| Sunday, January 12 |
| Former Cardinal Eddie Solomon dies in Macon, GA at the age of 35. |
| Tuesday, February 25 |
| Former Cardinal George Susce dies in Sarasota, FL at the age of 79. |
| Monday, April 7 |
| » Major-league debuts: John Kruk (Padres) |
| Tuesday, April 8 |
| » Defeated Cubs (0-1), 2-1 | Busch Stadium II (1-0) | 1-0 | |
| » W: John Tudor (1-0) L: Rick Sutcliffe (0-1) | First | -- |
| Thursday, April 10 |
| » Defeated Cubs (0-2), 4-2 | Busch Stadium II (2-0) | 2-0 | Won 2 |
| » W: Rick Ownbey (1-0) L: Dennis Eckersley (0-1) S: Todd Worrell (1) | First | -- |
| Friday, April 11 |
| » Defeated Expos (1-2), 9-1 | Busch Stadium II (3-0) | 3-0 | Won 3 |
| » W: Bob Forsch (1-0) L: Joe Hesketh (0-1) | First | -- |
| » Major-league debuts: Jeff Parrett (Expos) |
| Saturday, April 12 |
| » Defeated Expos (1-3), 6-3 | Busch Stadium II (4-0) | 4-0 | Won 4 |
| » W: John Tudor (2-0) L: Floyd Youmans (0-1) S: Todd Worrell (2) | First | -- |
| Sunday, April 13 |
| » Lost to Expos (2-3), 3-2 | Busch Stadium II (4-1) | 4-1 | |
| » W: Bryn Smith (1-1) L: Kurt Kepshire (0-1) S: Jeff Reardon (1) | First | -- |
| Monday, April 14 |
| » Defeated Mets (2-3), 6-2 | Shea Stadium (1-0) | 5-1 | |
| » W: Pat Perry (1-0) L: Randy Niemann (0-2) | First | -- |
| Friday, April 18 |
| » Defeated Expos (3-5), 4-2 | Stade Olympique (1-0) | 6-1 | Won 2 |
| » W: John Tudor (3-0) L: Joe Hesketh (0-2) S: Todd Worrell (3) | First | -- |
| Saturday, April 19 |
| » Defeated Expos (3-6), 9-6 | Stade Olympique (2-0) | 7-1 | Won 3 |
| » W: Tim Conroy (1-0) L: Floyd Youmans (0-2) | First | -- |
| Sunday, April 20 |
| » Lost to Expos (4-6), 2-0 | Stade Olympique (2-1) | 7-2 | |
| » W: Jay Tibbs (2-0) L: Ricky Horton (0-1) | First | -- |
| Tuesday, April 22 |
| » Lost to Cubs (3-7), 3-2 | Wrigley Field (0-1) | 7-3 | Lost 2 |
| » W: Jay Baller (1-0) L: Pat Perry (1-1) | First | -- |
| Wednesday, April 23 |
| » Lost to Cubs (4-7), 6-0 | Wrigley Field (0-2) | 7-4 | Lost 3 |
| » W: Scott Sanderson (1-1) L: Rick Ownbey (1-1) | Second | ½ out |
| Thursday, April 24 |
| » Lost to Mets (8-3), 5-4 | Busch Stadium II (4-2) | 7-5 | Lost 4 |
| » W: Roger McDowell (2-0) L: Todd Worrell (0-1) | Second | 1½ out |
| Friday, April 25 |
| » Lost to Mets (9-3), 9-0 | Busch Stadium II (4-3) | 7-6 | Lost 5 |
| » W: Dwight Gooden (3-0) L: Ricky Horton (0-2) | Second | 2½ out |
| Saturday, April 26 |
| » Lost to Mets (10-3), 4-3 | Busch Stadium II (4-4) | 7-7 | Lost 6 |
| » W: Sid Fernandez (2-0) L: Danny Cox (0-1) S: Jesse Orosco (3) | Second | 3½ out |
| Sunday, April 27 |
| » Lost to Mets (11-3), 5-3 | Busch Stadium II (4-5) | 7-8 | Lost 7 |
| » W: Bob Ojeda (3-0) L: John Tudor (3-1) | Second | 4½ out |
| Monday, April 28 |
| » Defeated Giants (11-8), 5-4 | Candlestick Park (1-0) | 8-8 | |
| » W: Todd Worrell (1-1) L: Mark Davis (1-1) S: Pat Perry (1) | Second | 4 out |
| Tuesday, April 29 |
| » Lost to Giants (12-8), 2-0 | Candlestick Park (1-1) | 8-9 | |
| » W: Mike LaCoss (1-0) L: Bob Forsch (1-1) S: Greg Minton (3) | Third | 5 out |
| Wednesday, April 30 |
| » Lost to Padres (12-9), 5-0 | San Diego/Jack Murphy Stadium (0-1) | 8-10 | Lost 2 |
| » W: Mark Thurmond (2-1) L: Ricky Horton (0-3) | Fourth | 6 out |
| Thursday, May 1 |
| » Lost to Padres (13-9), 4-3 | San Diego/Jack Murphy Stadium (0-2) | 8-11 | Lost 3 |
| » W: Eric Show (1-2) L: Danny Cox (0-2) S: Rich Gossage (4) | Fourth | 6 out |
| Friday, May 2 |
| » Lost to Dodgers (12-13), 3-2 | Dodger Stadium (0-1) | 8-12 | Lost 4 |
| » W: Jerry Reuss (2-0) L: John Tudor (3-2) S: Ken Howell (2) | Fourth | 7 out |
| Saturday, May 3 |
| » Lost to Dodgers (13-13), 3-0 | Dodger Stadium (0-2) | 8-13 | Lost 5 |
| » W: Fernando Valenzuela (4-1) L: Tim Conroy (1-1) | Sixth | 8 out |
| Sunday, May 4 |
| » Defeated Dodgers (13-14), 3-1 | Dodger Stadium (1-2) | 9-13 | |
| » W: Bob Forsch (2-1) L: Orel Hershiser (3-3) S: Todd Worrell (4) | Fifth | 8 out |
| Tuesday, May 6 |
| » Lost to Padres (14-12), 3-2 | Busch Stadium II (4-6) | 9-14 | |
| » W: Gene Walter (1-0) L: Ken Dayley (0-1) S: Rich Gossage (5) | Sixth | 9 out |
| Wednesday, May 7 |
| » Defeated Padres (14-13), 4-3 | Busch Stadium II (5-6) | 10-14 | |
| » W: Todd Worrell (2-1) L: Rich Gossage (2-3) | Fourth | 9 out |
| Thursday, May 8 |
| » Defeated Padres (14-14), 13-3 | Busch Stadium II (6-6) | 11-14 | Won 2 |
| » W: Tim Conroy (2-1) L: Dave Dravecky (2-3) | Fourth | 8½ out |
| Friday, May 9 |
| » Lost to Giants (18-12), 2-1 | Busch Stadium II (6-7) | 11-15 | |
| » W: Mike LaCoss (3-0) L: Todd Worrell (2-2) S: Mark Davis (2) | Fourth | 9½ out |
| Saturday, May 10 |
| » Defeated Giants (18-13), 6-3 | Busch Stadium II (7-7) | 12-15 | |
| » W: Ray Burris (1-0) L: Roger Mason (2-2) S: Ken Dayley (1) | Third | 9½ out |
| Sunday, May 11 |
| » Defeated Giants (18-14), 4-3 | Busch Stadium II (8-7) | 13-15 | Won 2 |
| » W: Todd Worrell (3-2) L: Mike Krukow (4-3) | Third | 8½ out |
| Tuesday, May 13 |
| » Lost to Dodgers (15-19), 6-5 | Busch Stadium II (8-8) | 13-16 | |
| » W: Rick Honeycutt (2-2) L: Ken Dayley (0-2) | Third | 9 out |
| Wednesday, May 14 |
| » Lost to Dodgers (16-19), 8-3 | Busch Stadium II (8-9) | 13-17 | Lost 2 |
| » W: Fernando Valenzuela (5-2) L: Tim Conroy (2-2) | Fourth | 9 out |
| Friday, May 16 |
| » Lost to Braves (16-18), 6-2 | Atlanta-Fulton County Stadium (0-1) | 13-18 | Lost 3 |
| » W: Rick Mahler (3-4) L: Bob Forsch (2-2) | Fourth | 9½ out |
| Saturday, May 17 |
| » Lost to Braves (17-18), 2-0 | Atlanta-Fulton County Stadium (0-2) | 13-19 | Lost 4 |
| » W: Joe Johnson (5-3) L: Danny Cox (0-3) S: Bruce Sutter (3) | Fifth | 9½ out |
| Sunday, May 18 |
| » Lost to Braves (18-18), 5-2 | Atlanta-Fulton County Stadium (0-3) | 13-20 | Lost 5 |
| » W: Zane Smith (4-3) L: John Tudor (3-3) S: Paul Assenmacher (3) | Sixth | 10½ out |
| Tuesday, May 20 |
| » Lost to Reds (12-22), 5-3 | Busch Stadium II (8-10) | 13-21 | Lost 6 |
| » W: Bill Gullickson (3-3) L: Greg Bargar (0-1) S: John Franco (6) | Sixth | 11½ out |
| Wednesday, May 21 |
| » Defeated Reds (12-23), 8-3 | Busch Stadium II (9-10) | 14-21 | |
| » W: Bob Forsch (3-2) L: John Denny (2-5) S: Ken Dayley (2) | Fourth | 11½ out |
| Thursday, May 22 |
| » Lost to Reds (13-23), 6-4 | Busch Stadium II (9-11) | 14-22 | |
| » W: Mario Soto (3-6) L: Danny Cox (0-4) S: John Franco (7) | Fourth | 11½ out |
| Friday, May 23 |
| » Defeated Braves (21-19), 3-2 | Busch Stadium II (10-11) | 15-22 | |
| » W: John Tudor (4-3) L: Zane Smith (4-4) S: Todd Worrell (5) | Fourth | 10½ out |
| Saturday, May 24 |
| » Defeated Braves (21-20), 9-5 | Busch Stadium II (11-11) | 16-22 | Won 2 |
| » W: Ray Burris (2-0) L: David Palmer (3-3) S: Todd Worrell (6) | Third | 10½ out |
| Sunday, May 25 |
| » Lost to Braves (22-20), 6-2 | Busch Stadium II (11-12) | 16-23 | |
| » W: Rick Mahler (4-4) L: Tim Conroy (2-3) | Third | 11½ out |
| Monday, May 26 |
| » Lost to Astros (24-18), 4-1 | Busch Stadium II (11-13) | 16-24 | Lost 2 |
| » W: Jim Deshaies (1-1) L: Bob Forsch (3-3) S: Frank DiPino (2) | Fourth | 12 out |
| Tuesday, May 27 |
| » Lost to Astros (25-18), 5-4 | Busch Stadium II (11-14) | 16-25 | Lost 3 |
| » W: Dave Smith (1-2) L: Ken Dayley (0-3) | Fifth | 13 out |
| Wednesday, May 28 |
| » Lost to Astros (26-18), 4-3 | Busch Stadium II (11-15) | 16-26 | Lost 4 |
| » W: Charlie Kerfeld (5-1) L: Todd Worrell (3-3) | Sixth | 14 out |
| Former Cardinal Taylor Douthit dies in Fremont, CA at the age of 86. |
| Friday, May 30 |
| » Lost to Reds (18-25), 6-4 | Riverfront Stadium (0-1) | 16-27 | Lost 5 |
| » W: Joe Price (1-1) L: Ray Burris (2-1) S: John Franco (8) | Sixth | 15½ out |
| Saturday, May 31 |
| » Defeated Reds (18-26), 11-2 | Riverfront Stadium (1-1) | 17-27 | |
| » W: Bob Forsch (4-3) L: Tom Browning (2-5) | Sixth | 14½ out |
| Sunday, June 1 |
| » Defeated Reds (18-27), 2-1 | Riverfront Stadium (2-1) | 18-27 | Won 2 |
| » W: Danny Cox (1-4) L: Chris Welsh (0-1) S: Todd Worrell (7) | Sixth | 13½ out |
| Monday, June 2 |
| » Defeated Astros (28-20), 9-2 | Astrodome (1-0) | 19-27 | Won 3 |
| » W: John Tudor (5-3) L: Mike Madden (1-2) | Sixth | 13½ out |
| Tuesday, June 3 |
| » Defeated Astros (28-21), 3-1 | Astrodome (2-0) | 20-27 | Won 4 |
| » W: Greg Mathews (1-0) L: Jim Deshaies (1-2) S: Todd Worrell (8) | Fifth | 12½ out |
| » Major-league debuts: Greg Mathews (Cardinals) |
| Wednesday, June 4 |
| » Lost to Astros (29-21), 4-2 | Astrodome (2-1) | 20-28 | |
| » W: Mike Scott (5-4) L: Ray Burris (2-2) S: Dave Smith (13) | Sixth | 13½ out |
| Thursday, June 5 |
| » Defeated Cubs (21-29), 4-3 | Busch Stadium II (12-15) | 21-28 | |
| » W: Bob Forsch (5-3) L: Matt Keough (2-2) S: Todd Worrell (9) | Fourth | 13½ out |
| Friday, June 6 |
| » Lost to Cubs (22-29), 9-3 | Busch Stadium II (12-16) | 21-29 | |
| » W: Jay Baller (2-3) L: Danny Cox (1-5) | Sixth | 14 out |
| Saturday, June 7 |
| » Defeated Cubs (22-30), 3-2 | Busch Stadium II (13-16) | 22-29 | |
| » W: John Tudor (6-3) L: Rick Sutcliffe (4-7) | Fourth | 14 out |
| Sunday, June 8 |
| » Lost to Cubs (23-30), 14-2 | Busch Stadium II (13-17) | 22-30 | |
| » W: Steve Trout (3-3) L: Greg Mathews (1-1) | Fifth | 15 out |
| Monday, June 9 |
| » Lost to Expos (29-24), 5-4 | Busch Stadium II (13-18) | 22-31 | Lost 2 |
| » W: Tim Burke (4-1) L: Todd Worrell (3-4) S: Jeff Reardon (13) | Sixth | 15 out |
| Tuesday, June 10 |
| » Lost to Expos (30-24), 4-2 | Busch Stadium II (13-19) | 22-32 | Lost 3 |
| » W: Jay Tibbs (4-2) L: Bob Forsch (5-4) S: Jeff Reardon (14) | Sixth | 16 out |
| Wednesday, June 11 |
| » Lost to Expos (31-24), 4-3 | Busch Stadium II (13-20) | 22-33 | Lost 4 |
| » W: Jeff Reardon (6-3) L: Greg Bargar (0-2) S: Bert Roberge (1) | Sixth | 17 out |
| Friday, June 13 |
| » Defeated Cubs (23-34), 1-0 | Wrigley Field (1-2) | 23-33 | |
| » W: Greg Mathews (2-1) L: Rick Sutcliffe (4-8) S: Todd Worrell (10) | Sixth | 17½ out |
| » Lost to Cubs (24-34), 3-2 | Wrigley Field (1-3) | 23-34 | |
| » W: Lee Smith (3-4) L: Todd Worrell (3-5) | Sixth | 17½ out |
| Saturday, June 14 |
| » Defeated Cubs (24-35), 1-0 | Wrigley Field (2-3) | 24-34 | |
| » W: Ray Burris (3-2) L: Scott Sanderson (3-4) S: Todd Worrell (11) | Fifth | 17½ out |
| Sunday, June 15 |
| » Lost to Cubs (25-35), 4-3 | Wrigley Field (2-4) | 24-35 | |
| » W: Ray Fontenot (2-1) L: Todd Worrell (3-6) | Sixth | 19 out |
| » Major-league debuts: Dave Martinez (Cubs) |
| Monday, June 16 |
| » Game at Three Rivers Stadium interrupted in the 6th inning with the score of Cardinals 4, Pirates 1. Completed on June 18. |
| Tuesday, June 17 |
| » Defeated Pirates (24-35), 7-2 | Three Rivers Stadium (1-0) | 25-35 | |
| » W: Greg Mathews (3-1) L: Rick Reuschel (4-6) | Fifth | 18½ out |
| Wednesday, June 18 |
| » Defeated Pirates (24-36), 4-2 | Three Rivers Stadium (2-0) | 26-35 | Won 2 |
| » W: Danny Cox (2-5) L: Rick Rhoden (6-4) S: Todd Worrell (12) | Fifth | 18 out |
| » Lost to Pirates (25-36), 2-1 | Three Rivers Stadium (2-1) | 26-36 | |
| » W: Don Robinson (2-0) L: Todd Worrell (3-7) | Fifth | 18 out |
| Thursday, June 19 |
| » Lost to Phillies (30-32), 5-3 | Veteran's Stadium (0-1) | 26-37 | Lost 2 |
| » W: Kevin Gross (6-5) L: Ray Burris (3-3) S: Don Carman (1) | Sixth | 18½ out |
| Friday, June 20 |
| » Defeated Phillies (30-33), 9-2 | Veteran's Stadium (1-1) | 27-37 | |
| » W: Bob Forsch (6-4) L: Charles Hudson (4-5) | Fourth | 18½ out |
| Saturday, June 21 |
| » Defeated Phillies (30-34), 8-6 | Veteran's Stadium (2-1) | 28-37 | Won 2 |
| » W: Todd Worrell (4-7) L: Don Carman (3-1) S: Ken Dayley (3) | Fourth | 17½ out |
| Sunday, June 22 |
| » Defeated Phillies (30-35), 7-4 | Veteran's Stadium (3-1) | 29-37 | Won 3 |
| » W: Greg Mathews (4-1) L: Mike Maddux (0-3) S: Todd Worrell (13) | Fourth | 17½ out |
| Monday, June 23 |
| » Defeated Pirates (27-39), 2-1 | Busch Stadium II (14-20) | 30-37 | Won 4 |
| » W: Todd Worrell (5-7) L: Pat Clements (0-3) | Fourth | 16½ out |
| Tuesday, June 24 |
| » Defeated Pirates (27-40), 5-2 | Busch Stadium II (15-20) | 31-37 | Won 5 |
| » W: Ray Burris (4-3) L: Jim Winn (1-2) S: Ken Dayley (4) | Fourth | 15½ out |
| Wednesday, June 25 |
| » Defeated Pirates (27-41), 2-1 | Busch Stadium II (16-20) | 32-37 | Won 6 |
| » W: Ricky Horton (1-3) L: Pat Clements (0-4) | Fourth | 15½ out |
| Friday, June 27 |
| » Lost to Phillies (33-36), 2-1 | Busch Stadium II (16-21) | 32-38 | |
| » W: Kent Tekulve (2-1) L: Rick Ownbey (1-2) S: Tom Hume (1) | Fourth | 16 out |
| Saturday, June 28 |
| » Lost to Phillies (34-36), 7-4 | Busch Stadium II (16-22) | 32-39 | Lost 2 |
| » W: Steve Bedrosian (4-3) L: Pat Perry (1-2) S: Tom Hume (2) | Fourth | 17 out |
| » Major-league debuts: Bruce Ruffin (Phillies) |
| Sunday, June 29 |
| » Lost to Phillies (35-36), 8-7 | Busch Stadium II (16-23) | 32-40 | Lost 3 |
| » W: Steve Bedrosian (5-3) L: Todd Worrell (5-8) | Fourth | 18 out |
| Monday, June 30 |
| » Lost to Mets (50-21), 7-0 | Busch Stadium II (16-24) | 32-41 | Lost 4 |
| » W: Bob Ojeda (9-2) L: John Tudor (6-4) | Fourth | 19 out |
| Tuesday, July 1 |
| » Lost to Mets (51-21), 2-1 | Busch Stadium II (16-25) | 32-42 | Lost 5 |
| » W: Sid Fernandez (10-2) L: Danny Cox (2-6) S: Roger McDowell (7) | Fourth | 20 out |
| Wednesday, July 2 |
| » Lost to Mets (52-21), 4-3 | Busch Stadium II (16-26) | 32-43 | Lost 6 |
| » W: Doug Sisk (2-1) L: Bob Forsch (6-5) S: Jesse Orosco (12) | Fourth | 21 out |
| Former Cardinal Peanuts Lowrey dies in Inglewood, CA at the age of 69. |
| Thursday, July 3 |
| » Lost to Giants (43-36), 1-0 | Candlestick Park (1-2) | 32-44 | Lost 7 |
| » W: Mike Krukow (10-4) L: Rick Ownbey (1-3) | Fourth | 22 out |
| Friday, July 4 |
| » Lost to Giants (44-36), 6-1 | Candlestick Park (1-3) | 32-45 | Lost 8 |
| » W: Mike LaCoss (8-3) L: Ray Burris (4-4) | Fourth | 23 out |
| Saturday, July 5 |
| » Defeated Giants (44-37), 7-4 | Candlestick Park (2-3) | 33-45 | |
| » W: Todd Worrell (6-8) L: Juan Berenguer (1-1) S: Ken Dayley (5) | Fourth | 22 out |
| Sunday, July 6 |
| » Lost to Giants (45-37), 8-3 | Candlestick Park (2-4) | 33-46 | |
| » W: Scott Garrelts (7-7) L: Danny Cox (2-7) | Fourth | 23 out |
| Former Cardinal Eddie Yuhas dies in Winston-Salem, NC at the age of 62. |
| Monday, July 7 |
| » Lost to Dodgers (37-45), 1-0 | Dodger Stadium (1-3) | 33-47 | Lost 2 |
| » W: Alejandro Pena (1-1) L: Bob Forsch (6-6) S: Ken Howell (6) | Fifth | 23 out |
| Tuesday, July 8 |
| » Defeated Dodgers (37-46), 1-0 | Dodger Stadium (2-3) | 34-47 | |
| » W: Tim Conroy (3-3) L: Bob Welch (4-7) S: Ricky Horton (1) | Fourth | 22 out |
| Former Cardinal Skeeter Webb dies in Meridian, MS at the age of 77. |
| Wednesday, July 9 |
| » Lost to Dodgers (38-46), 8-2 | Dodger Stadium (2-4) | 34-48 | |
| » W: Fernando Valenzuela (11-6) L: Greg Mathews (4-2) | Sixth | 22 out |
| Thursday, July 10 |
| » Lost to Padres (44-41), 4-3 | San Diego/Jack Murphy Stadium (0-3) | 34-49 | Lost 2 |
| » W: Craig Lefferts (6-3) L: John Tudor (6-5) | Sixth | 23 out |
| Friday, July 11 |
| » Defeated Padres (44-42), 4-2 | San Diego/Jack Murphy Stadium (1-3) | 35-49 | |
| » W: Danny Cox (3-7) L: Andy Hawkins (6-6) S: Todd Worrell (14) | Sixth | 23 out |
| Saturday, July 12 |
| » Defeated Padres (44-43), 4-2 | San Diego/Jack Murphy Stadium (2-3) | 36-49 | Won 2 |
| » W: Bob Forsch (7-6) L: Ed Whitson (5-3) S: Todd Worrell (15) | Fifth | 23 out |
| Sunday, July 13 |
| » Lost to Padres (45-43), 13-6 | San Diego/Jack Murphy Stadium (2-4) | 36-50 | |
| » W: LaMarr Hoyt (5-4) L: Tim Conroy (3-4) S: Bob Stoddard (1) | Fifth | 24 out |
| Thursday, July 17 |
| » Defeated Dodgers (40-49), 12-2 | Busch Stadium II (17-26) | 37-50 | |
| » W: John Tudor (7-5) L: Orel Hershiser (8-7) | Fourth | 24 out |
| Friday, July 18 |
| » Lost to Dodgers (41-49), 4-3 | Busch Stadium II (17-27) | 37-51 | |
| » W: Fernando Valenzuela (12-6) L: Danny Cox (3-8) S: Tom Niedenfuer (5) | Fifth | 24 out |
| Saturday, July 19 |
| » Defeated Dodgers (41-50), 2-1 | Busch Stadium II (18-27) | 38-51 | |
| » W: Bob Forsch (8-6) L: Bob Welch (4-8) S: Todd Worrell (16) | Fifth | 23 out |
| Sunday, July 20 |
| » Lost to Dodgers (42-50), 7-2 | Busch Stadium II (18-28) | 38-52 | |
| » W: Rick Honeycutt (6-5) L: Tim Conroy (3-5) S: Ken Howell (7) | Sixth | 23 out |
| Monday, July 21 |
| » Defeated Giants (50-43), 8-3 | Busch Stadium II (19-28) | 39-52 | |
| » W: Greg Mathews (5-2) L: Steve Carlton (4-10) | Fifth | 23 out |
| Tuesday, July 22 |
| » Defeated Giants (50-44), 10-7 | Busch Stadium II (20-28) | 40-52 | Won 2 |
| » W: John Tudor (8-5) L: Vida Blue (7-5) S: Todd Worrell (17) | Fifth | 23 out |
| Wednesday, July 23 |
| » Defeated Giants (50-45), 4-3 | Busch Stadium II (21-28) | 41-52 | Won 3 |
| » W: Danny Cox (4-8) L: Mike LaCoss (9-5) S: Todd Worrell (18) | Fourth | 23 out |
| Friday, July 25 |
| » Defeated Padres (47-49), 3-2 | Busch Stadium II (22-28) | 42-52 | Won 4 |
| » W: Bob Forsch (9-6) L: Ed Whitson (5-4) S: Todd Worrell (19) | Fourth | 22½ out |
| Saturday, July 26 |
| » Defeated Padres (47-50), 4-2 | Busch Stadium II (23-28) | 43-52 | Won 5 |
| » W: Greg Mathews (6-2) L: LaMarr Hoyt (5-6) S: Ricky Horton (2) | Fourth | 21 out |
| Sunday, July 27 |
| » Defeated Padres (47-51), 3-2 | Busch Stadium II (24-28) | 44-52 | Won 6 |
| » W: John Tudor (9-5) L: Lance McCullers (5-5) S: Todd Worrell (20) | Fourth | 21 out |
| Monday, July 28 |
| » Defeated Phillies (48-49), 3-1 | Veteran's Stadium (4-1) | 45-52 | Won 7 |
| » W: Danny Cox (5-8) L: Bruce Ruffin (3-2) | Fourth | 21 out |
| Tuesday, July 29 |
| » Lost to Phillies (49-49), 12-7 | Veteran's Stadium (4-2) | 45-53 | |
| » W: Tom Hume (3-0) L: Tim Conroy (3-6) | Fourth | 21½ out |
| Wednesday, July 30 |
| » Defeated Phillies (49-50), 6-3 | Veteran's Stadium (5-2) | 46-53 | |
| » W: Bob Forsch (10-6) L: Charles Hudson (6-10) S: Todd Worrell (21) | Fourth | 20½ out |
| Friday, August 1 |
| » Lost to Pirates (41-57), 4-0 | Three Rivers Stadium (2-2) | 46-54 | |
| » W: Rick Rhoden (11-6) L: Greg Mathews (6-3) | Fourth | 21½ out |
| Saturday, August 2 |
| » Defeated Pirates (41-58), 7-3 | Three Rivers Stadium (3-2) | 47-54 | |
| » W: John Tudor (10-5) L: Larry McWilliams (2-7) | Fourth | 21½ out |
| Sunday, August 3 |
| » Lost to Pirates (42-58), 3-0 | Three Rivers Stadium (3-3) | 47-55 | |
| » W: Rick Reuschel (7-12) L: Danny Cox (5-9) | Fourth | 22½ out |
| Monday, August 4 |
| » Defeated Phillies (52-51), 3-2 | Busch Stadium II (25-28) | 48-55 | |
| » W: Todd Worrell (7-8) L: Dan Schatzeder (3-3) | Fourth | 21½ out |
| Tuesday, August 5 |
| » Defeated Phillies (52-52), 7-4 | Busch Stadium II (26-28) | 49-55 | Won 2 |
| » W: Bob Forsch (11-6) L: Mike Maddux (0-4) | Fourth | 20½ out |
| » Major-league debuts: John Morris (Cardinals) |
| Wednesday, August 6 |
| » Defeated Phillies (52-53), 2-1 | Busch Stadium II (27-28) | 50-55 | Won 3 |
| » W: Greg Mathews (7-3) L: Don Carman (5-3) S: Todd Worrell (22) | Fourth | 20½ out |
| Thursday, August 7 |
| » Defeated Phillies (52-54), 6-5 | Busch Stadium II (28-28) | 51-55 | Won 4 |
| » W: John Tudor (11-5) L: Kevin Gross (7-9) S: Todd Worrell (23) | Fourth | 21 out |
| Friday, August 8 |
| » Defeated Pirates (42-63), 3-1 | Busch Stadium II (29-28) | 52-55 | Won 5 |
| » W: Danny Cox (6-9) L: Rick Reuschel (7-13) S: Ricky Horton (3) | Third | 20 out |
| Saturday, August 9 |
| » Lost to Pirates (43-63), 8-5 | Busch Stadium II (29-29) | 52-56 | |
| » W: Bob Walk (5-6) L: Ray Burris (4-5) S: Don Robinson (6) | Fourth | 21 out |
| Sunday, August 10 |
| » Defeated Pirates (43-64), 5-4 | Busch Stadium II (30-29) | 53-56 | |
| » W: Bob Forsch (12-6) L: Mike Bielecki (6-8) S: Todd Worrell (24) | Third | 21 out |
| Monday, August 11 |
| » Defeated Expos (55-53), 5-4 | Stade Olympique (3-1) | 54-56 | Won 2 |
| » W: Greg Mathews (8-3) L: Floyd Youmans (11-8) S: Todd Worrell (25) | Third | 21 out |
| Tuesday, August 12 |
| » Lost to Expos (56-53), 10-3 | Stade Olympique (3-2) | 54-57 | |
| » W: Bob Sebra (2-2) L: John Tudor (11-6) | Third | 21 out |
| Wednesday, August 13 |
| » Defeated Expos (56-54), 6-2 | Stade Olympique (4-2) | 55-57 | |
| » W: Danny Cox (7-9) L: Bryn Smith (8-7) | Third | 20 out |
| Thursday, August 14 |
| » Lost to Mets (76-37), 4-3 | Shea Stadium (1-1) | 55-58 | |
| » W: Roger McDowell (12-6) L: Todd Worrell (7-9) | Fourth | 20 out |
| » Defeated Mets (76-38), 5-1 | Shea Stadium (2-1) | 56-58 | |
| » W: Ricky Horton (2-3) L: Rick Anderson (1-1) | Fourth | 20 out |
| Friday, August 15 |
| » Defeated Mets (76-39), 4-2 | Shea Stadium (3-1) | 57-58 | Won 2 |
| » W: Pat Perry (2-2) L: Jesse Orosco (4-5) S: Todd Worrell (26) | Third | 19 out |
| Saturday, August 16 |
| » Defeated Mets (76-40), 3-1 | Shea Stadium (4-1) | 58-58 | Won 3 |
| » W: Greg Mathews (9-3) L: Roger McDowell (12-7) S: Todd Worrell (27) | Third | 18 out |
| Sunday, August 17 |
| » Defeated Mets (76-41), 2-1 | Shea Stadium (5-1) | 59-58 | Won 4 |
| » W: John Tudor (12-6) L: Rick Aguilera (6-5) S: Pat Perry (2) | Third | 18 out |
| » Lost to Mets (77-41), 9-2 | Shea Stadium (5-2) | 59-59 | |
| » W: Randy Niemann (2-3) L: Danny Cox (7-10) S: Roger McDowell (12) | Third | 18 out |
| Tuesday, August 19 |
| » Lost to Reds (58-61), 6-1 | Riverfront Stadium (2-2) | 59-60 | Lost 2 |
| » W: Tom Browning (10-10) L: Tim Conroy (3-7) | Fourth | 19½ out |
| Wednesday, August 20 |
| » Lost to Reds (59-61), 3-1 | Riverfront Stadium (2-3) | 59-61 | Lost 3 |
| » W: Bill Gullickson (10-8) L: Bob Forsch (12-7) S: John Franco (21) | Fourth | 20½ out |
| Thursday, August 21 |
| » Lost to Reds (60-61), 9-4 | Riverfront Stadium (2-4) | 59-62 | Lost 4 |
| » W: Chris Welsh (5-4) L: Greg Mathews (9-4) S: Ron Robinson (10) | Fourth | 21 out |
| Friday, August 22 |
| » Defeated Astros (69-53), 6-5 | Busch Stadium II (31-29) | 60-62 | |
| » W: John Tudor (13-6) L: Nolan Ryan (8-8) S: Todd Worrell (28) | Fourth | 21 out |
| Saturday, August 23 |
| » Defeated Astros (69-54), 7-1 | Busch Stadium II (32-29) | 61-62 | Won 2 |
| » W: Danny Cox (8-10) L: Mike Scott (13-9) | Fourth | 21 out |
| Sunday, August 24 |
| » Lost to Astros (70-54), 5-1 | Busch Stadium II (32-30) | 61-63 | |
| » W: Jim Deshaies (9-3) L: Tim Conroy (3-8) S: Aurelio Lopez (5) | Fourth | 21 out |
| Monday, August 25 |
| » Lost to Braves (59-65), 4-2 | Busch Stadium II (32-31) | 61-64 | Lost 2 |
| » W: David Palmer (10-8) L: Bob Forsch (12-8) S: Gene Garber (20) | Fourth | 22 out |
| Tuesday, August 26 |
| » Defeated Braves (59-66), 7-1 | Busch Stadium II (33-31) | 62-64 | |
| » W: Greg Mathews (10-4) L: Jim Acker (5-7) | Fourth | 22 out |
| Wednesday, August 27 |
| » Defeated Braves (59-67), 2-1 | Busch Stadium II (34-31) | 63-64 | Won 2 |
| » W: Todd Worrell (8-9) L: Rick Mahler (11-14) | Third | 22 out |
| Friday, August 29 |
| » Lost to Reds (66-62), 2-0 | Busch Stadium II (34-32) | 63-65 | |
| » W: Bill Gullickson (12-8) L: Danny Cox (8-11) | Fourth | 23 out |
| Saturday, August 30 |
| » Defeated Reds (66-63), 5-2 | Busch Stadium II (35-32) | 64-65 | |
| » W: Tim Conroy (4-8) L: Chris Welsh (5-5) S: Todd Worrell (29) | Third | 23 out |
| Sunday, August 31 |
| » Defeated Reds (66-64), 9-3 | Busch Stadium II (36-32) | 65-65 | Won 2 |
| » W: Bob Forsch (13-8) L: Tom Browning (11-11) | Third | 22 out |
| » Major-league debuts: Bill Landrum (Reds) |
| Monday, September 1 |
| » Defeated Braves (61-69), 5-2 | Atlanta-Fulton County Stadium (1-3) | 66-65 | Won 3 |
| » W: Ray Soff (1-0) L: Jim Acker (5-8) S: Todd Worrell (30) | Third | 22 out |
| Tuesday, September 2 |
| » Lost to Braves (62-69), 4-2 | Atlanta-Fulton County Stadium (1-4) | 66-66 | |
| » W: Rick Mahler (12-14) L: John Tudor (13-7) S: Gene Garber (22) | Third | 22 out |
| Wednesday, September 3 |
| » Defeated Braves (62-70), 5-3 | Atlanta-Fulton County Stadium (2-4) | 67-66 | |
| » W: Danny Cox (9-11) L: Zane Smith (7-14) S: Todd Worrell (31) | Third | 22 out |
| » Major-league debuts: Jim Lindeman (Cardinals) |
| Friday, September 5 |
| » Defeated Astros (76-58), 8-5 | Astrodome (3-1) | 68-66 | Won 2 |
| » W: Ray Soff (2-0) L: Aurelio Lopez (3-2) | Third | 21½ out |
| Saturday, September 6 |
| » Lost to Astros (77-58), 7-6 | Astrodome (3-2) | 68-67 | |
| » W: Charlie Kerfeld (9-2) L: Todd Worrell (8-10) | Third | 22½ out |
| Sunday, September 7 |
| » Lost to Astros (78-58), 6-3 | Astrodome (3-3) | 68-68 | Lost 2 |
| » W: Jeff Calhoun (1-0) L: Greg Mathews (10-5) S: Dave Smith (29) | Third | 24 out |
| Monday, September 8 |
| » Lost to Pirates (56-80), 3-2 | Three Rivers Stadium (3-4) | 68-69 | Lost 3 |
| » W: Bob Patterson (1-2) L: Danny Cox (9-12) S: Hipolito Pena (1) | Fourth | 24 out |
| Tuesday, September 9 |
| » Defeated Pirates (56-81), 3-1 | Three Rivers Stadium (4-4) | 69-69 | |
| » W: Ricky Horton (3-3) L: Rick Reuschel (8-16) S: Todd Worrell (32) | Fourth | 23 out |
| Wednesday, September 10 |
| » Defeated Pirates (56-82), 4-3 | Three Rivers Stadium (5-4) | 70-69 | Won 2 |
| » W: Ray Soff (3-0) L: Barry Jones (2-3) S: Todd Worrell (33) | Third | 23 out |
| Friday, September 12 |
| » Lost to Expos (69-69), 4-3 | Busch Stadium II (36-33) | 70-70 | |
| » W: Andy McGaffigan (9-5) L: Joe Boever (0-1) S: Jeff Reardon (32) | Fourth | 23 out |
| Saturday, September 13 |
| » Lost to Expos (70-69), 5-1 | Busch Stadium II (36-34) | 70-71 | Lost 2 |
| » W: Dennis Martinez (3-5) L: Greg Mathews (10-6) S: Jeff Reardon (33) | Fourth | 23 out |
| Sunday, September 14 |
| » Defeated Expos (70-70), 10-2 | Busch Stadium II (37-34) | 71-71 | |
| » W: Danny Cox (10-12) L: Bob Sebra (4-4) | Fourth | 22 out |
| Monday, September 15 |
| » Defeated Mets (93-50), 1-0 | Busch Stadium II (38-34) | 72-71 | Won 2 |
| » W: Todd Worrell (9-10) L: Roger McDowell (13-9) | Third | 21 out |
| Tuesday, September 16 |
| » Lost to Mets (94-50), 4-2 | Busch Stadium II (38-35) | 72-72 | |
| » W: Rick Aguilera (8-6) L: Tim Conroy (4-9) S: Jesse Orosco (18) | Fourth | 22 out |
| Wednesday, September 17 |
| » Defeated Phillies (76-69), 8-5 | Veteran's Stadium (6-2) | 73-72 | |
| » W: Bob Forsch (14-8) L: Bruce Ruffin (8-4) S: Todd Worrell (34) | Third | 22 out |
| Thursday, September 18 |
| » Lost to Phillies (77-69), 4-3 | Veteran's Stadium (6-3) | 73-73 | |
| » W: Mike Maddux (3-6) L: Greg Mathews (10-7) S: Steve Bedrosian (26) | Third | 23 out |
| Friday, September 19 |
| » Lost to Expos (73-73), 3-2 | Stade Olympique (4-3) | 73-74 | Lost 2 |
| » W: Bob McClure (4-4) L: Pat Perry (2-3) | Fourth | 23 out |
| Saturday, September 20 |
| » Defeated Expos (73-74), 3-1 | Stade Olympique (5-3) | 74-74 | |
| » W: Ricky Horton (4-3) L: Sergio Valdez (0-3) | Third | 23 out |
| Sunday, September 21 |
| » Defeated Expos (73-75), 7-2 | Stade Olympique (6-3) | 75-74 | Won 2 |
| » W: Tim Conroy (5-9) L: Jay Tibbs (7-9) | Third | 22 out |
| Monday, September 22 |
| » Lost to Mets (98-52), 5-2 | Shea Stadium (5-3) | 75-75 | |
| » W: Dwight Gooden (16-6) L: Bob Forsch (14-9) | Third | 23 out |
| Tuesday, September 23 |
| » Lost to Mets (99-52), 9-1 | Shea Stadium (5-4) | 75-76 | Lost 2 |
| » W: Bob Ojeda (17-5) L: Greg Mathews (10-8) S: Jesse Orosco (19) | Fourth | 24 out |
| Wednesday, September 24 |
| » Defeated Phillies (80-72), 7-1 | Busch Stadium II (39-35) | 76-76 | |
| » W: Danny Cox (11-12) L: Kevin Gross (11-12) | Third | 23 out |
| Thursday, September 25 |
| » Defeated Phillies (80-73), 5-4 | Busch Stadium II (40-35) | 77-76 | Won 2 |
| » W: Ray Soff (4-0) L: Dan Schatzeder (4-5) S: Todd Worrell (35) | Third | 23 out |
| Friday, September 26 |
| » Lost to Cubs (66-88), 4-1 | Busch Stadium II (40-36) | 77-77 | |
| » W: Rick Sutcliffe (5-14) L: Tim Conroy (5-10) S: Lee Smith (30) | Third | 24 out |
| Saturday, September 27 |
| » Lost to Cubs (67-88), 5-3 | Busch Stadium II (40-37) | 77-78 | Lost 2 |
| » W: Ed Lynch (6-5) L: Ray Soff (4-1) | Third | 25 out |
| Sunday, September 28 |
| » Defeated Cubs (67-89), 4-1 | Busch Stadium II (41-37) | 78-78 | |
| » W: Greg Mathews (11-8) L: Steve Trout (5-7) S: Todd Worrell (36) | Third | 25 out |
| Tuesday, September 30 |
| » Defeated Pirates (62-95), 5-3 | Busch Stadium II (42-37) | 79-78 | Won 2 |
| » W: Danny Cox (12-12) L: Rick Rhoden (15-12) | Third | 24 out |
| Wednesday, October 1 |
| » Lost to Pirates (63-95), 4-3 | Busch Stadium II (42-38) | 79-79 | |
| » W: Larry McWilliams (3-11) L: Ray Soff (4-2) S: Don Robinson (14) | Third | 25 out |
| Thursday, October 2 |
| » Lost to Pirates (64-95), 5-1 | Busch Stadium II (42-39) | 79-80 | Lost 2 |
| » W: Bob Kipper (6-8) L: Tim Conroy (5-11) | Third | 26 out |
| Saturday, October 4 |
| » Lost to Cubs (69-90), 8-7 | Wrigley Field (2-5) | 79-81 | Lost 3 |
| » W: Ed Lynch (7-5) L: Bob Forsch (14-10) S: Lee Smith (31) | Third | 27½ out |
| Sunday, October 5 |
| » Lost to Cubs (70-90), 8-1 | Wrigley Field (2-6) | 79-82 | Lost 4 |
| » W: Guy Hoffman (6-2) L: Danny Cox (12-13) S: Drew Hall (1) | Third | 28½ out |
| Wednesday, October 8 |
| Former Cardinal Max Surkont dies in Largo, FL at the age of 65. |
Game information provided by Retrosheet (www.retrosheet.org) |