| Monday, April 7 |
| » Major-league debuts: John Kruk (Padres) |
| Tuesday, April 8 |
| » Defeated Angels (0-1), 8-4 | Kingdome (1-0) | 1-0 | |
| » W: Pete Ladd (1-0) L: Ken Forsch (0-1) | First | -- |
| » Major-league debuts: Wally Joyner (Angels) |
| Wednesday, April 9 |
| » Lost to Angels (1-1), 9-5 | Kingdome (1-1) | 1-1 | |
| » W: Jim Slaton (1-0) L: Mark Langston (0-1) | Second | 1 out |
| Thursday, April 10 |
| » Defeated Angels (1-2), 5-2 | Kingdome (2-1) | 2-1 | |
| » W: Matt Young (1-0) L: Don Sutton (0-1) | First | -- |
| Friday, April 11 |
| » Lost to Twins (3-1), 5-1 | Hubert H. Humphrey Metrodome (0-1) | 2-2 | |
| » W: Bert Blyleven (1-0) L: Milt Wilcox (0-1) S: Ron Davis (2) | Second | 1 out |
| Saturday, April 12 |
| » Defeated Twins (3-2), 10-4 | Hubert H. Humphrey Metrodome (1-1) | 3-2 | |
| » W: Mike Morgan (1-0) L: Frank Viola (1-1) | First | -- |
| Sunday, April 13 |
| » Defeated Twins (3-3), 4-2 | Hubert H. Humphrey Metrodome (2-1) | 4-2 | Won 2 |
| » W: Mike Moore (1-0) L: Mike Smithson (1-1) | First | -- |
| Monday, April 14 |
| » Lost to Angels (4-3), 7-6 | Anaheim Stadium (0-1) | 4-3 | |
| » W: Donnie Moore (1-0) L: Pete Ladd (1-1) | First | -- |
| Tuesday, April 15 |
| » Defeated Angels (4-4), 9-4 | Anaheim Stadium (1-1) | 5-3 | |
| » W: Matt Young (2-0) L: Don Sutton (0-2) S: Mike Morgan (1) | First | -- |
| Wednesday, April 16 |
| » Lost to Angels (5-4), 4-0 | Anaheim Stadium (1-2) | 5-4 | |
| » W: Ron Romanick (2-0) L: Milt Wilcox (0-2) | Third | ½ out |
| Friday, April 18 |
| » Lost to Athletics (5-5), 4-1 | Kingdome (2-2) | 5-5 | Lost 2 |
| » W: Chris Codiroli (2-1) L: Mike Moore (1-1) S: Jay Howell (3) | Fourth | 1½ out |
| Saturday, April 19 |
| » Lost to Athletics (6-5), 7-2 | Kingdome (2-3) | 5-6 | Lost 3 |
| » W: Jose Rijo (1-0) L: Mark Langston (0-2) | Fourth | 1½ out |
| Sunday, April 20 |
| » Lost to Athletics (7-5), 9-3 | Kingdome (2-4) | 5-7 | Lost 4 |
| » W: Moose Haas (3-0) L: Matt Young (2-1) | Fourth | 2½ out |
| Monday, April 21 |
| » Lost to Twins (6-8), 5-2 | Kingdome (2-5) | 5-8 | Lost 5 |
| » W: Frank Viola (3-1) L: Milt Wilcox (0-3) | Sixth | 3 out |
| Tuesday, April 22 |
| » Lost to Twins (7-8), 7-1 | Kingdome (2-6) | 5-9 | Lost 6 |
| » W: Mike Smithson (2-2) L: Mike Morgan (1-1) | Sixth | 3½ out |
| Wednesday, April 23 |
| » Defeated Twins (7-9), 4-3 | Kingdome (3-6) | 6-9 | |
| » W: Karl Best (1-0) L: Mark Portugal (0-1) | Sixth | 3½ out |
| Thursday, April 24 |
| » Defeated Athletics (8-8), 3-1 | Oakland-Alameda County Stadium (1-0) | 7-9 | Won 2 |
| » W: Mark Langston (1-2) L: Jose Rijo (1-1) S: Karl Best (1) | Fifth | 3 out |
| Friday, April 25 |
| » Lost to Athletics (9-8), 11-2 | Oakland-Alameda County Stadium (1-1) | 7-10 | |
| » W: Moose Haas (4-0) L: Matt Young (2-2) | Sixth | 3 out |
| Saturday, April 26 |
| » Lost to Athletics (10-8), 5-3 | Oakland-Alameda County Stadium (1-2) | 7-11 | Lost 2 |
| » W: Joaquin Andujar (2-1) L: Milt Wilcox (0-4) | Sixth | 4 out |
| Sunday, April 27 |
| » Lost to Athletics (11-8), 1-0 | Oakland-Alameda County Stadium (1-3) | 7-12 | Lost 3 |
| » W: Rick Langford (1-2) L: Mike Morgan (1-2) S: Jay Howell (4) | Sixth | 5 out |
| Tuesday, April 29 |
| » Lost to Red Sox (10-8), 3-1 | Fenway Park (0-1) | 7-13 | Lost 4 |
| » W: Roger Clemens (4-0) L: Mike Moore (1-2) | Sixth | 6 out |
| Wednesday, April 30 |
| » Lost to Red Sox (11-8), 9-4 | Fenway Park (0-2) | 7-14 | Lost 5 |
| » W: Sammy Stewart (1-1) L: Ed Nunez (0-1) S: Bob Stanley (2) | Sixth | 6 out |
| Thursday, May 1 |
| » Lost to Red Sox (12-8), 12-2 | Fenway Park (0-3) | 7-15 | Lost 6 |
| » W: Oil Can Boyd (2-2) L: Bill Swift (0-1) | Sixth | 7 out |
| Friday, May 2 |
| » Defeated Blue Jays (9-13), 3-2 | Exhibition Stadium (1-0) | 8-15 | |
| » W: Pete Ladd (2-1) L: Mark Eichhorn (2-2) | Sixth | 6 out |
| Saturday, May 3 |
| » Defeated Blue Jays (9-14), 4-2 | Exhibition Stadium (2-0) | 9-15 | Won 2 |
| » W: Mike Morgan (2-2) L: Jim Acker (0-2) S: Pete Ladd (1) | Fifth | 5 out |
| Sunday, May 4 |
| » Lost to Blue Jays (10-14), 3-2 | Exhibition Stadium (2-1) | 9-16 | |
| » W: Tom Henke (3-1) L: Mike Moore (1-3) | Fifth | 5 out |
| Monday, May 5 |
| » Lost to Brewers (13-10), 3-1 | County Stadium (0-1) | 9-17 | Lost 2 |
| » W: Tim Leary (3-2) L: Mark Langston (1-3) S: Dan Plesac (2) | Fifth | 5 out |
| Tuesday, May 6 |
| » Lost to Brewers (14-10), 10-0 | County Stadium (0-2) | 9-18 | Lost 3 |
| » W: Juan Nieves (2-1) L: Bill Swift (0-2) | Sixth | 6 out |
| Wednesday, May 7 |
| » Lost to Red Sox (16-10), 11-5 | Kingdome (3-7) | 9-19 | Lost 4 |
| » W: Al Nipper (3-3) L: Milt Wilcox (0-5) | Sixth | 7 out |
| Thursday, May 8 |
| » Lost to Red Sox (17-10), 4-2 | Kingdome (3-8) | 9-20 | Lost 5 |
| » Manager: Marty Martinez |
| » W: Mike Brown (2-0) L: Mike Morgan (2-3) S: Bob Stanley (5) | Fifth | 7 out |
| Friday, May 9 |
| » Defeated Blue Jays (12-17), 13-3 | Kingdome (4-8) | 10-20 | |
| » Manager: Dick Williams |
| » W: Mike Moore (2-3) L: Dave Stieb (0-4) | Fifth | 6 out |
| Saturday, May 10 |
| » Defeated Blue Jays (12-18), 8-7 | Kingdome (5-8) | 11-20 | Won 2 |
| » W: Pete Ladd (3-1) L: Tom Henke (3-2) | Fifth | 5 out |
| Sunday, May 11 |
| » Lost to Blue Jays (13-18), 4-3 | Kingdome (5-9) | 11-21 | |
| » W: Jimmy Key (1-3) L: Bill Swift (0-3) S: Mark Eichhorn (1) | Seventh | 6 out |
| Monday, May 12 |
| » Defeated Brewers (16-14), 6-0 | Kingdome (6-9) | 12-21 | |
| » W: Matt Young (3-2) L: Teddy Higuera (4-3) | Sixth | 6 out |
| » Major-league debuts: Dale Sveum (Brewers) |
| Tuesday, May 13 |
| » Defeated Brewers (16-15), 8-5 | Kingdome (7-9) | 13-21 | Won 2 |
| » W: Mike Morgan (3-3) L: Tim Leary (3-3) S: Pete Ladd (2) | Sixth | 6 out |
| Wednesday, May 14 |
| » Lost to Brewers (17-15), 9-6 | Kingdome (7-10) | 13-22 | |
| » W: Dan Plesac (2-1) L: Mike Moore (2-4) | Sixth | 6 out |
| Friday, May 16 |
| » Defeated Yankees (21-14), 7-3 | Yankee Stadium (1-0) | 14-22 | |
| » W: Mark Langston (2-3) L: Joe Niekro (4-2) S: Pete Ladd (3) | Sixth | 6 out |
| Saturday, May 17 |
| » Lost to Yankees (22-14), 11-6 | Yankee Stadium (1-1) | 14-23 | |
| » W: Bob Tewksbury (4-2) L: Matt Young (3-3) | Sixth | 6 out |
| Sunday, May 18 |
| » Lost to Yankees (23-14), 11-3 | Yankee Stadium (1-2) | 14-24 | Lost 2 |
| » W: Dennis Rasmussen (4-1) L: Mike Morgan (3-4) | Seventh | 6½ out |
| Tuesday, May 20 |
| » Lost to Tigers (17-18), 12-0 | Tiger Stadium (0-1) | 14-25 | Lost 3 |
| » W: Walt Terrell (5-1) L: Mike Moore (2-5) | Sixth | 7½ out |
| Wednesday, May 21 |
| » Lost to Tigers (18-18), 6-4 | Tiger Stadium (0-2) | 14-26 | Lost 4 |
| » W: Eric King (1-0) L: Mark Langston (2-4) | Sixth | 7½ out |
| Thursday, May 22 |
| » Defeated Tigers (18-19), 5-3 | Tiger Stadium (1-2) | 15-26 | |
| » W: Matt Young (4-3) L: Dan Petry (3-4) S: Pete Ladd (4) | Sixth | 6½ out |
| Friday, May 23 |
| » Lost to Orioles (23-16), 7-5 | Kingdome (7-11) | 15-27 | |
| » W: Ken Dixon (5-2) L: Mike Morgan (3-5) S: Don Aase (11) | Seventh | 6½ out |
| Saturday, May 24 |
| » Lost to Orioles (24-16), 5-4 | Kingdome (7-12) | 15-28 | Lost 2 |
| » W: Nate Snell (1-0) L: Mark Huismann (0-2) | Seventh | 7 out |
| Sunday, May 25 |
| » Lost to Orioles (25-16), 6-3 | Kingdome (7-13) | 15-29 | Lost 3 |
| » W: Mike Boddicker (5-1) L: Mike Moore (2-6) | Seventh | 7 out |
| Monday, May 26 |
| » Defeated Orioles (25-17), 7-6 | Kingdome (8-13) | 16-29 | |
| » W: Mark Langston (3-4) L: Storm Davis (4-3) S: Matt Young (1) | Seventh | 7 out |
| Wednesday, May 28 |
| » Lost to Yankees (29-16), 6-5 | Kingdome (8-14) | 16-30 | |
| » W: Ed Whitson (4-1) L: Mike Morgan (3-6) S: Dave Righetti (11) | Seventh | 8½ out |
| Thursday, May 29 |
| » Lost to Yankees (30-16), 2-0 | Kingdome (8-15) | 16-31 | Lost 2 |
| » W: Dennis Rasmussen (5-1) L: Milt Wilcox (0-6) S: Dave Righetti (12) | Seventh | 9 out |
| Friday, May 30 |
| » Defeated Tigers (23-21), 8-7 | Kingdome (9-15) | 17-31 | |
| » W: Mark Huismann (1-2) L: Chuck Cary (0-1) | Seventh | 8 out |
| Saturday, May 31 |
| » Defeated Tigers (23-22), 7-4 | Kingdome (10-15) | 18-31 | Won 2 |
| » W: Mark Langston (4-4) L: Walt Terrell (6-2) S: Matt Young (2) | Seventh | 7 out |
| Sunday, June 1 |
| » Defeated Tigers (23-23), 9-1 | Kingdome (11-15) | 19-31 | Won 3 |
| » W: Bill Swift (1-3) L: Frank Tanana (4-4) S: Mark Huismann (2) | Sixth | 6 out |
| Tuesday, June 3 |
| » Lost to Orioles (29-19), 4-2 | Memorial Stadium (0-1) | 19-32 | |
| » W: Mike Boddicker (6-1) L: Milt Wilcox (0-7) S: Don Aase (14) | Sixth | 7½ out |
| Wednesday, June 4 |
| » Defeated Orioles (29-20), 5-1 | Memorial Stadium (1-1) | 20-32 | |
| » W: Mike Moore (3-6) L: Ken Dixon (5-3) | Fifth | 7½ out |
| Thursday, June 5 |
| » Lost to Orioles (30-20), 7-1 | Memorial Stadium (1-2) | 20-33 | |
| » W: Storm Davis (5-4) L: Mark Langston (4-5) | Sixth | 8 out |
| Friday, June 6 |
| » Lost to Rangers (28-24), 6-5 | Arlington Stadium (0-1) | 20-34 | Lost 2 |
| » W: Mitch Williams (4-0) L: Pete Ladd (3-2) | Sixth | 9 out |
| Saturday, June 7 |
| » Lost to Rangers (29-24), 7-5 | Arlington Stadium (0-2) | 20-35 | Lost 3 |
| » W: Jose Guzman (5-6) L: Matt Young (4-4) S: Greg Harris (9) | Seventh | 11 out |
| » Lost to Rangers (30-24), 3-2 | Arlington Stadium (0-3) | 20-36 | Lost 4 |
| » W: Charlie Hough (5-2) L: Lee Guetterman (0-1) S: Greg Harris (10) | Seventh | 11 out |
| Sunday, June 8 |
| » Lost to Rangers (31-24), 5-4 | Arlington Stadium (0-4) | 20-37 | Lost 5 |
| » W: Mitch Williams (5-0) L: Karl Best (1-1) | Seventh | 12 out |
| Monday, June 9 |
| » Defeated Royals (28-28), 5-3 | Royals Stadium (1-0) | 21-37 | |
| » W: Mark Langston (5-5) L: Dennis Leonard (6-5) S: Mark Huismann (3) | Sixth | 11 out |
| Tuesday, June 10 |
| » Lost to Royals (29-28), 9-5 | Royals Stadium (1-1) | 21-38 | |
| » W: Steve Farr (4-1) L: Milt Wilcox (0-8) | Seventh | 12 out |
| Wednesday, June 11 |
| » Defeated Royals (29-29), 12-2 | Royals Stadium (2-1) | 22-38 | |
| » W: Mike Morgan (4-6) L: Charlie Leibrandt (6-4) | Sixth | 12 out |
| » Major-league debuts: Mike Brewer (Royals) |
| Thursday, June 12 |
| » Lost to White Sox (25-33), 8-4 | Kingdome (11-16) | 22-39 | |
| » W: Joe Cowley (3-3) L: Lee Guetterman (0-2) | Seventh | 12½ out |
| Friday, June 13 |
| » Defeated White Sox (25-34), 11-10 | Kingdome (12-16) | 23-39 | |
| » W: Matt Young (5-4) L: Bill Dawley (0-4) | Sixth | 12½ out |
| Saturday, June 14 |
| » Defeated White Sox (25-35), 7-3 | Kingdome (13-16) | 24-39 | Won 2 |
| » W: Mark Langston (6-5) L: Tom Seaver (2-5) S: Matt Young (3) | Seventh | 11½ out |
| Sunday, June 15 |
| » Defeated White Sox (25-36), 10-5 | Kingdome (14-16) | 25-39 | Won 3 |
| » W: Steve Fireovid (1-0) L: Joel McKeon (2-1) | Sixth | 10½ out |
| Tuesday, June 17 |
| » Defeated Indians (30-31), 5-2 | Cleveland Stadium (1-0) | 26-39 | Won 4 |
| » W: Mike Morgan (5-6) L: Phil Niekro (3-6) | Sixth | 9 out |
| Wednesday, June 18 |
| » Lost to Indians (31-31), 5-1 | Cleveland Stadium (1-1) | 26-40 | |
| » W: Ken Schrom (6-2) L: Jim Beattie (0-1) S: Scott Bailes (6) | Seventh | 9 out |
| Thursday, June 19 |
| » Lost to Indians (32-31), 8-1 | Cleveland Stadium (1-2) | 26-41 | Lost 2 |
| » W: Tom Candiotti (5-6) L: Mike Moore (3-7) | Seventh | 10 out |
| Friday, June 20 |
| » Defeated White Sox (26-39), 5-3 | Comiskey Park I (1-0) | 27-41 | |
| » W: Mark Langston (7-5) L: Tom Seaver (2-6) S: Matt Young (4) | Seventh | 10 out |
| Saturday, June 21 |
| » Lost to White Sox (27-39), 7-6 | Comiskey Park I (1-1) | 27-42 | |
| » W: Neil Allen (4-0) L: Bill Swift (1-4) S: Bill Dawley (1) | Seventh | 11 out |
| Sunday, June 22 |
| » Lost to White Sox (28-39), 10-4 | Comiskey Park I (1-2) | 27-43 | Lost 2 |
| » W: Richard Dotson (5-7) L: Mike Morgan (5-7) | Seventh | 12 out |
| Monday, June 23 |
| » Lost to Indians (35-32), 8-6 | Kingdome (14-17) | 27-44 | Lost 3 |
| » W: Ken Schrom (7-2) L: Jim Beattie (0-2) S: Ernie Camacho (9) | Seventh | 12 out |
| Tuesday, June 24 |
| » Defeated Indians (35-33), 8-7 | Kingdome (15-17) | 28-44 | |
| » W: Matt Young (6-4) L: Ernie Camacho (1-1) | Sixth | 11 out |
| Wednesday, June 25 |
| » Defeated Indians (35-34), 6-1 | Kingdome (16-17) | 29-44 | Won 2 |
| » W: Mark Langston (8-5) L: John Butcher (0-4) | Sixth | 11 out |
| Thursday, June 26 |
| » Lost to Rangers (39-33), 10-3 | Kingdome (16-18) | 29-45 | |
| » W: Charlie Hough (7-3) L: Lee Guetterman (0-3) | Sixth | 11½ out |
| Friday, June 27 |
| » Defeated Rangers (39-34), 6-5 | Kingdome (17-18) | 30-45 | |
| » W: Matt Young (7-4) L: Jeff Russell (1-1) | Sixth | 10½ out |
| Saturday, June 28 |
| » Lost to Rangers (40-34), 5-2 | Kingdome (17-19) | 30-46 | |
| » W: Jose Guzman (7-8) L: Jim Beattie (0-3) | Sixth | 11½ out |
| Sunday, June 29 |
| » Defeated Rangers (40-35), 9-3 | Kingdome (18-19) | 31-46 | |
| » W: Mike Moore (4-7) L: Ed Correa (5-6) | Sixth | 10½ out |
| Monday, June 30 |
| » Defeated Royals (37-39), 3-2 | Kingdome (19-19) | 32-46 | Won 2 |
| » W: Mark Langston (9-5) L: Dennis Leonard (6-7) S: Matt Young (5) | Sixth | 9½ out |
| Tuesday, July 1 |
| » Defeated Royals (37-40), 8-5 | Kingdome (20-19) | 33-46 | Won 3 |
| » W: Pete Ladd (4-2) L: Dan Quisenberry (0-2) | Sixth | 9 out |
| Wednesday, July 2 |
| » Defeated Royals (37-41), 5-3 | Kingdome (21-19) | 34-46 | Won 4 |
| » W: Mike Morgan (6-7) L: Scott Bankhead (3-2) S: Matt Young (6) | Sixth | 9 out |
| Friday, July 4 |
| » Lost to Red Sox (51-27), 6-5 | Fenway Park (0-4) | 34-47 | |
| » W: Jeff Sellers (2-3) L: Jim Beattie (0-4) S: Joe Sambito (8) | Sixth | 10 out |
| Saturday, July 5 |
| » Defeated Red Sox (51-28), 9-5 | Fenway Park (1-4) | 35-47 | |
| » W: Mike Moore (5-7) L: Al Nipper (4-5) S: Matt Young (7) | Sixth | 10 out |
| Sunday, July 6 |
| » Lost to Red Sox (52-28), 7-3 | Fenway Park (1-5) | 35-48 | |
| » W: Tom Seaver (4-6) L: Mark Langston (9-6) S: Bob Stanley (14) | Sixth | 10 out |
| Monday, July 7 |
| » Lost to Blue Jays (44-40), 7-5 | Exhibition Stadium (2-2) | 35-49 | Lost 2 |
| » W: Jimmy Key (8-5) L: Mike Morgan (6-8) S: Bill Caudill (1) | Sixth | 10½ out |
| Tuesday, July 8 |
| » Defeated Blue Jays (44-41), 8-5 | Exhibition Stadium (3-2) | 36-49 | |
| » W: Mark Huismann (2-2) L: John Cerutti (4-2) S: Matt Young (8) | Sixth | 10½ out |
| Wednesday, July 9 |
| » Lost to Blue Jays (45-41), 6-5 | Exhibition Stadium (3-3) | 36-50 | |
| » W: Bill Caudill (2-0) L: Mike Moore (5-8) S: Tom Henke (13) | Sixth | 11½ out |
| Thursday, July 10 |
| » Defeated Brewers (40-43), 4-1 | County Stadium (1-2) | 37-50 | |
| » W: Steve Fireovid (2-0) L: Danny Darwin (5-5) S: Pete Ladd (5) | Fifth | 10½ out |
| Friday, July 11 |
| » Defeated Brewers (40-44), 9-3 | County Stadium (2-2) | 38-50 | Won 2 |
| » W: Mike Morgan (7-8) L: Tim Leary (6-9) | Fifth | 10½ out |
| Saturday, July 12 |
| » Defeated Brewers (40-45), 15-9 | County Stadium (3-2) | 39-50 | Won 3 |
| » W: Jerry Reed (1-0) L: Bill Wegman (2-8) S: Mark Huismann (4) | Fifth | 9½ out |
| Sunday, July 13 |
| » Lost to Brewers (41-45), 5-0 | County Stadium (3-3) | 39-51 | |
| » W: Juan Nieves (8-3) L: Mike Moore (5-9) | Fifth | 10½ out |
| Thursday, July 17 |
| » Defeated Red Sox (56-32), 5-1 | Kingdome (22-19) | 40-51 | |
| » W: Pete Ladd (5-2) L: Bob Stanley (5-3) | Fifth | 9½ out |
| Friday, July 18 |
| » Defeated Red Sox (56-33), 10-4 | Kingdome (23-19) | 41-51 | Won 2 |
| » W: Mike Moore (6-9) L: Al Nipper (4-6) | Fifth | 8½ out |
| Saturday, July 19 |
| » Lost to Red Sox (57-33), 9-4 | Kingdome (23-20) | 41-52 | |
| » W: Roger Clemens (16-2) L: Mike Morgan (7-9) | Fifth | 9½ out |
| Sunday, July 20 |
| » Defeated Red Sox (57-34), 9-5 | Kingdome (24-20) | 42-52 | |
| » W: Jerry Reed (2-0) L: Jeff Sellers (3-5) | Fifth | 8½ out |
| Monday, July 21 |
| » Lost to Blue Jays (51-44), 8-3 | Kingdome (24-21) | 42-53 | |
| » W: John Cerutti (5-2) L: Mark Huismann (2-3) | Fifth | 8½ out |
| Tuesday, July 22 |
| » Defeated Blue Jays (51-45), 8-7 | Kingdome (25-21) | 43-53 | |
| » W: Jerry Reed (3-0) L: Bill Caudill (2-2) | Fifth | 7½ out |
| Wednesday, July 23 |
| » Lost to Blue Jays (52-45), 6-2 | Kingdome (25-22) | 43-54 | |
| » W: Jim Clancy (11-5) L: Mike Moore (6-10) S: Dave Stieb (1) | Fifth | 8½ out |
| Friday, July 25 |
| » Lost to Brewers (45-49), 4-2 | Kingdome (25-23) | 43-55 | Lost 2 |
| » W: Teddy Higuera (12-7) L: Mike Morgan (7-10) S: Mark Clear (6) | Fifth | 8½ out |
| Saturday, July 26 |
| » Defeated Brewers (45-50), 5-2 | Kingdome (26-23) | 44-55 | |
| » W: Jerry Reed (4-0) L: Bill Wegman (3-9) S: Matt Young (9) | Fourth | 8½ out |
| Sunday, July 27 |
| » Lost to Brewers (46-50), 8-1 | Kingdome (26-24) | 44-56 | |
| » W: Tim Leary (7-10) L: Mark Langston (9-7) | Fourth | 9½ out |
| Monday, July 28 |
| » Lost to Twins (42-57), 6-5 | Hubert H. Humphrey Metrodome (2-2) | 44-57 | Lost 2 |
| » W: Keith Atherton (5-3) L: Karl Best (1-2) | Fourth | 10½ out |
| Tuesday, July 29 |
| » Lost to Twins (43-57), 4-2 | Hubert H. Humphrey Metrodome (2-3) | 44-58 | Lost 3 |
| » W: Frank Viola (11-8) L: Jim Beattie (0-5) S: Roy Lee Jackson (1) | Fifth | 10½ out |
| Wednesday, July 30 |
| » Defeated Twins (43-58), 4-2 | Hubert H. Humphrey Metrodome (3-3) | 45-58 | |
| » W: Mike Morgan (8-10) L: Neal Heaton (4-10) S: Matt Young (10) | Fifth | 10½ out |
| Friday, August 1 |
| » Lost to Angels (56-46), 3-2 | Kingdome (26-25) | 45-59 | |
| » W: Don Sutton (10-7) L: Mark Langston (9-8) S: Donnie Moore (13) | Fifth | 12 out |
| Saturday, August 2 |
| » Defeated Angels (56-47), 7-3 | Kingdome (27-25) | 46-59 | |
| » W: Mark Huismann (3-3) L: Kirk McCaskill (12-7) | Fifth | 11 out |
| Sunday, August 3 |
| » Defeated Angels (56-48), 6-3 | Kingdome (28-25) | 47-59 | Won 2 |
| » W: Pete Ladd (6-2) L: Ray Chadwick (0-2) | Fifth | 10 out |
| Monday, August 4 |
| » Defeated Athletics (45-63), 9-8 | Kingdome (29-25) | 48-59 | Won 3 |
| » W: Karl Best (2-2) L: Bill Mooneyham (3-4) S: Mike Moore (1) | Fourth | 9 out |
| Tuesday, August 5 |
| » Lost to Athletics (46-63), 10-4 | Kingdome (29-26) | 48-60 | |
| » W: Curt Young (8-7) L: Jim Beattie (0-6) | Fifth | 10 out |
| Wednesday, August 6 |
| » Lost to Athletics (47-63), 7-5 | Kingdome (29-27) | 48-61 | Lost 2 |
| » W: Jay Howell (1-4) L: Matt Young (7-5) | Fifth | 10 out |
| Thursday, August 7 |
| » Lost to Angels (58-50), 4-3 | Anaheim Stadium (1-3) | 48-62 | Lost 3 |
| » W: Donnie Moore (2-4) L: Pete Ladd (6-3) | Sixth | 11 out |
| Friday, August 8 |
| » Lost to Angels (59-50), 6-4 | Anaheim Stadium (1-4) | 48-63 | Lost 4 |
| » W: Vern Ruhle (1-0) L: Bill Swift (1-5) S: Doug Corbett (9) | Sixth | 12 out |
| Saturday, August 9 |
| » Lost to Angels (60-50), 5-0 | Anaheim Stadium (1-5) | 48-64 | Lost 5 |
| » W: John Candelaria (5-1) L: Mike Morgan (8-11) | Sixth | 13 out |
| » Major-league debuts: Mickey Brantley (Mariners) |
| Sunday, August 10 |
| » Lost to Angels (61-50), 4-0 | Anaheim Stadium (1-6) | 48-65 | Lost 6 |
| » W: Mike Witt (13-7) L: Mark Langston (9-9) | Seventh | 14 out |
| Monday, August 11 |
| » Defeated Athletics (50-65), 6-4 | Oakland-Alameda County Stadium (2-3) | 49-65 | |
| » W: Pete Ladd (7-3) L: Doug Bair (2-3) | Seventh | 13 out |
| Tuesday, August 12 |
| » Lost to Athletics (51-65), 3-2 | Oakland-Alameda County Stadium (2-4) | 49-66 | |
| » W: Jay Howell (2-4) L: Pete Ladd (7-4) | Seventh | 14 out |
| Wednesday, August 13 |
| » Lost to Athletics (52-65), 4-1 | Oakland-Alameda County Stadium (2-5) | 49-67 | Lost 2 |
| » W: Dave Stewart (5-1) L: Mike Morgan (8-12) S: Jay Howell (10) | Seventh | 14 out |
| Thursday, August 14 |
| » Lost to Twins (51-64), 14-1 | Kingdome (29-28) | 49-68 | Lost 3 |
| » W: Mark Portugal (3-8) L: Mark Langston (9-10) | Sixth | 14½ out |
| Friday, August 15 |
| » Defeated Twins (51-65), 1-0 | Kingdome (30-28) | 50-68 | |
| » W: Mike Moore (7-10) L: Keith Atherton (5-6) | Sixth | 14½ out |
| Saturday, August 16 |
| » Defeated Twins (51-66), 7-6 | Kingdome (31-28) | 51-68 | Won 2 |
| » W: Pete Ladd (8-4) L: Keith Atherton (5-7) | Seventh | 14½ out |
| Sunday, August 17 |
| » Defeated Twins (51-67), 11-1 | Kingdome (32-28) | 52-68 | Won 3 |
| » W: Mike Morgan (9-12) L: Mike Smithson (9-11) | Fifth | 14½ out |
| Tuesday, August 19 |
| » Defeated Yankees (65-55), 7-3 | Yankee Stadium (2-2) | 53-68 | Won 4 |
| » W: Mark Langston (10-10) L: Tommy John (5-2) | Fifth | 14 out |
| Wednesday, August 20 |
| » Lost to Yankees (66-55), 5-2 | Yankee Stadium (2-3) | 53-69 | |
| » W: Tim Stoddard (3-3) L: Mike Moore (7-11) S: Dave Righetti (29) | Sixth | 14 out |
| Friday, August 22 |
| » Lost to Tigers (66-58), 4-1 | Tiger Stadium (1-3) | 53-70 | Lost 2 |
| » W: Eric King (9-3) L: Mike Morgan (9-13) | Sixth | 14½ out |
| Saturday, August 23 |
| » Lost to Tigers (67-58), 14-0 | Tiger Stadium (1-4) | 53-71 | Lost 3 |
| » W: Frank Tanana (10-6) L: Mike Brown (4-5) | Seventh | 14½ out |
| Sunday, August 24 |
| » Defeated Tigers (67-59), 3-1 | Tiger Stadium (2-4) | 54-71 | |
| » W: Mark Langston (11-10) L: Dan Petry (4-7) S: Matt Young (11) | Sixth | 14½ out |
| Tuesday, August 26 |
| » Defeated Orioles (64-59), 5-2 | Kingdome (33-28) | 55-71 | Won 2 |
| » W: Mike Moore (8-11) L: Ken Dixon (10-10) S: Matt Young (12) | Fifth | 15 out |
| Wednesday, August 27 |
| » Defeated Orioles (64-60), 4-1 | Kingdome (34-28) | 56-71 | Won 3 |
| » W: Mike Trujillo (1-0) L: Mike Boddicker (14-8) S: Mark Huismann (5) | Fifth | 14½ out |
| Thursday, August 28 |
| » Lost to Yankees (68-59), 4-2 | Kingdome (34-29) | 56-72 | |
| » W: Dennis Rasmussen (14-4) L: Mike Morgan (9-14) S: Dave Righetti (31) | Fifth | 15½ out |
| Friday, August 29 |
| » Lost to Yankees (69-59), 13-12 | Kingdome (34-30) | 56-73 | Lost 2 |
| » W: Tim Stoddard (4-3) L: Karl Best (2-3) S: Dave Righetti (32) | Fifth | 16½ out |
| Saturday, August 30 |
| » Defeated Yankees (69-60), 1-0 | Kingdome (35-30) | 57-73 | |
| » W: Bill Swift (2-5) L: Tommy John (5-3) S: Matt Young (13) | Fifth | 17 out |
| » Lost to Yankees (70-60), 3-0 | Kingdome (35-31) | 57-74 | |
| » W: Joe Niekro (9-9) L: Mike Brown (4-6) S: Dave Righetti (33) | Fifth | 17 out |
| Sunday, August 31 |
| » Defeated Yankees (70-61), 6-2 | Kingdome (36-31) | 58-74 | |
| » W: Mike Moore (9-11) L: Doug Drabek (3-7) | Fifth | 17 out |
| Monday, September 1 |
| » Lost to Tigers (69-64), 6-5 | Kingdome (36-32) | 58-75 | |
| » W: Jack Morris (16-8) L: Mike Morgan (9-15) | Sixth | 17 out |
| Tuesday, September 2 |
| » Lost to Tigers (70-64), 7-5 | Kingdome (36-33) | 58-76 | Lost 2 |
| » W: Bill Campbell (3-5) L: Lee Guetterman (0-4) S: Jim Slaton (2) | Sixth | 18 out |
| Wednesday, September 3 |
| » Defeated Tigers (70-65), 3-2 | Kingdome (37-33) | 59-76 | |
| » W: Mike Trujillo (2-0) L: Bryan Kelly (0-1) | Sixth | 18 out |
| Friday, September 5 |
| » Defeated Orioles (66-68), 8-2 | Memorial Stadium (2-2) | 60-76 | Won 2 |
| » W: Mike Moore (10-11) L: Ken Dixon (10-11) | Fifth | 17 out |
| Saturday, September 6 |
| » Defeated Orioles (66-69), 6-2 | Memorial Stadium (3-2) | 61-76 | Won 3 |
| » W: Mike Morgan (10-15) L: Mike Boddicker (14-10) | Fifth | 17 out |
| Sunday, September 7 |
| » Lost to Orioles (67-69), 8-0 | Memorial Stadium (3-3) | 61-77 | |
| » W: Scott McGregor (10-11) L: Mark Langston (11-11) | Fifth | 18 out |
| Tuesday, September 9 |
| » Defeated Rangers (71-67), 3-1 | Arlington Stadium (1-4) | 62-77 | |
| » W: Ed Nunez (1-1) L: Jose Guzman (9-14) S: Mike Trujillo (1) | Fourth | 18 out |
| Wednesday, September 10 |
| » Lost to Rangers (72-67), 3-2 | Arlington Stadium (1-5) | 62-78 | |
| » W: Greg Harris (9-8) L: Matt Young (7-6) | Fifth | 19 out |
| Thursday, September 11 |
| » Lost to Royals (66-74), 7-6 | Royals Stadium (2-2) | 62-79 | Lost 2 |
| » W: Dan Quisenberry (2-5) L: Mark Huismann (3-4) | Fifth | 19½ out |
| Friday, September 12 |
| » Defeated Royals (66-75), 4-2 | Royals Stadium (3-2) | 63-79 | |
| » W: Mark Langston (12-11) L: Dan Quisenberry (2-6) | Fifth | 18½ out |
| Saturday, September 13 |
| » Lost to Royals (67-75), 5-4 | Royals Stadium (3-3) | 63-80 | |
| » W: Dennis Leonard (8-11) L: Bill Swift (2-6) S: Buddy Black (7) | Fifth | 19½ out |
| Sunday, September 14 |
| » Lost to Royals (68-75), 10-3 | Royals Stadium (3-4) | 63-81 | Lost 2 |
| » W: Mark Gubicza (10-6) L: Mike Moore (10-12) | Sixth | 19½ out |
| Tuesday, September 16 |
| » Defeated White Sox (63-81), 7-0 | Kingdome (38-33) | 64-81 | |
| » W: Mike Morgan (11-15) L: Richard Dotson (10-15) | Fifth | 20 out |
| Wednesday, September 17 |
| » Lost to White Sox (64-81), 3-0 | Kingdome (38-34) | 64-82 | |
| » W: Floyd Bannister (10-11) L: Mark Langston (12-12) S: Bobby Thigpen (7) | Sixth | 21 out |
| Thursday, September 18 |
| » Lost to White Sox (65-81), 6-4 | Kingdome (38-35) | 64-83 | Lost 2 |
| » W: Steve Carlton (9-13) L: Bill Swift (2-7) S: Gene Nelson (6) | Sixth | 22 out |
| Friday, September 19 |
| » Defeated Royals (68-79), 6-5 | Kingdome (39-35) | 65-83 | |
| » W: Matt Young (8-6) L: Buddy Black (5-9) | Sixth | 21 out |
| » Major-league debuts: Bill Pecota (Royals) |
| Saturday, September 20 |
| » Defeated Royals (68-80), 3-0 | Kingdome (40-35) | 66-83 | Won 2 |
| » W: Mike Trujillo (3-0) L: Bret Saberhagen (6-11) | Sixth | 21 out |
| Sunday, September 21 |
| » Lost to Royals (69-80), 8-1 | Kingdome (40-36) | 66-84 | |
| » W: Charlie Leibrandt (12-11) L: Mike Morgan (11-16) | Sixth | 22 out |
| Monday, September 22 |
| » Lost to Rangers (79-71), 2-0 | Kingdome (40-37) | 66-85 | Lost 2 |
| » W: Ed Correa (11-13) L: Mark Langston (12-13) | Sixth | 22½ out |
| Tuesday, September 23 |
| » Lost to Rangers (80-71), 12-6 | Kingdome (40-38) | 66-86 | Lost 3 |
| » W: Charlie Hough (15-10) L: Bill Swift (2-8) | Sixth | 22½ out |
| Wednesday, September 24 |
| » Defeated Rangers (80-72), 5-4 | Kingdome (41-38) | 67-86 | |
| » W: Mike Moore (11-12) L: Jose Guzman (9-15) S: Pete Ladd (6) | Fifth | 22 out |
| Friday, September 26 |
| » Lost to Indians (78-76), 9-7 | Kingdome (41-39) | 67-87 | |
| » W: Doug Jones (1-0) L: Pete Ladd (8-5) | Fifth | 23½ out |
| Saturday, September 27 |
| » Lost to Indians (79-76), 12-4 | Kingdome (41-40) | 67-88 | Lost 2 |
|