| Wednesday, January 21 |
| Future Tiger Wilfredo Ledezma is born in Guarico, Venezuela. |
| Monday, January 26 |
| Former Tiger Ray Oyler dies in Seattle, WA at the age of 43. |
| Monday, March 16 |
| Future Tiger Curtis Granderson is born in Blue Island, IL. |
| Friday, March 20 |
| Former Tiger Gee Walker dies in Whitfield, MS at the age of 74. |
| Thursday, April 9 |
| » Defeated Blue Jays (0-1), 6-2 | Tiger Stadium (1-0) | 1-0 | |
| » W: Jack Morris (1-0) L: Joey McLaughlin (0-1) | First | -- |
| » Major-league debuts: George Bell (Blue Jays) |
| Friday, April 10 |
| » Major-league debuts: Chili Davis (Giants) |
| Saturday, April 11 |
| » Defeated Blue Jays (0-2), 6-2 | Tiger Stadium (2-0) | 2-0 | Won 2 |
| » W: Milt Wilcox (1-0) L: Dave Stieb (0-1) | First | -- |
| » Major-league debuts: Darrell Brown (Tigers) |
| Sunday, April 12 |
| » Lost to Blue Jays (1-2), 6-2 | Tiger Stadium (2-1) | 2-1 | |
| » W: Luis Leal (1-0) L: Howard Bailey (0-1) | Second | ½ out |
| » Major-league debuts: Howard Bailey and Dave Rucker (Tigers) |
| Tuesday, April 14 |
| » Defeated Royals (1-2), 6-5 | Royals Stadium (1-0) | 3-1 | |
| » W: Aurelio Lopez (1-0) L: Dan Quisenberry (0-1) | First | -- |
| Wednesday, April 15 |
| » Defeated Royals (1-3), 4-0 | Royals Stadium (2-0) | 4-1 | Won 2 |
| » W: Dave Rozema (1-0) L: Larry Gura (0-2) | First | -- |
| Thursday, April 16 |
| » Defeated Blue Jays (2-4), 2-0 | Exhibition Stadium (1-0) | 5-1 | Won 3 |
| » W: Milt Wilcox (2-0) L: Dave Stieb (0-2) S: Aurelio Lopez (1) | First | -- |
| Friday, April 17 |
| » Defeated Blue Jays (2-5), 8-5 | Exhibition Stadium (2-0) | 6-1 | Won 4 |
| » W: Howard Bailey (1-1) L: Luis Leal (1-1) S: Kevin Saucier (1) | First | -- |
| Future Tiger Ryan Raburn is born in Tampa, FL. |
| Saturday, April 18 |
| » Defeated Blue Jays (2-6), 4-3 | Exhibition Stadium (3-0) | 7-1 | Won 5 |
| » W: Dan Schatzeder (1-0) L: Jim Clancy (1-1) S: Aurelio Lopez (2) | First | -- |
| Sunday, April 19 |
| » Lost to Blue Jays (3-6), 9-1 | Exhibition Stadium (3-1) | 7-2 | |
| » W: Mark Bomback (1-0) L: Jack Morris (1-1) | First | -- |
| Monday, April 20 |
| » Lost to Yankees (5-4), 6-2 | Yankee Stadium (0-1) | 7-3 | Lost 2 |
| » W: Rudy May (3-0) L: Dave Rozema (1-1) | First | -- |
| Tuesday, April 21 |
| » Lost to Yankees (6-4), 2-0 | Yankee Stadium (0-2) | 7-4 | Lost 3 |
| » W: Doug Bird (1-0) L: Milt Wilcox (2-1) S: Rich Gossage (3) | Second | 1 out |
| Wednesday, April 22 |
| » Lost to Yankees (7-4), 7-2 | Yankee Stadium (0-3) | 7-5 | Lost 4 |
| » W: Dave LaRoche (1-0) L: Howard Bailey (1-2) | Fourth | 1½ out |
| » Major-league debuts: Steve Balboni (Yankees) |
| Friday, April 24 |
| » Lost to White Sox (8-3), 3-2 | Tiger Stadium (2-2) | 7-6 | Lost 5 |
| » W: La Marr Hoyt (3-0) L: Jack Morris (1-2) | Fourth | 1½ out |
| Saturday, April 25 |
| » Lost to White Sox (9-3), 4-0 | Tiger Stadium (2-3) | 7-7 | Lost 6 |
| » W: Ross Baumgarten (2-1) L: Dave Rozema (1-2) S: La Marr Hoyt (2) | Fourth | 1½ out |
| Sunday, April 26 |
| » Lost to White Sox (10-3), 5-4 | Tiger Stadium (2-4) | 7-8 | Lost 7 |
| » W: Britt Burns (2-0) L: Milt Wilcox (2-2) S: Ed Farmer (3) | Fourth | 2 out |
| Monday, April 27 |
| » Lost to Yankees (9-6), 3-1 | Tiger Stadium (2-5) | 7-9 | Lost 8 |
| » W: Ron Guidry (2-1) L: Howard Bailey (1-3) S: Rich Gossage (5) | Fifth | 2½ out |
| Tuesday, April 28 |
| » Lost to Yankees (10-6), 4-1 | Tiger Stadium (2-6) | 7-10 | Lost 9 |
| » W: Tommy John (3-1) L: Dan Schatzeder (1-1) | Fifth | 3 out |
| Wednesday, April 29 |
| » Lost to Yankees (11-6), 3-2 | Tiger Stadium (2-7) | 7-11 | Lost 10 |
| » W: Rudy May (4-1) L: Jack Morris (1-3) S: Ron Davis (1) | Sixth | 4½ out |
| Thursday, April 30 |
| » Defeated Mariners (5-14), 2-0 | Kingdome (1-0) | 8-11 | |
| » W: Dave Rozema (2-2) L: Jerry Don Gleaton (2-3) | Sixth | 3½ out |
| » Major-league debuts: Rick Leach (Tigers) |
| Friday, May 1 |
| » Defeated Mariners (5-15), 7-3 | Kingdome (2-0) | 9-11 | Won 2 |
| » W: Milt Wilcox (3-2) L: Mike Parrott (0-2) S: Kevin Saucier (2) | Fifth | 3½ out |
| Saturday, May 2 |
| » Lost to Mariners (6-15), 3-1 | Kingdome (2-1) | 9-12 | |
| » W: Floyd Bannister (2-2) L: Dan Petry (0-1) S: Dick Drago (2) | Fifth | 4½ out |
| Sunday, May 3 |
| » Defeated Mariners (6-16), 8-5 | Kingdome (3-1) | 10-12 | |
| » W: Jack Morris (2-3) L: Larry Andersen (1-2) | Fifth | 3½ out |
| Tuesday, May 5 |
| » Lost to Athletics (21-5), 6-2 | Oakland-Alameda County Stadium (0-1) | 10-13 | |
| » W: Mike Norris (6-0) L: Dave Rozema (2-3) | Fifth | 4 out |
| Wednesday, May 6 |
| » Defeated Athletics (21-6), 3-2 | Oakland-Alameda County Stadium (1-1) | 11-13 | |
| » W: Milt Wilcox (4-2) L: Rick Langford (4-2) | Fifth | 4 out |
| Thursday, May 7 |
| » Lost to Athletics (22-6), 5-3 | Oakland-Alameda County Stadium (1-2) | 11-14 | |
| » W: Jeff Jones (2-0) L: Dan Petry (0-2) S: Bo McLaughlin (1) | Fifth | 4 out |
| Friday, May 8 |
| » Defeated Angels (13-16), 6-1 | Anaheim Stadium (1-0) | 12-14 | |
| » W: Jack Morris (3-3) L: Steve Renko (1-2) | Fifth | 4 out |
| Former Tiger Eddie Onslow dies in Dennison, OH at the age of 89. |
| Saturday, May 9 |
| » Lost to Angels (14-16), 15-1 | Anaheim Stadium (1-1) | 12-15 | |
| » W: Geoff Zahn (4-3) L: Dan Schatzeder (1-2) | Sixth | 4 out |
| Sunday, May 10 |
| » Lost to Angels (15-16), 4-3 | Anaheim Stadium (1-2) | 12-16 | Lost 2 |
| » W: Andy Hassler (2-1) L: Aurelio Lopez (1-1) S: Don Aase (3) | Sixth | 5 out |
| Tuesday, May 12 |
| » Defeated Mariners (10-20), 6-2 | Tiger Stadium (3-7) | 13-16 | |
| » W: Milt Wilcox (5-2) L: Floyd Bannister (3-3) | Sixth | 4½ out |
| Wednesday, May 13 |
| » Defeated Mariners (10-21), 1-0 | Tiger Stadium (4-7) | 14-16 | Won 2 |
| » W: Dan Petry (1-2) L: Dick Drago (1-1) | Fifth | 4½ out |
| Friday, May 15 |
| » Defeated Angels (18-17), 5-1 | Tiger Stadium (5-7) | 15-16 | Won 3 |
| » W: Jack Morris (4-3) L: Mike Witt (2-3) | Sixth | 4½ out |
| Saturday, May 16 |
| » Defeated Angels (18-18), 7-5 | Tiger Stadium (6-7) | 16-16 | Won 4 |
| » W: Dave Tobik (1-0) L: Doug Rau (0-1) S: Kevin Saucier (3) | Fifth | 3½ out |
| Former Tiger Jim Finigan dies in Quincy, IL at the age of 53. |
| Sunday, May 17 |
| » Lost to Angels (19-18), 7-1 | Tiger Stadium (6-8) | 16-17 | |
| » W: Ken Forsch (6-1) L: Milt Wilcox (5-3) | Sixth | 5 out |
| Monday, May 18 |
| » Lost to Rangers (19-14), 13-5 | Tiger Stadium (6-9) | 16-18 | Lost 2 |
| » W: Jon Matlack (2-3) L: Dan Petry (1-3) | Sixth | 5½ out |
| Tuesday, May 19 |
| » Defeated Rangers (19-15), 14-1 | Tiger Stadium (7-9) | 17-18 | |
| » W: Dan Schatzeder (2-2) L: Doc Medich (3-3) | Sixth | 5½ out |
| Wednesday, May 20 |
| » Defeated Rangers (19-16), 8-4 | Tiger Stadium (8-9) | 18-18 | Won 2 |
| » W: Jack Morris (5-3) L: Fergie Jenkins (2-3) | Sixth | 5½ out |
| Friday, May 22 |
| » Lost to Orioles (23-12), 4-2 | Tiger Stadium (8-10) | 18-19 | |
| » W: Scott McGregor (5-1) L: Milt Wilcox (5-4) S: Tippy Martinez (7) | Sixth | 6 out |
| Saturday, May 23 |
| » Lost to Orioles (24-12), 9-2 | Tiger Stadium (8-11) | 18-20 | Lost 2 |
| » W: Mike Flanagan (6-3) L: Dave Rozema (2-4) S: Sammy Stewart (3) | Sixth | 7 out |
| Sunday, May 24 |
| » Defeated Orioles (24-13), 8-2 | Tiger Stadium (9-11) | 19-20 | |
| » W: Dan Petry (2-3) L: Dennis Martinez (5-2) S: Kevin Saucier (4) | Sixth | 5 out |
| » Defeated Orioles (24-14), 5-3 | Tiger Stadium (10-11) | 20-20 | Won 2 |
| » W: Dave Tobik (2-0) L: Tippy Martinez (1-1) | Sixth | 5 out |
| Monday, May 25 |
| » Defeated Brewers (22-18), 12-3 | County Stadium (1-0) | 21-20 | Won 3 |
| » W: Jack Morris (6-3) L: Jerry Augustine (1-1) | Sixth | 5 out |
| Tuesday, May 26 |
| » Lost to Brewers (23-18), 7-3 | County Stadium (1-1) | 21-21 | |
| » W: Pete Vuckovich (5-2) L: Milt Wilcox (5-5) | Fifth | 6 out |
| Former Tiger George Smith dies in Richmond, VA at the age of 80. |
| Wednesday, May 27 |
| » Lost to Brewers (24-18), 5-1 | County Stadium (1-2) | 21-22 | Lost 2 |
| » W: Randy Lerch (3-4) L: Howard Bailey (1-4) | Sixth | 7 out |
| Thursday, May 28 |
| » Lost to Brewers (25-18), 7-1 | County Stadium (1-3) | 21-23 | Lost 3 |
| » W: Mike Caldwell (5-4) L: Dan Petry (2-4) S: Rollie Fingers (9) | Sixth | 7½ out |
| Friday, May 29 |
| » Lost to Orioles (28-14), 6-5 | Memorial Stadium (0-1) | 21-24 | Lost 4 |
| » W: Dennis Martinez (6-2) L: Dan Schatzeder (2-3) S: Tippy Martinez (8) | Sixth | 8½ out |
| Saturday, May 30 |
| » Defeated Orioles (28-15), 4-1 | Memorial Stadium (1-1) | 22-24 | |
| » W: Jack Morris (7-3) L: Jim Palmer (3-3) | Sixth | 7½ out |
| Sunday, May 31 |
| » Defeated Orioles (28-16), 5-4 | Memorial Stadium (2-1) | 23-24 | Won 2 |
| » W: Aurelio Lopez (2-1) L: Scott McGregor (5-2) S: Kevin Saucier (5) | Sixth | 6½ out |
| Monday, June 1 |
| » Defeated Brewers (27-20), 4-3 | Tiger Stadium (11-11) | 24-24 | Won 3 |
| » W: Dave Rozema (3-4) L: Reggie Cleveland (2-1) | Sixth | 6 out |
| Tuesday, June 2 |
| » Lost to Brewers (28-20), 5-2 | Tiger Stadium (11-12) | 24-25 | |
| » W: Mike Caldwell (6-4) L: Dan Petry (2-5) S: Rollie Fingers (10) | Sixth | 6 out |
| Wednesday, June 3 |
| » Defeated Brewers (28-21), 4-1 | Tiger Stadium (12-12) | 25-25 | |
| » W: Dan Schatzeder (3-3) L: Jim Slaton (3-3) S: Kevin Saucier (6) | Sixth | 5 out |
| Friday, June 5 |
| » Defeated Twins (15-35), 2-0 | Tiger Stadium (13-12) | 26-25 | Won 2 |
| » W: Jack Morris (8-3) L: Brad Havens (0-1) | Sixth | 4½ out |
| » Major-league debuts: Brad Havens (Twins) |
| Saturday, June 6 |
| » Defeated Twins (15-36), 5-1 | Tiger Stadium (14-12) | 27-25 | Won 3 |
| » W: Dan Petry (3-5) L: Pete Redfern (3-6) | Sixth | 4½ out |
| Sunday, June 7 |
| » Defeated Twins (15-37), 3-0 | Tiger Stadium (15-12) | 28-25 | Won 4 |
| » W: Milt Wilcox (6-5) L: Jerry Koosman (3-8) | Sixth | 4½ out |
| Monday, June 8 |
| » Lost to Rangers (32-20), 8-1 | Arlington Stadium (0-1) | 28-26 | |
| » W: Rick Honeycutt (6-1) L: Dan Schatzeder (3-4) | Sixth | 5½ out |
| Tuesday, June 9 |
| » Defeated Rangers (32-21), 5-0 | Arlington Stadium (1-1) | 29-26 | |
| » W: Aurelio Lopez (3-1) L: Jon Matlack (3-5) S: Kevin Saucier (7) | Sixth | 5½ out |
| Wednesday, June 10 |
| » Defeated Twins (17-38), 4-2 | Metropolitan Stadium (1-0) | 30-26 | Won 2 |
| » W: Jack Morris (9-3) L: Brad Havens (0-2) | Fourth | 4½ out |
| Thursday, June 11 |
| » Defeated Twins (17-39), 7-2 | Metropolitan Stadium (2-0) | 31-26 | Won 3 |
| » W: Dan Petry (4-5) L: Pete Redfern (3-7) | Fourth | 3½ out |
| Tuesday, July 21 |
| Former Tiger Jim McGarr dies in Miami, FL at the age of 93. |
| Monday, August 10 |
| » Defeated Blue Jays (16-43), 4-3 | Tiger Stadium (16-12) | 32-26 | Won 4 |
| » W: Kevin Saucier (1-0) L: Joey McLaughlin (0-5) | Fourth | 3½ out |
| Tuesday, August 11 |
| » Lost to Blue Jays (17-43), 6-4 | Tiger Stadium (16-13) | 32-27 | |
| » W: Juan Berenguer (1-4) L: Dan Schatzeder (3-5) S: Roy Lee Jackson (3) | Fourth | 3½ out |
| Wednesday, August 12 |
| » Lost to Blue Jays (18-43), 4-3 | Tiger Stadium (16-14) | 32-28 | Lost 2 |
| » W: Dave Stieb (5-7) L: Jack Morris (9-4) S: Roy Lee Jackson (4) | Fourth | 4½ out |
| Thursday, August 13 |
| » Lost to Yankees (37-23), 3-0 | Tiger Stadium (16-15) | 32-29 | Lost 3 |
| » W: Ron Guidry (6-3) L: Dan Petry (4-6) S: Ron Davis (5) | Fifth | 5½ out |
| Friday, August 14 |
| » Defeated Yankees (37-24), 1-0 | Tiger Stadium (17-15) | 33-29 | |
| » W: Milt Wilcox (7-5) L: Rudy May (4-6) S: Kevin Saucier (8) | Fourth | 4½ out |
| Saturday, August 15 |
| » Defeated Yankees (37-25), 8-5 | Tiger Stadium (18-15) | 34-29 | Won 2 |
| » W: Dan Schatzeder (4-5) L: Dave LaRoche (4-1) S: Kevin Saucier (9) | Fourth | 3½ out |
| Sunday, August 16 |
| » Defeated Yankees (37-26), 5-4 | Tiger Stadium (19-15) | 35-29 | Won 3 |
| » W: Aurelio Lopez (4-1) L: Ron Davis (2-3) | Fourth | 2½ out |
| Monday, August 17 |
| » Defeated Twins (20-45), 12-2 | Tiger Stadium (20-15) | 36-29 | Won 4 |
| » W: Dan Petry (5-6) L: Jerry Koosman (3-9) S: Dave Rozema (1) | Fourth | 1½ out |
| Tuesday, August 18 |
| » Defeated Twins (20-46), 3-0 | Tiger Stadium (21-15) | 37-29 | Won 5 |
| » W: Milt Wilcox (8-5) L: Roger Erickson (3-8) S: Kevin Saucier (10) | Fourth | 1½ out |
| Wednesday, August 19 |
| » Defeated Twins (20-47), 4-0 | Tiger Stadium (22-15) | 38-29 | Won 6 |
| » W: Dan Schatzeder (5-5) L: Darrell Jackson (1-2) S: Dave Tobik (1) | Third | ½ out |
| » Major-league debuts: Marty Castillo (Tigers) |
| Thursday, August 20 |
| » Major-league debuts: Brett Butler (Braves) |
| Friday, August 21 |
| » Defeated Rangers (38-27), 7-4 | Tiger Stadium (23-15) | 39-29 | Won 7 |
| » W: Aurelio Lopez (5-1) L: Danny Darwin (7-6) S: Kevin Saucier (11) | First | -- |
| Saturday, August 22 |
| » Defeated Rangers (38-28), 2-0 | Tiger Stadium (24-15) | 40-29 | Won 8 |
| » W: Dan Petry (6-6) L: Rick Honeycutt (8-2) S: Kevin Saucier (12) | First | -- |
| Sunday, August 23 |
| » Defeated Rangers (38-29), 5-4 | Tiger Stadium (25-15) | 41-29 | Won 9 |
| » W: Dave Rozema (4-4) L: Jim Kern (1-2) | First | -- |
| Monday, August 24 |
| » Lost to Royals (27-38), 4-2 | Tiger Stadium (25-16) | 41-30 | |
| » W: Ken Brett (1-0) L: Dan Schatzeder (5-6) S: Dan Quisenberry (12) | First | -- |
| Tuesday, August 25 |
| » Defeated Royals (27-39), 4-3 | Tiger Stadium (26-16) | 42-30 | |
| » W: Kevin Saucier (2-0) L: Dan Quisenberry (0-4) | First | -- |
| Wednesday, August 26 |
| » Lost to Royals (28-39), 6-1 | Tiger Stadium (26-17) | 42-31 | |
| » W: Larry Gura (8-5) L: Aurelio Lopez (5-2) | Second | 2 out |
| Thursday, August 27 |
| » Lost to Twins (24-50), 4-3 | Metropolitan Stadium (2-1) | 42-32 | Lost 2 |
| » W: Pete Redfern (4-7) L: Kevin Saucier (2-1) | Second | 2 out |
| Friday, August 28 |
| » Lost to Twins (25-50), 6-0 | Metropolitan Stadium (2-2) | 42-33 | Lost 3 |
| » W: Fernando Arroyo (5-6) L: Dave Rozema (4-5) S: Jerry Koosman (5) | Third | 2 out |
| » Major-league debuts: Tim Laudner (Twins) |
| Saturday, August 29 |
| » Lost to Twins (26-50), 7-1 | Metropolitan Stadium (2-3) | 42-34 | Lost 4 |
| » W: Brad Havens (1-3) L: Dan Schatzeder (5-7) | Third | 2 out |
| Sunday, August 30 |
| » Defeated Twins (26-51), 6-1 | Metropolitan Stadium (3-3) | 43-34 | |
| » W: Jack Morris (10-4) L: Don Cooper (0-5) | Third | 1½ out |
| Monday, August 31 |
| » Defeated White Sox (41-32), 3-1 | Comiskey Park I (1-0) | 44-34 | Won 2 |
| » W: Milt Wilcox (9-5) L: Ross Baumgarten (5-7) | Third | 1½ out |
| Tuesday, September 1 |
| » Defeated White Sox (41-33), 2-1 | Comiskey Park I (2-0) | 45-34 | Won 3 |
| » W: Dan Petry (7-6) L: Jerry Koosman (3-10) | Third | 1½ out |
| Wednesday, September 2 |
| » Defeated White Sox (41-34), 5-4 | Comiskey Park I (3-0) | 46-34 | Won 4 |
| » W: Kevin Saucier (3-1) L: Jerry Koosman (3-11) S: Dave Rozema (2) | Third | ½ out |
| Thursday, September 3 |
| » Defeated Rangers (43-34), 8-5 | Arlington Stadium (2-1) | 47-34 | Won 5 |
| » W: Jack Morris (11-4) L: Jon Matlack (4-7) S: Kevin Saucier (13) | First | -- |
| Friday, September 4 |
| » Lost to Rangers (44-34), 3-2 | Arlington Stadium (2-2) | 47-35 | |
| » W: Doc Medich (8-4) L: Milt Wilcox (9-6) S: Mark Mercer (1) | Second | ½ out |
| Saturday, September 5 |
| » Defeated Rangers (44-35), 1-0 | Arlington Stadium (3-2) | 48-35 | |
| » W: Dan Petry (8-6) L: Fergie Jenkins (5-8) | Second | ½ out |
| Sunday, September 6 |
| » Defeated Rangers (44-36), 4-3 | Arlington Stadium (4-2) | 49-35 | Won 2 |
| » W: Kevin Saucier (4-1) L: Mark Mercer (0-1) S: Aurelio Lopez (3) | Second | ½ out |
| Former Tiger Eddie Ainsmith dies in Ft.Lauderdale, FL at the age of 90. |
| Monday, September 7 |
| » Defeated Red Sox (44-39), 3-1 | Tiger Stadium (27-17) | 50-35 | Won 3 |
| » W: Jack Morris (12-4) L: Bob Ojeda (4-2) | Second | ½ out |
| Tuesday, September 8 |
| » Lost to Red Sox (45-39), 5-3 | Tiger Stadium (27-18) | 50-36 | |
| » W: Mike Torrez (8-2) L: Milt Wilcox (9-7) S: Tom Burgmeier (7) | Third | 1 out |
| Wednesday, September 9 |
| » Lost to Red Sox (46-39), 6-5 | Tiger Stadium (27-19) | 50-37 | Lost 2 |
| » W: Bob Stanley (8-6) L: Dave Tobik (2-1) S: John Tudor (1) | Third | 1½ out |
| Friday, September 11 |
| » Defeated Indians (43-40), 6-3 | Tiger Stadium (28-19) | 51-37 | |
| » W: Dan Schatzeder (6-7) L: Rick Waits (6-9) | Second | 1½ out |
| » Major-league debuts: Larry Rothschild (Tigers) |
| Saturday, September 12 |
| » Defeated Indians (43-41), 11-9 | Tiger Stadium (29-19) | 52-37 | Won 2 |
| » W: Dave Rozema (5-5) L: Sid Monge (2-5) | Second | ½ out |
| Sunday, September 13 |
| » Defeated Indians (43-42), 8-6 | Tiger Stadium (30-19) | 53-37 | Won 3 |
| » W: Milt Wilcox (10-7) L: Dan Spillner (2-4) S: Larry Rothschild (1) | Second | ½ out |
| Monday, September 14 |
| » Lost to Red Sox (48-41), 5-2 | Fenway Park (0-1) | 53-38 | |
| » W: Bob Stanley (9-6) L: Dan Petry (8-7) | Second | 1½ out |
| Wednesday, September 16 |
| » Lost to Red Sox (49-41), 2-1 | Fenway Park (0-2) | 53-39 | Lost 2 |
| » W: Dennis Eckersley (8-6) L: Jack Morris (12-5) | Second | 1½ out |
| » Lost to Red Sox (50-41), 5-4 | Fenway Park (0-3) | 53-40 | Lost 3 |
| » W: Tom Burgmeier (4-5) L: Dave Tobik (2-2) | Second | 1½ out |
| Thursday, September 17 |
| » Lost to Red Sox (51-41), 6-1 | Fenway Park (0-4) | 53-41 | Lost 4 |
| » W: Bob Ojeda (6-2) L: Milt Wilcox (10-8) S: Bill Campbell (6) | Third | 2 out |
| Friday, September 18 |
| » Lost to Indians (44-44), 8-4 | Cleveland Stadium (0-1) | 53-42 | Lost 5 |
| » W: John Denny (9-4) L: Dan Schatzeder (6-8) S: Dan Spillner (6) | Fourth | 3 out |
| Saturday, September 19 |
| » Defeated Indians (44-45), 4-3 | Cleveland Stadium (1-1) | 54-42 | |
| » W: Dan Petry (9-7) L: Bert Blyleven (11-7) S: George Cappuzzello (1) | Third | 2 out |
| Sunday, September 20 |
| » Defeated Indians (44-46), 5-1 | Cleveland Stadium (2-1) | 55-42 | Won 2 |
| » W: Jack Morris (13-5) L: Tom Brennan (1-1) | Second | 1 out |
| Monday, September 21 |
| » Defeated Orioles (52-41), 5-1 | Memorial Stadium (3-1) | 56-42 | Won 3 |
| » W: Milt Wilcox (11-8) L: Scott McGregor (11-4) | Second | 1 out |
| Tuesday, September 22 |
| » Defeated Orioles (52-42), 6-3 | Memorial Stadium (4-1) | 57-42 | Won 4 |
| » W: George Cappuzzello (1-0) L: Sammy Stewart (3-7) | First | -- |
| Wednesday, September 23 |
| » Lost to Orioles (53-42), 1-0 | Memorial Stadium (4-2) | 57-43 | |
| » W: Dennis Martinez (14-4) L: Dan Petry (9-8) | Second | 1 out |
| Friday, September 25 |
| » Lost to Brewers (57-44), 8-6 | Tiger Stadium (30-20) | 57-44 | Lost 2 |
| » W: Jamie Easterly (3-3) L: Jack Morris (13-6) S: Rollie Fingers (27) | Second | 2 out |
| Saturday, September 26 |
| » Lost to Brewers (58-44), 4-3 | Tiger Stadium (30-21) | 57-45 | Lost 3 |
| » W: Moose Haas (10-7) L: Milt Wilcox (11-9) S: Rollie Fingers (28) | Fourth | 1 out |
| Sunday, September 27 |
| » Defeated Brewers (58-45), 2-1 | Tiger Stadium (31-21) | 58-45 | |
| » W: Dan Petry (10-8) L: Randy Lerch (6-9) | Second | ½ out |
| Monday, September 28 |
| » Lost to Orioles (56-44), 7-3 | Tiger Stadium (31-22) | 58-46 | |
| » W: Sammy Stewart (4-7) L: George Cappuzzello (1-1) | Fourth | 1 out |
| Tuesday, September 29 |
| » Defeated Orioles (56-45), 14-0 | Tiger Stadium (32-22) | 59-46 | |
| » W: Jack Morris (14-6) L: Scott McGregor (12-5) S: Dave Rozema (3) | First | -- |
| Thursday, October 1 |
| » Lost to Orioles (57-45), 5-4 | Tiger Stadium (32-23) | 59-47 | |
| » W: Tim Stoddard (4-2) L: Kevin Saucier (4-2) | Fourth | 1 out |
| Friday, October 2 |
| » Lost to Brewers (61-46), 8-2 | County Stadium (1-4) | 59-48 | Lost 2 |
| » W: Moose Haas (11-7) L: Dan Petry (10-9) | Fourth | 2 out |
| Saturday, October 3 |
| » Lost to Brewers (62-46), 2-1 | County Stadium (1-5) | 59-49 | Lost 3 |
| » W: Rollie Fingers (6-3) L: Jack Morris (14-7) | Fourth | 3 out |
| Sunday, October 4 |
| » Defeated Brewers (62-47), 3-2 | County Stadium (2-5) | 60-49 | |
| » W: Milt Wilcox (12-9) L: Jerry Augustine (2-2) | Fourth | 2 out |
| Tuesday, December 1 |
| Former Tiger Tony Piet dies in Hinsdale, IL at the age of 75. |
| Saturday, December 26 |
| Future Tiger Omar Infante is born in Puerto la Cruz, Venezuela. |
Game information provided by Retrosheet (www.retrosheet.org) |