| Tuesday, April 6 |
| » Defeated Astros (0-1), 14-3 | Astrodome (1-0) | 1-0 | |
| » W: Bob Forsch (1-0) L: Nolan Ryan (0-1) | First | -- |
| Wednesday, April 7 |
| » Lost to Astros (1-1), 3-2 | Astrodome (1-1) | 1-1 | |
| » W: Joe Niekro (1-0) L: John Martin (0-1) S: Joe Sambito (1) | Second | 1 out |
| Thursday, April 8 |
| » Lost to Astros (2-1), 1-0 | Astrodome (1-2) | 1-2 | Lost 2 |
| » W: Bob Knepper (1-0) L: Joaquin Andujar (0-1) S: Dave Smith (1) | Fourth | 1 out |
| Saturday, April 10 |
| » Lost to Pirates (1-0), 11-7 | Busch Stadium II (0-1) | 1-3 | Lost 3 |
| » W: Rod Scurry (1-0) L: Mark Littell (0-1) S: John Candelaria (1) | Fifth | 2 out |
| Sunday, April 11 |
| » Defeated Pirates (1-1), 7-6 | Busch Stadium II (1-1) | 2-3 | |
| » W: Jim Kaat (1-0) L: Enrique Romo (0-1) | Fourth | 1½ out |
| Monday, April 12 |
| » Defeated Pirates (1-2), 5-4 | Busch Stadium II (2-1) | 3-3 | Won 2 |
| » W: John Martin (1-1) L: Tom Griffin (0-1) S: Bruce Sutter (1) | Third | 1½ out |
| Tuesday, April 13 |
| » Defeated Cubs (3-4), 4-3 | Wrigley Field (1-0) | 4-3 | Won 3 |
| » W: Joaquin Andujar (1-1) L: Randy Martz (0-1) S: Bruce Sutter (2) | Third | ½ out |
| Wednesday, April 14 |
| » Defeated Cubs (3-5), 3-1 | Wrigley Field (2-0) | 5-3 | Won 4 |
| » W: Andy Rincon (1-0) L: Fergie Jenkins (1-1) | Third | 2 out |
| Thursday, April 15 |
| » Defeated Cubs (3-6), 6-1 | Wrigley Field (3-0) | 6-3 | Won 5 |
| » W: Steve Mura (1-0) L: Doug Bird (1-2) | First | -- |
| Friday, April 16 |
| » Defeated Phillies (2-6), 3-2 | Busch Stadium II (3-1) | 7-3 | Won 6 |
| » W: Bob Forsch (2-0) L: Mike Krukow (1-1) S: Bruce Sutter (3) | First | -- |
| Saturday, April 17 |
| » Defeated Phillies (2-7), 6-0 | Busch Stadium II (4-1) | 8-3 | Won 7 |
| » W: Joaquin Andujar (2-1) L: Steve Carlton (0-3) | First | -- |
| Sunday, April 18 |
| » Defeated Phillies (2-8), 6-5 | Busch Stadium II (5-1) | 9-3 | Won 8 |
| » W: Dave LaPoint (1-0) L: Warren Brusstar (1-1) | First | -- |
| Tuesday, April 20 |
| » Defeated Pirates (3-6), 7-4 | Three Rivers Stadium (1-0) | 10-3 | Won 9 |
| » W: John Martin (2-1) L: Rick Rhoden (0-1) S: Bruce Sutter (4) | First | -- |
| Wednesday, April 21 |
| » Defeated Pirates (3-7), 6-2 | Three Rivers Stadium (2-0) | 11-3 | Won 10 |
| » W: Steve Mura (2-0) L: John Candelaria (0-1) S: Bruce Sutter (5) | First | -- |
| Friday, April 23 |
| » Defeated Phillies (3-10), 9-2 | Veteran's Stadium (1-0) | 12-3 | Won 11 |
| » W: Bob Forsch (3-0) L: Mike Krukow (1-2) | First | -- |
| » Major-league debuts: Julio Franco (Phillies) |
| Saturday, April 24 |
| » Defeated Phillies (3-11), 7-4 | Veteran's Stadium (2-0) | 13-3 | Won 12 |
| » W: Doug Bair (1-0) L: Ed Farmer (0-1) S: Bruce Sutter (6) | First | -- |
| Sunday, April 25 |
| » Lost to Phillies (4-11), 8-4 | Veteran's Stadium (2-1) | 13-4 | |
| » W: Steve Carlton (1-4) L: Andy Rincon (1-1) S: Ed Farmer (2) | First | -- |
| Monday, April 26 |
| » Lost to Astros (7-12), 6-2 | Busch Stadium II (5-2) | 13-5 | Lost 2 |
| » W: Nolan Ryan (1-4) L: John Martin (2-2) | First | -- |
| Tuesday, April 27 |
| » Lost to Astros (8-12), 3-0 | Busch Stadium II (5-3) | 13-6 | Lost 3 |
| » W: Vern Ruhle (1-2) L: Steve Mura (2-1) S: Joe Sambito (4) | First | -- |
| Wednesday, April 28 |
| » Defeated Astros (8-13), 5-4 | Busch Stadium II (6-3) | 14-6 | |
| » W: Bob Forsch (4-0) L: Dave Smith (0-2) S: Bruce Sutter (7) | First | -- |
| Friday, April 30 |
| » Lost to Reds (8-12), 8-2 | Riverfront Stadium (0-1) | 14-7 | |
| » W: Frank Pastore (3-1) L: Joaquin Andujar (2-2) | First | -- |
| Former Cardinal Leo Dickerman dies in Atkins, AR at the age of 86. |
| Saturday, May 1 |
| » Lost to Reds (9-12), 10-1 | Riverfront Stadium (0-2) | 14-8 | Lost 2 |
| » W: Mario Soto (1-2) L: Andy Rincon (1-2) | First | -- |
| Sunday, May 2 |
| » Lost to Reds (10-12), 5-1 | Riverfront Stadium (0-3) | 14-9 | Lost 3 |
| » W: Charlie Leibrandt (1-1) L: Steve Mura (2-2) | First | -- |
| » Defeated Reds (10-13), 6-4 | Riverfront Stadium (1-3) | 15-9 | |
| » W: John Martin (3-2) L: Joe Price (0-1) S: Bruce Sutter (8) | First | -- |
| Monday, May 3 |
| » Defeated Cubs (8-16), 9-4 | Busch Stadium II (7-3) | 16-9 | Won 2 |
| » W: Doug Bair (2-0) L: Dickie Noles (3-3) | First | -- |
| Tuesday, May 4 |
| » Defeated Cubs (8-17), 7-4 | Busch Stadium II (8-3) | 17-9 | Won 3 |
| » W: Joaquin Andujar (3-2) L: Fergie Jenkins (2-3) S: Bruce Sutter (9) | First | -- |
| Wednesday, May 5 |
| » Defeated Cubs (8-18), 7-6 | Busch Stadium II (9-3) | 18-9 | Won 4 |
| » W: Doug Bair (3-0) L: Willie Hernandez (0-2) S: Bruce Sutter (10) | First | -- |
| Friday, May 7 |
| » Lost to Braves (19-8), 6-3 | Busch Stadium II (9-4) | 18-10 | |
| » W: Gene Garber (3-1) L: John Martin (3-3) | First | -- |
| Saturday, May 8 |
| » Defeated Braves (19-9), 8-7 | Busch Stadium II (10-4) | 19-10 | |
| » W: Bruce Sutter (1-0) L: Rick Camp (3-2) | First | -- |
| Sunday, May 9 |
| » Lost to Braves (20-9), 3-0 | Busch Stadium II (10-5) | 19-11 | |
| » W: Preston Hanna (2-0) L: Joaquin Andujar (3-3) S: Gene Garber (6) | First | -- |
| Monday, May 10 |
| » Lost to Reds (13-16), 3-1 | Busch Stadium II (10-6) | 19-12 | Lost 2 |
| » W: Frank Pastore (4-2) L: John Martin (3-4) S: Tom Hume (7) | First | -- |
| » Major-league debuts: Willie McGee (Cardinals) |
| Tuesday, May 11 |
| » Defeated Reds (13-17), 5-1 | Busch Stadium II (11-6) | 20-12 | |
| » W: Steve Mura (3-2) L: Mario Soto (2-3) S: Doug Bair (1) | First | -- |
| Thursday, May 13 |
| » Defeated Braves (21-11), 10-9 | Atlanta-Fulton County Stadium (1-0) | 21-12 | Won 2 |
| » W: Andy Rincon (2-2) L: Ken Dayley (0-1) S: Bruce Sutter (11) | First | -- |
| » Major-league debuts: Ken Dayley (Braves) |
| Friday, May 14 |
| » Lost to Braves (22-11), 2-1 | Atlanta-Fulton County Stadium (1-1) | 21-13 | |
| » W: Gene Garber (4-1) L: Doug Bair (3-1) | First | -- |
| Saturday, May 15 |
| » Defeated Braves (22-12), 7-6 | Atlanta-Fulton County Stadium (2-1) | 22-13 | |
| » W: Bruce Sutter (2-0) L: Gene Garber (4-2) S: Bob Forsch (1) | First | -- |
| Sunday, May 16 |
| » Lost to Braves (23-12), 5-2 | Atlanta-Fulton County Stadium (2-2) | 22-14 | |
| » W: Rick Mahler (3-3) L: Steve Mura (3-3) | First | -- |
| Tuesday, May 18 |
| » Defeated Padres (18-16), 2-0 | San Diego/Jack Murphy Stadium (1-0) | 23-14 | |
| » W: Bob Forsch (5-0) L: John Curtis (2-2) | First | -- |
| Wednesday, May 19 |
| » Lost to Padres (19-16), 5-4 | San Diego/Jack Murphy Stadium (1-1) | 23-15 | |
| » W: Danny Boone (1-0) L: Bruce Sutter (2-1) | First | -- |
| Thursday, May 20 |
| » Defeated Padres (19-17), 6-3 | San Diego/Jack Murphy Stadium (2-1) | 24-15 | |
| » W: Dave LaPoint (2-0) L: Chris Welsh (1-1) | First | -- |
| Friday, May 21 |
| » Defeated Dodgers (19-21), 6-3 | Dodger Stadium (1-0) | 25-15 | Won 2 |
| » W: Steve Mura (4-3) L: Jerry Reuss (4-4) S: Bruce Sutter (12) | First | -- |
| Saturday, May 22 |
| » Lost to Dodgers (20-21), 3-2 | Dodger Stadium (1-1) | 25-16 | |
| » W: Ted Power (1-1) L: Andy Rincon (2-3) S: Tom Niedenfuer (5) | First | -- |
| Sunday, May 23 |
| » Lost to Dodgers (21-21), 5-0 | Dodger Stadium (1-2) | 25-17 | Lost 2 |
| » W: Bob Welch (5-2) L: Bob Forsch (5-1) | First | -- |
| Monday, May 24 |
| » Defeated Giants (19-25), 6-0 | Candlestick Park (1-0) | 26-17 | |
| » W: Joaquin Andujar (4-3) L: Rich Gale (1-4) | First | -- |
| Tuesday, May 25 |
| » Defeated Giants (19-26), 8-3 | Candlestick Park (2-0) | 27-17 | Won 2 |
| » W: Dave LaPoint (3-0) L: Renie Martin (0-2) | First | -- |
| Wednesday, May 26 |
| » Defeated Giants (19-27), 8-4 | Candlestick Park (3-0) | 28-17 | Won 3 |
| » W: Steve Mura (5-3) L: Atlee Hammaker (2-3) S: Bruce Sutter (13) | First | -- |
| Friday, May 28 |
| » Defeated Padres (23-20), 5-2 | Busch Stadium II (12-6) | 29-17 | Won 4 |
| » W: Bob Forsch (6-1) L: Juan Eichelberger (4-6) S: Bruce Sutter (14) | First | -- |
| Saturday, May 29 |
| » Lost to Padres (24-20), 4-2 | Busch Stadium II (12-7) | 29-18 | |
| » W: John Curtis (3-3) L: Joaquin Andujar (4-4) S: Eric Show (1) | First | -- |
| Sunday, May 30 |
| » Defeated Padres (24-21), 6-5 | Busch Stadium II (13-7) | 30-18 | |
| » W: Bruce Sutter (3-1) L: Gary Lucas (0-4) | First | -- |
| Monday, May 31 |
| » Defeated Giants (21-29), 11-6 | Busch Stadium II (14-7) | 31-18 | Won 2 |
| » W: John Martin (4-4) L: Renie Martin (0-3) | First | -- |
| Tuesday, June 1 |
| » Lost to Giants (22-29), 4-3 | Busch Stadium II (14-8) | 31-19 | |
| » W: Greg Minton (3-3) L: Jim Kaat (1-1) S: Gary Lavelle (2) | First | -- |
| » Major-league debuts: John Stuper (Cardinals) |
| Wednesday, June 2 |
| » Defeated Giants (22-30), 1-0 | Busch Stadium II (15-8) | 32-19 | |
| » W: Joaquin Andujar (5-4) L: Bill Laskey (4-3) | First | -- |
| Friday, June 4 |
| » Defeated Dodgers (25-27), 5-2 | Busch Stadium II (16-8) | 33-19 | Won 2 |
| » W: Bob Forsch (7-1) L: Dave Stewart (1-3) | First | -- |
| Former Cardinal Tony Kaufmann dies in Elgin, IL at the age of 82. |
| Saturday, June 5 |
| » Lost to Dodgers (26-27), 6-2 | Busch Stadium II (16-9) | 33-20 | |
| » W: Fernando Valenzuela (8-4) L: Steve Mura (5-4) | First | -- |
| Sunday, June 6 |
| » Lost to Dodgers (27-27), 5-3 | Busch Stadium II (16-10) | 33-21 | Lost 2 |
| » W: Steve Howe (4-1) L: Bruce Sutter (3-2) S: Terry Forster (3) | First | -- |
| Monday, June 7 |
| » Lost to Expos (27-23), 3-2 | Stade Olympique (0-1) | 33-22 | Lost 3 |
| » W: Ray Burris (1-7) L: Bruce Sutter (3-3) | First | -- |
| Tuesday, June 8 |
| » Defeated Expos (27-24), 5-4 | Stade Olympique (1-1) | 34-22 | |
| » W: Bruce Sutter (4-3) L: Woodie Fryman (2-2) | First | -- |
| Wednesday, June 9 |
| » Lost to Expos (28-24), 5-1 | Stade Olympique (1-2) | 34-23 | |
| » W: Bill Gullickson (4-5) L: Bob Forsch (7-2) S: Jeff Reardon (8) | First | -- |
| Friday, June 11 |
| » Defeated Mets (29-28), 7-3 | Shea Stadium (1-0) | 35-23 | |
| » W: Joaquin Andujar (6-4) L: Randy Jones (6-5) | First | -- |
| Saturday, June 12 |
| » Lost to Mets (30-28), 6-2 | Shea Stadium (1-1) | 35-24 | |
| » W: Craig Swan (5-1) L: Steve Mura (5-5) | First | -- |
| Monday, June 14 |
| » Defeated Expos (31-25), 2-1 | Busch Stadium II (17-10) | 36-24 | |
| » W: Bob Forsch (8-2) L: Bill Gullickson (4-6) S: Bruce Sutter (15) | First | -- |
| Tuesday, June 15 |
| » Defeated Expos (31-26), 3-2 | Busch Stadium II (18-10) | 37-24 | Won 2 |
| » W: Bruce Sutter (5-3) L: Ray Burris (2-8) | First | -- |
| Wednesday, June 16 |
| » Lost to Expos (32-26), 8-3 | Busch Stadium II (18-11) | 37-25 | |
| » W: Charlie Lea (5-2) L: Dave LaPoint (3-1) | First | -- |
| Friday, June 18 |
| » Lost to Mets (32-29), 5-3 | Busch Stadium II (18-12) | 37-26 | Lost 2 |
| » W: Jesse Orosco (1-5) L: Bruce Sutter (5-4) S: Mike Scott (1) | First | -- |
| » Defeated Mets (32-30), 5-4 | Busch Stadium II (19-12) | 38-26 | |
| » W: John Stuper (1-0) L: Ed Lynch (1-3) S: Doug Bair (2) | First | -- |
| Saturday, June 19 |
| » Lost to Mets (33-30), 8-5 | Busch Stadium II (19-13) | 38-27 | |
| » W: Tom Hausman (1-0) L: Jeff Keener (0-1) S: Mike Scott (2) | First | -- |
| Sunday, June 20 |
| » Lost to Mets (34-30), 5-4 | Busch Stadium II (19-14) | 38-28 | Lost 2 |
| » W: Mike Scott (5-5) L: Bruce Sutter (5-5) S: Ed Lynch (2) | First | -- |
| Monday, June 21 |
| » Defeated Phillies (33-31), 7-5 | Busch Stadium II (20-14) | 39-28 | |
| » W: Bruce Sutter (6-5) L: Ron Reed (2-2) | First | -- |
| Tuesday, June 22 |
| » Defeated Phillies (33-32), 3-2 | Busch Stadium II (21-14) | 40-28 | Won 2 |
| » W: John Stuper (2-0) L: Sparky Lyle (2-2) | First | -- |
| Wednesday, June 23 |
| » Lost to Phillies (34-32), 7-1 | Busch Stadium II (21-15) | 40-29 | |
| » W: Mike Krukow (6-5) L: Steve Mura (5-6) | Second | 2 out |
| Thursday, June 24 |
| » Lost to Phillies (35-32), 10-2 | Busch Stadium II (21-16) | 40-30 | Lost 2 |
| » W: Steve Carlton (9-7) L: Bob Forsch (8-3) | Second | 2 out |
| Friday, June 25 |
| » Lost to Cubs (27-44), 5-3 | Wrigley Field (3-1) | 40-31 | Lost 3 |
| » W: Fergie Jenkins (5-8) L: Joaquin Andujar (6-5) | First | -- |
| Saturday, June 26 |
| » Defeated Cubs (27-45), 4-1 | Wrigley Field (4-1) | 41-31 | |
| » W: Dave LaPoint (4-1) L: Doug Bird (4-8) S: Bruce Sutter (16) | First | -- |
| » Defeated Cubs (27-46), 2-1 | Wrigley Field (5-1) | 42-31 | Won 2 |
| » W: Jim Kaat (2-1) L: Lee Smith (1-3) S: Bruce Sutter (17) | First | -- |
| Sunday, June 27 |
| » Lost to Cubs (28-46), 4-2 | Wrigley Field (5-2) | 42-32 | |
| » W: Allen Ripley (3-0) L: John Stuper (2-1) S: Bill Campbell (6) | First | -- |
| » Major-league debuts: Jeff Lahti (Cardinals) |
| Former Cardinal Eddie Morgan dies in Lakewood, OH at the age of 68. |
| Monday, June 28 |
| » Lost to Phillies (41-32), 1-0 | Veteran's Stadium (2-2) | 42-33 | Lost 2 |
| » W: Steve Carlton (10-7) L: Steve Mura (5-7) | Second | 1 out |
| Tuesday, June 29 |
| » Defeated Phillies (41-33), 15-3 | Veteran's Stadium (3-2) | 43-33 | |
| » W: Joaquin Andujar (7-5) L: Dick Ruthven (6-6) | First | -- |
| Wednesday, June 30 |
| » Lost to Phillies (42-33), 6-3 | Veteran's Stadium (3-3) | 43-34 | |
| » W: Larry Christenson (4-4) L: Bob Forsch (8-4) S: Tug McGraw (2) | Second | 1 out |
| Friday, July 2 |
| » Lost to Cubs (30-49), 4-3 | Busch Stadium II (21-17) | 43-35 | Lost 2 |
| » W: Ken Kravec (1-0) L: Dave LaPoint (4-2) S: Dick Tidrow (1) | Second | 1 out |
| Saturday, July 3 |
| » Lost to Cubs (31-49), 2-1 | Busch Stadium II (21-18) | 43-36 | Lost 3 |
| » W: Tom Filer (1-2) L: Joaquin Andujar (7-6) S: Willie Hernandez (6) | Second | 1½ out |
| Sunday, July 4 |
| » Defeated Cubs (31-50), 7-2 | Busch Stadium II (22-18) | 44-36 | |
| » W: John Stuper (3-1) L: Dickie Noles (5-7) S: Bruce Sutter (18) | Second | 1 out |
| Monday, July 5 |
| » Defeated Reds (31-48), 6-5 | Riverfront Stadium (2-3) | 45-36 | Won 2 |
| » W: Jim Kaat (3-1) L: Tom Hume (1-4) S: Doug Bair (3) | Second | 1 out |
| Tuesday, July 6 |
| » Defeated Reds (31-49), 3-1 | Riverfront Stadium (3-3) | 46-36 | Won 3 |
| » W: Steve Mura (6-7) L: Charlie Leibrandt (3-4) | Second | 1 out |
| Wednesday, July 7 |
| » Lost to Braves (50-30), 3-2 | Atlanta-Fulton County Stadium (2-3) | 46-37 | |
| » W: Rick Camp (6-3) L: Joaquin Andujar (7-7) S: Gene Garber (16) | Second | 1 out |
| Thursday, July 8 |
| » Defeated Braves (50-31), 5-2 | Atlanta-Fulton County Stadium (3-3) | 47-37 | |
| » W: John Stuper (4-1) L: Rick Mahler (8-7) S: Doug Bair (4) | First | -- |
| Friday, July 9 |
| » Defeated Astros (35-48), 3-2 | Astrodome (2-2) | 48-37 | Won 2 |
| » W: Dave LaPoint (5-2) L: Nolan Ryan (8-9) S: Jim Kaat (1) | First | -- |
| Saturday, July 10 |
| » Lost to Astros (36-48), 4-2 | Astrodome (2-3) | 48-38 | |
| » W: Joe Niekro (8-6) L: Bob Forsch (8-5) | First | -- |
| Sunday, July 11 |
| » Lost to Astros (37-48), 4-2 | Astrodome (2-4) | 48-39 | Lost 2 |
| » W: Bob Knepper (3-10) L: Joaquin Andujar (7-8) | Second | 1 out |
| Tuesday, July 13 |
| Future Cardinal Yadier Molina is born in Bayamon, P.R. |
| Thursday, July 15 |
| » Lost to Reds (34-53), 7-3 | Busch Stadium II (22-19) | 48-40 | Lost 3 |
| » W: Bruce Berenyi (6-9) L: John Stuper (4-2) S: Jim Kern (2) | Second | 1 out |
| » Major-league debuts: Tom Lawless (Reds) |
| Friday, July 16 |
| » Defeated Reds (34-54), 6-4 | Busch Stadium II (23-19) | 49-40 | |
| » W: Jeff Lahti (1-0) L: Tom Hume (2-5) S: Bruce Sutter (19) | Second | 1 out |
| Saturday, July 17 |
| » Defeated Reds (34-55), 4-2 | Busch Stadium II (24-19) | 50-40 | Won 2 |
| » W: Bob Forsch (9-5) L: Mario Soto (8-6) S: Doug Bair (5) | Second | 1 out |
| Sunday, July 18 |
| » Defeated Reds (34-56), 6-5 | Busch Stadium II (25-19) | 51-40 | Won 3 |
| » W: Jim Kaat (4-1) L: Charlie Leibrandt (3-5) S: Bruce Sutter (20) | Second | 1 out |
| Monday, July 19 |
| » Lost to Braves (55-34), 4-1 | Busch Stadium II (25-20) | 51-41 | |
| » W: Phil Niekro (8-3) L: Joaquin Andujar (7-9) S: Gene Garber (17) | Second | 1 out |
| Tuesday, July 20 |
| » Lost to Braves (56-34), 8-6 | Busch Stadium II (25-21) | 51-42 | Lost 2 |
| » W: Joe Cowley (1-1) L: Jeff Lahti (1-1) S: Steve Bedrosian (6) | Second | 1 out |
| Wednesday, July 21 |
| » Defeated Braves (56-35), 8-0 | Busch Stadium II (26-21) | 52-42 | |
| » W: Steve Mura (7-7) L: Bob Walk (8-7) | Second | 1 out |
| Friday, July 23 |
| » Defeated Astros (41-52), 6-2 | Busch Stadium II (27-21) | 53-42 | Won 2 |
| » W: Joaquin Andujar (8-9) L: Joe Niekro (9-7) | Second | 1 out |
| Saturday, July 24 |
| » Defeated Astros (41-53), 5-1 | Busch Stadium II (28-21) | 54-42 | Won 3 |
| » W: Bob Forsch (10-5) L: Bob Knepper (4-11) | Second | 1 out |
| Sunday, July 25 |
| » Defeated Astros (41-54), 4-3 | Busch Stadium II (29-21) | 55-42 | Won 4 |
| » W: Bruce Sutter (7-5) L: Don Sutton (9-7) | Second | 1 out |
| Tuesday, July 27 |
| » Defeated Mets (44-53), 9-4 | Busch Stadium II (30-21) | 56-42 | Won 5 |
| » W: Jeff Lahti (2-1) L: Mike Scott (7-8) S: Doug Bair (6) | First | -- |
| Wednesday, July 28 |
| » Defeated Mets (44-54), 7-5 | Busch Stadium II (31-21) | 57-42 | Won 6 |
| » W: Jeff Keener (1-1) L: Ed Lynch (1-4) S: Bruce Sutter (21) | First | -- |
| Thursday, July 29 |
| » Lost to Expos (52-46), 4-3 | Stade Olympique (1-3) | 57-43 | |
| » W: Woodie Fryman (5-2) L: Doug Bair (3-2) | Second | 1 out |
| » Major-league debuts: Bryan Little (Expos) |
| Friday, July 30 |
| » Lost to Expos (53-46), 5-4 | Stade Olympique (1-4) | 57-44 | Lost 2 |
| » W: Woodie Fryman (6-2) L: Doug Bair (3-3) | Second | 1 out |
| Saturday, July 31 |
| » Defeated Expos (53-47), 10-1 | Stade Olympique (2-4) | 58-44 | |
| » W: Steve Mura (8-7) L: Ray Burris (4-12) | Second | 1 out |
| Sunday, August 1 |
| » Lost to Expos (54-47), 5-4 | Stade Olympique (2-5) | 58-45 | |
| » W: Jeff Reardon (4-1) L: Jeff Lahti (2-2) S: Woodie Fryman (7) | Second | 1 out |
| Monday, August 2 |
| » Lost to Pirates (55-46), 4-2 | Busch Stadium II (31-22) | 58-46 | Lost 2 |
| » W: Enrique Romo (6-2) L: Jim Kaat (4-2) | Second | 2 out |
| Tuesday, August 3 |
| » Defeated Pirates (55-47), 4-2 | Busch Stadium II (32-22) | 59-46 | |
| » W: Bob Forsch (11-5) L: Don Robinson (11-6) S: Bruce Sutter (22) | Second | 2 out |
| Wednesday, August 4 |
| » Lost to Pirates (56-47), 5-2 | Busch Stadium II (32-23) | 59-47 | |
| » W: John Candelaria (9-4) L: Dave LaPoint (5-3) S: Rod Scurry (9) | Second | 3 out |
| Thursday, August 5 |
| » Defeated Pirates (56-48), 7-3 | Busch Stadium II (33-23) | 60-47 | |
| » W: Steve Mura (9-7) L: Larry McWilliams (7-5) | Second | 2 out |
| Friday, August 6 |
| » Lost to Expos (56-50), 5-3 | Busch Stadium II (33-24) | 60-48 | |
| » W: Steve Rogers (14-4) L: Joaquin Andujar (8-10) S: Jeff Reardon (16) | Second | 2 out |
| Saturday, August 7 |
| » Defeated Expos (56-51), 9-5 | Busch Stadium II (34-24) | 61-48 | |
| » W: Jim Kaat (5-2) L: Dan Schatzeder (1-6) | Second | 1 out |
| Sunday, August 8 |
| » Lost to Expos (57-51), 2-1 | Busch Stadium II (34-25) | 61-49 | |
| » W: David Palmer (6-4) L: Bob Forsch (11-6) S: Woodie Fryman (8) | Second | 1 out |
| Monday, August 9 |
| » Defeated Mets (48-62), 7-2 | Shea Stadium (2-1) | 62-49 | |
| » W: Jeff Lahti (3-2) L: Charlie Puleo (8-9) | Second | 1 out |
| Tuesday, August 10 |
| » Defeated Mets (48-63), 7-2 | Shea Stadium (3-1) | 63-49 | Won 2 |
| » W: Steve Mura (10-7) L: Randy Jones (7-9) | Second | ½ out |
| Thursday, August 12 |
| » Defeated Pirates (59-54), 3-2 | Three Rivers Stadium (3-0) | 64-49 | Won 3 |
| » W: Joaquin Andujar (9-10) L: Ross Baumgarten (0-4) S: Bruce Sutter (23) | First | -- |
| Friday, August 13 |
| » Lost to Pirates (60-54), 7-4 | Three Rivers Stadium (3-1) | 64-50 | |
| » W: Don Robinson (13-6) L: Bob Forsch (11-7) | First | -- |
| Saturday, August 14 |
| » Defeated Pirates (60-55), 4-1 | Three Rivers Stadium (4-1) | 65-50 | |
| » W: John Stuper (5-2) L: John Candelaria (9-5) S: Bruce Sutter (24) | First | -- |
| Sunday, August 15 |
| » Defeated Pirates (60-56), 12-5 | Three Rivers Stadium (5-1) | 66-50 | Won 2 |
| » W: Steve Mura (11-7) L: Larry McWilliams (7-6) | First | -- |
| » Defeated Pirates (60-57), 5-2 | Three Rivers Stadium (6-1) | 67-50 | Won 3 |
| » W: Dave LaPoint (6-3) L: Manny Sarmiento (5-3) | First | -- |
| Tuesday, August 17 |
| » Defeated Padres (63-56), 3-2 | Busch Stadium II (35-25) | 68-50 | Won 4 |
| » W: Bruce Sutter (8-5) L: Gary Lucas (0-9) | First | -- |
| Wednesday, August 18 |
| » Defeated Padres (63-57), 2-1 | Busch Stadium II (36-25) | 69-50 | Won 5 |
| » W: Bob Forsch (12-7) L: Andy Hawkins (2-3) S: Bruce Sutter (25) | First | -- |
| Thursday, August 19 |
| » Lost to Padres (64-57), 4-3 | Busch Stadium II (36-26) | 69-51 | |
| » W: Dave Dravecky (4-1) L: John Stuper (5-3) S: Luis DeLeon (11) | First | -- |
| Friday, August 20 |
| » Lost to Giants (64-59), 8-7 | Busch Stadium II (36-27) | 69-52 | Lost 2 |
| » W: Gary Lavelle (8-5) L: Bruce Sutter (8-6) S: Greg Minton (22) | First | -- |
| Saturday, August 21 |
| » Defeated Giants (64-60), 7-6 | Busch Stadium II (37-27) | 70-52 | |
| » W: Dave LaPoint (7-3) L: Bill Laskey (12-9) S: Bruce Sutter (26) | First | -- |
| Sunday, August 22 |
| » Defeated Giants (64-61), 5-4 | Busch Stadium II (38-27) | 71-52 | Won 2 |
| » W: Jeff Lahti (4-2) L: Gary Lavelle (8-6) | First | -- |
| Monday, August 23 |
| » Defeated Dodgers (69-57), 11-3 | Busch Stadium II (39-27) | 72-52 | Won 3 |
| » W: Bob Forsch (13-7) L: Jerry Reuss (12-10) S: Bruce Sutter (27) | First | -- |
| Tuesday, August 24 |
| » Lost to Dodgers (70-57), 5-2 | Busch Stadium II (39-28) | 72-53 | |
| » W: Bob Welch (15-8) L: John Stuper (5-4) | First | -- |
| Wednesday, August 25 |
| » Lost to Dodgers (71-57), 11-3 | Busch Stadium II (39-29) | 72-54 | Lost 2 |
| » W: Fernando Valenzuela (17-9) L: Steve Mura (11-8) | First | -- |
| Friday, August 27 |
| » Defeated Padres (66-63), 2-1 | San Diego/Jack Murphy Stadium (3-1) | 73-54 | |
| » W: Joaquin Andujar (10-10) L: Tim Lollar (12-8) S: Bruce Sutter (28) | First | -- |
| Sunday, August 29 |
| » Lost to Padres (67-63), 9-4 | San Diego/Jack Murphy Stadium (3-2) | 73-55 | |
| » W: John Curtis (8-6) L: Bob Forsch (13-8) | First | -- |
| » Defeated Padres (67-64), 5-3 | San Diego/Jack Murphy Stadium (4-2) | 74-55 | |
| » W: Doug Bair (4-3) L: Andy Hawkins (2-5) S: Bruce Sutter (29) | First | -- |
| Monday, August 30 |
| » Defeated Dodgers (73-59), 3-2 | Dodger Stadium (2-2) | 75-55 | Won 2 |
| » W: John Stuper (6-4) L: Fernando Valenzuela (17-10) S: Bruce Sutter (30) | First | -- |
| Tuesday, August 31 |
| » Lost to Dodgers (74-59), 4-1 | Dodger Stadium (2-3) | 75-56 | |
| » W: Burt Hooton (2-5) L: Steve Mura (11-9) S: Steve Howe (12) | First | -- |
| Wednesday, September 1 |
| » Defeated Dodgers (74-60), 6-5 | Dodger Stadium (3-3) | 76-56 | |
| » W: Doug Bair (5-3) L: Ricky Wright (2-1) S: Jim Kaat (2) | First | -- |
| » Major-league debuts: Greg Brock and Dave Sax (Dodgers) |
| Friday, September 3 |
| » Lost to Giants (67-67), 3-2 | Candlestick Park (3-1) | 76-57 | |
| » W: Greg Minton (9-4) L: Bruce Sutter (8-7) | First | -- |
| Saturday, September 4 |
| » Lost to Giants (68-67), 5-4 | Candlestick Park (3-2) | 76-58 | Lost 2 |
| » W: Gary Lavelle (9-6) L: Bruce Sutter (8-8) | First | -- |
| » Major-league debuts: Brad Wellman (Giants) |
| Sunday, September 5 |
| » Lost to Giants (69-67), 5-1 | Candlestick Park (3-3) | 76-59 | Lost 3 |
| » W: Fred Breining (8-4) L: John Stuper (6-5) | First | -- |
| Monday, September 6 |
| » Defeated Expos (73-64), 1-0 | Busch Stadium II (40-29) | 77-59 | |
| » W: Joaquin Andujar (11-10) L: Bill Gullickson (10-11) | First | -- |
| Tuesday, September 7 |
| » Lost to Expos (74-64), 7-4 | Busch Stadium II (40-30) | 77-60 | |
| » W: Bryn Smith (2-1) L: Jeff Lahti (4-3) S: Jeff Reardon (23) | First | -- |
| Former Cardinal Ken Boyer dies in St.Louis, MO at the age of 52. |
| Wednesday, September 8 |
| » Defeated Expos (74-65), 1-0 | Busch Stadium II (41-30) | 78-60 | |
| » W: Bob Forsch (14-8) L: Charlie Lea (11-9) | First | -- |
| Friday, September 10 |
| » Lost to Mets (55-83), 2-1 | Busch Stadium II (41-31) | 78-61 | |
| » W: Craig Swan (9-6) L: John Stuper (6-6) S: Jesse Orosco (3) | Second | ½ out |
| Saturday, September 11 |
| » Defeated Mets (55-84), 6-3 | Busch Stadium II (42-31) | 79-61 | |
| » W: Joaquin Andujar (12-10) L: Ed Lynch (3-7) S: Bruce Sutter (31) | First | -- |
| Sunday, September 12 |
| » Lost to Mets (56-84), 4-1 | Busch Stadium II (42-32) | 79-62 | |
| » W: Pete Falcone (8-9) L: Steve Mura (11-10) | First | -- |
| Monday, September 13 |
| » Lost to Phillies (80-63), 2-0 | Veteran's Stadium (3-4) | 79-63 | Lost 2 |
| » W: Steve Carlton (20-9) L: Bob Forsch (14-9) | Second | ½ out |
| Tuesday, September 14 |
| » Defeated Phillies (80-64), 2-0 | Veteran's Stadium (4-4) | 80-63 | |
| » W: John Stuper (7-6) L: Mike Krukow (12-10) S: Bruce Sutter (32) | First | -- |
| Wednesday, September 15 |
| » Defeated Phillies (80-65), 8-0 | Veteran's Stadium (5-4) | 81-63 | Won 2 |
| » W: Joaquin Andujar (13-10) L: John Denny (6-12) | First | -- |
| Friday, September 17 |
| » Defeated Mets (57-87), 3-2 | Shea Stadium (4-1) | 82-63 | Won 3 |
| » W: Bruce Sutter (9-8) L: Neil Allen (3-7) | First | -- |
| » Defeated Mets (57-88), 7-1 | Shea Stadium (5-1) | 83-63 | Won 4 |
| » W: Steve Mura (12-10) L: Scott Holman (0-1) S: Doug Bair (7) | First | -- |
| Saturday, September 18 |
| » Defeated Mets (57-89), 2-0 | Shea Stadium (6-1) | 84-63 | Won 5 |
| » W: Bob Forsch (15-9) L: Pete Falcone (8-10) S: Bruce Sutter (33) | First | -- |
| » Defeated Mets (57-90), 6-2 | Shea Stadium (7-1) | 85-63 | Won 6 |
| » W: Jeff Lahti (5-3) L: Walt Terrell (0-1) | First | -- |
| Sunday, September 19 |
| » Defeated Mets (57-91), 3-1 | Shea Stadium (8-1) | 86-63 | Won 7 |
| » W: John Stuper (8-6) L: Pat Zachry (6-8) S: Doug Bair (8) | First | -- |
| Monday, September 20 |
| » Defeated Phillies (81-68), 4-1 | Busch Stadium II (43-32) | 87-63 | Won 8 |
| » W: Joaquin Andujar (14-10) L: John Denny (6-13) S: Bruce Sutter (34) | First | -- |
| Tuesday, September 21 |
| » Lost to Phillies (82-68), 5-2 | Busch Stadium II (43-33) | 87-64 | |
| < |
