| Tuesday, February 23 |
| Former Red Sox Pete Donohue dies in Ft.Worth, TX at the age of 88. |
| Friday, February 26 |
| Former Red Sox Tom Oliver dies in Montgomery, AL at the age of 86. |
| Wednesday, March 16 |
| Former Red Sox Jigger Statz dies in Corona Del Mar, CA at the age of 91. |
| Monday, April 4 |
| » Lost to Tigers (1-0), 5-3 | Fenway Park (0-1) | 0-1 | |
| » W: Jack Morris (1-0) L: Lee Smith (0-1) S: Mike Henneman (1) | Third | 1 out |
| » Major-league debuts: Brady Anderson (Red Sox) |
| Wednesday, April 6 |
| » Defeated Tigers (1-1), 6-5 | Fenway Park (1-1) | 1-1 | |
| » W: Dennis Lamp (1-0) L: Willie Hernandez (0-1) S: Lee Smith (1) | Second | 1 out |
| Thursday, April 7 |
| » Lost to Tigers (2-1), 11-6 | Fenway Park (1-2) | 1-2 | |
| » W: Frank Tanana (1-0) L: Steve Ellsworth (0-1) | Third | 1½ out |
| » Major-league debuts: Steve Ellsworth (Red Sox) Don Heinkel (Tigers) |
| Friday, April 8 |
| » Defeated Rangers (1-3), 4-0 | Arlington Stadium (1-0) | 2-2 | |
| » W: Oil Can Boyd (1-0) L: Mike Jeffcoat (0-1) | Fourth | 1½ out |
| Saturday, April 9 |
| » Defeated Rangers (1-4), 2-1 | Arlington Stadium (2-0) | 3-2 | Won 2 |
| » W: Roger Clemens (1-0) L: Charlie Hough (1-1) S: Lee Smith (2) | Third | 1½ out |
| Sunday, April 10 |
| » Lost to Rangers (2-4), 4-1 | Arlington Stadium (2-1) | 3-3 | |
| » W: Paul Kilgus (1-0) L: Jeff Sellers (0-1) S: Mitch Williams (2) | Third | 2½ out |
| Tuesday, April 12 |
| » Defeated Brewers (2-4), 3-1 | Fenway Park (2-2) | 4-3 | |
| » W: Bruce Hurst (1-0) L: Chris Bosio (1-1) S: Lee Smith (3) | Third | 2 out |
| Wednesday, April 13 |
| » Defeated Brewers (2-5), 6-3 | Fenway Park (3-2) | 5-3 | Won 2 |
| » W: Oil Can Boyd (2-0) L: Juan Nieves (0-2) S: Lee Smith (4) | Third | 2 out |
| Thursday, April 14 |
| » Defeated Brewers (2-6), 2-0 | Fenway Park (4-2) | 6-3 | Won 3 |
| » W: Roger Clemens (2-0) L: Bill Wegman (0-2) | Third | 2 out |
| Friday, April 15 |
| » Lost to Rangers (4-5), 3-2 | Fenway Park (4-3) | 6-4 | |
| » W: Charlie Hough (2-1) L: Wes Gardner (0-1) | Third | 3 out |
| Saturday, April 16 |
| » Lost to Rangers (5-5), 2-0 | Fenway Park (4-4) | 6-5 | Lost 2 |
| » W: Paul Kilgus (2-0) L: Steve Ellsworth (0-2) S: Mitch Williams (4) | Fourth | 3½ out |
| Sunday, April 17 |
| » Defeated Rangers (5-6), 15-2 | Fenway Park (5-4) | 7-5 | |
| » W: Bruce Hurst (2-0) L: Mike Jeffcoat (0-2) | Fourth | 3½ out |
| Monday, April 18 |
| » Defeated Rangers (5-7), 4-3 | Fenway Park (6-4) | 8-5 | Won 2 |
| » W: Lee Smith (1-1) L: Mitch Williams (0-1) | Fourth | 3 out |
| Tuesday, April 19 |
| » Defeated Tigers (7-5), 7-3 | Tiger Stadium (1-0) | 9-5 | Won 3 |
| » W: Roger Clemens (3-0) L: Jack Morris (2-2) | Second | 2 out |
| Thursday, April 21 |
| » Defeated Tigers (7-6), 12-3 | Tiger Stadium (2-0) | 10-5 | Won 4 |
| » W: Steve Ellsworth (1-2) L: Jeff Robinson (1-2) | Second | 2 out |
| Sunday, April 24 |
| » Defeated Brewers (7-8), 4-0 | County Stadium (1-0) | 11-5 | Won 5 |
| » W: Roger Clemens (4-0) L: Teddy Higuera (2-1) | Third | 2 out |
| Monday, April 25 |
| » Defeated Brewers (7-9), 5-1 | County Stadium (2-0) | 12-5 | Won 6 |
| » W: Bruce Hurst (3-0) L: Bill Wegman (1-3) | Third | 1½ out |
| Wednesday, April 27 |
| Former Red Sox Tommy Thomas dies in Dallastown, PA at the age of 89. |
| Thursday, April 28 |
| » Lost to White Sox (10-9), 6-0 | Comiskey Park I (0-1) | 12-6 | |
| » W: Dave LaPoint (3-1) L: Oil Can Boyd (2-1) | Third | 2½ out |
| Friday, April 29 |
| » Defeated Twins (8-12), 6-5 | Fenway Park (7-4) | 13-6 | |
| » W: Lee Smith (2-1) L: Juan Berenguer (3-3) | Second | 2 out |
| Saturday, April 30 |
| » Defeated Twins (8-13), 8-3 | Fenway Park (8-4) | 14-6 | Won 2 |
| » W: Bruce Hurst (4-0) L: Charlie Lea (0-3) S: Wes Gardner (1) | Second | 1 out |
| Sunday, May 1 |
| » Lost to Twins (9-13), 2-0 | Fenway Park (8-5) | 14-7 | |
| » W: Frank Viola (3-1) L: Jeff Sellers (0-2) | Third | 1 out |
| Monday, May 2 |
| » Lost to Royals (13-11), 2-0 | Fenway Park (8-6) | 14-8 | Lost 2 |
| » W: Floyd Bannister (4-1) L: Steve Ellsworth (1-3) S: Gene Garber (4) | Third | 2 out |
| Tuesday, May 3 |
| » Lost to Royals (14-11), 9-3 | Fenway Park (8-7) | 14-9 | Lost 3 |
| » W: Bret Saberhagen (4-2) L: Oil Can Boyd (2-2) | Third | 2½ out |
| Wednesday, May 4 |
| » Lost to White Sox (13-12), 6-2 | Fenway Park (8-8) | 14-10 | Lost 4 |
| » W: Jack McDowell (2-2) L: Roger Clemens (4-1) | Fourth | 3½ out |
| Thursday, May 5 |
| » Defeated White Sox (13-13), 16-3 | Fenway Park (9-8) | 15-10 | |
| » W: Bruce Hurst (5-0) L: Ricky Horton (3-4) | Fourth | 3½ out |
| Friday, May 6 |
| » Lost to Twins (10-16), 5-0 | Hubert H. Humphrey Metrodome (0-1) | 15-11 | |
| » W: Frank Viola (4-1) L: Jeff Sellers (0-3) | Third | 3½ out |
| Saturday, May 7 |
| » Lost to Twins (11-16), 5-2 | Hubert H. Humphrey Metrodome (0-2) | 15-12 | Lost 2 |
| » W: Bert Blyleven (2-3) L: Steve Ellsworth (1-4) | Fourth | 3½ out |
| Sunday, May 8 |
| » Defeated Twins (11-17), 10-6 | Hubert H. Humphrey Metrodome (1-2) | 16-12 | |
| » W: Oil Can Boyd (3-2) L: Mike Mason (0-1) | Fifth | 2½ out |
| Monday, May 9 |
| » Defeated Royals (14-17), 2-0 | Royals Stadium (1-0) | 17-12 | Won 2 |
| » W: Roger Clemens (5-1) L: Mark Gubicza (3-4) | Fourth | 2 out |
| Tuesday, May 10 |
| » Lost to Royals (15-17), 7-2 | Royals Stadium (1-1) | 17-13 | |
| » W: Floyd Bannister (5-2) L: Bruce Hurst (5-1) | Fifth | 3 out |
| Friday, May 13 |
| » Defeated Mariners (15-21), 14-8 | Fenway Park (10-8) | 18-13 | |
| » W: Oil Can Boyd (4-2) L: Mike Campbell (2-5) S: Wes Gardner (2) | Fourth | 2½ out |
| Saturday, May 14 |
| » Defeated Mariners (15-22), 3-0 | Fenway Park (11-8) | 19-13 | Won 2 |
| » W: Roger Clemens (6-1) L: Scott Bankhead (0-1) | Fourth | 2½ out |
| Sunday, May 15 |
| » Lost to Mariners (16-22), 11-7 | Fenway Park (11-9) | 19-14 | |
| » W: Mike Jackson (1-1) L: Lee Smith (2-2) | Fourth | 3½ out |
| Monday, May 16 |
| » Lost to Athletics (27-10), 3-0 | Fenway Park (11-10) | 19-15 | Lost 2 |
| » W: Storm Davis (4-1) L: Jeff Sellers (0-4) S: Dennis Eckersley (14) | Fourth | 4½ out |
| Tuesday, May 17 |
| » Lost to Athletics (28-10), 12-7 | Fenway Park (11-11) | 19-16 | Lost 3 |
| » W: Steve Ontiveros (2-1) L: Steve Ellsworth (1-5) S: Rick Honeycutt (4) | Fourth | 4½ out |
| Wednesday, May 18 |
| » Defeated Athletics (28-11), 4-1 | Fenway Park (12-11) | 20-16 | |
| » W: Oil Can Boyd (5-2) L: Dave Stewart (8-2) S: Lee Smith (5) | Fourth | 4 out |
| Friday, May 20 |
| » Lost to Angels (17-24), 4-2 | Fenway Park (12-12) | 20-17 | |
| » W: De Wayne Buice (1-2) L: Roger Clemens (6-2) S: Bryan Harvey (2) | Fourth | 4 out |
| Saturday, May 21 |
| » Defeated Angels (17-25), 8-4 | Fenway Park (13-12) | 21-17 | |
| » W: Bruce Hurst (6-1) L: Ray Krawczyk (0-1) S: Lee Smith (6) | Fourth | 4 out |
| Sunday, May 22 |
| » Defeated Angels (17-26), 12-4 | Fenway Park (14-12) | 22-17 | Won 2 |
| » W: Bob Stanley (1-0) L: Willie Fraser (4-3) | Fourth | 4 out |
| Monday, May 23 |
| » Lost to Mariners (19-25), 14-3 | Kingdome (0-1) | 22-18 | |
| » W: Bill Swift (4-1) L: Oil Can Boyd (5-3) | Fourth | 5 out |
| Tuesday, May 24 |
| » Lost to Mariners (20-25), 14-1 | Kingdome (0-2) | 22-19 | Lost 2 |
| » W: Mike Campbell (3-5) L: Mike Smithson (0-1) | Fourth | 6 out |
| Wednesday, May 25 |
| » Defeated Mariners (20-26), 4-0 | Kingdome (1-2) | 23-19 | |
| » W: Roger Clemens (7-2) L: Mark Langston (4-4) | Fourth | 6 out |
| Friday, May 27 |
| » Lost to Athletics (32-14), 3-2 | Oakland-Alameda County Stadium (0-1) | 23-20 | |
| » W: Curt Young (4-2) L: Bruce Hurst (6-2) S: Dennis Eckersley (15) | Fourth | 7 out |
| Saturday, May 28 |
| » Lost to Athletics (33-14), 7-5 | Oakland-Alameda County Stadium (0-2) | 23-21 | Lost 2 |
| » W: Rick Honeycutt (1-0) L: Dennis Lamp (1-1) S: Dennis Eckersley (16) | Fourth | 7 out |
| Sunday, May 29 |
| » Lost to Athletics (34-14), 5-4 | Oakland-Alameda County Stadium (0-3) | 23-22 | Lost 3 |
| » W: Gene Nelson (3-2) L: Jeff Sellers (0-5) S: Eric Plunk (2) | Fifth | 8 out |
| Monday, May 30 |
| » Defeated Angels (19-31), 5-2 | Anaheim Stadium (1-0) | 24-22 | |
| » W: Roger Clemens (8-2) L: Dan Petry (2-4) | Fifth | 7 out |
| Tuesday, May 31 |
| » Defeated Angels (19-32), 4-3 | Anaheim Stadium (2-0) | 25-22 | Won 2 |
| » W: Mike Smithson (1-1) L: Willie Fraser (4-4) | Fourth | 7 out |
| Thursday, June 2 |
| » Lost to Blue Jays (24-29), 5-4 | Fenway Park (14-13) | 25-23 | |
| » W: David Wells (3-2) L: Bruce Hurst (6-3) S: Mark Eichhorn (1) | Fourth | 7 out |
| Friday, June 3 |
| » Lost to Blue Jays (25-29), 6-3 | Fenway Park (14-14) | 25-24 | Lost 2 |
| » W: Todd Stottlemyre (2-7) L: Oil Can Boyd (5-4) S: Tom Henke (10) | Fifth | 8 out |
| Saturday, June 4 |
| » Lost to Blue Jays (26-29), 10-2 | Fenway Park (14-15) | 25-25 | Lost 3 |
| » W: Jim Clancy (3-6) L: Roger Clemens (8-3) S: Duane Ward (4) | Fifth | 8 out |
| Sunday, June 5 |
| » Lost to Blue Jays (27-29), 12-4 | Fenway Park (14-16) | 25-26 | Lost 4 |
| » W: Duane Ward (2-0) L: Mike Smithson (1-2) | Fifth | 9 out |
| Monday, June 6 |
| » Defeated Yankees (35-19), 3-2 | Yankee Stadium (1-0) | 26-26 | |
| » W: Bruce Hurst (7-3) L: Neil Allen (2-1) S: Lee Smith (7) | Fifth | 8 out |
| Tuesday, June 7 |
| » Lost to Yankees (36-19), 4-3 | Yankee Stadium (1-1) | 26-27 | |
| » W: Charles Hudson (5-2) L: Oil Can Boyd (5-5) S: Cecilio Guante (6) | Fifth | 9 out |
| Wednesday, June 8 |
| » Defeated Yankees (36-20), 4-3 | Yankee Stadium (2-1) | 27-27 | |
| » W: Roger Clemens (9-3) L: Tommy John (4-2) S: Lee Smith (8) | Fifth | 8 out |
| Friday, June 10 |
| » Lost to Blue Jays (28-32), 3-0 | Exhibition Stadium (0-1) | 27-28 | |
| » W: Dave Stieb (8-3) L: Jeff Sellers (0-6) S: Tom Henke (11) | Fifth | 8 out |
| Saturday, June 11 |
| » Lost to Blue Jays (29-32), 4-3 | Exhibition Stadium (0-2) | 27-29 | Lost 2 |
| » W: Duane Ward (3-0) L: Dennis Lamp (1-2) | Fifth | 9 out |
| Sunday, June 12 |
| » Defeated Blue Jays (29-33), 8-2 | Exhibition Stadium (1-2) | 28-29 | |
| » W: Oil Can Boyd (6-5) L: John Cerutti (3-3) | Fifth | 9 out |
| Monday, June 13 |
| » Lost to Yankees (39-21), 12-6 | Fenway Park (14-17) | 28-30 | |
| » W: Richard Dotson (7-1) L: Roger Clemens (9-4) S: Cecilio Guante (7) | Fifth | 10 out |
| Tuesday, June 14 |
| » Defeated Yankees (39-22), 7-3 | Fenway Park (15-17) | 29-30 | |
| » W: Mike Smithson (2-2) L: Neil Allen (2-2) S: Lee Smith (9) | Fifth | 9 out |
| Wednesday, June 15 |
| » Defeated Yankees (39-23), 8-3 | Fenway Park (16-17) | 30-30 | Won 2 |
| » W: Bruce Hurst (8-3) L: Al Leiter (4-3) | Fifth | 8 out |
| Thursday, June 16 |
| » Lost to Orioles (17-47), 8-4 | Memorial Stadium (0-1) | 30-31 | |
| » W: Jeff Ballard (3-3) L: John Trautwein (0-1) S: Mark Williamson (1) | Fifth | 8½ out |
| Friday, June 17 |
| » Lost to Orioles (18-47), 3-2 | Memorial Stadium (0-2) | 30-32 | Lost 2 |
| » W: Dave Schmidt (3-2) L: Dennis Lamp (1-3) | Fifth | 8½ out |
| Saturday, June 18 |
| » Defeated Orioles (18-48), 5-0 | Memorial Stadium (1-2) | 31-32 | |
| » W: Roger Clemens (10-4) L: Jose Bautista (2-6) | Fifth | 8½ out |
| Sunday, June 19 |
| » Defeated Orioles (18-49), 15-7 | Memorial Stadium (2-2) | 32-32 | Won 2 |
| » W: Wes Gardner (1-1) L: Dickie Noles (0-2) | Fifth | 7½ out |
| Monday, June 20 |
| » Defeated Indians (39-29), 14-7 | Cleveland Stadium (1-0) | 33-32 | Won 3 |
| » W: Bruce Hurst (9-3) L: Greg Swindell (10-5) | Fifth | 7 out |
| Tuesday, June 21 |
| » Defeated Indians (39-30), 10-6 | Cleveland Stadium (2-0) | 34-32 | Won 4 |
| » W: Bob Stanley (2-0) L: Rick Rodriguez (0-1) S: Lee Smith (10) | Fourth | 7 out |
| Wednesday, June 22 |
| » Lost to Indians (40-30), 3-1 | Cleveland Stadium (2-1) | 34-33 | |
| » W: John Farrell (8-4) L: Oil Can Boyd (6-6) S: Doug Jones (17) | Fifth | 8 out |
| Friday, June 24 |
| » Lost to Orioles (20-52), 6-2 | Fenway Park (16-18) | 34-34 | Lost 2 |
| » W: Jose Bautista (3-6) L: Roger Clemens (10-5) | Fifth | 8 out |
| Saturday, June 25 |
| » Defeated Orioles (20-53), 10-3 | Fenway Park (17-18) | 35-34 | |
| » W: Bob Stanley (3-0) L: Mark Williamson (1-5) | Fifth | 8 out |
| Sunday, June 26 |
| » Defeated Orioles (20-54), 10-1 | Fenway Park (18-18) | 36-34 | Won 2 |
| » W: Mike Smithson (3-2) L: Oswaldo Peraza (1-3) | Fourth | 7 out |
| Monday, June 27 |
| » Defeated Indians (41-34), 9-5 | Fenway Park (19-18) | 37-34 | Won 3 |
| » W: Dennis Lamp (2-3) L: John Farrell (8-5) | Fourth | 7 out |
| Tuesday, June 28 |
| » Defeated Indians (41-35), 6-1 | Fenway Park (20-18) | 38-34 | Won 4 |
| » W: Wes Gardner (2-1) L: Scott Bailes (6-7) | Fourth | 7 out |
| Wednesday, June 29 |
| » Defeated Indians (41-36), 5-1 | Fenway Park (21-18) | 39-34 | Won 5 |
| » W: Roger Clemens (11-5) L: Tom Candiotti (7-7) S: Lee Smith (11) | Third | 6 out |
| Friday, July 1 |
| » Lost to Royals (41-37), 8-7 | Royals Stadium (1-2) | 39-35 | |
| » W: Jeff Montgomery (1-1) L: Steve Ellsworth (1-6) S: Steve Farr (6) | Third | 7 out |
| Saturday, July 2 |
| » Lost to Royals (42-37), 3-1 | Royals Stadium (1-3) | 39-36 | Lost 2 |
| » W: Charlie Leibrandt (4-10) L: Oil Can Boyd (6-7) S: Steve Farr (7) | Fourth | 8 out |
| Sunday, July 3 |
| » Lost to Royals (43-37), 3-2 | Royals Stadium (1-4) | 39-37 | Lost 3 |
| » W: Jeff Montgomery (2-1) L: Lee Smith (2-3) S: Steve Farr (8) | Fourth | 8 out |
| Monday, July 4 |
| » Defeated Royals (43-38), 9-2 | Royals Stadium (2-4) | 40-37 | |
| » W: Roger Clemens (12-5) L: Ted Power (4-2) | Fourth | 8 out |
| Tuesday, July 5 |
| » Lost to Twins (46-34), 6-4 | Hubert H. Humphrey Metrodome (1-3) | 40-38 | |
| » W: Juan Berenguer (8-3) L: Lee Smith (2-4) S: Jeff Reardon (23) | Fourth | 8 out |
| Wednesday, July 6 |
| » Lost to Twins (47-34), 8-1 | Hubert H. Humphrey Metrodome (1-4) | 40-39 | Lost 2 |
| » W: Frank Viola (14-2) L: Bruce Hurst (9-4) | Fourth | 9 out |
| Thursday, July 7 |
| » Defeated Twins (47-35), 4-3 | Hubert H. Humphrey Metrodome (2-4) | 41-39 | |
| » W: Oil Can Boyd (7-7) L: Charlie Lea (5-4) S: Bob Stanley (1) | Fourth | 9 out |
| Friday, July 8 |
| » Lost to White Sox (39-44), 6-5 | Comiskey Park I (0-2) | 41-40 | |
| » W: John Davis (2-2) L: Mike Smithson (3-3) S: Bobby Thigpen (16) | Fourth | 8½ out |
| » Defeated White Sox (39-45), 10-7 | Comiskey Park I (1-2) | 42-40 | |
| » W: Dennis Lamp (3-3) L: Bill Long (3-4) | Fourth | 8½ out |
| Saturday, July 9 |
| » Lost to White Sox (40-45), 8-7 | Comiskey Park I (1-3) | 42-41 | |
| » W: Melido Perez (8-5) L: Tom Bolton (0-1) S: Bobby Thigpen (17) | Fourth | 9 out |
| » Defeated White Sox (40-46), 8-2 | Comiskey Park I (2-3) | 43-41 | |
| » W: Lee Smith (3-4) L: Ricky Horton (4-7) | Fourth | 9 out |
| » Major-league debuts: Ken Patterson (White Sox) |
| Sunday, July 10 |
| » Lost to White Sox (41-46), 4-1 | Comiskey Park I (2-4) | 43-42 | |
| » W: Dave LaPoint (7-9) L: Steve Curry (0-1) S: Bobby Thigpen (18) | Fifth | 9 out |
| Friday, July 15 |
| » Defeated Royals (46-42), 3-1 | Fenway Park (22-18) | 44-42 | |
| » Manager: Joe Morgan |
| » W: Roger Clemens (13-5) L: Bret Saberhagen (10-8) | Fourth | 7 out |
| » Defeated Royals (46-43), 7-4 | Fenway Park (23-18) | 45-42 | Won 2 |
| » W: Mike Smithson (4-3) L: Charlie Leibrandt (5-11) S: Lee Smith (12) | Fourth | 7 out |
| Saturday, July 16 |
| » Defeated Royals (46-44), 7-6 | Fenway Park (24-18) | 46-42 | Won 3 |
| » W: Lee Smith (4-4) L: Steve Farr (2-2) | Third | 7 out |
| Sunday, July 17 |
| » Defeated Royals (46-45), 10-8 | Fenway Park (25-18) | 47-42 | Won 4 |
| » W: Wes Gardner (3-1) L: Ted Power (4-4) | Third | 6 out |
| Monday, July 18 |
| » Defeated Twins (51-40), 6-5 | Fenway Park (26-18) | 48-42 | Won 5 |
| » W: Dennis Lamp (4-3) L: Bert Blyleven (7-9) S: Lee Smith (13) | Third | 6 out |
| Tuesday, July 19 |
| » Defeated Twins (51-41), 5-0 | Fenway Park (27-18) | 49-42 | Won 6 |
| » W: Mike Smithson (5-3) L: Allan Anderson (6-7) | Third | 5 out |
| Wednesday, July 20 |
| » Defeated Twins (51-42), 9-7 | Fenway Park (28-18) | 50-42 | Won 7 |
| » W: Tom Bolton (1-1) L: Keith Atherton (5-5) | Third | 5 out |
| Thursday, July 21 |
| » Defeated White Sox (43-51), 6-1 | Fenway Park (29-18) | 51-42 | Won 8 |
| » W: Oil Can Boyd (8-7) L: Jack McDowell (4-8) S: Bob Stanley (2) | Third | 4½ out |
| Friday, July 22 |
| » Defeated White Sox (43-52), 4-3 | Fenway Park (30-18) | 52-42 | Won 9 |
| » W: Wes Gardner (4-1) L: John Davis (2-3) S: Lee Smith (14) | Third | 3½ out |
| Saturday, July 23 |
| » Defeated White Sox (43-53), 11-5 | Fenway Park (31-18) | 53-42 | Won 10 |
| » W: Mike Smithson (6-3) L: Dave LaPoint (7-11) | Third | 2½ out |
| Sunday, July 24 |
| » Defeated White Sox (43-54), 3-2 | Fenway Park (32-18) | 54-42 | Won 11 |
| » W: Bruce Hurst (10-4) L: Bill Long (4-5) S: Lee Smith (15) | Second | 1½ out |
| Monday, July 25 |
| » Defeated Rangers (44-53), 2-0 | Arlington Stadium (3-1) | 55-42 | Won 12 |
| » W: Roger Clemens (14-5) L: Charlie Hough (9-11) | Third | 1½ out |
| Tuesday, July 26 |
| » Lost to Rangers (45-53), 9-8 | Arlington Stadium (3-2) | 55-43 | |
| » W: Craig McMurtry (2-0) L: Tom Bolton (1-2) S: Mitch Williams (14) | Third | 2½ out |
| Wednesday, July 27 |
| » Defeated Rangers (45-54), 10-7 | Arlington Stadium (4-2) | 56-43 | |
| » W: Bob Stanley (4-0) L: Mitch Williams (1-4) S: Lee Smith (16) | Third | 2½ out |
| Friday, July 29 |
| » Defeated Brewers (52-51), 6-4 | Fenway Park (33-18) | 57-43 | Won 2 |
| » W: Bruce Hurst (11-4) L: Bill Wegman (10-8) S: Lee Smith (17) | Third | 1½ out |
| » Defeated Brewers (52-52), 5-4 | Fenway Park (34-18) | 58-43 | Won 3 |
| » W: Dennis Lamp (5-3) L: Chris Bosio (6-13) S: Bob Stanley (3) | Third | 1½ out |
| Saturday, July 30 |
| » Defeated Brewers (52-53), 3-2 | Fenway Park (35-18) | 59-43 | Won 4 |
| » W: Roger Clemens (15-5) L: Teddy Higuera (7-7) | Third | 1½ out |
| Sunday, July 31 |
| » Defeated Brewers (52-54), 5-0 | Fenway Park (36-18) | 60-43 | Won 5 |
| » W: Mike Boddicker (7-12) L: Don August (5-5) | Third | 1½ out |
| Tuesday, August 2 |
| » Defeated Rangers (46-58), 7-2 | Fenway Park (37-18) | 61-43 | Won 6 |
| » W: Wes Gardner (5-1) L: Jeff Russell (8-4) | Second | 1 out |
| Wednesday, August 3 |
| » Defeated Rangers (46-59), 5-4 | Fenway Park (38-18) | 62-43 | Won 7 |
| » W: Dennis Lamp (6-3) L: Bobby Witt (3-7) S: Lee Smith (18) | First | -- |
| Thursday, August 4 |
| » Lost to Tigers (63-43), 11-6 | Tiger Stadium (2-1) | 62-44 | |
| » W: Walt Terrell (6-8) L: Roger Clemens (15-6) | Second | 1 out |
| Friday, August 5 |
| » Lost to Tigers (64-43), 3-1 | Tiger Stadium (2-2) | 62-45 | Lost 2 |
| » W: Jack Morris (9-11) L: Bob Stanley (4-1) S: Mike Henneman (17) | Second | 3 out |
| » Lost to Tigers (65-43), 3-2 | Tiger Stadium (2-3) | 62-46 | Lost 3 |
| » W: Eric King (2-1) L: Mike Boddicker (7-13) S: Mike Henneman (18) | Second | 3 out |
| Saturday, August 6 |
| » Lost to Tigers (66-43), 4-2 | Tiger Stadium (2-4) | 62-47 | Lost 4 |
| » W: Doyle Alexander (11-6) L: Wes Gardner (5-2) | Third | 4 out |
| Sunday, August 7 |
| » Defeated Tigers (66-44), 3-0 | Tiger Stadium (3-4) | 63-47 | |
| » W: Bruce Hurst (12-4) L: Jeff Robinson (13-5) | Third | 3 out |
| Monday, August 8 |
| » Major-league debuts: Rick Reed (Pirates) |
| Tuesday, August 9 |
| » Lost to Brewers (57-56), 3-2 | County Stadium (2-1) | 63-48 | |
| » W: Chuck Crim (5-5) L: Roger Clemens (15-7) | Second | 3 out |
| » Defeated Brewers (57-57), 5-1 | County Stadium (3-1) | 64-48 | |
| » W: Mike Boddicker (8-13) L: Bill Wegman (10-9) S: Bob Stanley (4) | Second | 3 out |
| Wednesday, August 10 |
| » Lost to Brewers (58-57), 8-3 | County Stadium (3-2) | 64-49 | |
| » W: Teddy Higuera (8-8) L: Mike Smithson (6-4) | Second | 4 out |
| Thursday, August 11 |
| » Lost to Brewers (59-57), 4-0 | County Stadium (3-3) | 64-50 | Lost 2 |
| » W: Don August (7-5) L: Wes Gardner (5-3) | Second | 4½ out |
| Friday, August 12 |
| » Defeated Tigers (68-46), 9-4 | Fenway Park (39-18) | 65-50 | |
| » W: Bruce Hurst (13-4) L: Doyle Alexander (11-7) S: Bob Stanley (5) | Second | 3½ out |
| Saturday, August 13 |
| » Defeated Tigers (68-47), 16-4 | Fenway Park (40-18) | 66-50 | Won 2 |
| » W: Mike Boddicker (9-13) L: Jeff Robinson (13-6) S: Tom Bolton (1) | Second | 2½ out |
| Former Red Sox Mel Almada dies in Caborca, Mexico at the age of 76. |
| Sunday, August 14 |
| » Lost to Tigers (69-47), 18-6 | Fenway Park (40-19) | 66-51 | |
| » W: Eric King (3-1) L: Roger Clemens (15-8) | Second | 3½ out |
| Tuesday, August 16 |
| » Lost to Mariners (46-73), 7-0 | Fenway Park (40-20) | 66-52 | Lost 2 |
| » W: Scott Bankhead (6-7) L: Wes Gardner (5-4) | Second | 3 out |
| Wednesday, August 17 |
| » Defeated Mariners (46-74), 7-2 | Fenway Park (41-20) | 67-52 | |
| » W: Bruce Hurst (14-4) L: Bill Swift (6-10) | Second | 2 out |
| Thursday, August 18 |
| » Lost to Mariners (47-74), 6-1 | Fenway Park (41-21) | 67-53 | |
| » W: Mark Langston (9-10) L: Mike Boddicker (9-14) | Second | 3 out |
| Friday, August 19 |
| » Defeated Athletics (77-46), 7-6 | Fenway Park (42-21) | 68-53 | |
| » W: Bob Stanley (5-1) L: Dave Stewart (15-11) | Second | 3 out |
| Saturday, August 20 |
| » Defeated Athletics (77-47), 7-5 | Fenway Park (43-21) | 69-53 | Won 2 |
| » W: Jeff Sellers (1-6) L: Todd Burns (5-1) S: Lee Smith (19) | Second | 3 out |
| Sunday, August 21 |
| » Lost to Athletics (78-47), 5-4 | Fenway Park (43-22) | 69-54 | |
| » W: Rick Honeycutt (3-2) L: Bob Stanley (5-2) S: Dennis Eckersley (35) | Second | 4 out |
| Monday, August 22 |
| » Defeated Angels (62-63), 6-2 | Fenway Park (44-22) | 70-54 | |
| » W: Bruce Hurst (15-4) L: Terry Clark (5-2) | Second | 3 out |
| Tuesday, August 23 |
| » Defeated Angels (62-64), 10-2 | Fenway Park (45-22) | 71-54 | Won 2 |
| » W: Mike Boddicker (10-14) L: Chuck Finley (7-12) | Second | 2 out |
| Wednesday, August 24 |
| » Lost to Angels (63-64), 4-3 | Fenway Park (45-23) | 71-55 | |
| » W: Mike Witt (10-12) L: Roger Clemens (15-9) S: Bryan Harvey (13) | Second | 2 out |
| Friday, August 26 |
| » Defeated Mariners (51-78), 5-3 | Kingdome (2-2) | 72-55 | |
| » W: Oil Can Boyd (9-7) L: Scott Bankhead (7-8) S: Lee Smith (20) | Second | 2 out |
| Saturday, August 27 |
| » Lost to Mariners (52-78), 8-6 | Kingdome (2-3) | 72-56 | |
| » W: Bill Wilkinson (2-2) L: Tom Bolton (1-3) S: Mike Schooler (10) | Second | 2 out |
| Sunday, August 28 |
| » Defeated Mariners (52-79), 7-2 | Kingdome (3-3) | 73-56 | |
| » W: Bruce Hurst (16-4) L: Mike Moore (7-14) | Second | 1 out |
| Monday, August 29 |
| » Lost to Athletics (82-50), 3-1 | Oakland-Alameda County Stadium (0-4) | 73-57 | |
| » W: Bob Welch (15-7) L: Mike Boddicker (10-15) S: Dennis Eckersley (36) | Second | 1 out |
| Tuesday, August 30 |
| » Lost to Athletics (83-50), 1-0 | Oakland-Alameda County Stadium (0-5) | 73-58 | Lost 2 |
| » W: Dave Stewart (16-11) L: Roger Clemens (15-10) | Second | 1 out |
| Wednesday, August 31 |
| » Lost to Athletics (84-50), 7-2 | Oakland-Alameda County Stadium (0-6) | 73-59 | Lost 3 |
| » W: Storm Davis (14-4) L: Mike Smithson (6-5) | Second | 2 out |
| Thursday, September 1 |
| » Defeated Angels (68-66), 4-2 | Anaheim Stadium (3-0) | 74-59 | |
| » W: Wes Gardner (6-4) L: Terry Clark (6-3) S: Lee Smith (21) | Second | 1 out |
| Friday, September 2 |
| » Lost to Angels (69-66), 3-2 | Anaheim Stadium (3-1) | 74-60 | |
| » W: Chuck Finley (9-12) L: Bruce Hurst (16-5) S: Bryan Harvey (14) | Second | 1 out |
| Former Red Sox Jim Bagby Jr. dies in Marietta, GA at the age of 72. |
| Saturday, September 3 |
| » Lost to Angels (70-66), 2-1 | Anaheim Stadium (3-2) | 74-61 | Lost 2 |
| » W: Mike Witt (12-12) L: Dennis Lamp (6-4) | Second | 1 out |
| » Major-league debuts: Mike Rochford (Red Sox) |
| Sunday, September 4 |
| » Defeated Angels (70-67), 6-5 | Anaheim Stadium (4-2) | 75-61 | |
| » W: Bob Stanley (6-2) L: Bryan Harvey (6-5) S: Lee Smith (22) | First | -- |
| Monday, September 5 |
| » Defeated Orioles (48-88), 4-1 | Memorial Stadium (3-2) | 76-61 | Won 2 |
| » W: Mike Smithson (7-5) L: Dave Schmidt (7-4) S: Lee Smith (23) | First | -- |
| Tuesday, September 6 |
| » Defeated Orioles (48-89), 6-1 | Memorial Stadium (4-2) | 77-61 | Won 3 |
| » W: Wes Gardner (7-4) L: Jay Tibbs (4-13) | First | -- |
| Wednesday, September 7 |
| » Lost to Orioles (49-89), 4-3 | Memorial Stadium (4-3) | 77-62 | |
| » W: Mark Thurmond (1-6) L: Bob Stanley (6-3) | First | -- |
| » Major-league debuts: Curt Schilling (Orioles) |
| Friday, September 9 |
| » Defeated Indians (68-72), 7-4 | Fenway Park (46-23) | 78-62 | |
| » W: Mike Boddicker (11-15) L: Rich Yett (8-5) S: Lee Smith (24) | First | -- |
| » Major-league debuts: Mike Walker (Indians) |
| Saturday, September 10 |
| » Defeated Indians (68-73), 6-0 | Fenway Park (47-23) | 79-62 | Won 2 |
| » W: Roger Clemens (16-10) L: Bud Black (4-4) | First | -- |
| » Major-league debuts: Tom Lampkin (Indians) |
| Sunday, September 11 |
| » Lost to Indians (69-73), 4-2 | Fenway Park (47-24) | 79-63 | |
| » W: Tom Candiotti (12-8) L: Bob Stanley (6-4) S: Doug Jones (32) | First | -- |
| Monday, September 12 |
| » Defeated Orioles (51-91), 6-1 | Fenway Park (48-24) | 80-63 | |
| » W: Bruce Hurst (17-5) L: Curt Schilling (0-1) | First | -- |
| Tuesday, September 13 |
| » Defeated Orioles (51-92), 6-4 | Fenway Park (49-24) | 81-63 | Won 2 |
| » W: Mike Smithson (8-5) L: Pete Harnisch (0-1) S: Lee Smith (25) | First | -- |
| » Major-league debuts: Pete Harnisch (Orioles) |
| Wednesday, September 14 |
| » Defeated Orioles (51-93), 4-3 | Fenway Park (50-24) | 82-63 | Won 3 |
| » W: Mike Boddicker (12-15) L: Jose Bautista (6-14) S: Lee Smith (26) | First | -- |
| Thursday, September 15 |
| » Lost to Yankees (78-67), 5-3 | Fenway Park (50-25) | 82-64 | |
| » W: Rick Rhoden (11-10) L: Roger Clemens (16-11) S: Dave Righetti (22) | First | -- |
| Friday, September 16 |
| » Defeated Yankees (78-68), 7-4 | Fenway Park (51-25) | 83-64 | |
| » W: Wes Gardner (8-4) L: Steve Shields (4-5) S: |