| Wednesday, February 18 |
| Future Blue Jay Alexis Rios is born in Coffee, AL. |
| Thursday, April 9 |
| » Lost to Tigers (1-0), 6-2 | Tiger Stadium (0-1) | 0-1 | |
| » W: Jack Morris (1-0) L: Joey McLaughlin (0-1) | Third | 1 out |
| » Major-league debuts: George Bell (Blue Jays) |
| Friday, April 10 |
| » Major-league debuts: Chili Davis (Giants) |
| Saturday, April 11 |
| » Lost to Tigers (2-0), 6-2 | Tiger Stadium (0-2) | 0-2 | Lost 2 |
| » W: Milt Wilcox (1-0) L: Dave Stieb (0-1) | Fourth | 2 out |
| » Major-league debuts: Darrell Brown (Tigers) |
| Sunday, April 12 |
| » Defeated Tigers (2-1), 6-2 | Tiger Stadium (1-2) | 1-2 | |
| » W: Luis Leal (1-0) L: Howard Bailey (0-1) | Fourth | 1½ out |
| » Major-league debuts: Howard Bailey and Dave Rucker (Tigers) |
| Monday, April 13 |
| » Defeated Yankees (2-2), 5-1 | Exhibition Stadium (1-0) | 2-2 | Won 2 |
| » W: Jim Clancy (1-0) L: Tommy John (1-1) S: Roy Lee Jackson (1) | Third | 1 out |
| Wednesday, April 15 |
| » Lost to Yankees (3-2), 6-3 | Exhibition Stadium (1-1) | 2-3 | |
| » W: Rudy May (2-0) L: Jackson Todd (0-1) S: Rich Gossage (1) | Fourth | 2 out |
| Thursday, April 16 |
| » Lost to Tigers (5-1), 2-0 | Exhibition Stadium (1-2) | 2-4 | Lost 2 |
| » W: Milt Wilcox (2-0) L: Dave Stieb (0-2) S: Aurelio Lopez (1) | Fifth | 3 out |
| Friday, April 17 |
| » Lost to Tigers (6-1), 8-5 | Exhibition Stadium (1-3) | 2-5 | Lost 3 |
| » W: Howard Bailey (1-1) L: Luis Leal (1-1) S: Kevin Saucier (1) | Fifth | 4 out |
| Saturday, April 18 |
| » Lost to Tigers (7-1), 4-3 | Exhibition Stadium (1-4) | 2-6 | Lost 4 |
| » W: Dan Schatzeder (1-0) L: Jim Clancy (1-1) S: Aurelio Lopez (2) | Sixth | 5 out |
| Sunday, April 19 |
| » Defeated Tigers (7-2), 9-1 | Exhibition Stadium (2-4) | 3-6 | |
| » W: Mark Bomback (1-0) L: Jack Morris (1-1) | Sixth | 4 out |
| Monday, April 20 |
| » Lost to Brewers (3-4), 5-4 | Exhibition Stadium (2-5) | 3-7 | |
| » W: Randy Lerch (1-0) L: Mike Willis (0-1) | Seventh | 4 out |
| Tuesday, April 21 |
| » Lost to Brewers (4-4), 6-2 | Exhibition Stadium (2-6) | 3-8 | Lost 2 |
| » W: Moose Haas (1-0) L: Dave Stieb (0-3) | Seventh | 4 out |
| Wednesday, April 22 |
| » Lost to Brewers (5-4), 8-1 | Exhibition Stadium (2-7) | 3-9 | Lost 3 |
| » W: Mike Caldwell (2-1) L: Luis Leal (1-2) | Seventh | 4½ out |
| Friday, April 24 |
| » Lost to Yankees (8-4), 4-2 | Yankee Stadium (0-1) | 3-10 | Lost 4 |
| » W: Tommy John (2-1) L: Mark Bomback (1-1) S: Rich Gossage (4) | Sixth | 5½ out |
| Saturday, April 25 |
| » Defeated Yankees (8-5), 7-2 | Yankee Stadium (1-1) | 4-10 | |
| » W: Jackson Todd (1-1) L: Rudy May (3-1) | Sixth | 4½ out |
| Sunday, April 26 |
| » Defeated Yankees (8-6), 2-1 | Yankee Stadium (2-1) | 5-10 | Won 2 |
| » W: Dave Stieb (1-3) L: Tom Underwood (0-2) | Sixth | 4 out |
| Monday, April 27 |
| » Lost to Brewers (8-5), 4-3 | County Stadium (0-1) | 5-11 | |
| » W: Reggie Cleveland (1-0) L: Jerry Garvin (0-1) | Seventh | 4½ out |
| Tuesday, April 28 |
| » Defeated Brewers (8-6), 6-2 | County Stadium (1-1) | 6-11 | |
| » W: Mark Bomback (2-1) L: Mike Caldwell (2-2) | Seventh | 4 out |
| Wednesday, April 29 |
| » Defeated Brewers (8-7), 5-0 | County Stadium (2-1) | 7-11 | Won 2 |
| » W: Luis Leal (2-2) L: Jamie Easterly (0-1) | Sixth | 4½ out |
| Thursday, April 30 |
| » Lost to Orioles (7-8), 4-0 | Memorial Stadium (0-1) | 7-12 | |
| » W: Mike Flanagan (2-2) L: Jackson Todd (1-2) | Seventh | 4½ out |
| Saturday, May 2 |
| » Lost to Orioles (8-8), 4-3 | Memorial Stadium (0-2) | 7-13 | Lost 2 |
| » W: Jim Palmer (1-0) L: Mike Willis (0-2) | Seventh | 6½ out |
| » Lost to Orioles (9-8), 8-3 | Memorial Stadium (0-3) | 7-14 | Lost 3 |
| » W: Scott McGregor (2-1) L: Luis Leal (2-3) | Seventh | 6½ out |
| Sunday, May 3 |
| » Defeated Orioles (9-9), 4-2 | Memorial Stadium (1-3) | 8-14 | |
| » W: Mark Bomback (3-1) L: Steve Stone (1-3) S: Joey McLaughlin (1) | Seventh | 5½ out |
| Wednesday, May 6 |
| » Lost to Indians (11-5), 4-1 | Exhibition Stadium (2-8) | 8-15 | |
| » W: Bert Blyleven (3-1) L: Jackson Todd (1-3) | Seventh | 6½ out |
| Thursday, May 7 |
| » Defeated Indians (11-6), 6-2 | Exhibition Stadium (3-8) | 9-15 | |
| » W: Dave Stieb (2-3) L: Rick Waits (3-1) | Seventh | 5½ out |
| Friday, May 8 |
| » Lost to Red Sox (10-13), 4-2 | Exhibition Stadium (3-9) | 9-16 | |
| » W: Mike Torrez (2-2) L: Mark Bomback (3-2) S: Tom Burgmeier (4) | Seventh | 5½ out |
| Saturday, May 9 |
| » Lost to Red Sox (11-13), 10-3 | Exhibition Stadium (3-10) | 9-17 | Lost 2 |
| » W: Bob Stanley (3-1) L: Jim Clancy (1-2) | Seventh | 6½ out |
| Sunday, May 10 |
| » Lost to Red Sox (12-13), 9-5 | Exhibition Stadium (3-11) | 9-18 | Lost 3 |
| » W: Tom Burgmeier (2-0) L: Roy Lee Jackson (0-1) | Seventh | 7½ out |
| Monday, May 11 |
| » Lost to Red Sox (13-13), 7-6 | Exhibition Stadium (3-12) | 9-19 | Lost 4 |
| » W: Mark Clear (2-0) L: Mike Willis (0-3) | Seventh | 8½ out |
| Tuesday, May 12 |
| » Defeated Orioles (14-11), 5-2 | Exhibition Stadium (4-12) | 10-19 | |
| » W: Dave Stieb (3-3) L: Jim Palmer (1-1) | Seventh | 7½ out |
| Wednesday, May 13 |
| » Lost to Orioles (15-11), 4-0 | Exhibition Stadium (4-13) | 10-20 | |
| » W: Scott McGregor (3-1) L: Mark Bomback (3-3) | Sixth | 8½ out |
| Thursday, May 14 |
| » Lost to Orioles (16-11), 10-0 | Exhibition Stadium (4-14) | 10-21 | Lost 2 |
| » W: Mike Flanagan (4-3) L: Jim Clancy (1-3) | Seventh | 9 out |
| Friday, May 15 |
| » Lost to Indians (16-8), 3-0 | Cleveland Stadium (0-1) | 10-22 | Lost 3 |
| » W: Len Barker (3-1) L: Luis Leal (2-4) | Seventh | 10 out |
| Saturday, May 16 |
| » Defeated Indians (16-9), 4-1 | Cleveland Stadium (1-1) | 11-22 | |
| » W: Jackson Todd (2-3) L: Wayne Garland (2-3) | Sixth | 9 out |
| Sunday, May 17 |
| » Lost to Indians (17-9), 1-0 | Cleveland Stadium (1-2) | 11-23 | |
| » W: Rick Waits (4-2) L: Dave Stieb (3-4) S: Sid Monge (1) | Seventh | 11 out |
| » Lost to Indians (18-9), 2-1 | Cleveland Stadium (1-3) | 11-24 | Lost 2 |
| » W: Bert Blyleven (5-1) L: Roy Lee Jackson (0-2) | Seventh | 11 out |
| Monday, May 18 |
| » Lost to White Sox (18-14), 7-2 | Exhibition Stadium (4-15) | 11-25 | Lost 3 |
| » W: Steve Trout (3-1) L: Mark Bomback (3-4) | Seventh | 11½ out |
| Tuesday, May 19 |
| » Defeated White Sox (18-15), 9-5 | Exhibition Stadium (5-15) | 12-25 | |
| » W: Jim Clancy (2-3) L: La Marr Hoyt (3-1) S: Luis Leal (1) | Seventh | 11½ out |
| Wednesday, May 20 |
| » Lost to White Sox (19-15), 6-5 | Exhibition Stadium (5-16) | 12-26 | |
| » W: Ed Farmer (1-2) L: Joey McLaughlin (0-2) S: La Marr Hoyt (5) | Seventh | 12½ out |
| Friday, May 22 |
| » Lost to Athletics (26-16), 6-2 | Oakland-Alameda County Stadium (0-1) | 12-27 | Lost 2 |
| » W: Rick Langford (5-4) L: Dave Stieb (3-5) | Seventh | 13 out |
| Saturday, May 23 |
| » Lost to Athletics (27-16), 3-2 | Oakland-Alameda County Stadium (0-2) | 12-28 | Lost 3 |
| » W: Jeff Jones (3-1) L: Luis Leal (2-5) | Seventh | 14 out |
| Sunday, May 24 |
| » Lost to Athletics (28-16), 6-5 | Oakland-Alameda County Stadium (0-3) | 12-29 | Lost 4 |
| » W: Bob Owchinko (2-1) L: Joey McLaughlin (0-3) | Seventh | 14 out |
| » Lost to Athletics (29-16), 5-0 | Oakland-Alameda County Stadium (0-4) | 12-30 | Lost 5 |
| » W: Mike Norris (7-2) L: Jerry Garvin (0-2) | Seventh | 14 out |
| Monday, May 25 |
| » Lost to Angels (22-23), 2-1 | Anaheim Stadium (0-1) | 12-31 | Lost 6 |
| » W: Mike Witt (3-4) L: Jackson Todd (2-4) S: Andy Hassler (3) | Seventh | 15 out |
| Tuesday, May 26 |
| » Defeated Angels (22-24), 8-4 | Anaheim Stadium (1-1) | 13-31 | |
| » W: Roy Lee Jackson (1-2) L: Doug Rau (1-2) S: Joey McLaughlin (2) | Sixth | 15 out |
| Wednesday, May 27 |
| » Defeated Angels (22-25), 3-1 | Anaheim Stadium (2-1) | 14-31 | Won 2 |
| » W: Dave Stieb (4-5) L: Ken Forsch (6-3) | Seventh | 15 out |
| Friday, May 29 |
| » Defeated Athletics (30-19), 6-3 | Exhibition Stadium (6-16) | 15-31 | Won 3 |
| » W: Jim Clancy (3-3) L: Matt Keough (6-2) S: Roy Lee Jackson (2) | Seventh | 15 out |
| Saturday, May 30 |
| » Defeated Athletics (30-20), 6-5 | Exhibition Stadium (7-16) | 16-31 | Won 4 |
| » W: Luis Leal (3-5) L: Mike Norris (7-3) S: Joey McLaughlin (3) | Seventh | 14 out |
| Sunday, May 31 |
| » Lost to Athletics (31-20), 6-5 | Exhibition Stadium (7-17) | 16-32 | |
| » W: Bob Owchinko (3-1) L: Joey McLaughlin (0-4) | Seventh | 14 out |
| Monday, June 1 |
| » Lost to Angels (24-27), 3-0 | Exhibition Stadium (7-18) | 16-33 | Lost 2 |
| » W: Ken Forsch (7-3) L: Dave Stieb (4-6) | Seventh | 14½ out |
| Tuesday, June 2 |
| » Lost to Angels (25-27), 3-0 | Exhibition Stadium (7-19) | 16-34 | Lost 3 |
| » W: Dave Frost (1-0) L: Luis Leal (3-6) S: Andy Hassler (4) | Seventh | 14½ out |
| Wednesday, June 3 |
| » Lost to Angels (26-27), 17-6 | Exhibition Stadium (7-20) | 16-35 | Lost 4 |
| » W: Geoff Zahn (6-6) L: Jim Clancy (3-4) | Seventh | 14½ out |
| Friday, June 5 |
| » Lost to Rangers (29-20), 5-4 | Arlington Stadium (0-1) | 16-36 | Lost 5 |
| » W: Steve Comer (4-1) L: Luis Leal (3-7) | Seventh | 15 out |
| Saturday, June 6 |
| » Lost to Rangers (30-20), 4-1 | Arlington Stadium (0-2) | 16-37 | Lost 6 |
| » W: Fergie Jenkins (4-4) L: Dave Stieb (4-7) | Seventh | 16 out |
| Sunday, June 7 |
| » Lost to Rangers (31-20), 9-0 | Arlington Stadium (0-3) | 16-38 | Lost 7 |
| » W: Danny Darwin (7-4) L: Jackson Todd (2-5) | Seventh | 17 out |
| Monday, June 8 |
| » Lost to White Sox (28-22), 6-2 | Comiskey Park I (0-1) | 16-39 | Lost 8 |
| » W: Dennis Lamp (2-1) L: Jim Clancy (3-5) S: Kevin Hickey (1) | Seventh | 18 out |
| Tuesday, June 9 |
| » Lost to White Sox (29-22), 3-0 | Comiskey Park I (0-2) | 16-40 | Lost 9 |
| » W: Richard Dotson (7-3) L: Luis Leal (3-8) | Seventh | 19 out |
| Wednesday, June 10 |
| » Lost to Royals (19-30), 7-4 | Exhibition Stadium (7-21) | 16-41 | Lost 10 |
| » W: Dennis Leonard (6-7) L: Mark Bomback (3-5) | Sixth | 19 out |
| Thursday, June 11 |
| » Lost to Royals (20-30), 10-5 | Exhibition Stadium (7-22) | 16-42 | Lost 11 |
| » W: Renie Martin (2-3) L: Mike Willis (0-4) S: Dan Quisenberry (9) | Seventh | 19 out |
| Monday, August 10 |
| » Lost to Tigers (32-26), 4-3 | Tiger Stadium (1-3) | 16-43 | Lost 12 |
| » W: Kevin Saucier (1-0) L: Joey McLaughlin (0-5) | Seventh | 20 out |
| Tuesday, August 11 |
| » Defeated Tigers (32-27), 6-4 | Tiger Stadium (2-3) | 17-43 | |
| » W: Juan Berenguer (1-4) L: Dan Schatzeder (3-5) S: Roy Lee Jackson (3) | Seventh | 19 out |
| Wednesday, August 12 |
| » Defeated Tigers (32-28), 4-3 | Tiger Stadium (3-3) | 18-43 | Won 2 |
| » W: Dave Stieb (5-7) L: Jack Morris (9-4) S: Roy Lee Jackson (4) | Seventh | 19 out |
| Friday, August 14 |
| » Defeated Brewers (35-27), 5-4 | Exhibition Stadium (8-22) | 19-43 | Won 3 |
| » W: Jerry Garvin (1-2) L: Jamie Easterly (2-2) S: Roy Lee Jackson (5) | Seventh | 18½ out |
| Saturday, August 15 |
| » Defeated Brewers (35-28), 4-3 | Exhibition Stadium (9-22) | 20-43 | Won 4 |
| » W: Mark Bomback (4-5) L: Reggie Cleveland (2-2) S: Joey McLaughlin (4) | Seventh | 17½ out |
| Sunday, August 16 |
| » Lost to Brewers (36-28), 6-2 | Exhibition Stadium (9-23) | 20-44 | |
| » W: Mike Caldwell (8-5) L: Dave Stieb (5-8) S: Rollie Fingers (14) | Seventh | 18 out |
| » Lost to Brewers (37-28), 2-0 | Exhibition Stadium (9-24) | 20-45 | Lost 2 |
| » W: Randy Lerch (4-6) L: Jackson Todd (2-6) S: Rollie Fingers (15) | Seventh | 18 out |
| Monday, August 17 |
| » Lost to Royals (25-34), 5-3 | Royals Stadium (0-1) | 20-46 | Lost 3 |
| » W: Rich Gale (5-5) L: Jim Clancy (3-6) S: Dan Quisenberry (11) | Seventh | 18 out |
| Tuesday, August 18 |
| » Defeated Royals (25-35), 5-3 | Royals Stadium (1-1) | 21-46 | |
| » W: Luis Leal (4-8) L: Mike Jones (1-1) S: Roy Lee Jackson (6) | Seventh | 18 out |
| Wednesday, August 19 |
| » Defeated Royals (25-36), 9-4 | Royals Stadium (2-1) | 22-46 | Won 2 |
| » W: Juan Berenguer (2-4) L: Dennis Leonard (7-8) | Seventh | 17 out |
| Thursday, August 20 |
| » Major-league debuts: Brett Butler (Braves) |
| Friday, August 21 |
| » Defeated White Sox (37-27), 5-4 | Exhibition Stadium (10-24) | 23-46 | Won 3 |
| » W: Dave Stieb (6-8) L: Ed Farmer (2-3) | Seventh | 16½ out |
| Saturday, August 22 |
| » Lost to White Sox (38-27), 8-0 | Exhibition Stadium (10-25) | 23-47 | |
| » W: Britt Burns (8-2) L: Jim Clancy (3-7) | Seventh | 17½ out |
| Sunday, August 23 |
| » Lost to White Sox (39-27), 13-2 | Exhibition Stadium (10-26) | 23-48 | Lost 2 |
| » W: Steve Trout (7-4) L: Luis Leal (4-9) | Seventh | 18½ out |
| » Major-league debuts: Fred Manrique (Blue Jays) |
| Monday, August 24 |
| » Lost to Rangers (39-29), 3-0 | Exhibition Stadium (10-27) | 23-49 | Lost 3 |
| » W: Doc Medich (7-3) L: Juan Berenguer (2-5) | Seventh | 18½ out |
| Tuesday, August 25 |
| » Lost to Rangers (40-29), 6-1 | Exhibition Stadium (10-28) | 23-50 | Lost 4 |
| » W: Fergie Jenkins (5-6) L: Dave Stieb (6-9) | Seventh | 19½ out |
| Thursday, August 27 |
| » Lost to Royals (29-39), 11-5 | Exhibition Stadium (10-29) | 23-51 | Lost 5 |
| » W: Renie Martin (3-5) L: Jim Clancy (3-8) | Seventh | 20 out |
| Friday, August 28 |
| » Defeated Royals (29-40), 4-3 | Exhibition Stadium (11-29) | 24-51 | |
| » W: Joey McLaughlin (1-5) L: Ken Brett (1-1) | Sixth | 19 out |
| Saturday, August 29 |
| » Lost to Royals (30-40), 2-0 | Exhibition Stadium (11-30) | 24-52 | |
| » W: Mike Jones (2-1) L: Juan Berenguer (2-6) S: Dan Quisenberry (13) | Sixth | 20 out |
| Monday, August 31 |
| » Defeated Rangers (42-32), 3-0 | Arlington Stadium (1-3) | 25-52 | |
| » W: Dave Stieb (7-9) L: Fergie Jenkins (5-7) | Sixth | 20 out |
| Tuesday, September 1 |
| » Defeated Rangers (42-33), 9-3 | Arlington Stadium (2-3) | 26-52 | Won 2 |
| » W: Jim Clancy (4-8) L: Danny Darwin (8-7) | Seventh | 20 out |
| » Major-league debuts: Wayne Tolleson and Len Whitehouse (Rangers) |
| Wednesday, September 2 |
| » Lost to Rangers (43-33), 4-1 | Arlington Stadium (2-4) | 26-53 | |
| » W: Rick Honeycutt (9-3) L: Luis Leal (4-10) | Seventh | 20 out |
| Thursday, September 3 |
| » Lost to White Sox (42-34), 4-3 | Comiskey Park I (0-3) | 26-54 | Lost 2 |
| » W: La Marr Hoyt (6-3) L: Juan Berenguer (2-7) | Seventh | 20½ out |
| » Major-league debuts: Jesse Barfield (Blue Jays) |
| Friday, September 4 |
| » Defeated White Sox (42-35), 6-2 | Comiskey Park I (1-3) | 27-54 | |
| » W: Dave Stieb (8-9) L: Dennis Lamp (5-3) | Seventh | 20 out |
| Saturday, September 5 |
| » Defeated White Sox (42-36), 3-1 | Comiskey Park I (2-3) | 28-54 | Won 2 |
| » W: Jim Clancy (5-8) L: Ross Baumgarten (5-8) S: Joey McLaughlin (5) | Seventh | 20 out |
| Sunday, September 6 |
| » Defeated White Sox (42-37), 3-2 | Comiskey Park I (3-3) | 29-54 | Won 3 |
| » W: Luis Leal (5-10) L: Britt Burns (8-3) S: Roy Lee Jackson (7) | Seventh | 20 out |
| Monday, September 7 |
| » Lost to Twins (28-57), 4-0 | Metropolitan Stadium (0-1) | 29-55 | |
| » W: Darrell Jackson (3-2) L: Juan Berenguer (2-8) S: Doug Corbett (9) | Seventh | 21 out |
| Tuesday, September 8 |
| » Lost to Twins (29-57), 1-0 | Metropolitan Stadium (0-2) | 29-56 | Lost 2 |
| » W: Brad Havens (2-4) L: Dave Stieb (8-10) | Seventh | 21½ out |
| Wednesday, September 9 |
| » Lost to Twins (30-57), 3-1 | Metropolitan Stadium (0-3) | 29-57 | Lost 3 |
| » W: Fernando Arroyo (6-7) L: Jim Clancy (5-9) S: Doug Corbett (10) | Seventh | 22 out |
| Thursday, September 10 |
| » Defeated Mariners (33-55), 2-0 | Exhibition Stadium (12-30) | 30-57 | |
| » W: Luis Leal (6-10) L: Ken Clay (0-6) S: Joey McLaughlin (6) | Seventh | 21½ out |
| Friday, September 11 |
| » Lost to Mariners (34-55), 8-1 | Exhibition Stadium (12-31) | 30-58 | |
| » W: Glenn Abbott (3-6) L: Juan Berenguer (2-9) | Seventh | 22½ out |
| Saturday, September 12 |
| » Defeated Mariners (34-56), 3-0 | Exhibition Stadium (13-31) | 31-58 | |
| » W: Dave Stieb (9-10) L: Jim Beattie (2-2) | Seventh | 21½ out |
| Monday, September 14 |
| » Lost to Twins (34-57), 6-3 | Exhibition Stadium (13-32) | 31-59 | |
| » W: Brad Havens (3-4) L: Jim Clancy (5-10) S: Doug Corbett (13) | Seventh | 23 out |
| Tuesday, September 15 |
| » Defeated Twins (34-58), 4-2 | Exhibition Stadium (14-32) | 32-59 | |
| » W: Luis Leal (7-10) L: Fernando Arroyo (6-8) S: Joey McLaughlin (7) | Seventh | 22 out |
| Wednesday, September 16 |
| » Lost to Twins (35-58), 5-2 | Exhibition Stadium (14-33) | 32-60 | |
| » W: Albert Williams (5-8) L: Juan Berenguer (2-10) | Seventh | 22 out |
| Friday, September 18 |
| » Defeated Angels (43-52), 5-1 | Exhibition Stadium (15-33) | 33-60 | |
| » W: Dale Murray (1-0) L: Mike Witt (5-9) | Seventh | 22 out |
| Saturday, September 19 |
| » Defeated Angels (43-53), 6-4 | Exhibition Stadium (16-33) | 34-60 | Won 2 |
| » W: Jim Clancy (6-10) L: Dave Frost (1-7) | Seventh | 21 out |
| Sunday, September 20 |
| » Defeated Angels (43-54), 6-3 | Exhibition Stadium (17-33) | 35-60 | Won 3 |
| » W: Mark Bomback (5-5) L: Geoff Zahn (9-11) S: Joey McLaughlin (8) | Sixth | 20 out |
| Tuesday, September 22 |
| » Lost to Athletics (57-41), 3-2 | Exhibition Stadium (17-34) | 35-61 | |
| » W: Dave Beard (1-1) L: Luis Leal (7-11) | Seventh | 21 out |
| » Lost to Athletics (58-41), 4-2 | Exhibition Stadium (17-35) | 35-62 | Lost 2 |
| » W: Steve McCatty (13-6) L: Juan Berenguer (2-11) | Seventh | 21 out |
| Wednesday, September 23 |
| » Lost to Athletics (59-41), 6-0 | Exhibition Stadium (17-36) | 35-63 | Lost 3 |
| » W: Rick Langford (11-9) L: Jim Clancy (6-11) | Seventh | 21 out |
| Friday, September 25 |
| » Lost to Angels (47-55), 11-5 | Anaheim Stadium (2-2) | 35-64 | Lost 4 |
| » W: Geoff Zahn (10-11) L: Luis Leal (7-12) | Fifth | 21 out |
| Saturday, September 26 |
| » Lost to Angels (48-55), 6-3 | Anaheim Stadium (2-3) | 35-65 | Lost 5 |
| » W: Steve Renko (8-4) L: Juan Berenguer (2-12) S: Andy Hassler (5) | Seventh | 22 out |
| Sunday, September 27 |
| » Defeated Angels (48-56), 4-3 | Anaheim Stadium (3-3) | 36-65 | |
| » W: Dave Stieb (10-10) L: Angel Moreno (1-2) S: Joey McLaughlin (9) | Sixth | 21½ out |
| Tuesday, September 29 |
| » Lost to Athletics (61-44), 5-1 | Oakland-Alameda County Stadium (0-5) | 36-66 | |
| » W: Tom Underwood (4-6) L: Jim Clancy (6-12) | Sixth | 21½ out |
| Wednesday, September 30 |
| » Lost to Athletics (62-44), 3-0 | Oakland-Alameda County Stadium (0-6) | 36-67 | Lost 2 |
| » W: Mike Norris (12-9) L: Luis Leal (7-13) | Seventh | 22½ out |
| Friday, October 2 |
| » Lost to Mariners (43-64), 8-3 | Kingdome (0-1) | 36-68 | Lost 3 |
| » W: Ken Clay (2-7) L: Juan Berenguer (2-13) | Seventh | 23½ out |
| Saturday, October 3 |
| » Defeated Mariners (43-65), 4-3 | Kingdome (1-1) | 37-68 | |
| » W: Dave Stieb (11-10) L: Glenn Abbott (4-9) S: Joey McLaughlin (10) | Seventh | 23½ out |
| Sunday, October 4 |
| » Lost to Mariners (44-65), 2-0 | Kingdome (1-2) | 37-69 | |
| » W: Floyd Bannister (9-9) L: Jackson Todd (2-7) S: Shane Rawley (8) | Seventh | 23½ out |
| Sunday, November 29 |
| Future Blue Jay Guillermo Quiroz is born in Maracaibo, Venezuela. |
Game information provided by Retrosheet (www.retrosheet.org) |