| Friday, February 24 |
| Former Red Sparky Adams dies in Pottsville, PA at the age of 95. |
| Monday, April 3 |
| » Defeated Dodgers (0-1), 6-4 | Riverfront Stadium (1-0) | 1-0 | |
| » W: Danny Jackson (1-0) L: Tim Belcher (0-1) S: John Franco (1) | First | -- |
| Wednesday, April 5 |
| » Defeated Dodgers (0-2), 4-3 | Riverfront Stadium (2-0) | 2-0 | Won 2 |
| » W: Tom Browning (1-0) L: Orel Hershiser (0-1) S: John Franco (2) | First | -- |
| Thursday, April 6 |
| » Lost to Dodgers (1-2), 4-1 | Riverfront Stadium (2-1) | 2-1 | |
| » W: Tim Leary (1-0) L: Rick Mahler (0-1) | First | -- |
| Friday, April 7 |
| » Defeated Giants (2-2), 4-3 | Riverfront Stadium (3-1) | 3-1 | |
| » W: Tim Birtsas (1-0) L: Joe Price (0-1) | First | -- |
| Sunday, April 9 |
| » Lost to Giants (3-2), 9-1 | Riverfront Stadium (3-2) | 3-2 | |
| » W: Rick Reuschel (2-0) L: Danny Jackson (1-1) | First | -- |
| Monday, April 10 |
| » Defeated Astros (2-5), 8-3 | Astrodome (1-0) | 4-2 | |
| » W: Tom Browning (2-0) L: Bob Knepper (0-2) S: Rob Dibble (1) | First | -- |
| Tuesday, April 11 |
| » Lost to Astros (3-5), 5-3 | Astrodome (1-1) | 4-3 | |
| » W: Jim Deshaies (1-1) L: Rick Mahler (0-2) S: Dave Smith (1) | Second | ½ out |
| Wednesday, April 12 |
| » Defeated Astros (3-6), 3-1 | Astrodome (2-1) | 5-3 | |
| » W: Rob Dibble (1-0) L: Dave Smith (0-1) S: John Franco (3) | First | -- |
| Friday, April 14 |
| » Lost to Padres (6-5), 6-5 | San Diego/Jack Murphy Stadium (0-1) | 5-4 | |
| » W: Eric Show (2-1) L: Danny Jackson (1-2) S: Mark Davis (5) | Second | 1 out |
| Saturday, April 15 |
| » Defeated Padres (6-6), 6-3 | San Diego/Jack Murphy Stadium (1-1) | 6-4 | |
| » W: Norm Charlton (1-0) L: Greg Booker (0-1) S: John Franco (4) | Second | 1 out |
| Sunday, April 16 |
| » Defeated Padres (6-7), 5-0 | San Diego/Jack Murphy Stadium (2-1) | 7-4 | Won 2 |
| » W: Rick Mahler (1-2) L: Ed Whitson (2-1) | Second | ½ out |
| Monday, April 17 |
| » Defeated Dodgers (5-8), 3-2 | Dodger Stadium (1-0) | 8-4 | Won 3 |
| » W: Rob Dibble (2-0) L: Jay Howell (0-1) S: John Franco (5) | Second | ½ out |
| Tuesday, April 18 |
| » Lost to Dodgers (6-8), 6-0 | Dodger Stadium (1-1) | 8-5 | |
| » W: Tim Belcher (1-1) L: Danny Jackson (1-3) | Second | ½ out |
| Wednesday, April 19 |
| » Lost to Dodgers (7-8), 3-0 | Dodger Stadium (1-2) | 8-6 | Lost 2 |
| » W: Mike Morgan (1-1) L: Tom Browning (2-1) S: Jay Howell (1) | Second | ½ out |
| Friday, April 21 |
| » Lost to Astros (7-10), 7-0 | Riverfront Stadium (3-3) | 8-7 | Lost 3 |
| » W: Jim Deshaies (2-2) L: Rick Mahler (1-3) | Second | ½ out |
| Saturday, April 22 |
| » Defeated Astros (7-11), 5-4 | Riverfront Stadium (4-3) | 9-7 | |
| » W: Tim Birtsas (2-0) L: Danny Darwin (1-1) | Second | ½ out |
| Sunday, April 23 |
| » Lost to Astros (8-11), 5-2 | Riverfront Stadium (4-4) | 9-8 | |
| » W: Bob Knepper (1-3) L: Danny Jackson (1-4) S: Larry Andersen (1) | Second | ½ out |
| Tuesday, April 25 |
| » Defeated Expos (10-10), 6-1 | Riverfront Stadium (5-4) | 10-8 | |
| » W: Tom Browning (3-1) L: Dennis Martinez (1-1) | Second | ½ out |
| Wednesday, April 26 |
| » Defeated Expos (10-11), 6-5 | Riverfront Stadium (6-4) | 11-8 | Won 2 |
| » W: Rick Mahler (2-3) L: Pascual Perez (0-2) S: John Franco (6) | First | -- |
| Friday, April 28 |
| » Defeated Phillies (10-11), 3-0 | Veteran's Stadium (1-0) | 12-8 | Won 3 |
| » W: Jose Rijo (1-0) L: Don Carman (1-3) S: John Franco (7) | First | -- |
| Saturday, April 29 |
| » Lost to Phillies (11-11), 8-0 | Veteran's Stadium (1-1) | 12-9 | |
| » W: Mike Maddux (1-0) L: Danny Jackson (1-5) | First | -- |
| Sunday, April 30 |
| » Defeated Phillies (11-12), 5-3 | Veteran's Stadium (2-1) | 13-9 | |
| » W: Rob Dibble (3-0) L: Larry McWilliams (1-1) S: John Franco (8) | First | -- |
| Monday, May 1 |
| » Defeated Expos (13-12), 19-6 | Stade Olympique (1-0) | 14-9 | Won 2 |
| » W: Rick Mahler (3-3) L: Pascual Perez (0-3) | First | -- |
| Tuesday, May 2 |
| » Lost to Expos (14-12), 6-4 | Stade Olympique (1-1) | 14-10 | |
| » W: Tim Burke (2-1) L: Kent Tekulve (0-1) | First | -- |
| Former Red Virgil Stallcup dies in Greenville, SC at the age of 68. |
| Wednesday, May 3 |
| » Defeated Mets (14-11), 6-4 | Shea Stadium (1-0) | 15-10 | |
| » W: Jose Rijo (2-0) L: Sid Fernandez (3-1) S: John Franco (9) | First | -- |
| Thursday, May 4 |
| » Lost to Mets (15-11), 3-2 | Shea Stadium (1-1) | 15-11 | |
| » W: Randy Myers (2-1) L: Rob Dibble (3-1) | First | -- |
| Friday, May 5 |
| » Lost to Phillies (12-15), 7-0 | Riverfront Stadium (6-5) | 15-12 | Lost 2 |
| » W: Ken Howell (3-1) L: Tom Browning (3-2) | First | -- |
| Saturday, May 6 |
| » Defeated Phillies (12-16), 7-4 | Riverfront Stadium (7-5) | 16-12 | |
| » W: Rick Mahler (4-3) L: Larry McWilliams (1-2) S: John Franco (10) | First | -- |
| Sunday, May 7 |
| » Lost to Phillies (13-16), 5-0 | Riverfront Stadium (7-6) | 16-13 | |
| » W: Alex Madrid (1-0) L: Jack Armstrong (0-1) | First | -- |
| Former Red Howie Moss dies in Baltimore, MD at the age of 70. |
| Monday, May 8 |
| » Defeated Mets (16-13), 3-0 | Riverfront Stadium (8-6) | 17-13 | |
| » W: Jose Rijo (3-0) L: Bob Ojeda (1-4) S: John Franco (11) | First | -- |
| Tuesday, May 9 |
| » Lost to Mets (17-13), 3-1 | Riverfront Stadium (8-7) | 17-14 | |
| » W: Sid Fernandez (4-1) L: Danny Jackson (1-6) S: Randy Myers (6) | First | -- |
| Wednesday, May 10 |
| » Lost to Mets (18-13), 11-4 | Riverfront Stadium (8-8) | 17-15 | Lost 2 |
| » W: Ron Darling (2-3) L: Tom Browning (3-3) S: Rick Aguilera (1) | Second | ½ out |
| Friday, May 12 |
| » Defeated Cardinals (19-14), 5-0 | Busch Stadium II (1-0) | 18-15 | |
| » W: Rick Mahler (5-3) L: Ted Power (0-1) | Second | ½ out |
| Saturday, May 13 |
| » Defeated Cardinals (19-15), 3-2 | Busch Stadium II (2-0) | 19-15 | Won 2 |
| » W: Jose Rijo (4-0) L: Cris Carpenter (1-2) S: John Franco (12) | First | -- |
| Sunday, May 14 |
| » Defeated Cardinals (19-16), 5-2 | Busch Stadium II (3-0) | 20-15 | Won 3 |
| » W: Danny Jackson (2-6) L: Ken Hill (2-2) S: John Franco (13) | First | -- |
| Monday, May 15 |
| » Defeated Pirates (14-21), 6-5 | Riverfront Stadium (9-8) | 21-15 | Won 4 |
| » W: Norm Charlton (2-0) L: Jeff Robinson (2-4) | First | -- |
| Tuesday, May 16 |
| » Lost to Pirates (15-21), 5-0 | Riverfront Stadium (9-9) | 21-16 | |
| » W: Randy Kramer (1-1) L: Rick Mahler (5-4) | First | -- |
| Wednesday, May 17 |
| » Defeated Pirates (15-22), 5-4 | Riverfront Stadium (10-9) | 22-16 | |
| » W: John Franco (1-0) L: Bill Landrum (0-1) | First | -- |
| Friday, May 19 |
| » Lost to Cubs (21-18), 8-2 | Riverfront Stadium (10-10) | 22-17 | |
| » W: Greg Maddux (2-5) L: Danny Jackson (2-7) | First | -- |
| Saturday, May 20 |
| » Lost to Cubs (22-18), 7-3 | Riverfront Stadium (10-11) | 22-18 | Lost 2 |
| » W: Paul Kilgus (4-4) L: Tom Browning (3-4) S: Pat Perry (1) | First | -- |
| Sunday, May 21 |
| » Defeated Cubs (22-19), 7-2 | Riverfront Stadium (11-11) | 23-18 | |
| » W: Rick Mahler (6-4) L: Mike Bielecki (3-2) | First | -- |
| Tuesday, May 23 |
| » Defeated Cardinals (22-20), 6-4 | Riverfront Stadium (12-11) | 24-18 | Won 2 |
| » W: Danny Jackson (3-7) L: Matt Kinzer (0-1) S: John Franco (14) | First | -- |
| Wednesday, May 24 |
| » Defeated Cardinals (22-21), 5-1 | Riverfront Stadium (13-11) | 25-18 | Won 3 |
| » W: Tom Browning (4-4) L: Ken Hill (2-3) | First | -- |
| Friday, May 26 |
| » Defeated Cubs (25-20), 10-8 | Wrigley Field (1-0) | 26-18 | Won 4 |
| » W: Rob Dibble (4-1) L: Calvin Schiraldi (1-2) | First | -- |
| Saturday, May 27 |
| » Lost to Cubs (26-20), 5-3 | Wrigley Field (1-1) | 26-19 | |
| » W: Rick Sutcliffe (6-3) L: Jose Rijo (4-1) | First | -- |
| Sunday, May 28 |
| » Lost to Cubs (27-20), 6-1 | Wrigley Field (1-2) | 26-20 | Lost 2 |
| » W: Mike Bielecki (4-2) L: Danny Jackson (3-8) | First | -- |
| Monday, May 29 |
| » Lost to Pirates (20-27), 12-3 | Three Rivers Stadium (0-1) | 26-21 | Lost 3 |
| » W: Bob Walk (5-3) L: Tom Browning (4-5) S: Bob Kipper (1) | Second | 1 out |
| Tuesday, May 30 |
| » Lost to Pirates (21-27), 2-0 | Three Rivers Stadium (0-2) | 26-22 | Lost 4 |
| » W: Doug Drabek (3-5) L: Rick Mahler (6-5) S: Randy Kramer (1) | Second | 2 out |
| Wednesday, May 31 |
| » Defeated Pirates (21-28), 4-3 | Three Rivers Stadium (1-2) | 27-22 | |
| » W: Jose Rijo (5-1) L: Neal Heaton (1-6) S: John Franco (15) | Second | 1 out |
| Friday, June 2 |
| » Defeated Padres (29-26), 9-4 | Riverfront Stadium (14-11) | 28-22 | Won 2 |
| » W: Tom Browning (5-5) L: Walt Terrell (4-6) | Second | 1 out |
| Saturday, June 3 |
| » Defeated Padres (29-27), 6-2 | Riverfront Stadium (15-11) | 29-22 | Won 3 |
| » W: Rick Mahler (7-5) L: Eric Show (6-6) | Second | 1 out |
| Sunday, June 4 |
| » Defeated Padres (29-28), 5-3 | Riverfront Stadium (16-11) | 30-22 | Won 4 |
| » W: Danny Jackson (4-8) L: Bruce Hurst (5-4) S: John Franco (16) | First | -- |
| Monday, June 5 |
| » Lost to Giants (32-23), 11-8 | Riverfront Stadium (16-12) | 30-23 | |
| » W: Scott Garrelts (4-1) L: Jose Rijo (5-2) | Second | 1 out |
| Tuesday, June 6 |
| » Defeated Giants (32-24), 4-3 | Riverfront Stadium (17-12) | 31-23 | |
| » W: John Franco (2-0) L: Mike LaCoss (2-4) | Second | 1 out |
| » Lost to Giants (33-24), 3-2 | Riverfront Stadium (17-13) | 31-24 | |
| » W: Rick Reuschel (11-2) L: Rob Dibble (4-2) S: Craig Lefferts (10) | Second | 1 out |
| » Major-league debuts: Scott Scudder (Reds) |
| Wednesday, June 7 |
| » Defeated Giants (33-25), 12-5 | Riverfront Stadium (18-13) | 32-24 | |
| » W: Rick Mahler (8-5) L: Atlee Hammaker (5-4) | First | -- |
| Thursday, June 8 |
| » Defeated Giants (33-26), 3-2 | Riverfront Stadium (19-13) | 33-24 | Won 2 |
| » W: Rob Dibble (5-2) L: Mike LaCoss (2-5) S: John Franco (17) | First | -- |
| Friday, June 9 |
| » Defeated Dodgers (28-30), 4-0 | Dodger Stadium (2-2) | 34-24 | Won 3 |
| » W: Jose Rijo (6-2) L: Orel Hershiser (7-5) | First | -- |
| Saturday, June 10 |
| » Defeated Dodgers (28-31), 5-0 | Dodger Stadium (3-2) | 35-24 | Won 4 |
| » W: Tom Browning (6-5) L: Tim Belcher (4-5) | First | -- |
| Former Red Joe Stripp dies in Orlando, FL at the age of 87. |
| Sunday, June 11 |
| » Lost to Dodgers (29-31), 3-1 | Dodger Stadium (3-3) | 35-25 | |
| » W: Tim Leary (5-4) L: Scott Scudder (0-1) S: Jay Howell (12) | Second | 1 out |
| Monday, June 12 |
| » Lost to Dodgers (30-31), 9-2 | Dodger Stadium (3-4) | 35-26 | Lost 2 |
| » W: Mike Morgan (5-4) L: Rick Mahler (8-6) S: John Wetteland (1) | Third | 1½ out |
| Tuesday, June 13 |
| » Defeated Padres (30-35), 9-6 | San Diego/Jack Murphy Stadium (3-1) | 36-26 | |
| » W: Danny Jackson (5-8) L: Walt Terrell (4-8) | Second | ½ out |
| Wednesday, June 14 |
| » Lost to Padres (31-35), 4-2 | San Diego/Jack Murphy Stadium (3-2) | 36-27 | |
| » W: Eric Show (7-6) L: Jose Rijo (6-3) S: Mark Davis (18) | Third | 1½ out |
| Thursday, June 15 |
| » Lost to Padres (32-35), 1-0 | San Diego/Jack Murphy Stadium (3-3) | 36-28 | Lost 2 |
| » W: Greg Harris (2-2) L: Tim Birtsas (2-1) | Third | 1½ out |
| Friday, June 16 |
| » Defeated Giants (38-28), 5-4 | Candlestick Park (1-0) | 37-28 | |
| » W: Norm Charlton (3-0) L: Rich Gossage (1-1) S: John Franco (18) | Second | ½ out |
| Saturday, June 17 |
| » Lost to Giants (39-28), 8-1 | Candlestick Park (1-1) | 37-29 | |
| » W: Dennis Cook (1-0) L: Danny Jackson (5-9) | Third | 1½ out |
| Sunday, June 18 |
| » Lost to Giants (40-28), 2-1 | Candlestick Park (1-2) | 37-30 | Lost 2 |
| » W: Mike LaCoss (3-5) L: Jose Rijo (6-4) S: Craig Lefferts (13) | Third | 2½ out |
| Wednesday, June 21 |
| » Lost to Braves (28-40), 4-3 | Atlanta-Fulton County Stadium (0-1) | 37-31 | Lost 3 |
| » W: Mark Eichhorn (1-1) L: John Franco (2-1) | Third | 5 out |
| » Lost to Braves (29-40), 1-0 | Atlanta-Fulton County Stadium (0-2) | 37-32 | Lost 4 |
| » W: John Smoltz (9-5) L: Rick Mahler (8-7) S: Joe Boever (11) | Third | 5 out |
| Thursday, June 22 |
| » Defeated Braves (29-41), 6-1 | Atlanta-Fulton County Stadium (1-2) | 38-32 | |
| » W: Scott Scudder (1-1) L: Tom Glavine (7-4) | Third | 4½ out |
| Friday, June 23 |
| » Defeated Dodgers (35-36), 3-1 | Riverfront Stadium (20-13) | 39-32 | Won 2 |
| » W: Jose Rijo (7-4) L: Mike Morgan (5-6) S: John Franco (19) | Third | 4½ out |
| Saturday, June 24 |
| » Lost to Dodgers (36-36), 10-3 | Riverfront Stadium (20-14) | 39-33 | |
| » W: Fernando Valenzuela (4-5) L: Tim Birtsas (2-2) S: Tim Belcher (1) | Third | 5½ out |
| Sunday, June 25 |
| » Lost to Dodgers (37-36), 7-0 | Riverfront Stadium (20-15) | 39-34 | Lost 2 |
| » W: Orel Hershiser (9-6) L: Tom Browning (6-6) | Third | 5½ out |
| Monday, June 26 |
| » Defeated Dodgers (37-37), 5-3 | Riverfront Stadium (21-15) | 40-34 | |
| » W: Rob Dibble (6-2) L: Tim Belcher (4-7) S: John Franco (20) | Third | 5½ out |
| Tuesday, June 27 |
| » Defeated Braves (29-45), 9-3 | Riverfront Stadium (22-15) | 41-34 | Won 2 |
| » W: Scott Scudder (2-1) L: John Smoltz (9-6) | Third | 4½ out |
| Wednesday, June 28 |
| » Lost to Braves (30-45), 4-3 | Riverfront Stadium (22-16) | 41-35 | |
| » W: Tom Glavine (8-4) L: Jose Rijo (7-5) S: Joe Boever (12) | Third | 4½ out |
| Thursday, June 29 |
| » Lost to Braves (31-45), 2-1 | Riverfront Stadium (22-17) | 41-36 | Lost 2 |
| » W: Marty Clary (1-0) L: Rob Dibble (6-3) | Third | 5½ out |
| Friday, June 30 |
| » Lost to Mets (40-35), 11-1 | Riverfront Stadium (22-18) | 41-37 | Lost 3 |
| » W: Ron Darling (6-5) L: Rick Mahler (8-8) | Third | 5½ out |
| Saturday, July 1 |
| » Defeated Mets (40-36), 6-2 | Riverfront Stadium (23-18) | 42-37 | |
| » W: Jack Armstrong (1-1) L: Dwight Gooden (9-4) S: John Franco (21) | Third | 4½ out |
| Sunday, July 2 |
| » Lost to Mets (41-36), 7-2 | Riverfront Stadium (23-19) | 42-38 | |
| » W: Sid Fernandez (6-2) L: Scott Scudder (2-2) | Third | 5½ out |
| Monday, July 3 |
| » Lost to Phillies (29-49), 2-1 | Veteran's Stadium (2-2) | 42-39 | Lost 2 |
| » W: Ken Howell (7-5) L: Jose Rijo (7-6) S: Roger McDowell (8) | Third | 6 out |
| Tuesday, July 4 |
| » Defeated Phillies (29-50), 2-1 | Veteran's Stadium (3-2) | 43-39 | |
| » W: Tom Browning (7-6) L: Terry Mulholland (1-3) S: John Franco (22) | Third | 5 out |
| Wednesday, July 5 |
| » Lost to Phillies (30-50), 3-2 | Veteran's Stadium (3-3) | 43-40 | |
| » W: Roger McDowell (2-5) L: John Franco (2-2) | Third | 6 out |
| Thursday, July 6 |
| » Defeated Mets (42-39), 10-2 | Shea Stadium (2-1) | 44-40 | |
| » W: Danny Jackson (6-9) L: David West (0-1) S: Kent Tekulve (1) | Third | 6 out |
| Friday, July 7 |
| » Lost to Mets (43-39), 7-1 | Shea Stadium (2-2) | 44-41 | |
| » W: Sid Fernandez (7-2) L: Scott Scudder (2-3) | Third | 6 out |
| Saturday, July 8 |
| » Lost to Mets (44-39), 8-3 | Shea Stadium (2-3) | 44-42 | Lost 2 |
| » W: David Cone (6-5) L: Tom Browning (7-7) | Third | 7 out |
| Sunday, July 9 |
| » Lost to Mets (45-39), 6-3 | Shea Stadium (2-4) | 44-43 | Lost 3 |
| » W: Rick Aguilera (4-3) L: Norm Charlton (3-1) | Third | 7 out |
| Thursday, July 13 |
| » Lost to Expos (50-38), 6-3 | Riverfront Stadium (23-20) | 44-44 | Lost 4 |
| » W: Dennis Martinez (10-1) L: Kent Tekulve (0-2) S: Tim Burke (18) | Third | 8 out |
| Friday, July 14 |
| » Lost to Expos (51-38), 1-0 | Riverfront Stadium (23-21) | 44-45 | Lost 5 |
| » W: Bryn Smith (9-3) L: Tom Browning (7-8) S: Joe Hesketh (3) | Third | 8 out |
| Saturday, July 15 |
| » Defeated Expos (51-39), 5-3 | Riverfront Stadium (24-21) | 45-45 | |
| » W: Rick Mahler (9-8) L: Mark Langston (10-8) S: John Franco (23) | Third | 8 out |
| » Major-league debuts: Joe Oliver (Reds) |
| Sunday, July 16 |
| » Lost to Expos (52-39), 6-3 | Riverfront Stadium (24-22) | 45-46 | |
| » W: Steve Frey (3-0) L: Kent Tekulve (0-3) S: Tim Burke (19) | Third | 9 out |
| Monday, July 17 |
| » Lost to Phillies (35-54), 4-1 | Riverfront Stadium (24-23) | 45-47 | Lost 2 |
| » W: Ken Howell (8-5) L: Ron Robinson (0-1) S: Roger McDowell (9) | Third | 10 out |
| Tuesday, July 18 |
| » Lost to Phillies (36-54), 6-5 | Riverfront Stadium (24-24) | 45-48 | Lost 3 |
| » W: Todd Frohwirth (1-0) L: Danny Jackson (6-10) S: Roger McDowell (10) | Fourth | 11 out |
| Wednesday, July 19 |
| » Lost to Phillies (37-54), 9-4 | Riverfront Stadium (24-25) | 45-49 | Lost 4 |
| » W: Dennis Cook (4-3) L: Tom Browning (7-9) | Fourth | 12 out |
| Thursday, July 20 |
| » Lost to Expos (54-41), 4-1 | Stade Olympique (1-2) | 45-50 | Lost 5 |
| » W: Mark Langston (11-8) L: Rick Mahler (9-9) | Fourth | 12 out |
| Friday, July 21 |
| » Lost to Expos (55-41), 3-1 | Stade Olympique (1-3) | 45-51 | Lost 6 |
| » W: Kevin Gross (8-8) L: Tim Leary (6-8) S: Tim Burke (21) | Fourth | 13 out |
| Saturday, July 22 |
| » Lost to Expos (56-41), 6-5 | Stade Olympique (1-4) | 45-52 | Lost 7 |
| » W: Andy McGaffigan (2-4) L: John Franco (2-3) | Fourth | 13 out |
| Sunday, July 23 |
| » Lost to Expos (57-41), 12-4 | Stade Olympique (1-5) | 45-53 | Lost 8 |
| » W: Dennis Martinez (11-1) L: Danny Jackson (6-11) | Fifth | 13 out |
| Tuesday, July 25 |
| » Lost to Padres (48-52), 6-2 | Riverfront Stadium (24-26) | 45-54 | Lost 9 |
| » W: Ed Whitson (14-6) L: Tom Browning (7-10) | Fifth | 14½ out |
| Wednesday, July 26 |
| » Lost to Padres (49-52), 5-3 | Riverfront Stadium (24-27) | 45-55 | Lost 10 |
| » W: Mark Grant (4-1) L: John Franco (2-4) S: Mark Davis (25) | Fifth | 14½ out |
| Thursday, July 27 |
| » Defeated Padres (49-53), 6-1 | Riverfront Stadium (25-27) | 46-55 | |
| » W: Tim Leary (7-8) L: Greg Harris (3-6) | Fifth | 13½ out |
| Friday, July 28 |
| » Defeated Braves (42-61), 4-2 | Atlanta-Fulton County Stadium (2-2) | 47-55 | Won 2 |
| » W: Norm Charlton (4-1) L: Sergio Valdez (0-2) S: Bob Sebra (1) | Fifth | 13½ out |
| Saturday, July 29 |
| » Defeated Braves (42-62), 4-1 | Atlanta-Fulton County Stadium (3-2) | 48-55 | Won 3 |
| » W: Tom Browning (8-10) L: John Smoltz (11-8) S: John Franco (24) | Fourth | 12½ out |
| Sunday, July 30 |
| » Lost to Braves (43-62), 5-2 | Atlanta-Fulton County Stadium (3-3) | 48-56 | |
| » W: Derek Lilliquist (6-6) L: Rick Mahler (9-10) S: Joe Boever (18) | Fourth | 12½ out |
| Tuesday, August 1 |
| » Lost to Astros (61-45), 5-0 | Riverfront Stadium (25-28) | 48-57 | Lost 2 |
| » W: Rick Rhoden (1-3) L: Tim Leary (7-9) | Fifth | 13½ out |
| Wednesday, August 2 |
| » Defeated Astros (61-46), 5-2 | Riverfront Stadium (26-28) | 49-57 | |
| » W: Ron Robinson (1-1) L: Jim Deshaies (10-5) S: John Franco (25) | Fifth | 12½ out |
| Thursday, August 3 |
| » Defeated Astros (61-47), 18-2 | Riverfront Stadium (27-28) | 50-57 | Won 2 |
| » W: Tom Browning (9-10) L: Jim Clancy (5-9) | Fifth | 11½ out |
| Friday, August 4 |
| » Defeated Braves (43-66), 5-4 | Riverfront Stadium (28-28) | 51-57 | Won 3 |
| » W: John Franco (3-4) L: Joe Boever (4-4) | Fifth | 11½ out |
| Saturday, August 5 |
| » Lost to Braves (44-66), 7-1 | Riverfront Stadium (28-29) | 51-58 | |
| » W: Derek Lilliquist (7-6) L: Scott Scudder (2-4) | Fourth | 12½ out |
| Sunday, August 6 |
| » Defeated Braves (44-67), 3-2 | Riverfront Stadium (29-29) | 52-58 | |
| » W: Norm Charlton (5-1) L: Joe Boever (4-5) | Fourth | 11½ out |
| Monday, August 7 |
| » Defeated Giants (64-48), 10-2 | Candlestick Park (2-2) | 53-58 | Won 2 |
| » W: Ron Robinson (2-1) L: Jeff Brantley (6-1) S: Tim Birtsas (1) | Fourth | 10½ out |
| Tuesday, August 8 |
| » Defeated Giants (64-49), 10-4 | Candlestick Park (3-2) | 54-58 | Won 3 |
| » W: Tom Browning (10-10) L: Russ Swan (0-2) | Fourth | 9½ out |
| Wednesday, August 9 |
| » Lost to Giants (65-49), 10-1 | Candlestick Park (3-3) | 54-59 | |
| » W: Don Robinson (11-7) L: Rick Mahler (9-11) | Fourth | 10½ out |
| Thursday, August 10 |
| » Lost to Giants (66-49), 4-3 | Candlestick Park (3-4) | 54-60 | Lost 2 |
| » W: Dave Dravecky (1-0) L: Scott Scudder (2-5) S: Steve Bedrosian (15) | Fourth | 11½ out |
| Friday, August 11 |
| » Defeated Astros (63-53), 6-1 | Astrodome (3-1) | 55-60 | |
| » W: Tim Leary (8-9) L: Rick Rhoden (1-4) S: Rob Dibble (2) | Fourth | 11½ out |
| Saturday, August 12 |
| » Lost to Astros (64-53), 6-5 | Astrodome (3-2) | 55-61 | |
| » W: Dave Smith (2-3) L: John Franco (3-5) | Fourth | 11½ out |
| Sunday, August 13 |
| » Defeated Astros (64-54), 5-0 | Astrodome (4-2) | 56-61 | |
| » W: Tom Browning (11-10) L: Jim Clancy (6-10) | Fourth | 10½ out |
| Tuesday, August 15 |
| » Lost to Cubs (69-50), 5-2 | Riverfront Stadium (29-30) | 56-62 | |
| » W: Mitch Williams (2-2) L: Mike Roesler (0-1) | Fourth | 11½ out |
| Wednesday, August 16 |
| » Lost to Cubs (70-50), 5-1 | Riverfront Stadium (29-31) | 56-63 | Lost 2 |
| » W: Mike Bielecki (14-5) L: Tim Leary (8-10) | Fourth | 11½ out |
| Thursday, August 17 |
| » Lost to Cubs (71-50), 3-2 | Riverfront Stadium (29-32) | 56-64 | Lost 3 |
| » W: Rick Sutcliffe (13-9) L: John Franco (3-6) S: Mitch Williams (31) | Fifth | 12½ out |
| Friday, August 18 |
| » Defeated Cardinals (64-56), 6-2 | Riverfront Stadium (30-32) | 57-64 | |
| » W: Tom Browning (12-10) L: Ken Hill (6-10) | Fourth | 12 out |
| » Defeated Cardinals (64-57), 8-3 | Riverfront Stadium (31-32) | 58-64 | Won 2 |
| » W: Rob Dibble (7-3) L: Todd Worrell (2-4) | Fourth | 12 out |
| » Major-league debuts: Todd Zeile (Cardinals) |
| Saturday, August 19 |
| » Lost to Cardinals (65-57), 5-1 | Riverfront Stadium (31-33) | 58-65 | |
| » W: Joe Magrane (16-7) L: Rick Mahler (9-12) | Fourth | 12 out |
| Sunday, August 20 |
| » Lost to Cardinals (66-57), 8-1 | Riverfront Stadium (31-34) | 58-66 | Lost 2 |
| » W: Jose DeLeon (13-11) L: Tim Leary (8-11) | Fourth | 13 out |
| Monday, August 21 |
| » Defeated Cubs (71-54), 6-5 | Wrigley Field (2-2) | 59-66 | |
| » W: Norm Charlton (6-1) L: Calvin Schiraldi (3-6) S: John Franco (26) | Fourth | 12 out |
| Tuesday, August 22 |
| » Defeated Cubs (71-55), 7-2 | Wrigley Field (3-2) | 60-66 | Won 2 |
| » Manager: Tommy Helms |
| » W: Tom Browning (13-10) L: Joe Kraemer (0-1) | Fourth | 12 out |
| Wednesday, August 23 |
| » Defeated Cubs (71-56), 8-5 | Wrigley Field (4-2) | 61-66 | Won 3 |
| » W: Scott Scudder (3-5) L: Greg Maddux (14-10) | Fourth | 12 out |
| Friday, August 25 |
| » Lost to Pirates (56-71), 12-3 | Riverfront Stadium (31-35) | 61-67 | |
| » W: Jeff Robinson (6-11) L: Rick Mahler (9-13) | Fourth | 12 out |
| Saturday, August 26 |
| » Defeated Pirates (56-72), 6-4 | Riverfront Stadium (32-35) | 62-67 | |
| » W: Ron Robinson (3-1) L: Rick Reed (1-4) S: John Franco (27) | Fourth | 12 out |
| Sunday, August 27 |
| » Defeated Pirates (56-73), 1-0 | Riverfront Stadium (33-35) | 63-67 | Won 2 |
| » W: Tom Browning (14-10) L: Randy Kramer (4-7) S: John Franco (28) | Fourth | 11 out |
| Monday, August 28 |
| » Lost to Cardinals (71-59), 3-2 | Busch Stadium II (3-1) | 63-68 | |
| » W: John Costello (3-2) L: Rob Dibble (7-4) S: Todd Worrell (20) | Fourth | 11 out |
| Tuesday, August 29 |
| » Lost to Cardinals (72-59), 4-2 | Busch Stadium II (3-2) | 63-69 | Lost 2 |
| » W: Joe Magrane (18-7) L: Tim Leary (8-12) | Fourth | 11 out |
| Wednesday, August 30 |
| » Defeated Cardinals (72-60), 2-0 | Busch Stadium II (4-2) | 64-69 | |
| » W: Rob Dibble (8-4) L: Todd Worrell (2-5) S: John Franco (29) | Fourth | 11 out |
| Friday, September 1 |
| » Defeated Pirates (58-75), 11-5 | Three Rivers Stadium (2-2) | 65-69 | Won 2 |
| » W: Ron Robinson (4-1) L: Bob Patterson (0-1) | Fourth | 11 out |
| » Major-league debuts: Rosario Rodriguez (Reds) |
| Saturday, September 2 |
| » Defeated Pirates (58-76), 6-2 | Three Rivers Stadium (3-2) | 66-69 | Won 3 |
| » W: Tom Browning (15-10) L: Bob Walk (11-10) | Fourth | 11 out |
| Sunday, September 3 |
| » Lost to Pirates (59-76), 3-1 | Three Rivers Stadium (3-3) | 66-70 | |
| » W: Doug Drabek (12-10) L: Scott Scudder (3-6) S: Bill Landrum (21) | Fourth | 12 out |
| Monday, September 4 |
| » Lost to Giants (79-58), 9-8 | Riverfront Stadium (33-36) | 66-71 | Lost 2 |
| » W: Ernie Camacho (1-0) L: John Franco (3-7) S: Steve Bedrosian (19) | Third | 13 out |
| Tuesday, September 5 |
| » Defeated Giants (79-59), 6-5 | Riverfront Stadium (34-36) | 67-71 | |
| » W: Jack Armstrong (2-1) L: Mike LaCoss (7-10) S: John Franco (30) | Third | 12 out |
| Wednesday, September 6 |
| » Defeated Dodgers (65-74), 9-5 | Riverfront Stadium (35-36) | 68-71 | Won 2 |
| » W: Rosario Rodriguez (1-0) L: Ray Searage (3-4) | Fourth | 12 out |
| » Major-league debuts: Mike Munoz (Dodgers) |
| Thursday, September 7 |
| » Lost to Dodgers (66-74), 8-2 | Riverfront Stadium (35-37) | 68-72 | |
| » W: Fernando Valenzuela (10-12) L: Tom Browning (15-11) | Third | 13 out |
| Friday, September 8 |
| » Defeated Braves (55-86), 5-1 | Riverfront Stadium (36-37) | 69-72 | |
| » W: Scott Scudder (4-6) L: Pete Smith (5-14) | Third | 12 out |
| Saturday, September 9 |
| » Lost to Braves (56-86), 2-1 | Riverfront Stadium (36-38) | 69-73 | |
| » W: Tom Glavine (13-8) L: Tim Leary (8-13) S: Dwayne Henry (1) | Third | 12 out |
| Sunday, September 10 |
| » Defeated Braves (56-87), 5-4 | Riverfront Stadium (37-38) | 70-73 | |
| » W: John Franco (4-7) L: Dwayne Henry (0-1) | Third | 12 out |
| » Major-league debuts: Tommy Greene (Braves) |
| Monday, September 11 |
| » Lost to Dodgers (68-76), 8-2 | Dodger Stadium (3-5) | 70-74 | |
| » W: Tim Belcher (12-12) L: Ron Robinson (4-2) | Fourth | 13 out |
| Tuesday, September 12 |
| » Lost to Dodgers (69-76), 5-4 | Dodger Stadium (3-6) | 70-75 | Lost 2 |
| » W: Jay Howell (5-3) L: Rob Dibble (8-5) | Fourth | 13 out |
| Wednesday, September 13 |
| » Lost to Giants (84-62), 8-7 | Candlestick Park (3-5) | 70-76 | Lost 3 |
| » W: Ernie Camacho (2-0) L: Rosario Rodriguez (1-1) | Fourth | 14 out |
| Thursday, September 14 |
| » Lost to Giants (85-62), 4-3 | Candlestick Park (3-6) | 70-77 | Lost 4 |
| » W: Ernie Camacho (3-0) L: Norm Charlton (6-2) | Fourth | 15 out |
| Friday, September 15 |
| » Lost to Astros (79-69), 4-1 | Astrodome (4-3) | 70-78 | Lost 5 |
| » W: Rick Rhoden (2-6) L: Jack Armstrong (2-2) S: Dave Smith (25) | Fourth | 15 out |
| Saturday, September 16 |
| » Lost to Astros (8 |