| Wednesday, January 1 |
| Former Pirate Bill Hall dies in Moultrie, GA at the age of 58. |
| Sunday, January 12 |
| Former Pirate Eddie Solomon dies in Macon, GA at the age of 35. |
| Tuesday, February 25 |
| Former Pirate George Susce dies in Sarasota, FL at the age of 79. |
| Monday, April 7 |
| » Major-league debuts: John Kruk (Padres) |
| Tuesday, April 8 |
| » Lost to Mets (1-0), 4-2 | Three Rivers Stadium (0-1) | 0-1 | |
| » W: Dwight Gooden (1-0) L: Rick Reuschel (0-1) | Second | 1 out |
| Friday, April 11 |
| » Lost to Cubs (1-2), 5-4 | Three Rivers Stadium (0-2) | 0-2 | Lost 2 |
| » W: Steve Trout (1-0) L: Larry McWilliams (0-1) S: Lee Smith (1) | Fourth | 2½ out |
| Saturday, April 12 |
| » Defeated Cubs (1-3), 3-1 | Three Rivers Stadium (1-2) | 1-2 | |
| » W: Rick Rhoden (1-0) L: Lee Smith (0-1) S: Cecilio Guante (1) | Fourth | 2½ out |
| Sunday, April 13 |
| » Defeated Cubs (1-4), 8-0 | Three Rivers Stadium (2-2) | 2-2 | Won 2 |
| » W: Rick Reuschel (1-1) L: Rick Sutcliffe (0-2) | Third | 1½ out |
| Monday, April 14 |
| » Defeated Phillies (3-3), 3-1 | Veteran's Stadium (1-0) | 3-2 | Won 3 |
| » W: Cecilio Guante (1-0) L: Steve Bedrosian (1-1) S: Jim Winn (1) | Second | 1½ out |
| Friday, April 18 |
| » Defeated Cubs (2-6), 4-0 | Wrigley Field (1-0) | 4-2 | Won 4 |
| » W: Rick Rhoden (2-0) L: Rick Sutcliffe (0-3) | Second | 1½ out |
| Saturday, April 19 |
| » Defeated Cubs (2-7), 14-8 | Wrigley Field (2-0) | 5-2 | Won 5 |
| » W: Rick Reuschel (2-1) L: Scott Sanderson (0-1) | Second | 1½ out |
| Monday, April 21 |
| » Lost to Mets (6-3), 6-5 | Shea Stadium (0-1) | 5-3 | |
| » W: Roger McDowell (1-0) L: Pat Clements (0-1) | Third | 1½ out |
| Tuesday, April 22 |
| » Lost to Mets (7-3), 7-1 | Shea Stadium (0-2) | 5-4 | Lost 2 |
| » W: Bob Ojeda (2-0) L: Bob Kipper (0-1) | Second | 1½ out |
| Thursday, April 24 |
| » Lost to Phillies (5-7), 4-2 | Three Rivers Stadium (2-3) | 5-5 | Lost 3 |
| » W: Shane Rawley (2-1) L: Rick Rhoden (2-1) | Third | 2½ out |
| Friday, April 25 |
| » Lost to Phillies (6-7), 6-3 | Three Rivers Stadium (2-4) | 5-6 | Lost 4 |
| » W: Kevin Gross (1-2) L: Rick Reuschel (2-2) S: Steve Bedrosian (2) | Fourth | 3½ out |
| Saturday, April 26 |
| » Lost to Phillies (7-7), 6-5 | Three Rivers Stadium (2-5) | 5-7 | Lost 5 |
| » W: Charles Hudson (2-1) L: Larry McWilliams (0-2) S: Steve Bedrosian (3) | Fourth | 4½ out |
| Sunday, April 27 |
| » Defeated Phillies (7-8), 13-5 | Three Rivers Stadium (3-5) | 6-7 | |
| » W: Mike Bielecki (1-0) L: Steve Carlton (1-3) S: Bob Walk (1) | Third | 4½ out |
| Monday, April 28 |
| » Lost to Dodgers (8-13), 2-1 | Dodger Stadium (0-1) | 6-8 | |
| » W: Fernando Valenzuela (3-1) L: Bob Kipper (0-2) | Fifth | 5 out |
| Tuesday, April 29 |
| » Lost to Dodgers (9-13), 5-4 | Dodger Stadium (0-2) | 6-9 | Lost 2 |
| » W: Orel Hershiser (3-2) L: Bob Patterson (0-1) S: Ken Howell (1) | Fifth | 6 out |
| Wednesday, April 30 |
| » Lost to Giants (13-8), 6-5 | Candlestick Park (0-1) | 6-10 | Lost 3 |
| » W: Scott Garrelts (3-2) L: Bob Patterson (0-2) | Sixth | 7 out |
| Thursday, May 1 |
| » Defeated Giants (13-9), 6-2 | Candlestick Park (1-1) | 7-10 | |
| » W: Bob Walk (1-0) L: Mike Krukow (3-2) | Fifth | 6 out |
| Friday, May 2 |
| » Defeated Padres (13-10), 4-0 | San Diego/Jack Murphy Stadium (1-0) | 8-10 | Won 2 |
| » W: Mike Bielecki (2-0) L: Dave Dravecky (2-2) S: Jim Winn (2) | Third | 6 out |
| Saturday, May 3 |
| » Defeated Padres (13-11), 7-6 | San Diego/Jack Murphy Stadium (2-0) | 9-10 | Won 3 |
| » W: Cecilio Guante (2-0) L: Rich Gossage (2-2) S: Pat Clements (1) | Third | 6 out |
| Sunday, May 4 |
| » Defeated Padres (13-12), 5-2 | San Diego/Jack Murphy Stadium (3-0) | 10-10 | Won 4 |
| » W: Jim Winn (1-0) L: Craig Lefferts (3-1) | Third | 6 out |
| Tuesday, May 6 |
| » Lost to Giants (16-11), 7-2 | Three Rivers Stadium (3-6) | 10-11 | |
| » W: Mike Krukow (4-2) L: Rick Reuschel (2-3) | Third | 7 out |
| Wednesday, May 7 |
| » Lost to Giants (17-11), 7-5 | Three Rivers Stadium (3-7) | 10-12 | Lost 2 |
| » W: Bill Laskey (1-0) L: Larry McWilliams (0-3) S: Jeff Robinson (3) | Third | 8 out |
| Thursday, May 8 |
| » Defeated Giants (17-12), 8-2 | Three Rivers Stadium (4-7) | 11-12 | |
| » W: Mike Bielecki (3-0) L: Scott Garrelts (3-3) | Third | 7½ out |
| Friday, May 9 |
| » Lost to Astros (16-10), 3-2 | Three Rivers Stadium (4-8) | 11-13 | |
| » W: Charlie Kerfeld (3-0) L: Jim Winn (1-1) S: Dave Smith (9) | Third | 8½ out |
| Saturday, May 10 |
| » Lost to Astros (17-10), 6-3 | Three Rivers Stadium (4-9) | 11-14 | Lost 2 |
| » W: Bob Knepper (6-1) L: Rick Rhoden (2-2) S: Frank DiPino (1) | Fourth | 9½ out |
| Sunday, May 11 |
| » Defeated Astros (17-11), 4-3 | Three Rivers Stadium (5-9) | 12-14 | |
| » W: Jose DeLeon (1-0) L: Charlie Kerfeld (3-1) | Fourth | 8½ out |
| Tuesday, May 13 |
| » Lost to Padres (16-16), 4-2 | Three Rivers Stadium (5-10) | 12-15 | |
| » W: Eric Show (2-2) L: Mike Bielecki (3-1) S: Lance McCullers (1) | Fourth | 9 out |
| Wednesday, May 14 |
| » Lost to Padres (17-16), 10-4 | Three Rivers Stadium (5-11) | 12-16 | Lost 2 |
| » W: Dave Dravecky (3-3) L: Bob Kipper (0-3) S: Rich Gossage (6) | Fifth | 9 out |
| Friday, May 16 |
| » Lost to Reds (10-21), 7-2 | Riverfront Stadium (0-1) | 12-17 | Lost 3 |
| » W: John Denny (2-4) L: Rick Rhoden (2-3) S: John Franco (5) | Fifth | 9½ out |
| Saturday, May 17 |
| » Defeated Reds (10-22), 4-0 | Riverfront Stadium (1-1) | 13-17 | |
| » W: Rick Reuschel (3-3) L: Mario Soto (2-6) | Fourth | 8½ out |
| Sunday, May 18 |
| » Lost to Reds (11-22), 7-3 | Riverfront Stadium (1-2) | 13-18 | |
| » W: Tom Browning (1-4) L: Mike Bielecki (3-2) S: Ron Robinson (2) | Fourth | 9½ out |
| Tuesday, May 20 |
| » Defeated Astros (21-15), 4-2 | Astrodome (1-0) | 14-18 | |
| » W: Bob Walk (2-0) L: Nolan Ryan (3-6) | Third | 9½ out |
| Wednesday, May 21 |
| » Defeated Astros (21-16), 2-1 | Astrodome (2-0) | 15-18 | Won 2 |
| » W: Rick Rhoden (3-3) L: Mike Scott (4-3) | Third | 9½ out |
| Thursday, May 22 |
| » Lost to Astros (22-16), 4-0 | Astrodome (2-1) | 15-19 | |
| » W: Bob Knepper (8-2) L: Rick Reuschel (3-4) | Third | 9½ out |
| Friday, May 23 |
| » Lost to Reds (14-23), 12-9 | Three Rivers Stadium (5-12) | 15-20 | Lost 2 |
| » W: Ted Power (2-3) L: Jose DeLeon (1-1) | Third | 9½ out |
| Saturday, May 24 |
| » Lost to Reds (15-23), 4-2 | Three Rivers Stadium (5-13) | 15-21 | Lost 3 |
| » W: Bill Gullickson (4-3) L: Mike Bielecki (3-3) | Fourth | 10½ out |
| Sunday, May 25 |
| » Lost to Reds (16-23), 7-4 | Three Rivers Stadium (5-14) | 15-22 | Lost 4 |
| » W: John Denny (3-5) L: Bob Kipper (0-4) | Fourth | 11½ out |
| Monday, May 26 |
| » Lost to Braves (23-20), 9-4 | Three Rivers Stadium (5-15) | 15-23 | Lost 5 |
| » W: Paul Assenmacher (2-1) L: Bob Walk (2-1) | Fifth | 12 out |
| Tuesday, May 27 |
| » Lost to Braves (24-20), 6-2 | Three Rivers Stadium (5-16) | 15-24 | Lost 6 |
| » W: Gene Garber (1-1) L: Bob Walk (2-2) | Sixth | 13 out |
| Wednesday, May 28 |
| » Defeated Braves (24-21), 4-3 | Three Rivers Stadium (6-16) | 16-24 | |
| » W: Larry McWilliams (1-3) L: David Palmer (3-4) S: Jose DeLeon (1) | Fifth | 13 out |
| Friday, May 30 |
| » Lost to Dodgers (23-25), 6-4 | Three Rivers Stadium (6-17) | 16-25 | |
| » W: Tom Niedenfuer (3-2) L: Jose DeLeon (1-2) S: Jerry Reuss (1) | Fifth | 14½ out |
| » Major-league debuts: Barry Bonds (Pirates) |
| Saturday, May 31 |
| » Defeated Dodgers (23-26), 4-0 | Three Rivers Stadium (7-17) | 17-25 | |
| » W: Bob Kipper (1-4) L: Rick Honeycutt (2-3) S: Pat Clements (2) | Fifth | 13½ out |
| Sunday, June 1 |
| » Defeated Dodgers (23-27), 12-3 | Three Rivers Stadium (8-17) | 18-25 | Won 2 |
| » W: Rick Rhoden (4-3) L: Bob Welch (3-5) | Fifth | 12½ out |
| Monday, June 2 |
| » Defeated Braves (25-24), 9-2 | Atlanta-Fulton County Stadium (1-0) | 19-25 | Won 3 |
| » W: Rick Reuschel (4-4) L: David Palmer (3-5) | Fifth | 12½ out |
| » Major-league debuts: Ed Olwine (Braves) |
| Tuesday, June 3 |
| » Lost to Braves (26-24), 8-5 | Atlanta-Fulton County Stadium (1-1) | 19-26 | |
| » W: Rick Mahler (5-5) L: Cecilio Guante (2-1) S: Paul Assenmacher (5) | Sixth | 12½ out |
| Wednesday, June 4 |
| » Defeated Braves (26-25), 12-3 | Atlanta-Fulton County Stadium (2-1) | 20-26 | |
| » W: Mike Bielecki (4-3) L: Joe Johnson (6-4) S: Jim Winn (3) | Fourth | 12½ out |
| Thursday, June 5 |
| » Lost to Mets (34-14), 7-0 | Three Rivers Stadium (8-18) | 20-27 | |
| » W: Bob Ojeda (7-2) L: Bob Kipper (1-5) | Fifth | 13½ out |
| Friday, June 6 |
| » Defeated Mets (34-15), 7-1 | Three Rivers Stadium (9-18) | 21-27 | |
| » W: Rick Rhoden (5-3) L: Ron Darling (6-2) S: Bob Walk (2) | Fifth | 13½ out |
| » Lost to Mets (35-15), 10-4 | Three Rivers Stadium (9-19) | 21-28 | |
| » W: Roger McDowell (5-0) L: Jose DeLeon (1-3) | Fifth | 13½ out |
| Saturday, June 7 |
| » Lost to Mets (36-15), 6-4 | Three Rivers Stadium (9-20) | 21-29 | Lost 2 |
| » W: Dwight Gooden (8-2) L: Rick Reuschel (4-5) S: Jesse Orosco (9) | Sixth | 14½ out |
| Sunday, June 8 |
| » Lost to Mets (37-15), 4-3 | Three Rivers Stadium (9-21) | 21-30 | Lost 3 |
| » W: Sid Fernandez (6-2) L: Larry McWilliams (1-4) S: Jesse Orosco (10) | Sixth | 15½ out |
| Monday, June 9 |
| » Defeated Cubs (23-31), 6-5 | Three Rivers Stadium (10-21) | 22-30 | |
| » W: Don Robinson (1-0) L: Jay Baller (2-4) | Fifth | 14½ out |
| Tuesday, June 10 |
| » Defeated Cubs (23-32), 6-4 | Three Rivers Stadium (11-21) | 23-30 | Won 2 |
| » W: Bob Kipper (2-5) L: Dennis Eckersley (2-4) S: Cecilio Guante (2) | Fourth | 14½ out |
| Wednesday, June 11 |
| » Defeated Cubs (23-33), 5-3 | Three Rivers Stadium (12-21) | 24-30 | Won 3 |
| » W: Rick Rhoden (6-3) L: Guy Hoffman (2-2) S: Don Robinson (1) | Fourth | 14½ out |
| Friday, June 13 |
| » Lost to Mets (40-16), 6-5 | Shea Stadium (0-3) | 24-31 | |
| » W: Jesse Orosco (3-2) L: Pat Clements (0-2) | Fourth | 15½ out |
| Saturday, June 14 |
| » Lost to Mets (41-16), 5-1 | Shea Stadium (0-4) | 24-32 | Lost 2 |
| » W: Sid Fernandez (7-2) L: Mike Bielecki (4-4) | Fourth | 16½ out |
| Sunday, June 15 |
| » Lost to Mets (42-16), 4-1 | Shea Stadium (0-5) | 24-33 | Lost 3 |
| » W: Bob Ojeda (8-2) L: Bob Walk (2-3) | Fifth | 18½ out |
| » Lost to Mets (43-16), 8-5 | Shea Stadium (0-6) | 24-34 | Lost 4 |
| » W: Rick Aguilera (1-3) L: Bob Kipper (2-6) S: Roger McDowell (5) | Fifth | 18½ out |
| Monday, June 16 |
| » Game at Three Rivers Stadium interrupted in the 6th inning with the score of Cardinals 4, Pirates 1. Completed on June 18. |
| Tuesday, June 17 |
| » Lost to Cardinals (25-35), 7-2 | Three Rivers Stadium (12-22) | 24-35 | Lost 5 |
| » W: Greg Mathews (3-1) L: Rick Reuschel (4-6) | Sixth | 19 out |
| Wednesday, June 18 |
| » Lost to Cardinals (26-35), 4-2 | Three Rivers Stadium (12-23) | 24-36 | Lost 6 |
| » W: Danny Cox (2-5) L: Rick Rhoden (6-4) S: Todd Worrell (12) | Sixth | 18½ out |
| » Defeated Cardinals (26-36), 2-1 | Three Rivers Stadium (13-23) | 25-36 | |
| » W: Don Robinson (2-0) L: Todd Worrell (3-7) | Sixth | 18½ out |
| Thursday, June 19 |
| » Defeated Expos (34-28), 4-2 | Stade Olympique (1-0) | 26-36 | Won 2 |
| » W: Bob Kipper (3-6) L: Bryn Smith (4-5) S: Cecilio Guante (3) | Fifth | 18 out |
| Friday, June 20 |
| » Lost to Expos (35-28), 7-2 | Stade Olympique (1-1) | 26-37 | |
| » W: Andy McGaffigan (5-2) L: Bob Walk (2-4) S: Bob McClure (1) | Fifth | 19 out |
| Saturday, June 21 |
| » Defeated Expos (35-29), 14-1 | Stade Olympique (2-1) | 27-37 | |
| » W: Rick Rhoden (7-4) L: Jay Tibbs (4-3) | Fifth | 18 out |
| Sunday, June 22 |
| » Lost to Expos (36-29), 2-1 | Stade Olympique (2-2) | 27-38 | |
| » W: Joe Hesketh (5-4) L: Rick Reuschel (4-7) S: Jeff Reardon (17) | Sixth | 19 out |
| Monday, June 23 |
| » Lost to Cardinals (30-37), 2-1 | Busch Stadium II (0-1) | 27-39 | Lost 2 |
| » W: Todd Worrell (5-7) L: Pat Clements (0-3) | Sixth | 19 out |
| Tuesday, June 24 |
| » Lost to Cardinals (31-37), 5-2 | Busch Stadium II (0-2) | 27-40 | Lost 3 |
| » W: Ray Burris (4-3) L: Jim Winn (1-2) S: Ken Dayley (4) | Sixth | 19 out |
| Wednesday, June 25 |
| » Lost to Cardinals (32-37), 2-1 | Busch Stadium II (0-3) | 27-41 | Lost 4 |
| » W: Ricky Horton (1-3) L: Pat Clements (0-4) | Sixth | 20 out |
| Friday, June 27 |
| » Defeated Expos (38-31), 7-1 | Three Rivers Stadium (14-23) | 28-41 | |
| » W: Rick Rhoden (8-4) L: Jay Tibbs (4-4) | Sixth | 19½ out |
| Saturday, June 28 |
| » Lost to Expos (39-31), 3-2 | Three Rivers Stadium (14-24) | 28-42 | |
| » W: Joe Hesketh (6-4) L: Rick Reuschel (4-8) S: Jeff Reardon (18) | Sixth | 20½ out |
| Sunday, June 29 |
| » Lost to Expos (40-31), 6-4 | Three Rivers Stadium (14-25) | 28-43 | Lost 2 |
| » W: Floyd Youmans (7-5) L: Mike Bielecki (4-5) S: Bob McClure (3) | Sixth | 21½ out |
| Monday, June 30 |
| » Defeated Phillies (35-37), 3-2 | Three Rivers Stadium (15-25) | 29-43 | |
| » W: Bob Walk (3-4) L: Charles Hudson (4-7) S: Cecilio Guante (4) | Fifth | 21½ out |
| Tuesday, July 1 |
| » Lost to Phillies (36-37), 5-4 | Three Rivers Stadium (15-26) | 29-44 | |
| » W: Tom Hume (1-0) L: Larry McWilliams (1-5) | Sixth | 22½ out |
| » Major-league debuts: Rich Sauveur (Pirates) |
| Wednesday, July 2 |
| » Defeated Phillies (36-38), 4-3 | Three Rivers Stadium (16-26) | 30-44 | |
| » W: Rick Rhoden (9-4) L: Don Carman (3-2) | Sixth | 22½ out |
| Thursday, July 3 |
| » Lost to Dodgers (35-43), 6-3 | Dodger Stadium (0-3) | 30-45 | |
| » W: Bob Welch (4-6) L: Rick Reuschel (4-9) | Sixth | 23½ out |
| Friday, July 4 |
| » Defeated Dodgers (35-44), 6-4 | Dodger Stadium (1-3) | 31-45 | |
| » W: Mike Bielecki (5-5) L: Fernando Valenzuela (10-6) | Fifth | 23½ out |
| Saturday, July 5 |
| » Defeated Dodgers (35-45), 5-0 | Dodger Stadium (2-3) | 32-45 | Won 2 |
| » W: Bob Walk (4-4) L: Orel Hershiser (7-6) | Fifth | 22½ out |
| Sunday, July 6 |
| » Lost to Dodgers (36-45), 4-3 | Dodger Stadium (2-4) | 32-46 | |
| » W: Rick Honeycutt (5-4) L: Jim Winn (1-3) S: Ken Howell (5) | Fifth | 23½ out |
| Monday, July 7 |
| » Defeated Padres (42-40), 3-1 | San Diego/Jack Murphy Stadium (4-0) | 33-46 | |
| » W: Cecilio Guante (3-1) L: Rich Gossage (4-4) | Fourth | 22½ out |
| Tuesday, July 8 |
| » Lost to Padres (43-40), 4-2 | San Diego/Jack Murphy Stadium (4-1) | 33-47 | |
| » W: LaMarr Hoyt (4-4) L: Rick Reuschel (4-10) S: Craig Lefferts (2) | Sixth | 22½ out |
| Wednesday, July 9 |
| » Defeated Padres (43-41), 6-4 | San Diego/Jack Murphy Stadium (5-1) | 34-47 | |
| » W: Mike Bielecki (6-5) L: Lance McCullers (4-3) S: Don Robinson (2) | Fifth | 21½ out |
| Former Pirate Red Lucas dies in Nashville, TN at the age of 85. |
| Thursday, July 10 |
| » Lost to Giants (46-39), 6-3 | Candlestick Park (1-2) | 34-48 | |
| » W: Vida Blue (6-4) L: Bob Walk (4-5) S: Scott Garrelts (1) | Fifth | 22½ out |
| Friday, July 11 |
| » Defeated Giants (46-40), 8-4 | Candlestick Park (2-2) | 35-48 | |
| » W: Jim Winn (2-3) L: Steve Carlton (4-9) S: Don Robinson (3) | Fifth | 22½ out |
| Saturday, July 12 |
| » Lost to Giants (47-40), 3-1 | Candlestick Park (2-3) | 35-49 | |
| » W: Mike Krukow (11-5) L: Rick Rhoden (9-5) | Sixth | 23½ out |
| Sunday, July 13 |
| » Lost to Giants (48-40), 11-4 | Candlestick Park (2-4) | 35-50 | Lost 2 |
| » W: Mike LaCoss (9-3) L: Rick Reuschel (4-11) | Sixth | 24½ out |
| Thursday, July 17 |
| » Lost to Padres (46-43), 2-1 | Three Rivers Stadium (16-27) | 35-51 | Lost 3 |
| » W: Lance McCullers (5-3) L: Rick Rhoden (9-6) S: Craig Lefferts (3) | Sixth | 25½ out |
| Friday, July 18 |
| » Defeated Padres (46-44), 12-7 | Three Rivers Stadium (17-27) | 36-51 | |
| » W: Rick Reuschel (5-11) L: Andy Hawkins (6-7) | Sixth | 24½ out |
| » Major-league debuts: Barry Jones (Pirates) |
| Saturday, July 19 |
| » Defeated Padres (46-45), 4-3 | Three Rivers Stadium (18-27) | 37-51 | Won 2 |
| » W: Cecilio Guante (4-1) L: Craig Lefferts (6-4) | Sixth | 23½ out |
| Sunday, July 20 |
| » Defeated Padres (46-46), 4-2 | Three Rivers Stadium (19-27) | 38-51 | Won 3 |
| » W: Larry McWilliams (2-5) L: Dave Dravecky (7-8) S: Don Robinson (4) | Fifth | 22½ out |
| Tuesday, July 22 |
| » Lost to Dodgers (43-50), 4-3 | Three Rivers Stadium (19-28) | 38-52 | |
| » W: Dennis Powell (1-3) L: Cecilio Guante (4-2) S: Ken Howell (8) | Sixth | 24 out |
| Wednesday, July 23 |
| » Lost to Dodgers (44-50), 6-5 | Three Rivers Stadium (19-29) | 38-53 | Lost 2 |
| » W: Orel Hershiser (9-7) L: Rick Reuschel (5-12) S: Ken Howell (9) | Sixth | 25 out |
| Thursday, July 24 |
| » Lost to Dodgers (45-50), 9-2 | Three Rivers Stadium (19-30) | 38-54 | Lost 3 |
| » W: Fernando Valenzuela (13-6) L: Bob Walk (4-6) | Sixth | 25½ out |
| Friday, July 25 |
| » Lost to Giants (51-45), 7-3 | Three Rivers Stadium (19-31) | 38-55 | Lost 4 |
| » W: Roger Mason (3-4) L: Mike Bielecki (6-6) S: Jeff Robinson (6) | Sixth | 26 out |
| Saturday, July 26 |
| » Lost to Giants (52-45), 9-0 | Three Rivers Stadium (19-32) | 38-56 | Lost 5 |
| » W: Steve Carlton (5-10) L: Larry McWilliams (2-6) | Sixth | 25½ out |
| Sunday, July 27 |
| » Defeated Giants (52-46), 7-0 | Three Rivers Stadium (20-32) | 39-56 | |
| » W: Rick Rhoden (10-6) L: Vida Blue (7-6) S: Don Robinson (5) | Sixth | 25½ out |
| Former Pirate Bud Hafey dies in Sacramento, CA at the age of 74. |
| Monday, July 28 |
| » Defeated Expos (49-47), 7-4 | Stade Olympique (3-2) | 40-56 | Won 2 |
| » W: Rick Reuschel (6-12) L: Bryn Smith (7-6) S: Barry Jones (2) | Sixth | 25½ out |
| Tuesday, July 29 |
| » Major-league debuts: Kelly Downs (Giants) |
| Wednesday, July 30 |
| » Lost to Expos (50-47), 3-2 | Stade Olympique (3-3) | 40-57 | |
| » W: Jay Tibbs (5-6) L: Jim Winn (2-4) S: Jeff Reardon (23) | Sixth | 25½ out |
| Friday, August 1 |
| » Defeated Cardinals (46-54), 4-0 | Three Rivers Stadium (21-32) | 41-57 | |
| » W: Rick Rhoden (11-6) L: Greg Mathews (6-3) | Sixth | 25½ out |
| Saturday, August 2 |
| » Lost to Cardinals (47-54), 7-3 | Three Rivers Stadium (21-33) | 41-58 | |
| » W: John Tudor (10-5) L: Larry McWilliams (2-7) | Sixth | 26½ out |
| Sunday, August 3 |
| » Defeated Cardinals (47-55), 3-0 | Three Rivers Stadium (22-33) | 42-58 | |
| » W: Rick Reuschel (7-12) L: Danny Cox (5-9) | Sixth | 26½ out |
| Monday, August 4 |
| » Lost to Expos (51-50), 5-4 | Three Rivers Stadium (22-34) | 42-59 | |
| » W: Jay Tibbs (6-6) L: Barry Jones (0-1) S: Jeff Reardon (24) | Sixth | 26½ out |
| Tuesday, August 5 |
| » Lost to Expos (52-50), 3-0 | Three Rivers Stadium (22-35) | 42-60 | Lost 2 |
| » W: Dennis Martinez (1-3) L: Mike Bielecki (6-7) | Sixth | 26½ out |
| Wednesday, August 6 |
| » Lost to Expos (53-50), 3-2 | Three Rivers Stadium (22-36) | 42-61 | Lost 3 |
| » W: Floyd Youmans (11-7) L: Rick Rhoden (11-7) S: Jeff Reardon (25) | Sixth | 27½ out |
| Thursday, August 7 |
| » Lost to Expos (54-50), 5-4 | Three Rivers Stadium (22-37) | 42-62 | Lost 4 |
| » W: Andy McGaffigan (6-4) L: Don Robinson (2-1) S: Bob McClure (5) | Sixth | 29 out |
| Friday, August 8 |
| » Lost to Cardinals (52-55), 3-1 | Busch Stadium II (0-4) | 42-63 | Lost 5 |
| » W: Danny Cox (6-9) L: Rick Reuschel (7-13) S: Ricky Horton (3) | Fifth | 29 out |
| Saturday, August 9 |
| » Defeated Cardinals (52-56), 8-5 | Busch Stadium II (1-4) | 43-63 | |
| » W: Bob Walk (5-6) L: Ray Burris (4-5) S: Don Robinson (6) | Sixth | 29 out |
| Sunday, August 10 |
| » Lost to Cardinals (53-56), 5-4 | Busch Stadium II (1-5) | 43-64 | |
| » W: Bob Forsch (12-6) L: Mike Bielecki (6-8) S: Todd Worrell (24) | Fifth | 30 out |
| Monday, August 11 |
| » Defeated Cubs (48-62), 10-7 | Wrigley Field (3-0) | 44-64 | |
| » W: Rick Rhoden (12-7) L: Jamie Moyer (3-3) S: Don Robinson (7) | Sixth | 29½ out |
| » Defeated Cubs (48-63), 10-8 | Wrigley Field (4-0) | 45-64 | Won 2 |
| » W: Barry Jones (1-1) L: Frank DiPino (1-7) | Sixth | 29½ out |
| Tuesday, August 12 |
| » Lost to Cubs (49-63), 3-1 | Wrigley Field (4-1) | 45-65 | |
| » W: Scott Sanderson (6-9) L: Larry McWilliams (2-8) S: Lee Smith (22) | Fifth | 29½ out |
| Wednesday, August 13 |
| » Lost to Cubs (50-63), 9-8 | Wrigley Field (4-2) | 45-66 | Lost 2 |
| » W: Frank DiPino (2-7) L: Don Robinson (2-2) S: Lee Smith (23) | Fifth | 29½ out |
| Thursday, August 14 |
| » Lost to Phillies (56-57), 8-7 | Veteran's Stadium (1-1) | 45-67 | Lost 3 |
| » W: Kent Tekulve (5-1) L: Barry Jones (1-2) | Sixth | 30 out |
| Friday, August 15 |
| » Defeated Phillies (56-58), 6-5 | Veteran's Stadium (2-1) | 46-67 | |
| » W: Cecilio Guante (5-2) L: Dan Schatzeder (3-4) S: Don Robinson (8) | Fifth | 29½ out |
| » Lost to Phillies (57-58), 3-2 | Veteran's Stadium (2-2) | 46-68 | |
| » W: Mike Maddux (1-5) L: Jim Winn (2-5) S: Steve Bedrosian (15) | Fifth | 29½ out |
| Saturday, August 16 |
| » Defeated Phillies (57-59), 6-1 | Veteran's Stadium (3-2) | 47-68 | |
| » W: Rick Rhoden (13-7) L: Kevin Gross (8-10) | Sixth | 29 out |
| » Lost to Phillies (58-59), 6-0 | Veteran's Stadium (3-3) | 47-69 | |
| » W: Tom Hume (4-0) L: Larry McWilliams (2-9) S: Kent Tekulve (3) | Sixth | 29 out |
| Sunday, August 17 |
| » Lost to Phillies (59-59), 5-1 | Veteran's Stadium (3-4) | 47-70 | Lost 2 |
| » W: Bruce Ruffin (5-3) L: Rick Reuschel (7-14) | Fifth | 29½ out |
| Monday, August 18 |
| » Lost to Astros (68-51), 3-0 | Three Rivers Stadium (22-38) | 47-71 | Lost 3 |
| » W: Mike Scott (13-8) L: Bob Walk (5-7) | Fifth | 30½ out |
| Tuesday, August 19 |
| » Lost to Astros (69-51), 1-0 | Three Rivers Stadium (22-39) | 47-72 | Lost 4 |
| » W: Jim Deshaies (8-3) L: Mike Bielecki (6-9) S: Dave Smith (25) | Sixth | 31½ out |
| Wednesday, August 20 |
| » Defeated Astros (69-52), 4-1 | Three Rivers Stadium (23-39) | 48-72 | |
| » W: Rick Rhoden (14-7) L: Bob Knepper (15-9) | Sixth | 31½ out |
| Friday, August 22 |
| » Defeated Braves (58-63), 16-5 | Three Rivers Stadium (24-39) | 49-72 | Won 2 |
| » W: Jim Winn (3-5) L: Rick Mahler (11-13) S: Barry Jones (3) | Sixth | 31½ out |
| Saturday, August 23 |
| » Defeated Braves (58-64), 4-3 | Three Rivers Stadium (25-39) | 50-72 | Won 3 |
| » W: Rick Reuschel (8-14) L: Zane Smith (7-12) S: Don Robinson (9) | Sixth | 31½ out |
| Sunday, August 24 |
| » Defeated Braves (58-65), 4-3 | Three Rivers Stadium (26-39) | 51-72 | Won 4 |
| » W: Bob Walk (6-7) L: Doyle Alexander (8-9) S: Don Robinson (10) | Sixth | 30½ out |
| Monday, August 25 |
| » Lost to Reds (63-62), 5-4 | Three Rivers Stadium (26-40) | 51-73 | |
| » W: Ron Robinson (9-3) L: Larry McWilliams (2-10) S: John Franco (22) | Sixth | 31½ out |
| Tuesday, August 26 |
| » Lost to Reds (64-62), 5-4 | Three Rivers Stadium (26-41) | 51-74 | Lost 2 |
| » W: John Franco (5-4) L: Ray Krawczyk (0-1) | Sixth | 32½ out |
| Wednesday, August 27 |
| » Lost to Reds (65-62), 9-5 | Three Rivers Stadium (26-42) | 51-75 | Lost 3 |
| » W: Rob Murphy (2-0) L: Don Robinson (2-3) | Sixth | 33½ out |
| Friday, August 29 |
| » Lost to Astros (73-55), 3-2 | Astrodome (2-2) | 51-76 | Lost 4 |
| » W: Mike Scott (14-9) L: Rick Reuschel (8-15) S: Dave Smith (27) | Sixth | 34½ out |
| Saturday, August 30 |
| » Defeated Astros (73-56), 13-3 | Astrodome (3-2) | 52-76 | |
| » W: Rick Rhoden (15-7) L: Jim Deshaies (9-4) | Sixth | 34½ out |
| Sunday, August 31 |
| » Defeated Astros (73-57), 8-2 | Astrodome (4-2) | 53-76 | Won 2 |
| » W: Bob Walk (7-7) L: Bob Knepper (15-10) | Sixth | 33½ out |
| Monday, September 1 |
| » Lost to Reds (67-64), 6-5 | Riverfront Stadium (1-3) | 53-77 | |
| » W: Ted Power (5-6) L: Mike Bielecki (6-10) S: John Franco (23) | Sixth | 34½ out |
| » Major-league debuts: John Smiley (Pirates) |
| Tuesday, September 2 |
| » Lost to Reds (68-64), 9-1 | Riverfront Stadium (1-4) | 53-78 | Lost 2 |
| » W: Bill Gullickson (13-8) L: Bob Kipper (3-7) | Sixth | 34½ out |
| Wednesday, September 3 |
| » Defeated Reds (68-65), 5-3 | Riverfront Stadium (2-4) | 54-78 | |
| » W: Barry Jones (2-2) L: John Franco (5-5) | Sixth | 34½ out |
| Thursday, September 4 |
| Former Pirate Hank Greenberg dies in Beverly Hills, CA at the age of 76. |
| Friday, September 5 |
| » Lost to Braves (63-70), 4-3 | Atlanta-Fulton County Stadium (2-2) | 54-79 | |
| » W: Paul Assenmacher (6-2) L: Rick Rhoden (15-8) | Sixth | 35 out |
| Saturday, September 6 |
| » Lost to Braves (64-70), 4-2 | Atlanta-Fulton County Stadium (2-3) | 54-80 | Lost 2 |
| » W: David Palmer (11-8) L: Stan Fansler (0-1) S: Jeff Dedmon (3) | Sixth | 36 out |
| Sunday, September 7 |
| » Defeated Braves (64-71), 3-1 | Atlanta-Fulton County Stadium (3-3) | 55-80 | |
| » W: Bob Kipper (4-7) L: Cliff Speck (2-1) S: Barry Jones (4) | Sixth | 36½ out |
| Monday, September 8 |
| » Defeated Cardinals (68-69), 3-2 | Three Rivers Stadium (27-42) | 56-80 | Won 2 |
| » W: Bob Patterson (1-2) L: Danny Cox (9-12) S: Hipolito Pena (1) | Sixth | 35½ out |
| Tuesday, September 9 |
| » Lost to Cardinals (69-69), 3-1 | Three Rivers Stadium (27-43) | 56-81 | |
| » W: Ricky Horton (3-3) L: Rick Reuschel (8-16) S: Todd Worrell (32) | Sixth | 35½ out |
| Wednesday, September 10 |
| » Lost to Cardinals (70-69), 4-3 | Three Rivers Stadium (27-44) | 56-82 | Lost 2 |
| » W: Ray Soff (3-0) L: Barry Jones (2-3) S: Todd Worrell (33) | Sixth | 36½ out |
| Friday, September 12 |
| » Lost to Cubs (60-80), 9-8 | Three Rivers Stadium (27-45) | 56-83 | Lost 3 |
| » W: Frank DiPino (3-7) L: Don Robinson (2-4) S: Dave Gumpert (3) | Sixth | 36½ out |
| Saturday, September 13 |
| » Defeated Cubs (60-81), 5-2 | Three Rivers Stadium (28-45) | 57-83 | |
| » W: Bob Patterson (2-2) L: Greg Maddux (1-2) S: Don Robinson (11) | Sixth | 35½ out |
| Sunday, September 14 |
| » Defeated Cubs (60-82), 9-2 | Three Rivers Stadium (29-45) | 58-83 | Won 2 |
| » W: Rick Reuschel (9-16) L: Drew Hall (0-1) | Sixth | 34½ out |
| » Major-league debuts: Drew Hall (Cubs) |
| Monday, September 15 |
| » Lost to Phillies (75-68), 5-0 | Veteran's Stadium (3-5) | 58-84 | |
| » W: Don Carman (9-5) L: Rick Rhoden (15-9) | Sixth | 34½ out |
| Tuesday, September 16 |
| » Lost to Phillies (76-68), 9-5 | Veteran's Stadium (3-6) | 58-85 | Lost 2 |
| » W: Kent Tekulve (11-4) L: Mike Bielecki (6-11) | Sixth | 35½ out |
| » Major-league debuts: Marvin Freeman (Phillies) |
| Wednesday, September 17 |
| » Lost to Expos (72-71), 6-5 | Stade Olympique (3-4) | 58-86 | Lost 3 |
| » W: Randy St. Claire (1-0) L: Barry Jones (2-4) S: Jeff Reardon (34) | Sixth | 36 out |
| » Defeated Expos (72-72), 4-1 | Stade Olympique (4-4) | 59-86 | |
| » W: Bob Kipper (5-7) L: Bob Sebra (4-5) S: Don Robinson (12) | Sixth | 36 out |
| Thursday, September 18 |
| » Defeated Expos (72-73), 3-1 | Stade Olympique (5-4) | 60-86 | Won 2 |
| » W: John Smiley (1-0) L: Jeff Reardon (7-9) S: Don Robinson (13) | Sixth | 36 out |
| Friday, September 19 |
| » Lost to Cubs (62-85), 8-2 | Wrigley Field (4-3) | 60-87 | |
| » W: Scott Sanderson (8-11) L: Hipolito Pena (0-1) | Sixth | 36 out |