| Monday, April 6 |
| » Lost to Giants (1-0), 4-3 | Candlestick Park (0-1) | 0-1 | |
| » W: Jeff Robinson (1-0) L: Dave Dravecky (0-1) | Third | 1 out |
| » Major-league debuts: Joey Cora (Padres) |
| Tuesday, April 7 |
| » Lost to Giants (2-0), 4-3 | Candlestick Park (0-2) | 0-2 | Lost 2 |
| » W: Mike LaCoss (1-0) L: Ed Whitson (0-1) S: Jeff Robinson (1) | Third | 2 out |
| Wednesday, April 8 |
| » Lost to Giants (3-0), 2-1 | Candlestick Park (0-3) | 0-3 | Lost 3 |
| » W: Roger Mason (1-0) L: Andy Hawkins (0-1) S: Scott Garrelts (1) | Fourth | 3 out |
| Friday, April 10 |
| » Lost to Reds (3-0), 6-3 | Riverfront Stadium (0-1) | 0-4 | Lost 4 |
| » W: Rob Murphy (1-0) L: Dave Dravecky (0-2) S: John Franco (1) | Fifth | 4½ out |
| Saturday, April 11 |
| » Lost to Reds (4-0), 5-1 | Riverfront Stadium (0-2) | 0-5 | Lost 5 |
| » W: Tom Browning (1-0) L: Eric Show (0-1) | Sixth | 5 out |
| Sunday, April 12 |
| » Defeated Reds (4-1), 5-2 | Riverfront Stadium (1-2) | 1-5 | |
| » W: Ed Whitson (1-1) L: Guy Hoffman (0-1) S: Lance McCullers (1) | Fifth | 5 out |
| Monday, April 13 |
| » Lost to Giants (6-2), 13-6 | San Diego/Jack Murphy Stadium (0-1) | 1-6 | |
| » W: Jim Gott (1-0) L: Dave Dravecky (0-3) S: Jeff Robinson (2) | Sixth | 5 out |
| Tuesday, April 14 |
| » Lost to Giants (7-2), 3-2 | San Diego/Jack Murphy Stadium (0-2) | 1-7 | Lost 2 |
| » W: Mark Grant (1-0) L: Ed Wojna (0-1) S: Scott Garrelts (2) | Sixth | 5½ out |
| Wednesday, April 15 |
| » Lost to Giants (8-2), 1-0 | San Diego/Jack Murphy Stadium (0-3) | 1-8 | Lost 3 |
| » W: Kelly Downs (1-0) L: Storm Davis (0-1) | Sixth | 6½ out |
| Thursday, April 16 |
| » Defeated Dodgers (4-7), 3-2 | San Diego/Jack Murphy Stadium (1-3) | 2-8 | |
| » W: Lance McCullers (1-0) L: Matt Young (0-3) | Sixth | 6 out |
| Friday, April 17 |
| » Lost to Dodgers (5-7), 5-3 | San Diego/Jack Murphy Stadium (1-4) | 2-9 | |
| » W: Fernando Valenzuela (2-0) L: Ed Whitson (1-2) | Sixth | 6 out |
| Saturday, April 18 |
| » Lost to Dodgers (6-7), 5-2 | San Diego/Jack Murphy Stadium (1-5) | 2-10 | Lost 2 |
| » W: Ken Howell (1-0) L: Lance McCullers (1-1) | Sixth | 7 out |
| Sunday, April 19 |
| » Lost to Dodgers (7-7), 9-1 | San Diego/Jack Murphy Stadium (1-6) | 2-11 | Lost 3 |
| » W: Bob Welch (1-1) L: Ed Wojna (0-2) | Sixth | 8 out |
| Monday, April 20 |
| » Lost to Reds (10-3), 12-3 | San Diego/Jack Murphy Stadium (1-7) | 2-12 | Lost 4 |
| » W: Guy Hoffman (1-1) L: Storm Davis (0-2) | Sixth | 9 out |
| Tuesday, April 21 |
| » Defeated Reds (10-4), 3-2 | San Diego/Jack Murphy Stadium (2-7) | 3-12 | |
| » W: Lance McCullers (2-1) L: Rob Murphy (2-1) | Sixth | 8 out |
| Wednesday, April 22 |
| » Defeated Reds (10-5), 6-3 | San Diego/Jack Murphy Stadium (3-7) | 4-12 | Won 2 |
| » W: Ed Whitson (2-2) L: Bill Landrum (1-1) S: Craig Lefferts (1) | Fifth | 7 out |
| Thursday, April 23 |
| » Lost to Reds (11-5), 3-2 | San Diego/Jack Murphy Stadium (3-8) | 4-13 | |
| » W: Tom Browning (2-2) L: Andy Hawkins (0-2) S: Ron Robinson (2) | Fourth | 7½ out |
| Friday, April 24 |
| » Lost to Dodgers (10-8), 5-0 | Dodger Stadium (0-1) | 4-14 | Lost 2 |
| » W: Bob Welch (2-1) L: Ed Wojna (0-3) | Fifth | 8½ out |
| Saturday, April 25 |
| » Lost to Dodgers (11-8), 4-2 | Dodger Stadium (0-2) | 4-15 | Lost 3 |
| » W: Orel Hershiser (2-2) L: Storm Davis (0-3) | Sixth | 9½ out |
| Sunday, April 26 |
| » Defeated Dodgers (11-9), 4-0 | Dodger Stadium (1-2) | 5-15 | |
| » W: Eric Show (1-1) L: Rick Honeycutt (0-1) | Sixth | 9½ out |
| Tuesday, April 28 |
| » Defeated Cardinals (10-8), 5-2 | Busch Stadium II (1-0) | 6-15 | Won 2 |
| » W: Ed Whitson (3-2) L: Tim Conroy (0-1) S: Lance McCullers (2) | Sixth | 9 out |
| Wednesday, April 29 |
| » Lost to Cardinals (11-8), 10-6 | Busch Stadium II (1-1) | 6-16 | |
| » W: Pat Perry (1-0) L: Lance McCullers (2-2) | Sixth | 9 out |
| » Major-league debuts: Rod Booker (Cardinals) |
| Thursday, April 30 |
| » Lost to Cardinals (12-8), 5-4 | Busch Stadium II (1-2) | 6-17 | Lost 2 |
| » W: Greg Mathews (2-2) L: Storm Davis (0-4) S: Pat Perry (1) | Sixth | 10 out |
| Friday, May 1 |
| » Lost to Cubs (11-10), 7-5 | Wrigley Field (0-1) | 6-18 | Lost 3 |
| » W: Frank DiPino (1-0) L: Lance McCullers (2-3) S: Lee Smith (5) | Sixth | 10½ out |
| Saturday, May 2 |
| » Lost to Cubs (12-10), 7-3 | Wrigley Field (0-2) | 6-19 | Lost 4 |
| » W: Steve Trout (2-1) L: Ed Whitson (3-3) S: Ed Lynch (2) | Sixth | 10½ out |
| Sunday, May 3 |
| » Lost to Cubs (13-10), 4-2 | Wrigley Field (0-3) | 6-20 | Lost 5 |
| » W: Rick Sutcliffe (4-2) L: Andy Hawkins (0-3) S: Lee Smith (6) | Sixth | 11½ out |
| Monday, May 4 |
| » Defeated Pirates (10-12), 9-5 | San Diego/Jack Murphy Stadium (4-8) | 7-20 | |
| » W: Storm Davis (1-4) L: Bob Patterson (1-4) S: Lance McCullers (3) | Sixth | 11 out |
| Tuesday, May 5 |
| » Lost to Pirates (11-12), 10-8 | San Diego/Jack Murphy Stadium (4-9) | 7-21 | |
| » W: Bob Walk (1-0) L: Eric Show (1-2) S: Don Robinson (5) | Sixth | 12 out |
| Wednesday, May 6 |
| » Lost to Cardinals (14-11), 3-0 | San Diego/Jack Murphy Stadium (4-10) | 7-22 | Lost 2 |
| » W: Joe Magrane (2-0) L: Ed Whitson (3-4) | Sixth | 12 out |
| Thursday, May 7 |
| » Lost to Cardinals (15-11), 17-10 | San Diego/Jack Murphy Stadium (4-11) | 7-23 | Lost 3 |
| » W: Bob Forsch (3-1) L: Andy Hawkins (0-4) | Sixth | 12½ out |
| Friday, May 8 |
| » Lost to Cubs (16-12), 6-3 | San Diego/Jack Murphy Stadium (4-12) | 7-24 | Lost 4 |
| » W: Rick Sutcliffe (5-2) L: Storm Davis (1-5) S: Lee Smith (8) | Sixth | 13½ out |
| Saturday, May 9 |
| » Lost to Cubs (17-12), 5-2 | San Diego/Jack Murphy Stadium (4-13) | 7-25 | Lost 5 |
| » W: Greg Maddux (2-2) L: Eric Show (1-3) S: Lee Smith (9) | Sixth | 14½ out |
| Sunday, May 10 |
| » Defeated Cubs (17-13), 14-2 | San Diego/Jack Murphy Stadium (5-13) | 8-25 | |
| » W: Ed Whitson (4-4) L: Jamie Moyer (2-3) S: Greg Booker (1) | Sixth | 13½ out |
| Tuesday, May 12 |
| » Lost to Pirates (13-16), 12-5 | Three Rivers Stadium (0-1) | 8-26 | |
| » W: Rick Reuschel (2-2) L: Andy Hawkins (0-5) | Sixth | 13½ out |
| Wednesday, May 13 |
| » Lost to Pirates (14-16), 9-5 | Three Rivers Stadium (0-2) | 8-27 | Lost 2 |
| » W: Bob Walk (2-1) L: Craig Lefferts (0-1) S: Don Robinson (6) | Sixth | 14 out |
| Thursday, May 14 |
| » Lost to Pirates (15-16), 10-3 | Three Rivers Stadium (0-3) | 8-28 | Lost 3 |
| » W: Brian Fisher (1-1) L: Eric Show (1-4) S: John Smiley (1) | Sixth | 15 out |
| Friday, May 15 |
| » Lost to Phillies (13-20), 7-4 | Veteran's Stadium (0-1) | 8-29 | Lost 4 |
| » W: Shane Rawley (3-2) L: Ed Whitson (4-5) S: Steve Bedrosian (5) | Sixth | 15 out |
| Saturday, May 16 |
| » Lost to Phillies (14-20), 9-0 | Veteran's Stadium (0-2) | 8-30 | Lost 5 |
| » W: Don Carman (2-2) L: Jimmy Jones (0-1) | Fifth | 15 out |
| Sunday, May 17 |
| » Defeated Phillies (14-21), 6-5 | Veteran's Stadium (1-2) | 9-30 | |
| » W: Andy Hawkins (1-5) L: Michael Jackson (0-3) S: Lance McCullers (4) | Fifth | 14 out |
| Monday, May 18 |
| » Defeated Mets (16-20), 7-5 | Shea Stadium (1-0) | 10-30 | Won 2 |
| » W: Dave Dravecky (1-3) L: Ron Darling (2-2) S: Lance McCullers (5) | Sixth | 13½ out |
| Tuesday, May 19 |
| » Lost to Mets (17-20), 5-4 | Shea Stadium (1-1) | 10-31 | |
| » W: Roger McDowell (1-0) L: Eric Show (1-5) | Fifth | 14 out |
| Wednesday, May 20 |
| » Lost to Mets (18-20), 10-3 | Shea Stadium (1-2) | 10-32 | Lost 2 |
| » W: Rick Aguilera (4-2) L: Ed Whitson (4-6) | Fifth | 15 out |
| Friday, May 22 |
| » Defeated Expos (19-21), 5-3 | San Diego/Jack Murphy Stadium (6-13) | 11-32 | |
| » W: Andy Hawkins (2-5) L: Curt Brown (0-1) S: Rich Gossage (1) | Sixth | 15 out |
| Saturday, May 23 |
| » Lost to Expos (20-21), 6-0 | San Diego/Jack Murphy Stadium (6-14) | 11-33 | |
| » W: Neal Heaton (5-2) L: Dave Dravecky (1-4) | Sixth | 15 out |
| Sunday, May 24 |
| » Lost to Expos (21-21), 2-1 | San Diego/Jack Murphy Stadium (6-15) | 11-34 | Lost 2 |
| » W: Floyd Youmans (2-3) L: Eric Show (1-6) S: Tim Burke (4) | Fifth | 16 out |
| Monday, May 25 |
| » Lost to Phillies (18-23), 6-4 | San Diego/Jack Murphy Stadium (6-16) | 11-35 | Lost 3 |
| » W: Dan Schatzeder (3-1) L: Dave Dravecky (1-5) S: Steve Bedrosian (8) | Sixth | 16 out |
| » Major-league debuts: Shane Mack (Padres) |
| Tuesday, May 26 |
| » Lost to Phillies (19-23), 3-1 | San Diego/Jack Murphy Stadium (6-17) | 11-36 | Lost 4 |
| » W: Shane Rawley (5-2) L: Jimmy Jones (0-2) S: Steve Bedrosian (9) | Sixth | 16 out |
| Wednesday, May 27 |
| » Lost to Phillies (20-23), 6-4 | San Diego/Jack Murphy Stadium (6-18) | 11-37 | Lost 5 |
| » W: Don Carman (3-3) L: Andy Hawkins (2-6) S: Steve Bedrosian (10) | Fifth | 16 out |
| Friday, May 29 |
| » Lost to Mets (23-22), 5-4 | San Diego/Jack Murphy Stadium (6-19) | 11-38 | Lost 6 |
| » W: Terry Leach (3-0) L: Craig Lefferts (0-2) S: Roger McDowell (4) | Fifth | 16 out |
| Saturday, May 30 |
| » Lost to Mets (24-22), 3-0 | San Diego/Jack Murphy Stadium (6-20) | 11-39 | Lost 7 |
| » W: Sid Fernandez (6-2) L: Eric Show (1-7) | Sixth | 17 out |
| Sunday, May 31 |
| » Defeated Mets (24-23), 1-0 | San Diego/Jack Murphy Stadium (7-20) | 12-39 | |
| » W: Ed Whitson (5-6) L: John Mitchell (0-1) S: Rich Gossage (2) | Sixth | 17 out |
| Tuesday, June 2 |
| » Lost to Expos (26-23), 6-2 | Stade Olympique (0-1) | 12-40 | |
| » W: Bryn Smith (3-1) L: Jimmy Jones (0-3) | Fifth | 17½ out |
| Wednesday, June 3 |
| » Lost to Expos (27-23), 4-3 | Stade Olympique (0-2) | 12-41 | Lost 2 |
| » W: Neal Heaton (7-2) L: Andy Hawkins (2-7) S: Tim Burke (6) | Fifth | 18½ out |
| Thursday, June 4 |
| » Lost to Expos (28-23), 8-5 | Stade Olympique (0-3) | 12-42 | Lost 3 |
| » W: Floyd Youmans (4-3) L: Storm Davis (1-6) S: Randy St. Claire (6) | Sixth | 19 out |
| Friday, June 5 |
| » Defeated Braves (26-27), 10-3 | Atlanta-Fulton County Stadium (1-0) | 13-42 | |
| » W: Eric Show (2-7) L: Doyle Alexander (1-1) | Sixth | 19 out |
| Saturday, June 6 |
| » Defeated Braves (26-28), 5-3 | Atlanta-Fulton County Stadium (2-0) | 14-42 | Won 2 |
| » W: Ed Whitson (6-6) L: Larry McWilliams (0-1) S: Lance McCullers (6) | Sixth | 19 out |
| Sunday, June 7 |
| » Lost to Braves (27-28), 13-12 | Atlanta-Fulton County Stadium (2-1) | 14-43 | |
| » W: Gene Garber (8-3) L: Greg Booker (0-1) | Sixth | 19 out |
| Monday, June 8 |
| » Defeated Astros (27-28), 5-4 | Astrodome (1-0) | 15-43 | |
| » W: Craig Lefferts (1-2) L: Bob Knepper (2-7) S: Rich Gossage (3) | Fifth | 19 out |
| Tuesday, June 9 |
| » Lost to Astros (28-28), 1-0 | Astrodome (1-1) | 15-44 | |
| » W: Danny Darwin (3-4) L: Dave Dravecky (1-6) S: Dave Smith (11) | Sixth | 19 out |
| Wednesday, June 10 |
| » Lost to Astros (29-28), 10-1 | Astrodome (1-2) | 15-45 | Lost 2 |
| » W: Mike Scott (7-3) L: Storm Davis (1-7) | Fifth | 19 out |
| Thursday, June 11 |
| » Lost to Giants (33-26), 1-0 | Candlestick Park (0-4) | 15-46 | Lost 3 |
| » W: Kelly Downs (5-2) L: Eric Show (2-8) | Fifth | 19 out |
| Friday, June 12 |
| » Defeated Giants (33-27), 5-0 | Candlestick Park (1-4) | 16-46 | |
| » W: Ed Whitson (7-6) L: Mike LaCoss (6-3) | Fifth | 18 out |
| Saturday, June 13 |
| » Defeated Giants (33-28), 11-2 | Candlestick Park (2-4) | 17-46 | Won 2 |
| » W: Andy Hawkins (3-7) L: Atlee Hammaker (3-3) S: Craig Lefferts (2) | Sixth | 18 out |
| Sunday, June 14 |
| » Defeated Giants (33-29), 4-1 | Candlestick Park (3-4) | 18-46 | Won 3 |
| » W: Dave Dravecky (2-6) L: Mark Davis (4-5) | Sixth | 18 out |
| Tuesday, June 16 |
| » Defeated Dodgers (29-34), 3-2 | San Diego/Jack Murphy Stadium (8-20) | 19-46 | Won 4 |
| » W: Lance McCullers (3-3) L: Alejandro Pena (0-6) S: Rich Gossage (4) | Sixth | 16½ out |
| Wednesday, June 17 |
| » Defeated Dodgers (29-35), 8-7 | San Diego/Jack Murphy Stadium (9-20) | 20-46 | Won 5 |
| » W: Craig Lefferts (2-2) L: Brian Holton (2-1) S: Lance McCullers (7) | Sixth | 16½ out |
| Thursday, June 18 |
| » Defeated Giants (33-32), 3-1 | San Diego/Jack Murphy Stadium (10-20) | 21-46 | Won 6 |
| » W: Storm Davis (2-7) L: Atlee Hammaker (3-4) S: Rich Gossage (5) | Sixth | 16½ out |
| Friday, June 19 |
| » Lost to Giants (34-32), 7-6 | San Diego/Jack Murphy Stadium (10-21) | 21-47 | |
| » W: Jeff Robinson (4-5) L: Lance McCullers (3-4) S: Scott Garrelts (8) | Sixth | 16½ out |
| Saturday, June 20 |
| » Defeated Giants (34-33), 10-4 | San Diego/Jack Murphy Stadium (11-21) | 22-47 | |
| » W: Jimmy Jones (1-3) L: Jeff Robinson (4-6) S: Lance McCullers (8) | Fifth | 15½ out |
| Sunday, June 21 |
| » Lost to Giants (35-33), 11-2 | San Diego/Jack Murphy Stadium (11-22) | 22-48 | |
| » W: Kelly Downs (6-3) L: Eric Show (2-9) | Sixth | 16½ out |
| Tuesday, June 23 |
| » Defeated Astros (37-32), 4-1 | San Diego/Jack Murphy Stadium (12-22) | 23-48 | |
| » W: Ed Whitson (8-6) L: Nolan Ryan (4-7) | Sixth | 16½ out |
| Wednesday, June 24 |
| » Lost to Astros (38-32), 12-7 | San Diego/Jack Murphy Stadium (12-23) | 23-49 | |
| » W: Larry Andersen (5-3) L: Lance McCullers (3-5) | Sixth | 17½ out |
| Thursday, June 25 |
| » Defeated Astros (38-33), 4-1 | San Diego/Jack Murphy Stadium (13-23) | 24-49 | |
| » W: Dave Dravecky (3-6) L: Mike Scott (9-4) S: Lance McCullers (9) | Sixth | 16½ out |
| Friday, June 26 |
| » Defeated Braves (34-38), 5-1 | San Diego/Jack Murphy Stadium (14-23) | 25-49 | Won 2 |
| » W: Eric Show (3-9) L: Rick Mahler (4-8) S: Rich Gossage (6) | Sixth | 16½ out |
| Saturday, June 27 |
| » Defeated Braves (34-39), 8-4 | San Diego/Jack Murphy Stadium (15-23) | 26-49 | Won 3 |
| » W: Lance McCullers (4-5) L: Jeff Dedmon (2-2) | Fifth | 15½ out |
| Sunday, June 28 |
| » Lost to Braves (35-39), 5-2 | San Diego/Jack Murphy Stadium (15-24) | 26-50 | |
| » W: Charlie Puleo (2-1) L: Ed Whitson (8-7) S: Gene Garber (8) | Fifth | 15½ out |
| Monday, June 29 |
| » Defeated Dodgers (35-40), 3-0 | Dodger Stadium (2-2) | 27-50 | |
| » W: Jimmy Jones (2-3) L: Bob Welch (8-4) | Sixth | 15 out |
| Tuesday, June 30 |
| » Lost to Dodgers (36-40), 4-0 | Dodger Stadium (2-3) | 27-51 | |
| » W: Orel Hershiser (9-7) L: Dave Dravecky (3-7) | Fifth | 16 out |
| Wednesday, July 1 |
| » Defeated Dodgers (36-41), 4-0 | Dodger Stadium (3-3) | 28-51 | |
| » W: Eric Show (4-9) L: Rick Honeycutt (2-8) | Sixth | 16 out |
| Friday, July 3 |
| » Lost to Expos (41-36), 2-1 | Stade Olympique (0-4) | 28-52 | |
| » W: Floyd Youmans (5-3) L: Andy Hawkins (3-8) S: Jeff Parrett (3) | Sixth | 16½ out |
| Saturday, July 4 |
| » Lost to Expos (42-36), 4-3 | Stade Olympique (0-5) | 28-53 | Lost 2 |
| » W: Tim Burke (1-0) L: Rich Gossage (0-1) | Sixth | 17½ out |
| Sunday, July 5 |
| » Defeated Expos (42-37), 3-2 | Stade Olympique (1-5) | 29-53 | |
| » W: Rich Gossage (1-1) L: Jeff Parrett (1-3) | Fifth | 17½ out |
| Monday, July 6 |
| » Lost to Cubs (43-39), 7-0 | Wrigley Field (0-4) | 29-54 | |
| » W: Steve Trout (5-3) L: Mark Grant (1-3) | Fifth | 17½ out |
| Tuesday, July 7 |
| » Lost to Cubs (44-39), 7-5 | Wrigley Field (0-5) | 29-55 | Lost 2 |
| » W: Scott Sanderson (4-4) L: Eric Show (4-10) S: Lee Smith (22) | Fifth | 17½ out |
| Wednesday, July 8 |
| » Lost to Cubs (45-39), 12-8 | Wrigley Field (0-6) | 29-56 | Lost 3 |
| » W: Les Lancaster (2-0) L: Lance McCullers (4-6) | Sixth | 17½ out |
| Friday, July 10 |
| » Lost to Pirates (38-47), 6-5 | Three Rivers Stadium (0-4) | 29-57 | Lost 4 |
| » W: Don Robinson (6-5) L: Rich Gossage (1-2) | Sixth | 18 out |
| Saturday, July 11 |
| » Defeated Pirates (38-48), 3-1 | Three Rivers Stadium (1-4) | 30-57 | |
| » W: Mark Grant (2-3) L: Brian Fisher (4-6) S: Mark Davis (1) | Sixth | 17 out |
| Sunday, July 12 |
| » Lost to Pirates (39-48), 4-2 | Three Rivers Stadium (1-5) | 30-58 | |
| » W: Mike Dunne (4-4) L: Eric Show (4-11) S: Brett Gideon (1) | Sixth | 17 out |
| Thursday, July 16 |
| » Defeated Cardinals (56-31), 9-8 | San Diego/Jack Murphy Stadium (16-24) | 31-58 | |
| » W: Lance McCullers (5-6) L: Todd Worrell (4-4) | Sixth | 16 out |
| Friday, July 17 |
| » Lost to Cardinals (57-31), 4-3 | San Diego/Jack Murphy Stadium (16-25) | 31-59 | |
| » W: Greg Mathews (7-6) L: Mark Grant (2-4) S: Todd Worrell (19) | Sixth | 17 out |
| Saturday, July 18 |
| » Defeated Cardinals (57-32), 4-3 | San Diego/Jack Murphy Stadium (17-25) | 32-59 | |
| » W: Rich Gossage (2-2) L: Ken Dayley (2-1) | Sixth | 17 out |
| Sunday, July 19 |
| » Lost to Cardinals (58-32), 5-4 | San Diego/Jack Murphy Stadium (17-26) | 32-60 | |
| » W: Ken Dayley (3-1) L: Rich Gossage (2-3) S: Todd Worrell (20) | Sixth | 17 out |
| Monday, July 20 |
| » Defeated Cubs (49-44), 7-4 | San Diego/Jack Murphy Stadium (18-26) | 33-60 | |
| » W: Lance McCullers (6-6) L: Bob Tewksbury (1-5) S: Mark Davis (2) | Fifth | 17 out |
| Tuesday, July 21 |
| » Defeated Cubs (49-45), 4-3 | San Diego/Jack Murphy Stadium (19-26) | 34-60 | Won 2 |
| » W: Mark Davis (5-5) L: Jamie Moyer (9-7) | Sixth | 17 out |
| Wednesday, July 22 |
| » Lost to Cubs (50-45), 6-3 | San Diego/Jack Murphy Stadium (19-27) | 34-61 | |
| » W: Rick Sutcliffe (14-4) L: Mark Grant (2-5) | Sixth | 17 out |
| Thursday, July 23 |
| » Defeated Pirates (43-52), 2-1 | San Diego/Jack Murphy Stadium (20-27) | 35-61 | |
| » W: Eric Show (5-11) L: Doug Drabek (2-9) S: Rich Gossage (7) | Sixth | 17 out |
| Friday, July 24 |
| » Lost to Pirates (44-52), 3-2 | San Diego/Jack Murphy Stadium (20-28) | 35-62 | |
| » W: Mike Dunne (6-4) L: Jimmy Jones (2-4) S: Brett Gideon (2) | Sixth | 17 out |
| Saturday, July 25 |
| » Lost to Pirates (45-52), 9-3 | San Diego/Jack Murphy Stadium (20-29) | 35-63 | Lost 2 |
| » W: Brian Fisher (6-6) L: Andy Hawkins (3-9) | Sixth | 17 out |
| Sunday, July 26 |
| » Defeated Pirates (45-53), 7-4 | San Diego/Jack Murphy Stadium (21-29) | 36-63 | |
| » W: Ed Whitson (9-7) L: Bob Kipper (5-9) | Fifth | 16 out |
| Monday, July 27 |
| » Major-league debuts: Tim Crews (Dodgers) |
| Tuesday, July 28 |
| » Lost to Reds (53-47), 8-7 | Riverfront Stadium (1-3) | 36-64 | |
| » W: John Franco (7-3) L: Mark Davis (5-6) | Sixth | 17 out |
| Wednesday, July 29 |
| » Lost to Reds (54-47), 15-5 | Riverfront Stadium (1-4) | 36-65 | Lost 2 |
| » W: Rob Murphy (5-3) L: Eric Show (5-12) | Sixth | 18 out |
| Thursday, July 30 |
| » Defeated Reds (54-48), 12-8 | Riverfront Stadium (2-4) | 37-65 | |
| » W: Jimmy Jones (3-4) L: Guy Hoffman (7-6) | Fifth | 17 out |
| Friday, July 31 |
| » Defeated Astros (50-52), 6-2 | Astrodome (2-2) | 38-65 | Won 2 |
| » W: Ed Whitson (10-7) L: Danny Darwin (7-7) S: Lance McCullers (10) | Sixth | 17 out |
| Saturday, August 1 |
| » Defeated Astros (50-53), 6-0 | Astrodome (3-2) | 39-65 | Won 3 |
| » W: Eric Nolte (1-0) L: Jeff Heathcock (0-1) | Sixth | 16 out |
| » Major-league debuts: Eric Nolte (Padres) |
| Sunday, August 2 |
| » Lost to Astros (51-53), 6-0 | Astrodome (3-3) | 39-66 | |
| » W: Mike Scott (12-7) L: Mark Grant (2-6) | Sixth | 17 out |
| Tuesday, August 4 |
| » Lost to Braves (47-58), 12-7 | Atlanta-Fulton County Stadium (2-2) | 39-67 | Lost 2 |
| » W: Charlie Puleo (5-3) L: Eric Show (5-13) | Sixth | 17½ out |
| Wednesday, August 5 |
| » Defeated Braves (47-59), 7-3 | Atlanta-Fulton County Stadium (3-2) | 40-67 | |
| » W: Jimmy Jones (4-4) L: Doyle Alexander (5-9) S: Rich Gossage (8) | Sixth | 17½ out |
| Thursday, August 6 |
| » Defeated Braves (47-60), 7-4 | Atlanta-Fulton County Stadium (4-2) | 41-67 | Won 2 |
| » W: Lance McCullers (7-6) L: Gene Garber (8-8) S: Rich Gossage (9) | Sixth | 17 out |
| Friday, August 7 |
| » Defeated Astros (54-54), 7-1 | San Diego/Jack Murphy Stadium (22-29) | 42-67 | Won 3 |
| » W: Mark Davis (6-6) L: Mike Scott (12-8) S: Lance McCullers (11) | Fifth | 16 out |
| Saturday, August 8 |
| » Defeated Astros (54-55), 4-3 | San Diego/Jack Murphy Stadium (23-29) | 43-67 | Won 4 |
| » W: Rich Gossage (3-3) L: Dave Meads (5-2) | Sixth | 15 out |
| Sunday, August 9 |
| » Defeated Astros (54-56), 4-3 | San Diego/Jack Murphy Stadium (24-29) | 44-67 | Won 5 |
| » W: Eric Show (6-13) L: Bob Knepper (4-13) S: Rich Gossage (10) | Fifth | 13½ out |
| Monday, August 10 |
| » Defeated Braves (49-62), 2-0 | San Diego/Jack Murphy Stadium (25-29) | 45-67 | Won 6 |
| » W: Jimmy Jones (5-4) L: Doyle Alexander (5-10) | Fifth | 13½ out |
| Tuesday, August 11 |
| » Defeated Braves (49-63), 7-6 | San Diego/Jack Murphy Stadium (26-29) | 46-67 | Won 7 |
| » W: Mark Davis (7-6) L: Gene Garber (8-9) | Sixth | 12½ out |
| Wednesday, August 12 |
| » Lost to Braves (50-63), 2-1 | San Diego/Jack Murphy Stadium (26-30) | 46-68 | |
| » W: Zane Smith (12-6) L: Eric Nolte (1-1) | Fifth | 12½ out |
| Thursday, August 13 |
| » Defeated Braves (50-64), 5-3 | San Diego/Jack Murphy Stadium (27-30) | 47-68 | |
| » W: Mark Grant (3-6) L: David Palmer (6-10) S: Lance McCullers (12) | Fifth | 12½ out |
| Friday, August 14 |
| » Lost to Reds (61-56), 2-0 | San Diego/Jack Murphy Stadium (27-31) | 47-69 | |
| » W: Ted Power (9-7) L: Eric Show (6-14) S: John Franco (22) | Sixth | 12½ out |
| » Defeated Reds (61-57), 15-8 | San Diego/Jack Murphy Stadium (28-31) | 48-69 | |
| » W: Greg Booker (1-1) L: Guy Hoffman (8-8) | Sixth | 12½ out |
| Sunday, August 16 |
| » Lost to Reds (62-57), 2-0 | San Diego/Jack Murphy Stadium (28-32) | 48-70 | |
| » W: Ron Robinson (6-3) L: Ed Whitson (10-8) S: John Franco (23) | Fifth | 13½ out |
| Monday, August 17 |
| » Major-league debuts: Tom Glavine (Braves) |
| Tuesday, August 18 |
| » Defeated Phillies (61-57), 9-4 | Veteran's Stadium (2-2) | 49-70 | |
| » W: Rich Gossage (4-3) L: Wally Ritchie (2-1) | Fifth | 12½ out |
| Wednesday, August 19 |
| » Lost to Phillies (62-57), 6-5 | Veteran's Stadium (2-3) | 49-71 | |
| » W: Bruce Ruffin (10-9) L: Mark Grant (3-7) S: Jeff Calhoun (1) | Sixth | 13½ out |
| Thursday, August 20 |
| » Lost to Phillies (63-57), 10-2 | Veteran's Stadium (2-4) | 49-72 | Lost 2 |
| » W: Freddie Toliver (1-0) L: Eric Show (6-15) S: Wally Ritchie (3) | Fifth | 13½ out |
| Friday, August 21 |
| » Defeated Mets (68-54), 6-2 | Shea Stadium (2-2) | 50-72 | |
| » W: Jimmy Jones (6-4) L: Ron Darling (10-8) | Sixth | 13½ out |
| Saturday, August 22 |
| » Defeated Mets (68-55), 8-3 | Shea Stadium (3-2) | 51-72 | Won 2 |
| » W: Mark Davis (8-6) L: Sid Fernandez (10-7) S: Rich Gossage (11) | Fifth | 12½ out |
| Sunday, August 23 |
| » Lost to Mets (69-55), 9-2 | Shea Stadium (3-3) | 51-73 | |
| » W: Dwight Gooden (11-4) L: Eric Nolte (1-2) S: Roger McDowell (18) | Fifth | 13½ out |
| Tuesday, August 25 |
| » Defeated Expos (68-56), 5-1 | San Diego/Jack Murphy Stadium (29-32) | 52-73 | |
| » W: Mark Grant (4-7) L: Neal Heaton (12-6) S: Lance McCullers (13) | Sixth | 14 out |
| Wednesday, August 26 |
| » Lost to Expos (69-56), 6-5 | San Diego/Jack Murphy Stadium (29-33) | 52-74 | |
| » W: Tim Burke (6-0) L: Lance McCullers (7-7) S: Bob McClure (4) | Sixth | 15 out |
| Thursday, August 27 |
| » Lost to Expos (70-56), 3-0 | San Diego/Jack Murphy Stadium (29-34) | 52-75 | Lost 2 |
| » W: Bryn Smith (8-6) L: Jimmy Jones (6-5) S: Andy McGaffigan (9) | Sixth | 15½ out |
| Friday, August 28 |
| » Lost to Phillies (67-61), 8-1 | San Diego/Jack Murphy Stadium (29-35) | 52-76 | Lost 3 |
| » W: Don Carman (8-9) L: Ed Whitson (10-9) | Sixth | 15½ out |
| Saturday, August 29 |
| » Defeated Phillies (67-62), 3-1 | San Diego/Jack Murphy Stadium (30-35) | 53-76 | |
| » W: Eric Nolte (2-2) L: Bruce Ruffin (10-11) | Sixth | 15½ out |
| Sunday, August 30 |
| » Defeated Phillies (67-63), 6-1 | San Diego/Jack Murphy Stadium (31-35) | 54-76 | Won 2 |
| » W: Mark Grant (5-7) L: Kevin Gross (8-12) | Sixth | 14½ out |
| Monday, August 31 |
| » Lost to Mets (74-57), 6-5 | San Diego/Jack Murphy Stadium (31-36) | 54-77 | |
| » W: Jesse Orosco (3-7) L: Keith Comstock (2-1) S: Roger McDowell (22) | Sixth | 15½ out |
| Tuesday, September 1 |
| » Lost to Mets (75-57), 9-1 | San Diego/Jack Murphy Stadium (31-37) | 54-78 | Lost 2 |
| » W: David Cone (4-3) L: Jimmy Jones (6-6) S: Randy Myers (4) | Sixth | 16½ out |
| Wednesday, September 2 |
| » Lost to Mets (76-57), 4-3 | San Diego/Jack Murphy Stadium (31-38) | 54-79 | Lost 3 |
| » W: Dwight Gooden (13-4) L: Ed Whitson (10-10) | Sixth | 16½ out |
| Friday, September 4 |
| » Lost to Cardinals (80-53), 4-2 | Busch Stadium II (1-3) | 54-80 | Lost 4 |
| » W: Todd Worrell (8-6) L: Mark Davis (8-7) | Sixth | 17½ out |
| Saturday, September 5 |
| » Defeated Cardinals (80-54), 4-1 | Busch Stadium II (2-3) | 55-80 | |
| » W: Mark Grant (6-7) L: Greg Mathews (9-9) S: Lance McCullers (14) | Sixth | 17½ out |
| Sunday, September 6 |
| » Lost to Cardinals (81-54), 6-4 | Busch Stadium II (2-4) | 55-81 | |
| » W: John Tudor (6-2) L: Eric Show (6-16) S: Todd Worrell (28) | Sixth | 18½ out |
| Monday, September 7 |
| » Defeated Braves (58-78), 11-4 | Atlanta-Fulton County Stadium (5-2) | 56-81 | |
| » W: Jimmy Jones (7-6) L: Tom Glavine (1-3) | Sixth | 17½ out |
| Tuesday, September 8 |
| » Lost to Braves (59-78), 4-2 | Atlanta-Fulton County Stadium (5-3) | 56-82 | |
| » W: Pete Smith (1-0) L: Ed Whitson (10-11) S: Jim Acker (9) | Sixth | 18½ out |
| » Major-league debuts: Pete Smith (Braves) Shawn Abner (Padres) |
| Wednesday, September 9 |
| » Lost to Braves (60-78), 3-2 | Atlanta-Fulton County Stadium (5-4) | 56-83 | Lost 2 |
| » W: David Palmer (8-10) L: Eric Nolte (2-3) S: Jim Acker (10) | Sixth | 18½ out |
| Thursday, September 10 |
| » Defeated Astros (70-70), 8-7 | San Diego/Jack Murphy Stadium (32-38) | 57-83 | |
| » W: Rich Gossage (5-3) L: Manny Hernandez (0-3) | Fifth | 18 out |
| Friday, September 11 |
| » Defeated Astros (70-71), 11-0 | San Diego/Jack Murphy Stadium (33-38) | 58-83 | Won 2 |
| » W: Eric Show (7-16) L: Mike Scott (15-11) | Sixth | 17 out |
| Sunday, September 13 |
| » Defeated Astros (70-72), 10-2 | San Diego/Jack Murphy Stadium (34-38) | 59-83 | Won 3 |
| » W: Jimmy Jones (8-6) L: Jim Deshaies (10-6) | Sixth | 17½ out |
| Monday, September 14 |
| » Lost to Giants (78-66), 4-3 | Candlestick Park (3-5) | 59-84 | |
| » W: Craig Lefferts (4-5) L: Lance McCullers (7-8) | Sixth | 18½ out |
| Tuesday, September 15 |
| » Lost to Giants (79-66), 13-3 | Candlestick Park (3-6) | 59-85 | Lost 2 |
| » W: Atlee Hammaker (10-10) L: Eric Nolte (2-4) | Sixth | 19½ out |
| » Major-league debuts: John Burkett and Kirt Manwaring (Giants) |
| Wednesday, September 16 |
| » Defeated Braves (62-82), 3-0 | San Diego/Jack Murphy Stadium (35-38) | 60-85 | |
| » W: Mark Grant (7-7) L: Kevin Coffman (0-3) | Sixth | 19½ out |
| Thursday, September 17 |
| » Defeated Braves (62-83), 7-1 | San Diego/Jack Murphy Stadium (36-38) | 61-85 | Won 2 |
| » W: Eric Show (8-16) L: Zane Smith (15-9) | Sixth | 19½ out |
| Friday, September 18 |
| » Defeated Astros (71-76), 2-1 | Astrodome (4-3) | 62-85 | Won 3 |
| » W: Lance McCullers (8-8) L: Dave Smith (2-1) | Sixth | 19 out |
| Saturday, September 19 |
| » Defeated Astros (71-77), 2-1 | Astrodome (5-3) | 63-85 | Won 4 |
| » W: Dave Leiper (3-1) L: Manny Hernandez (0-4) S: Lance McCullers (15) | Fifth | 19 out |
| Sunday, September 20 |
| » Lost to Astros (72-77), 3-2 | Astrodome (5-4) | 63-86 | |
| » W: Mike Scott (16-12) L: Mark Davis (8-8) | Sixth | 19 out |
| Tuesday, September 22 |
| » Lost to Reds (75-75), 5-3 | Riverfront Stadium (2-5) | 63-87 | Lost 2 |
| » W: Dennis Rasmussen (12-8) L: Mark Grant (7-8) S: John Franco (27) | Sixth | 18½ out |
| Wednesday, September 23 |
| » Defeated Reds (75-76), 6-4 | Riverfront Stadium (3-5) | 64-87 | |
| » W: Mark Davis (9-8) L: Jeff Montgomery (1-2) S: Dave Leiper (2) | Sixth | |