| Tuesday, April 6 |
| » Lost to Athletics (1-0), 3-2 | Oakland-Alameda County Stadium (0-1) | 0-1 | |
| » W: Jeff Jones (1-0) L: Don Aase (0-1) | Third | 1 out |
| Wednesday, April 7 |
| » Defeated Athletics (1-1), 7-0 | Oakland-Alameda County Stadium (1-1) | 1-1 | |
| » W: Geoff Zahn (1-0) L: Mike Norris (0-1) | Second | 1 out |
| Thursday, April 8 |
| » Defeated Athletics (1-2), 8-6 | Oakland-Alameda County Stadium (2-1) | 2-1 | Won 2 |
| » W: Luis Sanchez (1-0) L: Jeff Jones (1-1) | First | -- |
| Friday, April 9 |
| » Lost to Twins (3-1), 2-1 | Hubert H. Humphrey Metrodome (0-1) | 2-2 | |
| » W: Albert Williams (1-0) L: Angel Moreno (0-1) | Fourth | 1 out |
| Saturday, April 10 |
| » Defeated Twins (3-2), 8-1 | Hubert H. Humphrey Metrodome (1-1) | 3-2 | |
| » W: Steve Renko (1-0) L: Darrell Jackson (0-1) | Third | 2 out |
| Sunday, April 11 |
| » Lost to Twins (4-2), 3-1 | Hubert H. Humphrey Metrodome (1-2) | 3-3 | |
| » W: Pete Redfern (1-1) L: Ken Forsch (0-1) | Fifth | 2 out |
| Tuesday, April 13 |
| » Game at Anaheim Stadium interrupted in the 18th inning with the score of Mariners 3, Angels 3. Completed on April 14. |
| Wednesday, April 14 |
| » Defeated Mariners (2-5), 4-3 | Anaheim Stadium (1-0) | 4-3 | |
| » W: Luis Sanchez (2-0) L: Gene Nelson (0-2) | Third | 2 out |
| » Defeated Mariners (2-6), 2-1 | Anaheim Stadium (2-0) | 5-3 | Won 2 |
| » W: Steve Renko (2-0) L: Ed Vande Berg (0-1) | Third | 2 out |
| Thursday, April 15 |
| » Defeated Mariners (2-7), 3-2 | Anaheim Stadium (3-0) | 6-3 | Won 3 |
| » W: Angel Moreno (1-1) L: Gaylord Perry (0-2) | Second | 2 out |
| Friday, April 16 |
| » Defeated Twins (5-5), 4-2 | Anaheim Stadium (4-0) | 7-3 | Won 4 |
| » W: Don Aase (1-1) L: Doug Corbett (0-1) | Third | 2½ out |
| Saturday, April 17 |
| » Defeated Twins (5-6), 6-2 | Anaheim Stadium (5-0) | 8-3 | Won 5 |
| » W: Ken Forsch (1-1) L: Terry Felton (0-1) | Third | 2 out |
| Sunday, April 18 |
| » Defeated Twins (5-7), 5-2 | Anaheim Stadium (6-0) | 9-3 | Won 6 |
| » W: Geoff Zahn (2-0) L: Roger Erickson (1-2) | Second | 2 out |
| Monday, April 19 |
| » Defeated Mariners (4-9), 3-1 | Kingdome (1-0) | 10-3 | Won 7 |
| » W: Mike Witt (1-0) L: Gene Nelson (0-3) S: Don Aase (1) | Second | 2½ out |
| Tuesday, April 20 |
| » Lost to Mariners (5-9), 6-4 | Kingdome (1-1) | 10-4 | |
| » W: Gaylord Perry (1-2) L: Angel Moreno (1-2) S: Mike Stanton (2) | Second | 2½ out |
| Wednesday, April 21 |
| » Lost to Mariners (6-9), 5-3 | Kingdome (1-2) | 10-5 | Lost 2 |
| » W: Floyd Bannister (3-0) L: Steve Renko (2-1) S: Bill Caudill (1) | Second | 2½ out |
| Friday, April 23 |
| » Defeated Athletics (8-8), 7-2 | Anaheim Stadium (7-0) | 11-5 | |
| » W: Ken Forsch (2-1) L: Matt Keough (2-1) | Second | 2½ out |
| Saturday, April 24 |
| » Defeated Athletics (8-9), 4-2 | Anaheim Stadium (8-0) | 12-5 | Won 2 |
| » W: Geoff Zahn (3-0) L: Steve McCatty (1-1) S: Don Aase (2) | Second | 2½ out |
| Sunday, April 25 |
| » Defeated Athletics (8-10), 5-1 | Anaheim Stadium (9-0) | 13-5 | Won 3 |
| » W: Mike Witt (2-0) L: Rick Langford (1-3) | First | -- |
| Tuesday, April 27 |
| » Defeated Yankees (6-9), 3-1 | Yankee Stadium (1-0) | 14-5 | Won 4 |
| » W: Angel Moreno (2-2) L: Ron Guidry (2-1) | First | -- |
| Wednesday, April 28 |
| » Lost to Yankees (7-9), 6-0 | Yankee Stadium (1-1) | 14-6 | |
| » W: Tommy John (1-3) L: Ken Forsch (2-2) | First | -- |
| Thursday, April 29 |
| » Defeated Yankees (7-10), 2-0 | Yankee Stadium (2-1) | 15-6 | |
| » W: Geoff Zahn (4-0) L: Shane Rawley (1-1) | First | -- |
| Friday, April 30 |
| » Lost to Orioles (6-12), 9-4 | Memorial Stadium (0-1) | 15-7 | |
| » W: Jim Palmer (1-1) L: Stan Bahnsen (0-1) | First | -- |
| Saturday, May 1 |
| » Defeated Orioles (6-13), 6-4 | Memorial Stadium (1-1) | 16-7 | |
| » W: Don Aase (2-1) L: Tippy Martinez (0-3) | First | -- |
| Sunday, May 2 |
| » Lost to Orioles (7-13), 6-4 | Memorial Stadium (1-2) | 16-8 | |
| » W: Scott McGregor (2-2) L: Angel Moreno (2-3) | First | -- |
| Monday, May 3 |
| » Defeated Indians (8-13), 5-4 | Cleveland Stadium (1-0) | 17-8 | |
| » W: Don Aase (3-1) L: Dan Spillner (0-2) | First | -- |
| Tuesday, May 4 |
| » Lost to Indians (9-13), 6-5 | Cleveland Stadium (1-1) | 17-9 | |
| » W: Lary Sorensen (2-1) L: Geoff Zahn (4-1) S: Dan Spillner (2) | First | -- |
| Thursday, May 6 |
| » Lost to Orioles (9-14), 9-2 | Anaheim Stadium (9-1) | 17-10 | Lost 2 |
| » W: Ross Grimsley (1-0) L: Don Aase (3-2) | First | -- |
| Friday, May 7 |
| » Lost to Orioles (10-14), 5-3 | Anaheim Stadium (9-2) | 17-11 | Lost 3 |
| » W: Scott McGregor (3-2) L: Angel Moreno (2-4) S: Tippy Martinez (2) | Second | 2 out |
| Saturday, May 8 |
| » Defeated Orioles (10-15), 7-2 | Anaheim Stadium (10-2) | 18-11 | |
| » W: Steve Renko (3-1) L: Mike Flanagan (1-4) S: Don Aase (3) | Second | 2 out |
| Sunday, May 9 |
| » Defeated Orioles (10-16), 8-4 | Anaheim Stadium (11-2) | 19-11 | Won 2 |
| » W: Bruce Kison (1-0) L: Dennis Martinez (2-3) | Second | 2 out |
| Monday, May 10 |
| » Defeated Yankees (11-16), 2-1 | Anaheim Stadium (12-2) | 20-11 | Won 3 |
| » W: Geoff Zahn (5-1) L: Rudy May (0-1) | Second | 2 out |
| Tuesday, May 11 |
| » Lost to Yankees (12-16), 3-2 | Anaheim Stadium (12-3) | 20-12 | |
| » W: Dave Righetti (2-2) L: Ken Forsch (2-3) S: Rich Gossage (6) | Second | 2 out |
| Wednesday, May 12 |
| » Lost to Yankees (13-16), 6-5 | Anaheim Stadium (12-4) | 20-13 | Lost 2 |
| » W: Shane Rawley (2-1) L: Angel Moreno (2-5) S: Rich Gossage (7) | Second | 2 out |
| Thursday, May 13 |
| » Defeated Indians (14-16), 3-2 | Anaheim Stadium (13-4) | 21-13 | |
| » W: Andy Hassler (1-0) L: Dan Spillner (0-3) | Second | 2 out |
| Friday, May 14 |
| » Defeated Indians (14-17), 5-2 | Anaheim Stadium (14-4) | 22-13 | Won 2 |
| » W: Bruce Kison (2-0) L: Lary Sorensen (3-2) S: Doug Corbett (4) | Second | 2 out |
| Saturday, May 15 |
| » Defeated Indians (14-18), 9-6 | Anaheim Stadium (15-4) | 23-13 | Won 3 |
| » W: Mike Witt (3-0) L: Tom Brennan (0-1) S: Doug Corbett (5) | First | -- |
| Sunday, May 16 |
| » Defeated Indians (14-19), 3-0 | Anaheim Stadium (16-4) | 24-13 | Won 4 |
| » W: Ken Forsch (3-3) L: John Denny (2-4) | First | -- |
| Tuesday, May 18 |
| » Defeated Brewers (18-16), 4-1 | County Stadium (1-0) | 25-13 | Won 5 |
| » W: Steve Renko (4-1) L: Mike Caldwell (2-4) | First | -- |
| Wednesday, May 19 |
| » Defeated Brewers (18-17), 7-2 | County Stadium (2-0) | 26-13 | Won 6 |
| » W: Bruce Kison (3-0) L: Jim Slaton (3-1) | First | -- |
| Thursday, May 20 |
| » Lost to Brewers (19-17), 4-1 | County Stadium (2-1) | 26-14 | |
| » W: Moose Haas (2-1) L: Geoff Zahn (5-2) | Second | 2 out |
| Friday, May 21 |
| » Defeated Tigers (24-13), 9-7 | Tiger Stadium (1-0) | 27-14 | |
| » W: Ken Forsch (4-3) L: Pat Underwood (2-2) S: Doug Corbett (6) | Second | 2 out |
| Saturday, May 22 |
| » Lost to Tigers (25-13), 5-1 | Tiger Stadium (1-1) | 27-15 | |
| » W: Jack Morris (6-3) L: Angel Moreno (2-6) | Second | 2 out |
| Sunday, May 23 |
| » Defeated Tigers (25-14), 7-2 | Tiger Stadium (2-1) | 28-15 | |
| » W: Steve Renko (5-1) L: Dan Petry (4-3) | Second | 2 out |
| Tuesday, May 25 |
| » Defeated Red Sox (28-14), 10-2 | Fenway Park (1-0) | 29-15 | Won 2 |
| » W: Bruce Kison (4-0) L: John Tudor (4-2) | First | -- |
| Thursday, May 27 |
| » Lost to Brewers (21-21), 4-3 | Anaheim Stadium (16-5) | 29-16 | |
| » W: Pete Vuckovich (5-2) L: Ken Forsch (4-4) S: Rollie Fingers (10) | Second | 1½ out |
| Friday, May 28 |
| » Defeated Brewers (21-22), 6-5 | Anaheim Stadium (17-5) | 30-16 | |
| » W: Doug Corbett (1-2) L: Dwight Bernard (2-1) | First | -- |
| Saturday, May 29 |
| » Defeated Brewers (21-23), 5-4 | Anaheim Stadium (18-5) | 31-16 | Won 2 |
| » W: Luis Sanchez (3-0) L: Jamie Easterly (0-1) | First | -- |
| Sunday, May 30 |
| » Lost to Brewers (22-23), 7-3 | Anaheim Stadium (18-6) | 31-17 | |
| » W: Jim Slaton (4-1) L: Bruce Kison (4-1) S: Jamie Easterly (1) | First | -- |
| Monday, May 31 |
| » Lost to Tigers (29-17), 4-3 | Anaheim Stadium (18-7) | 31-18 | Lost 2 |
| » W: Elias Sosa (3-2) L: Doug Corbett (1-3) | First | -- |
| Tuesday, June 1 |
| » Lost to Tigers (30-17), 2-1 | Anaheim Stadium (18-8) | 31-19 | Lost 3 |
| » W: Dan Petry (5-3) L: Ken Forsch (4-5) S: Dave Tobik (1) | First | -- |
| Wednesday, June 2 |
| » Lost to Tigers (31-17), 5-4 | Anaheim Stadium (18-9) | 31-20 | Lost 4 |
| » W: Aurelio Lopez (1-0) L: Doug Corbett (1-4) S: Dave Tobik (2) | First | -- |
| Friday, June 4 |
| » Lost to Red Sox (31-19), 11-4 | Anaheim Stadium (18-10) | 31-21 | Lost 5 |
| » W: Mark Clear (4-1) L: Doug Corbett (1-5) | First | -- |
| Saturday, June 5 |
| » Lost to Red Sox (32-19), 7-2 | Anaheim Stadium (18-11) | 31-22 | Lost 6 |
| » W: John Tudor (5-3) L: Bruce Kison (4-2) | First | -- |
| Sunday, June 6 |
| » Lost to Red Sox (33-19), 5-1 | Anaheim Stadium (18-12) | 31-23 | Lost 7 |
| » W: Bob Ojeda (3-4) L: Ken Forsch (4-6) S: Mark Clear (10) | Second | 2 out |
| Tuesday, June 8 |
| » Defeated Blue Jays (25-30), 11-4 | Exhibition Stadium (1-0) | 32-23 | |
| » W: Geoff Zahn (6-2) L: Jim Gott (1-3) | Third | 1½ out |
| » Major-league debuts: Tom Filer (Blue Jays) |
| Wednesday, June 9 |
| » Lost to Blue Jays (26-30), 5-4 | Exhibition Stadium (1-1) | 32-24 | |
| » W: Joey McLaughlin (3-3) L: Doug Corbett (1-6) | Third | 1½ out |
| Thursday, June 10 |
| » Lost to White Sox (32-23), 7-6 | Comiskey Park I (0-1) | 32-25 | Lost 2 |
| » W: Salome Barojas (3-1) L: Dave Goltz (0-2) | Third | 1½ out |
| Friday, June 11 |
| » Defeated White Sox (32-24), 6-5 | Comiskey Park I (1-1) | 33-25 | |
| » W: Bruce Kison (5-2) L: Richard Dotson (2-7) S: Doug Corbett (7) | Third | 1½ out |
| Saturday, June 12 |
| » Defeated White Sox (32-25), 3-0 | Comiskey Park I (2-1) | 34-25 | Won 2 |
| » W: Ken Forsch (5-6) L: Steve Trout (4-5) | Second | 1½ out |
| Sunday, June 13 |
| » Defeated White Sox (32-26), 7-4 | Comiskey Park I (3-1) | 35-25 | Won 3 |
| » W: Geoff Zahn (7-2) L: Dennis Lamp (4-2) | First | -- |
| Tuesday, June 15 |
| » Lost to Blue Jays (28-33), 2-0 | Anaheim Stadium (18-13) | 35-26 | |
| » W: Jim Clancy (7-3) L: Mike Witt (3-1) | Second | 1 out |
| Wednesday, June 16 |
| » Defeated Blue Jays (28-34), 7-1 | Anaheim Stadium (19-13) | 36-26 | |
| » W: Steve Renko (6-1) L: Dave Stieb (5-7) | Second | 1 out |
| Thursday, June 17 |
| » Defeated Blue Jays (28-35), 10-8 | Anaheim Stadium (20-13) | 37-26 | Won 2 |
| » W: Bruce Kison (6-2) L: Luis Leal (5-4) S: Angel Moreno (1) | First | -- |
| Friday, June 18 |
| » Defeated White Sox (35-27), 7-2 | Anaheim Stadium (21-13) | 38-26 | Won 3 |
| » W: Angel Moreno (3-6) L: Dennis Lamp (4-3) | First | -- |
| Saturday, June 19 |
| » Lost to White Sox (36-27), 7-6 | Anaheim Stadium (21-14) | 38-27 | |
| » W: Richard Dotson (3-7) L: Geoff Zahn (7-3) S: Kevin Hickey (3) | First | -- |
| Sunday, June 20 |
| » Defeated White Sox (36-28), 3-1 | Anaheim Stadium (22-14) | 39-27 | |
| » W: Mike Witt (4-1) L: La Marr Hoyt (10-4) | First | -- |
| Monday, June 21 |
| » Defeated Rangers (23-37), 10-2 | Anaheim Stadium (23-14) | 40-27 | Won 2 |
| » W: Steve Renko (7-1) L: Charlie Hough (5-5) | First | -- |
| Tuesday, June 22 |
| » Lost to Rangers (24-37), 4-0 | Anaheim Stadium (23-15) | 40-28 | |
| » W: Rick Honeycutt (3-7) L: Bruce Kison (6-3) | First | -- |
| Wednesday, June 23 |
| » Defeated Rangers (24-38), 5-3 | Anaheim Stadium (24-15) | 41-28 | |
| » W: Ken Forsch (6-6) L: Doc Medich (5-6) S: Doug Corbett (8) | First | -- |
| Thursday, June 24 |
| » Defeated Royals (39-28), 7-2 | Anaheim Stadium (25-15) | 42-28 | Won 2 |
| » W: Geoff Zahn (8-3) L: Keith Creel (1-4) | First | -- |
| Friday, June 25 |
| » Lost to Royals (40-28), 8-6 | Anaheim Stadium (25-16) | 42-29 | |
| » W: Dan Quisenberry (4-2) L: Angel Moreno (3-7) | First | -- |
| Saturday, June 26 |
| » Defeated Royals (40-29), 6-5 | Anaheim Stadium (26-16) | 43-29 | |
| » W: Ken Forsch (7-6) L: Dan Quisenberry (4-3) | First | -- |
| Sunday, June 27 |
| » Defeated Royals (40-30), 9-1 | Anaheim Stadium (27-16) | 44-29 | Won 2 |
| » W: Dave Goltz (1-2) L: Bud Black (2-2) | First | -- |
| Monday, June 28 |
| » Major-league debuts: Steve Hammond (Royals) |
| Tuesday, June 29 |
| » Defeated Rangers (27-40), 2-1 | Arlington Stadium (1-0) | 45-29 | Won 3 |
| » W: Geoff Zahn (9-3) L: Doc Medich (5-7) S: Doug Corbett (9) | First | -- |
| Wednesday, June 30 |
| » Lost to Rangers (28-40), 5-3 | Arlington Stadium (1-1) | 45-30 | |
| » W: Dave Schmidt (2-1) L: Don Aase (3-3) | First | -- |
| Thursday, July 1 |
| » Lost to Rangers (29-40), 7-2 | Arlington Stadium (1-2) | 45-31 | Lost 2 |
| » W: Frank Tanana (4-9) L: Mike Witt (4-2) | First | -- |
| Friday, July 2 |
| » Lost to Royals (42-32), 7-2 | Royals Stadium (0-1) | 45-32 | Lost 3 |
| » W: Vida Blue (5-5) L: Steve Renko (7-2) S: Mike Armstrong (2) | First | -- |
| Saturday, July 3 |
| » Lost to Royals (43-32), 6-2 | Royals Stadium (0-2) | 45-33 | Lost 4 |
| » W: Larry Gura (9-4) L: Dave Goltz (1-3) S: Dan Quisenberry (21) | First | -- |
| Sunday, July 4 |
| » Lost to Royals (44-32), 6-1 | Royals Stadium (0-3) | 45-34 | Lost 5 |
| » W: Bud Black (3-2) L: Geoff Zahn (9-4) | Second | 1½ out |
| Monday, July 5 |
| » Lost to Orioles (41-35), 8-5 | Anaheim Stadium (27-17) | 45-35 | Lost 6 |
| » W: Scott McGregor (9-6) L: Ken Forsch (7-7) S: Tippy Martinez (7) | Second | 1 out |
| Tuesday, July 6 |
| » Lost to Orioles (42-35), 3-2 | Anaheim Stadium (27-18) | 45-36 | Lost 7 |
| » W: Dennis Martinez (9-5) L: Doug Corbett (1-7) S: Tippy Martinez (8) | Second | 2 out |
| Wednesday, July 7 |
| » Lost to Indians (38-40), 8-6 | Anaheim Stadium (27-19) | 45-37 | Lost 8 |
| » W: Rick Waits (1-6) L: Mike Witt (4-3) S: Dan Spillner (10) | Second | 3 out |
| Thursday, July 8 |
| » Defeated Indians (38-41), 5-1 | Anaheim Stadium (28-19) | 46-37 | |
| » W: Dave Goltz (2-3) L: Lary Sorensen (7-7) S: Doug Corbett (10) | Second | 2 out |
| Friday, July 9 |
| » Defeated Yankees (39-40), 4-1 | Anaheim Stadium (29-19) | 47-37 | Won 2 |
| » W: Geoff Zahn (10-4) L: Tommy John (5-7) | Second | 1 out |
| Saturday, July 10 |
| » Defeated Yankees (39-41), 12-6 | Anaheim Stadium (30-19) | 48-37 | Won 3 |
| » W: Ken Forsch (8-7) L: Ron Guidry (8-4) S: Andy Hassler (1) | Second | 1 out |
| Sunday, July 11 |
| » Defeated Yankees (39-42), 2-1 | Anaheim Stadium (31-19) | 49-37 | Won 4 |
| » W: Andy Hassler (2-0) L: Rich Gossage (3-4) S: Don Aase (4) | First | -- |
| Thursday, July 15 |
| » Defeated Indians (41-42), 8-2 | Cleveland Stadium (2-1) | 50-37 | Won 5 |
| » W: Dave Goltz (3-3) L: Rick Waits (1-7) | First | -- |
| Friday, July 16 |
| » Defeated Indians (41-43), 15-0 | Cleveland Stadium (3-1) | 51-37 | Won 6 |
| » W: Ken Forsch (9-7) L: John Denny (6-10) | First | -- |
| Saturday, July 17 |
| » Lost to Indians (42-43), 10-4 | Cleveland Stadium (3-2) | 51-38 | |
| » W: Ed Glynn (3-0) L: Doug Corbett (1-8) | First | -- |
| » Major-league debuts: Carmen Castillo (Indians) |
| Sunday, July 18 |
| » Lost to Indians (43-43), 5-4 | Cleveland Stadium (3-3) | 51-39 | Lost 2 |
| » W: Ed Glynn (4-0) L: Doug Corbett (1-9) | First | -- |
| Monday, July 19 |
| » Defeated Orioles (47-40), 6-5 | Memorial Stadium (2-2) | 52-39 | |
| » W: Steve Renko (8-2) L: Scott McGregor (11-7) S: Bruce Kison (1) | First | -- |
| Tuesday, July 20 |
| » Defeated Orioles (47-41), 7-4 | Memorial Stadium (3-2) | 53-39 | Won 2 |
| » W: Dave Goltz (4-3) L: Dennis Martinez (9-8) S: Andy Hassler (2) | First | -- |
| Wednesday, July 21 |
| » Lost to Orioles (48-41), 8-7 | Memorial Stadium (3-3) | 53-40 | |
| » W: Sammy Stewart (7-5) L: Andy Hassler (2-1) S: Tippy Martinez (9) | First | -- |
| Friday, July 23 |
| » Lost to Yankees (46-44), 6-3 | Yankee Stadium (2-2) | 53-41 | Lost 2 |
| » W: Shane Rawley (6-5) L: Geoff Zahn (10-5) S: Dave Righetti (1) | First | -- |
| Saturday, July 24 |
| » Lost to Yankees (47-44), 6-5 | Yankee Stadium (2-3) | 53-42 | Lost 3 |
| » W: Rudy May (3-3) L: Bruce Kison (6-4) | First | -- |
| Sunday, July 25 |
| » Defeated Yankees (47-45), 6-4 | Yankee Stadium (3-3) | 54-42 | |
| » W: Mickey Mahler (1-0) L: Tommy John (6-8) | First | -- |
| Monday, July 26 |
| » Lost to Athletics (41-58), 11-8 | Anaheim Stadium (31-20) | 54-43 | |
| » W: Dave Beard (6-7) L: Luis Sanchez (3-1) | First | -- |
| Tuesday, July 27 |
| » Defeated Athletics (41-59), 8-7 | Anaheim Stadium (32-20) | 55-43 | |
| » W: Dave Goltz (5-3) L: Bob Owchinko (1-3) | First | -- |
| Wednesday, July 28 |
| » Defeated Athletics (41-60), 13-1 | Anaheim Stadium (33-20) | 56-43 | Won 2 |
| » W: Mike Witt (5-3) L: Matt Keough (7-15) | First | -- |
| Thursday, July 29 |
| » Defeated Mariners (51-49), 3-1 | Anaheim Stadium (34-20) | 57-43 | Won 3 |
| » W: Steve Renko (9-2) L: Mike Moore (5-8) S: Luis Sanchez (2) | First | -- |
| Friday, July 30 |
| » Defeated Mariners (51-50), 2-0 | Anaheim Stadium (35-20) | 58-43 | Won 4 |
| » W: Ken Forsch (10-7) L: Jim Beattie (6-8) | First | -- |
| Saturday, July 31 |
| » Lost to Mariners (52-50), 9-3 | Anaheim Stadium (35-21) | 58-44 | |
| » W: Floyd Bannister (10-6) L: Dave Goltz (5-4) | First | -- |
| Sunday, August 1 |
| » Defeated Mariners (52-51), 9-4 | Anaheim Stadium (36-21) | 59-44 | |
| » W: Geoff Zahn (11-5) L: Rich Bordi (0-1) | First | -- |
| Monday, August 2 |
| » Lost to Twins (36-69), 9-7 | Anaheim Stadium (36-22) | 59-45 | |
| » W: Jeff Little (2-0) L: Luis Sanchez (3-2) S: Ron Davis (13) | Second | 1 out |
| Tuesday, August 3 |
| » Lost to Twins (37-69), 5-4 | Anaheim Stadium (36-23) | 59-46 | Lost 2 |
| » W: Brad Havens (8-7) L: Steve Renko (9-3) S: Terry Felton (3) | Second | 1 out |
| Wednesday, August 4 |
| » Defeated Twins (37-70), 8-6 | Anaheim Stadium (37-23) | 60-46 | |
| » W: Dave Goltz (6-4) L: Terry Felton (0-10) | Second | 1 out |
| Thursday, August 5 |
| » Lost to Twins (38-70), 8-6 | Anaheim Stadium (37-24) | 60-47 | |
| » W: Jack O'Connor (5-3) L: Luis Tiant (0-1) S: Ron Davis (14) | Second | 1 out |
| Friday, August 6 |
| » Defeated Mariners (54-54), 11-9 | Kingdome (2-2) | 61-47 | |
| » W: Luis Sanchez (4-2) L: Floyd Bannister (10-7) S: Andy Hassler (3) | Second | ½ out |
| Saturday, August 7 |
| » Defeated Mariners (54-55), 3-1 | Kingdome (3-2) | 62-47 | Won 2 |
| » W: Mike Witt (6-3) L: Gaylord Perry (7-9) | First | -- |
| Sunday, August 8 |
| » Defeated Mariners (54-56), 9-5 | Kingdome (4-2) | 63-47 | Won 3 |
| » W: Steve Renko (10-3) L: Mike Moore (6-9) S: Andy Hassler (4) | First | -- |
| Tuesday, August 10 |
| » Lost to Twins (39-73), 5-2 | Hubert H. Humphrey Metrodome (1-3) | 63-48 | |
| » W: Pete Redfern (5-9) L: Ken Forsch (10-8) S: Ron Davis (15) | First | -- |
| Wednesday, August 11 |
| » Defeated Twins (39-74), 6-3 | Hubert H. Humphrey Metrodome (2-3) | 64-48 | |
| » W: Geoff Zahn (12-5) L: Terry Felton (0-11) S: Dave Goltz (1) | First | -- |
| Thursday, August 12 |
| » Defeated Twins (39-75), 3-1 | Hubert H. Humphrey Metrodome (3-3) | 65-48 | Won 2 |
| » W: Luis Tiant (1-1) L: Frank Viola (3-4) S: Luis Sanchez (3) | First | -- |
| Friday, August 13 |
| » Defeated Athletics (50-66), 9-0 | Oakland-Alameda County Stadium (3-1) | 66-48 | Won 3 |
| » W: Mike Witt (7-3) L: Mike Norris (6-7) | First | -- |
| Saturday, August 14 |
| » Lost to Athletics (51-66), 10-1 | Oakland-Alameda County Stadium (3-2) | 66-49 | |
| » W: Matt Keough (10-15) L: Steve Renko (10-4) S: Tom Underwood (5) | First | -- |
| Sunday, August 15 |
| » Lost to Athletics (52-66), 3-2 | Oakland-Alameda County Stadium (3-3) | 66-50 | Lost 2 |
| » W: Tom Underwood (9-4) L: Dave Goltz (6-5) | Second | ½ out |
| Monday, August 16 |
| » Defeated Athletics (52-67), 8-4 | Oakland-Alameda County Stadium (4-3) | 67-50 | |
| » W: Geoff Zahn (13-5) L: Steve McCatty (6-3) S: Dave Goltz (2) | First | -- |
| Tuesday, August 17 |
| » Defeated Red Sox (64-53), 10-2 | Anaheim Stadium (38-24) | 68-50 | Won 2 |
| » W: Luis Tiant (2-1) L: Bob Ojeda (4-6) | First | -- |
| Wednesday, August 18 |
| » Lost to Red Sox (65-53), 4-1 | Anaheim Stadium (38-25) | 68-51 | |
| » W: John Tudor (9-9) L: Mike Witt (7-4) S: Bob Stanley (10) | First | -- |
| Thursday, August 19 |
| » Defeated Red Sox (65-54), 8-5 | Anaheim Stadium (39-25) | 69-51 | |
| » W: Bruce Kison (7-4) L: Mark Clear (9-6) | First | -- |
| Friday, August 20 |
| » Lost to Tigers (62-58), 8-6 | Anaheim Stadium (39-26) | 69-52 | |
| » W: Jerry Ujdur (7-6) L: Ken Forsch (10-9) S: Dave Tobik (8) | First | -- |
| Saturday, August 21 |
| » Defeated Tigers (62-59), 13-1 | Anaheim Stadium (40-26) | 70-52 | |
| » W: Geoff Zahn (14-5) L: Jack Morris (14-12) | First | -- |
| Sunday, August 22 |
| » Defeated Tigers (62-60), 6-5 | Anaheim Stadium (41-26) | 71-52 | Won 2 |
| » W: Luis Sanchez (5-2) L: Dave Rucker (2-4) | First | -- |
| Monday, August 23 |
| » Defeated Brewers (72-51), 5-3 | Anaheim Stadium (42-26) | 72-52 | Won 3 |
| » W: Mike Witt (8-4) L: Bob McClure (9-6) | First | -- |
| Tuesday, August 24 |
| » Lost to Brewers (73-51), 7-3 | Anaheim Stadium (42-27) | 72-53 | |
| » W: Pete Vuckovich (15-4) L: Steve Renko (10-5) | First | -- |
| Thursday, August 26 |
| » Defeated Red Sox (68-57), 10-1 | Fenway Park (2-0) | 73-53 | |
| » W: Ken Forsch (11-9) L: Mike Torrez (7-8) | First | -- |
| » Lost to Red Sox (69-57), 4-3 | Fenway Park (2-1) | 73-54 | |
| » W: Bob Stanley (9-6) L: Geoff Zahn (14-6) | First | -- |
| Friday, August 27 |
| » Defeated Red Sox (69-58), 7-6 | Fenway Park (3-1) | 74-54 | |
| » W: Rick Steirer (1-0) L: Brian Denman (1-1) S: Doug Corbett (11) | First | -- |
| Saturday, August 28 |
| » Lost to Red Sox (70-58), 7-6 | Fenway Park (3-2) | 74-55 | |
| » W: Mark Clear (11-7) L: Bruce Kison (7-5) | Second | 1 out |
| Sunday, August 29 |
| » Lost to Red Sox (71-58), 9-3 | Fenway Park (3-3) | 74-56 | Lost 2 |
| » W: Dennis Eckersley (12-10) L: Steve Renko (10-6) S: Bob Stanley (11) | Second | 2 out |
| Tuesday, August 31 |
| » Defeated Tigers (65-64), 11-0 | Tiger Stadium (3-1) | 75-56 | |
| » W: Geoff Zahn (15-6) L: Jack Morris (14-14) | Second | 1½ out |
| Wednesday, September 1 |
| » Lost to Tigers (66-64), 5-3 | Tiger Stadium (3-2) | 75-57 | |
| » W: Milt Wilcox (9-7) L: Ken Forsch (11-10) S: Pat Underwood (3) | Second | 1½ out |
| » Major-league debuts: Mike Laga (Tigers) |
| Thursday, September 2 |
| » Lost to Tigers (67-64), 6-3 | Tiger Stadium (3-3) | 75-58 | Lost 2 |
| » W: Aurelio Lopez (2-1) L: Mike Witt (8-5) | Second | 2 out |
| Friday, September 3 |
| » Defeated Brewers (79-55), 5-2 | County Stadium (3-1) | 76-58 | |
| » W: Tommy John (11-10) L: Bob McClure (10-7) | Second | 2 out |
| Saturday, September 4 |
| » Lost to Brewers (80-55), 8-2 | County Stadium (3-2) | 76-59 | |
| » W: Pete Vuckovich (16-4) L: Luis Tiant (2-2) | Second | 2 out |
| Sunday, September 5 |
| » Lost to Brewers (81-55), 8-5 | County Stadium (3-3) | 76-60 | Lost 2 |
| » W: Mike Caldwell (14-11) L: Geoff Zahn (15-7) S: Pete Ladd (3) | Second | 2 out |
| Monday, September 6 |
| » Defeated White Sox (72-64), 8-6 | Anaheim Stadium (43-27) | 77-60 | |
| » W: Steve Renko (11-6) L: Jim Kern (4-6) | Second | 1 out |
| Tuesday, September 7 |
| » Lost to White Sox (73-64), 7-4 | Anaheim Stadium (43-28) | 77-61 | |
| » W: La Marr Hoyt (15-13) L: Tommy John (11-11) S: Salome Barojas (16) | Second | 1 out |
| Wednesday, September 8 |
| » Lost to White Sox (74-64), 5-3 | Anaheim Stadium (43-29) | 77-62 | Lost 2 |
| » W: Richard Dotson (11-11) L: John Curtis (8-7) S: Salome Barojas (17) | Second | 2 out |
| Friday, September 10 |
| » Defeated Blue Jays (65-76), 6-2 | Anaheim Stadium (44-29) | 78-62 | |
| » W: Geoff Zahn (16-7) L: Luis Leal (10-13) | Second | 1 out |
| Saturday, September 11 |
| » Defeated Blue Jays (65-77), 4-1 | Anaheim Stadium (45-29) | 79-62 | Won 2 |
| » W: Ken Forsch (12-10) L: Dave Stieb (14-14) | Second | 1 out |
| Sunday, September 12 |
| » Defeated Blue Jays (65-78), 3-2 | Anaheim Stadium (46-29) | 80-62 | Won 3 |
| » W: Tommy John (12-11) L: Jim Clancy (12-14) S: John Curtis (1) | Second | 1 out |
| » Major-league debuts: Dave Baker (Blue Jays) |
| Monday, September 13 |
| » Defeated White Sox (76-66), 6-4 | Comiskey Park I (4-1) | 81-62 | Won 4 |
| » W: Luis Sanchez (6-2) L: Kevin Hickey (4-3) | Second | 1 out |
| » Major-league debuts: Gary Pettis (Angels) |
| Tuesday, September 14 |
| » Defeated White Sox (76-67), 7-0 | Comiskey Park I (5-1) | 82-62 | Won 5 |
| » W: Bruce Kison (8-5) L: Dennis Lamp (9-8) | Second | 1 out |
| Wednesday, September 15 |
| » Lost to White Sox (77-67), 8-3 | Comiskey Park I (5-2) | 82-63 | |
| » W: Jerry Koosman (9-6) L: Geoff Zahn (16-8) | Second | 2 out |
| Thursday, September 16 |
| » Lost to Blue Jays (68-78), 2-1 | Exhibition Stadium (1-2) | 82-64 | Lost 2 |
| » W: Roy Lee Jackson (7-8) L: Luis Sanchez (6-3) | Second | 2 out |
| Friday, September 17 |
| » Lost to Blue Jays (69-78), 6-2 | Exhibition Stadium (1-3) | 82-65 | Lost 3 |
| » W: Jim Clancy (13-14) L: Tommy John (12-12) S: Dale Murray (10) | Second | 2 out |
| Saturday, September 18 |
| » Defeated Blue Jays (69-79), 8-6 | Exhibition Stadium (2-3) | 83-65 | |
| » W: Luis Sanchez (7-3) L: Dale Murray (8-6) | Second | 1 out |
| Sunday, September 19 |
| » Defeated Blue Jays (69-80), 5-1 | Exhibition Stadium (3-3) | 84-65 | Won 2 |
| » W: Bruce Kison (9-5) L: Mark Eichhorn (0-2) | First | -- |
| Monday, September 20 |
| » Defeated Royals (84-66), 3-2 | Anaheim Stadium (47-29) | 85-65 | Won 3 |
| » W: Geoff Zahn (17-8) L: Larry Gura (17-11) S: Luis Sanchez (4) | First | -- |
| Tuesday, September 21 |
| » Defeated Royals (84-67), 2-1 | Anaheim Stadium (48-29) | 86-65 | Won 4 |
| » W: Ken Forsch (13-10) L: Dan Quisenberry (8-6) | First | -- |
| Wednesday, September 22 |
| » Defeated Royals (84-68), 8-5 | Anaheim Stadium (49-29) | 87-65 | Won 5 |
| » W: Tommy John (13-12) L: Vida Blue (13-11) S: Dave Goltz (3) | First | -- |
| Thursday, September 23 |
| » Lost to Rangers (61-92), 5-4 | Arlington Stadium (1-3) | 87-66 | |
| » W: Danny Darwin (10-6) L: Mike Witt (8-6) | First | -- |
| Friday, September 24 |
| » Defeated Rangers (61-93), 10-1 | Arlington Stadium (2-3) | 88-66 | |
| » W: Bruce Kison (10-5) L: Rick Honeycutt (5-17) | First | -- |
| Saturday, September 25 |
| » Defeated Rangers (61-94), 6-5 | Arlington Stadium (3-3) | 89-66 | Won 2 |
| » W: Dave Goltz (7-5) L: Danny Darwin (10-7) | First | -- |
| Sunday, September 26 |
| » Lost to Rangers (62-94), 7-5 | Arlington Stadium (3-4) | 89-67 | |
| » W: Charlie Hough (16-12) L: Ken Forsch (13-11) | First | -- | <