| Sunday, January 9 |
| Former Red Sox Stan Spence dies in Kinston, NC at the age of 68. |
| Wednesday, March 30 |
| Former Red Sox Joe Cicero dies in Clearwater, FL at the age of 73. |
| Tuesday, April 5 |
| » Lost to Blue Jays (1-0), 7-1 | Fenway Park (0-1) | 0-1 | |
| » W: Dave Stieb (1-0) L: Dennis Eckersley (0-1) S: Roy Lee Jackson (1) | Second | 1 out |
| Thursday, April 7 |
| » Defeated Blue Jays (1-1), 7-4 | Fenway Park (1-1) | 1-1 | |
| » W: Bob Stanley (1-0) L: Luis Leal (0-1) | Second | ½ out |
| » Major-league debuts: Jim Acker (Blue Jays) |
| Friday, April 8 |
| » Defeated Rangers (3-1), 8-5 | Arlington Stadium (1-0) | 2-1 | Won 2 |
| » W: Luis Aponte (1-0) L: Mike Mason (0-1) | First | -- |
| Saturday, April 9 |
| » Lost to Rangers (4-1), 10-3 | Arlington Stadium (1-1) | 2-2 | |
| » W: Mike Smithson (1-0) L: Bob Ojeda (0-1) | Third | 1 out |
| Former Red Sox Bill Kennedy dies in Seattle, WA at the age of 63. |
| Sunday, April 10 |
| » Lost to Rangers (5-1), 9-7 | Arlington Stadium (1-2) | 2-3 | Lost 2 |
| » W: Charlie Hough (1-0) L: Bob Stanley (1-1) | Third | 1 out |
| Monday, April 11 |
| » Lost to Royals (3-2), 6-2 | Royals Stadium (0-1) | 2-4 | Lost 3 |
| » W: Dennis Leonard (1-1) L: Bruce Hurst (0-1) S: Dan Quisenberry (2) | Fourth | 1½ out |
| Former Red Sox Mike Menosky dies in Detroit, MI at the age of 89. |
| Tuesday, April 12 |
| » Lost to Royals (4-2), 5-1 | Royals Stadium (0-2) | 2-5 | Lost 4 |
| » W: Mike Armstrong (1-1) L: John Tudor (0-1) | Fifth | 2 out |
| Wednesday, April 13 |
| » Defeated Royals (4-3), 18-4 | Royals Stadium (1-2) | 3-5 | |
| » W: Mike Brown (1-0) L: Paul Splittorff (0-1) S: Bob Stanley (1) | Fifth | 1½ out |
| Friday, April 15 |
| » Defeated Rangers (6-3), 4-1 | Fenway Park (2-1) | 4-5 | Won 2 |
| » W: Dennis Eckersley (1-1) L: Jon Matlack (1-1) S: Bob Stanley (2) | Fifth | 1 out |
| Saturday, April 16 |
| » Defeated Rangers (6-4), 2-1 | Fenway Park (3-1) | 5-5 | Won 3 |
| » W: Bruce Hurst (1-1) L: Danny Darwin (0-1) S: Mark Clear (1) | Third | ½ out |
| Sunday, April 17 |
| » Lost to Rangers (7-4), 1-0 | Fenway Park (3-2) | 5-6 | |
| » W: Odell Jones (1-0) L: Bob Stanley (1-2) S: Dave Tobik (2) | Third | 1 out |
| Monday, April 18 |
| » Lost to Brewers (6-5), 14-0 | Fenway Park (3-3) | 5-7 | Lost 2 |
| » W: Don Sutton (2-1) L: Mike Brown (1-1) | Fourth | 2 out |
| Wednesday, April 20 |
| » Defeated Brewers (6-6), 5-4 | Fenway Park (4-3) | 6-7 | |
| » W: Mark Clear (1-0) L: Pete Ladd (0-1) | Third | 1½ out |
| Friday, April 22 |
| » Defeated Athletics (9-7), 3-1 | Oakland-Alameda County Stadium (1-0) | 7-7 | Won 2 |
| » W: Bruce Hurst (2-1) L: Bill Krueger (2-1) S: Bob Stanley (3) | Second | 1 out |
| Sunday, April 24 |
| » Defeated Athletics (9-8), 4-2 | Oakland-Alameda County Stadium (2-0) | 8-7 | Won 3 |
| » W: John Tudor (1-1) L: Mike Norris (2-1) S: Bob Stanley (4) | Second | ½ out |
| Tuesday, April 26 |
| » Lost to Mariners (7-14), 7-6 | Kingdome (0-1) | 8-8 | |
| » W: Gaylord Perry (2-2) L: Mike Brown (1-2) S: Bill Caudill (4) | Fourth | 1 out |
| Wednesday, April 27 |
| » Defeated Mariners (7-15), 2-1 | Kingdome (1-1) | 9-8 | |
| » W: Dennis Eckersley (2-1) L: Matt Young (2-3) S: Bob Stanley (5) | Third | 1 out |
| Friday, April 29 |
| » Defeated Angels (12-8), 6-5 | Anaheim Stadium (1-0) | 10-8 | Won 2 |
| » W: Luis Aponte (2-0) L: Luis Sanchez (1-1) S: Bob Stanley (6) | Second | ½ out |
| Saturday, April 30 |
| » Lost to Angels (13-8), 4-1 | Anaheim Stadium (1-1) | 10-9 | |
| » W: Doug Corbett (1-0) L: Mark Clear (1-1) | Second | ½ out |
| Sunday, May 1 |
| » Defeated Angels (13-9), 10-9 | Anaheim Stadium (2-1) | 11-9 | |
| » W: Bob Stanley (2-2) L: Andy Hassler (0-1) | Second | ½ out |
| Tuesday, May 3 |
| » Defeated Athletics (13-10), 3-1 | Fenway Park (5-3) | 12-9 | Won 2 |
| » W: Dennis Eckersley (3-1) L: Bill Krueger (2-3) S: Bob Stanley (7) | Second | ½ out |
| Wednesday, May 4 |
| » Defeated Athletics (13-11), 7-1 | Fenway Park (6-3) | 13-9 | Won 3 |
| » W: Bruce Hurst (3-1) L: Rick Langford (0-2) | First | -- |
| Friday, May 6 |
| » Defeated Mariners (9-19), 6-4 | Fenway Park (7-3) | 14-9 | Won 4 |
| » W: Luis Aponte (3-0) L: Ed Vande Berg (0-1) | First | -- |
| Saturday, May 7 |
| » Defeated Mariners (9-20), 8-0 | Fenway Park (8-3) | 15-9 | Won 5 |
| » W: Mike Brown (2-2) L: Bob Stoddard (2-4) | First | -- |
| Sunday, May 8 |
| » Lost to Mariners (10-20), 4-2 | Fenway Park (8-4) | 15-10 | |
| » W: Matt Young (3-3) L: Doug Bird (0-1) S: Bill Caudill (5) | First | -- |
| Monday, May 9 |
| » Defeated Angels (16-12), 8-2 | Fenway Park (9-4) | 16-10 | |
| » W: Bob Stanley (3-2) L: Tommy John (2-2) | First | -- |
| Tuesday, May 10 |
| » Lost to Angels (17-12), 6-5 | Fenway Park (9-5) | 16-11 | |
| » W: Luis Sanchez (4-1) L: Luis Aponte (3-1) S: Mike Witt (3) | First | -- |
| Wednesday, May 11 |
| » Lost to Angels (18-12), 3-1 | Fenway Park (9-6) | 16-12 | Lost 2 |
| » W: Bruce Kison (4-1) L: John Tudor (1-2) | Second | ½ out |
| Thursday, May 12 |
| » Defeated Brewers (15-13), 5-3 | County Stadium (1-0) | 17-12 | |
| » W: Mike Brown (3-2) L: Mike Caldwell (2-4) S: Bob Stanley (8) | First | -- |
| Saturday, May 14 |
| » Lost to Brewers (16-13), 8-7 | County Stadium (1-1) | 17-13 | |
| » W: Bob Gibson (1-0) L: Mark Clear (1-2) | Second | 1½ out |
| Sunday, May 15 |
| » Defeated Brewers (16-14), 6-1 | County Stadium (2-1) | 18-13 | |
| » W: Bob Ojeda (1-1) L: Moose Haas (1-1) S: Luis Aponte (1) | Second | ½ out |
| Tuesday, May 17 |
| » Defeated Royals (14-16), 4-1 | Fenway Park (10-6) | 19-13 | Won 2 |
| » W: John Tudor (2-2) L: Larry Gura (4-4) S: Bob Stanley (9) | Second | 1 out |
| Wednesday, May 18 |
| » Lost to Royals (15-16), 2-1 | Fenway Park (10-7) | 19-14 | |
| » W: Dennis Leonard (5-3) L: Mike Brown (3-3) | Second | 2 out |
| Thursday, May 19 |
| » Defeated Twins (16-22), 4-1 | Fenway Park (11-7) | 20-14 | |
| » W: Doug Bird (1-1) L: Bobby Castillo (1-3) S: Luis Aponte (2) | Second | 2 out |
| Friday, May 20 |
| » Lost to Twins (17-22), 10-4 | Fenway Park (11-8) | 20-15 | |
| » W: Ken Schrom (2-0) L: Bruce Hurst (3-2) S: Rick Lysander (2) | Second | 2 out |
| Saturday, May 21 |
| » Defeated Twins (17-23), 11-4 | Fenway Park (12-8) | 21-15 | |
| » W: Bob Ojeda (2-1) L: Brad Havens (3-5) | Second | 1 out |
| Sunday, May 22 |
| » Lost to Twins (18-23), 4-3 | Fenway Park (12-9) | 21-16 | |
| » W: Ron Davis (2-1) L: Luis Aponte (3-2) | Second | 1 out |
| Monday, May 23 |
| » Defeated White Sox (15-22), 6-4 | Comiskey Park I (1-0) | 22-16 | |
| » W: Mike Brown (4-3) L: Richard Dotson (4-5) | First | -- |
| Tuesday, May 24 |
| » Lost to White Sox (16-22), 12-4 | Comiskey Park I (1-1) | 22-17 | |
| » W: Jerry Koosman (2-0) L: Doug Bird (1-2) S: Dick Tidrow (3) | Second | 1 out |
| Wednesday, May 25 |
| » Defeated White Sox (16-23), 2-0 | Comiskey Park I (2-1) | 23-17 | |
| » W: Bruce Hurst (4-2) L: Dennis Lamp (3-4) | First | -- |
| Thursday, May 26 |
| » Defeated Blue Jays (23-18), 7-2 | Exhibition Stadium (1-0) | 24-17 | Won 2 |
| » W: Bob Stanley (4-2) L: Dave Stieb (8-3) | First | -- |
| Friday, May 27 |
| » Defeated Blue Jays (23-19), 2-0 | Exhibition Stadium (2-0) | 25-17 | Won 3 |
| » W: John Tudor (3-2) L: Jim Clancy (4-3) | First | -- |
| Saturday, May 28 |
| » Lost to Blue Jays (24-19), 9-5 | Exhibition Stadium (2-1) | 25-18 | |
| » W: Roy Lee Jackson (4-1) L: Luis Aponte (3-3) S: Joey McLaughlin (4) | First | -- |
| Sunday, May 29 |
| » Lost to Blue Jays (25-19), 6-1 | Exhibition Stadium (2-2) | 25-19 | Lost 2 |
| » W: Jim Gott (2-4) L: Dennis Eckersley (3-2) | First | -- |
| Monday, May 30 |
| » Lost to White Sox (20-24), 6-4 | Fenway Park (12-10) | 25-20 | Lost 3 |
| » W: Britt Burns (2-2) L: Bruce Hurst (4-3) S: Salome Barojas (3) | Second | 1 out |
| Tuesday, May 31 |
| » Defeated White Sox (20-25), 2-1 | Fenway Park (13-10) | 26-20 | |
| » W: Bob Ojeda (3-1) L: Floyd Bannister (2-7) S: Bob Stanley (10) | Second | ½ out |
| Wednesday, June 1 |
| » Lost to White Sox (21-25), 8-3 | Fenway Park (13-11) | 26-21 | |
| » W: La Marr Hoyt (5-6) L: John Tudor (3-3) | Second | ½ out |
| Friday, June 3 |
| » Defeated Twins (22-30), 6-3 | Hubert H. Humphrey Metrodome (1-0) | 27-21 | |
| » W: Oil Can Boyd (1-0) L: Albert Williams (2-7) S: Bob Stanley (11) | First | -- |
| Saturday, June 4 |
| » Defeated Twins (22-31), 8-6 | Hubert H. Humphrey Metrodome (2-0) | 28-21 | Won 2 |
| » W: Dennis Eckersley (4-2) L: Frank Viola (2-3) S: Luis Aponte (3) | First | -- |
| Sunday, June 5 |
| » Lost to Twins (23-31), 10-4 | Hubert H. Humphrey Metrodome (2-1) | 28-22 | |
| » W: Brad Havens (4-5) L: Bruce Hurst (4-4) | First | -- |
| » Major-league debuts: Greg Gagne (Twins) |
| Monday, June 6 |
| » Lost to Tigers (26-25), 11-6 | Fenway Park (13-12) | 28-23 | Lost 2 |
| » W: Juan Berenguer (2-0) L: Bob Stanley (4-3) S: Aurelio Lopez (8) | Second | 1 out |
| Tuesday, June 7 |
| » Lost to Tigers (27-25), 4-2 | Fenway Park (13-13) | 28-24 | Lost 3 |
| » W: Milt Wilcox (6-6) L: John Tudor (3-4) | Second | 2 out |
| Wednesday, June 8 |
| » Lost to Tigers (28-25), 6-3 | Fenway Park (13-14) | 28-25 | Lost 4 |
| » W: Jack Morris (5-5) L: Oil Can Boyd (1-1) | Third | 3 out |
| Thursday, June 9 |
| » Lost to Tigers (29-25), 8-2 | Fenway Park (13-15) | 28-26 | Lost 5 |
| » W: Dan Petry (6-3) L: Dennis Eckersley (4-3) | Third | 4 out |
| Friday, June 10 |
| » Lost to Orioles (34-23), 3-0 | Fenway Park (13-16) | 28-27 | Lost 6 |
| » W: Storm Davis (4-3) L: Bruce Hurst (4-5) | Fourth | 5 out |
| Saturday, June 11 |
| » Lost to Orioles (35-23), 10-6 | Fenway Park (13-17) | 28-28 | Lost 7 |
| » W: Scott McGregor (8-3) L: Bob Ojeda (3-2) | Fourth | 6 out |
| Sunday, June 12 |
| » Defeated Orioles (35-24), 7-6 | Fenway Park (14-17) | 29-28 | |
| » W: Bob Stanley (5-3) L: Tippy Martinez (3-2) | Fourth | 5 out |
| Tuesday, June 14 |
| » Defeated Tigers (32-27), 6-2 | Tiger Stadium (1-0) | 30-28 | Won 2 |
| » W: Mike Brown (5-3) L: Dan Petry (6-4) S: Bob Stanley (12) | Fourth | 5 out |
| Wednesday, June 15 |
| » Lost to Tigers (33-27), 4-2 | Tiger Stadium (1-1) | 30-29 | |
| » W: Dave Rozema (4-0) L: Dennis Eckersley (4-4) S: Aurelio Lopez (10) | Fourth | 6 out |
| Thursday, June 16 |
| » Lost to Tigers (34-27), 10-2 | Tiger Stadium (1-2) | 30-30 | Lost 2 |
| » W: Juan Berenguer (3-0) L: Bruce Hurst (4-6) | Fifth | 6 out |
| Friday, June 17 |
| » Defeated Orioles (37-26), 5-3 | Memorial Stadium (1-0) | 31-30 | |
| » W: Bob Ojeda (4-2) L: Dennis Martinez (4-10) S: Bob Stanley (13) | Fifth | 5 out |
| Saturday, June 18 |
| » Defeated Orioles (37-27), 3-2 | Memorial Stadium (2-0) | 32-30 | Won 2 |
| » W: John Tudor (4-4) L: Tippy Martinez (4-3) | Fifth | 4 out |
| Sunday, June 19 |
| » Lost to Orioles (38-27), 6-3 | Memorial Stadium (2-1) | 32-31 | |
| » W: Jim Palmer (2-1) L: Mike Brown (5-4) | Fifth | 5 out |
| Monday, June 20 |
| » Defeated Indians (29-36), 6-3 | Fenway Park (15-17) | 33-31 | |
| » W: Dennis Eckersley (5-4) L: Juan Eichelberger (3-5) S: Bob Stanley (14) | Fifth | 4½ out |
| Tuesday, June 21 |
| » Lost to Indians (30-36), 3-1 | Fenway Park (15-18) | 33-32 | |
| » W: Bert Blyleven (5-6) L: Bruce Hurst (4-7) | Fifth | 5½ out |
| Wednesday, June 22 |
| » Lost to Indians (31-36), 9-4 | Fenway Park (15-19) | 33-33 | Lost 2 |
| » W: Len Barker (5-7) L: Bob Ojeda (4-3) | Fifth | 5½ out |
| Thursday, June 23 |
| » Lost to Indians (32-36), 5-4 | Fenway Park (15-20) | 33-34 | Lost 3 |
| » W: Rick Sutcliffe (9-2) L: Doug Bird (1-3) S: Neal Heaton (5) | Fifth | 6 out |
| Friday, June 24 |
| » Defeated Yankees (35-32), 5-4 | Fenway Park (16-20) | 34-34 | |
| » W: John Tudor (5-4) L: Dave Righetti (8-3) S: Bob Stanley (15) | Fourth | 5 out |
| Saturday, June 25 |
| » Lost to Yankees (36-32), 4-1 | Fenway Park (16-21) | 34-35 | |
| » W: Jay Howell (1-3) L: Dennis Eckersley (5-5) S: Rich Gossage (8) | Third | 5 out |
| Sunday, June 26 |
| » Defeated Yankees (36-33), 12-5 | Fenway Park (17-21) | 35-35 | |
| » W: Bruce Hurst (5-7) L: Matt Keough (3-4) S: Bob Stanley (16) | Fourth | 5 out |
| Tuesday, June 28 |
| » Defeated Indians (32-40), 11-3 | Cleveland Stadium (1-0) | 36-35 | Won 2 |
| » W: Mark Clear (2-2) L: Rick Sutcliffe (9-3) | Third | 4 out |
| Wednesday, June 29 |
| » Lost to Indians (33-40), 5-3 | Cleveland Stadium (1-1) | 36-36 | |
| » W: Len Barker (6-7) L: Bob Stanley (5-4) S: Neal Heaton (6) | Fourth | 4½ out |
| » Defeated Indians (33-41), 11-10 | Cleveland Stadium (2-1) | 37-36 | |
| » W: John Henry Johnson (1-0) L: Bud Anderson (0-1) S: Doug Bird (1) | Fourth | 4½ out |
| Friday, July 1 |
| » Lost to Yankees (40-33), 12-8 | Yankee Stadium (0-1) | 37-37 | |
| » W: Bob Shirley (3-5) L: John Henry Johnson (1-1) | Sixth | 5 out |
| Saturday, July 2 |
| » Defeated Yankees (40-34), 10-4 | Yankee Stadium (1-1) | 38-37 | |
| » W: Bruce Hurst (6-7) L: Matt Keough (3-5) | Fifth | 5 out |
| Sunday, July 3 |
| » Defeated Yankees (40-35), 7-3 | Yankee Stadium (2-1) | 39-37 | Won 2 |
| » W: Bob Ojeda (5-3) L: Shane Rawley (7-7) S: Mark Clear (2) | Fifth | 4 out |
| Monday, July 4 |
| » Lost to Yankees (41-35), 4-0 | Yankee Stadium (2-2) | 39-38 | |
| » W: Dave Righetti (10-3) L: John Tudor (5-5) | Fifth | 4½ out |
| Friday, July 8 |
| » Lost to Angels (43-36), 9-3 | Fenway Park (17-22) | 39-39 | Lost 2 |
| » W: Bruce Kison (8-2) L: Dennis Eckersley (5-6) | Fourth | 5½ out |
| Saturday, July 9 |
| » Defeated Angels (43-37), 10-3 | Fenway Park (18-22) | 40-39 | |
| » W: John Tudor (6-5) L: Ken Forsch (8-5) | Third | 5½ out |
| Sunday, July 10 |
| » Lost to Angels (44-37), 5-3 | Fenway Park (18-23) | 40-40 | |
| » W: Tommy John (7-5) L: Bruce Hurst (6-8) S: Luis Sanchez (4) | Fourth | 6½ out |
| Monday, July 11 |
| » Defeated Mariners (32-53), 6-5 | Fenway Park (19-23) | 41-40 | |
| » W: Luis Aponte (4-3) L: Mike Stanton (0-2) | Fourth | 6½ out |
| Tuesday, July 12 |
| » Lost to Mariners (33-53), 3-2 | Fenway Park (19-24) | 41-41 | |
| » W: Bryan Clark (4-2) L: Mike Brown (5-5) S: Bill Caudill (16) | Fifth | 7½ out |
| Wednesday, July 13 |
| » Lost to Mariners (34-53), 6-4 | Fenway Park (19-25) | 41-42 | Lost 2 |
| » W: Jim Beattie (8-5) L: Dennis Eckersley (5-7) S: Bill Caudill (17) | Fifth | 7½ out |
| Thursday, July 14 |
| » Defeated Athletics (38-49), 9-4 | Fenway Park (20-25) | 42-42 | |
| » W: John Tudor (7-5) L: Steve McCatty (3-4) S: Bob Stanley (17) | Fifth | 7½ out |
| Friday, July 15 |
| » Defeated Athletics (38-50), 10-7 | Fenway Park (21-25) | 43-42 | Won 2 |
| » W: Mark Clear (3-2) L: Tom Burgmeier (4-5) | Sixth | 7½ out |
| Saturday, July 16 |
| » Lost to Athletics (39-50), 12-5 | Fenway Park (21-26) | 43-43 | |
| » W: Keith Atherton (1-0) L: Bob Stanley (5-5) | Sixth | 8½ out |
| Sunday, July 17 |
| » Lost to Athletics (40-50), 13-9 | Fenway Park (21-27) | 43-44 | Lost 2 |
| » W: Chris Codiroli (6-6) L: Mark Clear (3-3) | Sixth | 8½ out |
| Monday, July 18 |
| » Defeated Angels (45-44), 7-2 | Anaheim Stadium (3-1) | 44-44 | |
| » W: Dennis Eckersley (6-7) L: Bruce Kison (8-4) S: Bob Stanley (18) | Fifth | 8½ out |
| Tuesday, July 19 |
| » Lost to Angels (46-44), 6-1 | Anaheim Stadium (3-2) | 44-45 | |
| » W: Ken Forsch (9-6) L: John Tudor (7-6) | Sixth | 8½ out |
| Wednesday, July 20 |
| » Defeated Angels (46-45), 6-4 | Anaheim Stadium (4-2) | 45-45 | |
| » W: Bob Stanley (6-5) L: Tommy John (7-7) | Fourth | 7½ out |
| Thursday, July 21 |
| » Defeated Mariners (36-59), 14-13 | Kingdome (2-1) | 46-45 | Won 2 |
| » W: John Henry Johnson (2-1) L: Ed Vande Berg (2-3) S: Bob Stanley (19) | Fifth | 6½ out |
| Friday, July 22 |
| » Defeated Mariners (36-60), 5-4 | Kingdome (3-1) | 47-45 | Won 3 |
| » W: Mike Brown (6-5) L: Ed Vande Berg (2-4) S: John Henry Johnson (1) | Sixth | 6½ out |
| Saturday, July 23 |
| » Lost to Mariners (37-60), 5-0 | Kingdome (3-2) | 47-46 | |
| » W: Bob Stoddard (5-10) L: Dennis Eckersley (6-8) | Sixth | 7½ out |
| » Major-league debuts: Al Chambers (Mariners) |
| Sunday, July 24 |
| » Defeated Mariners (37-61), 6-0 | Kingdome (4-2) | 48-46 | |
| » W: John Tudor (8-6) L: Glenn Abbott (3-3) | Fifth | 6½ out |
| Monday, July 25 |
| » Defeated Athletics (43-55), 3-0 | Oakland-Alameda County Stadium (3-0) | 49-46 | Won 2 |
| » W: Bruce Hurst (7-8) L: Chris Codiroli (7-7) | Fourth | 5½ out |
| » Major-league debuts: Donnie Hill (Athletics) |
| Tuesday, July 26 |
| » Lost to Athletics (44-55), 9-2 | Oakland-Alameda County Stadium (3-1) | 49-47 | |
| » W: Tom Underwood (6-5) L: Bob Stanley (6-6) | Fifth | 6 out |
| » Defeated Athletics (44-56), 5-3 | Oakland-Alameda County Stadium (4-1) | 50-47 | |
| » W: Bob Stanley (7-6) L: Tom Burgmeier (5-6) | Fifth | 6 out |
| Wednesday, July 27 |
| » Lost to Athletics (45-56), 7-6 | Oakland-Alameda County Stadium (4-2) | 50-48 | |
| » W: Bill Krueger (7-6) L: Mike Brown (6-6) S: Keith Atherton (1) | Sixth | 7 out |
| Friday, July 29 |
| » Lost to Brewers (54-43), 11-5 | Fenway Park (21-28) | 50-49 | Lost 2 |
| » W: Bob McClure (8-7) L: Dennis Eckersley (6-9) S: Tom Tellmann (7) | Sixth | 8 out |
| Saturday, July 30 |
| » Defeated Brewers (54-44), 10-5 | Fenway Park (22-28) | 51-49 | |
| » W: John Tudor (9-6) L: Don Sutton (7-7) | Sixth | 8 out |
| Sunday, July 31 |
| » Lost to Brewers (55-44), 7-5 | Fenway Park (22-29) | 51-50 | |
| » W: Moose Haas (8-2) L: Bob Stanley (7-7) S: Pete Ladd (10) | Sixth | 9 out |
| Monday, August 1 |
| » Lost to Brewers (56-44), 6-2 | Fenway Park (22-30) | 51-51 | Lost 2 |
| » W: Chuck Porter (3-5) L: Bob Ojeda (5-4) S: Tom Tellmann (8) | Sixth | 9½ out |
| Tuesday, August 2 |
| » Defeated Rangers (49-54), 6-5 | Arlington Stadium (2-2) | 52-51 | |
| » W: Oil Can Boyd (2-1) L: Charlie Hough (8-10) S: Bob Stanley (20) | Sixth | 8 out |
| Wednesday, August 3 |
| » Defeated Rangers (49-55), 5-4 | Arlington Stadium (3-2) | 53-51 | Won 2 |
| » W: Luis Aponte (5-3) L: Victor Cruz (0-1) S: Mark Clear (3) | Sixth | 8 out |
| Thursday, August 4 |
| » Lost to Rangers (50-55), 6-1 | Arlington Stadium (3-3) | 53-52 | |
| » W: Rick Honeycutt (14-6) L: John Tudor (9-7) | Sixth | 9 out |
| Friday, August 5 |
| » Defeated Royals (49-53), 5-4 | Royals Stadium (2-2) | 54-52 | |
| » W: Bruce Hurst (8-8) L: Mike Armstrong (5-6) S: Bob Stanley (21) | Sixth | 9 out |
| Saturday, August 6 |
| » Lost to Royals (50-53), 4-0 | Royals Stadium (2-3) | 54-53 | |
| » W: Eric Rasmussen (1-0) L: Bob Ojeda (5-5) | Sixth | 9 out |
| Sunday, August 7 |
| » Lost to Royals (51-53), 1-0 | Royals Stadium (2-4) | 54-54 | Lost 2 |
| » W: Gaylord Perry (5-12) L: Oil Can Boyd (2-2) S: Dan Quisenberry (28) | Sixth | 9 out |
| Monday, August 8 |
| » Lost to Rangers (54-56), 12-7 | Fenway Park (22-31) | 54-55 | Lost 3 |
| » W: John Butcher (3-3) L: Bob Stanley (7-8) | Sixth | 9 out |
| Tuesday, August 9 |
| » Defeated Rangers (54-57), 6-4 | Fenway Park (23-31) | 55-55 | |
| » W: John Tudor (10-7) L: Rick Honeycutt (14-7) | Sixth | 8 out |
| Wednesday, August 10 |
| » Defeated Rangers (54-58), 4-2 | Fenway Park (24-31) | 56-55 | Won 2 |
| » W: Bruce Hurst (9-8) L: Mike Smithson (7-11) S: Bob Stanley (22) | Fifth | 7 out |
| Saturday, August 13 |
| » Lost to Royals (54-55), 5-4 | Fenway Park (24-32) | 56-56 | |
| » W: Gaylord Perry (6-12) L: Luis Aponte (5-4) S: Dan Quisenberry (30) | Sixth | 7½ out |
| » Defeated Royals (54-56), 12-3 | Fenway Park (25-32) | 57-56 | |
| » W: Oil Can Boyd (3-2) L: Eric Rasmussen (1-1) | Sixth | 7½ out |
| Sunday, August 14 |
| » Defeated Royals (54-57), 4-3 | Fenway Park (26-32) | 58-56 | Won 2 |
| » W: Bob Stanley (8-8) L: Steve Renko (5-10) | Sixth | 7 out |
| » Lost to Royals (55-57), 6-3 | Fenway Park (26-33) | 58-57 | |
| » W: Keith Creel (2-4) L: John Tudor (10-8) S: Dan Quisenberry (31) | Sixth | 7 out |
| Monday, August 15 |
| » Lost to Brewers (65-51), 2-0 | County Stadium (2-2) | 58-58 | Lost 2 |
| » W: Moose Haas (11-2) L: Bruce Hurst (9-9) S: Pete Ladd (14) | Fifth | 8 out |
| Tuesday, August 16 |
| » Lost to Brewers (66-51), 4-3 | County Stadium (2-3) | 58-59 | Lost 3 |
| » W: Jim Slaton (10-5) L: Mark Clear (3-4) | Sixth | 8 out |
| Former Red Sox Earl Averill dies in Everett, WA at the age of 82. |
| Wednesday, August 17 |
| » Lost to Brewers (67-51), 4-3 | County Stadium (2-4) | 58-60 | Lost 4 |
| » W: Tom Tellmann (8-3) L: Bob Ojeda (5-6) | Sixth | 10 out |
| » Lost to Brewers (68-51), 5-1 | County Stadium (2-5) | 58-61 | Lost 5 |
| » W: Tom Candiotti (1-0) L: John Henry Johnson (2-2) | Sixth | 10 out |
| Friday, August 19 |
| » Lost to Blue Jays (68-53), 8-7 | Fenway Park (26-34) | 58-62 | Lost 6 |
| » W: Jim Acker (3-1) L: Mark Clear (3-5) S: Roy Lee Jackson (4) | Sixth | 11 out |
| Saturday, August 20 |
| » Defeated Blue Jays (68-54), 5-2 | Fenway Park (27-34) | 59-62 | |
| » W: Dennis Eckersley (7-9) L: Dave Stieb (13-11) S: Bob Stanley (23) | Sixth | 11 out |
| Sunday, August 21 |
| » Lost to Blue Jays (69-54), 7-3 | Fenway Park (27-35) | 59-63 | |
| » W: Jim Gott (7-10) L: Bruce Hurst (9-10) | Sixth | 11 out |
| Monday, August 22 |
| » Defeated Blue Jays (69-55), 4-2 | Fenway Park (28-35) | 60-63 | |
| » W: Bob Ojeda (6-6) L: Doyle Alexander (0-8) S: Bob Stanley (24) | Sixth | 11 out |
| Tuesday, August 23 |
| » Lost to Twins (54-72), 3-2 | Hubert H. Humphrey Metrodome (2-2) | 60-64 | |
| » W: Albert Williams (9-11) L: Oil Can Boyd (3-3) S: Ron Davis (24) | Sixth | 11 out |
| Wednesday, August 24 |
| » Lost to Twins (55-72), 8-7 | Hubert H. Humphrey Metrodome (2-3) | 60-65 | Lost 2 |
| » W: Len Whitehouse (7-1) L: Bob Stanley (8-9) S: Ron Davis (25) | Sixth | 12 out |
| Thursday, August 25 |
| » Lost to Twins (56-72), 5-2 | Hubert H. Humphrey Metrodome (2-4) | 60-66 | Lost 3 |
| » W: Frank Viola (7-11) L: Dennis Eckersley (7-10) | Sixth | 13 out |
| Friday, August 26 |
| » Defeated White Sox (70-57), 3-1 | Comiskey Park I (3-1) | 61-66 | |
| » W: Bruce Hurst (10-10) L: Floyd Bannister (12-10) S: Bob Stanley (25) | Sixth | 12½ out |
| Saturday, August 27 |
| » Lost to White Sox (71-57), 2-1 | Comiskey Park I (3-2) | 61-67 | |
| » W: La Marr Hoyt (17-10) L: Bob Ojeda (6-7) | Sixth | 13½ out |
| Sunday, August 28 |
| » Lost to White Sox (72-57), 6-2 | Comiskey Park I (3-3) | 61-68 | Lost 2 |
| » W: Jerry Koosman (10-6) L: Oil Can Boyd (3-4) S: Dennis Lamp (11) | Sixth | 14½ out |
| Monday, August 29 |
| » Lost to Blue Jays (72-59), 5-1 | Exhibition Stadium (2-3) | 61-69 | Lost 3 |
| » W: Jim Clancy (14-7) L: John Tudor (10-9) | Sixth | 15 out |
| » Defeated Blue Jays (72-60), 8-7 | Exhibition Stadium (3-3) | 62-69 | |
| » W: Mark Clear (4-5) L: Randy Moffitt (6-2) S: Bob Stanley (26) | Sixth | 15 out |
| Tuesday, August 30 |
| » Defeated Blue Jays (72-61), 5-4 | Exhibition Stadium (4-3) | 63-69 | Won 2 |
| » W: John Henry Johnson (3-2) L: Roy Lee Jackson (8-3) S: Mark Clear (4) | Sixth | 15 out |
| Thursday, September 1 |
| » Lost to Twins (58-76), 11-0 | Fenway Park (28-36) | 63-70 | |
| » W: Albert Williams (10-12) L: Dennis Eckersley (7-11) | Fifth | 15 out |
| » Defeated Twins (58-77), 9-3 | Fenway Park (29-36) | 64-70 | |
| » W: Bob Ojeda (7-7) L: Rick Lysander (4-11) | Fifth | 15 out |
| Friday, September 2 |
| » Defeated White Sox (76-58), 5-1 | Fenway Park (30-36) | 65-70 | Won 2 |
| » W: Oil Can Boyd (4-4) L: Jerry Koosman (10-7) | Sixth | 15 out |
| Saturday, September 3 |
| » Lost to White Sox (77-58), 9-6 | Fenway Park (30-37) | 65-71 | |
| » W: Richard Dotson (16-7) L: John Tudor (10-10) | Sixth | 16 out |
| Sunday, September 4 |
| » Defeated White Sox (77-59), 6-2 | Fenway Park (31-37) | 66-71 | |
| » W: Bruce Hurst (11-10) L: Britt Burns (8-9) | Sixth | 16 out |
| Monday, September 5 |
| » Defeated Orioles (80-54), 2-0 | Memorial Stadium (3-1) | 67-71 | Won 2 |
| » W: Bob Ojeda (8-7) L: Mike Boddicker (12-7) S: Bob Stanley (27) | Sixth | 15 out |
| Tuesday, September 6 |
| » Lost to Orioles (81-54), 8-1 | Memorial Stadium (3-2) | 67-72 | |
| » W: Jim Palmer (4-4) L: Dennis Eckersley (7-12) | Sixth | 16 out |
| » Major-league debuts: Jackie Gutierrez and Al Nipper (Red Sox) |
| Wednesday, September 7 |
| » Lost to Orioles (82-54), 5-2 | Memorial Stadium (3-3) | 67-73 | Lost 2 |
| » W: Mike Flanagan (10-3) L: Oil Can Boyd (4-5) S: Tippy Martinez (15) | Sixth | 17 out |
| Friday, September 9 |
| » Defeated Indians (63-78), 6-4 | Cleveland Stadium (3-1) | 68-73 | |
| » W: John Tudor (11-10) L: Neal Heaton (10-5) S: Bob Stanley (28) | Fifth | 16 out |
| Saturday, September 10 |
| » Lost to Indians (64-78), 8-6 | Cleveland Stadium (3-2) | 68-74 | |
| » W: Rich Barnes (1-0) L: Doug Bird (1-4) S: Bud Anderson (7) | Sixth | 17½ out |
| Sunday, September 11 |
| » Defeated Indians (64-79), 4-1 | Cleveland Stadium (4-2) | 69-74 | |
| » W: Bob Ojeda (9-7) L: Lary Sorensen (10-10) | Sixth | 17½ out |
| Tuesday, September 13 |
| » Lost to Orioles (86-55), 7-4 | Fenway Park (31-38) | 69-75 | |
| » W: Sammy Stewart (8-3) L: Bob Stanley (8-10) | Sixth | 19½ out |
| » Lost to Orioles (87-55), 7-1 | Fenway Park (31-39) | 69-76 | Lost 2 |
| » W: Bill Swaggerty (1-0) L: Al Nipper (0-1) | Sixth | 19½ out |
| Wednesday, September 14 |
| » Lost to Orioles (88-55), 5-0 | Fenway Park (31-40) | 69-77 | Lost 3 |
| » W: Dennis Martinez (7-14) L: John Tudor (11-11) S: Sammy Stewart (6) | Sixth | 20½ out |
| Thursday, September 15 |
| » Defeated Orioles (88-56), 7-1 | Fenway Park (32-40) | 70-77 | |
| » W: Bruce Hurst (12-10) L: Storm Davis (12-6) | Sixth | 19½ out |
| Friday, September 16 |
| » Defeated Tigers (84-63), 6-1 | Fenway Park (33-40) | 71-77 | Won 2 |
| » W: Bob Ojeda (10-7) L: Dan Petry (17-9) | Sixth | 19½ out |
| Saturday, September 17 |
| » Defeated Tigers (84-64), 3-2 | Fenway Park (34-40) | 72-77 | Won 3 |
| » W: Dennis Eckersley (8-12) L: Jack Morris (19-11) S: Bob Stanley (29) | Sixth | 19½ out |
| Sunday, September 18 |
| » Lost to Tigers (85-64), 9-6 | Fenway Park (34-41) | 72-78 | |
| » W: Milt Wilcox (10-10) L: Oil Can Boyd (4-6) S: Dave Gumpert (1) | Sixth | 20½ out |
| Monday, September 19 |
| » Defeated Yankees (83-66), 5-3 | Fenway Park (35-41) | 73-78 | |
| » W: John Tudor (12-11) L: Ron Guidry (19-9) S: Bob Stanley (30) | |
