| Thursday, January 8 |
| Former Giant Frank Hiller dies in West Chester, PA at the age of 67. |
| Tuesday, January 20 |
| Former Giant Hank Behrman dies in New York, NY at the age of 66. |
| Wednesday, February 11 |
| Former Giant Bill McGee dies in St.Louis, MO at the age of 78. |
| Monday, March 9 |
| Former Giant Zeke Bonura dies in New Orleans, LA at the age of 79. |
| Monday, April 6 |
| » Defeated Padres (0-1), 4-3 | Candlestick Park (1-0) | 1-0 | |
| » W: Jeff Robinson (1-0) L: Dave Dravecky (0-1) | First | -- |
| » Major-league debuts: Joey Cora (Padres) |
| Tuesday, April 7 |
| » Defeated Padres (0-2), 4-3 | Candlestick Park (2-0) | 2-0 | Won 2 |
| » W: Mike LaCoss (1-0) L: Ed Whitson (0-1) S: Jeff Robinson (1) | First | -- |
| Wednesday, April 8 |
| » Defeated Padres (0-3), 2-1 | Candlestick Park (3-0) | 3-0 | Won 3 |
| » W: Roger Mason (1-0) L: Andy Hawkins (0-1) S: Scott Garrelts (1) | First | -- |
| Thursday, April 9 |
| » Defeated Dodgers (0-4), 8-1 | Dodger Stadium (1-0) | 4-0 | Won 4 |
| » W: Mark Davis (1-0) L: Bob Welch (0-1) | First | -- |
| Friday, April 10 |
| » Defeated Dodgers (0-5), 5-4 | Dodger Stadium (2-0) | 5-0 | Won 5 |
| » W: Scott Garrelts (1-0) L: Tim Leary (0-1) S: Mark Grant (1) | First | -- |
| Saturday, April 11 |
| » Lost to Dodgers (1-5), 5-1 | Dodger Stadium (2-1) | 5-1 | |
| » W: Orel Hershiser (1-1) L: Mike Krukow (0-1) | Third | ½ out |
| » Major-league debuts: Matt Williams (Giants) |
| Sunday, April 12 |
| » Lost to Dodgers (2-5), 7-5 | Dodger Stadium (2-2) | 5-2 | Lost 2 |
| » W: Fernando Valenzuela (1-0) L: Mike LaCoss (1-1) S: Matt Young (1) | Third | 1½ out |
| Monday, April 13 |
| » Defeated Padres (1-6), 13-6 | San Diego/Jack Murphy Stadium (1-0) | 6-2 | |
| » W: Jim Gott (1-0) L: Dave Dravecky (0-3) S: Jeff Robinson (2) | Third | ½ out |
| Tuesday, April 14 |
| » Defeated Padres (1-7), 3-2 | San Diego/Jack Murphy Stadium (2-0) | 7-2 | Won 2 |
| » W: Mark Grant (1-0) L: Ed Wojna (0-1) S: Scott Garrelts (2) | Second | 1 out |
| Wednesday, April 15 |
| » Defeated Padres (1-8), 1-0 | San Diego/Jack Murphy Stadium (3-0) | 8-2 | Won 3 |
| » W: Kelly Downs (1-0) L: Storm Davis (0-1) | First | -- |
| Friday, April 17 |
| » Lost to Braves (6-3), 2-0 | Candlestick Park (3-1) | 8-3 | |
| » W: Zane Smith (1-1) L: Mike Krukow (0-2) | Second | 1 out |
| Saturday, April 18 |
| » Defeated Braves (6-4), 2-1 | Candlestick Park (4-1) | 9-3 | |
| » W: Scott Garrelts (2-0) L: Gene Garber (2-1) | Second | 1 out |
| Sunday, April 19 |
| » Defeated Braves (6-5), 4-3 | Candlestick Park (5-1) | 10-3 | Won 2 |
| » W: Jeff Robinson (2-0) L: Paul Assenmacher (0-1) | First | -- |
| Monday, April 20 |
| » Defeated Dodgers (7-8), 4-3 | Candlestick Park (6-1) | 11-3 | Won 3 |
| » W: Mark Davis (2-0) L: Orel Hershiser (1-2) S: Scott Garrelts (3) | First | -- |
| Tuesday, April 21 |
| » Lost to Dodgers (8-8), 11-8 | Candlestick Park (6-2) | 11-4 | |
| » W: Ken Howell (2-0) L: Scott Garrelts (2-1) | First | -- |
| Wednesday, April 22 |
| » Lost to Dodgers (9-8), 5-3 | Candlestick Park (6-3) | 11-5 | Lost 2 |
| » W: Fernando Valenzuela (3-0) L: Mike Krukow (0-3) S: Tom Niedenfuer (1) | First | -- |
| Friday, April 24 |
| » Defeated Braves (6-9), 7-5 | Atlanta-Fulton County Stadium (1-0) | 12-5 | |
| » W: Greg Minton (1-0) L: Jim Acker (0-1) S: Jeff Robinson (3) | First | -- |
| Saturday, April 25 |
| » Lost to Braves (7-9), 5-3 | Atlanta-Fulton County Stadium (1-1) | 12-6 | |
| » W: Gene Garber (3-2) L: Scott Garrelts (2-2) | Second | 1 out |
| Sunday, April 26 |
| » Defeated Braves (7-10), 6-4 | Atlanta-Fulton County Stadium (2-1) | 13-6 | |
| » W: Mark Davis (3-0) L: David Palmer (0-4) S: Jeff Robinson (4) | Second | 1 out |
| Monday, April 27 |
| » Defeated Braves (7-11), 7-3 | Atlanta-Fulton County Stadium (3-1) | 14-6 | Won 2 |
| » W: Kelly Downs (2-0) L: Rick Mahler (2-2) S: Scott Garrelts (4) | Second | ½ out |
| Tuesday, April 28 |
| » Defeated Cubs (9-9), 6-2 | Wrigley Field (1-0) | 15-6 | Won 3 |
| » W: Mike Krukow (1-3) L: Rick Sutcliffe (3-2) | First | -- |
| Wednesday, April 29 |
| » Lost to Cubs (10-9), 8-4 | Wrigley Field (1-1) | 15-7 | |
| » W: Greg Maddux (1-2) L: Roger Mason (1-1) S: Ed Lynch (1) | First | -- |
| Thursday, April 30 |
| » Defeated Cubs (10-10), 5-4 | Wrigley Field (2-1) | 16-7 | |
| » W: Scott Garrelts (3-2) L: Lee Smith (0-2) S: Greg Minton (1) | First | -- |
| Friday, May 1 |
| » Lost to Pirates (9-11), 4-2 | Three Rivers Stadium (0-1) | 16-8 | |
| » W: Rick Reuschel (1-1) L: Mark Davis (3-1) | Second | ½ out |
| Saturday, May 2 |
| » Lost to Pirates (10-11), 1-0 | Three Rivers Stadium (0-2) | 16-9 | Lost 2 |
| » W: John Smiley (2-0) L: Kelly Downs (2-1) S: Don Robinson (4) | Second | ½ out |
| Monday, May 4 |
| » Defeated Cardinals (13-10), 10-7 | Busch Stadium II (1-0) | 17-9 | |
| » W: Mike LaCoss (2-1) L: Bill Dawley (0-3) S: Jeff Robinson (5) | Second | ½ out |
| Tuesday, May 5 |
| » Defeated Cardinals (13-11), 10-6 | Busch Stadium II (2-0) | 18-9 | Won 2 |
| » W: Scott Garrelts (4-2) L: Greg Mathews (2-3) | Second | ½ out |
| Wednesday, May 6 |
| » Lost to Cubs (15-11), 9-4 | Candlestick Park (6-4) | 18-10 | |
| » W: Scott Sanderson (2-0) L: Mark Davis (3-2) S: Lee Smith (7) | Second | ½ out |
| Thursday, May 7 |
| » Defeated Cubs (15-12), 11-1 | Candlestick Park (7-4) | 19-10 | |
| » W: Mike LaCoss (3-1) L: Ed Lynch (1-2) S: Jeff Robinson (6) | Second | 1 out |
| Friday, May 8 |
| » Defeated Pirates (11-15), 4-2 | Candlestick Park (8-4) | 20-10 | Won 2 |
| » W: Kelly Downs (3-1) L: Brian Fisher (0-1) S: Scott Garrelts (5) | Second | 1 out |
| Saturday, May 9 |
| » Defeated Pirates (11-16), 9-4 | Candlestick Park (9-4) | 21-10 | Won 3 |
| » W: Atlee Hammaker (1-0) L: Bob Walk (1-1) | First | -- |
| Sunday, May 10 |
| » Lost to Pirates (12-16), 4-1 | Candlestick Park (9-5) | 21-11 | |
| » W: Don Robinson (3-1) L: Scott Garrelts (4-3) | First | -- |
| Tuesday, May 12 |
| » Lost to Cardinals (17-13), 6-5 | Candlestick Park (9-6) | 21-12 | Lost 2 |
| » W: Joe Magrane (3-0) L: Mark Davis (3-3) S: Todd Worrell (4) | First | -- |
| Wednesday, May 13 |
| » Lost to Cardinals (18-13), 7-6 | Candlestick Park (9-7) | 21-13 | Lost 3 |
| » W: Ray Soff (1-0) L: Jeff Robinson (2-1) S: Todd Worrell (5) | Second | ½ out |
| Friday, May 15 |
| » Lost to Mets (15-18), 8-3 | Shea Stadium (0-1) | 21-14 | Lost 4 |
| » W: Sid Fernandez (5-2) L: Mike Krukow (1-4) S: Roger McDowell (1) | Second | 1 out |
| Saturday, May 16 |
| » Defeated Mets (15-19), 5-4 | Shea Stadium (1-1) | 22-14 | |
| » W: Scott Garrelts (5-3) L: Jeff Innis (0-1) | First | -- |
| » Major-league debuts: Jeff Innis (Mets) |
| Sunday, May 17 |
| » Lost to Mets (16-19), 6-4 | Shea Stadium (1-2) | 22-15 | |
| » W: David Cone (2-2) L: Atlee Hammaker (1-1) S: Roger McDowell (2) | First | -- |
| Monday, May 18 |
| » Lost to Expos (19-18), 7-2 | Stade Olympique (0-1) | 22-16 | Lost 2 |
| » W: Neal Heaton (4-2) L: Kelly Downs (3-2) | Second | ½ out |
| Tuesday, May 19 |
| » Defeated Expos (19-19), 6-2 | Stade Olympique (1-1) | 23-16 | |
| » W: Mike LaCoss (4-1) L: Floyd Youmans (1-3) | First | -- |
| Wednesday, May 20 |
| » Defeated Expos (19-20), 9-7 | Stade Olympique (2-1) | 24-16 | Won 2 |
| » W: Jeff Robinson (3-1) L: Randy St. Claire (2-3) | First | -- |
| Friday, May 22 |
| » Defeated Phillies (16-22), 2-1 | Veteran's Stadium (1-0) | 25-16 | Won 3 |
| » W: Atlee Hammaker (2-1) L: Don Carman (2-3) S: Scott Garrelts (6) | First | -- |
| Saturday, May 23 |
| » Lost to Phillies (17-22), 9-8 | Veteran's Stadium (1-1) | 25-17 | |
| » W: Steve Bedrosian (3-1) L: Jeff Robinson (3-2) | First | -- |
| Sunday, May 24 |
| » Defeated Phillies (17-23), 6-3 | Veteran's Stadium (2-1) | 26-17 | |
| » W: Mike LaCoss (5-1) L: Kent Tekulve (1-2) S: Jeff Robinson (7) | First | -- |
| Monday, May 25 |
| » Lost to Mets (20-22), 8-7 | Candlestick Park (9-8) | 26-18 | |
| » W: Terry Leach (2-0) L: Mark Grant (1-1) S: Jesse Orosco (8) | First | -- |
| Tuesday, May 26 |
| » Lost to Mets (21-22), 3-2 | Candlestick Park (9-9) | 26-19 | Lost 2 |
| » W: Doug Sisk (1-0) L: Jeff Robinson (3-3) S: Jesse Orosco (9) | First | -- |
| Wednesday, May 27 |
| » Lost to Mets (22-22), 4-3 | Candlestick Park (9-10) | 26-20 | Lost 3 |
| » W: Roger McDowell (2-1) L: Jeff Robinson (3-4) S: Jesse Orosco (10) | First | -- |
| Friday, May 29 |
| » Lost to Expos (24-22), 10-4 | Candlestick Park (9-11) | 26-21 | Lost 4 |
| » W: Neal Heaton (6-2) L: Mike LaCoss (5-2) S: Tim Burke (5) | First | -- |
| Saturday, May 30 |
| » Lost to Expos (25-22), 6-4 | Candlestick Park (9-12) | 26-22 | Lost 5 |
| » W: Floyd Youmans (3-3) L: Mike Krukow (1-5) S: Randy St. Claire (5) | Second | 1 out |
| Sunday, May 31 |
| » Defeated Expos (25-23), 8-0 | Candlestick Park (10-12) | 27-22 | |
| » W: Kelly Downs (4-2) L: Bob Sebra (3-5) | Second | 1 out |
| Monday, June 1 |
| » Defeated Phillies (22-25), 9-2 | Candlestick Park (11-12) | 28-22 | Won 2 |
| » W: Atlee Hammaker (3-1) L: Don Carman (3-4) | First | -- |
| Tuesday, June 2 |
| » Lost to Phillies (23-25), 7-6 | Candlestick Park (11-13) | 28-23 | |
| » W: Wally Ritchie (1-0) L: Mark Davis (3-4) S: Steve Bedrosian (12) | Second | 1 out |
| Wednesday, June 3 |
| » Defeated Phillies (23-26), 4-1 | Candlestick Park (12-13) | 29-23 | |
| » W: Mike LaCoss (6-2) L: Bruce Ruffin (3-5) S: Jeff Robinson (8) | Second | 1 out |
| Friday, June 5 |
| » Lost to Astros (26-26), 6-1 | Astrodome (0-1) | 29-24 | |
| » W: Mike Scott (6-3) L: Mike Krukow (1-6) | Second | 2 out |
| Saturday, June 6 |
| » Defeated Astros (26-27), 4-3 | Astrodome (1-1) | 30-24 | |
| » W: Keith Comstock (1-0) L: Larry Andersen (4-3) | Second | 2 out |
| Sunday, June 7 |
| » Lost to Astros (27-27), 3-0 | Astrodome (1-2) | 30-25 | |
| » W: Nolan Ryan (3-5) L: Atlee Hammaker (3-2) S: Dave Smith (10) | Second | 2 out |
| Monday, June 8 |
| » Lost to Reds (33-23), 7-6 | Riverfront Stadium (0-1) | 30-26 | Lost 2 |
| » W: John Franco (3-1) L: Scott Garrelts (5-4) | Second | 3 out |
| Tuesday, June 9 |
| » Defeated Reds (33-24), 10-2 | Riverfront Stadium (1-1) | 31-26 | |
| » W: Mark Davis (4-4) L: Pat Pacillo (1-2) | Second | 2 out |
| Wednesday, June 10 |
| » Defeated Reds (33-25), 9-4 | Riverfront Stadium (2-1) | 32-26 | Won 2 |
| » W: Keith Comstock (2-0) L: Bill Gullickson (7-3) S: Scott Garrelts (7) | Second | 1 out |
| Thursday, June 11 |
| » Defeated Padres (15-46), 1-0 | Candlestick Park (13-13) | 33-26 | Won 3 |
| » W: Kelly Downs (5-2) L: Eric Show (2-8) | First | -- |
| Friday, June 12 |
| » Lost to Padres (16-46), 5-0 | Candlestick Park (13-14) | 33-27 | |
| » W: Ed Whitson (7-6) L: Mike LaCoss (6-3) | First | -- |
| Saturday, June 13 |
| » Lost to Padres (17-46), 11-2 | Candlestick Park (13-15) | 33-28 | Lost 2 |
| » W: Andy Hawkins (3-7) L: Atlee Hammaker (3-3) S: Craig Lefferts (2) | Second | 1 out |
| Sunday, June 14 |
| » Lost to Padres (18-46), 4-1 | Candlestick Park (13-16) | 33-29 | Lost 3 |
| » W: Dave Dravecky (2-6) L: Mark Davis (4-5) | Second | 2 out |
| Tuesday, June 16 |
| » Lost to Braves (31-32), 7-2 | Atlanta-Fulton County Stadium (3-2) | 33-30 | Lost 4 |
| » W: Doyle Alexander (3-1) L: Kelly Downs (5-3) | Third | 1½ out |
| Wednesday, June 17 |
| » Lost to Braves (32-32), 6-1 | Atlanta-Fulton County Stadium (3-3) | 33-31 | Lost 5 |
| » W: Rick Mahler (4-7) L: Jeff Robinson (3-5) | Third | 2½ out |
| Thursday, June 18 |
| » Lost to Padres (21-46), 3-1 | San Diego/Jack Murphy Stadium (3-1) | 33-32 | Lost 6 |
| » W: Storm Davis (2-7) L: Atlee Hammaker (3-4) S: Rich Gossage (5) | Third | 3½ out |
| Friday, June 19 |
| » Defeated Padres (21-47), 7-6 | San Diego/Jack Murphy Stadium (4-1) | 34-32 | |
| » W: Jeff Robinson (4-5) L: Lance McCullers (3-4) S: Scott Garrelts (8) | Third | 2½ out |
| Saturday, June 20 |
| » Lost to Padres (22-47), 10-4 | San Diego/Jack Murphy Stadium (4-2) | 34-33 | |
| » W: Jimmy Jones (1-3) L: Jeff Robinson (4-6) S: Lance McCullers (8) | Third | 2½ out |
| Sunday, June 21 |
| » Defeated Padres (22-48), 11-2 | San Diego/Jack Murphy Stadium (5-2) | 35-33 | |
| » W: Kelly Downs (6-3) L: Eric Show (2-9) | Third | 2½ out |
| Former Giant Phil Weintraub dies in Palm Springs, CA at the age of 80. |
| Tuesday, June 23 |
| » Lost to Reds (39-31), 4-1 | Candlestick Park (13-17) | 35-34 | |
| » W: Ron Robinson (3-2) L: Atlee Hammaker (3-5) S: John Franco (15) | Third | 3½ out |
| Wednesday, June 24 |
| » Lost to Reds (40-31), 5-4 | Candlestick Park (13-18) | 35-35 | Lost 2 |
| » W: John Franco (4-1) L: Scott Garrelts (5-5) | Third | 4½ out |
| Thursday, June 25 |
| » Defeated Reds (40-32), 7-6 | Candlestick Park (14-18) | 36-35 | |
| » W: Scott Garrelts (6-5) L: Rob Murphy (4-3) | Third | 3½ out |
| Friday, June 26 |
| » Lost to Astros (39-33), 9-6 | Candlestick Park (14-19) | 36-36 | |
| » W: Bob Knepper (3-8) L: Mike LaCoss (6-4) S: Dave Smith (14) | Third | 4½ out |
| Saturday, June 27 |
| » Lost to Astros (40-33), 6-5 | Candlestick Park (14-20) | 36-37 | Lost 2 |
| » W: Jim Deshaies (8-2) L: Kelly Downs (6-4) S: Larry Andersen (1) | Third | 4½ out |
| Sunday, June 28 |
| » Defeated Astros (40-34), 8-4 | Candlestick Park (15-20) | 37-37 | |
| » W: Atlee Hammaker (4-5) L: Nolan Ryan (4-8) S: Keith Comstock (1) | Third | 3½ out |
| Monday, June 29 |
| » Lost to Braves (36-39), 1-0 | Candlestick Park (15-21) | 37-38 | |
| » W: Zane Smith (8-4) L: Mark Grant (1-2) | Third | 4 out |
| Tuesday, June 30 |
| » Defeated Braves (36-40), 5-2 | Candlestick Park (16-21) | 38-38 | |
| » W: Jeff Robinson (5-6) L: Doyle Alexander (4-3) S: Scott Garrelts (9) | Third | 4 out |
| Wednesday, July 1 |
| » Lost to Braves (37-40), 8-3 | Candlestick Park (16-22) | 38-39 | |
| » W: Rick Mahler (5-8) L: Mike LaCoss (6-5) | Third | 5 out |
| Friday, July 3 |
| » Defeated Cubs (41-38), 3-1 | Wrigley Field (3-1) | 39-39 | |
| » W: Kelly Downs (7-4) L: Jamie Moyer (8-6) S: Jeff Robinson (9) | Third | 4½ out |
| Saturday, July 4 |
| » Lost to Cubs (42-38), 5-3 | Wrigley Field (3-2) | 39-40 | |
| » W: Rick Sutcliffe (11-4) L: Atlee Hammaker (4-6) S: Lee Smith (21) | Third | 5½ out |
| Sunday, July 5 |
| » Defeated Cubs (42-39), 7-5 | Wrigley Field (4-2) | 40-40 | |
| » W: Joe Price (1-0) L: Ed Lynch (1-6) S: Scott Garrelts (10) | Third | 5½ out |
| Monday, July 6 |
| » Defeated Pirates (36-45), 7-5 | Three Rivers Stadium (1-2) | 41-40 | Won 2 |
| » W: Dave Dravecky (4-7) L: Mike Dunne (3-4) S: Scott Garrelts (11) | Third | 4 out |
| » Defeated Pirates (36-46), 7-4 | Three Rivers Stadium (2-2) | 42-40 | Won 3 |
| » W: Mike LaCoss (7-5) L: Doug Drabek (1-8) S: Craig Lefferts (3) | Third | 4 out |
| Tuesday, July 7 |
| » Lost to Pirates (37-46), 6-4 | Three Rivers Stadium (2-3) | 42-41 | |
| » W: Brett Gideon (1-0) L: Joe Price (1-1) | Third | 4 out |
| Wednesday, July 8 |
| » Defeated Pirates (37-47), 8-4 | Three Rivers Stadium (3-3) | 43-41 | |
| » W: Jeff Robinson (6-6) L: Brett Gideon (1-1) | Third | 3 out |
| » Major-league debuts: Felix Fermin (Pirates) |
| Thursday, July 9 |
| » Lost to Cardinals (54-29), 7-6 | Busch Stadium II (2-1) | 43-42 | |
| » W: Ricky Horton (4-0) L: Scott Garrelts (6-6) | Third | 4 out |
| Friday, July 10 |
| » Lost to Cardinals (55-29), 7-5 | Busch Stadium II (2-2) | 43-43 | Lost 2 |
| » W: Lee Tunnell (4-2) L: Craig Lefferts (2-3) | Third | 4 out |
| » Major-league debuts: Lance Johnson (Cardinals) |
| Saturday, July 11 |
| » Defeated Cardinals (55-30), 3-1 | Busch Stadium II (3-2) | 44-43 | |
| » W: Kelly Downs (8-4) L: Joe Magrane (5-2) S: Scott Garrelts (12) | Third | 3 out |
| Sunday, July 12 |
| » Lost to Cardinals (56-30), 3-2 | Busch Stadium II (3-3) | 44-44 | |
| » W: Ricky Horton (5-0) L: Atlee Hammaker (4-7) S: Ken Dayley (2) | Third | 3 out |
| Thursday, July 16 |
| » Lost to Cubs (48-41), 4-1 | Candlestick Park (16-23) | 44-45 | Lost 2 |
| » W: Jamie Moyer (9-6) L: Dave Dravecky (4-8) S: Scott Sanderson (2) | Third | 3 out |
| Friday, July 17 |
| » Lost to Cubs (49-41), 5-1 | Candlestick Park (16-24) | 44-46 | Lost 3 |
| » W: Rick Sutcliffe (13-4) L: Kelly Downs (8-5) S: Lee Smith (23) | Third | 4 out |
| » Major-league debuts: Mackey Sasser (Giants) |
| Saturday, July 18 |
| » Defeated Cubs (49-42), 9-2 | Candlestick Park (17-24) | 45-46 | |
| » W: Atlee Hammaker (5-7) L: Greg Maddux (5-8) | Third | 4 out |
| Sunday, July 19 |
| » Defeated Cubs (49-43), 4-3 | Candlestick Park (18-24) | 46-46 | Won 2 |
| » W: Scott Garrelts (7-6) L: Scott Sanderson (4-5) | Second | 3 out |
| Monday, July 20 |
| » Lost to Pirates (42-50), 7-6 | Candlestick Park (18-25) | 46-47 | |
| » W: Brian Fisher (5-6) L: Mike LaCoss (7-6) S: Don Robinson (12) | Second | 4 out |
| Tuesday, July 21 |
| » Defeated Pirates (42-51), 7-0 | Candlestick Park (19-25) | 47-47 | |
| » W: Dave Dravecky (5-8) L: Bob Kipper (5-8) | Second | 4 out |
| Wednesday, July 22 |
| » Lost to Pirates (43-51), 4-0 | Candlestick Park (19-26) | 47-48 | |
| » W: Rick Reuschel (8-4) L: Kelly Downs (8-6) | Third | 4 out |
| Former Giant Don McMahon dies in Los Angeles, CA at the age of 58. |
| Friday, July 24 |
| » Defeated Cardinals (61-33), 4-3 | Candlestick Park (20-26) | 48-48 | |
| » W: Atlee Hammaker (6-7) L: Ricky Horton (5-1) S: Jeff Robinson (10) | Second | 3½ out |
| Saturday, July 25 |
| » Defeated Cardinals (61-34), 5-4 | Candlestick Park (21-26) | 49-48 | Won 2 |
| » W: Scott Garrelts (8-6) L: Bill Dawley (4-7) | Second | 2½ out |
| Sunday, July 26 |
| » Defeated Cardinals (61-35), 6-3 | Candlestick Park (22-26) | 50-48 | Won 3 |
| » W: Scott Garrelts (9-6) L: Todd Worrell (4-5) | Second | 1 out |
| » Defeated Cardinals (61-36), 5-2 | Candlestick Park (23-26) | 51-48 | Won 4 |
| » W: Mike LaCoss (8-6) L: Greg Mathews (7-7) S: Craig Lefferts (4) | Second | 1 out |
| Monday, July 27 |
| » Lost to Dodgers (44-55), 6-5 | Dodger Stadium (2-3) | 51-49 | |
| » W: Tim Leary (2-6) L: Scott Garrelts (9-7) | Second | 1½ out |
| » Major-league debuts: Tim Crews (Dodgers) |
| Former Giant Travis Jackson dies in Waldo, AR at the age of 84. |
| Tuesday, July 28 |
| » Lost to Dodgers (45-55), 4-2 | Dodger Stadium (2-4) | 51-50 | Lost 2 |
| » W: Orel Hershiser (11-9) L: Atlee Hammaker (6-8) S: Ken Howell (1) | Second | 2½ out |
| Wednesday, July 29 |
| » Defeated Dodgers (45-56), 16-2 | Dodger Stadium (3-4) | 52-50 | |
| » W: Mike Krukow (2-6) L: Rick Honeycutt (2-11) | Second | 2½ out |
| Friday, July 31 |
| » Lost to Reds (55-48), 9-2 | Riverfront Stadium (2-2) | 52-51 | |
| » W: Ron Robinson (4-3) L: Dave Dravecky (5-9) | Second | 3 out |
| Saturday, August 1 |
| » Defeated Reds (55-49), 7-3 | Riverfront Stadium (3-2) | 53-51 | |
| » W: Mike LaCoss (9-6) L: Bill Gullickson (10-8) | Second | 2 out |
| » Major-league debuts: Jeff Montgomery (Reds) |
| Sunday, August 2 |
| » Lost to Reds (56-49), 5-4 | Riverfront Stadium (3-3) | 53-52 | |
| » W: Jeff Montgomery (1-0) L: Jeff Robinson (6-7) | Second | 3 out |
| Monday, August 3 |
| » Lost to Astros (52-53), 5-3 | Astrodome (1-3) | 53-53 | Lost 2 |
| » W: Juan Agosto (1-0) L: Joe Price (1-2) | Second | 3 out |
| Tuesday, August 4 |
| » Lost to Astros (53-53), 5-4 | Astrodome (1-4) | 53-54 | Lost 3 |
| » W: Jeff Heathcock (1-1) L: Craig Lefferts (2-4) S: Dave Smith (19) | Third | 4 out |
| Wednesday, August 5 |
| » Lost to Astros (54-53), 6-5 | Astrodome (1-5) | 53-55 | Lost 4 |
| » W: Larry Andersen (7-4) L: Jeff Robinson (6-8) | Third | 5 out |
| Friday, August 7 |
| » Defeated Reds (58-51), 3-1 | Candlestick Park (24-26) | 54-55 | |
| » W: Mike LaCoss (10-6) L: Bill Gullickson (10-9) | Third | 4 out |
| Saturday, August 8 |
| » Defeated Reds (58-52), 5-2 | Candlestick Park (25-26) | 55-55 | Won 2 |
| » W: Atlee Hammaker (7-8) L: Tom Browning (5-9) | Second | 3 out |
| Sunday, August 9 |
| » Defeated Reds (58-53), 3-2 | Candlestick Park (26-26) | 56-55 | Won 3 |
| » W: Mike Krukow (3-6) L: Ted Power (8-7) S: Don Robinson (13) | Second | 1 out |
| » Defeated Reds (58-54), 5-2 | Candlestick Park (27-26) | 57-55 | Won 4 |
| » W: Kelly Downs (9-6) L: Guy Hoffman (8-7) S: Craig Lefferts (5) | Second | 1 out |
| Monday, August 10 |
| » Defeated Astros (54-57), 6-5 | Candlestick Park (28-26) | 58-55 | Won 5 |
| » W: Don Robinson (7-6) L: Dave Meads (5-3) | Second | 1 out |
| Tuesday, August 11 |
| » Lost to Astros (55-57), 7-3 | Candlestick Park (28-27) | 58-56 | |
| » W: Jeff Heathcock (2-1) L: Mike LaCoss (10-7) S: Larry Andersen (3) | Second | 1 out |
| Wednesday, August 12 |
| » Defeated Astros (55-58), 8-1 | Candlestick Park (29-27) | 59-56 | |
| » W: Atlee Hammaker (8-8) L: Mike Scott (12-9) S: Don Robinson (14) | First | -- |
| Thursday, August 13 |
| » Defeated Astros (55-59), 7-6 | Candlestick Park (30-27) | 60-56 | Won 2 |
| » W: Craig Lefferts (3-4) L: Rocky Childress (0-1) | First | -- |
| Friday, August 14 |
| » Lost to Dodgers (52-63), 4-3 | Candlestick Park (30-28) | 60-57 | |
| » W: Shawn Hillegas (2-0) L: Kelly Downs (9-7) S: Tim Crews (2) | Second | ½ out |
| » Major-league debuts: Chris Gwynn (Dodgers) |
| Saturday, August 15 |
| » Defeated Dodgers (52-64), 5-0 | Candlestick Park (31-28) | 61-57 | |
| » W: Dave Dravecky (6-9) L: Fernando Valenzuela (9-11) | First | -- |
| Sunday, August 16 |
| » Defeated Dodgers (52-65), 1-0 | Candlestick Park (32-28) | 62-57 | Won 2 |
| » W: Mike LaCoss (11-7) L: Tim Leary (3-8) | First | -- |
| Monday, August 17 |
| » Major-league debuts: Tom Glavine (Braves) |
| Tuesday, August 18 |
| » Lost to Mets (67-52), 7-2 | Shea Stadium (1-3) | 62-58 | |
| » W: Dwight Gooden (10-4) L: Atlee Hammaker (8-9) | First | -- |
| Wednesday, August 19 |
| » Defeated Mets (67-53), 10-6 | Shea Stadium (2-3) | 63-58 | |
| » W: Scott Garrelts (10-7) L: Roger McDowell (7-5) | First | -- |
| Thursday, August 20 |
| » Lost to Mets (68-53), 7-4 | Shea Stadium (2-4) | 63-59 | |
| » W: David Cone (3-2) L: Kelly Downs (9-8) S: Randy Myers (3) | First | -- |
| Friday, August 21 |
| » Defeated Expos (67-54), 6-3 | Stade Olympique (3-1) | 64-59 | |
| » W: Dave Dravecky (7-9) L: Dennis Martinez (7-2) S: Don Robinson (15) | First | -- |
| Saturday, August 22 |
| » Lost to Expos (68-54), 5-4 | Stade Olympique (3-2) | 64-60 | |
| » W: Tim Burke (5-0) L: Craig Lefferts (3-5) | First | -- |
| Sunday, August 23 |
| » Defeated Expos (68-55), 5-3 | Stade Olympique (4-2) | 65-60 | |
| » W: Kelly Downs (10-8) L: Bob Sebra (6-14) S: Don Robinson (16) | First | -- |
| Monday, August 24 |
| » Defeated Phillies (66-59), 6-1 | Veteran's Stadium (3-1) | 66-60 | Won 2 |
| » W: Rick Reuschel (9-6) L: Bruce Ruffin (10-10) | First | -- |
| Tuesday, August 25 |
| » Defeated Phillies (66-60), 3-2 | Veteran's Stadium (4-1) | 67-60 | Won 3 |
| » W: Scott Garrelts (11-7) L: Kevin Gross (8-11) | First | -- |
| Wednesday, August 26 |
| » Defeated Phillies (66-61), 2-0 | Veteran's Stadium (5-1) | 68-60 | Won 4 |
| » W: Don Robinson (8-6) L: Shane Rawley (16-6) | First | -- |
| Friday, August 28 |
| » Lost to Mets (72-56), 4-0 | Candlestick Park (32-29) | 68-61 | |
| » W: Dwight Gooden (12-4) L: Mike LaCoss (11-8) | First | -- |
| Saturday, August 29 |
| » Defeated Mets (72-57), 9-1 | Candlestick Park (33-29) | 69-61 | |
| » W: Atlee Hammaker (9-9) L: Sid Fernandez (10-8) | First | -- |
| Sunday, August 30 |
| » Lost to Mets (73-57), 5-3 | Candlestick Park (33-30) | 69-62 | |
| » W: Rick Aguilera (6-2) L: Rick Reuschel (9-7) S: Roger McDowell (21) | First | -- |
| Monday, August 31 |
| » Defeated Expos (73-57), 5-0 | Candlestick Park (34-30) | 70-62 | |
| » W: Dave Dravecky (8-9) L: Dennis Martinez (7-3) | First | -- |
| Tuesday, September 1 |
| » Defeated Expos (73-58), 14-4 | Candlestick Park (35-30) | 71-62 | Won 2 |
| » W: Rick Reuschel (10-7) L: Floyd Youmans (8-7) | First | -- |
| » Major-league debuts: Jack Daugherty (Expos) |
| Wednesday, September 2 |
| » Lost to Expos (74-58), 7-3 | Candlestick Park (35-31) | 71-63 | |
| » W: Pascual Perez (1-0) L: Mike LaCoss (11-9) S: Tim Burke (13) | First | -- |
| Friday, September 4 |
| » Defeated Phillies (70-64), 3-2 | Candlestick Park (36-31) | 72-63 | |
| » W: Don Robinson (9-6) L: Wally Ritchie (3-2) | First | -- |
| Saturday, September 5 |
| » Defeated Phillies (70-65), 6-3 | Candlestick Park (37-31) | 73-63 | Won 2 |
| » W: Dave Dravecky (9-9) L: Shane Rawley (17-7) S: Kelly Downs (1) | First | -- |
| Sunday, September 6 |
| » Defeated Phillies (70-66), 4-1 | Candlestick Park (38-31) | 74-63 | Won 3 |
| » W: Rick Reuschel (11-7) L: Freddie Toliver (1-1) | First | -- |
| Monday, September 7 |
| » Lost to Astros (69-68), 4-2 | Astrodome (1-6) | 74-64 | |
| » W: Mike Scott (15-10) L: Mike LaCoss (11-10) | First | -- |
| Tuesday, September 8 |
| » Defeated Astros (69-69), 6-4 | Astrodome (2-6) | 75-64 | |
| » W: Don Robinson (10-6) L: Larry Andersen (8-5) | First | -- |
| Wednesday, September 9 |
| » Lost to Astros (70-69), 4-2 | Astrodome (2-7) | 75-65 | |
| » W: Nolan Ryan (7-14) L: Atlee Hammaker (9-10) S: Dave Smith (23) | First | -- |
| Friday, September 11 |
| » Lost to Reds (71-70), 4-3 | Riverfront Stadium (3-4) | 75-66 | Lost 2 |
| » W: Dennis Rasmussen (11-8) L: Dave Dravecky (9-10) S: Rob Murphy (3) | First | -- |
| Saturday, September 12 |
| » Defeated Reds (71-71), 7-1 | Riverfront Stadium (4-4) | 76-66 | |
| » W: Rick Reuschel (12-7) L: Ted Power (10-11) | First | -- |
| Sunday, September 13 |
| » Defeated Reds (71-72), 6-1 | Riverfront Stadium (5-4) | 77-66 | Won 2 |
| » W: Mike LaCoss (12-10) L: Tom Browning (7-12) S: Don Robinson (17) | First | -- |
| Monday, September 14 |
| » Defeated Padres (59-84), 4-3 | Candlestick Park (39-31) | 78-66 | Won 3 |
| » W: Craig Lefferts (4-5) L: Lance McCullers (7-8) | First | -- |
| Tuesday, September 15 |
| » Defeated Padres (59-85), 13-3 | Candlestick Park (40-31) | 79-66 | Won 4 |
| » W: Atlee Hammaker (10-10) L: Eric Nolte (2-4) | First | -- |
| » Major-league debuts: John Burkett and Kirt Manwaring (Giants) |
| Wednesday, September 16 |
| » Defeated Astros (71-74), 7-1 | Candlestick Park (41-31) | 80-66 | Won 5 |
| » W: Dave Dravecky (10-10) L: Mike Scott (15-12) | First | -- |
| Thursday, September 17 |
| » Defeated Astros (71-75), 4-0 | Candlestick Park (42-31) | 81-66 | Won 6 |
| » W: Rick Reuschel (13-7) L: Danny Darwin (8-10) | First | -- |
| Saturday, September 19 |
| » Defeated Reds (73-75), 5-1 | Candlestick Park (43-31) | 82-66 | Won 7 |
| » W: Mike LaCoss (13-10) L: Tom Browning (7-13) S: Don Robinson (18) |