| Tuesday, April 6 |
| » Lost to Braves (1-0), 1-0 | San Diego/Jack Murphy Stadium (0-1) | 0-1 | |
| » W: Rick Mahler (1-0) L: Juan Eichelberger (0-1) | Second | 1 out |
| Wednesday, April 7 |
| » Lost to Braves (2-0), 6-4 | San Diego/Jack Murphy Stadium (0-2) | 0-2 | Lost 2 |
| » W: Bob Walk (1-0) L: John Montefusco (0-1) S: Gene Garber (1) | Third | 2 out |
| » Major-league debuts: Floyd Chiffer (Padres) |
| Friday, April 9 |
| » Defeated Dodgers (2-1), 7-4 | Dodger Stadium (1-0) | 1-2 | |
| » W: Floyd Chiffer (1-0) L: Terry Forster (1-1) S: Gary Lucas (1) | Fourth | 2 out |
| Saturday, April 10 |
| » Lost to Dodgers (3-1), 6-0 | Dodger Stadium (1-1) | 1-3 | |
| » W: Fernando Valenzuela (1-0) L: Juan Eichelberger (0-2) | Fifth | 3 out |
| Tuesday, April 13 |
| » Lost to Giants (3-3), 3-2 | Candlestick Park (0-1) | 1-4 | Lost 2 |
| » W: Alan Fowlkes (1-0) L: John Montefusco (0-2) S: Greg Minton (1) | Sixth | 5 out |
| Wednesday, April 14 |
| » Defeated Giants (3-4), 3-2 | Candlestick Park (1-1) | 2-4 | |
| » W: Tim Lollar (1-0) L: Dan Schatzeder (0-2) S: Gary Lucas (2) | Fifth | 5 out |
| Thursday, April 15 |
| » Defeated Dodgers (4-4), 2-0 | San Diego/Jack Murphy Stadium (1-2) | 3-4 | Won 2 |
| » W: Juan Eichelberger (1-2) L: Fernando Valenzuela (1-1) S: Gary Lucas (3) | Fourth | 4½ out |
| Friday, April 16 |
| » Defeated Dodgers (4-5), 8-3 | San Diego/Jack Murphy Stadium (2-2) | 4-4 | Won 3 |
| » W: John Curtis (1-0) L: Jerry Reuss (0-1) | Second | 4½ out |
| Saturday, April 17 |
| » Defeated Dodgers (4-6), 4-3 | San Diego/Jack Murphy Stadium (3-2) | 5-4 | Won 4 |
| » W: Eric Show (1-0) L: Dave Goltz (0-1) S: Gary Lucas (4) | Second | 4½ out |
| Sunday, April 18 |
| » Defeated Dodgers (4-7), 9-3 | San Diego/Jack Murphy Stadium (4-2) | 6-4 | Won 5 |
| » W: Luis DeLeon (1-0) L: Dave Stewart (0-2) | Second | 4½ out |
| Monday, April 19 |
| » Defeated Giants (5-6), 13-6 | San Diego/Jack Murphy Stadium (5-2) | 7-4 | Won 6 |
| » W: Juan Eichelberger (2-2) L: Dan Schatzeder (0-3) | Second | 4 out |
| Tuesday, April 20 |
| » Defeated Giants (5-7), 8-4 | San Diego/Jack Murphy Stadium (6-2) | 8-4 | Won 7 |
| » W: John Curtis (2-0) L: Rich Gale (1-1) S: Danny Boone (1) | Second | 4 out |
| Wednesday, April 21 |
| » Defeated Giants (5-8), 7-6 | San Diego/Jack Murphy Stadium (7-2) | 9-4 | Won 8 |
| » W: John Montefusco (1-2) L: Al Holland (1-2) S: Gary Lucas (5) | Second | 4 out |
| Friday, April 23 |
| » Defeated Braves (13-2), 6-3 | Atlanta-Fulton County Stadium (1-0) | 10-4 | Won 9 |
| » W: Floyd Chiffer (2-0) L: Rick Camp (2-1) | Second | 2½ out |
| Saturday, April 24 |
| » Defeated Braves (13-3), 6-4 | Atlanta-Fulton County Stadium (2-0) | 11-4 | Won 10 |
| » W: Eric Show (2-0) L: Gene Garber (1-1) S: Luis DeLeon (1) | Second | 1½ out |
| Tuesday, April 27 |
| » Defeated Mets (9-8), 8-5 | San Diego/Jack Murphy Stadium (8-2) | 12-4 | Won 11 |
| » W: Eric Show (3-0) L: Jesse Orosco (0-3) | First | -- |
| Wednesday, April 28 |
| » Lost to Mets (10-8), 5-4 | San Diego/Jack Murphy Stadium (8-3) | 12-5 | |
| » W: Pete Falcone (2-0) L: Gary Lucas (0-1) | Second | 1 out |
| Thursday, April 29 |
| » Defeated Mets (10-9), 6-0 | San Diego/Jack Murphy Stadium (9-3) | 13-5 | |
| » W: Tim Lollar (2-0) L: Charlie Puleo (2-2) | Second | 1 out |
| Friday, April 30 |
| » Lost to Phillies (6-13), 3-1 | San Diego/Jack Murphy Stadium (9-4) | 13-6 | |
| » W: Steve Carlton (2-4) L: Juan Eichelberger (2-3) | Second | 2 out |
| Saturday, May 1 |
| » Defeated Phillies (6-14), 9-6 | San Diego/Jack Murphy Stadium (10-4) | 14-6 | |
| » W: Luis DeLeon (2-0) L: Larry Christenson (1-3) | Second | 1 out |
| Sunday, May 2 |
| » Lost to Phillies (7-14), 3-0 | San Diego/Jack Murphy Stadium (10-5) | 14-7 | |
| » W: Mike Krukow (2-2) L: John Curtis (2-1) | Second | 2 out |
| Monday, May 3 |
| » Lost to Expos (12-8), 8-2 | San Diego/Jack Murphy Stadium (10-6) | 14-8 | Lost 2 |
| » W: Bill Gullickson (2-1) L: John Montefusco (1-3) | Second | 3 out |
| Tuesday, May 4 |
| » Defeated Expos (12-9), 7-3 | San Diego/Jack Murphy Stadium (11-6) | 15-8 | |
| » W: Tim Lollar (3-0) L: Ray Burris (0-5) S: Floyd Chiffer (1) | Second | 2 out |
| Thursday, May 6 |
| » Lost to Phillies (10-14), 12-7 | Veteran's Stadium (0-1) | 15-9 | |
| » W: Larry Christenson (2-3) L: Juan Eichelberger (2-4) | Second | 2 out |
| Friday, May 7 |
| » Lost to Phillies (11-14), 5-2 | Veteran's Stadium (0-2) | 15-10 | Lost 2 |
| » W: Sparky Lyle (1-0) L: Gary Lucas (0-2) | Second | 3 out |
| Saturday, May 8 |
| » Lost to Phillies (12-14), 5-1 | Veteran's Stadium (0-3) | 15-11 | Lost 3 |
| » W: Dick Ruthven (1-3) L: John Montefusco (1-4) | Second | 3 out |
| Sunday, May 9 |
| » Defeated Phillies (12-15), 6-0 | Veteran's Stadium (1-3) | 16-11 | |
| » W: Tim Lollar (4-0) L: Steve Carlton (3-5) | Second | 3 out |
| Monday, May 10 |
| » Lost to Mets (15-15), 3-2 | Shea Stadium (0-1) | 16-12 | |
| » W: Randy Jones (4-1) L: Gary Lucas (0-3) | Second | 3½ out |
| Tuesday, May 11 |
| » Lost to Mets (16-15), 6-0 | Shea Stadium (0-2) | 16-13 | Lost 2 |
| » W: Charlie Puleo (4-2) L: Juan Eichelberger (2-5) | Second | 3½ out |
| Thursday, May 13 |
| » Lost to Expos (14-15), 6-5 | Stade Olympique (0-1) | 16-14 | Lost 3 |
| » W: Woodie Fryman (2-0) L: Luis DeLeon (2-1) | Second | 4 out |
| Friday, May 14 |
| » Lost to Expos (15-15), 8-7 | Stade Olympique (0-2) | 16-15 | Lost 4 |
| » W: Tom Gorman (1-0) L: Eric Show (3-1) S: Jeff Reardon (6) | Second | 5 out |
| Saturday, May 15 |
| » Defeated Expos (15-16), 6-2 | Stade Olympique (1-2) | 17-15 | |
| » W: Chris Welsh (1-0) L: Charlie Lea (1-2) | Second | 4 out |
| Sunday, May 16 |
| » Defeated Expos (15-17), 8-2 | Stade Olympique (2-2) | 18-15 | Won 2 |
| » W: Juan Eichelberger (3-5) L: Woodie Fryman (2-1) | Second | 4 out |
| Tuesday, May 18 |
| » Lost to Cardinals (23-14), 2-0 | San Diego/Jack Murphy Stadium (11-7) | 18-16 | |
| » W: Bob Forsch (5-0) L: John Curtis (2-2) | Second | 4½ out |
| Wednesday, May 19 |
| » Defeated Cardinals (23-15), 5-4 | San Diego/Jack Murphy Stadium (12-7) | 19-16 | |
| » W: Danny Boone (1-0) L: Bruce Sutter (2-1) | Second | 4½ out |
| Thursday, May 20 |
| » Lost to Cardinals (24-15), 6-3 | San Diego/Jack Murphy Stadium (12-8) | 19-17 | |
| » W: Dave LaPoint (2-0) L: Chris Welsh (1-1) | Second | 5 out |
| Friday, May 21 |
| » Defeated Pirates (15-21), 7-5 | San Diego/Jack Murphy Stadium (13-8) | 20-17 | |
| » W: John Montefusco (2-4) L: Eddie Solomon (1-5) S: Gary Lucas (6) | Second | 5 out |
| Saturday, May 22 |
| » Defeated Pirates (15-22), 12-3 | San Diego/Jack Murphy Stadium (14-8) | 21-17 | Won 2 |
| » W: Juan Eichelberger (4-5) L: Paul Moskau (0-3) | Second | 4 out |
| Sunday, May 23 |
| » Lost to Pirates (16-22), 4-2 | San Diego/Jack Murphy Stadium (14-9) | 21-18 | |
| » W: John Candelaria (1-2) L: John Curtis (2-3) S: Rod Scurry (3) | Second | 4 out |
| Monday, May 24 |
| » Defeated Cubs (18-25), 8-2 | San Diego/Jack Murphy Stadium (15-9) | 22-18 | |
| » W: Tim Lollar (5-0) L: Dickie Noles (5-5) | Second | 3 out |
| Tuesday, May 25 |
| » Defeated Cubs (18-26), 2-1 | San Diego/Jack Murphy Stadium (16-9) | 23-18 | Won 2 |
| » W: Chris Welsh (2-1) L: Fergie Jenkins (3-5) S: Floyd Chiffer (2) | Second | 3 out |
| Wednesday, May 26 |
| » Lost to Cubs (19-26), 5-3 | San Diego/Jack Murphy Stadium (16-10) | 23-19 | |
| » W: Willie Hernandez (2-2) L: Luis DeLeon (2-2) S: Bill Campbell (4) | Second | 3 out |
| Friday, May 28 |
| » Lost to Cardinals (29-17), 5-2 | Busch Stadium II (0-1) | 23-20 | Lost 2 |
| » W: Bob Forsch (6-1) L: Juan Eichelberger (4-6) S: Bruce Sutter (14) | Second | 3½ out |
| Saturday, May 29 |
| » Defeated Cardinals (29-18), 4-2 | Busch Stadium II (1-1) | 24-20 | |
| » W: John Curtis (3-3) L: Joaquin Andujar (4-4) S: Eric Show (1) | Second | 2½ out |
| Sunday, May 30 |
| » Lost to Cardinals (30-18), 6-5 | Busch Stadium II (1-2) | 24-21 | |
| » W: Bruce Sutter (3-1) L: Gary Lucas (0-4) | Second | 2½ out |
| Monday, May 31 |
| » Defeated Cubs (21-28), 9-7 | Wrigley Field (1-0) | 25-21 | |
| » W: Chris Welsh (3-1) L: Doug Bird (3-5) S: Luis DeLeon (2) | Second | 1½ out |
| Tuesday, June 1 |
| » Defeated Cubs (21-29), 9-1 | Wrigley Field (2-0) | 26-21 | Won 2 |
| » W: John Montefusco (3-4) L: Randy Martz (4-4) S: Eric Show (2) | Second | 1½ out |
| Wednesday, June 2 |
| » Defeated Cubs (21-30), 3-1 | Wrigley Field (3-0) | 27-21 | Won 3 |
| » W: Juan Eichelberger (5-6) L: Dickie Noles (5-6) | Second | 1½ out |
| Friday, June 4 |
| » Defeated Pirates (21-28), 5-4 | Three Rivers Stadium (1-0) | 28-21 | Won 4 |
| » W: John Curtis (4-3) L: Rick Rhoden (2-6) S: Gary Lucas (7) | Second | 1 out |
| Sunday, June 6 |
| » Lost to Pirates (22-28), 2-1 | Three Rivers Stadium (1-1) | 28-22 | |
| » W: Kent Tekulve (3-1) L: Tim Lollar (5-1) | Second | 1½ out |
| Monday, June 7 |
| » Defeated Reds (22-31), 6-5 | San Diego/Jack Murphy Stadium (17-10) | 29-22 | |
| » W: Chris Welsh (4-1) L: Greg Harris (2-1) S: Luis DeLeon (3) | Second | 1½ out |
| Tuesday, June 8 |
| » Defeated Reds (22-32), 4-1 | San Diego/Jack Murphy Stadium (18-10) | 30-22 | Won 2 |
| » W: John Montefusco (4-4) L: Bruce Berenyi (4-6) S: Luis DeLeon (4) | Second | 1½ out |
| Wednesday, June 9 |
| » Lost to Reds (23-32), 4-3 | San Diego/Jack Murphy Stadium (18-11) | 30-23 | |
| » W: Tom Seaver (3-6) L: Juan Eichelberger (5-7) S: Tom Hume (10) | Second | 2½ out |
| Thursday, June 10 |
| » Defeated Astros (25-31), 5-0 | San Diego/Jack Murphy Stadium (19-11) | 31-23 | |
| » W: John Curtis (5-3) L: Bob Knepper (2-7) | Second | 2 out |
| Friday, June 11 |
| » Defeated Astros (25-32), 6-2 | San Diego/Jack Murphy Stadium (20-11) | 32-23 | Won 2 |
| » W: Tim Lollar (6-1) L: Don Sutton (7-3) | Second | 2 out |
| Saturday, June 12 |
| » Defeated Astros (25-33), 4-0 | San Diego/Jack Murphy Stadium (21-11) | 33-23 | Won 3 |
| » W: Chris Welsh (5-1) L: Vern Ruhle (4-4) | Second | 2 out |
| Sunday, June 13 |
| » Defeated Astros (25-34), 5-4 | San Diego/Jack Murphy Stadium (22-11) | 34-23 | Won 4 |
| » W: John Montefusco (5-4) L: Nolan Ryan (5-8) S: Gary Lucas (8) | Second | 1½ out |
| Monday, June 14 |
| » Lost to Dodgers (30-32), 4-3 | San Diego/Jack Murphy Stadium (22-12) | 34-24 | |
| » W: Steve Howe (5-1) L: Eric Show (3-2) | Second | 1½ out |
| Tuesday, June 15 |
| » Lost to Dodgers (31-32), 3-0 | San Diego/Jack Murphy Stadium (22-13) | 34-25 | Lost 2 |
| » W: Jerry Reuss (7-5) L: John Curtis (5-4) | Second | 2½ out |
| » Major-league debuts: Dave Dravecky (Padres) |
| Wednesday, June 16 |
| » Lost to Dodgers (32-32), 6-0 | San Diego/Jack Murphy Stadium (22-14) | 34-26 | Lost 3 |
| » W: Bob Welch (7-4) L: Tim Lollar (6-2) | Second | 3½ out |
| Friday, June 18 |
| » Lost to Astros (27-36), 7-2 | Astrodome (0-1) | 34-27 | Lost 4 |
| » W: Nolan Ryan (6-8) L: Chris Welsh (5-2) | Second | 4½ out |
| Saturday, June 19 |
| » Defeated Astros (27-37), 7-1 | Astrodome (1-1) | 35-27 | |
| » W: John Montefusco (6-4) L: Joe Niekro (6-5) S: Gary Lucas (9) | Second | 3½ out |
| Sunday, June 20 |
| » Lost to Astros (28-37), 8-4 | Astrodome (1-2) | 35-28 | |
| » W: Mike LaCoss (2-1) L: Juan Eichelberger (5-8) | Second | 3½ out |
| Monday, June 21 |
| » Defeated Astros (28-38), 7-4 | Astrodome (2-2) | 36-28 | |
| » W: Eric Show (4-2) L: Mike LaCoss (2-2) | Second | 3½ out |
| Tuesday, June 22 |
| » Lost to Reds (29-38), 7-5 | Riverfront Stadium (0-1) | 36-29 | |
| » W: Joe Price (2-2) L: Gary Lucas (0-5) S: Tom Hume (15) | Second | 3½ out |
| Wednesday, June 23 |
| » Lost to Reds (30-38), 5-4 | Riverfront Stadium (0-2) | 36-30 | Lost 2 |
| » W: Tom Hume (1-2) L: Eric Show (4-3) | Second | 4½ out |
| Thursday, June 24 |
| » Defeated Reds (30-39), 7-6 | Riverfront Stadium (1-2) | 37-30 | |
| » W: Eric Show (5-3) L: Bob Shirley (2-4) | Second | 3½ out |
| Friday, June 25 |
| » Defeated Giants (32-40), 3-2 | Candlestick Park (2-1) | 38-30 | Won 2 |
| » W: Juan Eichelberger (6-8) L: Bill Laskey (6-5) S: Gary Lucas (10) | Second | 3½ out |
| Saturday, June 26 |
| » Defeated Giants (32-41), 7-6 | Candlestick Park (3-1) | 39-30 | Won 3 |
| » W: Eric Show (6-3) L: Gary Lavelle (4-3) | Second | 2½ out |
| Sunday, June 27 |
| » Defeated Giants (32-42), 4-2 | Candlestick Park (4-1) | 40-30 | Won 4 |
| » W: Tim Lollar (7-2) L: Rich Gale (2-8) S: Floyd Chiffer (3) | Second | 2½ out |
| Monday, June 28 |
| » Lost to Dodgers (40-35), 6-4 | Dodger Stadium (1-2) | 40-31 | |
| » W: Fernando Valenzuela (10-6) L: Chris Welsh (5-3) S: Steve Howe (7) | Second | 2½ out |
| Tuesday, June 29 |
| » Defeated Dodgers (40-36), 7-5 | Dodger Stadium (2-2) | 41-31 | |
| » W: Luis DeLeon (3-2) L: Steve Shirley (0-1) | Second | 2½ out |
| Wednesday, June 30 |
| » Lost to Dodgers (41-36), 5-1 | Dodger Stadium (2-3) | 41-32 | |
| » W: Bob Welch (8-5) L: Juan Eichelberger (6-9) | Second | 3 out |
| » Defeated Dodgers (41-37), 6-4 | Dodger Stadium (3-3) | 42-32 | |
| » W: Eric Show (7-3) L: Terry Forster (3-5) S: Luis DeLeon (5) | Second | 3 out |
| Friday, July 2 |
| » Lost to Giants (36-42), 8-4 | San Diego/Jack Murphy Stadium (22-15) | 42-33 | |
| » W: Al Holland (3-3) L: Dave Dravecky (0-1) | Second | 3½ out |
| » Defeated Giants (36-43), 3-2 | San Diego/Jack Murphy Stadium (23-15) | 43-33 | |
| » W: Tim Lollar (8-2) L: Gary Lavelle (4-4) S: Gary Lucas (11) | Second | 3½ out |
| Saturday, July 3 |
| » Lost to Giants (37-43), 4-3 | San Diego/Jack Murphy Stadium (23-16) | 43-34 | |
| » W: Greg Minton (5-4) L: Floyd Chiffer (2-1) | Second | 4½ out |
| Sunday, July 4 |
| » Defeated Giants (37-44), 4-3 | San Diego/Jack Murphy Stadium (24-16) | 44-34 | |
| » W: Dave Dravecky (1-1) L: Atlee Hammaker (5-5) | Second | 4½ out |
| Monday, July 5 |
| » Defeated Expos (41-38), 8-6 | Stade Olympique (3-2) | 45-34 | Won 2 |
| » W: Floyd Chiffer (3-1) L: Scott Sanderson (6-7) S: Gary Lucas (12) | Second | 4½ out |
| Tuesday, July 6 |
| » Defeated Expos (41-39), 5-1 | Stade Olympique (4-2) | 46-34 | Won 3 |
| » W: John Curtis (6-4) L: Ray Burris (3-11) S: Luis DeLeon (6) | Second | 3½ out |
| Wednesday, July 7 |
| » Defeated Phillies (45-36), 5-3 | Veteran's Stadium (2-3) | 47-34 | Won 4 |
| » W: Tim Lollar (9-2) L: Marty Bystrom (2-2) S: Luis DeLeon (7) | Second | 3½ out |
| Thursday, July 8 |
| » Defeated Phillies (45-37), 5-3 | Veteran's Stadium (3-3) | 48-34 | Won 5 |
| » W: John Montefusco (7-4) L: Mike Krukow (8-6) S: Eric Show (3) | Second | 2½ out |
| Friday, July 9 |
| » Defeated Mets (38-46), 5-3 | Shea Stadium (1-2) | 49-34 | Won 6 |
| » W: Floyd Chiffer (4-1) L: Charlie Puleo (6-6) S: Luis DeLeon (8) | Second | 3 out |
| » Lost to Mets (39-46), 6-3 | Shea Stadium (1-3) | 49-35 | |
| » W: Pat Zachry (5-3) L: Gary Lucas (0-6) S: Neil Allen (17) | Second | 3 out |
| Saturday, July 10 |
| » Lost to Mets (40-46), 9-7 | Shea Stadium (1-4) | 49-36 | Lost 2 |
| » W: Pete Falcone (5-6) L: John Curtis (6-5) S: Terry Leach (2) | Second | 3 out |
| Sunday, July 11 |
| » Defeated Mets (40-47), 6-2 | Shea Stadium (2-4) | 50-36 | |
| » W: Tim Lollar (10-2) L: Mike Scott (6-7) | Second | 2 out |
| Thursday, July 15 |
| » Lost to Expos (44-42), 6-2 | San Diego/Jack Murphy Stadium (24-17) | 50-37 | |
| » W: Charlie Lea (7-5) L: John Montefusco (7-5) | Second | 3 out |
| Friday, July 16 |
| » Lost to Expos (45-42), 4-3 | San Diego/Jack Murphy Stadium (24-18) | 50-38 | Lost 2 |
| » W: Steve Rogers (11-4) L: Tim Lollar (10-3) S: Woodie Fryman (6) | Second | 3 out |
| Saturday, July 17 |
| » Lost to Expos (46-42), 4-1 | San Diego/Jack Murphy Stadium (24-19) | 50-39 | Lost 3 |
| » W: Bill Gullickson (7-8) L: Andy Hawkins (0-1) | Second | 4 out |
| » Major-league debuts: Andy Hawkins (Padres) |
| Sunday, July 18 |
| » Lost to Expos (47-42), 9-2 | San Diego/Jack Murphy Stadium (24-20) | 50-40 | Lost 4 |
| » W: David Palmer (5-2) L: Chris Welsh (5-4) S: Ray Burris (2) | Second | 5 out |
| Monday, July 19 |
| » Lost to Phillies (51-39), 7-6 | San Diego/Jack Murphy Stadium (24-21) | 50-41 | Lost 5 |
| » W: Sid Monge (4-0) L: John Curtis (6-6) S: Ron Reed (2) | Second | 6 out |
| » Major-league debuts: Tony Gwynn (Padres) |
| Tuesday, July 20 |
| » Defeated Phillies (51-40), 2-0 | San Diego/Jack Murphy Stadium (25-21) | 51-41 | |
| » W: John Montefusco (8-5) L: Steve Carlton (12-8) S: Luis DeLeon (9) | Second | 6 out |
| Wednesday, July 21 |
| » Lost to Phillies (52-40), 7-1 | San Diego/Jack Murphy Stadium (25-22) | 51-42 | |
| » W: Dick Ruthven (8-7) L: Tim Lollar (10-4) | Second | 6 out |
| Friday, July 23 |
| » Defeated Mets (43-51), 11-4 | San Diego/Jack Murphy Stadium (26-22) | 52-42 | |
| » W: Andy Hawkins (1-1) L: Brent Gaff (0-2) | Second | 5 out |
| Former Padre Roberto Pena dies in Santiago, D.R. at the age of 46. |
| Saturday, July 24 |
| » Lost to Mets (44-51), 4-3 | San Diego/Jack Murphy Stadium (26-23) | 52-43 | |
| » W: Neil Allen (3-5) L: Luis DeLeon (3-3) S: Pete Falcone (1) | Second | 6 out |
| Sunday, July 25 |
| » Defeated Mets (44-52), 3-2 | San Diego/Jack Murphy Stadium (27-23) | 53-43 | |
| » W: Luis DeLeon (4-3) L: Neil Allen (3-6) | Second | 5 out |
| Tuesday, July 27 |
| » Lost to Braves (58-37), 9-2 | Atlanta-Fulton County Stadium (2-1) | 53-44 | |
| » W: Bob Walk (9-7) L: Tim Lollar (10-5) | Second | 7 out |
| » Lost to Braves (59-37), 8-6 | Atlanta-Fulton County Stadium (2-2) | 53-45 | Lost 2 |
| » W: Steve Bedrosian (5-1) L: Gary Lucas (0-7) | Second | 7 out |
| Wednesday, July 28 |
| » Lost to Braves (60-37), 8-6 | Atlanta-Fulton County Stadium (2-3) | 53-46 | Lost 3 |
| » W: Phil Niekro (10-3) L: Andy Hawkins (1-2) S: Gene Garber (19) | Second | 8 out |
| Thursday, July 29 |
| » Lost to Braves (61-37), 6-2 | Atlanta-Fulton County Stadium (2-4) | 53-47 | Lost 4 |
| » W: Rick Camp (8-4) L: Chris Welsh (5-5) S: Carlos Diaz (1) | Second | 9 out |
| Friday, July 30 |
| » Lost to Reds (38-63), 4-2 | Riverfront Stadium (1-3) | 53-48 | Lost 5 |
| » W: Bruce Berenyi (8-10) L: John Montefusco (8-6) | Second | 8½ out |
| Saturday, July 31 |
| » Defeated Reds (38-64), 5-4 | Riverfront Stadium (2-3) | 54-48 | |
| » W: Tim Lollar (11-5) L: Tom Seaver (4-11) S: Dave Dravecky (1) | Second | 7 out |
| » Defeated Reds (38-65), 6-2 | Riverfront Stadium (3-3) | 55-48 | Won 2 |
| » W: Eric Show (8-3) L: Bob Shirley (3-8) S: Gary Lucas (13) | Second | 7 out |
| » Major-league debuts: Jody Lansford (Padres) |
| Sunday, August 1 |
| » Defeated Reds (38-66), 8-6 | Riverfront Stadium (4-3) | 56-48 | Won 3 |
| » W: John Curtis (7-6) L: Charlie Leibrandt (3-7) S: Luis DeLeon (10) | Second | 6 out |
| Monday, August 2 |
| » Lost to Astros (47-56), 6-4 | Astrodome (2-3) | 56-49 | |
| » W: Joe Niekro (11-7) L: Gary Lucas (0-8) S: Dave Smith (8) | Second | 7 out |
| Tuesday, August 3 |
| » Lost to Astros (48-56), 7-6 | Astrodome (2-4) | 56-50 | Lost 2 |
| » W: Randy Moffitt (2-3) L: Luis DeLeon (4-4) | Third | 7 out |
| Wednesday, August 4 |
| » Defeated Astros (48-57), 5-2 | Astrodome (3-4) | 57-50 | |
| » W: John Montefusco (9-6) L: Don Sutton (10-8) | Third | 6 out |
| Thursday, August 5 |
| » Lost to Reds (40-68), 4-2 | San Diego/Jack Murphy Stadium (27-24) | 57-51 | |
| » W: Tom Seaver (5-11) L: Tim Lollar (11-6) S: Brad Lesley (1) | Third | 6 out |
| Friday, August 6 |
| » Defeated Reds (40-69), 2-0 | San Diego/Jack Murphy Stadium (28-24) | 58-51 | |
| » W: Eric Show (9-3) L: Bob Shirley (3-9) | Third | 5 out |
| Future Padre Justin Germano is born in Pasadena, CA. |
| Saturday, August 7 |
| » Defeated Reds (40-70), 4-1 | San Diego/Jack Murphy Stadium (29-24) | 59-51 | Won 2 |
| » W: Andy Hawkins (2-2) L: Mario Soto (9-8) S: Gary Lucas (14) | Third | 4 out |
| Sunday, August 8 |
| » Defeated Reds (40-71), 3-1 | San Diego/Jack Murphy Stadium (30-24) | 60-51 | Won 3 |
| » W: Dave Dravecky (2-1) L: Frank Pastore (5-9) S: Gary Lucas (15) | Third | 3 out |
| Monday, August 9 |
| » Lost to Astros (49-62), 4-3 | San Diego/Jack Murphy Stadium (30-25) | 60-52 | |
| » W: Don Sutton (11-8) L: John Montefusco (9-7) S: Dave Smith (9) | Third | 3 out |
| Tuesday, August 10 |
| » Lost to Astros (50-62), 4-1 | San Diego/Jack Murphy Stadium (30-26) | 60-53 | Lost 2 |
| » W: Vern Ruhle (6-8) L: Tim Lollar (11-7) S: Randy Moffitt (2) | Third | 3½ out |
| Wednesday, August 11 |
| » Lost to Astros (51-62), 3-0 | San Diego/Jack Murphy Stadium (30-27) | 60-54 | Lost 3 |
| » W: Nolan Ryan (12-9) L: Eric Show (9-4) | Third | 3½ out |
| Thursday, August 12 |
| » Defeated Braves (62-51), 8-2 | San Diego/Jack Murphy Stadium (31-27) | 61-54 | |
| » W: Chris Welsh (6-5) L: Bob Walk (10-8) | Third | 3½ out |
| Friday, August 13 |
| » Defeated Braves (62-52), 7-4 | San Diego/Jack Murphy Stadium (32-27) | 62-54 | Won 2 |
| » W: Dave Dravecky (3-1) L: Rick Camp (8-6) | Third | 3½ out |
| Saturday, August 14 |
| » Lost to Braves (63-52), 6-5 | San Diego/Jack Murphy Stadium (32-28) | 62-55 | |
| » W: Donnie Moore (1-0) L: Juan Eichelberger (6-10) S: Gene Garber (20) | Third | 3½ out |
| Sunday, August 15 |
| » Defeated Braves (63-53), 6-5 | San Diego/Jack Murphy Stadium (33-28) | 63-55 | |
| » W: Luis DeLeon (5-4) L: Steve Bedrosian (5-6) | Third | 2½ out |
| Tuesday, August 17 |
| » Lost to Cardinals (68-50), 3-2 | Busch Stadium II (1-3) | 63-56 | |
| » W: Bruce Sutter (8-5) L: Gary Lucas (0-9) | Third | 3 out |
| Wednesday, August 18 |
| » Lost to Cardinals (69-50), 2-1 | Busch Stadium II (1-4) | 63-57 | Lost 2 |
| » W: Bob Forsch (12-7) L: Andy Hawkins (2-3) S: Bruce Sutter (25) | Third | 4½ out |
| Thursday, August 19 |
| » Defeated Cardinals (69-51), 4-3 | Busch Stadium II (2-4) | 64-57 | |
| » W: Dave Dravecky (4-1) L: John Stuper (5-3) S: Luis DeLeon (11) | Third | 3½ out |
| Friday, August 20 |
| » Lost to Cubs (53-71), 3-2 | Wrigley Field (3-1) | 64-58 | |
| » W: Randy Martz (7-8) L: John Montefusco (9-8) S: Willie Hernandez (9) | Third | 4½ out |
| Saturday, August 21 |
| » Defeated Cubs (53-72), 2-0 | Wrigley Field (4-1) | 65-58 | |
| » W: Tim Lollar (12-7) L: Allen Ripley (4-7) S: Luis DeLeon (12) | Third | 3½ out |
| Sunday, August 22 |
| » Lost to Cubs (54-72), 8-7 | Wrigley Field (4-2) | 65-59 | |
| » W: Dick Tidrow (6-2) L: Gary Lucas (0-10) S: Lee Smith (9) | Third | 3½ out |
| Monday, August 23 |
| » Lost to Pirates (65-59), 8-6 | Three Rivers Stadium (1-2) | 65-60 | Lost 2 |
| » W: John Candelaria (11-5) L: Andy Hawkins (2-4) S: Rod Scurry (10) | Third | 3 out |
| » Defeated Pirates (65-60), 5-3 | Three Rivers Stadium (2-2) | 66-60 | |
| » W: Chris Welsh (7-5) L: Ross Baumgarten (0-5) S: Floyd Chiffer (4) | Third | 3 out |
| Tuesday, August 24 |
| » Lost to Pirates (66-60), 6-5 | Three Rivers Stadium (2-3) | 66-61 | |
| » W: Kent Tekulve (9-6) L: Juan Eichelberger (6-11) | Third | 4 out |
| Wednesday, August 25 |
| » Lost to Pirates (67-60), 7-6 | Three Rivers Stadium (2-4) | 66-62 | Lost 2 |
| » W: Kent Tekulve (10-6) L: Floyd Chiffer (4-2) | Third | 5 out |
| Friday, August 27 |
| » Lost to Cardinals (73-54), 2-1 | San Diego/Jack Murphy Stadium (33-29) | 66-63 | Lost 3 |
| » W: Joaquin Andujar (10-10) L: Tim Lollar (12-8) S: Bruce Sutter (28) | Third | 6 out |
| Sunday, August 29 |
| » Defeated Cardinals (73-55), 9-4 | San Diego/Jack Murphy Stadium (34-29) | 67-63 | |
| » W: John Curtis (8-6) L: Bob Forsch (13-8) | Third | 6 out |
| » Lost to Cardinals (74-55), 5-3 | San Diego/Jack Murphy Stadium (34-30) | 67-64 | |
| » W: Doug Bair (4-3) L: Andy Hawkins (2-5) S: Bruce Sutter (29) | Third | 6 out |
| Monday, August 30 |
| » Defeated Pirates (69-62), 2-1 | San Diego/Jack Murphy Stadium (35-30) | 68-64 | |
| » W: Luis DeLeon (6-4) L: Kent Tekulve (10-7) | Third | 5½ out |
| Tuesday, August 31 |
| » Lost to Pirates (70-62), 7-1 | San Diego/Jack Murphy Stadium (35-31) | 68-65 | |
| » W: Manny Sarmiento (6-3) L: John Montefusco (9-9) | Third | 6½ out |
| Wednesday, September 1 |
| » Defeated Pirates (70-63), 4-1 | San Diego/Jack Murphy Stadium (36-31) | 69-65 | |
| » W: Juan Eichelberger (7-11) L: Rick Rhoden (8-12) | Third | 6½ out |
| Friday, September 3 |
| » Defeated Cubs (59-76), 3-0 | San Diego/Jack Murphy Stadium (37-31) | 70-65 | Won 2 |
| » W: Eric Show (10-4) L: Dickie Noles (8-11) | Third | 6½ out |
| Saturday, September 4 |
| » Defeated Cubs (59-77), 4-1 | San Diego/Jack Murphy Stadium (38-31) | 71-65 | Won 3 |
| » W: Tim Lollar (13-8) L: Fergie Jenkins (10-14) | Third | 5½ out |
| Sunday, September 5 |
| » Lost to Cubs (60-77), 5-1 | San Diego/Jack Murphy Stadium (38-32) | 71-66 | |
| » W: Randy Martz (9-8) L: Dave Dravecky (4-2) | Third | 5½ out |
| Monday, September 6 |
| » Defeated Astros (63-74), 4-2 | Astrodome (4-4) | 72-66 | |
| » W: Chris Welsh (8-5) L: Vern Ruhle (7-12) | Third | 4½ out |
| » Major-league debuts: Bill Doran (Astros) |
| Tuesday, September 7 |
| » Lost to Astros (64-74), 4-3 | Astrodome (4-5) | 72-67 | |
| » W: Frank DiPino (1-0) L: Juan Eichelberger (7-12) S: Danny Boone (2) | Third | 5 out |
| Wednesday, September 8 |
| » Defeated Reds (52-87), 9-4 | Riverfront Stadium (5-3) | 73-67 | |
| » W: Luis DeLeon (7-4) L: Brad Lesley (0-1) | Third | 4½ out |
| Thursday, September 9 |
| » Defeated Reds (52-88), 4-1 | Riverfront Stadium (6-3) | 74-67 | Won 2 |
| » W: Tim Lollar (14-8) L: Bruce Berenyi (8-16) S: Luis DeLeon (13) | Third | 4½ out |
| Friday, September 10 |
| » Lost to Giants (73-68), 5-1 | San Diego/Jack Murphy Stadium (38-33) | 74-68 | |
| » W: Fred Breining (9-4) L: Dave Dravecky (4-3) | Third | 5½ out |
| Saturday, September 11 |
| » Lost to Giants (74-68), 8-3 | San Diego/Jack Murphy Stadium (38-34) | 74-69 | Lost 2 |
| » W: Bill Laskey (13-10) L: Chris Welsh (8-6) S: Al Holland (2) | Fourth | 5½ out |
| Monday, September 13 |
| » Lost to Dodgers (81-64), 4-3 | Dodger Stadium (3-4) | 74-70 | Lost 3 |
| » W: Jerry Reuss (16-10) L: Chris Welsh (8-7) | Fourth | 6½ out |
| Tuesday, September 14 |
| » Lost to Dodgers (82-64), 1-0 | Dodger Stadium (3-5) | 74-71 | Lost 4 |
| » W: Fernando Valenzuela (18-12) L: Eric Show (10-5) | Fourth | 7½ out |
| Wednesday, September 15 |
| » Lost to Dodgers (83-64), 5-0 | Dodger Stadium (3-6) | 74-72 | Lost 5 |
| » W: Burt Hooton (3-5) L: John Montefusco (9-10) | Fourth | 8½ out |
| Thursday, September 16 |
| » Lost to Giants (77-69), 9-3 | Candlestick Park (4-2) | 74-73 | Lost 6 |
| » W: Fred Breining (10-4) L: Tim Lollar (14-9) S: Greg Minton (28) | Fourth | 9 out |
| Friday, September 17 |
| » Defeated Giants (77-70), 4-2 | Candlestick Park (5-2) | 75-73 | |
| » W: Dave Dravecky (5-3) L: Bill Laskey (13-11) S: Gary Lucas (16) | Fourth | 9 out |
| Saturday, September 18 |
| » Lost to Giants (78-70), 4-1 | Candlestick Park (5-3) | 75-74 | |
| » W: Rich Gale (7-14) L: Juan Eichelberger (7-13) S: Gary Lavelle (7) | Fourth | 9 out |
| Sunday, September 19 |
| » Lost to Giants (79-70), 4-3 | Candlestick Park (5-4) | 75-75 | Lost 2 |
| » W: Al Holland (6-3) L: Luis DeLeon (7-5) | Fourth | 10 out |
| Tuesday, September 21 |
| » Defeated Dodgers (85-66), 3-0 | San Diego/Jack Murphy Stadium (39-34) | 76-75 | |
| » W: John Montefusco (10-10) L: Burt Hooton (3-6) S: Luis DeLeon (14) | Fourth | 9 out |
| Wednesday, September 22 |
| » Defeated Dodgers (85-67), 2-1 | San Diego/Jack Murphy Stadium (40-34) | 77-75 | Won 2 |
| » W: Luis DeLeon (8-5) L: Tom Niedenfuer (3-3) | Fourth | 8 out |
| Friday, September 24 |
| » Lost to Braves (83-70), 11-6 | Atlanta-Fulton County Stadium (2-5) | 77-76 | |
| » W: Ken Dayley (5-6) L: Mike Griffin (0-1) S: Steve Bedrosian (11) | Fourth | 8 out |
| Saturday, September 25 |
| » Lost to Braves (84-70), 12-6 | Atlanta-Fulton County Stadium (2-6) | 77-77 | Lost 2 |
| » W: Donnie Moore (3-1) L: Juan Eichelberger (7-14) S: Gene Garber (29) | Fourth | 8 out |
| » Major-league debuts: Ron Tingley (Padres) |
| Sunday, September 26 |
| » Defeated Braves (84-71), 3-2 | Atlanta-Fulton County Stadium (3-6) | 78-77 | |
| » W: Gary Lucas (1-10) L: Rick Camp (11-11) | Third | 7 out |
| Monday, September 27 |
| » Lost to Astros (75-81), 7-3 | San Diego/Jack Murphy Stadium (40-35) | 78-78 | |
| » W: Vern Ruhle (9-13) L: Chris Welsh (8-8) | Third | 7 out |
| Tuesday, September 28 |
| » Defeated Astros (75-82), 3-0 | San Diego/Jack Murphy Stadium (41-35) | 79-78 | |
| » W: Tim Lollar (15-9) L: Bob Knepper (5-15) S: Luis DeLeon (15) | Fourth | 7 out |
| Wednesday, September 29 |
| » Defeated Reds (59-99), 3-2 | San Diego/Jack Murphy Stadium (42-35) | 80-78 | Won 2 |
| » W: Luis DeLeon (9-5) L: Brad Lesley (0-2) | Third | 7 out |
| Thursday, September 30 |
| » Lost to Reds (60-99), 6-4 | San Diego/Jack Murphy Stadium (42-36) | 80-79 | |
| » W: Charlie Leibrandt (5-7) L: Floyd Chiffer (4-3) S: Ben Hayes (2) | Third | 7 out |
| Friday, October 1 |
| » Lost to Braves (88-72), 4-0 | San Diego/Jack Murphy Stadium (42-37) | 80-80 | Lost 2 |
| » W: Phil Niekro (17-4) L: Eric Show (10-6) | Fourth | 8 out |
| Saturday, October 2 |
| » Lost to Braves (89-72), 4-2 | San Diego/Jack Murphy Stadium (42-38) | 80-81 | Lost 3 |
| » W: Pascual Perez (4-4) L: John Montefusco (10-11) S: Gene Garber (30) | Fourth | 9 out |
| Sunday, October 3 |
| » Defeated Braves (89-73), 5-1 | San Diego/Jack Murphy Stadium (43-38) | 81-81 | |
| » W: Tim Lollar (16-9) L: Rick Camp (11-13) S: Dave Dravecky (2) | Fourth | 8 out |
Game information provided by Retrosheet (www.retrosheet.org) |