| Monday, April 7 |
| » Major-league debuts: John Kruk (Padres) |
| Tuesday, April 8 |
| » Defeated Astros (0-1), 8-3 | Astrodome (1-0) | 1-0 | |
| » W: Mike Krukow (1-0) L: Nolan Ryan (0-1) S: Mark Davis (1) | First | -- |
| » Major-league debuts: Will Clark and Robby Thompson (Giants) |
| Wednesday, April 9 |
| » Defeated Astros (0-2), 4-1 | Astrodome (2-0) | 2-0 | Won 2 |
| » W: Scott Garrelts (1-0) L: Mike Scott (0-1) S: Greg Minton (1) | First | -- |
| Thursday, April 10 |
| » Lost to Astros (1-2), 4-0 | Astrodome (2-1) | 2-1 | |
| » W: Bob Knepper (1-0) L: Vida Blue (0-1) | First | -- |
| Friday, April 11 |
| » Defeated Dodgers (2-3), 9-8 | Dodger Stadium (1-0) | 3-1 | |
| » W: Jeff Robinson (1-0) L: Tom Niedenfuer (0-1) S: Jim Gott (1) | First | -- |
| Saturday, April 12 |
| » Defeated Dodgers (2-4), 7-6 | Dodger Stadium (2-0) | 4-1 | Won 2 |
| » W: Greg Minton (1-0) L: Dennis Powell (0-1) | First | -- |
| Sunday, April 13 |
| » Lost to Dodgers (3-4), 3-2 | Dodger Stadium (2-1) | 4-2 | |
| » W: Orel Hershiser (1-1) L: Scott Garrelts (1-1) | First | -- |
| Tuesday, April 15 |
| » Lost to Astros (4-3), 8-3 | Candlestick Park (0-1) | 4-3 | Lost 2 |
| » W: Bob Knepper (2-0) L: Vida Blue (0-2) S: Charlie Kerfeld (1) | Second | 1 out |
| Wednesday, April 16 |
| » Lost to Astros (5-3), 4-1 | Candlestick Park (0-2) | 4-4 | Lost 3 |
| » W: Nolan Ryan (2-1) L: Roger Mason (0-1) S: Dave Smith (3) | Fourth | 2 out |
| Thursday, April 17 |
| » Defeated Padres (7-4), 4-1 | Candlestick Park (1-2) | 5-4 | |
| » W: Mike Krukow (2-0) L: Andy Hawkins (0-2) | Fourth | 1 out |
| Friday, April 18 |
| » Defeated Padres (7-5), 6-1 | Candlestick Park (2-2) | 6-4 | Won 2 |
| » W: Scott Garrelts (2-1) L: Mark Thurmond (1-1) | Second | ½ out |
| Saturday, April 19 |
| » Defeated Padres (7-6), 6-5 | Candlestick Park (3-2) | 7-4 | Won 3 |
| » W: Mark Davis (1-0) L: Lance McCullers (1-1) S: Greg Minton (2) | Second | ½ out |
| Sunday, April 20 |
| » Defeated Padres (7-7), 4-0 | Candlestick Park (4-2) | 8-4 | Won 4 |
| » W: Vida Blue (1-2) L: Dave Dravecky (1-1) S: Jeff Robinson (1) | Second | ½ out |
| Monday, April 21 |
| » Defeated Dodgers (4-10), 5-1 | Candlestick Park (5-2) | 9-4 | Won 5 |
| » W: Roger Mason (1-1) L: Rick Honeycutt (0-2) | First | -- |
| Tuesday, April 22 |
| » Defeated Dodgers (4-11), 10-3 | Candlestick Park (6-2) | 10-4 | Won 6 |
| » W: Mike Krukow (3-0) L: Dennis Powell (0-3) | First | -- |
| Wednesday, April 23 |
| » Lost to Dodgers (5-11), 6-4 | Candlestick Park (6-3) | 10-5 | |
| » W: Fernando Valenzuela (2-1) L: Scott Garrelts (2-2) | Second | ½ out |
| Friday, April 25 |
| » Lost to Padres (9-7), 9-8 | San Diego/Jack Murphy Stadium (0-1) | 10-6 | Lost 2 |
| » W: Craig Lefferts (2-0) L: Greg Minton (1-1) | Second | 1 out |
| Saturday, April 26 |
| » Defeated Padres (9-8), 3-2 | San Diego/Jack Murphy Stadium (1-1) | 11-6 | |
| » W: Jeff Robinson (2-0) L: Eric Show (0-2) | Second | 1 out |
| Sunday, April 27 |
| » Lost to Padres (10-8), 6-4 | San Diego/Jack Murphy Stadium (1-2) | 11-7 | |
| » W: Dave Dravecky (2-1) L: Mike Krukow (3-1) S: Rich Gossage (3) | Second | 2 out |
| Monday, April 28 |
| » Lost to Cardinals (8-8), 5-4 | Candlestick Park (6-4) | 11-8 | Lost 2 |
| » W: Todd Worrell (1-1) L: Mark Davis (1-1) S: Pat Perry (1) | Second | 2½ out |
| Tuesday, April 29 |
| » Defeated Cardinals (8-9), 2-0 | Candlestick Park (7-4) | 12-8 | |
| » W: Mike LaCoss (1-0) L: Bob Forsch (1-1) S: Greg Minton (3) | Second | 1½ out |
| Wednesday, April 30 |
| » Defeated Pirates (6-10), 6-5 | Candlestick Park (8-4) | 13-8 | Won 2 |
| » W: Scott Garrelts (3-2) L: Bob Patterson (0-2) | Second | 1½ out |
| Thursday, May 1 |
| » Lost to Pirates (7-10), 6-2 | Candlestick Park (8-5) | 13-9 | |
| » W: Bob Walk (1-0) L: Mike Krukow (3-2) | Second | 2 out |
| Friday, May 2 |
| » Lost to Cubs (8-12), 6-5 | Candlestick Park (8-6) | 13-10 | Lost 2 |
| » W: Matt Keough (2-1) L: Mark Davis (1-2) S: Jay Baller (4) | Second | 3 out |
| Saturday, May 3 |
| » Lost to Cubs (9-12), 6-5 | Candlestick Park (8-7) | 13-11 | Lost 3 |
| » W: George Frazier (1-1) L: Greg Minton (1-2) S: Jay Baller (5) | Second | 3 out |
| Sunday, May 4 |
| » Defeated Cubs (9-13), 2-1 | Candlestick Park (9-7) | 14-11 | |
| » W: Mike LaCoss (2-0) L: Rick Sutcliffe (1-4) | Second | 1½ out |
| » Defeated Cubs (9-14), 2-1 | Candlestick Park (10-7) | 15-11 | Won 2 |
| » W: Roger Mason (2-1) L: George Frazier (1-2) S: Jeff Robinson (2) | Second | 1½ out |
| Former Giant Paul Richards dies in Waxahachie, TX at the age of 78. |
| Tuesday, May 6 |
| » Defeated Pirates (10-11), 7-2 | Three Rivers Stadium (1-0) | 16-11 | Won 3 |
| » W: Mike Krukow (4-2) L: Rick Reuschel (2-3) | Second | 1½ out |
| Wednesday, May 7 |
| » Defeated Pirates (10-12), 7-5 | Three Rivers Stadium (2-0) | 17-11 | Won 4 |
| » W: Bill Laskey (1-0) L: Larry McWilliams (0-3) S: Jeff Robinson (3) | First | -- |
| Thursday, May 8 |
| » Lost to Pirates (11-12), 8-2 | Three Rivers Stadium (2-1) | 17-12 | |
| » W: Mike Bielecki (3-0) L: Scott Garrelts (3-3) | Second | 2 out |
| Friday, May 9 |
| » Defeated Cardinals (11-15), 2-1 | Busch Stadium II (1-0) | 18-12 | |
| » W: Mike LaCoss (3-0) L: Todd Worrell (2-2) S: Mark Davis (2) | Second | 2 out |
| Saturday, May 10 |
| » Lost to Cardinals (12-15), 6-3 | Busch Stadium II (1-1) | 18-13 | |
| » W: Ray Burris (1-0) L: Roger Mason (2-2) S: Ken Dayley (1) | Second | 2 out |
| Sunday, May 11 |
| » Lost to Cardinals (13-15), 4-3 | Busch Stadium II (1-2) | 18-14 | Lost 2 |
| » W: Todd Worrell (3-2) L: Mike Krukow (4-3) | Second | 2 out |
| Tuesday, May 13 |
| » Defeated Cubs (13-17), 6-5 | Wrigley Field (1-0) | 19-14 | |
| » W: Greg Minton (2-2) L: Lee Smith (2-3) S: Bill Laskey (1) | Second | 1½ out |
| Wednesday, May 14 |
| » Defeated Cubs (13-18), 11-3 | Wrigley Field (2-0) | 20-14 | Won 2 |
| » W: Mike LaCoss (4-0) L: Rick Sutcliffe (1-6) | Second | 1½ out |
| Friday, May 16 |
| » Lost to Phillies (14-17), 3-0 | Candlestick Park (10-8) | 20-15 | |
| » W: Steve Carlton (2-5) L: Roger Mason (2-3) S: Kent Tekulve (1) | Second | 1 out |
| Saturday, May 17 |
| » Defeated Phillies (14-18), 12-7 | Candlestick Park (11-8) | 21-15 | |
| » W: Mike Krukow (5-3) L: Shane Rawley (4-4) S: Greg Minton (4) | Second | 1 out |
| Sunday, May 18 |
| » Defeated Phillies (14-19), 4-1 | Candlestick Park (12-8) | 22-15 | Won 2 |
| » W: Scott Garrelts (4-3) L: Freddie Toliver (0-1) S: Jeff Robinson (4) | Second | 1 out |
| Tuesday, May 20 |
| » Lost to Mets (24-9), 2-1 | Candlestick Park (12-9) | 22-16 | |
| » W: Bob Ojeda (6-1) L: Mike LaCoss (4-1) S: Roger McDowell (4) | Second | 1 out |
| Wednesday, May 21 |
| » Lost to Mets (25-9), 7-4 | Candlestick Park (12-10) | 22-17 | Lost 2 |
| » W: Ron Darling (5-0) L: Roger Mason (2-4) | Second | 1 out |
| Thursday, May 22 |
| » Defeated Mets (25-10), 10-2 | Candlestick Park (13-10) | 23-17 | |
| » W: Mike Krukow (6-3) L: Dwight Gooden (5-2) | Second | 1 out |
| Friday, May 23 |
| » Lost to Expos (23-15), 4-3 | Candlestick Park (13-11) | 23-18 | |
| » W: Floyd Youmans (4-3) L: Scott Garrelts (4-4) S: Jeff Reardon (9) | Second | 1 out |
| Saturday, May 24 |
| » Lost to Expos (24-15), 7-4 | Candlestick Park (13-12) | 23-19 | Lost 2 |
| » W: Andy McGaffigan (3-1) L: Vida Blue (1-3) S: Jeff Reardon (10) | Second | 1 out |
| Sunday, May 25 |
| » Defeated Expos (24-16), 11-3 | Candlestick Park (14-12) | 24-19 | |
| » W: Mike LaCoss (5-1) L: Bryn Smith (3-4) | Second | 1 out |
| Tuesday, May 27 |
| » Lost to Phillies (16-24), 6-2 | Veteran's Stadium (0-1) | 24-20 | |
| » W: Steve Carlton (3-6) L: Jeff Robinson (2-1) | Second | 1½ out |
| Wednesday, May 28 |
| » Lost to Phillies (17-24), 4-0 | Veteran's Stadium (0-2) | 24-21 | Lost 2 |
| » W: Shane Rawley (6-4) L: Scott Garrelts (4-5) | Second | 2½ out |
| » Major-league debuts: Mike Aldrete (Giants) |
| Thursday, May 29 |
| » Lost to Phillies (18-24), 5-4 | Veteran's Stadium (0-3) | 24-22 | Lost 3 |
| » W: Don Carman (2-0) L: Greg Minton (2-3) | Third | 3 out |
| Friday, May 30 |
| » Lost to Mets (31-11), 8-7 | Shea Stadium (0-1) | 24-23 | Lost 4 |
| » W: Jesse Orosco (2-2) L: Mark Davis (1-3) | Third | 3 out |
| Saturday, May 31 |
| » Defeated Mets (31-12), 7-3 | Shea Stadium (1-1) | 25-23 | |
| » W: Scott Garrelts (5-5) L: Bob Ojeda (6-2) | Third | 3 out |
| Sunday, June 1 |
| » Defeated Mets (31-13), 7-3 | Shea Stadium (2-1) | 26-23 | Won 2 |
| » W: Mike Krukow (7-3) L: Ron Darling (6-1) | Second | 3 out |
| Tuesday, June 3 |
| » Defeated Expos (26-21), 7-6 | Stade Olympique (1-0) | 27-23 | Won 3 |
| » W: Vida Blue (2-3) L: Floyd Youmans (4-5) S: Mark Davis (3) | Second | 1½ out |
| Wednesday, June 4 |
| » Defeated Expos (26-22), 4-2 | Stade Olympique (2-0) | 28-23 | Won 4 |
| » W: Jeff Robinson (3-1) L: Jeff Reardon (5-3) | Second | 1½ out |
| Thursday, June 5 |
| » Major-league debuts: Manny Hernandez (Astros) |
| Friday, June 6 |
| » Lost to Reds (21-28), 5-3 | Candlestick Park (14-13) | 28-24 | |
| » W: Chris Welsh (1-1) L: Scott Garrelts (5-6) S: Ron Robinson (4) | Second | 1 out |
| Saturday, June 7 |
| » Defeated Reds (21-29), 6-2 | Candlestick Park (15-13) | 29-24 | |
| » W: Mike Krukow (8-3) L: Bill Gullickson (4-6) | Second | 1 out |
| Sunday, June 8 |
| » Lost to Reds (22-29), 7-3 | Candlestick Park (15-14) | 29-25 | |
| » W: John Denny (4-5) L: Mike LaCoss (5-2) | Second | 1½ out |
| » Defeated Reds (22-30), 3-1 | Candlestick Park (16-14) | 30-25 | |
| » W: Jeff Robinson (4-1) L: Ted Power (3-4) | Second | 1½ out |
| » Major-league debuts: Terry Mulholland (Giants) |
| Tuesday, June 10 |
| » Defeated Braves (28-28), 3-0 | Candlestick Park (17-14) | 31-25 | Won 2 |
| » W: Vida Blue (3-3) L: Zane Smith (5-6) S: Jeff Robinson (5) | Second | 2 out |
| Wednesday, June 11 |
| » Lost to Braves (29-28), 2-1 | Candlestick Park (17-15) | 31-26 | |
| » W: Gene Garber (2-1) L: Greg Minton (2-4) | Second | 2 out |
| Thursday, June 12 |
| » Lost to Astros (34-24), 4-1 | Astrodome (2-2) | 31-27 | Lost 2 |
| » W: Manny Hernandez (1-1) L: Mike Krukow (8-4) S: Dave Smith (16) | Second | 3 out |
| Friday, June 13 |
| » Defeated Astros (34-25), 3-1 | Astrodome (3-2) | 32-27 | |
| » W: Mark Davis (2-3) L: Mike Scott (6-5) | Second | 2 out |
| Saturday, June 14 |
| » Lost to Astros (35-25), 7-3 | Astrodome (3-3) | 32-28 | |
| » W: Jim Deshaies (3-2) L: Terry Mulholland (0-1) S: Aurelio Lopez (2) | Second | 3 out |
| Sunday, June 15 |
| » Defeated Astros (35-26), 7-2 | Astrodome (4-3) | 33-28 | |
| » W: Vida Blue (4-3) L: Bob Knepper (10-4) | Second | 2 out |
| Monday, June 16 |
| » Lost to Padres (30-32), 4-0 | San Diego/Jack Murphy Stadium (1-3) | 33-29 | |
| » W: Andy Hawkins (5-4) L: Bill Laskey (1-1) | Second | 2½ out |
| Tuesday, June 17 |
| » Lost to Padres (31-32), 8-5 | San Diego/Jack Murphy Stadium (1-4) | 33-30 | Lost 2 |
| » W: Craig Lefferts (4-2) L: Jeff Robinson (4-2) S: Rich Gossage (10) | Second | 2½ out |
| Wednesday, June 18 |
| » Defeated Padres (31-33), 6-3 | San Diego/Jack Murphy Stadium (2-4) | 34-30 | |
| » W: Mike LaCoss (6-2) L: Mark Thurmond (3-6) S: Juan Berenguer (1) | Second | 1½ out |
| Thursday, June 19 |
| » Lost to Padres (32-33), 8-3 | San Diego/Jack Murphy Stadium (2-5) | 34-31 | |
| » W: Eric Show (5-4) L: Terry Mulholland (0-2) | Second | 2½ out |
| » Major-league debuts: Randy Kutcher (Giants) |
| Friday, June 20 |
| » Defeated Astros (36-29), 3-1 | Candlestick Park (18-15) | 35-31 | |
| » W: Vida Blue (5-3) L: Bob Knepper (10-5) S: Juan Berenguer (2) | Second | 1½ out |
| Saturday, June 21 |
| » Defeated Astros (36-30), 2-1 | Candlestick Park (19-15) | 36-31 | Won 2 |
| » W: Scott Garrelts (6-6) L: Mark Knudson (0-1) S: Juan Berenguer (3) | Second | ½ out |
| Sunday, June 22 |
| » Defeated Astros (36-31), 4-2 | Candlestick Park (20-15) | 37-31 | Won 3 |
| » W: Mike Krukow (9-4) L: Manny Hernandez (1-3) | First | -- |
| » Defeated Astros (36-32), 3-2 | Candlestick Park (21-15) | 38-31 | Won 4 |
| » W: Juan Berenguer (1-0) L: Dave Smith (1-4) S: Chuck Hensley (1) | First | -- |
| Monday, June 23 |
| » Defeated Padres (35-34), 18-1 | Candlestick Park (22-15) | 39-31 | Won 5 |
| » W: Mike LaCoss (7-2) L: LaMarr Hoyt (2-4) | First | -- |
| Tuesday, June 24 |
| » Lost to Padres (36-34), 3-0 | Candlestick Park (22-16) | 39-32 | |
| » W: Eric Show (6-4) L: Terry Mulholland (0-3) S: Rich Gossage (12) | First | -- |
| Wednesday, June 25 |
| » Lost to Padres (37-34), 3-1 | Candlestick Park (22-17) | 39-33 | Lost 2 |
| » W: Dave Dravecky (6-7) L: Vida Blue (5-4) S: Rich Gossage (13) | First | -- |
| Friday, June 27 |
| » Defeated Reds (30-40), 7-6 | Riverfront Stadium (1-0) | 40-33 | |
| » W: Greg Minton (3-4) L: Scott Terry (0-2) | First | -- |
| Saturday, June 28 |
| » Defeated Reds (30-41), 5-1 | Riverfront Stadium (2-0) | 41-33 | Won 2 |
| » W: Frank Williams (1-0) L: John Denny (5-7) | First | -- |
| Sunday, June 29 |
| » Lost to Reds (31-41), 4-3 | Riverfront Stadium (2-1) | 41-34 | |
| » W: Ron Robinson (6-0) L: Mike LaCoss (7-3) | Second | ½ out |
| Monday, June 30 |
| » Lost to Braves (39-36), 5-1 | Atlanta-Fulton County Stadium (0-1) | 41-35 | Lost 2 |
| » W: Rick Mahler (10-5) L: Mark Davis (2-4) | Second | ½ out |
| Tuesday, July 1 |
| » Defeated Braves (39-37), 9-6 | Atlanta-Fulton County Stadium (1-1) | 42-35 | |
| » W: Jeff Robinson (5-2) L: Joe Johnson (6-7) | First | -- |
| Wednesday, July 2 |
| » Lost to Braves (40-37), 7-4 | Atlanta-Fulton County Stadium (1-2) | 42-36 | |
| » W: Zane Smith (7-8) L: Scott Garrelts (6-7) | Second | ½ out |
| Thursday, July 3 |
| » Defeated Cardinals (32-44), 1-0 | Candlestick Park (23-17) | 43-36 | |
| » W: Mike Krukow (10-4) L: Rick Ownbey (1-3) | First | -- |
| Friday, July 4 |
| » Defeated Cardinals (32-45), 6-1 | Candlestick Park (24-17) | 44-36 | Won 2 |
| » W: Mike LaCoss (8-3) L: Ray Burris (4-4) | First | -- |
| Saturday, July 5 |
| » Lost to Cardinals (33-45), 7-4 | Candlestick Park (24-18) | 44-37 | |
| » W: Todd Worrell (6-8) L: Juan Berenguer (1-1) S: Ken Dayley (5) | First | -- |
| Sunday, July 6 |
| » Defeated Cardinals (33-46), 8-3 | Candlestick Park (25-18) | 45-37 | |
| » W: Scott Garrelts (7-7) L: Danny Cox (2-7) | First | -- |
| Tuesday, July 8 |
| » Lost to Cubs (33-46), 4-1 | Candlestick Park (25-19) | 45-38 | |
| » W: Dennis Eckersley (3-5) L: Mike Krukow (10-5) | First | -- |
| Wednesday, July 9 |
| » Lost to Cubs (34-46), 4-3 | Candlestick Park (25-20) | 45-39 | Lost 2 |
| » W: Lee Smith (6-6) L: Juan Berenguer (1-2) S: Ray Fontenot (2) | First | -- |
| Former Giant Red Lucas dies in Nashville, TN at the age of 85. |
| Thursday, July 10 |
| » Defeated Pirates (34-48), 6-3 | Candlestick Park (26-20) | 46-39 | |
| » W: Vida Blue (6-4) L: Bob Walk (4-5) S: Scott Garrelts (1) | First | -- |
| Friday, July 11 |
| » Lost to Pirates (35-48), 8-4 | Candlestick Park (26-21) | 46-40 | |
| » W: Jim Winn (2-3) L: Steve Carlton (4-9) S: Don Robinson (3) | First | -- |
| Saturday, July 12 |
| » Defeated Pirates (35-49), 3-1 | Candlestick Park (27-21) | 47-40 | |
| » W: Mike Krukow (11-5) L: Rick Rhoden (9-5) | First | -- |
| Sunday, July 13 |
| » Defeated Pirates (35-50), 11-4 | Candlestick Park (28-21) | 48-40 | Won 2 |
| » W: Mike LaCoss (9-3) L: Rick Reuschel (4-11) | First | -- |
| Thursday, July 17 |
| » Defeated Cubs (36-49), 6-4 | Wrigley Field (3-0) | 49-40 | Won 3 |
| » W: Vida Blue (7-4) L: Ed Lynch (1-1) | First | -- |
| Friday, July 18 |
| » Lost to Cubs (37-49), 2-1 | Wrigley Field (3-1) | 49-41 | |
| » W: Scott Sanderson (5-6) L: Mike LaCoss (9-4) S: Lee Smith (15) | First | -- |
| Saturday, July 19 |
| » Lost to Cubs (38-49), 11-6 | Wrigley Field (3-2) | 49-42 | Lost 2 |
| » W: Guy Hoffman (4-2) L: Mike Krukow (11-6) S: Dave Gumpert (2) | First | -- |
| Sunday, July 20 |
| » Defeated Cubs (38-50), 5-4 | Wrigley Field (4-2) | 50-42 | |
| » W: Scott Garrelts (8-7) L: Dennis Eckersley (3-6) | First | -- |
| Monday, July 21 |
| » Lost to Cardinals (39-52), 8-3 | Busch Stadium II (1-3) | 50-43 | |
| » W: Greg Mathews (5-2) L: Steve Carlton (4-10) | Second | 1 out |
| Tuesday, July 22 |
| » Lost to Cardinals (40-52), 10-7 | Busch Stadium II (1-4) | 50-44 | Lost 2 |
| » W: John Tudor (8-5) L: Vida Blue (7-5) S: Todd Worrell (17) | Second | 2 out |
| Wednesday, July 23 |
| » Lost to Cardinals (41-52), 4-3 | Busch Stadium II (1-5) | 50-45 | Lost 3 |
| » W: Danny Cox (4-8) L: Mike LaCoss (9-5) S: Todd Worrell (18) | Second | 3 out |
| Friday, July 25 |
| » Defeated Pirates (38-55), 7-3 | Three Rivers Stadium (3-1) | 51-45 | |
| » W: Roger Mason (3-4) L: Mike Bielecki (6-6) S: Jeff Robinson (6) | Second | 2½ out |
| Saturday, July 26 |
| » Defeated Pirates (38-56), 9-0 | Three Rivers Stadium (4-1) | 52-45 | Won 2 |
| » W: Steve Carlton (5-10) L: Larry McWilliams (2-6) | Second | 1½ out |
| Sunday, July 27 |
| » Lost to Pirates (39-56), 7-0 | Three Rivers Stadium (4-2) | 52-46 | |
| » W: Rick Rhoden (10-6) L: Vida Blue (7-6) S: Don Robinson (5) | Second | 2½ out |
| Monday, July 28 |
| » Lost to Dodgers (47-52), 2-1 | Dodger Stadium (2-2) | 52-47 | Lost 2 |
| » W: Orel Hershiser (10-7) L: Mike LaCoss (9-6) | Second | 3½ out |
| Former Giant Cliff Melton dies in Baltimore, MD at the age of 75. Former Giant Joe Oeschger dies in Rohnert Park, CA at the age of 95. |
| Tuesday, July 29 |
| » Lost to Dodgers (48-52), 2-1 | Dodger Stadium (2-3) | 52-48 | Lost 3 |
| » W: Fernando Valenzuela (14-6) L: Kelly Downs (0-1) | Second | 3½ out |
| » Major-league debuts: Kelly Downs (Giants) |
| Wednesday, July 30 |
| » Lost to Dodgers (49-52), 4-2 | Dodger Stadium (2-4) | 52-49 | Lost 4 |
| » W: Bob Welch (5-9) L: Terry Mulholland (0-4) S: Tom Niedenfuer (6) | Second | 4½ out |
| Thursday, July 31 |
| » Defeated Braves (46-55), 3-2 | Candlestick Park (29-21) | 53-49 | |
| » W: Scott Garrelts (9-7) L: Gene Garber (4-2) | Second | 4 out |
| Friday, August 1 |
| » Defeated Braves (46-56), 3-1 | Candlestick Park (30-21) | 54-49 | Won 2 |
| » W: Vida Blue (8-6) L: Rick Mahler (10-11) S: Scott Garrelts (2) | Second | 4 out |
| Saturday, August 2 |
| » Defeated Braves (46-57), 7-5 | Candlestick Park (31-21) | 55-49 | Won 3 |
| » W: Frank Williams (2-0) L: Doyle Alexander (6-8) S: Juan Berenguer (4) | Second | 4 out |
| Sunday, August 3 |
| » Lost to Braves (47-57), 4-2 | Candlestick Park (31-22) | 55-50 | |
| » W: David Palmer (8-8) L: Kelly Downs (0-2) S: Gene Garber (14) | Second | 4 out |
| Monday, August 4 |
| » Lost to Reds (48-55), 2-1 | Candlestick Park (31-23) | 55-51 | Lost 2 |
| » W: John Denny (8-10) L: Terry Mulholland (0-5) S: John Franco (17) | Second | 4 out |
| Tuesday, August 5 |
| » Lost to Reds (49-55), 11-6 | Candlestick Park (31-24) | 55-52 | Lost 3 |
| » W: Mario Soto (4-9) L: Steve Carlton (5-11) | Second | 5 out |
| Wednesday, August 6 |
| » Defeated Reds (49-56), 2-1 | Candlestick Park (32-24) | 56-52 | |
| » W: Jeff Robinson (6-2) L: Carl Willis (1-3) | Second | 4 out |
| Friday, August 8 |
| » Lost to Braves (51-57), 7-6 | Atlanta-Fulton County Stadium (1-3) | 56-53 | |
| » W: Doyle Alexander (7-8) L: Mike LaCoss (9-7) S: Gene Garber (17) | Second | 5 out |
| Saturday, August 9 |
| » Defeated Braves (51-58), 4-3 | Atlanta-Fulton County Stadium (2-3) | 57-53 | |
| » W: Scott Garrelts (10-7) L: Jeff Dedmon (3-6) | Second | 5 out |
| Sunday, August 10 |
| » Defeated Braves (51-59), 4-3 | Atlanta-Fulton County Stadium (3-3) | 58-53 | Won 2 |
| » W: Juan Berenguer (2-2) L: Gene Garber (4-3) S: Scott Garrelts (3) | Second | 4 out |
| Monday, August 11 |
| » Defeated Reds (52-58), 13-4 | Riverfront Stadium (3-1) | 59-53 | Won 3 |
| » W: Mark Davis (3-4) L: Tom Browning (9-9) S: Frank Williams (1) | Second | 4 out |
| Former Giant Tom Gorman dies in Closter, NJ at the age of 71. |
| Tuesday, August 12 |
| » Defeated Reds (52-59), 2-1 | Riverfront Stadium (4-1) | 60-53 | Won 4 |
| » W: Vida Blue (9-6) L: Bill Gullickson (8-8) S: Scott Garrelts (4) | Second | 4 out |
| Wednesday, August 13 |
| » Lost to Reds (53-59), 8-6 | Riverfront Stadium (4-2) | 60-54 | |
| » W: John Franco (4-4) L: Scott Garrelts (10-8) S: Ron Robinson (9) | Second | 4 out |
| » Major-league debuts: Barry Larkin (Reds) |
| Thursday, August 14 |
| » Lost to Reds (54-59), 2-0 | Riverfront Stadium (4-3) | 60-55 | Lost 2 |
| » W: John Denny (10-10) L: Kelly Downs (0-3) | Second | 5 out |
| Friday, August 15 |
| » Defeated Dodgers (56-60), 5-1 | Candlestick Park (33-24) | 61-55 | |
| » W: Mike Krukow (12-6) L: Dennis Powell (2-4) | Second | 5 out |
| Saturday, August 16 |
| » Lost to Dodgers (57-60), 6-5 | Candlestick Park (33-25) | 61-56 | |
| » W: Bob Welch (6-9) L: Mike LaCoss (9-8) S: Tom Niedenfuer (9) | Second | 6 out |
| Sunday, August 17 |
| » Lost to Dodgers (58-60), 2-0 | Candlestick Park (33-26) | 61-57 | Lost 2 |
| » W: Rick Honeycutt (9-7) L: Vida Blue (9-7) S: Tom Niedenfuer (10) | Second | 6 out |
| Tuesday, August 19 |
| » Lost to Phillies (60-59), 6-5 | Candlestick Park (33-27) | 61-58 | Lost 3 |
| » W: Kent Tekulve (6-1) L: Scott Garrelts (10-9) S: Steve Bedrosian (16) | Second | 7½ out |
| Wednesday, August 20 |
| » Lost to Phillies (61-59), 1-0 | Candlestick Park (33-28) | 61-59 | Lost 4 |
| » W: Don Carman (6-4) L: Mike Krukow (12-7) S: Steve Bedrosian (17) | Second | 7½ out |
| Thursday, August 21 |
| » Defeated Phillies (61-60), 7-6 | Candlestick Park (34-28) | 62-59 | |
| » W: Mark Davis (4-4) L: Kent Tekulve (6-2) S: Scott Garrelts (5) | Second | 7 out |
| Friday, August 22 |
| » Lost to Mets (81-41), 5-3 | Candlestick Park (34-29) | 62-60 | |
| » W: Dwight Gooden (13-4) L: Vida Blue (9-8) S: Roger McDowell (15) | Second | 7 out |
| Saturday, August 23 |
| » Lost to Mets (82-41), 3-2 | Candlestick Park (34-30) | 62-61 | Lost 2 |
| » W: Bob Ojeda (14-4) L: Kelly Downs (0-4) S: Roger McDowell (16) | Second | 7 out |
| Sunday, August 24 |
| » Defeated Mets (82-42), 10-1 | Candlestick Park (35-30) | 63-61 | |
| » W: Mike Krukow (13-7) L: Rick Aguilera (6-6) | Second | 7 out |
| Monday, August 25 |
| » Lost to Expos (61-61), 6-5 | Candlestick Park (35-31) | 63-62 | |
| » W: Andy McGaffigan (8-4) L: Mike LaCoss (9-9) S: Jeff Reardon (28) | Second | 8 out |
| Tuesday, August 26 |
| » Defeated Expos (61-62), 1-0 | Candlestick Park (36-31) | 64-62 | |
| » W: Scott Garrelts (11-9) L: Bert Roberge (0-3) | Second | 7 out |
| Wednesday, August 27 |
| » Defeated Expos (61-63), 3-2 | Candlestick Park (37-31) | 65-62 | Won 2 |
| » W: Kelly Downs (1-4) L: Andy McGaffigan (8-5) S: Scott Garrelts (6) | Second | 7 out |
| Friday, August 29 |
| » Lost to Phillies (66-62), 6-4 | Veteran's Stadium (0-4) | 65-63 | |
| » W: Mike Maddux (2-5) L: Mike Krukow (13-8) S: Steve Bedrosian (20) | Third | 8 out |
| Saturday, August 30 |
| » Lost to Phillies (67-62), 5-3 | Veteran's Stadium (0-5) | 65-64 | Lost 2 |
| » W: Don Carman (7-5) L: Mike LaCoss (9-10) S: Steve Bedrosian (21) | Third | 8 out |
| Sunday, August 31 |
| » Lost to Phillies (68-62), 4-3 | Veteran's Stadium (0-6) | 65-65 | Lost 3 |
| » W: Kent Tekulve (8-3) L: Vida Blue (9-9) S: Steve Bedrosian (22) | Third | 8 out |
| Monday, September 1 |
| » Lost to Mets (88-43), 5-2 | Shea Stadium (2-2) | 65-66 | Lost 4 |
| » W: Roger McDowell (13-7) L: Mark Davis (4-5) | Third | 9 out |
| Tuesday, September 2 |
| » Defeated Mets (88-44), 4-3 | Shea Stadium (3-2) | 66-66 | |
| » W: Mike Krukow (14-8) L: Dwight Gooden (13-5) S: Scott Garrelts (7) | Third | 8½ out |
| » Major-league debuts: Kevin Elster (Mets) |
| Wednesday, September 3 |
| » Lost to Mets (89-44), 4-2 | Shea Stadium (3-3) | 66-67 | |
| » W: Bob Ojeda (16-4) L: Terry Mulholland (0-6) | Third | 10 out |
| Thursday, September 4 |
| » Lost to Expos (65-66), 4-2 | Stade Olympique (2-1) | 66-68 | Lost 2 |
| » W: Bryn Smith (10-8) L: Mike LaCoss (9-11) S: Jeff Reardon (29) | Third | 10½ out |
| Friday, September 5 |
| » Defeated Expos (65-67), 8-4 | Stade Olympique (3-1) | 67-68 | |
| » W: Scott Garrelts (12-9) L: Tim Burke (8-7) | Third | 9½ out |
| Saturday, September 6 |
| » Lost to Expos (66-67), 3-1 | Stade Olympique (3-2) | 67-69 | |
| » W: Bob McClure (3-4) L: Frank Williams (2-1) S: Jeff Reardon (30) | Third | 10½ out |
| Sunday, September 7 |
| » Defeated Expos (66-68), 1-0 | Stade Olympique (4-2) | 68-69 | |
| » W: Mike Krukow (15-8) L: Floyd Youmans (12-10) | Third | 10½ out |
| Monday, September 8 |
| » Defeated Padres (63-75), 4-3 | Candlestick Park (38-31) | 69-69 | Won 2 |
| » W: Terry Mulholland (1-6) L: Ed Whitson (6-9) S: Scott Garrelts (8) | Third | 10½ out |
| Tuesday, September 9 |
| » Defeated Padres (63-76), 7-0 | Candlestick Park (39-31) | 70-69 | Won 3 |
| » W: Mike LaCoss (10-11) L: LaMarr Hoyt (7-10) | Third | 10½ out |
| Wednesday, September 10 |
| » Lost to Reds (71-68), 14-2 | Candlestick Park (39-32) | 70-70 | |
| » W: Ted Power (7-6) L: Vida Blue (9-10) | Third | 10½ out |
| Thursday, September 11 |
| » Defeated Reds (71-69), 2-1 | Candlestick Park (40-32) | 71-70 | |
| » W: Kelly Downs (2-4) L: Bill Gullickson (13-10) S: Scott Garrelts (9) | Third | 9½ out |
| Friday, September 12 |
| » Defeated Braves (64-76), 11-2 | Candlestick Park (41-32) | 72-70 | Won 2 |
| » W: Mike Krukow (16-8) L: Jim Acker (5-9) | Third | 9½ out |
| Saturday, September 13 |
| » Lost to Braves (65-76), 4-1 | Candlestick Park (41-33) | 72-71 | |
| » W: Rick Mahler (13-15) L: Terry Mulholland (1-7) | Third | 9½ out |
| Sunday, September 14 |
| » Defeated Braves (65-77), 7-6 | Candlestick Park (42-33) | 73-71 | |
| » W: Scott Garrelts (13-9) L: Paul Assenmacher (6-3) | Third | 8½ out |
| Tuesday, September 16 |
| » Defeated Padres (67-78), 4-1 | San Diego/Jack Murphy Stadium (3-5) | 74-71 | Won 2 |
| » W: Mike Krukow (17-8) L: Ed Wojna (2-1) S: Mark Davis (4) | Third | 8½ out |
| Wednesday, September 17 |
| » Lost to Padres (68-78), 5-4 | San Diego/Jack Murphy Stadium (3-6) | 74-72 | |
| » W: Lance McCullers (9-8) L: Mark Davis (4-6) | Third | 9½ out |
| » Major-league debuts: Ed Vosberg (Padres) |
| Friday, September 19 |
| » Defeated Braves (68-78), 4-0 | Atlanta-Fulton County Stadium (4-3) | 75-72 | |
| » W: Kelly Downs (3-4) L: Rick Mahler (13-16) S: Jeff Robinson (7) | Second | 10 out |
| Saturday, September 20 |
| » Lost to Braves (69-78), 2-1 | Atlanta-Fulton County Stadium (4-4) | 75-73 | |
| » W: Charlie Puleo (1-0) L: Mike LaCoss (10-12) | Second | 11 out |
| Sunday, September 21 |
| » Defeated Braves (69-79), 8-2 | Atlanta-Fulton County Stadium (5-4) | 76-73 | |
| » W: Mike Krukow (18-8) L: Doyle Alexander (10-10) | Second | 10 out |
| Monday, September 22 |
| » Defeated Reds (76-74), 10-7 | Riverfront Stadium (5-3) | 77-73 | Won 2 |
| » W: Frank Williams (3-1) L: Chris Welsh (6-8) S: Greg Minton (5) | Second | 9 out |
| Tuesday, September 23 |
| » Lost to Reds (77-74), 6-5 | Riverfront Stadium (5-4) | 77-74 | |
| » W: Tom Browning (14-13) L: Mark Davis (4-7) S: Ron Robinson (11) | Second | 10 out |
| Wednesday, September 24 |
| » Lost to Astros (88-64), 6-0 | Astrodome (4-4) | 77-75 | Lost 2 |
| » W: Nolan Ryan (11-8) L: Mike LaCoss (10-13) | Third | 11 out |
| Thursday, September 25 |
| » Lost to Astros (89-64), 2-0 | Astrodome (4-5) | 77-76 | Lost 3 |
| » W: Mike Scott (18-10) L: Juan Berenguer (2-3) | Third | 12 out |
| Friday, September 26 |
| » Defeated Dodgers (71-83), 3-0 | Candlestick Park (43-33) | 78-76 | |
| » W: Mike Krukow (19-8) L: Tom Niedenfuer (6-6) S: Scott Garrelts (10) | Third | 11 out |
| Saturday, September 27 |
| » Defeated Dodgers (71-84), 8-3 | Candlestick Park (44-33) | 79-76 | Won 2 |
| » W: Vida Blue (10-10) L: Fernando Valenzuela (20-11) S: Jeff Robinson (8) | Third | 11 out |
| Sunday, September 28 |
| » Defeated Dodgers (71-85), 6-5 | Candlestick Park (45-33) | 80-76 | Won 3 |
| » W: Greg Minton (4-4) L: Balvino Galvez (0-1) | Third | 11 out |
| Tuesday, September 30 |
| » Defeated Astros (91-66), 6-5 | Candlestick Park (46-33) | 81-76 | Won 4 |
| » W: Mark Davis (5-7) L: Aurelio Lopez (3-3) | Third | 10 out |
| Wednesday, October 1 |
| » Lost to Astros (92-66), 5-0 | Candlestick Park (46-34) | 81-77 | |
| » W: Danny Darwin (11-10) L: Mike Krukow (19-9) | Third | 11 out |
| Thursday, October 2 |
| » Lost to Astros (93-66), 2-1 | Candlestick Park (46-35) | 81-78 | Lost 2 |
| » W: Matt Keough (5-4) L: Jeff Robinson (6-3) S: Dave Smith (33) | Third | 12 out |
| Friday, October 3 |
| » Defeated Dodgers (72-88), 8-2 | Dodger Stadium (3-4) | 82-78 | |
| » W: Kelly Downs (4-4) L: Bob Welch (7-13) | Third | 12 out |
| Former Giant Vince DiMaggio dies in N.Hollywood, CA at the age of 75. |
| Saturday, October 4 |
| » Lost to Dodgers (73-88), 2-1 | Dodger Stadium (3-5) | 82-79 | |
| » W: Fernando Valenzuela (21-11) L: Mark Grant (0-1) | Third | 13 out |
| Sunday, October 5 |
| » Defeated Dodgers (73-89), 11-2 | Dodger Stadium (4-5) | 83-79 | |
| » W: Mike Krukow (20-9) L: Orel Hershiser (14-14) | Third | 13 out |
| Wednesday, October 8 |
| Former Giant Max Surkont dies in Largo, FL at the age of 65. |
Game information provided by Retrosheet (www.retrosheet.org) |