-79), 3-1 | Cleveland Stadium (2-3) |
