| Wednesday, January 6 |
| Former Indian Wally Post dies in St.Henry, OH at the age of 53. |
| Friday, April 9 |
| » Major-league debuts: Jim Gott (Blue Jays) Kevin Bass and Doug Jones (Brewers) |
| Saturday, April 10 |
| » Lost to Rangers (1-0), 8-3 | Cleveland Stadium (0-1) | 0-1 | |
| » W: Charlie Hough (1-0) L: Rick Waits (0-1) | Fourth | 1 out |
| » Major-league debuts: George Wright (Rangers) |
| Sunday, April 11 |
| » Defeated Rangers (1-1), 13-1 | Cleveland Stadium (1-1) | 1-1 | |
| » W: Len Barker (1-0) L: Doc Medich (0-1) | Second | ½ out |
| Tuesday, April 13 |
| » Lost to Brewers (3-1), 9-8 | Cleveland Stadium (1-2) | 1-2 | |
| » W: Rollie Fingers (1-1) L: Dennis Lewallyn (0-1) | Fourth | 1½ out |
| Wednesday, April 14 |
| » Defeated Brewers (3-2), 6-2 | Cleveland Stadium (2-2) | 2-2 | |
| » W: John Denny (1-0) L: Pete Vuckovich (1-1) | Second | ½ out |
| Thursday, April 15 |
| » Defeated Brewers (3-3), 8-1 | Cleveland Stadium (3-2) | 3-2 | Won 2 |
| » W: Bert Blyleven (1-0) L: Mike Caldwell (0-1) | First | -- |
| Friday, April 16 |
| » Lost to Royals (5-2), 3-1 | Cleveland Stadium (3-3) | 3-3 | |
| » W: Vida Blue (1-1) L: Len Barker (1-1) S: Dan Quisenberry (3) | First | -- |
| Saturday, April 17 |
| » Lost to Royals (6-2), 12-10 | Cleveland Stadium (3-4) | 3-4 | Lost 2 |
| » W: Dave Frost (3-0) L: Rick Waits (0-2) S: Dan Quisenberry (4) | Second | 1 out |
| Sunday, April 18 |
| » Defeated Royals (6-3), 8-2 | Cleveland Stadium (4-4) | 4-4 | |
| » W: John Denny (2-0) L: Bud Black (0-1) | First | -- |
| Tuesday, April 20 |
| » Defeated Rangers (5-4), 9-4 | Arlington Stadium (1-0) | 5-4 | Won 2 |
| » W: Bert Blyleven (2-0) L: Charlie Hough (2-1) | Second | 1½ out |
| Wednesday, April 21 |
| » Lost to Rangers (6-4), 4-2 | Arlington Stadium (1-1) | 5-5 | |
| » W: Doc Medich (1-1) L: Rick Waits (0-3) S: Steve Comer (2) | Second | 1½ out |
| Thursday, April 22 |
| » Defeated Rangers (6-5), 4-3 | Arlington Stadium (2-1) | 6-5 | |
| » W: Len Barker (2-1) L: Frank Tanana (1-2) S: Dan Spillner (1) | Second | 1½ out |
| Friday, April 23 |
| » Lost to Royals (7-6), 11-6 | Royals Stadium (0-1) | 6-6 | |
| » W: Grant Jackson (1-0) L: Lary Sorensen (0-1) | Third | 2½ out |
| Saturday, April 24 |
| » Lost to Royals (8-6), 5-1 | Royals Stadium (0-2) | 6-7 | Lost 2 |
| » W: Paul Splittorff (1-0) L: John Denny (2-1) S: Dan Quisenberry (5) | Fourth | 3½ out |
| Sunday, April 25 |
| » Lost to Royals (9-6), 6-3 | Royals Stadium (0-3) | 6-8 | Lost 3 |
| » W: Larry Gura (2-1) L: Bert Blyleven (2-1) | Fourth | 3½ out |
| Tuesday, April 27 |
| » Lost to Mariners (10-10), 7-4 | Cleveland Stadium (4-5) | 6-9 | Lost 4 |
| » W: Bill Caudill (3-0) L: Dan Spillner (0-1) S: Ed Vande Berg (1) | Third | 4½ out |
| Wednesday, April 28 |
| » Defeated Mariners (10-11), 6-1 | Cleveland Stadium (5-5) | 7-9 | |
| » W: Len Barker (3-1) L: Mike Moore (1-3) | Third | 3½ out |
| Thursday, April 29 |
| » Defeated Mariners (10-12), 5-1 | Cleveland Stadium (6-5) | 8-9 | Won 2 |
| » W: Lary Sorensen (1-1) L: Gene Nelson (0-4) | Fourth | 3 out |
| Friday, April 30 |
| » Lost to Athletics (11-11), 8-0 | Cleveland Stadium (6-6) | 8-10 | |
| » W: Rick Langford (2-3) L: John Denny (2-2) | Fourth | 4 out |
| Saturday, May 1 |
| » Lost to Athletics (12-11), 8-2 | Cleveland Stadium (6-7) | 8-11 | Lost 2 |
| » W: Jeff Jones (3-1) L: Bert Blyleven (2-2) S: Tom Underwood (2) | Fourth | 5 out |
| Sunday, May 2 |
| » Lost to Athletics (13-11), 5-2 | Cleveland Stadium (6-8) | 8-12 | Lost 3 |
| » W: Mike Norris (2-2) L: Rick Waits (0-4) | Sixth | 6 out |
| Monday, May 3 |
| » Lost to Angels (17-8), 5-4 | Cleveland Stadium (6-9) | 8-13 | Lost 4 |
| » W: Don Aase (3-1) L: Dan Spillner (0-2) | Sixth | 7 out |
| Tuesday, May 4 |
| » Defeated Angels (17-9), 6-5 | Cleveland Stadium (7-9) | 9-13 | |
| » W: Lary Sorensen (2-1) L: Geoff Zahn (4-1) S: Dan Spillner (2) | Fourth | 7 out |
| Thursday, May 6 |
| » Lost to Athletics (16-11), 4-2 | Oakland-Alameda County Stadium (0-1) | 9-14 | |
| » W: Steve McCatty (2-1) L: John Denny (2-3) S: Dave Beard (2) | Fourth | 7½ out |
| Friday, May 7 |
| » Defeated Athletics (16-12), 15-6 | Oakland-Alameda County Stadium (1-1) | 10-14 | |
| » W: Rick Sutcliffe (1-0) L: Rick Langford (2-4) S: Ed Whitson (1) | Fourth | 6½ out |
| Saturday, May 8 |
| » Defeated Athletics (16-13), 8-5 | Oakland-Alameda County Stadium (2-1) | 11-14 | Won 2 |
| » W: Len Barker (4-1) L: Mike Norris (2-3) S: Dan Spillner (3) | Fourth | 6½ out |
| Sunday, May 9 |
| » Defeated Athletics (16-14), 14-2 | Oakland-Alameda County Stadium (3-1) | 12-14 | Won 3 |
| » W: Lary Sorensen (3-1) L: Matt Keough (3-3) | Fourth | 6½ out |
| Monday, May 10 |
| » Lost to Mariners (15-17), 6-4 | Kingdome (0-1) | 12-15 | |
| » W: Ed Vande Berg (3-1) L: Rick Sutcliffe (1-1) S: Bill Caudill (5) | Fourth | 7½ out |
| Tuesday, May 11 |
| » Defeated Mariners (15-18), 5-4 | Kingdome (1-1) | 13-15 | |
| » W: Ed Whitson (1-0) L: Bill Caudill (3-1) | Fourth | 6½ out |
| Wednesday, May 12 |
| » Defeated Mariners (15-19), 8-5 | Kingdome (2-1) | 14-15 | Won 2 |
| » W: Rick Sutcliffe (2-1) L: Floyd Bannister (4-2) | Fourth | 6½ out |
| Thursday, May 13 |
| » Lost to Angels (21-13), 3-2 | Anaheim Stadium (0-1) | 14-16 | |
| » W: Andy Hassler (1-0) L: Dan Spillner (0-3) | Fourth | 6½ out |
| Friday, May 14 |
| » Lost to Angels (22-13), 5-2 | Anaheim Stadium (0-2) | 14-17 | Lost 2 |
| » W: Bruce Kison (2-0) L: Lary Sorensen (3-2) S: Doug Corbett (4) | Fifth | 7 out |
| Saturday, May 15 |
| » Lost to Angels (23-13), 9-6 | Anaheim Stadium (0-3) | 14-18 | Lost 3 |
| » W: Mike Witt (3-0) L: Tom Brennan (0-1) S: Doug Corbett (5) | Fifth | 8 out |
| Sunday, May 16 |
| » Lost to Angels (24-13), 3-0 | Anaheim Stadium (0-4) | 14-19 | Lost 4 |
| » W: Ken Forsch (3-3) L: John Denny (2-4) | Fifth | 8 out |
| Tuesday, May 18 |
| » Defeated Blue Jays (14-21), 6-5 | Cleveland Stadium (8-9) | 15-19 | |
| » W: Dan Spillner (1-3) L: Dale Murray (2-2) | Fifth | 7 out |
| Wednesday, May 19 |
| » Lost to Blue Jays (15-21), 8-5 | Cleveland Stadium (8-10) | 15-20 | |
| » W: Jerry Garvin (1-0) L: Len Barker (4-2) S: Joey McLaughlin (2) | Fifth | 8 out |
| Thursday, May 20 |
| » Lost to Blue Jays (16-21), 2-0 | Cleveland Stadium (8-11) | 15-21 | Lost 2 |
| » W: Jim Clancy (5-2) L: Lary Sorensen (3-3) | Seventh | 9 out |
| Friday, May 21 |
| » Lost to White Sox (25-12), 3-2 | Comiskey Park I (0-1) | 15-22 | Lost 3 |
| » W: Britt Burns (5-2) L: Dan Spillner (1-4) | Seventh | 10 out |
| Saturday, May 22 |
| » Lost to White Sox (26-12), 7-3 | Comiskey Park I (0-2) | 15-23 | Lost 4 |
| » W: Steve Trout (4-3) L: John Denny (2-5) S: Jerry Koosman (3) | Seventh | 11 out |
| Sunday, May 23 |
| » Defeated White Sox (26-13), 6-4 | Comiskey Park I (1-2) | 16-23 | |
| » W: Dan Spillner (2-4) L: Jerry Koosman (1-2) | Sixth | 11 out |
| Monday, May 24 |
| » Defeated Twins (12-33), 9-2 | Hubert H. Humphrey Metrodome (1-0) | 17-23 | Won 2 |
| » W: Len Barker (5-2) L: Pete Redfern (2-6) | Fifth | 10½ out |
| Tuesday, May 25 |
| » Defeated Twins (12-34), 7-0 | Hubert H. Humphrey Metrodome (2-0) | 18-23 | Won 3 |
| » W: Lary Sorensen (4-3) L: Brad Havens (1-3) | Sixth | 9½ out |
| Wednesday, May 26 |
| » Defeated Twins (12-35), 2-1 | Hubert H. Humphrey Metrodome (3-0) | 19-23 | Won 4 |
| » W: Dan Spillner (3-4) L: Ron Davis (1-4) | Sixth | 9 out |
| Friday, May 28 |
| » Defeated White Sox (28-15), 5-2 | Cleveland Stadium (9-11) | 20-23 | Won 5 |
| » W: John Denny (3-5) L: Steve Trout (4-4) | Fifth | 8½ out |
| Future Indian Jhonny Peralta is born in Santiago, D.R. |
| Saturday, May 29 |
| » Defeated White Sox (28-16), 5-2 | Cleveland Stadium (10-11) | 21-23 | Won 6 |
| » W: Rick Sutcliffe (3-1) L: La Marr Hoyt (9-1) S: Dan Spillner (4) | Fifth | 7½ out |
| Sunday, May 30 |
| » Defeated White Sox (28-17), 4-2 | Cleveland Stadium (11-11) | 22-23 | Won 7 |
| » W: Len Barker (6-2) L: Dennis Lamp (4-1) | Fourth | 6½ out |
| Monday, May 31 |
| » Defeated Twins (12-39), 9-4 | Cleveland Stadium (12-11) | 23-23 | Won 8 |
| » W: Lary Sorensen (5-3) L: Pete Filson (0-2) | Fourth | 6½ out |
| Tuesday, June 1 |
| » Defeated Twins (12-40), 6-4 | Cleveland Stadium (13-11) | 24-23 | Won 9 |
| » W: Ed Glynn (1-0) L: Ron Davis (1-6) S: Dan Spillner (5) | Fourth | 6 out |
| Wednesday, June 2 |
| » Defeated Twins (12-41), 4-2 | Cleveland Stadium (14-11) | 25-23 | Won 10 |
| » W: Rick Sutcliffe (4-1) L: Bobby Castillo (2-3) S: Ed Whitson (2) | Fourth | 6 out |
| Friday, June 4 |
| » Defeated Blue Jays (23-28), 6-3 | Exhibition Stadium (1-0) | 26-23 | Won 11 |
| » W: Len Barker (7-2) L: Dale Murray (3-3) S: Dan Spillner (6) | Third | 5 out |
| Sunday, June 6 |
| » Lost to Blue Jays (24-28), 5-1 | Exhibition Stadium (1-1) | 26-24 | |
| » W: Dave Stieb (5-5) L: Lary Sorensen (5-4) | Third | 5½ out |
| » Defeated Blue Jays (24-29), 7-5 | Exhibition Stadium (2-1) | 27-24 | |
| » W: Ed Glynn (2-0) L: Jerry Garvin (1-1) S: Dan Spillner (7) | Third | 5½ out |
| Monday, June 7 |
| » Lost to Blue Jays (25-29), 7-3 | Exhibition Stadium (2-2) | 27-25 | |
| » W: Luis Leal (5-3) L: John Denny (3-6) | Third | 6 out |
| Tuesday, June 8 |
| » Lost to Tigers (33-18), 8-3 | Tiger Stadium (0-1) | 27-26 | Lost 2 |
| » W: Pat Underwood (3-3) L: Rick Sutcliffe (4-2) | Third | 7 out |
| Wednesday, June 9 |
| » Lost to Tigers (34-18), 2-1 | Tiger Stadium (0-2) | 27-27 | Lost 3 |
| » W: Jack Morris (8-5) L: Len Barker (7-3) | Fourth | 8 out |
| » Game at Tiger Stadium interrupted in the 15th inning with the score of Indians 3, Tigers 3. Completed on September 24. |
| Friday, June 11 |
| » Lost to Red Sox (36-20), 6-2 | Fenway Park (0-1) | 27-28 | Lost 4 |
| » W: Tom Burgmeier (3-0) L: Lary Sorensen (5-5) | Fourth | 8½ out |
| » Major-league debuts: Bud Anderson (Indians) |
| Saturday, June 12 |
| » Lost to Red Sox (37-20), 6-4 | Fenway Park (0-2) | 27-29 | Lost 5 |
| » W: Bob Stanley (5-1) L: John Denny (3-7) | Fifth | 9½ out |
| Monday, June 14 |
| » Defeated Tigers (35-21), 5-0 | Cleveland Stadium (15-11) | 28-29 | |
| » W: Len Barker (8-3) L: Jack Morris (8-6) | Fifth | 8 out |
| » Defeated Tigers (35-22), 2-1 | Cleveland Stadium (16-11) | 29-29 | Won 2 |
| » W: Rick Sutcliffe (5-2) L: Jerry Ujdur (0-1) S: Dan Spillner (8) | Fifth | 8 out |
| Thursday, June 17 |
| » Lost to Red Sox (38-23), 6-3 | Cleveland Stadium (16-12) | 29-30 | |
| » W: Mike Torrez (4-3) L: Lary Sorensen (5-6) S: Mark Clear (11) | Sixth | 8 out |
| Friday, June 18 |
| » Defeated Red Sox (38-24), 10-3 | Cleveland Stadium (17-12) | 30-30 | |
| » W: John Denny (4-7) L: Dennis Eckersley (6-6) | Fifth | 7 out |
| Saturday, June 19 |
| » Lost to Red Sox (39-24), 7-3 | Cleveland Stadium (17-13) | 30-31 | |
| » W: Chuck Rainey (4-2) L: Rick Sutcliffe (5-3) S: Bob Stanley (4) | Sixth | 8 out |
| Sunday, June 20 |
| » Defeated Red Sox (39-25), 5-4 | Cleveland Stadium (18-13) | 31-31 | |
| » W: Dan Spillner (4-4) L: Luis Aponte (2-1) | Fifth | 7 out |
| Monday, June 21 |
| » Lost to Orioles (34-29), 7-0 | Cleveland Stadium (18-14) | 31-32 | |
| » W: Dennis Martinez (7-4) L: Rick Waits (0-5) | Fifth | 8 out |
| Tuesday, June 22 |
| » Defeated Orioles (34-30), 8-6 | Cleveland Stadium (19-14) | 32-32 | |
| » W: Lary Sorensen (6-6) L: Sammy Stewart (5-5) | Fifth | 8 out |
| Wednesday, June 23 |
| » Lost to Orioles (35-30), 3-1 | Cleveland Stadium (19-15) | 32-33 | |
| » W: Jim Palmer (5-3) L: John Denny (4-8) S: Tim Stoddard (5) | Fifth | 9 out |
| Thursday, June 24 |
| » Defeated Yankees (31-34), 5-2 | Yankee Stadium (1-0) | 33-33 | |
| » W: Dan Spillner (5-4) L: Ron Guidry (8-2) | Fifth | 8½ out |
| Friday, June 25 |
| » Lost to Yankees (32-34), 11-3 | Yankee Stadium (1-1) | 33-34 | |
| » W: Tommy John (5-6) L: Len Barker (8-4) | Fifth | 8½ out |
| » Major-league debuts: Juan Espino (Yankees) |
| Saturday, June 26 |
| » Lost to Yankees (33-34), 4-3 | Yankee Stadium (1-2) | 33-35 | Lost 2 |
| » W: Dave LaRoche (2-1) L: Ed Whitson (1-1) | Sixth | 8½ out |
| Sunday, June 27 |
| » Defeated Yankees (33-35), 4-3 | Yankee Stadium (2-2) | 34-35 | |
| » W: Lary Sorensen (7-6) L: Roger Erickson (4-7) S: Rick Sutcliffe (1) | Fifth | 7½ out |
| Tuesday, June 29 |
| » Defeated Orioles (38-32), 9-2 | Memorial Stadium (1-0) | 35-35 | Won 2 |
| » W: John Denny (5-8) L: Scott McGregor (8-6) | Fifth | 8 out |
| Wednesday, June 30 |
| » Defeated Orioles (38-33), 9-0 | Memorial Stadium (2-0) | 36-35 | Won 3 |
| » W: Rick Sutcliffe (6-3) L: Mike Flanagan (6-6) | Fifth | 7 out |
| Thursday, July 1 |
| » Defeated Orioles (38-34), 6-2 | Memorial Stadium (3-0) | 37-35 | Won 4 |
| » W: Len Barker (9-4) L: Dennis Martinez (8-5) S: Dan Spillner (9) | Fifth | 6 out |
| Friday, July 2 |
| » Lost to Yankees (35-37), 3-1 | Cleveland Stadium (19-16) | 37-36 | |
| » W: Roger Erickson (5-7) L: Rick Waits (0-6) S: Rich Gossage (14) | Fifth | 6 out |
| Saturday, July 3 |
| » Lost to Yankees (36-37), 10-6 | Cleveland Stadium (19-17) | 37-37 | Lost 2 |
| » W: George Frazier (2-1) L: Dan Spillner (5-5) S: Rich Gossage (15) | Fourth | 6 out |
| Sunday, July 4 |
| » Lost to Yankees (37-37), 3-2 | Cleveland Stadium (19-18) | 37-38 | Lost 3 |
| » W: George Frazier (3-1) L: John Denny (5-9) S: Roger Erickson (1) | Sixth | 7 out |
| Monday, July 5 |
| » Lost to Athletics (35-47), 2-0 | Oakland-Alameda County Stadium (3-2) | 37-39 | Lost 4 |
| » W: Tom Underwood (4-4) L: Rick Sutcliffe (6-4) S: Dave Beard (7) | Sixth | 7½ out |
| Tuesday, July 6 |
| » Lost to Athletics (36-47), 7-3 | Oakland-Alameda County Stadium (3-3) | 37-40 | Lost 5 |
| » W: Brian Kingman (1-5) L: Len Barker (9-5) | Sixth | 7½ out |
| Wednesday, July 7 |
| » Defeated Angels (45-37), 8-6 | Anaheim Stadium (1-4) | 38-40 | |
| » W: Rick Waits (1-6) L: Mike Witt (4-3) S: Dan Spillner (10) | Sixth | 7½ out |
| Thursday, July 8 |
| » Lost to Angels (46-37), 5-1 | Anaheim Stadium (1-5) | 38-41 | |
| » W: Dave Goltz (2-3) L: Lary Sorensen (7-7) S: Doug Corbett (10) | Sixth | 8½ out |
| Friday, July 9 |
| » Defeated Mariners (45-39), 7-4 | Kingdome (3-1) | 39-41 | |
| » W: John Denny (6-9) L: Floyd Bannister (8-5) S: Dan Spillner (11) | Sixth | 7½ out |
| Saturday, July 10 |
| » Defeated Mariners (45-40), 7-1 | Kingdome (4-1) | 40-41 | Won 2 |
| » W: Rick Sutcliffe (7-4) L: Jim Beattie (6-5) | Fifth | 7½ out |
| Sunday, July 11 |
| » Defeated Mariners (45-41), 4-3 | Kingdome (5-1) | 41-41 | Won 3 |
| » W: Len Barker (10-5) L: Bill Caudill (8-4) | Fifth | 6½ out |
| Thursday, July 15 |
| » Lost to Angels (50-37), 8-2 | Cleveland Stadium (19-19) | 41-42 | |
| » W: Dave Goltz (3-3) L: Rick Waits (1-7) | Fifth | 8 out |
| Friday, July 16 |
| » Lost to Angels (51-37), 15-0 | Cleveland Stadium (19-20) | 41-43 | Lost 2 |
| » W: Ken Forsch (9-7) L: John Denny (6-10) | Sixth | 9 out |
| Saturday, July 17 |
| » Defeated Angels (51-38), 10-4 | Cleveland Stadium (20-20) | 42-43 | |
| » W: Ed Glynn (3-0) L: Doug Corbett (1-8) | Sixth | 9 out |
| » Major-league debuts: Carmen Castillo (Indians) |
| Sunday, July 18 |
| » Defeated Angels (51-39), 5-4 | Cleveland Stadium (21-20) | 43-43 | Won 2 |
| » W: Ed Glynn (4-0) L: Doug Corbett (1-9) | Sixth | 9 out |
| Monday, July 19 |
| » Defeated Athletics (38-55), 5-4 | Cleveland Stadium (22-20) | 44-43 | Won 3 |
| » W: Dan Spillner (6-5) L: Dave Beard (5-7) | Sixth | 8 out |
| Tuesday, July 20 |
| » Lost to Athletics (39-55), 6-4 | Cleveland Stadium (22-21) | 44-44 | |
| » W: Mike Norris (5-6) L: Rick Waits (1-8) | Fifth | 8 out |
| Wednesday, July 21 |
| » Lost to Athletics (40-55), 6-4 | Cleveland Stadium (22-22) | 44-45 | Lost 2 |
| » W: Tom Underwood (6-4) L: John Denny (6-11) S: Brian Kingman (1) | Sixth | 9 out |
| Friday, July 23 |
| » Defeated Mariners (48-46), 4-3 | Cleveland Stadium (23-22) | 45-45 | |
| » W: Dan Spillner (7-5) L: Ed Vande Berg (5-4) | Sixth | 8 out |
| Saturday, July 24 |
| » Lost to Mariners (49-46), 9-0 | Cleveland Stadium (23-23) | 45-46 | |
| » W: Mike Moore (5-7) L: Len Barker (10-6) | Sixth | 9 out |
| Sunday, July 25 |
| » Defeated Mariners (49-47), 5-3 | Cleveland Stadium (24-23) | 46-46 | |
| » W: Lary Sorensen (8-7) L: Jim Beattie (6-7) S: Dan Spillner (12) | Sixth | 8 out |
| Monday, July 26 |
| » Lost to Royals (52-43), 8-1 | Cleveland Stadium (24-24) | 46-47 | |
| » W: Vida Blue (8-7) L: Tom Brennan (0-2) | Sixth | 8½ out |
| Tuesday, July 27 |
| » Lost to Royals (53-43), 8-1 | Cleveland Stadium (24-25) | 46-48 | Lost 2 |
| » W: Dave Frost (5-4) L: Rick Waits (1-9) | Sixth | 9 out |
| Wednesday, July 28 |
| » Defeated Royals (53-44), 4-2 | Cleveland Stadium (25-25) | 47-48 | |
| » W: Rick Sutcliffe (8-4) L: Bill Castro (0-1) S: Dan Spillner (13) | Sixth | 9 out |
| Thursday, July 29 |
| » Defeated Brewers (57-41), 5-1 | County Stadium (1-0) | 48-48 | Won 2 |
| » W: Dan Spillner (8-5) L: Jim Slaton (7-2) | Sixth | 8½ out |
| Friday, July 30 |
| » Defeated Brewers (57-42), 7-2 | County Stadium (2-0) | 49-48 | Won 3 |
| » W: Lary Sorensen (9-7) L: Randy Lerch (7-7) | Sixth | 7½ out |
| Saturday, July 31 |
| » Lost to Brewers (58-42), 4-2 | County Stadium (2-1) | 49-49 | |
| » W: Mike Caldwell (8-10) L: Rick Waits (1-10) S: Rollie Fingers (23) | Sixth | 8 out |
| Sunday, August 1 |
| » Defeated Brewers (58-43), 4-1 | County Stadium (3-1) | 50-49 | |
| » W: Ed Whitson (2-1) L: Moose Haas (8-6) S: Dan Spillner (14) | Sixth | 8 out |
| » Lost to Brewers (59-43), 7-2 | County Stadium (3-2) | 50-50 | |
| » W: Jim Slaton (8-2) L: Bud Anderson (0-1) | Sixth | 8 out |
| Monday, August 2 |
| » Defeated Rangers (40-60), 6-2 | Cleveland Stadium (26-25) | 51-50 | |
| » W: Rick Sutcliffe (9-4) L: Frank Tanana (5-12) | Fourth | 7 out |
| Future Indian Grady Sizemore is born in Seattle, WA. |
| Tuesday, August 3 |
| » Defeated Rangers (40-61), 2-0 | Cleveland Stadium (27-25) | 52-50 | Won 2 |
| » W: Len Barker (11-6) L: Dave Schmidt (2-3) S: Dan Spillner (15) | Fourth | 7½ out |
| » Lost to Rangers (41-61), 5-4 | Cleveland Stadium (27-26) | 52-51 | |
| » W: Jon Matlack (5-5) L: Dan Spillner (8-6) S: Steve Comer (6) | Fourth | 7½ out |
| Wednesday, August 4 |
| » Defeated Rangers (41-62), 8-4 | Cleveland Stadium (28-26) | 53-51 | |
| » W: Bud Anderson (1-1) L: Doc Medich (7-10) | Fourth | 7½ out |
| Friday, August 6 |
| » Lost to Brewers (62-44), 5-2 | Cleveland Stadium (28-27) | 53-52 | |
| » W: Moose Haas (9-6) L: Ed Glynn (4-1) S: Rollie Fingers (25) | Fifth | 8½ out |
| Saturday, August 7 |
| » Defeated Brewers (62-45), 4-3 | Cleveland Stadium (29-27) | 54-52 | |
| » W: Ed Glynn (5-1) L: Jim Slaton (8-3) | Fifth | 7½ out |
| Sunday, August 8 |
| » Lost to Brewers (63-45), 7-6 | Cleveland Stadium (29-28) | 54-53 | |
| » W: Dwight Bernard (3-1) L: Len Barker (11-7) S: Rollie Fingers (26) | Fifth | 8½ out |
| Monday, August 9 |
| » Lost to Royals (62-48), 12-2 | Royals Stadium (0-4) | 54-54 | Lost 2 |
| » W: Larry Gura (13-8) L: Lary Sorensen (9-8) | Fifth | 9½ out |
| Tuesday, August 10 |
| » Lost to Royals (63-48), 5-1 | Royals Stadium (0-5) | 54-55 | Lost 3 |
| » W: Mike Armstrong (4-4) L: Rick Waits (1-11) | Sixth | 10½ out |
| Wednesday, August 11 |
| » Lost to Royals (64-48), 8-0 | Royals Stadium (0-6) | 54-56 | Lost 4 |
| » W: Don Hood (4-0) L: Ed Whitson (2-2) | Sixth | 10½ out |
| Friday, August 13 |
| » Lost to Rangers (45-67), 8-7 | Arlington Stadium (2-2) | 54-57 | Lost 5 |
| » W: Danny Darwin (8-6) L: Dan Spillner (8-7) | Sixth | 12½ out |
| Saturday, August 14 |
| » Lost to Rangers (46-67), 3-2 | Arlington Stadium (2-3) | 54-58 | Lost 6 |
| » W: John Butcher (1-2) L: Len Barker (11-8) | Sixth | 12½ out |
| Sunday, August 15 |
| » Defeated Rangers (46-68), 6-4 | Arlington Stadium (3-3) | 55-58 | |
| » W: Lary Sorensen (10-8) L: Charlie Hough (11-10) S: Ed Glynn (1) | Sixth | 11½ out |
| Monday, August 16 |
| » Lost to Blue Jays (58-61), 2-1 | Exhibition Stadium (2-3) | 55-59 | |
| » W: Jim Gott (4-8) L: Rick Waits (1-12) S: Joey McLaughlin (8) | Seventh | 12 out |
| Tuesday, August 17 |
| » Defeated Blue Jays (58-62), 6-5 | Exhibition Stadium (3-3) | 56-59 | |
| » W: Dan Spillner (9-7) L: Joey McLaughlin (8-5) | Sixth | 10½ out |
| » Defeated Blue Jays (58-63), 9-5 | Exhibition Stadium (4-3) | 57-59 | Won 2 |
| » W: Rick Sutcliffe (10-4) L: Dave Geisel (1-1) | Sixth | 10½ out |
| Friday, August 20 |
| » Defeated Twins (42-79), 7-5 | Cleveland Stadium (30-28) | 58-59 | Won 3 |
| » W: Len Barker (12-8) L: Pete Redfern (5-10) S: Dan Spillner (16) | Sixth | 10½ out |
| Saturday, August 21 |
| » Lost to Twins (43-79), 4-3 | Cleveland Stadium (30-29) | 58-60 | |
| » W: Albert Williams (4-7) L: Lary Sorensen (10-9) S: Ron Davis (16) | Sixth | 11½ out |
| Sunday, August 22 |
| » Defeated Twins (43-80), 4-3 | Cleveland Stadium (31-29) | 59-60 | |
| » W: Rick Sutcliffe (11-4) L: Jack O'Connor (5-5) | Sixth | 11½ out |
| Monday, August 23 |
| » Defeated White Sox (65-58), 5-4 | Cleveland Stadium (32-29) | 60-60 | Won 2 |
| » W: Dan Spillner (10-7) L: Chico Escarrega (1-3) | Sixth | 10½ out |
| Tuesday, August 24 |
| » Defeated White Sox (65-59), 14-7 | Cleveland Stadium (33-29) | 61-60 | Won 3 |
| » W: Rick Waits (2-12) L: La Marr Hoyt (14-12) S: Tom Brennan (1) | Sixth | 10½ out |
| Wednesday, August 25 |
| » Lost to White Sox (66-59), 5-1 | Cleveland Stadium (33-30) | 61-61 | |
| » W: Richard Dotson (8-11) L: Len Barker (12-9) S: Sparky Lyle (3) | Fifth | 11 out |
| Friday, August 27 |
| » Lost to Twins (45-82), 5-3 | Hubert H. Humphrey Metrodome (3-1) | 61-62 | Lost 2 |
| » W: Albert Williams (5-7) L: Lary Sorensen (10-10) S: Ron Davis (17) | Fifth | 12½ out |
| Saturday, August 28 |
| » Lost to Twins (46-82), 10-0 | Hubert H. Humphrey Metrodome (3-2) | 61-63 | Lost 3 |
| » W: Jack O'Connor (6-5) L: Rick Sutcliffe (11-5) | Fifth | 12½ out |
| Sunday, August 29 |
| » Lost to Twins (47-82), 6-3 | Hubert H. Humphrey Metrodome (3-3) | 61-64 | Lost 4 |
| » W: Bobby Castillo (8-10) L: Dan Spillner (10-8) | Fifth | 13½ out |
| Monday, August 30 |
| » Lost to White Sox (67-62), 4-1 | Comiskey Park I (1-3) | 61-65 | Lost 5 |
| » W: Richard Dotson (9-11) L: Rick Waits (2-13) S: Jim Kern (3) | Sixth | 13½ out |
| Tuesday, August 31 |
| » Lost to White Sox (68-62), 14-6 | Comiskey Park I (1-4) | 61-66 | Lost 6 |
| » W: Kevin Hickey (4-2) L: Len Barker (12-10) | Sixth | 14½ out |
| Wednesday, September 1 |
| » Lost to White Sox (69-62), 6-0 | Comiskey Park I (1-5) | 61-67 | Lost 7 |
| » W: Jerry Koosman (7-6) L: Lary Sorensen (10-11) | Sixth | 15½ out |
| Thursday, September 2 |
| » Lost to Brewers (79-53), 2-1 | County Stadium (3-3) | 61-68 | Lost 8 |
| » W: Moose Haas (10-8) L: Rick Sutcliffe (11-6) S: Pete Ladd (2) | Fifth | 15½ out |
| » Defeated Brewers (79-54), 4-2 | County Stadium (4-3) | 62-68 | |
| » W: Dan Spillner (11-8) L: Don Sutton (13-9) | Fifth | 15½ out |
| Friday, September 3 |
| » Defeated Blue Jays (61-74), 3-2 | Cleveland Stadium (34-30) | 63-68 | Won 2 |
| » W: Bud Anderson (2-1) L: Jim Clancy (11-13) S: Tom Brennan (2) | Sixth | 14½ out |
| » Major-league debuts: Neal Heaton (Indians) |
| Saturday, September 4 |
| » Defeated Blue Jays (61-75), 4-3 | Cleveland Stadium (35-30) | 64-68 | Won 3 |
| » W: Tom Brennan (1-2) L: Dale Murray (8-5) S: Dan Spillner (17) | Fifth | 14½ out |
| » Major-league debuts: Geno Petralli (Blue Jays) |
| Sunday, September 5 |
| » Lost to Blue Jays (62-75), 6-5 | Cleveland Stadium (35-31) | 64-69 | |
| » W: Luis Leal (10-12) L: Len Barker (12-11) S: Dale Murray (6) | Fifth | 15½ out |
| Monday, September 6 |
| » Lost to Red Sox (77-59), 10-3 | Cleveland Stadium (35-32) | 64-70 | Lost 2 |
| » W: Mike Torrez (8-8) L: Lary Sorensen (10-12) S: Bob Stanley (13) | Sixth | 15½ out |
| » Major-league debuts: Marty Barrett (Red Sox) |
| Tuesday, September 7 |
| » Defeated Red Sox (77-60), 5-4 | Cleveland Stadium (36-32) | 65-70 | |
| » W: Dan Spillner (12-8) L: Mark Clear (13-8) | Sixth | 15½ out |
| Wednesday, September 8 |
| » Defeated Red Sox (77-61), 2-0 | Cleveland Stadium (37-32) | 66-70 | Won 2 |
| » W: Ed Whitson (3-2) L: John Tudor (10-10) | Fifth | 15½ out |
| Thursday, September 9 |
| » Defeated Orioles (78-60), 3-0 | Cleveland Stadium (38-32) | 67-70 | Won 3 |
| » W: Bud Anderson (3-1) L: Dennis Martinez (14-11) | Sixth | 14½ out |
| Friday, September 10 |
| » Lost to Orioles (79-60), 3-2 | Cleveland Stadium (38-33) | 67-71 | |
| » W: Sammy Stewart (8-7) L: Dan Spillner (12-9) | Sixth | 15½ out |
| Saturday, September 11 |
| » Lost to Orioles (80-60), 8-1 | Cleveland Stadium (38-34) | 67-72 | Lost 2 |
| » W: Mike Flanagan (14-10) L: Lary Sorensen (10-13) | Sixth | 15½ out |
| Sunday, September 12 |
| » Defeated Orioles (80-61), 3-0 | Cleveland Stadium (39-34) | 68-72 | |
| » W: Rick Sutcliffe (12-6) L: Tippy Martinez (8-7) | Sixth | 14½ out |
| Monday, September 13 |
| » Defeated Red Sox (79-63), 3-1 | Fenway Park (1-2) | 69-72 | Won 2 |
| » W: Ed Whitson (4-2) L: Oil Can Boyd (0-1) S: Dan Spillner (18) | Sixth | 13 out |
| » Defeated Red Sox (79-64), 4-3 | Fenway Park (2-2) | 70-72 | Won 3 |
| » W: Tom Brennan (2-2) L: Luis Aponte (2-2) | Sixth | 13 out |
| » Major-league debuts: Oil Can Boyd (Red Sox) |
| Tuesday, September 14 |
| » Lost to Red Sox (80-64), 12-1 | Fenway Park (2-3) | 70-73 | |
| » W: John Tudor (11-10) L: Neal Heaton (0-1) | Sixth | 14 out |
| Wednesday, September 15 |
| » Defeated Red Sox (80-65), 7-4 | Fenway Park (3-3) | 71-73 | |
| » W: Len Barker (13-11) L: Dennis Eckersley (12-12) S: Dan Spillner (19) | Sixth | 14 out |
| Thursday, September 16 |
| » Major-league debuts: Mike Brown (Red Sox) |
| Friday, September 17 |
| » Defeated Orioles (85-62), 5-3 | Memorial Stadium (4-0) | 72-73 | Won 2 |
| » W: Rick Sutcliffe (13-6) L: Dennis Martinez (14-12) S: Ed Glynn (2) | Fifth | 14 out |
| Saturday, September 18 |
| » Lost to Orioles (86-62), 5-2 | Memorial Stadium (4-1) | 72-74 | |
| » W: Scott McGregor (14-12) L: Bud Anderson (3-2) | Fifth | 15 out |
| Sunday, September 19 |
| » Lost to Orioles (87-62), 4-2 | Memorial Stadium (4-2) | 72-75 | Lost 2 |
| » W: Mike Flanagan (15-10) L: Ed Glynn (5-2) | Fifth | 16 out |
| Tuesday, September 21 |
| » Defeated Yankees (73-77), 9-8 | Yankee Stadium (3-2) | 73-75 | |
| » W: Jerry Reed (2-0) L: Rudy May (6-5) S: Ed Glynn (3) | Fifth | 16 out |
| » Lost to Yankees (74-77), 6-2 | Yankee Stadium (3-3) | 73-76 | |
| » W: Dave Righetti (10-9) L: Lary Sorensen (10-14) | Fifth | 16 out |
| Wednesday, September 22 |
| » Defeated Yankees (74-78), 5-0 | Yankee Stadium (4-3) | 74-76 | |
| » W: Rick Sutcliffe (14-6) L: Doyle Alexander (0-7) | Fifth | 16 out |
| Friday, September 24 |
| » Defeated Tigers (76-75), 6-2 | Tiger Stadium (1-2) | 75-76 | Won 2 |
| » W: Tom Brennan (3-2) L: Jerry Ujdur (9-10) S: Dan Spillner (20) | Fifth | 16½ out |
| » Lost to Tigers (77-75), 4-3 | Tiger Stadium (1-3) | 75-77 | |
| » W: Larry Pashnick (4-4) L: Bud Anderson (3-3) | Fifth | 16½ out |
| Saturday, September 25 |
| » Lost to Tigers (78-75), 4-0 | Tiger Stadium (1-4) | 75-78 | Lost 2 |
| » W: Jack Morris (17-16) L: Neal Heaton (0-2) | Fifth | 16½ out |
| Sunday, September 26 |
| » Defeated Tigers (78-76), 4-3 | Tiger Stadium (2-4) | 76-78 | |
| » W: Len Barker (14-11) L: Milt Wilcox (12-9) S: Ed Glynn (4) | Fifth | 15½ out |
| Tuesday, September 28 |
| » Lost to Yankees (77-80), 6-4 | Cleveland Stadium (39-35) | 76-79 | |
| » W: Doyle Alexander (1-7) L: Rick Sutcliffe (14-7) S: Rich Gossage (29) | Fifth | 16½ out |
| Wednesday, September 29 |
| » Lost to Yankees (78-80), 13-6 | Cleveland Stadium (39-36) | 76-80 | Lost 2 |
| » W: Jay Howell (2-3) L: Lary Sorensen (10-15) S: George Frazier (1) | Sixth | 17½ out |
| Thursday, September 30 |
| » Lost to Yankees (79-80), 7-5 | Cleveland Stadium (39-37) | 76-81 | Lost 3 |
| » W: Mike Morgan (7-10) L: Dan Spillner (12-10) S: Rich Gossage (30) | Sixth | 17½ out |
| Friday, October 1 |
| » Defeated Tigers (80-78), 3-2 | Cleveland Stadium (40-37) | 77-81 | |
| » W: Len Barker (15-11) L: Milt Wilcox (12-10) | Sixth | 16½ out |
| » Lost to Tigers (81-78), 4-2 | Cleveland Stadium (40-38) | 77-82 | |
| » W: Pat Underwood (4-8) L: Bud Anderson (3-4) S: Howard Bailey (1) | Sixth | 16½ out |
| Saturday, October 2 |
| » Defeated Tigers (81-79), 2-0 | Cleveland Stadium (41-38) | 78-82 | |
| » W: Tom Brennan (4-2) L: Dan Petry (15-9) S: Dan Spillner (21) | Fifth | 16 out |
| » Lost to Tigers (82-79), 4-1 | Cleveland Stadium (41-39) | 78-83 | |
| » W: Dave Rucker (5-6) L: Jerry Reed (2-1) | Fifth | 16 out |
| Sunday, October 3 |
| » Lost to Tigers (83-79), 9-1 | Cleveland Stadium (41-40) | 78-84 | Lost 2 |
| » W: Jerry Ujdur (10-10) L: Rick Sutcliffe (14-8) | Sixth | 17 out |
| Tuesday, October 26 |
| Former Indian Bud Podbielan dies in Syracuse, NY at the age of 59. |
| Tuesday, November 2 |
| Former Indian Bill Zuber dies in Cedar Rapids, IA at the age of 70. |
| Monday, November 29 |
| Former Indian Al Cicotte dies in Westland, MI at the age of 53. |
Game information provided by Retrosheet (www.retrosheet.org) |