| Sunday, February 10 |
| Former Pirate John Mokan dies in Buffalo, NY at the age of 90. |
| Friday, March 8 |
| Former Pirate Al Todd dies in Elmira, NY at the age of 84. |
| Monday, April 8 |
| » Major-league debuts: Lou Thornton (Blue Jays) |
| Former Pirate Joe Sullivan dies in Sequim, WA at the age of 75. |
| Tuesday, April 9 |
| » Lost to Cubs (1-0), 2-1 | Wrigley Field (0-1) | 0-1 | |
| » W: Rick Sutcliffe (1-0) L: Rick Rhoden (0-1) S: Lee Smith (1) | Second | 1 out |
| » Major-league debuts: Shawon Dunston (Cubs) |
| Wednesday, April 10 |
| » Major-league debuts: Manny Lee (Blue Jays) |
| Thursday, April 11 |
| » Lost to Cubs (2-0), 4-1 | Wrigley Field (0-2) | 0-2 | Lost 2 |
| » W: Steve Trout (1-0) L: Jose DeLeon (0-1) | Third | 2 out |
| Friday, April 12 |
| » Defeated Cardinals (0-3), 6-4 | Three Rivers Stadium (1-0) | 1-2 | |
| » W: Don Robinson (1-0) L: Kurt Kepshire (0-1) S: John Candelaria (1) | Third | 2 out |
| Saturday, April 13 |
| » Defeated Cardinals (0-4), 4-3 | Three Rivers Stadium (2-0) | 2-2 | Won 2 |
| » W: John Candelaria (1-0) L: Bill Campbell (0-1) | Third | 2 out |
| Sunday, April 14 |
| » Lost to Cardinals (1-4), 10-4 | Three Rivers Stadium (2-1) | 2-3 | |
| » W: Joaquin Andujar (1-0) L: Rick Rhoden (0-2) | Third | 3 out |
| Monday, April 15 |
| » Defeated Mets (5-1), 4-1 | Three Rivers Stadium (3-1) | 3-3 | |
| » W: Mike Bielecki (1-0) L: Bill Latham (0-1) S: John Candelaria (2) | Second | 2 out |
| » Major-league debuts: Bill Latham (Mets) |
| Tuesday, April 16 |
| » Lost to Mets (6-1), 2-1 | Three Rivers Stadium (3-2) | 3-4 | |
| » W: Jesse Orosco (1-0) L: John Candelaria (1-1) | Second | 3 out |
| Wednesday, April 17 |
| » Lost to Mets (7-1), 10-6 | Three Rivers Stadium (3-3) | 3-5 | Lost 2 |
| » W: Doug Sisk (1-0) L: Larry McWilliams (0-1) | Third | 4 out |
| Friday, April 19 |
| » Lost to Cardinals (3-6), 5-4 | Busch Stadium II (0-1) | 3-6 | Lost 3 |
| » W: Joaquin Andujar (2-0) L: John Candelaria (1-2) S: Neil Allen (1) | Fourth | 5 out |
| Saturday, April 20 |
| » Lost to Cardinals (4-6), 4-3 | Busch Stadium II (0-2) | 3-7 | Lost 4 |
| » W: Danny Cox (1-0) L: Lee Tunnell (0-1) S: Neil Allen (2) | Fifth | 5 out |
| Sunday, April 21 |
| » Lost to Cardinals (5-6), 6-0 | Busch Stadium II (0-3) | 3-8 | Lost 5 |
| » W: Bob Forsch (2-0) L: Jose DeLeon (0-2) | Fourth | 5 out |
| Monday, April 22 |
| » Defeated Cubs (8-4), 5-3 | Three Rivers Stadium (4-3) | 4-8 | |
| » W: Larry McWilliams (1-1) L: Dick Ruthven (0-1) S: John Candelaria (3) | Fifth | 5 out |
| Tuesday, April 23 |
| » Lost to Cubs (9-4), 5-0 | Three Rivers Stadium (4-4) | 4-9 | |
| » W: Rick Sutcliffe (3-1) L: Mike Bielecki (1-1) | Fourth | 5 out |
| Wednesday, April 24 |
| » Lost to Cubs (10-4), 5-2 | Three Rivers Stadium (4-5) | 4-10 | Lost 2 |
| » W: Steve Trout (3-1) L: Rick Rhoden (0-3) S: Lee Smith (4) | Fifth | 6 out |
| Friday, April 26 |
| » Lost to Mets (10-5), 6-0 | Shea Stadium (0-1) | 4-11 | Lost 3 |
| » W: Ron Darling (1-0) L: Jose DeLeon (0-3) | Fifth | 7 out |
| Saturday, April 27 |
| » Defeated Mets (10-6), 3-2 | Shea Stadium (1-1) | 5-11 | |
| » W: Larry McWilliams (2-1) L: Jesse Orosco (1-1) S: John Candelaria (4) | Fifth | 6 out |
| Sunday, April 28 |
| » Lost to Mets (11-6), 5-4 | Shea Stadium (1-2) | 5-12 | |
| » W: Tom Gorman (2-1) L: Lee Tunnell (0-2) | Fifth | 6½ out |
| Tuesday, April 30 |
| » Defeated Padres (10-9), 6-2 | Three Rivers Stadium (5-5) | 6-12 | |
| » W: Rick Rhoden (1-3) L: La Marr Hoyt (2-2) S: Al Holland (2) | Fourth | 6 out |
| Wednesday, May 1 |
| » Lost to Padres (11-9), 6-4 | Three Rivers Stadium (5-6) | 6-13 | |
| » W: Eric Show (3-1) L: Jose DeLeon (0-4) S: Rich Gossage (6) | Fifth | 7 out |
| Friday, May 3 |
| » Defeated Dodgers (12-11), 16-2 | Three Rivers Stadium (6-6) | 7-13 | |
| » W: Larry McWilliams (3-1) L: Rick Honeycutt (1-2) | Fourth | 6 out |
| Saturday, May 4 |
| » Lost to Dodgers (13-11), 6-5 | Three Rivers Stadium (6-7) | 7-14 | |
| » W: Fernando Valenzuela (3-3) L: John Candelaria (1-3) | Fifth | 7 out |
| Sunday, May 5 |
| » Defeated Dodgers (13-12), 3-2 | Three Rivers Stadium (7-7) | 8-14 | |
| » W: Rick Rhoden (2-3) L: Tom Niedenfuer (1-1) S: John Candelaria (5) | Fifth | 6½ out |
| Monday, May 6 |
| » Lost to Giants (9-15), 7-5 | Three Rivers Stadium (7-8) | 8-15 | |
| » W: Bill Laskey (1-3) L: Jose DeLeon (0-5) S: Scott Garrelts (2) | Fifth | 6½ out |
| Former Pirate Kirby Higbe dies in Columbia, SC at the age of 71. |
| Tuesday, May 7 |
| » Lost to Giants (10-15), 5-3 | Three Rivers Stadium (7-9) | 8-16 | Lost 2 |
| » W: Jim Gott (2-0) L: Lee Tunnell (0-3) S: Scott Garrelts (3) | Fifth | 7½ out |
| Wednesday, May 8 |
| » Lost to Padres (14-11), 12-2 | San Diego/Jack Murphy Stadium (0-1) | 8-17 | Lost 3 |
| » W: Andy Hawkins (6-0) L: Larry McWilliams (3-2) | Fifth | 8½ out |
| Thursday, May 9 |
| » Lost to Padres (15-11), 1-0 | San Diego/Jack Murphy Stadium (0-2) | 8-18 | Lost 4 |
| » W: Mark Thurmond (1-2) L: Mike Bielecki (1-2) | Sixth | 9 out |
| Friday, May 10 |
| » Lost to Dodgers (16-14), 1-0 | Dodger Stadium (0-1) | 8-19 | Lost 5 |
| » W: Jerry Reuss (2-3) L: Rick Rhoden (2-4) S: Steve Howe (2) | Sixth | 10 out |
| Saturday, May 11 |
| » Defeated Dodgers (16-15), 5-2 | Dodger Stadium (1-1) | 9-19 | |
| » W: Al Holland (1-1) L: Tom Brennan (1-3) | Sixth | 10 out |
| Sunday, May 12 |
| » Lost to Dodgers (17-15), 2-0 | Dodger Stadium (1-2) | 9-20 | |
| » W: Bobby Castillo (1-0) L: Lee Tunnell (0-4) S: Tom Niedenfuer (2) | Sixth | 11 out |
| Tuesday, May 14 |
| » Lost to Giants (13-18), 3-1 | Candlestick Park (0-1) | 9-21 | Lost 2 |
| » W: Mike Krukow (3-2) L: Larry McWilliams (3-3) | Sixth | 11½ out |
| Wednesday, May 15 |
| » Defeated Giants (13-19), 3-2 | Candlestick Park (1-1) | 10-21 | |
| » W: Don Robinson (2-0) L: Scott Garrelts (2-2) | Sixth | 11½ out |
| Friday, May 17 |
| » Lost to Reds (18-16), 6-3 | Three Rivers Stadium (7-10) | 10-22 | |
| » W: John Stuper (5-2) L: Jose DeLeon (0-6) S: Ted Power (7) | Sixth | 12 out |
| Saturday, May 18 |
| » Lost to Reds (19-16), 8-0 | Three Rivers Stadium (7-11) | 10-23 | Lost 2 |
| » W: Tom Browning (4-2) L: Mike Bielecki (1-3) | Sixth | 12 out |
| Sunday, May 19 |
| » Lost to Reds (20-16), 7-1 | Three Rivers Stadium (7-12) | 10-24 | Lost 3 |
| » W: Mario Soto (6-3) L: Lee Tunnell (0-5) | Sixth | 13 out |
| Monday, May 20 |
| » Defeated Astros (20-17), 3-1 | Three Rivers Stadium (8-12) | 11-24 | |
| » W: Rick Rhoden (3-4) L: Joe Niekro (2-5) S: Al Holland (3) | Sixth | 12 out |
| Tuesday, May 21 |
| » Defeated Astros (20-18), 3-2 | Three Rivers Stadium (9-12) | 12-24 | Won 2 |
| » W: Rick Reuschel (1-0) L: Mike Scott (2-2) S: John Candelaria (6) | Sixth | 11½ out |
| Wednesday, May 22 |
| » Lost to Astros (21-18), 5-3 | Three Rivers Stadium (9-13) | 12-25 | |
| » W: Bill Dawley (1-2) L: Al Holland (1-2) S: Dave Smith (6) | Sixth | 11½ out |
| Friday, May 24 |
| » Defeated Braves (16-23), 4-2 | Atlanta-Fulton County Stadium (1-0) | 13-25 | |
| » W: Jim Winn (1-0) L: Steve Bedrosian (1-3) S: John Candelaria (7) | Sixth | 10½ out |
| Saturday, May 25 |
| » Defeated Braves (16-24), 8-2 | Atlanta-Fulton County Stadium (2-0) | 14-25 | Won 2 |
| » W: Rick Rhoden (4-4) L: Pascual Perez (0-5) | Fifth | 9½ out |
| Sunday, May 26 |
| » Lost to Braves (17-24), 5-4 | Atlanta-Fulton County Stadium (2-1) | 14-26 | |
| » W: Jeff Dedmon (2-0) L: Ray Krawczyk (0-1) | Fifth | 10½ out |
| Monday, May 27 |
| » Lost to Astros (23-20), 4-2 | Astrodome (0-1) | 14-27 | Lost 2 |
| » W: Bob Knepper (5-0) L: Jose DeLeon (0-7) S: Dave Smith (7) | Fifth | 11½ out |
| Tuesday, May 28 |
| » Defeated Astros (23-21), 4-3 | Astrodome (1-1) | 15-27 | |
| » W: Cecilio Guante (1-0) L: Julio Solano (1-1) | Sixth | 11 out |
| Wednesday, May 29 |
| » Lost to Astros (24-21), 8-3 | Astrodome (1-2) | 15-28 | |
| » W: Nolan Ryan (5-2) L: Ray Krawczyk (0-2) | Sixth | 12 out |
| Friday, May 31 |
| » Lost to Braves (19-26), 8-2 | Three Rivers Stadium (9-14) | 15-29 | Lost 2 |
| » W: Rick Camp (1-3) L: Rick Rhoden (4-5) | Sixth | 12½ out |
| Saturday, June 1 |
| » Defeated Braves (19-27), 6-3 | Three Rivers Stadium (10-14) | 16-29 | |
| » W: Rick Reuschel (2-0) L: Gene Garber (1-1) S: Rod Scurry (1) | Sixth | 12½ out |
| » Major-league debuts: Steve Shields (Braves) |
| Sunday, June 2 |
| » Defeated Braves (19-28), 5-0 | Three Rivers Stadium (11-14) | 17-29 | Won 2 |
| » W: Jose DeLeon (1-7) L: Steve Bedrosian (2-4) S: Al Holland (4) | Fifth | 12½ out |
| Tuesday, June 4 |
| » Lost to Reds (27-22), 9-3 | Riverfront Stadium (0-1) | 17-30 | |
| » W: Mario Soto (8-3) L: Cecilio Guante (1-1) | Sixth | 13 out |
| Wednesday, June 5 |
| » Lost to Reds (28-22), 11-9 | Riverfront Stadium (0-2) | 17-31 | Lost 2 |
| » W: Frank Pastore (1-0) L: Don Robinson (2-1) S: John Franco (1) | Sixth | 13 out |
| Thursday, June 6 |
| » Lost to Cubs (29-19), 3-2 | Wrigley Field (0-3) | 17-32 | Lost 3 |
| » W: Warren Brusstar (1-1) L: Al Holland (1-3) | Sixth | 13½ out |
| Friday, June 7 |
| » Lost to Cubs (30-19), 1-0 | Wrigley Field (0-4) | 17-33 | Lost 4 |
| » W: Rick Sutcliffe (6-4) L: Jose DeLeon (1-8) | Fifth | 13½ out |
| Saturday, June 8 |
| » Lost to Cubs (31-19), 7-3 | Wrigley Field (0-5) | 17-34 | Lost 5 |
| » W: Steve Trout (6-1) L: Larry McWilliams (3-4) | Sixth | 14½ out |
| Sunday, June 9 |
| » Lost to Cubs (32-19), 5-1 | Wrigley Field (0-6) | 17-35 | Lost 6 |
| » W: Dick Ruthven (3-4) L: Jim Winn (1-1) S: Warren Brusstar (1) | Sixth | 15½ out |
| Monday, June 10 |
| » Lost to Cardinals (30-25), 6-1 | Three Rivers Stadium (11-15) | 17-36 | Lost 7 |
| » W: Danny Cox (7-2) L: Rick Rhoden (4-6) | Sixth | 16½ out |
| Tuesday, June 11 |
| » Defeated Cardinals (30-26), 13-2 | Three Rivers Stadium (12-15) | 18-36 | |
| » W: Rick Reuschel (3-0) L: Neil Allen (1-4) | Sixth | 16½ out |
| Thursday, June 13 |
| » Lost to Cardinals (31-26), 2-1 | Three Rivers Stadium (12-16) | 18-37 | |
| » W: John Tudor (4-7) L: Larry McWilliams (3-5) S: Jeff Lahti (4) | Sixth | 16 out |
| Friday, June 14 |
| » Defeated Phillies (22-36), 3-2 | Three Rivers Stadium (13-16) | 19-37 | |
| » W: Jose DeLeon (2-8) L: Don Carman (0-1) S: Don Robinson (1) | Sixth | 15 out |
| Saturday, June 15 |
| » Lost to Phillies (23-36), 13-3 | Three Rivers Stadium (13-17) | 19-38 | |
| » W: John Denny (4-5) L: Rick Rhoden (4-7) | Sixth | 15 out |
| Sunday, June 16 |
| » Lost to Phillies (24-36), 3-2 | Three Rivers Stadium (13-18) | 19-39 | Lost 2 |
| » W: Charles Hudson (3-6) L: Rick Reuschel (3-1) S: Kent Tekulve (5) | Sixth | 16 out |
| Monday, June 17 |
| » Defeated Expos (37-26), 5-2 | Stade Olympique (1-0) | 20-39 | |
| » W: Jim Winn (2-1) L: David Palmer (5-6) S: Don Robinson (2) | Sixth | 15 out |
| Tuesday, June 18 |
| » Defeated Expos (37-27), 4-1 | Stade Olympique (2-0) | 21-39 | Won 2 |
| » W: Larry McWilliams (4-5) L: Bryn Smith (7-3) | Sixth | 14 out |
| Wednesday, June 19 |
| » Lost to Expos (38-27), 4-3 | Stade Olympique (2-1) | 21-40 | |
| » W: Tim Burke (3-0) L: Jose DeLeon (2-9) S: Jeff Reardon (20) | Fifth | 15 out |
| Thursday, June 20 |
| » Defeated Expos (38-28), 2-1 | Stade Olympique (3-1) | 22-40 | |
| » W: Rick Rhoden (5-7) L: Dan Schatzeder (2-3) S: Al Holland (5) | Fifth | 14 out |
| Friday, June 21 |
| » Lost to Phillies (26-38), 4-3 | Veteran's Stadium (0-1) | 22-41 | |
| » W: Larry Andersen (2-2) L: Jim Winn (2-2) | Fifth | 14½ out |
| Saturday, June 22 |
| » Lost to Phillies (27-38), 5-2 | Veteran's Stadium (0-2) | 22-42 | Lost 2 |
| » W: Don Carman (1-1) L: Don Robinson (2-2) | Sixth | 15½ out |
| Sunday, June 23 |
| » Lost to Phillies (28-38), 3-2 | Veteran's Stadium (0-3) | 22-43 | Lost 3 |
| » W: Don Carman (2-1) L: Jim Winn (2-3) | Sixth | 16½ out |
| Tuesday, June 25 |
| » Lost to Expos (41-29), 3-2 | Three Rivers Stadium (13-19) | 22-44 | Lost 4 |
| » W: Tim Burke (4-0) L: Al Holland (1-4) S: Jeff Reardon (21) | Sixth | 17 out |
| Wednesday, June 26 |
| » Defeated Expos (41-30), 11-2 | Three Rivers Stadium (14-19) | 23-44 | |
| » W: Rick Reuschel (4-1) L: Jack O'Connor (0-1) | Sixth | 16 out |
| Thursday, June 27 |
| » Lost to Expos (42-30), 4-2 | Three Rivers Stadium (14-20) | 23-45 | |
| » W: David Palmer (6-6) L: Larry McWilliams (4-6) S: Jeff Reardon (22) | Sixth | 17 out |
| Friday, June 28 |
| » Lost to Cubs (37-32), 5-0 | Three Rivers Stadium (14-21) | 23-46 | Lost 2 |
| » W: Steve Trout (7-3) L: Jose DeLeon (2-10) | Sixth | 18 out |
| Saturday, June 29 |
| » Defeated Cubs (37-33), 6-5 | Three Rivers Stadium (15-21) | 24-46 | |
| » W: Rick Reuschel (5-1) L: George Frazier (3-2) | Sixth | 17½ out |
| Sunday, June 30 |
| » Lost to Cubs (38-33), 9-2 | Three Rivers Stadium (15-22) | 24-47 | |
| » W: Scott Sanderson (4-3) L: Don Robinson (2-3) | Sixth | 18½ out |
| Monday, July 1 |
| » Defeated Mets (38-35), 1-0 | Shea Stadium (2-2) | 25-47 | |
| » W: Rick Reuschel (6-1) L: Sid Fernandez (2-5) S: John Candelaria (8) | Sixth | 17½ out |
| Tuesday, July 2 |
| » Lost to Mets (39-35), 5-4 | Shea Stadium (2-3) | 25-48 | |
| » W: Ron Darling (7-2) L: Larry McWilliams (4-7) S: Roger McDowell (5) | Sixth | 18½ out |
| Former Pirate Guy Bush dies in Shannon, MS at the age of 84. |
| Wednesday, July 3 |
| » Lost to Mets (40-35), 6-2 | Shea Stadium (2-4) | 25-49 | Lost 2 |
| » W: Ed Lynch (5-5) L: Jose DeLeon (2-11) | Sixth | 19 out |
| Thursday, July 4 |
| » Lost to Padres (46-31), 9-1 | Three Rivers Stadium (15-23) | 25-50 | Lost 3 |
| » W: Eric Show (7-5) L: Rick Rhoden (5-8) | Sixth | 20 out |
| Friday, July 5 |
| » Defeated Padres (46-32), 5-4 | Three Rivers Stadium (16-23) | 26-50 | |
| » W: Rick Reuschel (7-1) L: Craig Lefferts (4-3) | Sixth | 19 out |
| Saturday, July 6 |
| » Defeated Padres (46-33), 8-7 | Three Rivers Stadium (17-23) | 27-50 | Won 2 |
| » W: John Candelaria (2-3) L: Craig Lefferts (4-4) | Sixth | 18 out |
| Sunday, July 7 |
| » Lost to Padres (47-33), 3-0 | Three Rivers Stadium (17-24) | 27-51 | |
| » W: La Marr Hoyt (11-4) L: Rick Reuschel (7-2) | Sixth | 19 out |
| Monday, July 8 |
| » Lost to Dodgers (43-36), 4-3 | Three Rivers Stadium (17-25) | 27-52 | Lost 2 |
| » W: Fernando Valenzuela (9-8) L: Jose DeLeon (2-12) | Sixth | 20 out |
| Tuesday, July 9 |
| » Lost to Dodgers (44-36), 8-3 | Three Rivers Stadium (17-26) | 27-53 | Lost 3 |
| » W: Rick Honeycutt (6-7) L: Rick Rhoden (5-9) S: Tom Niedenfuer (7) | Sixth | 21 out |
| Wednesday, July 10 |
| » Lost to Dodgers (45-36), 5-4 | Three Rivers Stadium (17-27) | 27-54 | Lost 4 |
| » W: Jerry Reuss (7-6) L: Lee Tunnell (0-6) S: Ken Howell (8) | Sixth | 22 out |
| Thursday, July 11 |
| » Defeated Giants (31-54), 6-4 | Three Rivers Stadium (18-27) | 28-54 | |
| » W: Cecilio Guante (2-1) L: Mike Krukow (5-7) | Sixth | 22 out |
| Friday, July 12 |
| » Defeated Giants (31-55), 3-1 | Three Rivers Stadium (19-27) | 29-54 | Won 2 |
| » W: Rick Reuschel (8-2) L: Jim Gott (4-6) S: John Candelaria (9) | Sixth | 21 out |
| Saturday, July 13 |
| » Lost to Giants (32-55), 4-1 | Three Rivers Stadium (19-28) | 29-55 | |
| » W: Dave LaPoint (4-8) L: Jose DeLeon (2-13) | Sixth | 22 out |
| Sunday, July 14 |
| » Lost to Giants (33-55), 7-3 | Three Rivers Stadium (19-29) | 29-56 | Lost 2 |
| » W: Bill Laskey (2-11) L: Rick Rhoden (5-10) S: Mark Davis (6) | Sixth | 23 out |
| Thursday, July 18 |
| » Lost to Padres (50-39), 3-2 | San Diego/Jack Murphy Stadium (0-3) | 29-57 | Lost 3 |
| » W: Craig Lefferts (5-4) L: John Candelaria (2-4) S: Rich Gossage (19) | Sixth | 23 out |
| Friday, July 19 |
| » Lost to Padres (51-39), 6-0 | San Diego/Jack Murphy Stadium (0-4) | 29-58 | Lost 4 |
| » W: Andy Hawkins (12-2) L: Jose DeLeon (2-14) | Sixth | 23 out |
| Saturday, July 20 |
| » Lost to Padres (52-39), 4-2 | San Diego/Jack Murphy Stadium (0-5) | 29-59 | Lost 5 |
| » W: La Marr Hoyt (13-4) L: Rick Rhoden (5-11) S: Rich Gossage (20) | Sixth | 23 out |
| Sunday, July 21 |
| » Defeated Padres (52-40), 5-2 | San Diego/Jack Murphy Stadium (1-5) | 30-59 | |
| » W: Lee Tunnell (1-6) L: Eric Show (7-7) | Sixth | 23 out |
| Monday, July 22 |
| » Defeated Dodgers (51-39), 6-3 | Dodger Stadium (2-2) | 31-59 | Won 2 |
| » W: Larry McWilliams (5-7) L: Rick Honeycutt (6-9) S: Cecilio Guante (1) | Sixth | 23 out |
| Tuesday, July 23 |
| » Lost to Dodgers (52-39), 6-0 | Dodger Stadium (2-3) | 31-60 | |
| » W: Orel Hershiser (10-3) L: Rick Reuschel (8-3) | Sixth | 24 out |
| Wednesday, July 24 |
| » Lost to Dodgers (53-39), 9-1 | Dodger Stadium (2-4) | 31-61 | Lost 2 |
| » W: Bob Welch (5-1) L: Don Robinson (2-4) | Sixth | 25 out |
| Thursday, July 25 |
| » Lost to Giants (36-60), 4-3 | Candlestick Park (1-2) | 31-62 | Lost 3 |
| » W: Greg Minton (2-1) L: Cecilio Guante (2-2) | Sixth | 26 out |
| Friday, July 26 |
| » Lost to Giants (37-60), 3-1 | Candlestick Park (1-3) | 31-63 | Lost 4 |
| » W: Bill Laskey (4-11) L: Lee Tunnell (1-7) S: Scott Garrelts (7) | Sixth | 27 out |
| Saturday, July 27 |
| » Lost to Giants (38-60), 8-3 | Candlestick Park (1-4) | 31-64 | Lost 5 |
| » W: Dave LaPoint (5-9) L: Don Robinson (2-5) S: Greg Minton (4) | Sixth | 27 out |
| Sunday, July 28 |
| » Lost to Giants (39-60), 3-2 | Candlestick Park (1-5) | 31-65 | Lost 6 |
| » W: Scott Garrelts (5-3) L: Cecilio Guante (2-3) | Sixth | 28 out |
| Tuesday, July 30 |
| » Lost to Phillies (45-53), 2-0 | Three Rivers Stadium (19-30) | 31-66 | Lost 7 |
| » W: Kevin Gross (10-8) L: Rick Rhoden (5-12) S: Kent Tekulve (12) | Sixth | 29 out |
| Wednesday, July 31 |
| » Defeated Phillies (45-54), 4-3 | Three Rivers Stadium (20-30) | 32-66 | |
| » W: Cecilio Guante (3-3) L: Kent Tekulve (4-7) | Sixth | 28 out |
| Thursday, August 1 |
| » Lost to Phillies (46-54), 3-0 | Three Rivers Stadium (20-31) | 32-67 | |
| » W: John Denny (6-8) L: Don Robinson (2-6) | Sixth | 28 out |
| Friday, August 2 |
| » Lost to Expos (57-46), 3-2 | Three Rivers Stadium (20-32) | 32-68 | Lost 2 |
| » W: Joe Hesketh (9-4) L: Rick Reuschel (8-4) S: Jeff Reardon (26) | Sixth | 29 out |
| Saturday, August 3 |
| » Lost to Expos (58-46), 6-5 | Three Rivers Stadium (20-33) | 32-69 | Lost 3 |
| » W: Bert Roberge (2-1) L: Larry McWilliams (5-8) S: Jeff Reardon (27) | Sixth | 29 out |
| Sunday, August 4 |
| » Defeated Expos (58-47), 4-3 | Three Rivers Stadium (21-33) | 33-69 | |
| » W: Rick Rhoden (6-12) L: Bill Gullickson (10-8) S: Cecilio Guante (2) | Sixth | 28 out |
| Monday, August 5 |
| » Lost to Expos (59-47), 5-2 | Three Rivers Stadium (21-34) | 33-70 | |
| » W: Tim Burke (6-0) L: Jim Winn (2-4) S: Jeff Reardon (28) | Sixth | 28½ out |
| Thursday, August 8 |
| » Lost to Phillies (50-55), 7-3 | Veteran's Stadium (0-4) | 33-71 | Lost 2 |
| » W: John Denny (7-8) L: Don Robinson (2-7) S: Don Carman (4) | Sixth | 29½ out |
| Friday, August 9 |
| » Lost to Expos (60-48), 7-2 | Stade Olympique (3-2) | 33-72 | Lost 3 |
| » W: Bryn Smith (13-4) L: Rick Reuschel (8-5) S: Jeff Reardon (29) | Sixth | 30½ out |
| Saturday, August 10 |
| » Lost to Expos (61-48), 7-5 | Stade Olympique (3-3) | 33-73 | Lost 4 |
| » W: Randy St.claire (4-2) L: Rick Rhoden (6-13) S: Bert Roberge (2) | Fifth | 31½ out |
| Sunday, August 11 |
| » Lost to Expos (62-48), 6-5 | Stade Olympique (3-4) | 33-74 | Lost 5 |
| » W: Tim Burke (7-0) L: Cecilio Guante (3-4) | Sixth | 32½ out |
| Monday, August 12 |
| » Lost to Cardinals (66-43), 8-1 | Busch Stadium II (0-4) | 33-75 | Lost 6 |
| » W: John Tudor (15-8) L: Jim Winn (2-5) | Sixth | 33½ out |
| Tuesday, August 13 |
| » Lost to Cardinals (67-43), 6-5 | Busch Stadium II (0-5) | 33-76 | Lost 7 |
| » W: Joaquin Andujar (19-6) L: Don Robinson (2-8) S: Ken Dayley (8) | Sixth | 34½ out |
| Thursday, August 15 |
| » Lost to Cardinals (68-43), 3-1 | Busch Stadium II (0-6) | 33-77 | Lost 8 |
| » W: Kurt Kepshire (9-6) L: Rick Reuschel (8-6) S: Ken Dayley (9) | Fifth | 35½ out |
| » Lost to Cardinals (69-43), 4-3 | Busch Stadium II (0-7) | 33-78 | Lost 9 |
| » W: Bill Campbell (3-2) L: Cecilio Guante (3-5) | Fifth | 35½ out |
| Friday, August 16 |
| » Defeated Mets (69-44), 7-1 | Three Rivers Stadium (22-34) | 34-78 | |
| » W: Rick Rhoden (7-13) L: Ed Lynch (10-6) | Sixth | 35½ out |
| Saturday, August 17 |
| » Lost to Mets (70-44), 4-3 | Three Rivers Stadium (22-35) | 34-79 | |
| » W: Sid Fernandez (5-6) L: Lee Tunnell (1-8) S: Roger McDowell (10) | Fifth | 35½ out |
| Sunday, August 18 |
| » Defeated Mets (70-45), 5-0 | Three Rivers Stadium (23-35) | 35-79 | |
| » W: Don Robinson (3-8) L: Rick Aguilera (6-4) S: Pat Clements (2) | Fifth | 34½ out |
| Tuesday, August 20 |
| » Defeated Reds (61-55), 3-2 | Three Rivers Stadium (24-35) | 36-79 | Won 2 |
| » W: Rick Reuschel (9-6) L: Mario Soto (10-14) | Sixth | 35 out |
| Wednesday, August 21 |
| » Lost to Reds (62-55), 8-5 | Three Rivers Stadium (24-36) | 36-80 | |
| » W: Tom Browning (12-9) L: Bob Walk (0-1) S: John Franco (6) | Sixth | 35 out |
| Thursday, August 22 |
| » Defeated Reds (62-56), 5-1 | Three Rivers Stadium (25-36) | 37-80 | |
| » W: Rick Rhoden (8-13) L: Jay Tibbs (6-14) S: Rod Scurry (2) | Sixth | 35 out |
| Friday, August 23 |
| » Lost to Astros (56-64), 2-0 | Three Rivers Stadium (25-37) | 37-81 | |
| » W: Bill Dawley (2-2) L: Pat Clements (5-1) S: Frank DiPino (6) | Sixth | 35½ out |
| Sunday, August 25 |
| » Defeated Astros (56-65), 9-3 | Three Rivers Stadium (26-37) | 38-81 | |
| » W: Rick Reuschel (10-6) L: Mike Scott (13-7) | Sixth | 35½ out |
| » Defeated Astros (56-66), 10-9 | Three Rivers Stadium (27-37) | 39-81 | Won 2 |
| » W: Don Robinson (4-8) L: Jeff Calhoun (1-3) | Sixth | 35½ out |
| Monday, August 26 |
| » Lost to Braves (51-71), 2-1 | Atlanta-Fulton County Stadium (2-2) | 39-82 | |
| » W: Gene Garber (4-4) L: Don Robinson (4-9) | Sixth | 36½ out |
| Tuesday, August 27 |
| » Lost to Braves (52-71), 7-6 | Atlanta-Fulton County Stadium (2-3) | 39-83 | Lost 2 |
| » W: Gene Garber (5-4) L: Don Robinson (4-10) | Sixth | 37½ out |
| Former Pirate Johnny Lindell dies in Newport Beach, CA at the age of 69. |
| Wednesday, August 28 |
| » Lost to Braves (53-71), 6-1 | Atlanta-Fulton County Stadium (2-4) | 39-84 | Lost 3 |
| » W: Len Barker (2-6) L: Lee Tunnell (1-9) S: Craig McMurtry (1) | Sixth | 37½ out |
| Thursday, August 29 |
| » Lost to Reds (66-59), 6-0 | Riverfront Stadium (0-3) | 39-85 | Lost 4 |
| » W: Tom Browning (14-9) L: Jose DeLeon (2-15) | Sixth | 38 out |
| Friday, August 30 |
| » Lost to Reds (67-59), 1-0 | Riverfront Stadium (0-4) | 39-86 | Lost 5 |
| » W: Jay Tibbs (7-15) L: Rick Reuschel (10-7) | Sixth | 38 out |
| Saturday, August 31 |
| » Defeated Reds (67-60), 6-0 | Riverfront Stadium (1-4) | 40-86 | |
| » W: Bob Walk (1-1) L: Andy McGaffigan (1-2) | Sixth | 37 out |
| Sunday, September 1 |
| » Lost to Reds (68-60), 3-2 | Riverfront Stadium (1-5) | 40-87 | |
| » W: Mario Soto (11-15) L: Rod Scurry (0-1) S: John Franco (8) | Sixth | 38 out |
| Monday, September 2 |
| » Defeated Braves (55-74), 5-4 | Three Rivers Stadium (28-37) | 41-87 | |
| » W: Lee Tunnell (2-9) L: Rick Mahler (17-13) S: Cecilio Guante (3) | Fifth | 37 out |
| Tuesday, September 3 |
| » Lost to Braves (56-74), 2-0 | Three Rivers Stadium (28-38) | 41-88 | |
| » W: Joe Johnson (3-0) L: Jose DeLeon (2-16) S: Bruce Sutter (21) | Sixth | 38 out |
| » Major-league debuts: Andres Thomas (Braves) |
| Wednesday, September 4 |
| » Defeated Braves (56-75), 2-0 | Three Rivers Stadium (29-38) | 42-88 | |
| » W: Rick Reuschel (11-7) L: Pascual Perez (1-9) | Sixth | 38 out |
| Thursday, September 5 |
| » Lost to Astros (64-68), 4-3 | Astrodome (1-3) | 42-89 | |
| » W: Bob Knepper (12-10) L: Bob Walk (1-2) S: Dave Smith (21) | Sixth | 39 out |
| Friday, September 6 |
| » Lost to Astros (65-68), 4-3 | Astrodome (1-4) | 42-90 | Lost 2 |
| » W: Bill Dawley (4-2) L: Don Robinson (4-11) | Sixth | 40 out |
| Saturday, September 7 |
| » Defeated Astros (65-69), 7-1 | Astrodome (2-4) | 43-90 | |
| » W: Lee Tunnell (3-9) L: Charlie Kerfeld (1-2) | Sixth | 39 out |
| Tuesday, September 10 |
| » Defeated Cubs (65-71), 2-1 | Three Rivers Stadium (30-38) | 44-90 | Won 2 |
| » W: Rick Reuschel (12-7) L: Steve Engel (1-4) | Sixth | 38 out |
| Wednesday, September 11 |
| » Lost to Cubs (66-71), 3-1 | Three Rivers Stadium (30-39) | 44-91 | |
| » W: Ron Meridith (3-2) L: Jose DeLeon (2-17) S: Jay Baller (1) | Fifth | 38 out |
| Thursday, September 12 |
| » Defeated Cubs (66-72), 10-2 | Three Rivers Stadium (31-39) | 45-91 | |
| » W: Rick Rhoden (9-13) L: Dennis Eckersley (8-6) S: Don Robinson (3) | Sixth | 38 out |
| Friday, September 13 |
| » Lost to Phillies (69-69), 6-3 | Three Rivers Stadium (31-40) | 45-92 | |
| » W: John Denny (11-11) L: Bob Walk (1-3) S: Kent Tekulve (14) | Sixth | 38½ out |
| Saturday, September 14 |
| » Defeated Phillies (69-70), 6-3 | Three Rivers Stadium (32-40) | 46-92 | |
| » W: Lee Tunnell (4-9) L: Steve Carlton (1-8) S: Cecilio Guante (4) | Sixth | 38 out |
| Sunday, September 15 |
| » Defeated Phillies (69-71), 5-4 | Three Rivers Stadium (33-40) | 47-92 | Won 2 |
| » W: Rick Reuschel (13-7) L: Dave Shipanoff (1-2) | Sixth | 38 out |
| Monday, September 16 |
| » Lost to Cardinals (87-55), 8-4 | Three Rivers Stadium (33-41) | 47-93 | |
| » W: John Tudor (19-8) L: Jose DeLeon (2-18) S: Todd Worrell (2) | Sixth | 40 out |
| » Lost to Cardinals (88-55), 3-1 | Three Rivers Stadium (33-42) | 47-94 | Lost 2 |
| » W: Pat Perry (1-0) L: Pat Clements (5-2) | Sixth | 40 out |
| Tuesday, September 17 |
| » Lost to Cardinals (89-55), 10-4 | Three Rivers Stadium (33-43) | 47-95 | Lost 3 |
| » W: Joaquin Andujar (21-9) L: Bob Kipper (0-2) | Sixth | 41 out |
| Wednesday, September 18 |
| » Defeated Expos (77-68), 10-6 | Stade Olympique (4-4) | 48-95 | |
| » W: Don Robinson (5-11) L: Bert Roberge (3-2) | Sixth | 41 out |
| Thursday, September 19 |
| » Defeated Expos (77-69), 8-6 | Stade Olympique (5-4) | 49-95 | Won 2 |
| » W: Jim Winn (3-5) L: Tim Burke (9-4) | Sixth | 40 out |
| Friday, September 20 |
| » Defeated Mets (89-58), 7-5 | Shea Stadium (3-4) | 50-95 | Won 3 |
| » W: Cecilio Guante (4-5) L: Bill Latham (1-2) S: Jose DeLeon (1) | Sixth | 40 out |
| Saturday, September 21 |
| » Lost to Mets (90-58), 12-1 | Shea Stadium (3-5) | 50-96 | |
| » W: Dwight Gooden (22-4) L: Rick Rhoden (9-14) | Sixth | 41 out |
| Sunday, September 22 |
| » Defeated Mets (90-59), 5-3 | Shea Stadium (4-5) | 51-96 | |
| » W: Bob Kipper (1-2) L: Terry Leach (3-4) S: Pat Clements (3) | Sixth | 41 out |
| Monday, September 23 |
| » Lost to Cardinals (94-56), 5-4 | Busch Stadium II (0-8) | 51-97 | |
| » W: Jeff Lahti (5-2) L: Cecilio Guante (4-6) S: Todd Worrell (4) | Sixth | 42 out |
| Tuesday, September 24 |
| » Lost to Cardinals (95-56), 5-4 | Busch Stadium II (0-9) | 51-98 | Lost 2 |
| » W: Ricky Horton (3-2) L: Lee Tunnell (4-10) S: Ken Dayley (11) | Sixth | 43 out |
| Wednesday, September 25 |
| » Defeated Expos (79-73), 8-2 | Three Rivers Stadium (34-43) | 52-98 | |
| » W: Rick Reuschel (14-7) L: Bill Laskey (5-15) | Sixth | 43 out |
| Friday, September 27 |
| » Defeated Mets (93-61), 8-7 | Three Rivers Stadium (35-43) | 53-98 | Won 2 |
| » W: Larry McWilliams (6-8) L: Wes Gardner (0-2) S: Jose DeLeon (2) | Sixth | 43 out |
| Saturday, September 28 |
| » Lost to Mets (94-61), 3-1 | Three Rivers Stadium (35-44) | 53-99 | |
| » W: Rick Aguilera (10-6) L: Bob Kipper (1-3) S: Jesse Orosco (17) | Sixth | 43½ out |
| Sunday, September 29 |
| » Lost to Mets (95-61), 9-7 | Three Rivers Stadium (35-45) | 53-100 | Lost 2 |
| » W: Jesse Orosco (7-6) L: Larry McWilliams (6-9) | Sixth | 43½ out |
| Tuesday, October 1 |
| » Lost to Cubs (75-81), 4-3 | Wrigley Field (0-7) | 53-101 | Lost 3 |
| » W: Reggie Patterson (2-0) L: Rick Reuschel (14-8) S: Lee Smith (33) | Sixth | 43½ out |
| Wednesday, October 2 |
| » Defeated Cubs (75-82), 9-4 | Wrigley Field (1-7) | 54-101 | |
| » W: Rick Rhoden (10-14) L: Rick Sutcliffe (8-8) S: Cecilio Guante (5) | Sixth | 42½ out |
| Thursday, October 3 |
| » Lost to Cubs (76-82), 13-5 | Wrigley Field (1-8) | 54-102 | |
| » W: Jon Perlman (1-0) L: Jim Winn (3-6) S: Steve Engel (1) | Sixth | 43½ out |
| Friday, October 4 |
| » Defeated Phillies (73-85), 7-2 | Veteran's Stadium (1-4) | 55-102 | |
| » W: Bob Walk (2-3) L: John Denny (11-14) S: Jose DeLeon (3) | Sixth | 44 out |
| » Lost to Phillies (74-85), 8-5 | Veteran's Stadium (1-5) | 55-103 | |
| » W: Don Carman (9-4) L: Jose DeLeon (2-19) | Sixth | 44 out |
| Saturday, October 5 |
| » Defeated Phillies (74-86), 4-2 | Veteran's Stadium (2-5) | 56-103 | |
| » W: Larry McWilliams (7-9) L: Freddie Toliver (0-4) S: Rick Reuschel (1) | Sixth | 43½ out |
| » Defeated Phillies (74-87), 5-0 | Veteran's Stadium (3-5) | 57-103 | Won 2 |
| » W: Mike Bielecki (2-3) L: Rocky Childress (0-1) | Sixth | 43½ out |
| Sunday, October 6 |
| » Lost to Phillies (75-87), 5-0 | Veteran's Stadium (3-6) | 57-104 | |
| » W: Kevin Gross (15-13) L: Rick Rhoden (10-15) | Sixth | 43½ out |
| Friday, December 6 |
| Former Pirate Burleigh Grimes dies in Clear Lake, WI at the age of 93. |
Game information provided by Retrosheet (www.retrosheet.org) |