| Tuesday, February 25 |
| Former Tiger George Susce dies in Sarasota, FL at the age of 79. |
| Thursday, March 13 |
| Former Tiger Jack Warner dies in Mt.Vernon, IL at the age of 83. |
| Monday, April 7 |
| » Defeated Red Sox (0-1), 6-5 | Tiger Stadium (1-0) | 1-0 | |
| » W: Jack Morris (1-0) L: Sammy Stewart (0-1) S: Guillermo Hernandez (1) | First | -- |
| Wednesday, April 9 |
| » Defeated Red Sox (0-2), 6-5 | Tiger Stadium (2-0) | 2-0 | Won 2 |
| » W: Guillermo Hernandez (1-0) L: Bob Stanley (0-1) | First | -- |
| Thursday, April 10 |
| » Lost to Red Sox (1-2), 4-2 | Tiger Stadium (2-1) | 2-1 | |
| » W: Al Nipper (1-0) L: Dan Petry (0-1) S: Joe Sambito (1) | Second | 1 out |
| Friday, April 11 |
| » Defeated Indians (1-3), 7-2 | Cleveland Stadium (1-0) | 3-1 | |
| » W: Walt Terrell (1-0) L: Phil Niekro (0-1) | First | -- |
| Saturday, April 12 |
| » Lost to Indians (2-3), 6-2 | Cleveland Stadium (1-1) | 3-2 | |
| » W: Ken Schrom (2-0) L: Jack Morris (1-1) S: Ernie Camacho (2) | Second | 1 out |
| Sunday, April 13 |
| » Lost to Indians (3-3), 8-2 | Cleveland Stadium (1-2) | 3-3 | Lost 2 |
| » W: Scott Bailes (1-1) L: Frank Tanana (0-1) | Second | 2 out |
| Monday, April 14 |
| » Defeated White Sox (1-6), 10-8 | Comiskey Park I (1-0) | 4-3 | |
| » W: Dan Petry (1-1) L: Richard Dotson (0-2) S: Guillermo Hernandez (2) | Second | 1½ out |
| Wednesday, April 16 |
| » Lost to White Sox (2-6), 10-4 | Comiskey Park I (1-1) | 4-4 | |
| » W: Floyd Bannister (1-1) L: Walt Terrell (1-1) | Third | 2½ out |
| Thursday, April 17 |
| » Defeated White Sox (2-7), 10-6 | Comiskey Park I (2-1) | 5-4 | |
| » W: Jack Morris (2-1) L: Juan Agosto (0-1) S: Guillermo Hernandez (3) | Second | 1½ out |
| Friday, April 18 |
| » Defeated Indians (4-5), 6-1 | Tiger Stadium (3-1) | 6-4 | Won 2 |
| » W: Frank Tanana (1-1) L: Ken Schrom (2-1) | Second | ½ out |
| » Major-league debuts: Eddie Williams (Indians) |
| Saturday, April 19 |
| » Lost to Indians (5-5), 8-6 | Tiger Stadium (3-2) | 6-5 | |
| » W: Scott Bailes (2-1) L: Dan Petry (1-2) S: Ernie Camacho (3) | Second | ½ out |
| Monday, April 21 |
| » Defeated Red Sox (7-6), 5-4 | Fenway Park (1-0) | 7-5 | |
| » W: Walt Terrell (2-1) L: Al Nipper (1-2) S: Guillermo Hernandez (4) | Second | 1 out |
| Tuesday, April 22 |
| » Lost to Red Sox (8-6), 6-4 | Fenway Park (1-1) | 7-6 | |
| » W: Roger Clemens (3-0) L: Jack Morris (2-2) S: Bob Stanley (1) | Third | 2 out |
| Wednesday, April 23 |
| » Defeated Red Sox (8-7), 3-1 | Fenway Park (2-1) | 8-6 | |
| » W: Frank Tanana (2-1) L: Bruce Hurst (1-2) S: Guillermo Hernandez (5) | Second | 2 out |
| Friday, April 25 |
| » Lost to White Sox (5-10), 9-7 | Tiger Stadium (3-3) | 8-7 | |
| » W: Gene Nelson (1-0) L: Randy O'Neal (0-1) S: Bob James (3) | Second | 3½ out |
| Saturday, April 26 |
| » Lost to White Sox (6-10), 5-4 | Tiger Stadium (3-4) | 8-8 | Lost 2 |
| » W: Bob James (1-1) L: Bill Campbell (0-1) | Third | 3½ out |
| Sunday, April 27 |
| » Defeated White Sox (6-11), 4-1 | Tiger Stadium (4-4) | 9-8 | |
| » W: Jack Morris (3-2) L: Joel Davis (1-1) | Second | 2½ out |
| Tuesday, April 29 |
| » Defeated Royals (8-10), 2-1 | Tiger Stadium (5-4) | 10-8 | Won 2 |
| » W: Frank Tanana (3-1) L: Dennis Leonard (2-2) | Second | 2½ out |
| Wednesday, April 30 |
| » Lost to Royals (9-10), 7-3 | Tiger Stadium (5-5) | 10-9 | |
| » W: Charlie Leibrandt (4-0) L: Guillermo Hernandez (1-1) | Third | 3½ out |
| Thursday, May 1 |
| Former Tiger Ed Wells dies in Montgomery, AL at the age of 86. |
| Friday, May 2 |
| » Lost to Twins (10-13), 10-1 | Tiger Stadium (5-6) | 10-10 | Lost 2 |
| » W: Mike Smithson (3-2) L: Jack Morris (3-3) | Fourth | 3 out |
| Saturday, May 3 |
| » Defeated Twins (10-14), 7-4 | Tiger Stadium (6-6) | 11-10 | |
| » W: Walt Terrell (3-1) L: John Butcher (0-3) | Fourth | 3 out |
| Sunday, May 4 |
| » Defeated Twins (10-15), 4-1 | Tiger Stadium (7-6) | 12-10 | Won 2 |
| » W: Frank Tanana (4-1) L: Bert Blyleven (2-2) S: Guillermo Hernandez (6) | Fourth | 2 out |
| Former Tiger Paul Richards dies in Waxahachie, TX at the age of 78. |
| Monday, May 5 |
| » Defeated Rangers (11-12), 10-3 | Arlington Stadium (1-0) | 13-10 | Won 3 |
| » W: Dan Petry (2-2) L: Jose Guzman (1-5) | Fourth | 2 out |
| Tuesday, May 6 |
| » Lost to Rangers (12-12), 4-2 | Arlington Stadium (1-1) | 13-11 | |
| » W: Charlie Hough (1-0) L: Dave LaPoint (0-1) S: Greg Harris (4) | Fifth | 3 out |
| Wednesday, May 7 |
| » Lost to Rangers (13-12), 2-1 | Arlington Stadium (1-2) | 13-12 | Lost 2 |
| » W: Dwayne Henry (1-0) L: Jack Morris (3-4) S: Greg Harris (5) | Fifth | 4 out |
| Friday, May 9 |
| » Lost to Twins (12-16), 8-7 | Hubert H. Humphrey Metrodome (0-1) | 13-13 | Lost 3 |
| » W: Bert Blyleven (3-2) L: Randy O'Neal (0-2) S: Juan Agosto (1) | Fifth | 4½ out |
| Saturday, May 10 |
| » Lost to Twins (13-16), 12-2 | Hubert H. Humphrey Metrodome (0-2) | 13-14 | Lost 4 |
| » W: Frank Viola (4-2) L: Frank Tanana (4-2) | Fifth | 5½ out |
| Sunday, May 11 |
| » Defeated Twins (13-17), 4-1 | Hubert H. Humphrey Metrodome (1-2) | 14-14 | |
| » W: Dan Petry (3-2) L: Mike Smithson (4-3) | Fifth | 5 out |
| Monday, May 12 |
| » Lost to Royals (13-16), 6-5 | Royals Stadium (0-1) | 14-15 | |
| » W: Danny Jackson (1-0) L: Dave LaPoint (0-2) S: Mark Huismann (1) | Fifth | 5 out |
| Tuesday, May 13 |
| » Lost to Royals (14-16), 4-2 | Royals Stadium (0-2) | 14-16 | Lost 2 |
| » W: Steve Farr (2-0) L: Guillermo Hernandez (1-2) | Sixth | 6 out |
| Wednesday, May 14 |
| » Defeated Rangers (16-15), 8-2 | Tiger Stadium (8-6) | 15-16 | |
| » W: Walt Terrell (4-1) L: Bobby Witt (2-2) | Fifth | 5 out |
| Former Tiger Frank O'Rourke dies in Chatham, NJ at the age of 92. Former Tiger Joe Sparma dies in Columbus, OH at the age of 45. |
| Thursday, May 15 |
| » Lost to Rangers (17-15), 8-1 | Tiger Stadium (8-7) | 15-17 | |
| » W: Mike Mason (3-0) L: Frank Tanana (4-3) | Fifth | 5½ out |
| » Major-league debuts: Eric King (Tigers) |
| Friday, May 16 |
| » Lost to Angels (20-16), 11-1 | Tiger Stadium (8-8) | 15-18 | Lost 2 |
| » W: Mike Witt (3-3) L: Dan Petry (3-3) | Fourth | 5½ out |
| Saturday, May 17 |
| » Defeated Angels (20-17), 10-4 | Tiger Stadium (9-8) | 16-18 | |
| » W: Dave LaPoint (1-2) L: Jim Slaton (4-2) | Fifth | 5½ out |
| Tuesday, May 20 |
| » Defeated Mariners (14-25), 12-0 | Tiger Stadium (10-8) | 17-18 | Won 2 |
| » W: Walt Terrell (5-1) L: Mike Moore (2-5) | Fifth | 6½ out |
| Wednesday, May 21 |
| » Defeated Mariners (14-26), 6-4 | Tiger Stadium (11-8) | 18-18 | Won 3 |
| » W: Eric King (1-0) L: Mark Langston (2-4) | Sixth | 6½ out |
| Thursday, May 22 |
| » Lost to Mariners (15-26), 5-3 | Tiger Stadium (11-9) | 18-19 | |
| » W: Matt Young (4-3) L: Dan Petry (3-4) S: Pete Ladd (4) | Sixth | 7 out |
| Friday, May 23 |
| » Lost to Athletics (21-21), 5-1 | Tiger Stadium (11-10) | 18-20 | Lost 2 |
| » W: Jose Rijo (2-2) L: Dave LaPoint (1-3) | Sixth | 8 out |
| Saturday, May 24 |
| » Defeated Athletics (21-22), 4-1 | Tiger Stadium (12-10) | 19-20 | |
| » W: Jack Morris (4-4) L: Chris Codiroli (3-5) | Sixth | 7 out |
| Sunday, May 25 |
| » Defeated Athletics (21-23), 2-1 | Tiger Stadium (13-10) | 20-20 | Won 2 |
| » W: Walt Terrell (6-1) L: Curt Young (2-1) | Sixth | 7 out |
| Monday, May 26 |
| » Defeated Athletics (21-24), 5-4 | Tiger Stadium (14-10) | 21-20 | Won 3 |
| » W: Guillermo Hernandez (2-2) L: Jay Howell (0-4) | Sixth | 7 out |
| Wednesday, May 28 |
| » Defeated Angels (22-23), 4-1 | Anaheim Stadium (1-0) | 22-20 | Won 4 |
| » W: Dan Petry (4-4) L: Jim Slaton (4-4) S: Eric King (1) | Fourth | 7½ out |
| Thursday, May 29 |
| » Defeated Angels (22-24), 7-4 | Anaheim Stadium (2-0) | 23-20 | Won 5 |
| » W: Dave LaPoint (2-3) L: Don Sutton (2-5) S: Guillermo Hernandez (7) | Fourth | 7 out |
| » Major-league debuts: Chuck Finley (Angels) |
| Friday, May 30 |
| » Lost to Mariners (17-31), 8-7 | Kingdome (0-1) | 23-21 | |
| » W: Mark Huismann (1-2) L: Chuck Cary (0-1) | Fifth | 7 out |
| Saturday, May 31 |
| » Lost to Mariners (18-31), 7-4 | Kingdome (0-2) | 23-22 | Lost 2 |
| » W: Mark Langston (4-4) L: Walt Terrell (6-2) S: Matt Young (2) | Fifth | 8 out |
| Sunday, June 1 |
| » Lost to Mariners (19-31), 9-1 | Kingdome (0-3) | 23-23 | Lost 3 |
| » W: Bill Swift (1-3) L: Frank Tanana (4-4) S: Mark Huismann (2) | Fifth | 9 out |
| Monday, June 2 |
| » Lost to Athletics (24-27), 7-1 | Oakland-Alameda County Stadium (0-1) | 23-24 | Lost 4 |
| » W: Chris Codiroli (4-6) L: Dan Petry (4-5) | Sixth | 10 out |
| Tuesday, June 3 |
| » Lost to Athletics (25-27), 6-4 | Oakland-Alameda County Stadium (0-2) | 23-25 | Lost 5 |
| » W: Curt Young (4-1) L: Dave LaPoint (2-4) S: Jose Rijo (1) | Seventh | 11 out |
| Wednesday, June 4 |
| » Defeated Athletics (25-28), 8-5 | Oakland-Alameda County Stadium (1-2) | 24-25 | |
| » W: Jack Morris (5-4) L: Eric Plunk (0-2) S: Guillermo Hernandez (8) | Fifth | 11 out |
| Friday, June 6 |
| » Lost to Blue Jays (26-28), 12-2 | Tiger Stadium (14-11) | 24-26 | |
| » W: Doyle Alexander (4-2) L: Walt Terrell (6-3) | Seventh | 11½ out |
| Saturday, June 7 |
| » Defeated Blue Jays (26-29), 2-1 | Tiger Stadium (15-11) | 25-26 | |
| » W: Frank Tanana (5-4) L: Jimmy Key (3-5) S: Guillermo Hernandez (9) | Fifth | 10½ out |
| Sunday, June 8 |
| » Lost to Blue Jays (27-29), 4-2 | Tiger Stadium (15-12) | 25-27 | |
| » W: Mark Eichhorn (6-2) L: Randy O'Neal (0-3) S: Tom Henke (7) | Sixth | 10½ out |
| Monday, June 9 |
| » Lost to Yankees (33-23), 9-7 | Tiger Stadium (15-13) | 25-28 | Lost 2 |
| » W: Ed Whitson (5-2) L: Bill Scherrer (0-1) S: Bob Shirley (1) | Seventh | 10½ out |
| Tuesday, June 10 |
| » Lost to Yankees (34-23), 6-3 | Tiger Stadium (15-14) | 25-29 | Lost 3 |
| » W: Joe Niekro (7-3) L: Walt Terrell (6-4) S: Dave Righetti (13) | Seventh | 11½ out |
| Wednesday, June 11 |
| » Defeated Yankees (34-24), 9-3 | Tiger Stadium (16-14) | 26-29 | |
| » W: Frank Tanana (6-4) L: Ron Guidry (4-6) S: Guillermo Hernandez (10) | Seventh | 11½ out |
| Thursday, June 12 |
| » Lost to Blue Jays (29-31), 9-0 | Exhibition Stadium (0-1) | 26-30 | |
| » W: Jimmy Key (4-5) L: Dave LaPoint (2-5) | Seventh | 12 out |
| Friday, June 13 |
| » Defeated Blue Jays (29-32), 10-5 | Exhibition Stadium (1-1) | 27-30 | |
| » W: Eric King (2-0) L: Jim Clancy (6-4) | Sixth | 12 out |
| Saturday, June 14 |
| » Lost to Blue Jays (30-32), 6-5 | Exhibition Stadium (1-2) | 27-31 | |
| » W: Tom Henke (5-3) L: Guillermo Hernandez (2-3) | Seventh | 12 out |
| Sunday, June 15 |
| » Lost to Blue Jays (31-32), 9-6 | Exhibition Stadium (1-3) | 27-32 | Lost 2 |
| » W: Dennis Lamp (2-3) L: Chuck Cary (0-2) S: Tom Henke (8) | Seventh | 12 out |
| Monday, June 16 |
| » Defeated Orioles (35-26), 5-4 | Memorial Stadium (1-0) | 28-32 | |
| » W: Frank Tanana (7-4) L: Ken Dixon (6-4) S: John Pacella (1) | Seventh | 12 out |
| Tuesday, June 17 |
| » Defeated Orioles (35-27), 6-3 | Memorial Stadium (2-0) | 29-32 | Won 2 |
| » W: Randy O'Neal (1-3) L: Storm Davis (5-7) S: Guillermo Hernandez (11) | Seventh | 12 out |
| Wednesday, June 18 |
| » Defeated Orioles (35-28), 6-1 | Memorial Stadium (3-0) | 30-32 | Won 3 |
| » W: Eric King (3-0) L: Scott McGregor (5-7) | Seventh | 12 out |
| Thursday, June 19 |
| » Defeated Orioles (35-29), 7-5 | Memorial Stadium (4-0) | 31-32 | Won 4 |
| » W: Jack Morris (6-4) L: Don Aase (2-3) S: Guillermo Hernandez (12) | Seventh | 11½ out |
| Friday, June 20 |
| » Lost to Brewers (34-30), 1-0 | County Stadium (0-1) | 31-33 | |
| » W: Tim Leary (6-5) L: Walt Terrell (6-5) | Seventh | 11½ out |
| Saturday, June 21 |
| » Defeated Brewers (34-31), 4-3 | County Stadium (1-1) | 32-33 | |
| » W: Bill Campbell (1-1) L: Mark Clear (2-3) S: Guillermo Hernandez (13) | Seventh | 11½ out |
| Sunday, June 22 |
| » Lost to Brewers (35-31), 5-4 | County Stadium (1-2) | 32-34 | |
| » W: Bob Gibson (1-0) L: Dave LaPoint (2-6) | Seventh | 11½ out |
| Tuesday, June 24 |
| » Lost to Orioles (38-30), 2-1 | Tiger Stadium (16-15) | 32-35 | Lost 2 |
| » W: Don Aase (3-3) L: Bill Campbell (1-2) | Seventh | 11 out |
| Wednesday, June 25 |
| » Defeated Orioles (38-31), 11-2 | Tiger Stadium (17-15) | 33-35 | |
| » W: Jack Morris (7-4) L: Mike Boddicker (10-2) | Seventh | 11 out |
| Thursday, June 26 |
| » Defeated Orioles (38-32), 8-3 | Tiger Stadium (18-15) | 34-35 | Won 2 |
| » W: Walt Terrell (7-5) L: Mike Flanagan (1-5) S: Guillermo Hernandez (14) | Seventh | 10½ out |
| Friday, June 27 |
| » Defeated Brewers (36-34), 4-2 | Tiger Stadium (19-15) | 35-35 | Won 3 |
| » W: Guillermo Hernandez (3-3) L: Dan Plesac (4-5) | Sixth | 10½ out |
| Saturday, June 28 |
| » Defeated Brewers (36-35), 8-5 | Tiger Stadium (20-15) | 36-35 | Won 4 |
| » W: Bill Campbell (2-2) L: Bob Gibson (1-1) | Fifth | 10½ out |
| Sunday, June 29 |
| » Defeated Brewers (36-36), 9-5 | Tiger Stadium (21-15) | 37-35 | Won 5 |
| » W: Eric King (4-0) L: Danny Darwin (4-4) S: Guillermo Hernandez (15) | Sixth | 11 out |
| » Lost to Brewers (37-36), 3-1 | Tiger Stadium (21-16) | 37-36 | |
| » W: Teddy Higuera (10-6) L: Jack Morris (7-5) S: Dan Plesac (7) | Sixth | 11 out |
| Monday, June 30 |
| » Lost to Yankees (42-34), 3-2 | Yankee Stadium (0-1) | 37-37 | Lost 2 |
| » W: Dennis Rasmussen (8-2) L: Walt Terrell (7-6) S: Dave Righetti (17) | Sixth | 12 out |
| Tuesday, July 1 |
| » Lost to Yankees (43-34), 5-4 | Yankee Stadium (0-2) | 37-38 | Lost 3 |
| » W: Dave Righetti (6-4) L: Guillermo Hernandez (3-4) | Sixth | 13 out |
| Wednesday, July 2 |
| » Defeated Yankees (43-35), 8-3 | Yankee Stadium (1-2) | 38-38 | |
| » W: Dave LaPoint (3-6) L: Ron Guidry (4-8) S: Guillermo Hernandez (16) | Sixth | 12 out |
| Thursday, July 3 |
| » Lost to Yankees (44-35), 9-5 | Yankee Stadium (1-3) | 38-39 | |
| » W: Alfonso Pulido (1-0) L: Eric King (4-1) S: Dave Righetti (18) | Seventh | 12 out |
| Friday, July 4 |
| » Lost to Rangers (43-36), 2-1 | Arlington Stadium (1-3) | 38-40 | Lost 2 |
| » W: Jose Guzman (8-8) L: Jack Morris (7-6) S: Greg Harris (15) | Seventh | 13 out |
| Saturday, July 5 |
| » Lost to Rangers (44-36), 9-3 | Arlington Stadium (1-4) | 38-41 | Lost 3 |
| » W: Ed Correa (6-6) L: Walt Terrell (7-7) | Seventh | 13 out |
| Sunday, July 6 |
| » Defeated Rangers (44-37), 5-2 | Arlington Stadium (2-4) | 39-41 | |
| » W: Frank Tanana (8-4) L: Bobby Witt (4-7) S: Guillermo Hernandez (17) | Seventh | 13 out |
| Monday, July 7 |
| » Lost to Twins (36-46), 10-8 | Hubert H. Humphrey Metrodome (1-3) | 39-42 | |
| » W: Mike Smithson (8-7) L: Randy O'Neal (1-4) S: Keith Atherton (6) | Seventh | 13 out |
| Tuesday, July 8 |
| » Defeated Twins (36-47), 5-1 | Hubert H. Humphrey Metrodome (2-3) | 40-42 | |
| » W: Eric King (5-1) L: Bert Blyleven (7-8) S: Guillermo Hernandez (18) | Seventh | 13 out |
| Former Tiger Skeeter Webb dies in Meridian, MS at the age of 77. |
| Wednesday, July 9 |
| » Defeated Twins (36-48), 7-0 | Hubert H. Humphrey Metrodome (3-3) | 41-42 | Won 2 |
| » W: Jack Morris (8-6) L: Allan Anderson (2-2) | Sixth | 13 out |
| Friday, July 11 |
| » Lost to Royals (39-46), 4-3 | Royals Stadium (0-3) | 41-43 | |
| » W: Steve Farr (6-1) L: Walt Terrell (7-8) | Sixth | 13 out |
| » Defeated Royals (39-47), 8-7 | Royals Stadium (1-3) | 42-43 | |
| » W: Guillermo Hernandez (4-4) L: Mark Gubicza (3-5) S: Bill Campbell (1) | Sixth | 13 out |
| Saturday, July 12 |
| » Lost to Royals (40-47), 7-4 | Royals Stadium (1-4) | 42-44 | |
| » W: Charlie Leibrandt (9-6) L: Eric King (5-2) S: Danny Jackson (1) | Sixth | 14 out |
| Sunday, July 13 |
| » Defeated Royals (40-48), 5-0 | Royals Stadium (2-4) | 43-44 | |
| » W: Jack Morris (9-6) L: Scott Bankhead (3-3) | Sixth | 13 out |
| Thursday, July 17 |
| » Defeated Rangers (47-42), 2-1 | Tiger Stadium (22-16) | 44-44 | Won 2 |
| » W: Walt Terrell (8-8) L: Mitch Williams (7-2) | Sixth | 12 out |
| Friday, July 18 |
| » Defeated Rangers (47-43), 5-0 | Tiger Stadium (23-16) | 45-44 | Won 3 |
| » W: Jack Morris (10-6) L: Mike Mason (6-3) | Sixth | 11 out |
| Saturday, July 19 |
| » Defeated Rangers (47-44), 5-3 | Tiger Stadium (24-16) | 46-44 | Won 4 |
| » W: Guillermo Hernandez (5-4) L: Greg Harris (3-8) | Sixth | 11 out |
| Sunday, July 20 |
| » Defeated Rangers (47-45), 4-0 | Tiger Stadium (25-16) | 47-44 | Won 5 |
| » W: Eric King (6-2) L: Jose Guzman (8-10) | Sixth | 10 out |
| Monday, July 21 |
| » Lost to Twins (39-54), 1-0 | Tiger Stadium (25-17) | 47-45 | |
| » W: Frank Viola (10-8) L: Mark Thurmond (3-8) S: Keith Atherton (8) | Sixth | 10 out |
| Tuesday, July 22 |
| » Defeated Twins (39-55), 3-0 | Tiger Stadium (26-17) | 48-45 | |
| » W: Walt Terrell (9-8) L: Bert Blyleven (9-9) S: Guillermo Hernandez (19) | Sixth | 9 out |
| Wednesday, July 23 |
| » Defeated Twins (39-56), 12-2 | Tiger Stadium (27-17) | 49-45 | Won 2 |
| » W: Jack Morris (11-6) L: Allan Anderson (2-3) | Sixth | 8 out |
| Thursday, July 24 |
| » Lost to Royals (45-51), 1-0 | Tiger Stadium (27-18) | 49-46 | |
| » W: Scott Bankhead (4-4) L: Randy O'Neal (1-5) S: Dan Quisenberry (9) | Sixth | 8½ out |
| Friday, July 25 |
| » Defeated Royals (45-52), 9-2 | Tiger Stadium (28-18) | 50-46 | |
| » W: Eric King (7-2) L: Dennis Leonard (6-9) | Sixth | 8½ out |
| Saturday, July 26 |
| » Defeated Royals (45-53), 4-3 | Tiger Stadium (29-18) | 51-46 | Won 2 |
| » W: Guillermo Hernandez (6-4) L: Steve Farr (7-2) | Fifth | 7½ out |
| Sunday, July 27 |
| » Lost to Royals (46-53), 5-4 | Tiger Stadium (29-19) | 51-47 | |
| » W: Bret Saberhagen (6-10) L: Guillermo Hernandez (6-5) | Sixth | 7½ out |
| Monday, July 28 |
| » Defeated Indians (52-45), 5-1 | Cleveland Stadium (2-2) | 52-47 | |
| » W: Jack Morris (12-6) L: Ken Schrom (11-3) | Sixth | 7½ out |
| Tuesday, July 29 |
| » Defeated Indians (52-46), 6-3 | Cleveland Stadium (3-2) | 53-47 | Won 2 |
| » W: Guillermo Hernandez (7-5) L: Bryan Oelkers (1-2) S: Jim Slaton (1) | Fifth | 6½ out |
| Wednesday, July 30 |
| » Defeated Indians (52-47), 11-3 | Cleveland Stadium (4-2) | 54-47 | Won 3 |
| » W: Eric King (8-2) L: John Butcher (1-7) | Fourth | 5½ out |
| Thursday, July 31 |
| » Lost to Indians (53-47), 8-7 | Cleveland Stadium (4-3) | 54-48 | |
| » W: Scott Bailes (8-6) L: Bill Campbell (2-3) | Sixth | 6 out |
| Friday, August 1 |
| » Defeated White Sox (44-57), 5-4 | Comiskey Park I (3-1) | 55-48 | |
| » W: Walt Terrell (10-8) L: Richard Dotson (7-12) S: Guillermo Hernandez (20) | Fourth | 6 out |
| Saturday, August 2 |
| » Lost to White Sox (45-57), 5-3 | Comiskey Park I (3-2) | 55-49 | |
| » W: Floyd Bannister (6-8) L: Jack Morris (12-7) | Fifth | 6 out |
| Sunday, August 3 |
| » Lost to White Sox (46-57), 10-1 | Comiskey Park I (3-3) | 55-50 | Lost 2 |
| » W: Joe Cowley (7-6) L: Randy O'Neal (1-6) | Sixth | 7 out |
| » Major-league debuts: Russ Morman (White Sox) |
| Tuesday, August 5 |
| » Defeated Indians (55-50), 6-5 | Tiger Stadium (30-19) | 56-50 | |
| » W: Mark Thurmond (4-8) L: Scott Bailes (8-7) S: Bill Campbell (2) | Fourth | 5 out |
| » Defeated Indians (55-51), 11-9 | Tiger Stadium (31-19) | 57-50 | Won 2 |
| » W: Frank Tanana (9-4) L: John Butcher (1-8) S: Randy O'Neal (1) | Fourth | 5 out |
| Thursday, August 7 |
| » Defeated Indians (55-52), 15-1 | Tiger Stadium (32-19) | 58-50 | Won 3 |
| » W: Jack Morris (13-7) L: Phil Niekro (8-9) | Third | 4½ out |
| » Defeated Indians (55-53), 6-2 | Tiger Stadium (33-19) | 59-50 | Won 4 |
| » W: Mark Thurmond (5-8) L: Ken Schrom (11-4) S: Bill Campbell (3) | Third | 4½ out |
| Friday, August 8 |
| » Lost to Red Sox (63-44), 6-1 | Tiger Stadium (33-20) | 59-51 | |
| » W: Tom Seaver (5-10) L: Randy O'Neal (1-7) | Fourth | 5½ out |
| Saturday, August 9 |
| » Lost to Red Sox (64-44), 8-7 | Tiger Stadium (33-21) | 59-52 | Lost 2 |
| » W: Al Nipper (7-7) L: Frank Tanana (9-5) S: Calvin Schiraldi (2) | Fourth | 6½ out |
| Sunday, August 10 |
| » Lost to Red Sox (65-44), 9-6 | Tiger Stadium (33-22) | 59-53 | Lost 3 |
| » W: Joe Sambito (2-0) L: Bill Campbell (2-4) S: Calvin Schiraldi (3) | Fourth | 7½ out |
| Monday, August 11 |
| » Defeated Red Sox (65-45), 5-0 | Tiger Stadium (34-22) | 60-53 | |
| » W: Jack Morris (14-7) L: Oil Can Boyd (11-8) | Fourth | 6½ out |
| Tuesday, August 12 |
| » Defeated White Sox (50-61), 7-3 | Tiger Stadium (35-22) | 61-53 | Won 2 |
| » W: Mark Thurmond (6-8) L: Steve Carlton (5-12) | Third | 5 out |
| Wednesday, August 13 |
| » Defeated White Sox (50-62), 5-2 | Tiger Stadium (36-22) | 62-53 | Won 3 |
| » W: Randy O'Neal (2-7) L: Joe Cowley (8-7) | Third | 5 out |
| Thursday, August 14 |
| » Lost to White Sox (51-62), 8-2 | Tiger Stadium (36-23) | 62-54 | |
| » W: Jose DeLeon (4-4) L: Frank Tanana (9-6) | Fourth | 6 out |
| Friday, August 15 |
| » Lost to Red Sox (68-47), 8-5 | Fenway Park (2-2) | 62-55 | Lost 2 |
| » W: Roger Clemens (18-4) L: Walt Terrell (10-9) S: Joe Sambito (11) | Fourth | 7 out |
| Saturday, August 16 |
| » Defeated Red Sox (68-48), 12-6 | Fenway Park (3-2) | 63-55 | |
| » W: Jack Morris (15-7) L: Oil Can Boyd (11-9) | Third | 6 out |
| Sunday, August 17 |
| » Lost to Red Sox (69-48), 7-5 | Fenway Park (3-3) | 63-56 | |
| » W: Calvin Schiraldi (1-0) L: Eric King (8-3) | Third | 7 out |
| Tuesday, August 19 |
| » Lost to Angels (66-52), 5-2 | Tiger Stadium (36-24) | 63-57 | Lost 2 |
| » W: Kirk McCaskill (13-7) L: Dan Petry (4-6) S: Donnie Moore (15) | Fourth | 7 out |
| » Defeated Angels (66-53), 8-3 | Tiger Stadium (37-24) | 64-57 | |
| » W: Randy O'Neal (3-7) L: Vern Ruhle (1-2) | Fourth | 7 out |
| Wednesday, August 20 |
| » Defeated Angels (66-54), 3-0 | Tiger Stadium (38-24) | 65-57 | Won 2 |
| » W: Walt Terrell (11-9) L: John Candelaria (6-2) | Fourth | 7 out |
| Thursday, August 21 |
| » Lost to Angels (67-54), 6-1 | Tiger Stadium (38-25) | 65-58 | |
| » W: Mike Witt (15-7) L: Jack Morris (15-8) | Fourth | 8 out |
| Friday, August 22 |
| » Defeated Mariners (53-70), 4-1 | Tiger Stadium (39-25) | 66-58 | |
| » W: Eric King (9-3) L: Mike Morgan (9-13) | Third | 8 out |
| Saturday, August 23 |
| » Defeated Mariners (53-71), 14-0 | Tiger Stadium (40-25) | 67-58 | Won 2 |
| » W: Frank Tanana (10-6) L: Mike Brown (4-5) | Third | 7 out |
| Sunday, August 24 |
| » Lost to Mariners (54-71), 3-1 | Tiger Stadium (40-26) | 67-59 | |
| » W: Mark Langston (11-10) L: Dan Petry (4-7) S: Matt Young (11) | Fourth | 7 out |
| Monday, August 25 |
| » Lost to Athletics (56-69), 8-4 | Tiger Stadium (40-27) | 67-60 | Lost 2 |
| » W: Jose Rijo (6-9) L: Walt Terrell (11-10) | Third | 7 out |
| Tuesday, August 26 |
| » Defeated Athletics (56-70), 8-7 | Tiger Stadium (41-27) | 68-60 | |
| » W: Mark Thurmond (7-8) L: Dave Von Ohlen (0-1) S: Guillermo Hernandez (21) | Fourth | 7 out |
| Thursday, August 28 |
| » Lost to Angels (71-56), 4-2 | Anaheim Stadium (2-1) | 68-61 | |
| » W: Don Sutton (12-9) L: Eric King (9-4) S: Donnie Moore (18) | Fourth | 7 out |
| Friday, August 29 |
| » Lost to Angels (72-56), 13-12 | Anaheim Stadium (2-2) | 68-62 | Lost 2 |
| » W: Doug Corbett (3-2) L: Guillermo Hernandez (7-6) | Fourth | 7 out |
| Saturday, August 30 |
| » Lost to Angels (73-56), 5-4 | Anaheim Stadium (2-3) | 68-63 | Lost 3 |
| » W: Gary Lucas (2-0) L: Bill Campbell (2-5) | Fourth | 8 out |
| Sunday, August 31 |
| » Lost to Angels (74-56), 5-3 | Anaheim Stadium (2-4) | 68-64 | Lost 4 |
| » W: Donnie Moore (3-5) L: Walt Terrell (11-11) | Fourth | 9 out |
| Monday, September 1 |
| » Defeated Mariners (58-75), 6-5 | Kingdome (1-3) | 69-64 | |
| » W: Jack Morris (16-8) L: Mike Morgan (9-15) | Fourth | 9 out |
| Tuesday, September 2 |
| » Defeated Mariners (58-76), 7-5 | Kingdome (2-3) | 70-64 | Won 2 |
| » W: Bill Campbell (3-5) L: Lee Guetterman (0-4) S: Jim Slaton (2) | Fourth | 9 out |
| Wednesday, September 3 |
| » Lost to Mariners (59-76), 3-2 | Kingdome (2-4) | 70-65 | |
| » W: Mike Trujillo (2-0) L: Bryan Kelly (0-1) | Fourth | 10 out |
| Thursday, September 4 |
| Former Tiger Hank Greenberg dies in Beverly Hills, CA at the age of 76. |
| Friday, September 5 |
| » Defeated Athletics (63-73), 9-4 | Oakland-Alameda County Stadium (2-2) | 71-65 | |
| » W: Chuck Cary (1-2) L: Dave Von Ohlen (0-2) S: Mark Thurmond (1) | Fourth | 10 out |
| Saturday, September 6 |
| » Lost to Athletics (64-73), 5-4 | Oakland-Alameda County Stadium (2-3) | 71-66 | |
| » W: Joaquin Andujar (9-6) L: Bill Campbell (3-6) | Fourth | 11 out |
| Sunday, September 7 |
| » Lost to Athletics (65-73), 8-4 | Oakland-Alameda County Stadium (2-4) | 71-67 | Lost 2 |
| » W: Curt Young (11-8) L: Dan Petry (4-8) S: Bill Mooneyham (2) | Fourth | 12 out |
| Tuesday, September 9 |
| » Lost to Brewers (66-71), 3-1 | Tiger Stadium (41-28) | 71-68 | Lost 3 |
| » W: Teddy Higuera (18-9) L: Frank Tanana (10-7) S: Dan Plesac (12) | Fourth | 13½ out |
| Wednesday, September 10 |
| » Defeated Brewers (66-72), 11-7 | Tiger Stadium (42-28) | 72-68 | |
| » W: Walt Terrell (12-11) L: Chris Bosio (0-4) S: Mark Thurmond (2) | Fourth | 13½ out |
| Thursday, September 11 |
| » Defeated Brewers (66-73), 8-0 | Tiger Stadium (43-28) | 73-68 | Won 2 |
| » W: Jack Morris (17-8) L: Juan Nieves (10-10) | Fourth | 12½ out |
| Friday, September 12 |
| » Defeated Orioles (68-73), 5-3 | Tiger Stadium (44-28) | 74-68 | Won 3 |
| » W: Eric King (10-4) L: Scott McGregor (10-12) | Fourth | 12½ out |
| Saturday, September 13 |
| » Defeated Orioles (68-74), 7-2 | Tiger Stadium (45-28) | 75-68 | Won 4 |
| » W: Guillermo Hernandez (8-6) L: Mike Flanagan (7-10) | Fourth | 11½ out |
| Sunday, September 14 |
| » Defeated Orioles (68-75), 7-0 | Tiger Stadium (46-28) | 76-68 | Won 5 |
| » W: Frank Tanana (11-7) L: John Habyan (0-2) | Third | 10½ out |
| » Major-league debuts: Ken Gerhart (Orioles) |
| Tuesday, September 16 |
| » Lost to Blue Jays (79-66), 6-4 | Exhibition Stadium (1-4) | 76-69 | |
| » W: Jimmy Key (13-10) L: Walt Terrell (12-12) S: Tom Henke (22) | Third | 12 out |
| Wednesday, September 17 |
| » Defeated Blue Jays (79-67), 8-6 | Exhibition Stadium (2-4) | 77-69 | |
| » W: Jack Morris (18-8) L: Jim Clancy (14-11) S: Guillermo Hernandez (22) | Third | 12 out |
| Friday, September 19 |
| » Defeated Yankees (79-68), 8-3 | Tiger Stadium (47-28) | 78-69 | Won 2 |
| » W: Dan Petry (5-8) L: Dennis Rasmussen (15-6) S: Eric King (2) | Fourth | 11½ out |
| Saturday, September 20 |
| » Lost to Yankees (80-68), 5-2 | Tiger Stadium (47-29) | 78-70 | |
| » W: Ron Guidry (9-10) L: Frank Tanana (11-8) | Fourth | |