| Thursday, March 19 |
| Future Pirate Jose Castillo is born in Las Mercedes, Venezuela. |
| Thursday, April 9 |
| » Lost to Expos (1-0), 6-5 | Three Rivers Stadium (0-1) | 0-1 | |
| » W: Woodie Fryman (1-0) L: Kent Tekulve (0-1) | Third | 1 out |
| Friday, April 10 |
| » Major-league debuts: Rufino Linares (Braves) |
| Sunday, April 12 |
| » Defeated Expos (1-1), 3-2 | Three Rivers Stadium (1-1) | 1-1 | |
| » W: Rick Rhoden (1-0) L: Ray Burris (0-1) S: Enrique Romo (1) | Second | ½ out |
| Monday, April 13 |
| » Lost to Phillies (2-2), 5-1 | Veteran's Stadium (0-1) | 1-2 | |
| » W: Steve Carlton (1-0) L: John Candelaria (0-1) | Fourth | 1 out |
| Wednesday, April 15 |
| » Lost to Phillies (3-2), 4-3 | Veteran's Stadium (0-2) | 1-3 | Lost 2 |
| » W: Tug McGraw (1-0) L: Enrique Romo (0-1) | Fifth | 2 out |
| Thursday, April 16 |
| » Lost to Phillies (4-2), 5-3 | Veteran's Stadium (0-3) | 1-4 | Lost 3 |
| » W: Dick Ruthven (2-0) L: Don Robinson (0-1) S: Tug McGraw (1) | Fifth | 2½ out |
| Friday, April 17 |
| » Defeated Astros (2-5), 4-3 | Astrodome (1-0) | 2-4 | |
| » W: Rick Rhoden (2-0) L: Don Sutton (0-2) S: Enrique Romo (2) | Fourth | 2 out |
| Saturday, April 18 |
| » Defeated Astros (2-6), 6-3 | Astrodome (2-0) | 3-4 | Won 2 |
| » W: Grant Jackson (1-0) L: Dave Smith (0-1) | Fifth | 2 out |
| Sunday, April 19 |
| » Defeated Astros (2-7), 2-0 | Astrodome (3-0) | 4-4 | Won 3 |
| » W: Rod Scurry (1-0) L: Joe Niekro (1-2) S: Eddie Solomon (1) | Fourth | 2½ out |
| Wednesday, April 22 |
| » Tied Mets, 2-2 | Three Rivers Stadium (1-1) | 4-4 | |
| » Starters: Mike Scott vs Rick Rhoden | Fourth | 3 out |
| Saturday, April 25 |
| » Lost to Cardinals (8-2), 5-1 | Three Rivers Stadium (1-2) | 4-5 | |
| » W: Bob Shirley (2-0) L: John Candelaria (0-2) | Fourth | 4 out |
| Sunday, April 26 |
| » Lost to Cardinals (9-2), 3-2 | Three Rivers Stadium (1-3) | 4-6 | Lost 2 |
| » W: Jim Kaat (1-0) L: Grant Jackson (1-1) S: Bruce Sutter (4) | Fourth | 5½ out |
| Tuesday, April 28 |
| » Defeated Mets (4-8), 8-0 | Shea Stadium (1-0) | 5-6 | |
| » W: Rick Rhoden (3-0) L: Mike Scott (0-2) | Fourth | 4 out |
| Wednesday, April 29 |
| » Defeated Mets (4-9), 10-0 | Shea Stadium (2-0) | 6-6 | Won 2 |
| » W: Jim Bibby (1-0) L: Dave Roberts (0-1) | Fourth | 4 out |
| Thursday, April 30 |
| » Defeated Mets (4-10), 7-4 | Shea Stadium (3-0) | 7-6 | Won 3 |
| » W: John Candelaria (1-2) L: Randy Jones (0-3) S: Grant Jackson (1) | Fourth | 3½ out |
| Friday, May 1 |
| » Lost to Astros (8-12), 5-3 | Three Rivers Stadium (1-4) | 7-7 | |
| » W: Joe Sambito (1-1) L: Eddie Solomon (0-1) | Fourth | 3½ out |
| Saturday, May 2 |
| » Defeated Astros (8-13), 5-4 | Three Rivers Stadium (2-4) | 8-7 | |
| » W: Eddie Solomon (1-1) L: Dave Smith (0-3) | Fourth | 3½ out |
| Sunday, May 3 |
| » Lost to Astros (9-13), 3-1 | Three Rivers Stadium (2-5) | 8-8 | |
| » W: Don Sutton (2-3) L: Jim Bibby (1-1) S: Dave Smith (2) | Fourth | 4½ out |
| Wednesday, May 6 |
| » Lost to Reds (12-10), 9-8 | Riverfront Stadium (0-1) | 8-9 | Lost 2 |
| » W: Tom Hume (2-2) L: Grant Jackson (1-2) | Fourth | 4½ out |
| Thursday, May 7 |
| » Defeated Reds (12-11), 3-1 | Riverfront Stadium (1-1) | 9-9 | |
| » W: Rick Rhoden (4-0) L: Mario Soto (1-5) S: Enrique Romo (3) | Fourth | 4 out |
| » Defeated Reds (12-12), 7-1 | Riverfront Stadium (2-1) | 10-9 | Won 2 |
| » W: Eddie Solomon (2-1) L: Mike LaCoss (1-3) | Fourth | 4 out |
| Friday, May 8 |
| » Lost to Cardinals (14-6), 5-4 | Busch Stadium II (0-1) | 10-10 | |
| » W: Bob Shirley (4-0) L: Jim Bibby (1-2) S: Jim Kaat (1) | Fourth | 4 out |
| Saturday, May 9 |
| » Lost to Cardinals (15-6), 13-0 | Busch Stadium II (0-2) | 10-11 | Lost 2 |
| » W: Andy Rincon (3-1) L: Rod Scurry (1-1) | Fourth | 5 out |
| Sunday, May 10 |
| » Defeated Cardinals (15-7), 8-2 | Busch Stadium II (1-2) | 11-11 | |
| » W: John Candelaria (2-2) L: Lary Sorensen (4-1) S: Enrique Romo (4) | Fourth | 4 out |
| Monday, May 11 |
| » Lost to Braves (16-13), 3-2 | Atlanta-Fulton County Stadium (0-1) | 11-12 | |
| » W: Rick Mahler (2-0) L: Kent Tekulve (0-2) | Fourth | 4½ out |
| Tuesday, May 12 |
| » Lost to Braves (17-13), 2-0 | Atlanta-Fulton County Stadium (0-2) | 11-13 | Lost 2 |
| » W: Phil Niekro (2-1) L: Eddie Solomon (2-2) | Fourth | 5½ out |
| Wednesday, May 13 |
| » Defeated Braves (17-14), 7-5 | Atlanta-Fulton County Stadium (1-2) | 12-13 | |
| » W: Victor Cruz (1-0) L: Tommy Boggs (1-5) S: Rod Scurry (1) | Fourth | 4½ out |
| Friday, May 15 |
| » Lost to Reds (18-14), 4-1 | Three Rivers Stadium (2-6) | 12-14 | |
| » W: Joe Price (2-0) L: Enrique Romo (0-2) S: Tom Hume (4) | Fourth | 5 out |
| Saturday, May 16 |
| » Lost to Reds (19-14), 4-0 | Three Rivers Stadium (2-7) | 12-15 | Lost 2 |
| » W: Mike LaCoss (2-4) L: Rod Scurry (1-2) | Fourth | 6 out |
| Sunday, May 17 |
| » Lost to Reds (20-14), 4-3 | Three Rivers Stadium (2-8) | 12-16 | Lost 3 |
| » W: Mario Soto (3-5) L: Eddie Solomon (2-3) | Fourth | 7 out |
| Tuesday, May 19 |
| » Defeated Braves (18-17), 5-0 | Three Rivers Stadium (3-8) | 13-16 | |
| » W: Jim Bibby (2-2) L: Phil Niekro (2-2) | Fourth | 7 out |
| Wednesday, May 20 |
| » Defeated Braves (18-18), 6-1 | Three Rivers Stadium (4-8) | 14-16 | Won 2 |
| » W: Rick Rhoden (5-0) L: Bob Walk (1-3) S: Enrique Romo (5) | Fourth | 6 out |
| Friday, May 22 |
| » Defeated Phillies (23-15), 3-1 | Three Rivers Stadium (5-8) | 15-16 | Won 3 |
| » W: Pascual Perez (1-0) L: Larry Christenson (1-4) | Fourth | 5½ out |
| Saturday, May 23 |
| » Lost to Phillies (24-15), 6-4 | Three Rivers Stadium (5-9) | 15-17 | |
| » W: Mike Proly (1-0) L: Kent Tekulve (0-3) S: Ron Reed (2) | Fourth | 6½ out |
| Sunday, May 24 |
| » Defeated Phillies (24-16), 7-1 | Three Rivers Stadium (6-9) | 16-17 | |
| » W: Jim Bibby (3-2) L: Marty Bystrom (3-3) S: Victor Cruz (1) | Fourth | 5½ out |
| Monday, May 25 |
| » Lost to Cubs (9-28), 10-9 | Wrigley Field (0-1) | 16-18 | |
| » W: Dick Tidrow (2-4) L: Victor Cruz (1-1) | Fourth | 5½ out |
| Tuesday, May 26 |
| » Defeated Cubs (9-29), 6-4 | Wrigley Field (1-1) | 17-18 | |
| » W: Kent Tekulve (1-3) L: Mike Krukow (1-6) S: Enrique Romo (6) | Fourth | 4½ out |
| Wednesday, May 27 |
| » Defeated Cubs (9-30), 3-2 | Wrigley Field (2-1) | 18-18 | Won 2 |
| » W: Pascual Perez (2-0) L: Rick Reuschel (2-6) | Fourth | 3½ out |
| Thursday, May 28 |
| » Defeated Cubs (9-31), 9-4 | Wrigley Field (3-1) | 19-18 | Won 3 |
| » W: Eddie Solomon (3-3) L: Bill Caudill (1-4) | Fourth | 3 out |
| Friday, May 29 |
| » Lost to Expos (25-18), 3-2 | Stade Olympique (0-1) | 19-19 | |
| » W: Scott Sanderson (5-2) L: Jim Bibby (3-3) S: Bill Lee (5) | Fourth | 4 out |
| Saturday, May 30 |
| » Defeated Expos (25-19), 3-2 | Stade Olympique (1-1) | 20-19 | |
| » W: Rick Rhoden (6-0) L: Bill Gullickson (2-5) | Fourth | 3 out |
| Sunday, May 31 |
| » Lost to Expos (26-19), 5-1 | Stade Olympique (1-2) | 20-20 | |
| » W: Steve Rogers (6-3) L: Pascual Perez (2-1) | Fourth | 4 out |
| Tuesday, June 2 |
| » Defeated Cubs (10-34), 16-3 | Three Rivers Stadium (7-9) | 21-20 | |
| » W: Eddie Solomon (4-3) L: Bill Caudill (1-5) | Fourth | 4½ out |
| Wednesday, June 3 |
| » Defeated Cubs (10-35), 3-2 | Three Rivers Stadium (8-9) | 22-20 | Won 2 |
| » W: Jim Bibby (4-3) L: Randy Martz (2-4) S: Enrique Romo (7) | Fourth | 3½ out |
| Thursday, June 4 |
| » Defeated Cubs (10-36), 5-4 | Three Rivers Stadium (9-9) | 23-20 | Won 3 |
| » W: Kent Tekulve (2-3) L: Lynn McGlothen (0-3) | Fourth | 3 out |
| Friday, June 5 |
| » Lost to Giants (27-27), 5-3 | Three Rivers Stadium (9-10) | 23-21 | |
| » W: Fred Breining (2-1) L: Enrique Romo (0-3) S: Gary Lavelle (4) | Fourth | 3½ out |
| Saturday, June 6 |
| » Defeated Giants (27-28), 7-6 | Three Rivers Stadium (10-10) | 24-21 | |
| » W: Rod Scurry (2-2) L: Tom Griffin (4-4) S: Kent Tekulve (1) | Third | 3½ out |
| Sunday, June 7 |
| » Defeated Giants (27-29), 3-2 | Three Rivers Stadium (11-10) | 25-21 | Won 2 |
| » W: Eddie Solomon (5-3) L: Vida Blue (5-5) S: Enrique Romo (8) | Third | 3 out |
| Tuesday, June 9 |
| » Lost to Padres (22-33), 7-4 | Three Rivers Stadium (11-11) | 25-22 | |
| » W: Steve Mura (4-7) L: Rick Rhoden (6-1) S: Gary Lucas (9) | Third | 4½ out |
| Wednesday, June 10 |
| » Lost to Padres (23-33), 3-2 | Three Rivers Stadium (11-12) | 25-23 | Lost 2 |
| » W: Juan Eichelberger (6-3) L: Pascual Perez (2-2) S: Gary Lucas (10) | Fourth | 5½ out |
| Monday, August 10 |
| » Lost to Expos (31-25), 3-1 | Stade Olympique (1-3) | 25-24 | Lost 3 |
| » W: Bill Lee (2-2) L: Pascual Perez (2-3) | Fourth | 5 out |
| Tuesday, August 11 |
| » Defeated Expos (31-26), 6-3 | Stade Olympique (2-3) | 26-24 | |
| » W: Kent Tekulve (3-3) L: Woodie Fryman (3-2) | Fourth | 5½ out |
| Wednesday, August 12 |
| » Lost to Expos (32-26), 3-2 | Three Rivers Stadium (11-13) | 26-25 | |
| » W: Ray Burris (4-5) L: Eddie Solomon (5-4) S: Bill Lee (6) | Fourth | 5 out |
| Thursday, August 13 |
| » Lost to Expos (33-26), 7-2 | Three Rivers Stadium (11-14) | 26-26 | Lost 2 |
| » W: Steve Rogers (8-4) L: Luis Tiant (0-1) | Fourth | 6 out |
| Saturday, August 15 |
| » Lost to Cubs (17-40), 4-3 | Wrigley Field (3-2) | 26-27 | Lost 3 |
| » W: Randy Martz (4-5) L: Rod Scurry (2-3) | Fourth | 7 out |
| Sunday, August 16 |
| » Defeated Cubs (17-41), 4-3 | Wrigley Field (4-2) | 27-27 | |
| » W: Kent Tekulve (4-3) L: Lee Smith (1-5) S: Grant Jackson (2) | Fourth | 7 out |
| » Lost to Cubs (18-41), 6-4 | Wrigley Field (4-3) | 27-28 | |
| » W: Jay Howell (1-0) L: Pascual Perez (2-4) S: Randy Martz (1) | Fourth | 7 out |
| Monday, August 17 |
| » Lost to Giants (31-36), 5-1 | Three Rivers Stadium (11-15) | 27-29 | Lost 2 |
| » W: Greg Minton (3-3) L: Rod Scurry (2-4) | Fourth | 8 out |
| Tuesday, August 18 |
| » Lost to Giants (32-36), 4-2 | Three Rivers Stadium (11-16) | 27-30 | Lost 3 |
| » W: Ed Whitson (4-5) L: Luis Tiant (0-2) S: Greg Minton (12) | Fourth | 8 out |
| Wednesday, August 19 |
| » Defeated Giants (32-37), 7-3 | Three Rivers Stadium (12-16) | 28-30 | |
| » W: Odell Jones (1-0) L: Doyle Alexander (6-5) S: Grant Jackson (3) | Fourth | 8 out |
| Thursday, August 20 |
| » Major-league debuts: Brett Butler (Braves) |
| Friday, August 21 |
| » Defeated Padres (25-42), 4-2 | Three Rivers Stadium (13-16) | 29-30 | Won 2 |
| » W: Rick Rhoden (7-1) L: Steve Mura (4-10) S: Grant Jackson (4) | Fourth | 6½ out |
| » Defeated Padres (25-43), 3-2 | Three Rivers Stadium (14-16) | 30-30 | Won 3 |
| » W: Jim Bibby (5-3) L: Tim Lollar (1-6) S: Kent Tekulve (2) | Fourth | 6½ out |
| Saturday, August 22 |
| » Lost to Padres (26-43), 7-6 | Three Rivers Stadium (14-17) | 30-31 | |
| » W: John Curtis (2-4) L: Kent Tekulve (4-4) S: Gary Lucas (11) | Fourth | 6½ out |
| Sunday, August 23 |
| » Defeated Padres (26-44), 5-2 | Three Rivers Stadium (15-17) | 31-31 | |
| » W: Rod Scurry (3-4) L: Chris Welsh (5-5) S: Enrique Romo (9) | Fourth | 6½ out |
| Monday, August 24 |
| » Lost to Dodgers (44-27), 3-0 | Three Rivers Stadium (15-18) | 31-32 | |
| » W: Burt Hooton (9-4) L: Odell Jones (1-1) | Fourth | 7½ out |
| Tuesday, August 25 |
| » Lost to Dodgers (45-27), 9-7 | Three Rivers Stadium (15-19) | 31-33 | Lost 2 |
| » W: Alejandro Pena (1-0) L: Kent Tekulve (4-5) S: Tom Niedenfuer (1) | Fourth | 7½ out |
| Wednesday, August 26 |
| » Lost to Dodgers (46-27), 16-6 | Three Rivers Stadium (15-20) | 31-34 | Lost 3 |
| » W: Jerry Reuss (8-3) L: Rick Rhoden (7-2) | Fourth | 8½ out |
| Thursday, August 27 |
| » Lost to Giants (36-40), 5-4 | Candlestick Park (0-1) | 31-35 | Lost 4 |
| » W: Al Holland (4-4) L: Don Robinson (0-2) | Fourth | 9½ out |
| Friday, August 28 |
| » Lost to Giants (37-40), 5-1 | Candlestick Park (0-2) | 31-36 | Lost 5 |
| » W: Ed Whitson (5-5) L: Rod Scurry (3-5) | Third | 10 out |
| Saturday, August 29 |
| » Lost to Giants (38-40), 8-3 | Candlestick Park (0-3) | 31-37 | Lost 6 |
| » W: Doyle Alexander (7-5) L: Luis Tiant (0-3) | Fourth | 11½ out |
| Sunday, August 30 |
| » Lost to Giants (39-40), 5-0 | Candlestick Park (0-4) | 31-38 | Lost 7 |
| » W: Tom Griffin (7-6) L: Pascual Perez (2-5) | Fourth | 11½ out |
| Monday, August 31 |
| » Defeated Dodgers (48-30), 5-4 | Dodger Stadium (1-0) | 32-38 | |
| » W: Odell Jones (2-1) L: Dave Stewart (4-2) S: Don Robinson (1) | Fourth | 11 out |
| Tuesday, September 1 |
| » Lost to Dodgers (49-30), 3-2 | Dodger Stadium (1-1) | 32-39 | |
| » W: Tom Niedenfuer (2-0) L: Odell Jones (2-2) | Fourth | 11 out |
| Wednesday, September 2 |
| » Lost to Dodgers (50-30), 6-2 | Dodger Stadium (1-2) | 32-40 | Lost 2 |
| » W: Bob Welch (6-5) L: Bob Long (0-1) S: Alejandro Pena (2) | Fourth | 12 out |
| » Major-league debuts: Ron Roenicke (Dodgers) Johnny Ray (Pirates) |
| Thursday, September 3 |
| » Defeated Padres (30-51), 7-3 | San Diego/Jack Murphy Stadium (1-0) | 33-40 | |
| » W: Luis Tiant (1-3) L: Juan Eichelberger (6-6) S: Rod Scurry (2) | Fourth | 12 out |
| Friday, September 4 |
| » Lost to Padres (31-51), 5-4 | San Diego/Jack Murphy Stadium (1-1) | 33-41 | |
| » W: John Littlefield (2-3) L: Don Robinson (0-3) S: Eric Show (1) | Fourth | 13 out |
| » Major-league debuts: Alan Wiggins (Padres) |
| Saturday, September 5 |
| » Defeated Padres (31-52), 2-1 | San Diego/Jack Murphy Stadium (2-1) | 34-41 | |
| » W: Rick Rhoden (8-2) L: Steve Mura (5-11) S: Rod Scurry (3) | Fourth | 12 out |
| Sunday, September 6 |
| » Defeated Padres (31-53), 9-5 | San Diego/Jack Murphy Stadium (3-1) | 35-41 | Won 2 |
| » W: Eddie Solomon (6-4) L: Rick Wise (3-6) S: Don Robinson (2) | Fourth | 11 out |
| Monday, September 7 |
| » Defeated Mets (30-48), 2-1 | Three Rivers Stadium (16-20) | 36-41 | Won 3 |
| » W: Odell Jones (3-2) L: Neil Allen (5-5) S: Rod Scurry (4) | Fourth | 9½ out |
| » Defeated Mets (30-49), 5-4 | Three Rivers Stadium (17-20) | 37-41 | Won 4 |
| » W: Bob Long (1-1) L: Dan Boitano (1-1) S: Mark Lee (1) | Fourth | 9½ out |
| Tuesday, September 8 |
| » Lost to Mets (31-49), 3-1 | Three Rivers Stadium (17-21) | 37-42 | |
| » W: Ed Lynch (3-3) L: Luis Tiant (1-4) S: Neil Allen (16) | Fourth | 9½ out |
| Wednesday, September 9 |
| » Lost to Mets (32-49), 5-3 | Three Rivers Stadium (17-22) | 37-43 | Lost 2 |
| » W: Terry Leach (1-0) L: Pascual Perez (2-6) S: Ray Searage (1) | Fourth | 9½ out |
| Friday, September 11 |
| » Lost to Phillies (47-38), 8-0 | Three Rivers Stadium (17-23) | 37-44 | Lost 3 |
| » W: Steve Carlton (12-3) L: Rick Rhoden (8-3) | Fourth | 10½ out |
| » Major-league debuts: Jerry Reed (Phillies) |
| Saturday, September 12 |
| » Defeated Phillies (47-39), 6-2 | Three Rivers Stadium (18-23) | 38-44 | |
| » W: Eddie Solomon (7-4) L: Dickie Noles (0-2) S: Rod Scurry (5) | Fourth | 10½ out |
| Sunday, September 13 |
| » Defeated Phillies (47-40), 3-2 | Three Rivers Stadium (19-23) | 39-44 | Won 2 |
| » W: Odell Jones (4-2) L: Ron Reed (4-2) S: Kent Tekulve (3) | Fourth | 10½ out |
| Tuesday, September 15 |
| » Defeated Cubs (31-55), 8-2 | Wrigley Field (5-3) | 40-44 | Won 3 |
| » W: Luis Tiant (2-4) L: Mike Griffin (2-3) | Fourth | 10 out |
| Friday, September 18 |
| » Defeated Phillies (49-42), 7-6 | Veteran's Stadium (1-3) | 41-44 | Won 4 |
| » W: Rod Scurry (4-5) L: Ron Reed (4-3) S: Mark Lee (2) | Fourth | 9½ out |
| Saturday, September 19 |
| » Lost to Phillies (50-42), 8-2 | Veteran's Stadium (1-4) | 41-45 | |
| » W: Dan Larson (2-0) L: Odell Jones (4-3) S: Larry Christenson (1) | Fourth | 9½ out |
| Sunday, September 20 |
| » Lost to Phillies (51-42), 5-4 | Veteran's Stadium (1-5) | 41-46 | Lost 2 |
| » W: Sparky Lyle (8-5) L: Eddie Solomon (7-5) | Fourth | 9½ out |
| Monday, September 21 |
| » Lost to Mets (37-54), 4-3 | Shea Stadium (3-1) | 41-47 | Lost 3 |
| » W: Dan Boitano (2-1) L: Mark Lee (0-1) | Fourth | 10½ out |
| Tuesday, September 22 |
| » Defeated Mets (37-55), 5-3 | Shea Stadium (4-1) | 42-47 | |
| » W: Jim Bibby (6-3) L: Mike Scott (4-10) S: Rod Scurry (6) | Fourth | 9½ out |
| Wednesday, September 23 |
| » Lost to Expos (53-44), 3-2 | Stade Olympique (2-4) | 42-48 | |
| » W: Grant Jackson (2-2) L: Rick Rhoden (8-4) | Fourth | 9½ out |
| Thursday, September 24 |
| » Lost to Expos (54-44), 7-1 | Stade Olympique (2-5) | 42-49 | Lost 2 |
| » W: Bill Lee (4-5) L: Odell Jones (4-4) | Fourth | 9½ out |
| Friday, September 25 |
| » Defeated Cardinals (52-41), 5-4 | Busch Stadium II (2-2) | 43-49 | |
| » W: Eddie Solomon (8-5) L: Jim Kaat (6-6) S: Rod Scurry (7) | Fourth | 8½ out |
| Saturday, September 26 |
| » Lost to Cardinals (53-41), 5-3 | Busch Stadium II (2-3) | 43-50 | |
| » W: Bob Forsch (10-5) L: Mark Lee (0-2) S: Bruce Sutter (24) | Fourth | 9½ out |
| Sunday, September 27 |
| » Lost to Cardinals (54-41), 7-5 | Busch Stadium II (2-4) | 43-51 | Lost 2 |
| » W: Dave LaPoint (1-0) L: Pascual Perez (2-7) S: Bruce Sutter (25) | Fourth | 10½ out |
| Monday, September 28 |
| » Defeated Cubs (36-61), 4-0 | Three Rivers Stadium (20-23) | 44-51 | |
| » W: Rick Rhoden (9-4) L: Mike Griffin (2-5) | Fourth | 11 out |
| » Lost to Cubs (37-61), 3-1 | Three Rivers Stadium (20-24) | 44-52 | |
| » W: Dave Geisel (2-0) L: Bob Long (1-2) S: Randy Martz (5) | Fourth | 11 out |
| Tuesday, September 29 |
| » Defeated Cubs (37-62), 10-6 | Three Rivers Stadium (21-24) | 45-52 | |
| » W: Enrique Romo (1-3) L: Dick Tidrow (3-9) | Fourth | 11 out |
| Wednesday, September 30 |
| » Lost to Expos (57-47), 3-2 | Three Rivers Stadium (21-25) | 45-53 | |
| » W: Bill Gullickson (7-8) L: Eddie Solomon (8-6) S: Woodie Fryman (7) | Fourth | 11 out |
| Thursday, October 1 |
| » Lost to Expos (58-47), 5-2 | Three Rivers Stadium (21-26) | 45-54 | Lost 2 |
| » W: Ray Burris (9-7) L: Luis Tiant (2-5) S: Jeff Reardon (7) | Fourth | 12 out |
| Friday, October 2 |
| » Defeated Cardinals (57-43), 8-7 | Three Rivers Stadium (22-26) | 46-54 | |
| » W: Kent Tekulve (5-5) L: Bruce Sutter (3-5) | Fourth | 11 out |
| Saturday, October 3 |
| » Lost to Cardinals (58-43), 8-3 | Three Rivers Stadium (22-27) | 46-55 | |
| » W: John Martin (8-5) L: Ernie Camacho (0-1) | Fourth | 12 out |
| Sunday, October 4 |
| » Lost to Cardinals (59-43), 4-0 | Three Rivers Stadium (22-28) | 46-56 | Lost 2 |
| » W: Bob Shirley (6-4) L: Odell Jones (4-5) | Fourth | 13 out |
| Former Pirate Freddie Lindstrom dies in Chicago, IL at the age of 76. |
| Sunday, October 25 |
| Former Pirate Pete Reiser dies in Palm Springs, CA at the age of 63. |
| Friday, October 30 |
| Future Pirate Ian Snell is born in Dover, DE. |
| Tuesday, December 1 |
| Former Pirate Tony Piet dies in Hinsdale, IL at the age of 75. |
Game information provided by Retrosheet (www.retrosheet.org) |