| Tuesday, April 5 |
| » Defeated Twins (0-1), 8-0 | Yankee Stadium (1-0) | 1-0 | |
| » W: Rick Rhoden (1-0) L: Frank Viola (0-1) | First | -- |
| Wednesday, April 6 |
| » Defeated Twins (0-2), 5-3 | Yankee Stadium (2-0) | 2-0 | Won 2 |
| » W: Cecilio Guante (1-0) L: Juan Berenguer (0-1) S: Dave Righetti (1) | First | -- |
| Friday, April 8 |
| » Defeated Brewers (2-1), 6-4 | Yankee Stadium (3-0) | 3-0 | Won 3 |
| » W: Richard Dotson (1-0) L: Juan Nieves (0-1) S: Dave Righetti (2) | First | -- |
| Saturday, April 9 |
| » Defeated Brewers (2-2), 4-1 | Yankee Stadium (4-0) | 4-0 | Won 4 |
| » W: Al Leiter (1-0) L: Bill Wegman (0-1) S: Dave Righetti (3) | First | -- |
| Sunday, April 10 |
| » Defeated Brewers (2-3), 7-6 | Yankee Stadium (5-0) | 5-0 | Won 5 |
| » W: Tim Stoddard (1-0) L: Chuck Crim (0-1) S: Cecilio Guante (1) | First | -- |
| Monday, April 11 |
| » Lost to Blue Jays (4-3), 17-9 | Exhibition Stadium (0-1) | 5-1 | |
| » W: David Wells (1-0) L: Rick Rhoden (1-1) | Second | ½ out |
| Tuesday, April 12 |
| » Defeated Blue Jays (4-4), 12-3 | Exhibition Stadium (1-1) | 6-1 | |
| » W: John Candelaria (1-0) L: Jim Clancy (0-2) | First | -- |
| Wednesday, April 13 |
| » Defeated Blue Jays (4-5), 5-1 | Exhibition Stadium (2-1) | 7-1 | Won 2 |
| » W: Richard Dotson (2-0) L: Dave Stieb (0-2) | First | -- |
| Thursday, April 14 |
| » Defeated Blue Jays (4-6), 7-3 | Exhibition Stadium (3-1) | 8-1 | Won 3 |
| » W: Al Leiter (2-0) L: Jimmy Key (2-1) | First | -- |
| Friday, April 15 |
| » Defeated Brewers (2-7), 7-1 | County Stadium (1-0) | 9-1 | Won 4 |
| » W: Tommy John (1-0) L: Mike Birkbeck (0-1) | First | -- |
| Saturday, April 16 |
| » Lost to Brewers (3-7), 9-2 | County Stadium (1-1) | 9-2 | |
| » W: Chris Bosio (2-1) L: Rick Rhoden (1-2) | Second | ½ out |
| Sunday, April 17 |
| » Lost to Brewers (4-7), 6-3 | County Stadium (1-2) | 9-3 | Lost 2 |
| » W: Teddy Higuera (2-0) L: John Candelaria (1-1) S: Dan Plesac (1) | Second | 1½ out |
| Monday, April 18 |
| » Defeated Twins (4-7), 18-5 | Hubert H. Humphrey Metrodome (1-0) | 10-3 | |
| » W: Charles Hudson (1-0) L: Bert Blyleven (1-1) | Second | 1 out |
| Tuesday, April 19 |
| » Defeated Twins (4-8), 7-6 | Hubert H. Humphrey Metrodome (2-0) | 11-3 | Won 2 |
| » W: Al Leiter (3-0) L: Joe Niekro (1-1) S: Dave Righetti (4) | First | -- |
| Wednesday, April 20 |
| » Defeated Twins (4-9), 7-6 | Hubert H. Humphrey Metrodome (3-0) | 12-3 | Won 3 |
| » W: Dave Righetti (1-0) L: Jeff Reardon (0-1) | First | -- |
| Friday, April 22 |
| » Lost to Blue Jays (8-7), 6-4 | Yankee Stadium (5-1) | 12-4 | |
| » W: David Wells (2-1) L: Tim Stoddard (1-1) S: Tom Henke (4) | Second | 1 out |
| Saturday, April 23 |
| » Lost to Blue Jays (9-7), 3-2 | Yankee Stadium (5-2) | 12-5 | Lost 2 |
| » W: John Cerutti (1-0) L: John Candelaria (1-2) S: Tom Henke (5) | Second | 2 out |
| Sunday, April 24 |
| » Defeated Blue Jays (9-8), 5-3 | Yankee Stadium (6-2) | 13-5 | |
| » W: Charles Hudson (2-0) L: Mark Eichhorn (0-1) | Second | 1 out |
| Tuesday, April 26 |
| » Defeated Royals (9-9), 5-4 | Yankee Stadium (7-2) | 14-5 | Won 2 |
| » W: Cecilio Guante (2-0) L: Charlie Leibrandt (1-4) S: Charles Hudson (1) | Second | 1 out |
| Wednesday, April 27 |
| » Lost to Royals (10-9), 3-1 | Yankee Stadium (7-3) | 14-6 | |
| » W: Bud Black (1-1) L: Charles Hudson (2-1) S: Gene Garber (3) | Third | 2 out |
| Thursday, April 28 |
| » Lost to Royals (11-9), 6-3 | Yankee Stadium (7-4) | 14-7 | Lost 2 |
| » W: Floyd Bannister (3-1) L: Rick Rhoden (1-3) S: Dan Quisenberry (1) | Second | 2 out |
| Friday, April 29 |
| » Defeated Rangers (8-12), 2-1 | Yankee Stadium (8-4) | 15-7 | |
| » W: John Candelaria (2-2) L: Charlie Hough (3-3) | Third | 1½ out |
| Saturday, April 30 |
| » Defeated Rangers (8-13), 15-3 | Yankee Stadium (9-4) | 16-7 | Won 2 |
| » W: Richard Dotson (3-0) L: Bobby Witt (0-4) | Third | ½ out |
| Sunday, May 1 |
| » Lost to Rangers (9-13), 5-1 | Yankee Stadium (9-5) | 16-8 | |
| » W: Paul Kilgus (3-2) L: Al Leiter (3-1) S: Dale Mohorcic (1) | Second | ½ out |
| Monday, May 2 |
| » Defeated White Sox (12-11), 6-4 | Comiskey Park I (1-0) | 17-8 | |
| » W: Tim Stoddard (2-1) L: Bobby Thigpen (0-2) S: John Candelaria (1) | Second | ½ out |
| Tuesday, May 3 |
| » Defeated White Sox (12-12), 4-1 | Comiskey Park I (2-0) | 18-8 | Won 2 |
| » W: Charles Hudson (3-1) L: Dave LaPoint (3-2) S: Cecilio Guante (2) | First | -- |
| Wednesday, May 4 |
| » Defeated Royals (14-12), 4-3 | Royals Stadium (1-0) | 19-8 | Won 3 |
| » W: John Candelaria (3-2) L: Ted Power (1-1) S: Tim Stoddard (1) | First | -- |
| Thursday, May 5 |
| » Defeated Royals (14-13), 5-3 | Royals Stadium (2-0) | 20-8 | Won 4 |
| » W: Richard Dotson (4-0) L: Mark Gubicza (3-3) S: Cecilio Guante (3) | First | -- |
| Friday, May 6 |
| » Lost to Rangers (11-16), 7-6 | Arlington Stadium (0-1) | 20-9 | |
| » W: Paul Kilgus (4-2) L: Al Leiter (3-2) S: Jose Cecena (1) | First | -- |
| Saturday, May 7 |
| » Lost to Rangers (12-16), 3-2 | Arlington Stadium (0-2) | 20-10 | Lost 2 |
| » W: Dale Mohorcic (1-0) L: Cecilio Guante (2-1) | First | -- |
| Sunday, May 8 |
| » Lost to Rangers (13-16), 10-8 | Arlington Stadium (0-3) | 20-11 | Lost 3 |
| » W: Jeff Russell (1-0) L: Steve Shields (0-1) S: Dale Mohorcic (3) | First | -- |
| Tuesday, May 10 |
| » Defeated White Sox (15-15), 17-3 | Yankee Stadium (10-5) | 21-11 | |
| » W: John Candelaria (4-2) L: Ricky Horton (3-5) | First | -- |
| Wednesday, May 11 |
| » Defeated White Sox (15-16), 12-2 | Yankee Stadium (11-5) | 22-11 | Won 2 |
| » W: Richard Dotson (5-0) L: Jack McDowell (2-3) | First | -- |
| Friday, May 13 |
| » Lost to Angels (14-21), 5-4 | Yankee Stadium (11-6) | 22-12 | |
| » W: Willie Fraser (4-2) L: Cecilio Guante (2-2) S: De Wayne Buice (3) | First | -- |
| Saturday, May 14 |
| » Defeated Angels (14-22), 6-2 | Yankee Stadium (12-6) | 23-12 | |
| » W: Tommy John (2-0) L: Dan Petry (2-3) S: Dave Righetti (5) | First | -- |
| Sunday, May 15 |
| » Defeated Angels (14-23), 9-2 | Yankee Stadium (13-6) | 24-12 | Won 2 |
| » W: Charles Hudson (4-1) L: Chuck Finley (2-6) | First | -- |
| Monday, May 16 |
| » Defeated Mariners (16-23), 3-1 | Yankee Stadium (14-6) | 25-12 | Won 3 |
| » W: John Candelaria (5-2) L: Mike Moore (2-5) S: Dave Righetti (6) | First | -- |
| Tuesday, May 17 |
| » Lost to Mariners (17-23), 6-2 | Yankee Stadium (14-7) | 25-13 | |
| » W: Bill Swift (3-1) L: Richard Dotson (5-1) | First | -- |
| » Major-league debuts: Bob Geren (Yankees) |
| Friday, May 20 |
| » Lost to Athletics (29-11), 11-3 | Yankee Stadium (14-8) | 25-14 | Lost 2 |
| » W: Bob Welch (7-2) L: Tommy John (2-1) | First | -- |
| Saturday, May 21 |
| » Defeated Athletics (29-12), 3-2 | Yankee Stadium (15-8) | 26-14 | |
| » W: Rick Rhoden (2-3) L: Curt Young (3-2) S: Dave Righetti (7) | First | -- |
| Sunday, May 22 |
| » Defeated Athletics (29-13), 2-0 | Yankee Stadium (16-8) | 27-14 | Won 2 |
| » W: John Candelaria (6-2) L: Storm Davis (4-2) | First | -- |
| Monday, May 23 |
| » Defeated Angels (17-27), 5-2 | Anaheim Stadium (1-0) | 28-14 | Won 3 |
| » W: Cecilio Guante (3-2) L: Mike Witt (1-6) S: Dave Righetti (8) | First | -- |
| Tuesday, May 24 |
| » Defeated Angels (17-28), 5-3 | Anaheim Stadium (2-0) | 29-14 | Won 4 |
| » W: Al Leiter (4-2) L: Kirk McCaskill (2-4) S: Dave Righetti (9) | First | -- |
| Wednesday, May 25 |
| » Defeated Angels (17-29), 4-2 | Anaheim Stadium (3-0) | 30-14 | Won 5 |
| » W: Neil Allen (1-0) L: De Wayne Buice (1-3) | First | -- |
| Friday, May 27 |
| » Defeated Mariners (20-27), 5-1 | Kingdome (1-0) | 31-14 | Won 6 |
| » W: Tommy John (3-1) L: Scott Bankhead (0-2) S: Cecilio Guante (4) | First | -- |
| Saturday, May 28 |
| » Lost to Mariners (21-27), 6-1 | Kingdome (1-1) | 31-15 | |
| » W: Bill Swift (5-1) L: Rick Rhoden (2-4) | First | -- |
| Sunday, May 29 |
| » Defeated Mariners (21-28), 7-3 | Kingdome (2-1) | 32-15 | |
| » W: John Candelaria (7-2) L: Mike Campbell (3-6) S: Cecilio Guante (5) | First | -- |
| Monday, May 30 |
| » Lost to Athletics (35-14), 3-2 | Oakland-Alameda County Stadium (0-1) | 32-16 | |
| » W: Dennis Eckersley (1-1) L: Steve Shields (0-2) | First | -- |
| Tuesday, May 31 |
| » Defeated Athletics (35-15), 5-0 | Oakland-Alameda County Stadium (1-1) | 33-16 | |
| » W: Neil Allen (2-0) L: Steve Ontiveros (3-2) | First | -- |
| Wednesday, June 1 |
| » Lost to Athletics (36-15), 4-3 | Oakland-Alameda County Stadium (1-2) | 33-17 | |
| » W: Gene Nelson (4-2) L: Charles Hudson (4-2) S: Dennis Eckersley (17) | First | -- |
| Friday, June 3 |
| » Defeated Orioles (11-41), 4-0 | Memorial Stadium (1-0) | 34-17 | |
| » W: Tommy John (4-1) L: Jose Bautista (2-4) | First | -- |
| Saturday, June 4 |
| » Lost to Orioles (12-41), 7-6 | Memorial Stadium (1-1) | 34-18 | |
| » W: Doug Sisk (2-2) L: Hipolito Pena (0-1) | First | -- |
| Sunday, June 5 |
| » Defeated Orioles (12-42), 9-2 | Memorial Stadium (2-1) | 35-18 | |
| » W: Richard Dotson (6-1) L: Jay Tibbs (2-3) | First | -- |
| Monday, June 6 |
| » Lost to Red Sox (26-26), 3-2 | Yankee Stadium (16-9) | 35-19 | |
| » W: Bruce Hurst (7-3) L: Neil Allen (2-1) S: Lee Smith (7) | First | -- |
| Tuesday, June 7 |
| » Defeated Red Sox (26-27), 4-3 | Yankee Stadium (17-9) | 36-19 | |
| » W: Charles Hudson (5-2) L: Oil Can Boyd (5-5) S: Cecilio Guante (6) | First | -- |
| Wednesday, June 8 |
| » Lost to Red Sox (27-27), 4-3 | Yankee Stadium (17-10) | 36-20 | |
| » W: Roger Clemens (9-3) L: Tommy John (4-2) S: Lee Smith (8) | First | -- |
| Friday, June 10 |
| » Lost to Orioles (15-43), 5-3 | Yankee Stadium (17-11) | 36-21 | Lost 2 |
| » W: Mike Boddicker (3-8) L: Rick Rhoden (2-5) | First | -- |
| Saturday, June 11 |
| » Defeated Orioles (15-44), 8-6 | Yankee Stadium (18-11) | 37-21 | |
| » W: John Candelaria (8-2) L: Jeff Ballard (2-3) S: Dave Righetti (10) | First | -- |
| Sunday, June 12 |
| » Defeated Orioles (15-45), 6-5 | Yankee Stadium (19-11) | 38-21 | Won 2 |
| » W: Cecilio Guante (4-2) L: Tom Niedenfuer (0-1) | First | -- |
| Monday, June 13 |
| » Defeated Red Sox (28-30), 12-6 | Fenway Park (1-0) | 39-21 | Won 3 |
| » W: Richard Dotson (7-1) L: Roger Clemens (9-4) S: Cecilio Guante (7) | First | -- |
| Tuesday, June 14 |
| » Lost to Red Sox (29-30), 7-3 | Fenway Park (1-1) | 39-22 | |
| » W: Mike Smithson (2-2) L: Neil Allen (2-2) S: Lee Smith (9) | First | -- |
| Wednesday, June 15 |
| » Lost to Red Sox (30-30), 8-3 | Fenway Park (1-2) | 39-23 | Lost 2 |
| » W: Bruce Hurst (8-3) L: Al Leiter (4-3) | First | -- |
| Friday, June 17 |
| » Lost to Indians (38-27), 6-4 | Cleveland Stadium (0-1) | 39-24 | Lost 3 |
| » W: John Farrell (7-4) L: John Candelaria (8-3) S: Doug Jones (16) | First | -- |
| Saturday, June 18 |
| » Defeated Indians (38-28), 6-3 | Cleveland Stadium (1-1) | 40-24 | |
| » W: Rick Rhoden (3-5) L: Scott Bailes (6-6) S: Cecilio Guante (8) | First | -- |
| Sunday, June 19 |
| » Lost to Indians (39-28), 11-3 | Cleveland Stadium (1-2) | 40-25 | |
| » W: Tom Candiotti (7-6) L: Richard Dotson (7-2) | First | -- |
| Monday, June 20 |
| » Lost to Tigers (41-26), 2-1 | Tiger Stadium (0-1) | 40-26 | Lost 2 |
| » W: Willie Hernandez (5-2) L: Cecilio Guante (4-3) | Second | ½ out |
| Tuesday, June 21 |
| » Lost to Tigers (42-26), 7-6 | Tiger Stadium (0-2) | 40-27 | Lost 3 |
| » W: Eric King (1-0) L: Cecilio Guante (4-4) | Second | 1½ out |
| Wednesday, June 22 |
| » Lost to Tigers (43-26), 3-2 | Tiger Stadium (0-3) | 40-28 | Lost 4 |
| » W: Mike Henneman (2-2) L: Charles Hudson (5-3) | Second | 2½ out |
| Thursday, June 23 |
| » Defeated Indians (40-31), 4-3 | Yankee Stadium (20-11) | 41-28 | |
| » Manager: Lou Piniella |
| » W: Dave Righetti (2-0) L: Jon Perlman (0-1) | Second | 2 out |
| Friday, June 24 |
| » Lost to Indians (41-31), 7-5 | Yankee Stadium (20-12) | 41-29 | |
| » W: Brad Havens (1-0) L: Richard Dotson (7-3) S: Doug Jones (18) | Second | 2 out |
| Saturday, June 25 |
| » Defeated Indians (41-32), 4-1 | Yankee Stadium (21-12) | 42-29 | |
| » W: Tommy John (5-2) L: Greg Swindell (10-6) S: Cecilio Guante (9) | Second | 2 out |
| Sunday, June 26 |
| » Defeated Indians (41-33), 4-3 | Yankee Stadium (22-12) | 43-29 | Won 2 |
| » W: Dave Righetti (3-0) L: Bud Black (3-2) | Second | 1 out |
| Monday, June 27 |
| » Lost to Tigers (45-28), 6-3 | Yankee Stadium (22-13) | 43-30 | |
| » W: Jack Morris (7-8) L: John Candelaria (8-4) S: Mike Henneman (14) | Second | 2 out |
| Tuesday, June 28 |
| » Lost to Tigers (46-28), 6-1 | Yankee Stadium (22-14) | 43-31 | Lost 2 |
| » W: Frank Tanana (10-4) L: Rick Rhoden (3-6) | Second | 3 out |
| Wednesday, June 29 |
| » Defeated Tigers (46-29), 7-3 | Yankee Stadium (23-14) | 44-31 | |
| » W: Steve Shields (1-2) L: Walt Terrell (3-5) | Second | 2 out |
| Thursday, June 30 |
| » Defeated White Sox (34-42), 5-3 | Comiskey Park I (3-0) | 45-31 | Won 2 |
| » W: Tommy John (6-2) L: Dave LaPoint (6-8) S: Dave Righetti (11) | Second | 1½ out |
| Friday, July 1 |
| » Lost to White Sox (35-42), 2-1 | Comiskey Park I (3-1) | 45-32 | |
| » W: Bobby Thigpen (5-5) L: Steve Shields (1-3) | Second | 2½ out |
| Saturday, July 2 |
| » Defeated White Sox (35-43), 4-0 | Comiskey Park I (4-1) | 46-32 | |
| » W: John Candelaria (9-4) L: Jerry Reuss (6-5) | Second | 2½ out |
| Sunday, July 3 |
| » Lost to White Sox (36-43), 4-3 | Comiskey Park I (4-2) | 46-33 | |
| » W: Jeff Bittiger (1-2) L: Cecilio Guante (4-5) | Second | 2½ out |
| Monday, July 4 |
| » Defeated Rangers (38-42), 13-2 | Arlington Stadium (1-3) | 47-33 | |
| » W: Charles Hudson (6-3) L: Charlie Hough (8-8) | Second | 2½ out |
| Tuesday, July 5 |
| » Defeated Rangers (38-43), 5-3 | Arlington Stadium (2-3) | 48-33 | Won 2 |
| » W: Tommy John (7-2) L: Ray Hayward (4-6) S: Tim Stoddard (2) | Second | 1½ out |
| Wednesday, July 6 |
| » Lost to Rangers (39-43), 4-2 | Arlington Stadium (2-4) | 48-34 | |
| » W: Jeff Russell (8-2) L: Ron Guidry (0-1) S: Mitch Williams (12) | Second | 2½ out |
| Friday, July 8 |
| » Lost to Royals (45-40), 4-0 | Yankee Stadium (23-15) | 48-35 | Lost 2 |
| » W: Mark Gubicza (12-5) L: John Candelaria (9-5) | Second | 3 out |
| Saturday, July 9 |
| » Defeated Royals (45-41), 5-3 | Yankee Stadium (24-15) | 49-35 | |
| » W: Rick Rhoden (4-6) L: Ted Power (4-3) S: Charles Hudson (2) | Second | 3 out |
| Sunday, July 10 |
| » Lost to Royals (46-41), 5-3 | Yankee Stadium (24-16) | 49-36 | |
| » W: Rick Anderson (1-0) L: Tim Stoddard (2-2) S: Steve Farr (9) | Second | 3 out |
| Former Yankee Ernie Nevel dies in Springfield, MO at the age of 70. |
| Thursday, July 14 |
| » Defeated White Sox (41-47), 7-5 | Yankee Stadium (25-16) | 50-36 | |
| » W: John Candelaria (10-5) L: Jerry Reuss (6-6) S: Cecilio Guante (10) | Second | 2 out |
| Former Yankee Whitey Witt dies in Salem Co., NJ at the age of 93. |
| Friday, July 15 |
| » Defeated White Sox (41-48), 5-3 | Yankee Stadium (26-16) | 51-36 | Won 2 |
| » W: Rick Rhoden (5-6) L: Jack McDowell (4-7) S: Cecilio Guante (11) | Second | 1 out |
| Saturday, July 16 |
| » Lost to White Sox (42-48), 7-4 | Yankee Stadium (26-17) | 51-37 | |
| » W: Melido Perez (9-5) L: Tommy John (7-3) S: Bobby Thigpen (19) | Second | 2 out |
| Sunday, July 17 |
| » Defeated White Sox (42-49), 7-3 | Yankee Stadium (27-17) | 52-37 | |
| » W: Ron Guidry (1-1) L: Dave LaPoint (7-10) S: Tim Stoddard (3) | Second | 1 out |
| Monday, July 18 |
| » Defeated Rangers (41-50), 7-2 | Yankee Stadium (28-17) | 53-37 | Won 2 |
| » W: Richard Dotson (8-3) L: Paul Kilgus (7-9) | Second | 1 out |
| Tuesday, July 19 |
| » Lost to Rangers (42-50), 7-2 | Yankee Stadium (28-18) | 53-38 | |
| » W: Charlie Hough (9-10) L: John Candelaria (10-6) | Second | 1 out |
| Thursday, July 21 |
| » Lost to Royals (48-47), 6-5 | Royals Stadium (2-1) | 53-39 | Lost 2 |
| » W: Steve Farr (3-2) L: Cecilio Guante (4-6) | Second | 2 out |
| Friday, July 22 |
| » Defeated Royals (48-48), 9-8 | Royals Stadium (3-1) | 54-39 | |
| » W: Neil Allen (3-2) L: Israel Sanchez (0-1) S: Dave Righetti (12) | Second | 1 out |
| Saturday, July 23 |
| » Lost to Royals (49-48), 6-5 | Royals Stadium (3-2) | 54-40 | |
| » W: Rick Anderson (2-0) L: Dave Righetti (3-1) S: Steve Farr (10) | Second | 1 out |
| Sunday, July 24 |
| » Defeated Royals (49-49), 10-8 | Royals Stadium (4-2) | 55-40 | |
| » W: Neil Allen (4-2) L: Bret Saberhagen (10-10) S: Dave Righetti (13) | First | -- |
| Monday, July 25 |
| » Defeated Brewers (51-48), 3-2 | Yankee Stadium (29-18) | 56-40 | Won 2 |
| » W: John Candelaria (11-6) L: Teddy Higuera (7-6) | First | -- |
| Tuesday, July 26 |
| » Defeated Brewers (51-49), 3-2 | Yankee Stadium (30-18) | 57-40 | Won 3 |
| » W: Rick Rhoden (6-6) L: Don August (5-4) S: Dave Righetti (14) | First | -- |
| Wednesday, July 27 |
| » Defeated Brewers (51-50), 16-3 | Yankee Stadium (31-18) | 58-40 | Won 4 |
| » W: Tommy John (8-3) L: Chris Bosio (6-12) | First | -- |
| Thursday, July 28 |
| » Lost to Brewers (52-50), 6-1 | Yankee Stadium (31-19) | 58-41 | |
| » W: Mike Birkbeck (5-5) L: Ron Guidry (1-2) S: Chuck Crim (6) | Second | ½ out |
| Friday, July 29 |
| » Lost to Blue Jays (51-52), 7-1 | Exhibition Stadium (3-2) | 58-42 | Lost 2 |
| » W: Jeff Musselman (3-0) L: Richard Dotson (8-4) | Second | 1 out |
| » Major-league debuts: Hal Morris (Yankees) |
| Saturday, July 30 |
| » Defeated Blue Jays (51-53), 3-1 | Exhibition Stadium (4-2) | 59-42 | |
| » W: John Candelaria (12-6) L: Mike Flanagan (10-7) S: Dave Righetti (15) | Second | 1 out |
| Sunday, July 31 |
| » Defeated Blue Jays (51-54), 6-3 | Exhibition Stadium (5-2) | 60-42 | Won 2 |
| » W: Rick Rhoden (7-6) L: Jimmy Key (6-2) S: Dave Righetti (16) | Second | 1 out |
| Tuesday, August 2 |
| » Lost to Brewers (53-54), 11-5 | County Stadium (1-3) | 60-43 | |
| » W: Mike Birkbeck (6-5) L: Tommy John (8-4) | Third | 1½ out |
| Wednesday, August 3 |
| » Lost to Brewers (54-54), 6-5 | County Stadium (1-4) | 60-44 | Lost 2 |
| » W: Chuck Crim (4-5) L: Dave Righetti (3-2) S: Dan Plesac (26) | Second | 1½ out |
| » Major-league debuts: Dave Eiland (Yankees) |
| Friday, August 5 |
| » Lost to Twins (60-47), 7-5 | Yankee Stadium (31-20) | 60-45 | Lost 3 |
| » W: Freddie Toliver (3-1) L: Rick Rhoden (7-7) S: Jeff Reardon (28) | Third | 4 out |
| » Lost to Twins (61-47), 11-2 | Yankee Stadium (31-21) | 60-46 | Lost 4 |
| » W: Frank Viola (17-4) L: Lee Guetterman (0-1) | Third | 4 out |
| Saturday, August 6 |
| » Defeated Twins (61-48), 5-3 | Yankee Stadium (32-21) | 61-46 | |
| » W: Steve Shields (2-3) L: Mark Portugal (1-2) S: Dave Righetti (17) | Second | 4 out |
| Sunday, August 7 |
| » Defeated Twins (61-49), 5-1 | Yankee Stadium (33-21) | 62-46 | Won 2 |
| » W: Richard Dotson (9-4) L: Charlie Lea (6-6) | Second | 3 out |
| Monday, August 8 |
| » Major-league debuts: Rick Reed (Pirates) |
| Tuesday, August 9 |
| » Lost to Blue Jays (56-58), 6-3 | Yankee Stadium (33-22) | 62-47 | |
| » W: Mike Flanagan (11-8) L: John Candelaria (12-7) S: Duane Ward (8) | Third | 3½ out |
| Wednesday, August 10 |
| » Lost to Blue Jays (57-58), 5-0 | Yankee Stadium (33-23) | 62-48 | Lost 2 |
| » W: Jimmy Key (7-2) L: Rick Rhoden (7-8) S: Tom Henke (22) | Third | 4½ out |
| Thursday, August 11 |
| » Lost to Blue Jays (58-58), 6-5 | Yankee Stadium (33-24) | 62-49 | Lost 3 |
| » W: Duane Ward (8-1) L: Dave Righetti (3-3) | Third | 5 out |
| Friday, August 12 |
| » Defeated Twins (64-50), 6-4 | Hubert H. Humphrey Metrodome (4-0) | 63-49 | |
| » W: Steve Shields (3-3) L: Jeff Reardon (0-4) S: Dave Righetti (18) | Third | 4 out |
| Saturday, August 13 |
| » Lost to Twins (65-50), 12-2 | Hubert H. Humphrey Metrodome (4-1) | 63-50 | |
| » W: Roy Smith (1-0) L: Richard Dotson (9-5) | Third | 4 out |
| Sunday, August 14 |
| » Defeated Twins (65-51), 9-6 | Hubert H. Humphrey Metrodome (5-1) | 64-50 | |
| » W: John Candelaria (13-7) L: Freddie Toliver (4-2) | Third | 4 out |
| Tuesday, August 16 |
| » Lost to Angels (60-59), 15-6 | Yankee Stadium (33-25) | 64-51 | |
| » W: Willie Fraser (9-10) L: Rick Rhoden (7-9) | Third | 3½ out |
| Wednesday, August 17 |
| » Defeated Angels (60-60), 11-7 | Yankee Stadium (34-25) | 65-51 | |
| » W: Scott Nielsen (1-0) L: Stew Cliburn (4-2) S: Dave Righetti (19) | Third | 2½ out |
| Thursday, August 18 |
| » Lost to Angels (61-60), 7-1 | Yankee Stadium (34-26) | 65-52 | |
| » W: Chuck Finley (7-11) L: Tommy John (8-5) S: Greg Minton (7) | Third | 3½ out |
| Friday, August 19 |
| » Defeated Mariners (47-75), 5-3 | Yankee Stadium (35-26) | 66-52 | |
| » W: Dave Righetti (4-3) L: Mike Schooler (4-5) | Third | 4 out |
| » Lost to Mariners (48-75), 6-1 | Yankee Stadium (35-27) | 66-53 | |
| » W: Mike Moore (7-13) L: Richard Dotson (9-6) | Third | 4 out |
| Saturday, August 20 |
| » Lost to Mariners (49-75), 9-5 | Yankee Stadium (35-28) | 66-54 | Lost 2 |
| » W: Mike Campbell (4-8) L: Scott Nielsen (1-1) | Third | 5 out |
| Sunday, August 21 |
| » Lost to Mariners (50-75), 4-2 | Yankee Stadium (35-29) | 66-55 | Lost 3 |
| » W: Scott Bankhead (7-7) L: Rick Rhoden (7-10) S: Mike Schooler (9) | Third | 6 out |
| Monday, August 22 |
| » Lost to Athletics (79-47), 9-2 | Yankee Stadium (35-30) | 66-56 | Lost 4 |
| » W: Curt Young (8-7) L: Charles Hudson (6-4) | Third | 6 out |
| Tuesday, August 23 |
| » Defeated Athletics (79-48), 5-4 | Yankee Stadium (36-30) | 67-56 | |
| » W: Dave Righetti (5-3) L: Greg Cadaret (4-2) | Third | 5 out |
| Wednesday, August 24 |
| » Defeated Athletics (79-49), 7-6 | Yankee Stadium (37-30) | 68-56 | Won 2 |
| » W: Cecilio Guante (5-6) L: Gene Nelson (7-5) | Third | 4 out |
| Thursday, August 25 |
| » Lost to Brewers (65-65), 4-1 | County Stadium (1-5) | 68-57 | |
| » W: Teddy Higuera (11-8) L: Richard Dotson (9-7) | Third | 4½ out |
| Friday, August 26 |
| » Lost to Angels (64-64), 7-6 | Anaheim Stadium (3-1) | 68-58 | Lost 2 |
| » W: Bryan Harvey (5-4) L: Steve Shields (3-4) | Third | 5½ out |
| Saturday, August 27 |
| » Lost to Angels (65-64), 12-0 | Anaheim Stadium (3-2) | 68-59 | Lost 3 |
| » W: Terry Clark (6-2) L: Charles Hudson (6-5) | Third | 5½ out |
| Sunday, August 28 |
| » Lost to Angels (66-64), 13-2 | Anaheim Stadium (3-3) | 68-60 | Lost 4 |
| » W: Chuck Finley (8-12) L: Tommy John (8-6) | Third | 5½ out |
| Monday, August 29 |
| » Lost to Mariners (53-79), 9-6 | Kingdome (2-2) | 68-61 | Lost 5 |
| » W: Mark Langston (10-10) L: Scott Nielsen (1-2) | Third | 5½ out |
| Tuesday, August 30 |
| » Lost to Mariners (54-79), 7-1 | Kingdome (2-3) | 68-62 | Lost 6 |
| » W: Mike Campbell (5-8) L: Richard Dotson (9-8) | Third | 5½ out |
| Wednesday, August 31 |
| » Defeated Mariners (54-80), 4-1 | Kingdome (3-3) | 69-62 | |
| » W: Rick Rhoden (8-10) L: Scott Bankhead (7-9) | Third | 5½ out |
| Friday, September 2 |
| » Defeated Athletics (84-51), 4-1 | Oakland-Alameda County Stadium (2-2) | 70-62 | Won 2 |
| » W: Tommy John (9-6) L: Curt Young (8-8) S: Dave Righetti (20) | Third | 4 out |
| » Major-league debuts: Felix Jose (Athletics) |
| Saturday, September 3 |
| » Lost to Athletics (85-51), 5-4 | Oakland-Alameda County Stadium (2-3) | 70-63 | |
| » W: Eric Plunk (6-2) L: Dale Mohorcic (2-7) S: Dennis Eckersley (37) | Third | 4 out |
| Sunday, September 4 |
| » Lost to Athletics (86-51), 11-2 | Oakland-Alameda County Stadium (2-4) | 70-64 | Lost 2 |
| » W: Dave Stewart (17-11) L: Richard Dotson (9-9) | Second | 4 out |
| » Major-league debuts: Lance Blankenship (Athletics) |
| Monday, September 5 |
| » Defeated Indians (66-71), 7-2 | Yankee Stadium (38-30) | 71-64 | |
| » W: Rick Rhoden (9-10) L: Don Gordon (2-3) | Third | 4 out |
| Tuesday, September 6 |
| » Lost to Indians (67-71), 1-0 | Yankee Stadium (38-31) | 71-65 | |
| » W: Greg Swindell (15-13) L: Al Leiter (4-4) | Fourth | 5 out |
| Wednesday, September 7 |
| » Lost to Indians (68-71), 5-4 | Yankee Stadium (38-32) | 71-66 | Lost 2 |
| » W: Rod Nichols (1-4) L: Tommy John (9-7) S: Doug Jones (31) | Fourth | 5 out |
| Thursday, September 8 |
| » Defeated Tigers (76-64), 7-4 | Yankee Stadium (39-32) | 72-66 | |
| » W: Hipolito Pena (1-1) L: Mike Henneman (8-5) | Third | 4½ out |
| Friday, September 9 |
| » Defeated Tigers (76-65), 3-2 | Yankee Stadium (40-32) | 73-66 | Won 2 |
| » W: Dale Mohorcic (3-7) L: Walt Terrell (7-13) | Third | 4½ out |
| Saturday, September 10 |
| » Defeated Tigers (76-66), 9-4 | Yankee Stadium (41-32) | 74-66 | Won 3 |
| » W: Rick Rhoden (10-10) L: Jack Morris (12-13) | Third | 4½ out |
| » Major-league debuts: Torey Lovullo (Tigers) |
| Sunday, September 11 |
| » Defeated Tigers (76-67), 5-4 | Yankee Stadium (42-32) | 75-66 | Won 4 |
| » W: Steve Shields (4-4) L: Willie Hernandez (5-5) | Second | 3½ out |
| Monday, September 12 |
| » Lost to Indians (70-73), 8-6 | Cleveland Stadium (1-3) | 75-67 | |
| » W: Greg Swindell (16-13) L: Tommy John (9-8) S: Doug Jones (33) | Third | 4½ out |
| Tuesday, September 13 |
| » Defeated Indians (70-74), 5-4 | Cleveland Stadium (2-3) | 76-67 | |
| » W: Neil Allen (5-2) L: Scott Bailes (8-13) S: Dave Righetti (21) | Third | 4½ out |
| Wednesday, September 14 |
| » Defeated Indians (70-75), 7-5 | Cleveland Stadium (3-3) | 77-67 | Won 2 |
| » W: Richard Dotson (10-9) L: Rich Yett (8-6) S: Dale Mohorcic (6) | Second | 4½ out |
| Thursday, September 15 |
| » Defeated Red Sox (82-64), 5-3 | Fenway Park (2-2) | 78-67 | Won 3 |
| » W: Rick Rhoden (11-10) L: Roger Clemens (16-11) S: Dave Righetti (22) | Second | 3½ out |
| Friday, September 16 |
| » Lost to Red Sox (83-64), 7-4 | Fenway Park (2-3) | 78-68 | |
| » W: Wes Gardner (8-4) L: Steve Shields (4-5) S: Lee Smith (27) | Second | 4½ out |
| » Major-league debuts: Carlos Quintana (Red Sox) |
| Saturday, September 17 |
| » Lost to Red Sox (84-64), 3-1 | Fenway Park (2-4) | 78-69 | Lost 2 |
| » W: Bruce Hurst (18-5) L: Charles Hudson (6-6) | Third | 5½ out |
|