| Wednesday, January 16 |
| Former Giant Ken Chase dies in Oneonta, NY at the age of 72. |
| Tuesday, February 12 |
| Former Giant Van Lingle Mungo dies in Pageland, SC at the age of 74. |
| Tuesday, February 26 |
| Former Giant George Uhle dies in Lakewood, OH at the age of 87. |
| Sunday, March 10 |
| Former Giant Bob Nieman dies in Corona, CA at the age of 59. |
| Monday, March 25 |
| Former Giant Curt Barclay dies in Missoula, MT at the age of 54. |
| Monday, April 8 |
| » Major-league debuts: Lou Thornton (Blue Jays) |
| Tuesday, April 9 |
| » Defeated Padres (0-1), 4-3 | Candlestick Park (1-0) | 1-0 | |
| » W: Vida Blue (1-0) L: Luis DeLeon (0-1) | First | -- |
| Wednesday, April 10 |
| » Lost to Padres (1-1), 3-0 | Candlestick Park (1-1) | 1-1 | |
| » W: Eric Show (1-0) L: Dave LaPoint (0-1) | Second | ½ out |
| Friday, April 12 |
| » Defeated Dodgers (2-2), 4-1 | Dodger Stadium (1-0) | 2-1 | |
| » W: Mike Krukow (1-0) L: Rick Honeycutt (0-1) | First | -- |
| Saturday, April 13 |
| » Lost to Dodgers (3-2), 1-0 | Dodger Stadium (1-1) | 2-2 | |
| » W: Fernando Valenzuela (1-1) L: Mark Davis (0-1) | Third | 1 out |
| Sunday, April 14 |
| » Defeated Dodgers (3-3), 8-4 | Dodger Stadium (2-1) | 3-2 | |
| » W: Jim Gott (1-0) L: Jerry Reuss (1-1) S: Scott Garrelts (1) | Second | 1 out |
| Monday, April 15 |
| » Lost to Padres (3-3), 8-3 | San Diego/Jack Murphy Stadium (0-1) | 3-3 | |
| » W: Eric Show (2-0) L: Atlee Hammaker (0-1) | Third | 1 out |
| Tuesday, April 16 |
| » Lost to Padres (4-3), 2-1 | San Diego/Jack Murphy Stadium (0-2) | 3-4 | Lost 2 |
| » W: Andy Hawkins (2-0) L: Dave LaPoint (0-2) S: Rich Gossage (1) | Third | 1 out |
| Thursday, April 18 |
| » Lost to Reds (5-4), 4-3 | Riverfront Stadium (0-1) | 3-5 | Lost 3 |
| » W: Carl Willis (1-0) L: Greg Minton (0-1) | Fifth | 2 out |
| Friday, April 19 |
| » Lost to Reds (6-4), 4-2 | Riverfront Stadium (0-2) | 3-6 | Lost 4 |
| » W: John Stuper (2-0) L: Bill Laskey (0-1) S: Ted Power (2) | Fifth | 2½ out |
| Saturday, April 20 |
| » Lost to Reds (7-4), 2-1 | Riverfront Stadium (0-3) | 3-7 | Lost 5 |
| » W: Mario Soto (3-1) L: Frank Williams (0-1) | Sixth | 3½ out |
| Sunday, April 21 |
| » Lost to Reds (8-4), 1-0 | Riverfront Stadium (0-4) | 3-8 | Lost 6 |
| » W: Tom Browning (2-0) L: Atlee Hammaker (0-2) S: Ted Power (3) | Sixth | 4½ out |
| Monday, April 22 |
| » Lost to Dodgers (8-6), 3-2 | Candlestick Park (1-2) | 3-9 | Lost 7 |
| » W: Tom Niedenfuer (1-0) L: Dave LaPoint (0-3) | Sixth | 4½ out |
| Tuesday, April 23 |
| » Defeated Dodgers (8-7), 2-1 | Candlestick Park (2-2) | 4-9 | |
| » W: Mike Krukow (2-0) L: Fernando Valenzuela (2-2) | Fifth | 3½ out |
| Wednesday, April 24 |
| » Lost to Dodgers (9-7), 4-2 | Candlestick Park (2-3) | 4-10 | |
| » W: Tom Brennan (1-0) L: Bill Laskey (0-2) S: Ken Howell (3) | Sixth | 4½ out |
| Thursday, April 25 |
| » Defeated Reds (9-7), 7-3 | Candlestick Park (3-3) | 5-10 | |
| » W: Mark Davis (1-1) L: Tom Hume (0-1) | Sixth | 4 out |
| Friday, April 26 |
| » Defeated Reds (9-8), 7-6 | Candlestick Park (4-3) | 6-10 | Won 2 |
| » W: Vida Blue (2-0) L: Ted Power (0-1) | Fifth | 4 out |
| Saturday, April 27 |
| » Lost to Reds (10-8), 2-1 | Candlestick Park (4-4) | 6-11 | |
| » W: John Stuper (3-1) L: Dave LaPoint (0-4) | Sixth | 4 out |
| Sunday, April 28 |
| » Defeated Reds (10-9), 2-1 | Candlestick Park (5-4) | 7-11 | |
| » W: Greg Minton (1-1) L: Tom Hume (0-2) | Fifth | 3 out |
| Tuesday, April 30 |
| » Lost to Cubs (12-6), 3-1 | Wrigley Field (0-1) | 7-12 | |
| » W: Steve Trout (4-1) L: Bill Laskey (0-3) S: Lee Smith (5) | Fifth | 3 out |
| Wednesday, May 1 |
| » Lost to Cubs (13-6), 4-3 | Wrigley Field (0-2) | 7-13 | Lost 2 |
| » W: Dennis Eckersley (4-1) L: Scott Garrelts (0-1) | Sixth | 4 out |
| Friday, May 3 |
| » Lost to Cardinals (9-12), 8-1 | Busch Stadium II (0-1) | 7-14 | Lost 3 |
| » W: John Tudor (1-3) L: Mike Krukow (2-1) | Sixth | 5 out |
| Saturday, May 4 |
| » Lost to Cardinals (10-12), 6-4 | Busch Stadium II (0-2) | 7-15 | Lost 4 |
| » W: Kurt Kepshire (2-3) L: Atlee Hammaker (0-3) S: Jeff Lahti (1) | Fifth | 5 out |
| Sunday, May 5 |
| » Defeated Cardinals (10-13), 5-0 | Busch Stadium II (1-2) | 8-15 | |
| » W: Dave LaPoint (1-4) L: Joaquin Andujar (4-1) | Sixth | 4½ out |
| Monday, May 6 |
| » Defeated Pirates (8-15), 7-5 | Three Rivers Stadium (1-0) | 9-15 | Won 2 |
| » W: Bill Laskey (1-3) L: Jose DeLeon (0-5) S: Scott Garrelts (2) | Sixth | 4 out |
| Former Giant Kirby Higbe dies in Columbia, SC at the age of 71. |
| Tuesday, May 7 |
| » Defeated Pirates (8-16), 5-3 | Three Rivers Stadium (2-0) | 10-15 | Won 3 |
| » W: Jim Gott (2-0) L: Lee Tunnell (0-3) S: Scott Garrelts (3) | Sixth | 3½ out |
| Wednesday, May 8 |
| » Lost to Cubs (16-8), 1-0 | Candlestick Park (5-5) | 10-16 | |
| » W: Rick Sutcliffe (4-3) L: Mike Krukow (2-2) | Fifth | 4½ out |
| Thursday, May 9 |
| » Defeated Cubs (16-9), 1-0 | Candlestick Park (6-5) | 11-16 | |
| » W: Scott Garrelts (1-1) L: Warren Brusstar (0-1) | Fifth | 4½ out |
| Friday, May 10 |
| » Lost to Cardinals (13-15), 9-3 | Candlestick Park (6-6) | 11-17 | |
| » W: Joaquin Andujar (5-1) L: Dave LaPoint (1-5) S: Bill Campbell (1) | Sixth | 4½ out |
| Saturday, May 11 |
| » Lost to Cardinals (14-15), 9-4 | Candlestick Park (6-7) | 11-18 | Lost 2 |
| » W: Danny Cox (3-1) L: Bill Laskey (1-4) | Fifth | 5½ out |
| Sunday, May 12 |
| » Defeated Cardinals (14-16), 5-4 | Candlestick Park (7-7) | 12-18 | |
| » W: Scott Garrelts (2-1) L: Neil Allen (1-3) | Fifth | 5½ out |
| Tuesday, May 14 |
| » Defeated Pirates (9-21), 3-1 | Candlestick Park (8-7) | 13-18 | Won 2 |
| » W: Mike Krukow (3-2) L: Larry McWilliams (3-3) | Fifth | 5½ out |
| Wednesday, May 15 |
| » Lost to Pirates (10-21), 3-2 | Candlestick Park (8-8) | 13-19 | |
| » W: Don Robinson (2-0) L: Scott Garrelts (2-2) | Sixth | 5½ out |
| Friday, May 17 |
| » Lost to Mets (22-10), 3-2 | Shea Stadium (0-1) | 13-20 | Lost 2 |
| » W: Roger McDowell (4-1) L: Scott Garrelts (2-3) | Fifth | 5½ out |
| Saturday, May 18 |
| » Defeated Mets (22-11), 8-2 | Shea Stadium (1-1) | 14-20 | |
| » W: Mark Davis (2-1) L: Wes Gardner (0-1) | Fifth | 5½ out |
| Sunday, May 19 |
| » Lost to Mets (23-11), 3-2 | Shea Stadium (1-2) | 14-21 | |
| » W: Tom Gorman (3-1) L: Mark Davis (2-2) S: Roger McDowell (2) | Fifth | 6½ out |
| Monday, May 20 |
| » Lost to Phillies (14-22), 2-1 | Veteran's Stadium (0-1) | 14-22 | Lost 2 |
| » W: Steve Carlton (1-3) L: Vida Blue (2-1) S: Kent Tekulve (1) | Fifth | 7½ out |
| Tuesday, May 21 |
| » Lost to Phillies (15-22), 6-5 | Veteran's Stadium (0-2) | 14-23 | Lost 3 |
| » W: Shane Rawley (4-3) L: Atlee Hammaker (0-4) S: Kent Tekulve (2) | Sixth | 8 out |
| Wednesday, May 22 |
| » Defeated Phillies (15-23), 6-2 | Veteran's Stadium (1-2) | 15-23 | |
| » W: Dave LaPoint (2-5) L: Kevin Gross (3-5) S: Scott Garrelts (4) | Fifth | 8 out |
| Friday, May 24 |
| » Lost to Expos (23-17), 2-0 | Stade Olympique (0-1) | 15-24 | |
| » W: Joe Hesketh (5-2) L: Bill Laskey (1-5) S: Jeff Reardon (10) | Fifth | 9 out |
| Saturday, May 25 |
| » Lost to Expos (24-17), 3-1 | Stade Olympique (0-2) | 15-25 | Lost 2 |
| » W: Dan Schatzeder (2-0) L: Jim Gott (2-1) S: Jeff Reardon (11) | Fifth | 10 out |
| Sunday, May 26 |
| » Lost to Expos (25-17), 3-1 | Stade Olympique (0-3) | 15-26 | Lost 3 |
| » W: Bill Gullickson (6-4) L: Mike Krukow (3-3) S: Jeff Reardon (12) | Fifth | 11 out |
| Monday, May 27 |
| » Defeated Expos (25-18), 6-1 | Stade Olympique (1-3) | 16-26 | |
| » W: Atlee Hammaker (1-4) L: David Palmer (3-5) | Sixth | 10 out |
| Wednesday, May 29 |
| » Lost to Mets (26-15), 4-3 | Candlestick Park (8-9) | 16-27 | |
| » W: Ed Lynch (3-3) L: Mark Davis (2-3) S: Roger McDowell (3) | Fifth | 9½ out |
| Thursday, May 30 |
| » Lost to Mets (27-15), 2-1 | Candlestick Park (8-10) | 16-28 | Lost 2 |
| » W: Dwight Gooden (7-3) L: Jim Gott (2-2) | Fifth | 10½ out |
| Friday, May 31 |
| » Defeated Phillies (17-28), 4-3 | Candlestick Park (9-10) | 17-28 | |
| » W: Mike Krukow (4-3) L: Charles Hudson (1-5) S: Mark Davis (1) | Fifth | 10½ out |
| Saturday, June 1 |
| » Defeated Phillies (17-29), 2-1 | Candlestick Park (10-10) | 18-28 | Won 2 |
| » W: Atlee Hammaker (2-4) L: Steve Carlton (1-5) S: Greg Minton (1) | Sixth | 9½ out |
| Sunday, June 2 |
| » Defeated Phillies (17-30), 3-1 | Candlestick Park (11-10) | 19-28 | Won 3 |
| » W: Vida Blue (3-1) L: Shane Rawley (4-4) S: Mark Davis (2) | Fifth | 8½ out |
| Monday, June 3 |
| » Lost to Expos (29-21), 4-2 | Candlestick Park (11-11) | 19-29 | |
| » W: Randy St.claire (1-0) L: Frank Williams (0-2) | Sixth | 8½ out |
| Tuesday, June 4 |
| » Defeated Expos (29-22), 5-1 | Candlestick Park (12-11) | 20-29 | |
| » W: Jim Gott (3-2) L: Dan Schatzeder (2-2) | Fifth | 8½ out |
| Wednesday, June 5 |
| » Lost to Expos (30-22), 6-0 | Candlestick Park (12-12) | 20-30 | |
| » W: Mickey Mahler (1-0) L: Mike Krukow (4-4) | Sixth | 9½ out |
| Friday, June 7 |
| » Lost to Astros (27-25), 4-1 | Astrodome (0-1) | 20-31 | Lost 2 |
| » W: Mike Scott (4-2) L: Atlee Hammaker (2-5) S: Dave Smith (9) | Sixth | 11 out |
| Saturday, June 8 |
| » Lost to Astros (28-25), 4-1 | Astrodome (0-2) | 20-32 | Lost 3 |
| » W: Nolan Ryan (6-3) L: Bill Laskey (1-6) S: Dave Smith (10) | Sixth | 11 out |
| » Major-league debuts: Chris Jones (Astros) |
| Sunday, June 9 |
| » Lost to Astros (29-25), 5-0 | Astrodome (0-3) | 20-33 | Lost 4 |
| » W: Joe Niekro (3-6) L: Dave LaPoint (2-6) | Fifth | 12 out |
| Monday, June 10 |
| » Lost to Braves (23-30), 7-0 | Atlanta-Fulton County Stadium (0-1) | 20-34 | Lost 5 |
| » W: Zane Smith (3-4) L: Jim Gott (3-3) | Fifth | 13 out |
| Tuesday, June 11 |
| » Defeated Braves (23-31), 5-4 | Atlanta-Fulton County Stadium (1-1) | 21-34 | |
| » W: Frank Williams (1-2) L: Gene Garber (1-2) | Sixth | 12 out |
| Wednesday, June 12 |
| » Lost to Braves (24-31), 5-2 | Atlanta-Fulton County Stadium (1-2) | 21-35 | |
| » W: Rick Mahler (10-5) L: Atlee Hammaker (2-6) | Sixth | 12 out |
| Thursday, June 13 |
| » Lost to Padres (34-23), 3-0 | Candlestick Park (12-13) | 21-36 | Lost 2 |
| » W: Dave Dravecky (5-4) L: Bill Laskey (1-7) S: Rich Gossage (14) | Sixth | 13 out |
| Friday, June 14 |
| » Defeated Padres (34-24), 5-4 | Candlestick Park (13-13) | 22-36 | |
| » W: Mark Davis (3-3) L: Luis DeLeon (0-2) | Sixth | 12 out |
| Saturday, June 15 |
| » Lost to Padres (35-24), 1-0 | Candlestick Park (13-14) | 22-37 | |
| » W: La Marr Hoyt (8-4) L: Jim Gott (3-4) | Fifth | 13 out |
| Sunday, June 16 |
| » Defeated Padres (35-25), 7-3 | Candlestick Park (14-14) | 23-37 | |
| » W: Mike Krukow (5-4) L: Mark Thurmond (3-5) S: Mark Davis (3) | Fifth | 11 out |
| » Defeated Padres (35-26), 5-4 | Candlestick Park (15-14) | 24-37 | Won 2 |
| » W: Frank Williams (2-2) L: Mark Thurmond (3-6) | Fifth | 11 out |
| Monday, June 17 |
| » Defeated Reds (31-29), 4-0 | Candlestick Park (16-14) | 25-37 | Won 3 |
| » W: Atlee Hammaker (3-6) L: Jay Tibbs (4-8) | Fifth | 11 out |
| Tuesday, June 18 |
| » Lost to Reds (32-29), 6-1 | Candlestick Park (16-15) | 25-38 | |
| » W: Frank Pastore (2-0) L: Bill Laskey (1-8) | Sixth | 12 out |
| Wednesday, June 19 |
| » Defeated Reds (32-30), 5-2 | Candlestick Park (17-15) | 26-38 | |
| » W: Dave LaPoint (3-6) L: Mario Soto (8-6) S: Scott Garrelts (5) | Fifth | 11 out |
| Thursday, June 20 |
| » Lost to Padres (38-27), 6-5 | San Diego/Jack Murphy Stadium (0-3) | 26-39 | |
| » W: La Marr Hoyt (9-4) L: Mark Davis (3-4) S: Rich Gossage (16) | Fifth | 12 out |
| Friday, June 21 |
| » Lost to Padres (39-27), 6-1 | San Diego/Jack Murphy Stadium (0-4) | 26-40 | Lost 2 |
| » W: Ed Wojna (1-0) L: Vida Blue (3-2) | Sixth | 13 out |
| Saturday, June 22 |
| » Lost to Padres (40-27), 2-1 | San Diego/Jack Murphy Stadium (0-5) | 26-41 | Lost 3 |
| » W: Eric Show (6-4) L: Bill Laskey (1-9) S: Tim Stoddard (1) | Sixth | 14 out |
| Sunday, June 23 |
| » Lost to Padres (41-27), 6-1 | San Diego/Jack Murphy Stadium (0-6) | 26-42 | Lost 4 |
| » W: Dave Dravecky (7-4) L: Atlee Hammaker (3-7) | Sixth | 15 out |
| Tuesday, June 25 |
| » Lost to Reds (35-32), 7-6 | Riverfront Stadium (0-5) | 26-43 | Lost 5 |
| » W: John Stuper (6-5) L: Mark Davis (3-5) S: Ted Power (10) | Sixth | 15 out |
| Wednesday, June 26 |
| » Lost to Reds (36-32), 6-4 | Riverfront Stadium (0-6) | 26-44 | Lost 6 |
| » W: Tom Browning (7-5) L: Mike Krukow (5-5) S: Ted Power (11) | Fifth | 16 out |
| Thursday, June 27 |
| » Lost to Reds (37-32), 7-6 | Riverfront Stadium (0-7) | 26-45 | Lost 7 |
| » W: Ron Robinson (2-0) L: Jim Gott (3-5) S: Ted Power (12) | Sixth | 17 out |
| Friday, June 28 |
| » Lost to Astros (36-36), 3-1 | Candlestick Park (17-16) | 26-46 | Lost 8 |
| » W: Joe Niekro (6-7) L: Bill Laskey (1-10) S: Dave Smith (13) | Sixth | 17 out |
| Saturday, June 29 |
| » Lost to Astros (37-36), 8-1 | Candlestick Park (17-17) | 26-47 | Lost 9 |
| » W: Bob Knepper (8-4) L: Atlee Hammaker (3-8) | Sixth | 18 out |
| Sunday, June 30 |
| » Lost to Astros (38-36), 6-2 | Candlestick Park (17-18) | 26-48 | Lost 10 |
| » W: Mike Scott (6-4) L: Dave LaPoint (3-7) | Sixth | 17½ out |
| » Defeated Astros (38-37), 7-4 | Candlestick Park (18-18) | 27-48 | |
| » W: Vida Blue (4-2) L: Ron Mathis (3-3) S: Mark Davis (4) | Sixth | 17½ out |
| Monday, July 1 |
| » Lost to Braves (34-40), 4-1 | Candlestick Park (18-19) | 27-49 | |
| » W: Zane Smith (5-4) L: Mike Krukow (5-6) S: Bruce Sutter (15) | Fifth | 18½ out |
| Tuesday, July 2 |
| » Defeated Braves (34-41), 8-3 | Candlestick Park (19-19) | 28-49 | |
| » W: Jim Gott (4-5) L: Steve Bedrosian (5-7) S: Scott Garrelts (6) | Sixth | 17½ out |
| Thursday, July 4 |
| » Defeated Cubs (40-35), 6-4 | Wrigley Field (1-2) | 29-49 | Won 2 |
| » W: Scott Garrelts (3-3) L: Steve Trout (7-4) S: Greg Minton (2) | Sixth | 17½ out |
| Friday, July 5 |
| » Defeated Cubs (40-36), 12-6 | Wrigley Field (2-2) | 30-49 | Won 3 |
| » W: Vida Blue (5-2) L: Scott Sanderson (4-4) | Sixth | 16½ out |
| Saturday, July 6 |
| » Defeated Cubs (40-37), 6-4 | Wrigley Field (3-2) | 31-49 | Won 4 |
| » W: Scott Garrelts (4-3) L: Lee Smith (4-3) S: Mark Davis (5) | Sixth | 15½ out |
| Sunday, July 7 |
| » Lost to Cubs (41-37), 6-5 | Wrigley Field (3-3) | 31-50 | |
| » W: Warren Brusstar (2-1) L: Mark Davis (3-6) S: Lee Smith (18) | Sixth | 16½ out |
| Monday, July 8 |
| » Lost to Cardinals (47-32), 6-1 | Busch Stadium II (1-3) | 31-51 | Lost 2 |
| » W: Joaquin Andujar (15-3) L: Dave LaPoint (3-8) | Sixth | 17 out |
| Tuesday, July 9 |
| » Lost to Cardinals (48-32), 3-1 | Busch Stadium II (1-4) | 31-52 | Lost 3 |
| » W: Danny Cox (10-4) L: Bill Laskey (1-11) | Sixth | 17 out |
| Wednesday, July 10 |
| » Lost to Cardinals (49-32), 7-3 | Busch Stadium II (1-5) | 31-53 | Lost 4 |
| » W: Kurt Kepshire (6-6) L: Vida Blue (5-3) S: Jeff Lahti (7) | Sixth | 17 out |
| Thursday, July 11 |
| » Lost to Pirates (28-54), 6-4 | Three Rivers Stadium (2-1) | 31-54 | Lost 5 |
| » W: Cecilio Guante (2-1) L: Mike Krukow (5-7) | Sixth | 17 out |
| Friday, July 12 |
| » Lost to Pirates (29-54), 3-1 | Three Rivers Stadium (2-2) | 31-55 | Lost 6 |
| » W: Rick Reuschel (8-2) L: Jim Gott (4-6) S: John Candelaria (9) | Sixth | 18 out |
| Saturday, July 13 |
| » Defeated Pirates (29-55), 4-1 | Three Rivers Stadium (3-2) | 32-55 | |
| » W: Dave LaPoint (4-8) L: Jose DeLeon (2-13) | Sixth | 17½ out |
| Sunday, July 14 |
| » Defeated Pirates (29-56), 7-3 | Three Rivers Stadium (4-2) | 33-55 | Won 2 |
| » W: Bill Laskey (2-11) L: Rick Rhoden (5-10) S: Mark Davis (6) | Sixth | 16½ out |
| Thursday, July 18 |
| » Defeated Cubs (45-42), 1-0 | Candlestick Park (20-19) | 34-55 | Won 3 |
| » W: Mike Krukow (6-7) L: George Frazier (5-3) | Sixth | 16½ out |
| Friday, July 19 |
| » Lost to Cubs (46-42), 4-3 | Candlestick Park (20-20) | 34-56 | |
| » W: Lary Sorensen (2-2) L: Jim Gott (4-7) S: Lee Smith (20) | Sixth | 17½ out |
| Saturday, July 20 |
| » Lost to Cubs (47-42), 2-1 | Candlestick Park (20-21) | 34-57 | Lost 2 |
| » W: Dick Ruthven (4-6) L: Atlee Hammaker (3-9) S: Lee Smith (21) | Sixth | 18½ out |
| Sunday, July 21 |
| » Defeated Cubs (47-43), 2-1 | Candlestick Park (21-21) | 35-57 | |
| » W: Bill Laskey (3-11) L: Larry Gura (0-3) S: Greg Minton (3) | Sixth | 17½ out |
| Monday, July 22 |
| » Lost to Cardinals (54-36), 4-3 | Candlestick Park (21-22) | 35-58 | |
| » W: Joaquin Andujar (16-4) L: Dave LaPoint (4-9) S: Jeff Lahti (10) | Sixth | 17½ out |
| Tuesday, July 23 |
| » Lost to Cardinals (55-36), 6-3 | Candlestick Park (21-23) | 35-59 | Lost 2 |
| » W: Danny Cox (12-5) L: Mike Krukow (6-8) | Sixth | 18½ out |
| Wednesday, July 24 |
| » Lost to Cardinals (56-36), 4-0 | Candlestick Park (21-24) | 35-60 | Lost 3 |
| » W: John Tudor (11-8) L: Jim Gott (4-8) | Sixth | 19½ out |
| Thursday, July 25 |
| » Defeated Pirates (31-62), 4-3 | Candlestick Park (22-24) | 36-60 | |
| » W: Greg Minton (2-1) L: Cecilio Guante (2-2) | Sixth | 19½ out |
| Friday, July 26 |
| » Defeated Pirates (31-63), 3-1 | Candlestick Park (23-24) | 37-60 | Won 2 |
| » W: Bill Laskey (4-11) L: Lee Tunnell (1-7) S: Scott Garrelts (7) | Sixth | 19½ out |
| Saturday, July 27 |
| » Defeated Pirates (31-64), 8-3 | Candlestick Park (24-24) | 38-60 | Won 3 |
| » W: Dave LaPoint (5-9) L: Don Robinson (2-5) S: Greg Minton (4) | Sixth | 19½ out |
| Sunday, July 28 |
| » Defeated Pirates (31-65), 3-2 | Candlestick Park (25-24) | 39-60 | Won 4 |
| » W: Scott Garrelts (5-3) L: Cecilio Guante (2-3) | Sixth | 18½ out |
| Monday, July 29 |
| » Lost to Dodgers (57-40), 10-5 | Dodger Stadium (2-2) | 39-61 | |
| » W: Bob Welch (6-1) L: Vida Blue (5-4) | Sixth | 19½ out |
| Tuesday, July 30 |
| » Lost to Dodgers (58-40), 4-2 | Dodger Stadium (2-3) | 39-62 | Lost 2 |
| » W: Tom Niedenfuer (5-3) L: Greg Minton (2-2) | Sixth | 20½ out |
| Wednesday, July 31 |
| » Defeated Dodgers (58-41), 7-5 | Dodger Stadium (3-3) | 40-62 | |
| » W: Bill Laskey (5-11) L: Jerry Reuss (8-7) S: Scott Garrelts (8) | Sixth | 19½ out |
| Friday, August 2 |
| » Lost to Braves (45-56), 12-7 | Atlanta-Fulton County Stadium (1-3) | 40-63 | |
| » W: Gene Garber (2-3) L: Frank Williams (2-3) | Sixth | 20 out |
| Saturday, August 3 |
| » Defeated Braves (45-57), 7-5 | Atlanta-Fulton County Stadium (2-3) | 41-63 | |
| » W: Mike Krukow (7-8) L: Rick Mahler (15-9) S: Scott Garrelts (9) | Sixth | 20 out |
| Sunday, August 4 |
| » Lost to Braves (46-57), 5-4 | Atlanta-Fulton County Stadium (2-4) | 41-64 | |
| » W: Gene Garber (3-3) L: Mike Jeffcoat (0-1) | Sixth | 20 out |
| Monday, August 5 |
| » Lost to Astros (50-56), 7-5 | Astrodome (0-4) | 41-65 | Lost 2 |
| » W: Bob Knepper (9-9) L: Atlee Hammaker (3-10) S: Dave Smith (18) | Sixth | 21 out |
| Wednesday, August 7 |
| Former Giant Johnny Rucker dies in Moultrie, GA at the age of 69. |
| Thursday, August 8 |
| » Lost to Braves (47-58), 2-0 | Candlestick Park (25-25) | 41-66 | Lost 3 |
| » W: Rick Mahler (16-9) L: Greg Minton (2-3) | Sixth | 21 out |
| Friday, August 9 |
| » Lost to Braves (48-58), 6-5 | Candlestick Park (25-26) | 41-67 | Lost 4 |
| » W: Jeff Dedmon (5-1) L: Dave LaPoint (5-10) S: Bruce Sutter (18) | Sixth | 22 out |
| Saturday, August 10 |
| » Defeated Braves (48-59), 6-5 | Candlestick Park (26-26) | 42-67 | |
| » W: Scott Garrelts (6-3) L: Jeff Dedmon (5-2) | Sixth | 22 out |
| Sunday, August 11 |
| » Lost to Braves (49-59), 7-4 | Candlestick Park (26-27) | 42-68 | |
| » W: Joe Johnson (1-0) L: Frank Williams (2-4) S: Bruce Sutter (19) | Sixth | 23 out |
| Tuesday, August 13 |
| » Defeated Astros (51-60), 4-2 | Candlestick Park (27-27) | 43-68 | |
| » W: Mike Krukow (8-8) L: Joe Niekro (9-9) | Sixth | 23½ out |
| Wednesday, August 14 |
| » Lost to Astros (52-60), 7-5 | Candlestick Park (27-28) | 43-69 | |
| » W: Jeff Heathcock (1-1) L: Mark Davis (3-7) S: Dave Smith (19) | Sixth | 24½ out |
| Thursday, August 15 |
| » Lost to Astros (53-60), 4-1 | Candlestick Park (27-29) | 43-70 | Lost 2 |
| » W: Mike Scott (12-6) L: Dave LaPoint (5-11) | Sixth | 25½ out |
| Friday, August 16 |
| » Lost to Dodgers (69-44), 5-1 | Candlestick Park (27-30) | 43-71 | Lost 3 |
| » W: Jerry Reuss (11-7) L: Vida Blue (5-5) S: Ken Howell (12) | Sixth | 26½ out |
| Saturday, August 17 |
| » Defeated Dodgers (69-45), 5-2 | Candlestick Park (28-30) | 44-71 | |
| » W: Scott Garrelts (7-3) L: Carlos Diaz (3-2) | Sixth | 25½ out |
| Sunday, August 18 |
| » Defeated Dodgers (69-46), 2-1 | Candlestick Park (29-30) | 45-71 | Won 2 |
| » W: Mark Davis (4-7) L: Tom Niedenfuer (5-4) | Sixth | 24½ out |
| Tuesday, August 20 |
| » Lost to Mets (72-45), 3-0 | Shea Stadium (1-3) | 45-72 | |
| » W: Dwight Gooden (19-3) L: Jim Gott (4-9) | Sixth | 25½ out |
| Wednesday, August 21 |
| » Defeated Mets (72-46), 3-2 | Shea Stadium (2-3) | 46-72 | |
| » W: Dave LaPoint (6-11) L: Roger McDowell (6-5) S: Scott Garrelts (10) | Sixth | 25½ out |
| Thursday, August 22 |
| » Lost to Mets (73-46), 7-0 | Shea Stadium (2-4) | 46-73 | |
| » W: Terry Leach (2-1) L: Vida Blue (5-6) | Sixth | 25½ out |
| Friday, August 23 |
| » Defeated Phillies (55-65), 4-1 | Veteran's Stadium (2-2) | 47-73 | |
| » W: Atlee Hammaker (4-10) L: John Denny (8-10) S: Scott Garrelts (11) | Sixth | 25½ out |
| Saturday, August 24 |
| » Lost to Phillies (56-65), 9-2 | Veteran's Stadium (2-3) | 47-74 | |
| » W: Charles Hudson (7-11) L: Mike Krukow (8-9) | Sixth | 25½ out |
| Sunday, August 25 |
| » Lost to Phillies (57-65), 14-5 | Veteran's Stadium (2-4) | 47-75 | Lost 2 |
| » W: Dave Rucker (2-1) L: Jim Gott (4-10) | Sixth | 25½ out |
| Monday, August 26 |
| » Defeated Expos (69-56), 7-4 | Stade Olympique (2-3) | 48-75 | |
| » W: Dave LaPoint (7-11) L: Bill Laskey (5-14) S: Scott Garrelts (12) | Sixth | 25½ out |
| Former Giant Dick Wakefield dies in Redford, MI at the age of 65. |
| Tuesday, August 27 |
| » Defeated Expos (69-57), 6-1 | Stade Olympique (3-3) | 49-75 | Won 2 |
| » W: Greg Minton (3-3) L: Jeff Reardon (2-6) | Sixth | 25½ out |
| Thursday, August 29 |
| » Defeated Mets (75-51), 6-3 | Candlestick Park (30-30) | 50-75 | Won 3 |
| » W: Scott Garrelts (8-3) L: Terry Leach (2-2) | Sixth | 24½ out |
| Friday, August 30 |
| » Lost to Mets (76-51), 2-1 | Candlestick Park (30-31) | 50-76 | |
| » W: Ron Darling (13-5) L: Mike Krukow (8-10) | Sixth | 24½ out |
| Saturday, August 31 |
| » Defeated Mets (76-52), 3-2 | Candlestick Park (31-31) | 51-76 | |
| » W: Jim Gott (5-10) L: Dwight Gooden (20-4) S: Mark Davis (7) | Sixth | 23½ out |
| Sunday, September 1 |
| » Lost to Mets (77-52), 4-3 | Candlestick Park (31-32) | 51-77 | |
| » W: Doug Sisk (3-5) L: Mark Davis (4-8) S: Jesse Orosco (15) | Sixth | 23½ out |
| Monday, September 2 |
| » Lost to Phillies (63-66), 4-3 | Candlestick Park (31-33) | 51-78 | Lost 2 |
| » W: Don Carman (7-4) L: Mike Jeffcoat (0-2) S: Dave Shipanoff (3) | Sixth | 24½ out |
| Tuesday, September 3 |
| » Lost to Phillies (64-66), 4-3 | Candlestick Park (31-34) | 51-79 | Lost 3 |
| » W: Dave Shipanoff (1-0) L: Greg Minton (3-4) S: Freddie Toliver (1) | Sixth | 25½ out |
| » Major-league debuts: Matt Nokes (Giants) |
| Wednesday, September 4 |
| » Defeated Phillies (64-67), 4-3 | Candlestick Park (32-34) | 52-79 | |
| » W: Mark Davis (5-8) L: Freddie Toliver (0-1) | Sixth | 25½ out |
| Friday, September 6 |
| » Defeated Expos (71-62), 8-3 | Candlestick Park (33-34) | 53-79 | Won 2 |
| » W: Jim Gott (6-10) L: Bill Gullickson (13-10) | Sixth | 24½ out |
| Saturday, September 7 |
| » Lost to Expos (72-62), 7-1 | Candlestick Park (33-35) | 53-80 | |
| » W: Floyd Youmans (2-2) L: Dave LaPoint (7-12) S: Tim Burke (6) | Sixth | 25½ out |
| Sunday, September 8 |
| » Lost to Expos (73-62), 9-6 | Candlestick Park (33-36) | 53-81 | Lost 2 |
| » W: Gary Lucas (5-2) L: Scott Garrelts (8-4) S: Tim Burke (7) | Sixth | 25½ out |
| Monday, September 9 |
| » Lost to Astros (66-69), 4-2 | Astrodome (0-5) | 53-82 | Lost 3 |
| » W: Mike Scott (16-7) L: Atlee Hammaker (4-11) S: Dave Smith (22) | Sixth | 26½ out |
| Tuesday, September 10 |
| » Lost to Astros (67-69), 4-1 | Astrodome (0-6) | 53-83 | Lost 4 |
| » W: Bob Knepper (13-10) L: Mike Krukow (8-11) | Sixth | 28 out |
| Wednesday, September 11 |
| » Defeated Astros (67-70), 11-4 | Astrodome (1-6) | 54-83 | |
| » W: Jim Gott (7-10) L: Joe Niekro (9-12) | Sixth | 28½ out |
| » Lost to Astros (68-70), 10-9 | Astrodome (1-7) | 54-84 | |
| » W: Frank DiPino (2-6) L: Mark Davis (5-9) | Sixth | 28½ out |
| Thursday, September 12 |
| » Lost to Astros (69-70), 5-2 | Astrodome (1-8) | 54-85 | Lost 2 |
| » W: Charlie Kerfeld (2-2) L: Dave LaPoint (7-13) | Sixth | 28½ out |
| Friday, September 13 |
| » Defeated Braves (59-81), 9-3 | Atlanta-Fulton County Stadium (3-4) | 55-85 | |
| » W: Vida Blue (6-6) L: Len Barker (2-8) | Sixth | 28 out |
| Saturday, September 14 |
| » Defeated Braves (59-82), 3-1 | Atlanta-Fulton County Stadium (4-4) | 56-85 | Won 2 |
| » W: Greg Minton (4-4) L: Gene Garber (5-6) | Fifth | 28 out |
| Sunday, September 15 |
| » Lost to Braves (60-82), 4-1 | Atlanta-Fulton County Stadium (4-5) | 56-86 | |
| » W: Steve Bedrosian (7-12) L: Roger Mason (0-1) S: Bruce Sutter (23) | Sixth | 28 out |
| Monday, September 16 |
| » Lost to Reds (76-66), 7-6 | Riverfront Stadium (0-8) | 56-87 | Lost 2 |
| » W: John Stuper (7-5) L: Mark Davis (5-10) | Sixth | 28 out |
| Tuesday, September 17 |
| » Lost to Reds (77-66), 6-1 | Riverfront Stadium (0-9) | 56-88 | Lost 3 |
| » W: Andy McGaffigan (2-3) L: Dave LaPoint (7-14) | Sixth | 29 out |
| Wednesday, September 18 |
| » Defeated Padres (72-73), 9-6 | Candlestick Park (34-36) | 57-88 | |
| » Manager: Roger Craig |
| » W: Vida Blue (7-6) L: Mark Thurmond (6-10) S: Scott Garrelts (13) | Sixth | 28 out |
| Thursday, September 19 |
| » Lost to Padres (73-73), 11-3 | Candlestick Park (34-37) | 57-89 | |
| » W: Dave Dravecky (12-10) L: Atlee Hammaker (4-12) | Sixth | 28 out |
| Friday, September 20 |
| » Defeated Dodgers (85-62), 5-3 | Candlestick Park (35-37) | 58-89 | |
| » W: Greg Minton (5-4) L: Tom Niedenfuer (7-7) | Sixth | 27 out |
| Saturday, September 21 |
| » Lost to Dodgers (86-62), 11-2 | Candlestick Park (35-38) | 58-90 | |
| » W: Jerry Reuss (13-10) L: Mark Davis (5-11) | Sixth | 28 out |
| Sunday, September 22 |
| » Lost to Dodgers (87-62), 5-3 | Candlestick Park (35-39) | 58-91 | Lost 2 |
| » W: Orel Hershiser (17-3) L: Vida Blue (7-7) S: Tom Niedenfuer (16) | Sixth | 29 out |
| Monday, September 23 |
| » Defeated Padres (75-75), 7-2 | San Diego/Jack Murphy Stadium (1-6) | 59-91 | |
| » W: Atlee Hammaker (5-12) L: Mark Thurmond (6-11) | Sixth | 29 out |
| Tuesday, September 24 |
| » Lost to Padres (76-75), 4-3 | San Diego/Jack Murphy Stadium (1-7) | 59-92 | |
| » W: Dave Dravecky (13-10) L: Dave LaPoint (7-15) S: Rich Gossage (24) | Sixth | 30 out |
| Wednesday, September 25 |
| » Lost to Padres (77-75), 7-4 | San Diego/Jack Murphy Stadium (1-8) | 59-93 | Lost 2 |
| » W: La Marr Hoyt (16-8) L: Roger Mason (0-2) S: Rich Gossage (25) | Sixth | 30 out |
| Friday, September 27 |
| » Lost to Dodgers (90-63), 6-2 | Dodger Stadium (3-4) | 59-94 | Lost 3 |
| » W: Orel Hershiser (18-3) L: Vida Blue (7-8) | Fifth | 31 out |
| Saturday, September 28 |
| » Lost to Dodgers (91-63), 3-1 | Dodger Stadium (3-5) | 59-95 | Lost 4 |
| » W: Jerry Reuss (14-10) L: Dave LaPoint (7-16) S: Tom Niedenfuer (18) | Sixth | 32 out |
| Sunday, September 29 |
| » Lost to Dodgers (92-63), 7-2 | Dodger Stadium (3-6) | 59-96 | Lost 5 |
| » W: Bob Welch (13-4) L: Roger Mason (0-3) | Sixth | 33 out |
| Monday, September 30 |
| » Defeated Reds (86-69), 4-3 | Candlestick Park (36-39) | 60-96 | |
| » W: Scott Garrelts (9-4) L: Ted Power (7-6) | Sixth | 32 out |
| Tuesday, October 1 |
| » Lost to Reds (87-69), 7-6 | Candlestick Park (36-40) | 60-97 | |
| » W: Tom Hume (3-4) L: Scott Garrelts (9-5) S: John Franco (11) | Sixth | 33 out |
| Wednesday, October 2 |
| » Lost to Astros (80-78), 7-2 | Candlestick Park (36-41) | 60-98 | Lost 2 |
| » W: Bill Dawley (5-3) L: Mark Davis (5-12) | Sixth | 34 out |
| Thursday, October 3 |
| » Lost to Astros (81-78), 7-2 | Candlestick Park (36-42) | 60-99 | Lost 3 |
| » W: Jeff Heathcock (3-1) L: Dave LaPoint (7-17) | Sixth | 34 out |
| Friday, October 4 |
| » Defeated Braves (65-95), 1-0 | Candlestick Park (37-42) | 61-99 | |
| » W: Roger Mason (1-3) L: Rick Mahler (17-15) | Sixth | 33 out |
| Saturday, October 5 |
| » Defeated Braves (65-96), 7-1 | Candlestick Park (38-42) | 62-99 | Won 2 |
| » W: Vida Blue (8-8) L: Pascual Perez (1-13) | Sixth | 33 out |
| Sunday, October 6 |
| » Lost to Braves (66-96), 8-7 | Candlestick Park (38-43) | 62-100 | |
| » W: Jeff Dedmon (6-3) L: Scott Garrelts (9-6) S: Gene Garber (1) | Fifth | 33 out |
| Monday, November 25 |
| Former Giant Ray Jablonski dies in Chicago, IL at the age of 59. |
| Friday, December 6 |
| Former Giant Burleigh Grimes dies in Clear Lake, WI at the age of 93. |
| Tuesday, December 17 |
| Former Giant Ken O'Dea dies in Lima, NY at the age of 73. |
| Saturday, December 21 |
| Former Giant Joe Genewich dies in Lockport, NY at the age of 89. |
Game information provided by Retrosheet (www.retrosheet.org) |