| Thursday, January 12 |
| Former Pirate Clise Dudley dies in Moncks Corner, SC at the age of 86. |
| Friday, February 24 |
| Former Pirate Sparky Adams dies in Pottsville, PA at the age of 95. |
| Wednesday, March 8 |
| Former Pirate Dale Coogan dies in Mission Viejo, CA at the age of 59. |
| Tuesday, April 4 |
| » Lost to Expos (1-0), 6-5 | Stade Olympique (0-1) | 0-1 | |
| » W: Andy McGaffigan (1-0) L: Jeff Robinson (0-1) | Second | 1 out |
| Wednesday, April 5 |
| » Defeated Expos (1-1), 3-0 | Stade Olympique (1-1) | 1-1 | |
| » W: Doug Drabek (1-0) L: Randy Johnson (0-1) | First | -- |
| » Major-league debuts: Gene Harris (Expos) |
| Thursday, April 6 |
| » Lost to Expos (2-1), 3-2 | Stade Olympique (1-2) | 1-2 | |
| » W: Tim Burke (1-0) L: John Smiley (0-1) S: Joe Hesketh (1) | Third | 1 out |
| Former Pirate Carlos Bernier dies in Juana Diaz, P.R. at the age of 63. |
| Friday, April 7 |
| » Lost to Cubs (2-2), 6-5 | Wrigley Field (0-1) | 1-3 | Lost 2 |
| » W: Steve Wilson (1-0) L: Dorn Taylor (0-1) S: Mitch Williams (2) | Sixth | 2 out |
| Saturday, April 8 |
| » Lost to Cubs (3-2), 5-3 | Wrigley Field (0-2) | 1-4 | Lost 3 |
| » W: Mike Bielecki (1-0) L: Neal Heaton (0-1) S: Calvin Schiraldi (1) | Sixth | 3 out |
| Sunday, April 9 |
| » Lost to Cubs (4-2), 8-3 | Wrigley Field (0-3) | 1-5 | Lost 4 |
| » W: Rick Sutcliffe (2-0) L: Bob Walk (0-1) | Fifth | 3 out |
| Tuesday, April 11 |
| » Defeated Mets (2-4), 4-3 | Three Rivers Stadium (1-0) | 2-5 | |
| » W: Jeff Robinson (1-1) L: Randy Myers (0-1) | Fifth | 3 out |
| Thursday, April 13 |
| » Defeated Mets (2-5), 4-2 | Three Rivers Stadium (2-0) | 3-5 | Won 2 |
| » W: John Smiley (1-1) L: Ron Darling (0-2) S: Jeff Robinson (1) | Third | 3 out |
| Friday, April 14 |
| » Lost to Expos (5-5), 7-6 | Three Rivers Stadium (2-1) | 3-6 | |
| » W: Joe Hesketh (1-0) L: Scott Medvin (0-1) S: Andy McGaffigan (1) | Fifth | 4 out |
| Saturday, April 15 |
| » Defeated Expos (5-6), 6-4 | Three Rivers Stadium (3-1) | 4-6 | |
| » W: Mike Dunne (1-0) L: Randy Johnson (0-2) S: Jeff Robinson (2) | Fourth | 3½ out |
| Sunday, April 16 |
| » Lost to Expos (6-6), 5-4 | Three Rivers Stadium (3-2) | 4-7 | |
| » W: Joe Hesketh (2-0) L: Jeff Robinson (1-2) S: Tim Burke (2) | Fifth | 4½ out |
| Monday, April 17 |
| » Lost to Cardinals (5-5), 4-2 | Busch Stadium II (0-1) | 4-8 | Lost 2 |
| » W: Scott Terry (1-1) L: Brian Fisher (0-1) S: Todd Worrell (2) | Sixth | 4½ out |
| Tuesday, April 18 |
| » Defeated Cardinals (5-6), 4-3 | Busch Stadium II (1-1) | 5-8 | |
| » W: Morris Madden (1-0) L: Todd Worrell (0-1) S: Jeff Robinson (3) | Fifth | 3½ out |
| Wednesday, April 19 |
| » Defeated Cardinals (5-7), 7-5 | Busch Stadium II (2-1) | 6-8 | Won 2 |
| » W: Bob Walk (1-1) L: Don Heinkel (0-1) S: Jeff Robinson (4) | Fourth | 2½ out |
| Thursday, April 20 |
| » Lost to Phillies (8-6), 9-4 | Three Rivers Stadium (3-3) | 6-9 | |
| » W: Ken Howell (2-0) L: Mike Dunne (1-1) | Fifth | 2½ out |
| Friday, April 21 |
| » Lost to Phillies (9-6), 3-2 | Three Rivers Stadium (3-4) | 6-10 | Lost 2 |
| » W: Floyd Youmans (1-2) L: Doug Drabek (1-1) S: Steve Bedrosian (2) | Fifth | 3½ out |
| Saturday, April 22 |
| » Defeated Phillies (9-7), 4-3 | Three Rivers Stadium (4-4) | 7-10 | |
| » W: Jeff Robinson (2-2) L: Don Carman (1-2) | Fifth | 2½ out |
| Sunday, April 23 |
| » Defeated Phillies (9-8), 6-4 | Three Rivers Stadium (5-4) | 8-10 | Won 2 |
| » W: Logan Easley (1-0) L: Steve Bedrosian (1-2) | Fifth | 1½ out |
| Tuesday, April 25 |
| » Lost to Padres (11-10), 1-0 | Three Rivers Stadium (5-5) | 8-11 | |
| » W: Eric Show (4-1) L: Bob Walk (1-2) S: Mark Davis (10) | Fifth | 2 out |
| Wednesday, April 26 |
| » Lost to Padres (12-10), 3-1 | Three Rivers Stadium (5-6) | 8-12 | Lost 2 |
| » W: Bruce Hurst (3-1) L: Doug Drabek (1-2) | Sixth | 2½ out |
| Thursday, April 27 |
| » Lost to Padres (13-10), 8-1 | Three Rivers Stadium (5-7) | 8-13 | Lost 3 |
| » W: Ed Whitson (3-2) L: Neal Heaton (0-2) | Fourth | 3 out |
| Friday, April 28 |
| » Defeated Giants (11-11), 1-0 | Three Rivers Stadium (6-7) | 9-13 | |
| » W: John Smiley (2-1) L: Rick Reuschel (3-2) | Fifth | 3 out |
| Saturday, April 29 |
| » Lost to Giants (12-11), 4-3 | Three Rivers Stadium (6-8) | 9-14 | |
| » W: Mike LaCoss (1-1) L: Jeff Robinson (2-3) | Fourth | 4 out |
| Sunday, April 30 |
| » Defeated Giants (12-12), 11-1 | Three Rivers Stadium (7-8) | 10-14 | |
| » W: Bob Walk (2-2) L: Don Robinson (1-2) | Sixth | 4 out |
| Monday, May 1 |
| » Lost to Dodgers (12-13), 1-0 | Dodger Stadium (0-1) | 10-15 | |
| » W: Jay Howell (2-2) L: Doug Drabek (1-3) | Sixth | 5 out |
| Tuesday, May 2 |
| » Lost to Dodgers (13-13), 7-0 | Dodger Stadium (0-2) | 10-16 | Lost 2 |
| » W: Orel Hershiser (4-2) L: Neal Heaton (0-3) | Fifth | 5 out |
| Wednesday, May 3 |
| » Defeated Giants (13-14), 5-3 | Candlestick Park (1-0) | 11-16 | |
| » W: John Smiley (3-1) L: Don Robinson (1-3) S: Logan Easley (1) | Fifth | 4 out |
| Thursday, May 4 |
| » Lost to Giants (14-14), 6-3 | Candlestick Park (1-1) | 11-17 | |
| » W: Mike Krukow (1-0) L: Randy Kramer (0-1) S: Craig Lefferts (4) | Fifth | 5 out |
| Friday, May 5 |
| » Defeated Padres (15-16), 4-2 | San Diego/Jack Murphy Stadium (1-0) | 12-17 | |
| » W: Bob Walk (3-2) L: Eric Show (4-3) | Sixth | 5 out |
| Saturday, May 6 |
| » Lost to Padres (16-16), 4-2 | San Diego/Jack Murphy Stadium (1-1) | 12-18 | |
| » W: Bruce Hurst (4-2) L: Doug Drabek (1-4) S: Mark Davis (12) | Sixth | 5½ out |
| Sunday, May 7 |
| » Lost to Padres (17-16), 3-1 | San Diego/Jack Murphy Stadium (1-2) | 12-19 | Lost 2 |
| » W: Ed Whitson (5-2) L: Neal Heaton (0-4) S: Mark Davis (13) | Sixth | 5½ out |
| Wednesday, May 10 |
| » Major-league debuts: Steve Frey (Expos) |
| Friday, May 12 |
| » Defeated Braves (17-18), 10-2 | Three Rivers Stadium (8-8) | 13-19 | |
| » W: John Smiley (4-1) L: Zane Smith (1-5) | Sixth | 5½ out |
| Saturday, May 13 |
| » Defeated Braves (17-19), 8-3 | Three Rivers Stadium (9-8) | 14-19 | Won 2 |
| » W: Bob Walk (4-2) L: Pete Smith (1-5) | Sixth | 5 out |
| Sunday, May 14 |
| » Lost to Braves (18-19), 5-2 | Three Rivers Stadium (9-9) | 14-20 | |
| » W: John Smoltz (6-2) L: Doug Drabek (1-5) S: Joe Boever (5) | Sixth | 6 out |
| Monday, May 15 |
| » Lost to Reds (21-15), 6-5 | Riverfront Stadium (0-1) | 14-21 | Lost 2 |
| » W: Norm Charlton (2-0) L: Jeff Robinson (2-4) | Sixth | 6 out |
| Tuesday, May 16 |
| » Defeated Reds (21-16), 5-0 | Riverfront Stadium (1-1) | 15-21 | |
| » W: Randy Kramer (1-1) L: Rick Mahler (5-4) | Sixth | 5½ out |
| Wednesday, May 17 |
| » Lost to Reds (22-16), 5-4 | Riverfront Stadium (1-2) | 15-22 | |
| » W: John Franco (1-0) L: Bill Landrum (0-1) | Sixth | 5½ out |
| Friday, May 19 |
| » Lost to Astros (20-20), 3-0 | Astrodome (0-1) | 15-23 | Lost 2 |
| » W: Mike Scott (6-2) L: Bob Walk (4-3) | Sixth | 7 out |
| Saturday, May 20 |
| » Lost to Astros (21-20), 5-4 | Astrodome (0-2) | 15-24 | Lost 3 |
| » W: Juan Agosto (1-1) L: Bob Kipper (0-1) | Sixth | 7 out |
| Sunday, May 21 |
| » Defeated Astros (21-21), 17-5 | Astrodome (1-2) | 16-24 | |
| » W: Neal Heaton (1-4) L: Jim Clancy (1-4) S: Brian Fisher (1) | Fifth | 6 out |
| Tuesday, May 23 |
| » Defeated Braves (19-25), 5-2 | Atlanta-Fulton County Stadium (1-0) | 17-24 | Won 2 |
| » W: John Smiley (5-1) L: Zane Smith (1-7) | Sixth | 6 out |
| Wednesday, May 24 |
| » Defeated Braves (19-26), 4-1 | Atlanta-Fulton County Stadium (2-0) | 18-24 | Won 3 |
| » W: Bill Landrum (1-1) L: Jim Acker (0-2) | Fifth | 6 out |
| » Major-league debuts: David Justice (Braves) |
| Thursday, May 25 |
| » Defeated Braves (19-27), 7-3 | Atlanta-Fulton County Stadium (3-0) | 19-24 | Won 4 |
| » W: Doug Drabek (2-5) L: Pete Smith (1-6) S: Bill Landrum (1) | Fifth | 5½ out |
| Friday, May 26 |
| » Lost to Astros (22-24), 4-2 | Three Rivers Stadium (9-10) | 19-25 | |
| » W: Jim Clancy (2-4) L: Neal Heaton (1-5) S: Dave Smith (7) | Fifth | 5½ out |
| Saturday, May 27 |
| » Lost to Astros (23-24), 5-4 | Three Rivers Stadium (9-11) | 19-26 | Lost 2 |
| » W: Dan Schatzeder (2-0) L: Jeff Robinson (2-5) S: Dave Smith (8) | Fifth | 6½ out |
| Sunday, May 28 |
| » Lost to Astros (24-24), 9-2 | Three Rivers Stadium (9-12) | 19-27 | Lost 3 |
| » W: Mike Scott (7-3) L: John Smiley (5-2) S: Juan Agosto (1) | Fifth | 7½ out |
| Monday, May 29 |
| » Defeated Reds (26-21), 12-3 | Three Rivers Stadium (10-12) | 20-27 | |
| » W: Bob Walk (5-3) L: Tom Browning (4-5) S: Bob Kipper (1) | Fifth | 6½ out |
| Tuesday, May 30 |
| » Defeated Reds (26-22), 2-0 | Three Rivers Stadium (11-12) | 21-27 | Won 2 |
| » W: Doug Drabek (3-5) L: Rick Mahler (6-5) S: Randy Kramer (1) | Fifth | 6½ out |
| Wednesday, May 31 |
| » Lost to Reds (27-22), 4-3 | Three Rivers Stadium (11-13) | 21-28 | |
| » W: Jose Rijo (5-1) L: Neal Heaton (1-6) S: John Franco (15) | Fifth | 6½ out |
| Friday, June 2 |
| » Lost to Mets (26-24), 3-2 | Shea Stadium (0-1) | 21-29 | Lost 2 |
| » W: Rick Aguilera (2-1) L: Randy Kramer (1-2) | Fifth | 7½ out |
| » Major-league debuts: Jeff King (Pirates) |
| Saturday, June 3 |
| » Lost to Mets (27-24), 9-3 | Shea Stadium (0-2) | 21-30 | Lost 3 |
| » W: Ron Darling (4-4) L: Bob Walk (5-4) | Fifth | 7½ out |
| Sunday, June 4 |
| » Lost to Mets (28-24), 4-3 | Shea Stadium (0-3) | 21-31 | Lost 4 |
| » W: Don Aase (1-1) L: Bob Kipper (0-2) S: Randy Myers (8) | Fifth | 8½ out |
| Monday, June 5 |
| » Tied Phillies, 3-3 | Veteran's Stadium (0-0) | 21-31 | |
| » Starters: Neal Heaton vs Bruce Ruffin | Fifth | 9 out |
| Tuesday, June 6 |
| » Lost to Phillies (19-34), 9-4 | Veteran's Stadium (0-1) | 21-32 | Lost 5 |
| » W: Bob Sebra (2-1) L: Brian Fisher (0-2) S: Jeff Parrett (1) | Fifth | 10 out |
| Former Pirate Whitey Glazner dies in Orlando, FL at the age of 96. |
| Wednesday, June 7 |
| » Lost to Phillies (20-34), 7-5 | Veteran's Stadium (0-2) | 21-33 | Lost 6 |
| » W: Jeff Parrett (2-2) L: Bob Kipper (0-3) S: Steve Bedrosian (6) | Fifth | 10 out |
| Thursday, June 8 |
| » Lost to Phillies (21-34), 15-11 | Veteran's Stadium (0-3) | 21-34 | Lost 7 |
| » W: Don Carman (2-9) L: Jeff Robinson (2-6) | Fifth | 11 out |
| Friday, June 9 |
| » Defeated Mets (29-28), 4-3 | Three Rivers Stadium (12-13) | 22-34 | |
| » W: Bill Landrum (2-1) L: Roger McDowell (1-5) | Fifth | 10 out |
| Saturday, June 10 |
| » Defeated Mets (29-29), 6-5 | Three Rivers Stadium (13-13) | 23-34 | Won 2 |
| » W: Bob Kipper (1-3) L: Randy Myers (5-2) | Fifth | 9 out |
| Sunday, June 11 |
| » Lost to Mets (30-29), 6-1 | Three Rivers Stadium (13-14) | 23-35 | |
| » W: Bob Ojeda (3-6) L: Brian Fisher (0-3) | Fifth | 9 out |
| Tuesday, June 13 |
| » Lost to Phillies (22-37), 10-2 | Three Rivers Stadium (13-15) | 23-36 | Lost 2 |
| » W: Ken Howell (6-3) L: Morris Madden (1-1) | Fourth | 10½ out |
| Wednesday, June 14 |
| » Defeated Phillies (22-38), 6-4 | Three Rivers Stadium (14-15) | 24-36 | |
| » W: John Smiley (6-2) L: Don Carman (2-10) S: Bill Landrum (2) | Fourth | 9½ out |
| Thursday, June 15 |
| » Defeated Phillies (22-39), 5-3 | Three Rivers Stadium (15-15) | 25-36 | Won 2 |
| » W: Doug Drabek (4-5) L: Bob Sebra (2-3) S: Bill Landrum (3) | Fourth | 8½ out |
| Friday, June 16 |
| » Lost to Cardinals (33-30), 6-2 | Busch Stadium II (2-2) | 25-37 | |
| » W: Scott Terry (5-6) L: Randy Kramer (1-3) S: Ken Dayley (4) | Fourth | 9 out |
| Saturday, June 17 |
| » Defeated Cardinals (33-31), 7-2 | Busch Stadium II (3-2) | 26-37 | |
| » W: Jeff Robinson (3-6) L: Jose DeLeon (8-5) S: Bob Kipper (2) | Fifth | 8½ out |
| Sunday, June 18 |
| » Defeated Cardinals (33-32), 12-4 | Busch Stadium II (4-2) | 27-37 | Won 2 |
| » W: Morris Madden (2-1) L: Joe Magrane (5-6) S: Bill Landrum (4) | Fifth | 8½ out |
| Tuesday, June 20 |
| » Lost to Cubs (38-30), 5-4 | Three Rivers Stadium (15-16) | 27-38 | |
| » W: Calvin Schiraldi (2-4) L: Miguel Garcia (0-1) S: Paul Kilgus (1) | Fourth | 9½ out |
| Wednesday, June 21 |
| » Lost to Cubs (39-30), 1-0 | Three Rivers Stadium (15-17) | 27-39 | Lost 2 |
| » W: Greg Maddux (6-6) L: Doug Bair (0-1) S: Mitch Williams (18) | Fifth | 10½ out |
| Thursday, June 22 |
| » Lost to Cubs (40-30), 8-0 | Three Rivers Stadium (15-18) | 27-40 | Lost 3 |
| » W: Rick Sutcliffe (9-4) L: Randy Kramer (1-4) | Fifth | 11½ out |
| Friday, June 23 |
| » Lost to Cardinals (36-33), 3-2 | Three Rivers Stadium (15-19) | 27-41 | Lost 4 |
| » W: Joe Magrane (6-6) L: Morris Madden (2-2) S: Todd Worrell (9) | Fifth | 11½ out |
| Saturday, June 24 |
| » Defeated Cardinals (36-34), 5-2 | Three Rivers Stadium (16-19) | 28-41 | |
| » W: Bob Walk (6-4) L: Scott Terry (5-7) S: Bill Landrum (5) | Fifth | 10½ out |
| Sunday, June 25 |
| » Defeated Cardinals (36-35), 5-3 | Three Rivers Stadium (17-19) | 29-41 | Won 2 |
| » W: John Smiley (7-2) L: Ted Power (0-2) S: Bill Landrum (6) | Fifth | 9½ out |
| Monday, June 26 |
| » Defeated Cubs (40-34), 2-1 | Wrigley Field (1-3) | 30-41 | Won 3 |
| » W: Doug Drabek (5-5) L: Greg Maddux (6-7) | Fifth | 9 out |
| Tuesday, June 27 |
| » Defeated Cubs (40-35), 5-4 | Wrigley Field (2-3) | 31-41 | Won 4 |
| » W: Randy Kramer (2-4) L: Rick Sutcliffe (9-5) S: Bill Landrum (7) | Fifth | 9 out |
| Wednesday, June 28 |
| » Defeated Cubs (40-36), 3-1 | Wrigley Field (3-3) | 32-41 | Won 5 |
| » W: Jeff Robinson (4-6) L: Mike Bielecki (6-4) S: Bill Landrum (8) | Fifth | 9 out |
| Friday, June 30 |
| » Defeated Dodgers (37-41), 4-3 | Dodger Stadium (1-2) | 33-41 | Won 6 |
| » W: Bob Walk (7-4) L: Orel Hershiser (9-7) S: Bill Landrum (9) | Fifth | 8½ out |
| Saturday, July 1 |
| » Lost to Dodgers (38-41), 1-0 | Dodger Stadium (1-3) | 33-42 | |
| » W: Tim Belcher (5-8) L: John Smiley (7-3) | Fifth | 8½ out |
| Sunday, July 2 |
| » Lost to Dodgers (39-41), 3-2 | Dodger Stadium (1-4) | 33-43 | Lost 2 |
| » W: John Wetteland (2-0) L: Doug Drabek (5-6) S: Jay Howell (15) | Fifth | 9½ out |
| Monday, July 3 |
| » Defeated Dodgers (39-42), 4-2 | Dodger Stadium (2-4) | 34-43 | |
| » W: Jeff Robinson (5-6) L: Mike Morgan (5-8) S: Bill Landrum (10) | Fifth | 9½ out |
| Tuesday, July 4 |
| » Defeated Giants (48-34), 5-3 | Three Rivers Stadium (18-19) | 35-43 | Won 2 |
| » W: Randy Kramer (3-4) L: Don Robinson (7-6) S: Bill Landrum (11) | Fifth | 8½ out |
| Wednesday, July 5 |
| » Lost to Giants (49-34), 6-4 | Three Rivers Stadium (18-20) | 35-44 | |
| » W: Trevor Wilson (1-1) L: Bob Walk (7-5) | Fifth | 9½ out |
| Thursday, July 6 |
| » Lost to Giants (50-34), 2-1 | Three Rivers Stadium (18-21) | 35-45 | Lost 2 |
| » W: Jeff Brantley (3-0) L: John Smiley (7-4) S: Craig Lefferts (15) | Fifth | 10 out |
| Friday, July 7 |
| » Defeated Padres (40-46), 3-0 | Three Rivers Stadium (19-21) | 36-45 | |
| » W: Doug Drabek (6-6) L: Bruce Hurst (7-6) | Fifth | 10 out |
| Saturday, July 8 |
| » Lost to Padres (41-46), 2-0 | Three Rivers Stadium (19-22) | 36-46 | |
| » W: Ed Whitson (11-6) L: Jeff Robinson (5-7) | Fifth | 10 out |
| Sunday, July 9 |
| » Lost to Padres (42-46), 5-3 | Three Rivers Stadium (19-23) | 36-47 | Lost 2 |
| » W: Mark Grant (3-1) L: Randy Kramer (3-5) S: Mark Davis (22) | Fifth | 11 out |
| Thursday, July 13 |
| » Lost to Giants (52-36), 3-2 | Candlestick Park (1-2) | 36-48 | Lost 3 |
| » W: Jeff Brantley (5-0) L: Miguel Garcia (0-2) | Fifth | 12 out |
| Friday, July 14 |
| » Defeated Giants (52-37), 7-4 | Candlestick Park (2-2) | 37-48 | |
| » W: Doug Drabek (7-6) L: Rick Reuschel (12-4) S: Bill Landrum (12) | Fifth | 12 out |
| Saturday, July 15 |
| » Lost to Giants (53-37), 8-3 | Candlestick Park (2-3) | 37-49 | |
| » W: Mike LaCoss (4-6) L: John Smiley (7-5) | Fifth | 12 out |
| Sunday, July 16 |
| » Lost to Giants (54-37), 3-1 | Candlestick Park (2-4) | 37-50 | Lost 2 |
| » W: Scott Garrelts (7-3) L: Jeff Robinson (5-8) S: Steve Bedrosian (13) | Fifth | 13 out |
| Monday, July 17 |
| » Defeated Padres (45-48), 4-1 | San Diego/Jack Murphy Stadium (2-2) | 38-50 | |
| » W: Randy Kramer (4-5) L: Greg Harris (3-4) S: Bill Landrum (13) | Fifth | 13 out |
| Tuesday, July 18 |
| » Lost to Padres (46-48), 17-4 | San Diego/Jack Murphy Stadium (2-3) | 38-51 | |
| » W: Bruce Hurst (8-7) L: Bob Walk (7-6) | Fifth | 13 out |
| Wednesday, July 19 |
| » Lost to Padres (47-48), 9-1 | San Diego/Jack Murphy Stadium (2-4) | 38-52 | Lost 2 |
| » W: Ed Whitson (13-6) L: Doug Drabek (7-7) | Fifth | 13 out |
| Friday, July 21 |
| » Defeated Dodgers (43-52), 4-1 | Three Rivers Stadium (20-23) | 39-52 | |
| » W: John Smiley (8-5) L: Tim Belcher (6-9) | Fifth | 14 out |
| » Lost to Dodgers (44-52), 7-3 | Three Rivers Stadium (20-24) | 39-53 | |
| » W: Fernando Valenzuela (5-9) L: Neal Heaton (1-7) S: Jay Howell (18) | Fifth | 14 out |
| Saturday, July 22 |
| » Lost to Dodgers (45-52), 8-4 | Three Rivers Stadium (20-25) | 39-54 | Lost 2 |
| » W: Ramon Martinez (2-0) L: Jeff Robinson (5-9) | Fifth | 15 out |
| Sunday, July 23 |
| » Lost to Dodgers (46-52), 4-3 | Three Rivers Stadium (20-26) | 39-55 | Lost 3 |
| » W: Orel Hershiser (12-7) L: Randy Kramer (4-6) S: Jay Howell (19) | Fifth | 15½ out |
| » Defeated Dodgers (46-53), 2-1 | Three Rivers Stadium (21-26) | 40-55 | |
| » W: Bob Kipper (2-3) L: Tim Crews (0-1) | Fifth | 15½ out |
| Monday, July 24 |
| » Defeated Dodgers (46-54), 7-4 | Three Rivers Stadium (22-26) | 41-55 | Won 2 |
| » W: Bob Walk (8-6) L: Mike Morgan (6-11) | Fifth | 15½ out |
| Tuesday, July 25 |
| » Defeated Mets (53-44), 4-2 | Shea Stadium (1-3) | 42-55 | Won 3 |
| » W: Doug Drabek (8-7) L: Rick Aguilera (6-4) S: Bill Landrum (14) | Fifth | 15½ out |
| Wednesday, July 26 |
| » Defeated Mets (53-45), 3-2 | Shea Stadium (2-3) | 43-55 | Won 4 |
| » W: John Smiley (9-5) L: Ron Darling (8-8) | Fifth | 14½ out |
| Thursday, July 27 |
| » Defeated Mets (53-46), 10-8 | Shea Stadium (3-3) | 44-55 | Won 5 |
| » W: Bob Kipper (3-3) L: Don Aase (1-3) S: Bill Landrum (15) | Fifth | 14 out |
| Friday, July 28 |
| » Defeated Phillies (38-61), 10-5 | Veteran's Stadium (1-3) | 45-55 | Won 6 |
| » W: Neal Heaton (2-7) L: Ken Howell (8-7) | Fifth | 13½ out |
| » Lost to Phillies (39-61), 6-1 | Veteran's Stadium (1-4) | 45-56 | |
| » W: Greg Harris (2-2) L: Rick Reed (0-1) | Fifth | 13½ out |
| Saturday, July 29 |
| » Lost to Phillies (40-61), 6-2 | Veteran's Stadium (1-5) | 45-57 | Lost 2 |
| » W: Jeff Parrett (8-3) L: Bob Walk (8-7) S: Roger McDowell (12) | Fifth | 14½ out |
| Sunday, July 30 |
| » Lost to Phillies (41-61), 8-6 | Veteran's Stadium (1-6) | 45-58 | Lost 3 |
| » W: Dennis Cook (5-3) L: Bob Kipper (3-4) S: Roger McDowell (13) | Fifth | 14½ out |
| Monday, July 31 |
| » Lost to Expos (61-44), 4-2 | Three Rivers Stadium (22-27) | 45-59 | Lost 4 |
| » W: Mark Langston (13-8) L: John Smiley (9-6) S: Tim Burke (22) | Fifth | 15½ out |
| Tuesday, August 1 |
| » Lost to Expos (62-44), 5-4 | Three Rivers Stadium (22-28) | 45-60 | Lost 5 |
| » W: Tim Burke (6-1) L: Doug Bair (0-2) | Fifth | 16½ out |
| Wednesday, August 2 |
| » Lost to Expos (63-44), 3-1 | Three Rivers Stadium (22-29) | 45-61 | Lost 6 |
| » W: Pascual Perez (6-10) L: Rick Reed (0-2) S: Tim Burke (23) | Fifth | 17½ out |
| Thursday, August 3 |
| » Defeated Expos (63-45), 1-0 | Three Rivers Stadium (23-29) | 46-61 | |
| » W: Doug Bair (1-2) L: Andy McGaffigan (3-5) | Fifth | 16½ out |
| Friday, August 4 |
| » Lost to Cubs (62-47), 3-2 | Three Rivers Stadium (23-30) | 46-62 | |
| » W: Mike Bielecki (11-5) L: Doug Drabek (8-8) S: Mitch Williams (28) | Fifth | 16½ out |
| Saturday, August 5 |
| » Lost to Cubs (63-47), 4-2 | Three Rivers Stadium (23-31) | 46-63 | Lost 2 |
| » W: Steve Wilson (5-0) L: Bill Landrum (2-2) S: Les Lancaster (4) | Fourth | 16½ out |
| Sunday, August 6 |
| » Defeated Cubs (63-48), 5-4 | Three Rivers Stadium (24-31) | 47-63 | |
| » W: Doug Drabek (9-8) L: Scott Sanderson (9-8) | Fourth | 15½ out |
| Monday, August 7 |
| » Lost to Cardinals (58-50), 4-0 | Three Rivers Stadium (24-32) | 47-64 | |
| » W: Ted Power (4-4) L: Rick Reed (0-3) | Fifth | 16½ out |
| Tuesday, August 8 |
| » Defeated Cardinals (58-51), 7-3 | Three Rivers Stadium (25-32) | 48-64 | |
| » W: Bob Walk (9-7) L: Ken Hill (6-8) | Fifth | 16½ out |
| Wednesday, August 9 |
| » Lost to Cardinals (59-51), 5-2 | Three Rivers Stadium (25-33) | 48-65 | |
| » W: Joe Magrane (14-7) L: Doug Drabek (9-9) | Fifth | 17½ out |
| Friday, August 11 |
| » Lost to Expos (64-51), 4-1 | Stade Olympique (1-3) | 48-66 | Lost 2 |
| » W: Mark Langston (14-8) L: John Smiley (9-7) | Fifth | 18 out |
| Saturday, August 12 |
| » Lost to Expos (65-51), 5-2 | Stade Olympique (1-4) | 48-67 | Lost 3 |
| » W: Kevin Gross (9-8) L: Jeff Robinson (5-10) S: Zane Smith (2) | Fifth | 19 out |
| Sunday, August 13 |
| » Defeated Expos (65-52), 6-4 | Stade Olympique (2-4) | 49-67 | |
| » W: Bob Walk (10-7) L: Pascual Perez (6-12) S: Bill Landrum (16) | Fifth | 18 out |
| Monday, August 14 |
| » Defeated Expos (65-53), 6-1 | Stade Olympique (3-4) | 50-67 | Won 2 |
| » W: Doug Drabek (10-9) L: Dennis Martinez (12-3) | Fifth | 17½ out |
| Tuesday, August 15 |
| » Lost to Astros (65-54), 3-2 | Astrodome (1-3) | 50-68 | |
| » W: Larry Andersen (3-3) L: Mike Smith (0-1) | Fifth | 18½ out |
| Wednesday, August 16 |
| » Defeated Astros (65-55), 5-4 | Astrodome (2-3) | 51-68 | |
| » W: Neal Heaton (3-7) L: Larry Andersen (3-4) S: Bill Landrum (17) | Fifth | 18½ out |
| Thursday, August 17 |
| » Lost to Astros (66-55), 5-3 | Astrodome (2-4) | 51-69 | |
| » W: Jim Deshaies (11-6) L: Jeff Robinson (5-11) | Fifth | 19½ out |
| Friday, August 18 |
| » Lost to Braves (49-73), 13-6 | Atlanta-Fulton County Stadium (3-1) | 51-70 | Lost 2 |
| » W: Tom Glavine (12-6) L: Bob Walk (10-8) | Fifth | 19½ out |
| Saturday, August 19 |
| » Lost to Braves (50-73), 4-3 | Atlanta-Fulton County Stadium (3-2) | 51-71 | Lost 3 |
| » W: John Smoltz (12-11) L: Doug Drabek (10-10) S: Joe Boever (20) | Fifth | 19½ out |
| Sunday, August 20 |
| » Defeated Braves (50-74), 7-6 | Atlanta-Fulton County Stadium (4-2) | 52-71 | |
| » W: Rick Reed (1-3) L: Pete Smith (3-13) S: Bill Landrum (18) | Fifth | 18½ out |
| Monday, August 21 |
| Former Pirate Ted Wilks dies in Houston, TX at the age of 74. |
| Tuesday, August 22 |
| » Defeated Astros (69-56), 4-1 | Three Rivers Stadium (26-33) | 53-71 | Won 2 |
| » W: John Smiley (10-7) L: Jim Deshaies (11-7) | Fifth | 17 out |
| Wednesday, August 23 |
| » Defeated Astros (69-57), 6-1 | Three Rivers Stadium (27-33) | 54-71 | Won 3 |
| » W: Bob Walk (11-8) L: Jim Clancy (6-11) | Fifth | 16 out |
| Thursday, August 24 |
| » Defeated Astros (69-58), 3-2 | Three Rivers Stadium (28-33) | 55-71 | Won 4 |
| » W: Doug Bair (2-2) L: Juan Agosto (3-5) | Fifth | 15½ out |
| Friday, August 25 |
| » Defeated Reds (61-67), 12-3 | Riverfront Stadium (2-2) | 56-71 | Won 5 |
| » W: Jeff Robinson (6-11) L: Rick Mahler (9-13) | Fourth | 15½ out |
| Saturday, August 26 |
| » Lost to Reds (62-67), 6-4 | Riverfront Stadium (2-3) | 56-72 | |
| » W: Ron Robinson (3-1) L: Rick Reed (1-4) S: John Franco (27) | Fifth | 15½ out |
| Sunday, August 27 |
| » Lost to Reds (63-67), 1-0 | Riverfront Stadium (2-4) | 56-73 | Lost 2 |
| » W: Tom Browning (14-10) L: Randy Kramer (4-7) S: John Franco (28) | Fifth | 16½ out |
| Monday, August 28 |
| » Lost to Braves (53-78), 5-2 | Three Rivers Stadium (28-34) | 56-74 | Lost 3 |
| » W: Pete Smith (4-13) L: Bob Walk (11-9) S: Mike Stanton (1) | Fifth | 17½ out |
| Former Pirate Fred Waters dies in Pensacola, FL at the age of 63. |
| Tuesday, August 29 |
| » Defeated Braves (53-79), 5-4 | Three Rivers Stadium (29-34) | 57-74 | |
| » W: Doug Drabek (11-10) L: Tom Glavine (12-8) S: Bill Landrum (19) | Fifth | 17½ out |
| Wednesday, August 30 |
| » Defeated Braves (53-80), 7-5 | Three Rivers Stadium (30-34) | 58-74 | Won 2 |
| » W: Randy Kramer (5-7) L: Joe Boever (4-6) S: Bill Landrum (20) | Fourth | 16½ out |
| Friday, September 1 |
| » Lost to Reds (65-69), 11-5 | Three Rivers Stadium (30-35) | 58-75 | |
| » W: Ron Robinson (4-1) L: Bob Patterson (0-1) | Fourth | 16½ out |
| » Major-league debuts: Rosario Rodriguez (Reds) |
| Saturday, September 2 |
| » Lost to Reds (66-69), 6-2 | Three Rivers Stadium (30-36) | 58-76 | Lost 2 |
| » W: Tom Browning (15-10) L: Bob Walk (11-10) | Fifth | 17½ out |
| Sunday, September 3 |
| » Defeated Reds (66-70), 3-1 | Three Rivers Stadium (31-36) | 59-76 | |
| » W: Doug Drabek (12-10) L: Scott Scudder (3-6) S: Bill Landrum (21) | Fifth | 16½ out |
| Former Pirate Rip Sewell dies in Plant City, FL at the age of 83. |
| Monday, September 4 |
| » Defeated Phillies (54-82), 7-5 | Veteran's Stadium (2-6) | 60-76 | Won 2 |
| » W: Bob Patterson (1-1) L: Mike Maddux (1-3) S: Bill Landrum (22) | Fifth | 16½ out |
| » Major-league debuts: Chuck McElroy (Phillies) |
| Tuesday, September 5 |
| » Lost to Phillies (55-82), 3-2 | Veteran's Stadium (2-7) | 60-77 | |
| » W: Jeff Parrett (12-4) L: Bob Patterson (1-2) | Fifth | 16½ out |
| » Major-league debuts: Pat Combs (Phillies) |
| Wednesday, September 6 |
| » Lost to Expos (75-64), 11-6 | Stade Olympique (3-5) | 60-78 | Lost 2 |
| » W: Mark Langston (15-11) L: Randy Kramer (5-8) | Fifth | 16½ out |
| Thursday, September 7 |
| » Defeated Expos (75-65), 7-4 | Stade Olympique (4-5) | 61-78 | |
| » W: Bob Walk (12-10) L: John Candelaria (3-4) S: Bill Landrum (23) | Fifth | 16½ out |
| Friday, September 8 |
| » Lost to Mets (75-65), 7-2 | Shea Stadium (3-4) | 61-79 | |
| » W: Bob Ojeda (11-10) L: Doug Drabek (12-11) | Fifth | 16½ out |
| » Major-league debuts: Stan Belinda (Pirates) |
| Saturday, September 9 |
| » Defeated Mets (75-66), 8-5 | Shea Stadium (4-4) | 62-79 | |
| » W: Dorn Taylor (1-1) L: Jeff Innis (0-1) S: Bob Patterson (1) | Fifth | 16½ out |
| Sunday, September 10 |
| » Defeated Mets (75-67), 4-1 | Shea Stadium (5-4) | 63-79 | Won 2 |
| » W: John Smiley (11-7) L: Sid Fernandez (11-4) S: Bob Kipper (3) | Fifth | 16½ out |
| Monday, September 11 |
| » Defeated Cardinals (77-66), 3-1 | Busch Stadium II (5-2) | 64-79 | Won 3 |
| » W: Neal Heaton (4-7) L: Ricky Horton (0-2) S: Doug Bair (1) | Fifth | 16½ out |
| Tuesday, September 12 |
| » Defeated Cardinals (77-67), 5-2 | Busch Stadium II (6-2) | 65-79 | Won 4 |
| » W: Bob Walk (13-10) L: Joe Magrane (18-8) | Fifth | 16½ out |
| Wednesday, September 13 |
| » Tied Cardinals, 0-0 | Busch Stadium II (6-2) | 65-79 | |
| » Starters: Doug Drabek vs Jose DeLeon | Fifth | 17 out |
| Thursday, September 14 |
| » Defeated Cardinals (77-68), 4-3 | Busch Stadium II (7-2) | 66-79 | Won 5 |
| » W: Bob Patterson (2-2) L: Ken Dayley (3-3) S: Bob Kipper (4) | Fourth | 16½ out |
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