| Friday, February 6 |
| Former Red Cactus Keck dies in Kirkwood, MO at the age of 83. |
| Sunday, February 22 |
| Former Red Andy High dies in Toledo, OH at the age of 84. |
| Saturday, March 7 |
| Former Red Paul Wanninger dies in N.Augusta, SC at the age of 79. |
| Friday, March 20 |
| Former Red Gee Walker dies in Whitfield, MS at the age of 74. |
| Monday, April 6 |
| Former Red Steve Mesner dies in San Diego, CA at the age of 64. |
| Wednesday, April 8 |
| » Defeated Phillies (0-1), 3-2 | Riverfront Stadium (1-0) | 1-0 | |
| » W: Tom Hume (1-0) L: Sparky Lyle (0-1) | First | -- |
| Friday, April 10 |
| » Lost to Braves (1-0), 5-3 | Atlanta-Fulton County Stadium (0-1) | 1-1 | |
| » W: Gene Garber (1-0) L: Mario Soto (0-1) S: Rick Camp (1) | Third | 1 out |
| » Major-league debuts: Rufino Linares (Braves) |
| Saturday, April 11 |
| » Defeated Braves (1-1), 3-2 | Atlanta-Fulton County Stadium (1-1) | 2-1 | |
| » W: Doug Bair (1-0) L: Gene Garber (1-1) | Second | ½ out |
| Sunday, April 12 |
| » Lost to Braves (2-1), 3-2 | Atlanta-Fulton County Stadium (1-2) | 2-2 | |
| » W: Larry Bradford (1-0) L: Tom Hume (1-1) S: Rick Mahler (1) | Third | 1½ out |
| Monday, April 13 |
| » Defeated Padres (2-3), 7-1 | San Diego/Jack Murphy Stadium (1-0) | 3-2 | |
| » W: Tom Seaver (1-0) L: Rick Wise (0-1) | Third | 1½ out |
| Tuesday, April 14 |
| » Defeated Padres (2-4), 4-0 | San Diego/Jack Murphy Stadium (2-0) | 4-2 | Won 2 |
| » W: Bruce Berenyi (1-0) L: John Curtis (0-1) | Second | 1½ out |
| Wednesday, April 15 |
| » Defeated Padres (2-5), 10-1 | San Diego/Jack Murphy Stadium (3-0) | 5-2 | Won 3 |
| » W: Mario Soto (1-1) L: Steve Mura (0-1) | Second | 1½ out |
| Friday, April 17 |
| » Lost to Cardinals (3-2), 9-5 | Riverfront Stadium (1-1) | 5-3 | |
| » W: Lary Sorensen (2-0) L: Mike LaCoss (0-1) | Second | 1½ out |
| Saturday, April 18 |
| » Lost to Cardinals (4-2), 10-4 | Riverfront Stadium (1-2) | 5-4 | Lost 2 |
| » W: Bob Shirley (1-0) L: Tom Seaver (1-1) | Second | 2½ out |
| » Major-league debuts: Joe Edelen (Cardinals) |
| Tuesday, April 21 |
| » Lost to Braves (5-5), 10-1 | Riverfront Stadium (1-3) | 5-5 | Lost 3 |
| » W: Tommy Boggs (1-1) L: Mario Soto (1-2) | Second | 3½ out |
| Wednesday, April 22 |
| » Lost to Braves (6-5), 7-3 | Riverfront Stadium (1-4) | 5-6 | Lost 4 |
| » W: Gaylord Perry (1-1) L: Mike LaCoss (0-2) | Third | 4½ out |
| Thursday, April 23 |
| » Defeated Astros (3-10), 5-4 | Astrodome (1-0) | 6-6 | |
| » W: Joe Price (1-0) L: Dave Smith (0-2) S: Paul Moskau (1) | Third | 4½ out |
| Friday, April 24 |
| » Defeated Astros (3-11), 3-0 | Astrodome (2-0) | 7-6 | Won 2 |
| » W: Frank Pastore (1-0) L: Joe Niekro (1-3) | Third | 3½ out |
| Saturday, April 25 |
| » Defeated Astros (3-12), 2-1 | Astrodome (3-0) | 8-6 | Won 3 |
| » W: Bruce Berenyi (2-0) L: Nolan Ryan (1-1) S: Tom Hume (1) | Third | 3½ out |
| Sunday, April 26 |
| » Lost to Astros (4-12), 1-0 | Astrodome (3-1) | 8-7 | |
| » W: Bob Knepper (2-0) L: Mario Soto (1-3) | Third | 4½ out |
| Tuesday, April 28 |
| » Defeated Padres (6-12), 11-2 | Riverfront Stadium (2-4) | 9-7 | |
| » W: Tom Seaver (2-1) L: Tim Lollar (1-1) | Second | 4 out |
| Wednesday, April 29 |
| » Defeated Padres (6-13), 8-5 | Riverfront Stadium (3-4) | 10-7 | Won 2 |
| » W: Paul Moskau (1-0) L: John Littlefield (0-2) S: Tom Hume (2) | Second | 3 out |
| Thursday, April 30 |
| » Defeated Padres (6-14), 4-3 | Riverfront Stadium (4-4) | 11-7 | Won 3 |
| » W: Mike LaCoss (1-2) L: Steve Mura (0-3) S: Tom Hume (3) | Second | 2½ out |
| Friday, May 1 |
| » Lost to Cardinals (10-3), 7-6 | Busch Stadium II (0-1) | 11-8 | |
| » W: Bob Forsch (2-1) L: Mario Soto (1-4) S: Bruce Sutter (5) | Second | 2½ out |
| Saturday, May 2 |
| » Lost to Cardinals (11-3), 7-3 | Busch Stadium II (0-2) | 11-9 | Lost 2 |
| » W: Bob Shirley (3-0) L: Bruce Berenyi (2-1) | Second | 3½ out |
| Sunday, May 3 |
| » Lost to Cardinals (12-3), 5-4 | Busch Stadium II (0-3) | 11-10 | Lost 3 |
| » W: Joe Edelen (1-0) L: Tom Hume (1-2) | Second | 4½ out |
| Wednesday, May 6 |
| » Defeated Pirates (8-9), 9-8 | Riverfront Stadium (5-4) | 12-10 | |
| » W: Tom Hume (2-2) L: Grant Jackson (1-2) | Second | 3½ out |
| Thursday, May 7 |
| » Lost to Pirates (9-9), 3-1 | Riverfront Stadium (5-5) | 12-11 | |
| » W: Rick Rhoden (4-0) L: Mario Soto (1-5) S: Enrique Romo (3) | Third | 5 out |
| » Lost to Pirates (10-9), 7-1 | Riverfront Stadium (5-6) | 12-12 | Lost 2 |
| » W: Eddie Solomon (2-1) L: Mike LaCoss (1-3) | Third | 5 out |
| Friday, May 8 |
| » Defeated Astros (12-15), 4-0 | Riverfront Stadium (6-6) | 13-12 | |
| » W: Tom Seaver (3-1) L: Don Sutton (2-4) | Third | 5 out |
| Saturday, May 9 |
| » Defeated Astros (12-16), 9-5 | Riverfront Stadium (7-6) | 14-12 | Won 2 |
| » W: Bruce Berenyi (3-1) L: Joaquin Andujar (1-2) | Second | 4 out |
| Sunday, May 10 |
| » Lost to Astros (13-16), 7-5 | Riverfront Stadium (7-7) | 14-13 | |
| » W: Joe Niekro (3-3) L: Frank Pastore (1-1) S: Frank LaCorte (2) | Third | 5 out |
| Monday, May 11 |
| » Lost to Astros (14-16), 5-0 | Riverfront Stadium (7-8) | 14-14 | Lost 2 |
| » W: Nolan Ryan (2-1) L: Mike LaCoss (1-4) | Third | 5½ out |
| Tuesday, May 12 |
| » Defeated Cubs (5-20), 2-1 | Riverfront Stadium (8-8) | 15-14 | |
| » W: Mario Soto (2-5) L: Dick Tidrow (1-4) | Third | 5½ out |
| Wednesday, May 13 |
| » Defeated Cubs (5-21), 8-3 | Riverfront Stadium (9-8) | 16-14 | Won 2 |
| » W: Tom Seaver (4-1) L: Mike Krukow (1-3) | Third | 5½ out |
| Thursday, May 14 |
| » Defeated Cubs (5-22), 6-1 | Riverfront Stadium (10-8) | 17-14 | Won 3 |
| » W: Bruce Berenyi (4-1) L: Rick Reuschel (1-4) | Second | 5½ out |
| Friday, May 15 |
| » Defeated Pirates (12-14), 4-1 | Three Rivers Stadium (1-0) | 18-14 | Won 4 |
| » W: Joe Price (2-0) L: Enrique Romo (0-2) S: Tom Hume (4) | Second | 5½ out |
| Saturday, May 16 |
| » Defeated Pirates (12-15), 4-0 | Three Rivers Stadium (2-0) | 19-14 | Won 5 |
| » W: Mike LaCoss (2-4) L: Rod Scurry (1-2) | Second | 5½ out |
| Sunday, May 17 |
| » Defeated Pirates (12-16), 4-3 | Three Rivers Stadium (3-0) | 20-14 | Won 6 |
| » W: Mario Soto (3-5) L: Eddie Solomon (2-3) | Second | 5½ out |
| Tuesday, May 19 |
| » Defeated Cubs (5-26), 5-0 | Wrigley Field (1-0) | 21-14 | Won 7 |
| » W: Tom Seaver (5-1) L: Rick Reuschel (1-5) S: Paul Moskau (2) | Second | 4 out |
| Wednesday, May 20 |
| » Defeated Cubs (5-27), 10-7 | Wrigley Field (2-0) | 22-14 | Won 8 |
| » W: Joe Price (3-0) L: Lee Smith (1-3) S: Tom Hume (5) | Second | 4 out |
| Thursday, May 21 |
| » Lost to Cubs (6-27), 5-1 | Wrigley Field (2-1) | 22-15 | |
| » W: Randy Martz (2-2) L: Frank Pastore (1-2) | Second | 4½ out |
| Friday, May 22 |
| » Lost to Dodgers (28-11), 4-2 | Riverfront Stadium (10-9) | 22-16 | Lost 2 |
| » W: Dave Stewart (2-0) L: Doug Bair (1-1) | Second | 5½ out |
| Saturday, May 23 |
| » Lost to Dodgers (29-11), 9-6 | Riverfront Stadium (10-10) | 22-17 | Lost 3 |
| » W: Dave Stewart (3-0) L: Paul Moskau (1-1) S: Bobby Castillo (4) | Second | 6½ out |
| Former Red Gene Green dies in St.Louis, MO at the age of 48. |
| Sunday, May 24 |
| » Defeated Dodgers (29-12), 3-2 | Riverfront Stadium (11-10) | 23-17 | |
| » W: Paul Moskau (2-1) L: Bob Welch (2-3) S: Joe Price (1) | Second | 6½ out |
| » Lost to Dodgers (30-12), 10-3 | Riverfront Stadium (11-11) | 23-18 | |
| » W: Bobby Castillo (1-4) L: Bruce Berenyi (4-2) | Second | 6½ out |
| Monday, May 25 |
| » Defeated Giants (23-22), 6-3 | Riverfront Stadium (12-11) | 24-18 | |
| » W: Geoff Combe (1-0) L: Al Holland (3-2) | Second | 6½ out |
| Wednesday, May 27 |
| » Defeated Giants (23-23), 3-2 | Riverfront Stadium (13-11) | 25-18 | Won 2 |
| » W: Mario Soto (4-5) L: Doyle Alexander (5-3) | Second | 5½ out |
| Thursday, May 28 |
| » Defeated Giants (23-24), 7-4 | Riverfront Stadium (14-11) | 26-18 | Won 3 |
| » W: Joe Price (4-0) L: Gary Lavelle (0-3) | Second | 4½ out |
| Friday, May 29 |
| » Lost to Dodgers (32-14), 5-2 | Dodger Stadium (0-1) | 26-19 | |
| » W: Bob Welch (3-3) L: Mike LaCoss (2-5) S: Steve Howe (5) | Second | 5½ out |
| Saturday, May 30 |
| » Defeated Dodgers (32-15), 9-1 | Dodger Stadium (1-1) | 27-19 | |
| » W: Frank Pastore (2-2) L: Burt Hooton (7-1) | Second | 4½ out |
| Sunday, May 31 |
| » Lost to Dodgers (33-15), 16-4 | Dodger Stadium (1-2) | 27-20 | |
| » W: Dave Goltz (1-0) L: Mario Soto (4-6) | Second | 5½ out |
| Future Red Ray Olmedo is born in Maracay, Venezuela. |
| Monday, June 1 |
| » Defeated Giants (25-26), 8-5 | Candlestick Park (1-0) | 28-20 | |
| » W: Tom Hume (3-2) L: Greg Minton (2-3) | Second | 5½ out |
| Tuesday, June 2 |
| » Lost to Giants (26-26), 15-7 | Candlestick Park (1-1) | 28-21 | |
| » W: Ed Whitson (2-5) L: Mike LaCoss (2-6) S: Al Holland (4) | Second | 5½ out |
| Wednesday, June 3 |
| » Defeated Giants (26-27), 6-2 | Candlestick Park (2-1) | 29-21 | |
| » W: Frank Pastore (3-2) L: Vida Blue (5-4) | Second | 4½ out |
| Friday, June 5 |
| » Defeated Expos (27-23), 6-3 | Riverfront Stadium (15-11) | 30-21 | Won 2 |
| » W: Mario Soto (5-6) L: Steve Rogers (6-4) | Second | 3½ out |
| Saturday, June 6 |
| » Defeated Expos (27-24), 9-3 | Riverfront Stadium (16-11) | 31-21 | Won 3 |
| » W: Tom Seaver (6-1) L: Charlie Lea (4-3) | Second | 2½ out |
| Sunday, June 7 |
| » Defeated Expos (27-25), 2-0 | Riverfront Stadium (17-11) | 32-21 | Won 4 |
| » W: Bruce Berenyi (5-2) L: Ray Burris (3-5) | Second | 2½ out |
| Tuesday, June 9 |
| » Defeated Mets (17-32), 8-4 | Shea Stadium (1-0) | 33-21 | Won 5 |
| » W: Tom Hume (4-2) L: Pete Falcone (1-3) | Second | 1½ out |
| Wednesday, June 10 |
| » Defeated Mets (17-33), 2-0 | Shea Stadium (2-0) | 34-21 | Won 6 |
| » W: Mario Soto (6-6) L: Randy Jones (1-7) | Second | 1½ out |
| Thursday, June 11 |
| » Defeated Mets (17-34), 5-2 | Shea Stadium (3-0) | 35-21 | Won 7 |
| » W: Tom Seaver (7-1) L: Pat Zachry (5-7) | Second | ½ out |
| » Major-league debuts: Ray Searage (Mets) |
| Wednesday, July 8 |
| Former Red Bill Hallahan dies in Binghamton, NY at the age of 79. |
| Monday, August 10 |
| » Lost to Dodgers (37-21), 4-0 | Dodger Stadium (1-3) | 35-22 | |
| » W: Jerry Reuss (6-2) L: Frank Pastore (3-3) S: Steve Howe (6) | Second | 1½ out |
| Tuesday, August 11 |
| » Defeated Dodgers (37-22), 7-6 | Dodger Stadium (2-3) | 36-22 | |
| » W: Scott Brown (1-0) L: Terry Forster (0-1) S: Tom Hume (6) | Second | ½ out |
| Wednesday, August 12 |
| » Lost to Dodgers (38-22), 8-5 | Dodger Stadium (2-4) | 36-23 | |
| » W: Dave Stewart (4-1) L: Tom Seaver (7-2) S: Steve Howe (7) | Second | 1½ out |
| Friday, August 14 |
| » Lost to Giants (29-34), 4-0 | Riverfront Stadium (17-12) | 36-24 | Lost 2 |
| » W: Ed Whitson (3-5) L: Bruce Berenyi (5-3) | Second | 1½ out |
| » Defeated Giants (29-35), 7-6 | Riverfront Stadium (18-12) | 37-24 | |
| » W: Tom Hume (5-2) L: Al Holland (3-4) | Second | 1½ out |
| » Major-league debuts: Bob Brenly (Giants) |
| Saturday, August 15 |
| » Lost to Giants (30-35), 5-2 | Riverfront Stadium (18-13) | 37-25 | |
| » W: Doyle Alexander (6-4) L: Frank Pastore (3-4) S: Greg Minton (11) | Second | 1½ out |
| Sunday, August 16 |
| » Defeated Giants (30-36), 2-1 | Riverfront Stadium (19-13) | 38-25 | |
| » W: Mario Soto (7-6) L: Tom Griffin (5-6) S: Tom Hume (7) | Second | 1½ out |
| Tuesday, August 18 |
| » Defeated Phillies (36-27), 3-1 | Riverfront Stadium (20-13) | 39-25 | Won 2 |
| » W: Tom Seaver (8-2) L: Steve Carlton (9-3) S: Tom Hume (8) | Second | 1 out |
| Wednesday, August 19 |
| » Defeated Phillies (36-28), 6-3 | Riverfront Stadium (21-13) | 40-25 | Won 3 |
| » W: Tom Hume (6-2) L: Sparky Lyle (5-2) | First | -- |
| Friday, August 21 |
| » Defeated Mets (23-39), 2-0 | Riverfront Stadium (22-13) | 41-25 | Won 4 |
| » W: Mario Soto (8-6) L: Pat Zachry (6-8) | First | -- |
| Saturday, August 22 |
| » Lost to Mets (24-39), 7-4 | Riverfront Stadium (22-14) | 41-26 | |
| » W: Dan Boitano (1-0) L: Frank Pastore (3-5) S: Neil Allen (11) | Second | 1 out |
| Sunday, August 23 |
| » Lost to Mets (25-39), 3-2 | Riverfront Stadium (22-15) | 41-27 | Lost 2 |
| » W: Neil Allen (5-3) L: Tom Hume (6-3) | Second | 1 out |
| Monday, August 24 |
| » Defeated Mets (25-40), 2-0 | Riverfront Stadium (23-15) | 42-27 | |
| » W: Bruce Berenyi (6-3) L: Mike Scott (3-7) | Second | 1 out |
| Tuesday, August 25 |
| » Lost to Expos (37-31), 9-1 | Stade Olympique (0-1) | 42-28 | |
| » W: Scott Sanderson (7-4) L: Mike LaCoss (2-7) | Second | 2 out |
| Wednesday, August 26 |
| » Lost to Expos (38-31), 6-0 | Stade Olympique (0-2) | 42-29 | Lost 2 |
| » W: Bill Gullickson (4-6) L: Mario Soto (8-7) | Second | 3 out |
| Thursday, August 27 |
| » Lost to Expos (39-31), 12-0 | Stade Olympique (0-3) | 42-30 | Lost 3 |
| » W: Ray Burris (6-5) L: Frank Pastore (3-6) | Second | 4 out |
| Friday, August 28 |
| » Defeated Mets (27-42), 5-2 | Shea Stadium (4-0) | 43-30 | |
| » W: Tom Seaver (9-2) L: Neil Allen (5-4) | Second | 4 out |
| Saturday, August 29 |
| » Lost to Mets (28-42), 3-2 | Shea Stadium (4-1) | 43-31 | |
| » W: Mike Scott (4-7) L: Bruce Berenyi (6-4) S: Neil Allen (13) | Second | 4 out |
| Sunday, August 30 |
| » Defeated Mets (28-43), 6-3 | Shea Stadium (5-1) | 44-31 | |
| » W: Mike LaCoss (3-7) L: Greg Harris (2-4) | Second | 3 out |
| Monday, August 31 |
| » Defeated Expos (41-33), 9-8 | Riverfront Stadium (24-15) | 45-31 | Won 2 |
| » W: Doug Bair (2-1) L: Bill Lee (2-4) | Second | 2 out |
| Tuesday, September 1 |
| » Lost to Expos (42-33), 4-3 | Riverfront Stadium (24-16) | 45-32 | |
| » W: Charlie Lea (5-4) L: Joe Price (4-1) S: Jeff Reardon (4) | Second | 3 out |
| Wednesday, September 2 |
| » Defeated Expos (42-34), 7-0 | Riverfront Stadium (25-16) | 46-32 | |
| » W: Tom Seaver (10-2) L: Stan Bahnsen (2-1) | Second | 3 out |
| » Major-league debuts: Tom Gorman (Expos) |
| Thursday, September 3 |
| » Defeated Phillies (42-36), 9-3 | Veteran's Stadium (1-0) | 47-32 | Won 2 |
| » W: Bruce Berenyi (7-4) L: Mark Davis (0-3) | Second | 2 out |
| » Major-league debuts: Len Matuszek (Phillies) |
| Friday, September 4 |
| » Lost to Phillies (43-36), 7-6 | Veteran's Stadium (1-1) | 47-33 | |
| » W: Sparky Lyle (7-4) L: Doug Bair (2-2) S: Tug McGraw (9) | Second | 2 out |
| Saturday, September 5 |
| » Lost to Phillies (44-36), 5-4 | Veteran's Stadium (1-2) | 47-34 | Lost 2 |
| » W: Ron Reed (3-1) L: Mario Soto (8-8) | Second | 3 out |
| Sunday, September 6 |
| » Defeated Phillies (44-37), 5-4 | Veteran's Stadium (2-2) | 48-34 | |
| » W: Tom Hume (7-3) L: Sparky Lyle (7-5) S: Joe Price (2) | Second | 3 out |
| Monday, September 7 |
| » Defeated Padres (31-54), 8-7 | Riverfront Stadium (26-16) | 49-34 | Won 2 |
| » W: Tom Seaver (11-2) L: Eric Show (0-1) S: Joe Price (3) | Second | 3 out |
| Tuesday, September 8 |
| » Lost to Padres (32-54), 6-1 | Riverfront Stadium (26-17) | 49-35 | |
| » W: Juan Eichelberger (7-6) L: Bruce Berenyi (7-5) | Second | 4 out |
| Wednesday, September 9 |
| » Defeated Padres (32-55), 5-4 | Riverfront Stadium (27-17) | 50-35 | |
| » W: Tom Hume (8-3) L: John Urrea (2-2) | Second | 3 out |
| Friday, September 11 |
| » Defeated Dodgers (54-34), 3-2 | Riverfront Stadium (28-17) | 51-35 | Won 2 |
| » W: Joe Price (5-1) L: Alejandro Pena (1-1) | Second | 2 out |
| Saturday, September 12 |
| » Defeated Dodgers (54-35), 6-5 | Riverfront Stadium (29-17) | 52-35 | Won 3 |
| » W: Mike LaCoss (4-7) L: Ted Power (0-1) | Second | 1 out |
| Sunday, September 13 |
| » Lost to Dodgers (55-35), 4-2 | Riverfront Stadium (29-18) | 52-36 | |
| » W: Bobby Castillo (2-4) L: Frank Pastore (3-7) S: Dave Stewart (5) | Second | 2 out |
| Monday, September 14 |
| » Defeated Astros (50-41), 4-2 | Astrodome (4-1) | 53-36 | |
| » W: Bruce Berenyi (8-5) L: Vern Ruhle (3-4) | Second | 2 out |
| Tuesday, September 15 |
| » Defeated Astros (50-42), 4-0 | Astrodome (5-1) | 54-36 | Won 2 |
| » W: Charlie Leibrandt (1-0) L: Nolan Ryan (8-5) | Second | 1 out |
| Wednesday, September 16 |
| » Lost to Giants (47-47), 12-7 | Candlestick Park (2-2) | 54-37 | |
| » W: Fred Breining (4-2) L: Mario Soto (8-9) | Second | 2 out |
| Thursday, September 17 |
| » Defeated Giants (47-48), 1-0 | Candlestick Park (3-2) | 55-37 | |
| » W: Tom Seaver (12-2) L: Al Holland (6-5) S: Tom Hume (9) | Second | 2 out |
| Friday, September 18 |
| » Defeated Dodgers (58-37), 5-4 | Dodger Stadium (3-4) | 56-37 | Won 2 |
| » W: Joe Price (6-1) L: Dave Stewart (4-3) S: Tom Hume (10) | Second | 1 out |
| Saturday, September 19 |
| » Defeated Dodgers (58-38), 7-3 | Dodger Stadium (4-4) | 57-37 | Won 3 |
| » W: Joe Edelen (2-0) L: Burt Hooton (10-6) | First | -- |
| Sunday, September 20 |
| » Defeated Dodgers (58-39), 5-1 | Dodger Stadium (5-4) | 58-37 | Won 4 |
| » W: Mario Soto (9-9) L: Ted Power (1-2) | First | -- |
| Monday, September 21 |
| » Lost to Padres (36-62), 6-0 | San Diego/Jack Murphy Stadium (3-1) | 58-38 | |
| » W: Chris Welsh (6-6) L: Charlie Leibrandt (1-1) | First | -- |
| Tuesday, September 22 |
| » Defeated Padres (36-63), 3-2 | San Diego/Jack Murphy Stadium (4-1) | 59-38 | |
| » W: Tom Seaver (13-2) L: Juan Eichelberger (8-7) S: Tom Hume (11) | First | -- |
| Wednesday, September 23 |
| » Defeated Padres (36-64), 5-1 | San Diego/Jack Murphy Stadium (5-1) | 60-38 | Won 2 |
| » W: Frank Pastore (4-7) L: Rick Wise (3-8) S: Joe Price (4) | First | -- |
| Friday, September 25 |
| » Defeated Braves (46-51), 10-2 | Atlanta-Fulton County Stadium (2-2) | 61-38 | Won 3 |
| » W: Mario Soto (10-9) L: Tommy Boggs (3-12) | First | -- |
| » Major-league debuts: Paul Runge (Braves) |
| Saturday, September 26 |
| » Defeated Braves (46-52), 2-0 | Atlanta-Fulton County Stadium (3-2) | 62-38 | Won 4 |
| » W: Bruce Berenyi (9-5) L: Phil Niekro (7-6) S: Tom Hume (12) | First | -- |
| Sunday, September 27 |
| » Defeated Braves (46-53), 4-2 | Atlanta-Fulton County Stadium (4-2) | 63-38 | Won 5 |
| » W: Tom Seaver (14-2) L: Gaylord Perry (7-9) S: Mike LaCoss (1) | First | -- |
| Monday, September 28 |
| » Lost to Giants (54-51), 4-0 | Riverfront Stadium (29-19) | 63-39 | |
| » W: Alan Hargesheimer (1-1) L: Frank Pastore (4-8) | First | -- |
| Tuesday, September 29 |
| » Defeated Giants (54-52), 4-3 | Riverfront Stadium (30-19) | 64-39 | |
| » W: Tom Hume (9-3) L: Greg Minton (4-5) | First | -- |
| Wednesday, September 30 |
| » Defeated Astros (59-47), 5-2 | Riverfront Stadium (31-19) | 65-39 | Won 2 |
| » W: Mario Soto (11-9) L: Vern Ruhle (4-6) S: Tom Hume (13) | First | -- |
| Thursday, October 1 |
| » Lost to Astros (60-47), 8-1 | Riverfront Stadium (31-20) | 65-40 | |
| » W: Nolan Ryan (11-5) L: Bruce Berenyi (9-6) | First | -- |
| Friday, October 2 |
| » Lost to Braves (49-55), 11-5 | Riverfront Stadium (31-21) | 65-41 | Lost 2 |
| » W: Gaylord Perry (8-9) L: Frank Pastore (4-9) | First | -- |
| Saturday, October 3 |
| » Lost to Braves (50-55), 4-3 | Riverfront Stadium (31-22) | 65-42 | Lost 3 |
| » W: Rick Mahler (8-6) L: Tom Hume (9-4) S: Rick Camp (17) | First | -- |
| Sunday, October 4 |
| » Defeated Braves (50-56), 3-0 | Riverfront Stadium (32-22) | 66-42 | |
| » W: Mario Soto (12-9) L: Tommy Boggs (3-13) | First | -- |
| Tuesday, December 1 |
| Former Red Tony Piet dies in Hinsdale, IL at the age of 75. |
Game information provided by Retrosheet (www.retrosheet.org) |