| Saturday, February 2 |
| Former White Sox Jack Rothrock dies in San Bernardino, CA at the age of 75. |
| Tuesday, March 25 |
| Future White Sox Neal Cotts is born in Belleville, IL. |
| Thursday, April 10 |
| » Lost to Orioles (1-0), 5-3 | Comiskey Park I (0-1) | 0-1 | |
| » W: Jim Palmer (1-0) L: Steve Trout (0-1) S: Tim Stoddard (1) | Third | 1 out |
| » Major-league debuts: Harold Baines (White Sox) |
| Friday, April 11 |
| » Defeated Orioles (1-1), 8-4 | Comiskey Park I (1-1) | 1-1 | |
| » W: Ken Kravec (1-0) L: Mike Flanagan (0-1) S: Ed Farmer (1) | Third | 1 out |
| Saturday, April 12 |
| » Defeated Orioles (1-2), 8-2 | Comiskey Park I (2-1) | 2-1 | Won 2 |
| » W: Richard Dotson (1-0) L: Steve Stone (0-1) | Second | ½ out |
| Sunday, April 13 |
| » Defeated Orioles (1-3), 5-2 | Comiskey Park I (3-1) | 3-1 | Won 3 |
| » W: Ross Baumgarten (1-0) L: Sammy Stewart (0-1) S: Ed Farmer (2) | First | -- |
| Tuesday, April 15 |
| » Defeated Yankees (2-3), 4-3 | Comiskey Park I (4-1) | 4-1 | Won 4 |
| » W: Rich Wortham (1-0) L: Jim Kaat (0-1) | First | -- |
| Wednesday, April 16 |
| » Lost to Yankees (3-3), 6-0 | Comiskey Park I (4-2) | 4-2 | |
| » W: Tommy John (1-0) L: Ken Kravec (1-1) | Second | ½ out |
| Thursday, April 17 |
| » Defeated Yankees (3-4), 8-6 | Comiskey Park I (5-2) | 5-2 | |
| » W: Britt Burns (1-0) L: Mike Griffin (0-1) S: Ed Farmer (3) | First | -- |
| Friday, April 18 |
| » Lost to Orioles (5-3), 5-2 | Memorial Stadium (0-1) | 5-3 | |
| » W: Dave Ford (1-0) L: Richard Dotson (1-1) | Third | 1 out |
| Saturday, April 19 |
| » Defeated Orioles (5-4), 5-4 | Memorial Stadium (1-1) | 6-3 | |
| » W: Ed Farmer (1-0) L: Tippy Martinez (0-1) | Second | 1 out |
| Sunday, April 20 |
| » Defeated Orioles (5-5), 9-6 | Memorial Stadium (2-1) | 7-3 | Won 2 |
| » W: Rich Wortham (2-0) L: Sammy Stewart (0-2) S: Ed Farmer (4) | Second | ½ out |
| Monday, April 21 |
| » Lost to Red Sox (6-4), 9-8 | Fenway Park (0-1) | 7-4 | |
| » W: Skip Lockwood (1-1) L: Randy Scarbery (0-1) S: Dick Drago (1) | Third | 1½ out |
| Tuesday, April 22 |
| » Defeated Red Sox (6-5), 2-0 | Fenway Park (1-1) | 8-4 | |
| » W: Britt Burns (2-0) L: Mike Torrez (0-2) S: Mike Proly (1) | Second | ½ out |
| Thursday, April 24 |
| » Defeated Red Sox (6-6), 9-3 | Fenway Park (2-1) | 9-4 | Won 2 |
| » W: Richard Dotson (2-1) L: Bob Stanley (1-1) S: Ed Farmer (5) | Second | ½ out |
| Friday, April 25 |
| » Defeated Yankees (7-7), 6-0 | Yankee Stadium (1-0) | 10-4 | Won 3 |
| » W: Steve Trout (1-1) L: Ed Figueroa (1-2) | First | -- |
| Saturday, April 26 |
| » Defeated Yankees (7-8), 8-7 | Yankee Stadium (2-0) | 11-4 | Won 4 |
| » W: Ed Farmer (2-0) L: Tom Underwood (1-2) S: Randy Scarbery (1) | First | -- |
| Sunday, April 27 |
| » Lost to Yankees (8-8), 1-0 | Yankee Stadium (2-1) | 11-5 | |
| » W: Tommy John (3-0) L: Britt Burns (2-1) | First | -- |
| Tuesday, April 29 |
| » Lost to Red Sox (8-8), 11-1 | Comiskey Park I (5-3) | 11-6 | Lost 2 |
| » W: Bob Stanley (2-1) L: Ross Baumgarten (1-1) | First | -- |
| Wednesday, April 30 |
| » Defeated Red Sox (8-9), 2-1 | Comiskey Park I (6-3) | 12-6 | |
| » W: Richard Dotson (3-1) L: Dennis Eckersley (1-3) S: Ed Farmer (6) | First | -- |
| Thursday, May 1 |
| » Lost to Red Sox (9-9), 4-3 | Comiskey Park I (6-4) | 12-7 | |
| » W: Bruce Hurst (2-0) L: Steve Trout (1-2) S: Tom Burgmeier (4) | First | -- |
| Friday, May 2 |
| » Lost to Brewers (8-8), 8-0 | Comiskey Park I (6-5) | 12-8 | Lost 2 |
| » W: Mike Caldwell (3-1) L: Ken Kravec (1-2) | Second | ½ out |
| Saturday, May 3 |
| » Lost to Brewers (9-8), 4-1 | Comiskey Park I (6-6) | 12-9 | Lost 3 |
| » W: Moose Haas (2-3) L: Britt Burns (2-2) S: Reggie Cleveland (1) | Second | 1½ out |
| Sunday, May 4 |
| » Lost to Brewers (10-8), 11-1 | Comiskey Park I (6-7) | 12-10 | Lost 4 |
| » W: Jim Slaton (1-1) L: Ross Baumgarten (1-2) | Second | 2 out |
| Monday, May 5 |
| » Defeated Brewers (10-9), 11-7 | Comiskey Park I (7-7) | 13-10 | |
| » W: Randy Scarbery (1-1) L: Dan Boitano (0-1) S: Ed Farmer (7) | Second | 2 out |
| Tuesday, May 6 |
| » Defeated Royals (11-11), 2-0 | Comiskey Park I (8-7) | 14-10 | Won 2 |
| » W: Rich Wortham (3-0) L: Larry Gura (3-2) S: Ed Farmer (8) | Second | 1 out |
| Wednesday, May 7 |
| » Lost to Royals (12-11), 12-5 | Comiskey Park I (8-8) | 14-11 | |
| » W: Gary Christenson (2-0) L: Ken Kravec (1-3) | Second | 1 out |
| Thursday, May 8 |
| » Defeated Royals (12-12), 8-2 | Comiskey Park I (9-8) | 15-11 | |
| » W: Britt Burns (3-2) L: Paul Splittorff (3-2) | Second | ½ out |
| Friday, May 9 |
| » Lost to Rangers (14-11), 2-1 | Arlington Stadium (0-1) | 15-12 | |
| » W: Jim Kern (2-3) L: Mike Proly (0-1) | Third | 1 out |
| Saturday, May 10 |
| » Defeated Rangers (14-12), 10-6 | Arlington Stadium (1-1) | 16-12 | |
| » W: Ed Farmer (3-0) L: Danny Darwin (2-1) | Second | 1 out |
| Sunday, May 11 |
| » Lost to Rangers (15-12), 5-1 | Arlington Stadium (1-2) | 16-13 | |
| » W: Doc Medich (3-0) L: Rich Wortham (3-1) | Third | 2 out |
| Tuesday, May 13 |
| » Defeated Brewers (13-13), 6-5 | County Stadium (1-0) | 17-13 | |
| » W: Britt Burns (4-2) L: Reggie Cleveland (2-2) S: Ed Farmer (9) | Second | 1 out |
| Wednesday, May 14 |
| » Lost to Brewers (14-13), 5-1 | County Stadium (1-1) | 17-14 | |
| » W: Moose Haas (4-3) L: Mike Proly (0-2) S: Bob McClure (3) | Third | 1 out |
| Thursday, May 15 |
| » Defeated Brewers (14-14), 6-4 | County Stadium (2-1) | 18-14 | |
| » W: Richard Dotson (4-1) L: Lary Sorensen (2-3) S: Randy Scarbery (2) | Third | ½ out |
| Friday, May 16 |
| » Lost to Mariners (17-17), 4-2 | Comiskey Park I (9-9) | 18-15 | |
| » W: Jim Beattie (2-3) L: Steve Trout (1-3) S: Shane Rawley (2) | Third | ½ out |
| Saturday, May 17 |
| » Defeated Mariners (17-18), 4-0 | Comiskey Park I (10-9) | 19-15 | |
| » W: Britt Burns (5-2) L: Rick Honeycutt (6-1) | Second | ½ out |
| Sunday, May 18 |
| » Defeated Mariners (17-19), 6-5 | Comiskey Park I (11-9) | 20-15 | Won 2 |
| » W: Francisco Barrios (1-0) L: Rob Dressler (0-3) S: Ed Farmer (10) | First | -- |
| Monday, May 19 |
| » Defeated Twins (15-21), 1-0 | Comiskey Park I (12-9) | 21-15 | Won 3 |
| » W: Ken Kravec (2-3) L: Jerry Koosman (3-4) S: Ed Farmer (11) | First | -- |
| Tuesday, May 20 |
| » Defeated Twins (15-22), 4-2 | Comiskey Park I (13-9) | 22-15 | Won 4 |
| » W: Richard Dotson (5-1) L: Darrell Jackson (1-2) S: Ed Farmer (12) | First | -- |
| Wednesday, May 21 |
| » Lost to Twins (16-22), 3-2 | Comiskey Park I (13-10) | 22-16 | |
| » W: Geoff Zahn (3-5) L: Steve Trout (1-4) | First | -- |
| Friday, May 23 |
| » Lost to Mariners (20-20), 8-0 | Kingdome (0-1) | 22-17 | Lost 2 |
| » W: Rick Honeycutt (7-1) L: Britt Burns (5-3) S: Shane Rawley (3) | Second | ½ out |
| Saturday, May 24 |
| » Lost to Mariners (21-20), 5-4 | Kingdome (0-2) | 22-18 | Lost 3 |
| » W: Glenn Abbott (4-2) L: Ken Kravec (2-4) S: Dave Roberts (1) | Second | 1½ out |
| Sunday, May 25 |
| » Lost to Mariners (22-20), 8-3 | Kingdome (0-3) | 22-19 | Lost 4 |
| » W: Floyd Bannister (3-4) L: Randy Scarbery (1-2) | Second | 2½ out |
| Monday, May 26 |
| » Defeated Twins (16-26), 6-3 | Metropolitan Stadium (1-0) | 23-19 | |
| » W: Steve Trout (2-4) L: Geoff Zahn (3-6) S: Ed Farmer (13) | Second | 1½ out |
| Tuesday, May 27 |
| » Defeated Twins (16-27), 2-0 | Metropolitan Stadium (2-0) | 24-19 | Won 2 |
| » W: Britt Burns (6-3) L: Darrell Jackson (1-3) S: Mike Proly (2) | Second | 1½ out |
| Wednesday, May 28 |
| » Lost to Twins (17-27), 6-4 | Metropolitan Stadium (2-1) | 24-20 | |
| » W: Mike Marshall (1-3) L: Mike Proly (0-3) | Second | 1½ out |
| Thursday, May 29 |
| » Lost to Twins (18-27), 5-2 | Metropolitan Stadium (2-2) | 24-21 | Lost 2 |
| » W: Jerry Koosman (4-5) L: Richard Dotson (5-2) | Second | 2 out |
| Friday, May 30 |
| » Lost to Royals (26-18), 9-2 | Royals Stadium (0-1) | 24-22 | Lost 3 |
| » W: Larry Gura (7-2) L: Rich Wortham (3-2) | Third | 3 out |
| Saturday, May 31 |
| » Lost to Royals (27-18), 6-4 | Royals Stadium (0-2) | 24-23 | Lost 4 |
| » W: Renie Martin (6-2) L: Steve Trout (2-5) S: Dan Quisenberry (8) | Third | 4 out |
| Sunday, June 1 |
| » Defeated Royals (27-19), 6-1 | Royals Stadium (1-2) | 25-23 | |
| » W: Britt Burns (7-3) L: Dennis Leonard (4-5) | Third | 3 out |
| Monday, June 2 |
| » Tied Rangers, 1-1 | Comiskey Park I (13-10) | 25-23 | |
| » Starters: Jon Matlack vs Ross Baumgarten | Second | 2½ out |
| Tuesday, June 3 |
| » Defeated Rangers (23-24), 5-4 | Comiskey Park I (14-10) | 26-23 | Won 2 |
| » W: Ed Farmer (4-0) L: Jim Kern (2-7) S: Rich Wortham (1) | Second | 2½ out |
| Wednesday, June 4 |
| » Lost to Rangers (24-24), 4-3 | Comiskey Park I (14-11) | 26-24 | |
| » W: Doc Medich (5-3) L: Francisco Barrios (1-1) S: Sparky Lyle (5) | Second | 3 out |
| » Defeated Rangers (24-25), 5-1 | Comiskey Park I (15-11) | 27-24 | |
| » W: Richard Dotson (6-2) L: Dave Rajsich (0-1) | Second | 3 out |
| Friday, June 6 |
| » Defeated Indians (24-25), 8-7 | Comiskey Park I (16-11) | 28-24 | Won 2 |
| » W: Ed Farmer (5-0) L: Sid Monge (0-4) | Second | 3½ out |
| Sunday, June 8 |
| » Lost to Indians (25-25), 7-2 | Comiskey Park I (16-12) | 28-25 | |
| » W: John Denny (6-4) L: Britt Burns (7-4) S: Mike Stanton (2) | Second | 5 out |
| Tuesday, June 10 |
| » Lost to Blue Jays (26-26), 1-0 | Comiskey Park I (16-13) | 28-26 | Lost 2 |
| » W: Jim Clancy (5-3) L: Ross Baumgarten (1-3) | Second | 6 out |
| Wednesday, June 11 |
| » Defeated Blue Jays (26-27), 7-4 | Comiskey Park I (17-13) | 29-26 | |
| » W: Ken Kravec (3-4) L: Paul Mirabella (4-6) S: Ed Farmer (14) | Second | 5½ out |
| Friday, June 13 |
| » Lost to Tigers (25-28), 8-4 | Tiger Stadium (0-1) | 29-27 | |
| » W: Jack Morris (6-6) L: Steve Trout (2-6) | Second | 6½ out |
| Saturday, June 14 |
| » Lost to Tigers (26-28), 3-0 | Tiger Stadium (0-2) | 29-28 | Lost 2 |
| » W: Dan Petry (4-3) L: Britt Burns (7-5) | Second | 6½ out |
| Former White Sox Johnny Hodapp dies in Cincinnati, OH at the age of 75. |
| Monday, June 16 |
| » Lost to Indians (30-27), 5-3 | Cleveland Stadium (0-1) | 29-29 | Lost 3 |
| » W: Wayne Garland (2-0) L: Ed Farmer (5-1) | Second | 7 out |
| Tuesday, June 17 |
| » Defeated Indians (30-28), 5-3 | Cleveland Stadium (1-1) | 30-29 | |
| » W: La Marr Hoyt (1-0) L: Victor Cruz (3-3) | Second | 7 out |
| Wednesday, June 18 |
| » Lost to Blue Jays (29-30), 5-4 | Exhibition Stadium (0-1) | 30-30 | |
| » W: Dave Stieb (6-4) L: Steve Trout (2-7) | Second | 8½ out |
| » Lost to Blue Jays (30-30), 3-1 | Exhibition Stadium (0-2) | 30-31 | Lost 2 |
| » W: Jack Kucek (1-0) L: Richard Dotson (6-3) S: Joey McLaughlin (4) | Second | 8½ out |
| Friday, June 20 |
| » Lost to Tigers (29-30), 5-3 | Comiskey Park I (17-14) | 30-32 | Lost 3 |
| » W: Aurelio Lopez (6-3) L: Ed Farmer (5-2) | Second | 8 out |
| Saturday, June 21 |
| » Lost to Tigers (30-30), 4-1 | Comiskey Park I (17-15) | 30-33 | Lost 4 |
| » W: Milt Wilcox (7-4) L: Ross Baumgarten (1-4) | Second | 8 out |
| Sunday, June 22 |
| » Lost to Tigers (31-30), 7-1 | Comiskey Park I (17-16) | 30-34 | Lost 5 |
| » W: Dave Rozema (3-4) L: Ken Kravec (3-5) | Third | 9½ out |
| » Lost to Tigers (32-30), 6-4 | Comiskey Park I (17-17) | 30-35 | Lost 6 |
| » W: Jack Morris (8-6) L: Rich Wortham (3-3) S: Aurelio Lopez (7) | Third | 9½ out |
| Tuesday, June 24 |
| » Defeated Angels (23-42), 2-1 | Anaheim Stadium (1-0) | 31-35 | |
| » W: Britt Burns (8-5) L: Don Aase (4-7) S: Ed Farmer (15) | Second | 8½ out |
| Wednesday, June 25 |
| » Defeated Angels (23-43), 5-2 | Anaheim Stadium (2-0) | 32-35 | Won 2 |
| » W: Richard Dotson (7-3) L: Dave Lemanczyk (2-8) S: Ed Farmer (16) | Second | 8½ out |
| Thursday, June 26 |
| » Defeated Angels (23-44), 5-2 | Anaheim Stadium (3-0) | 33-35 | Won 3 |
| » W: Steve Trout (3-7) L: Frank Tanana (3-8) S: Mike Proly (3) | Second | 8 out |
| Friday, June 27 |
| » Lost to Athletics (32-39), 3-1 | Oakland-Alameda County Stadium (0-1) | 33-36 | |
| » W: Mike Norris (9-5) L: Ross Baumgarten (1-5) | Second | 9 out |
| Saturday, June 28 |
| » Defeated Athletics (32-40), 3-0 | Oakland-Alameda County Stadium (1-1) | 34-36 | |
| » W: Rich Wortham (4-3) L: Matt Keough (8-8) S: Ed Farmer (17) | Second | 9 out |
| Sunday, June 29 |
| » Defeated Athletics (32-41), 3-0 | Oakland-Alameda County Stadium (2-1) | 35-36 | Won 2 |
| » W: Britt Burns (9-5) L: Brian Kingman (3-8) S: Mike Proly (4) | Second | 8 out |
| Monday, June 30 |
| » Lost to Angels (25-46), 10-6 | Comiskey Park I (17-18) | 35-37 | |
| » W: Mark Clear (6-5) L: Ed Farmer (5-3) | Second | 8 out |
| Tuesday, July 1 |
| » Lost to Angels (26-46), 5-2 | Comiskey Park I (17-19) | 35-38 | Lost 2 |
| » W: Ed Halicki (1-1) L: Steve Trout (3-8) S: Mark Clear (3) | Second | 8 out |
| Wednesday, July 2 |
| » Defeated Angels (26-47), 1-0 | Comiskey Park I (18-19) | 36-38 | |
| » W: Ross Baumgarten (2-5) L: Frank Tanana (3-9) | Second | 8 out |
| Thursday, July 3 |
| » Lost to Angels (27-47), 7-3 | Comiskey Park I (18-20) | 36-39 | |
| » W: Dave Lemanczyk (3-8) L: Rich Wortham (4-4) S: Mark Clear (4) | Second | 8 out |
| Friday, July 4 |
| » Lost to Athletics (35-43), 2-0 | Comiskey Park I (18-21) | 36-40 | Lost 2 |
| » W: Brian Kingman (4-8) L: Britt Burns (9-6) | Third | 9 out |
| Saturday, July 5 |
| » Lost to Athletics (36-43), 5-0 | Comiskey Park I (18-22) | 36-41 | Lost 3 |
| » W: Rick Langford (5-9) L: Richard Dotson (7-4) | Third | 10 out |
| » Major-league debuts: Randy Johnson (White Sox) |
| Sunday, July 6 |
| » Defeated Athletics (36-44), 2-0 | Comiskey Park I (19-22) | 37-41 | |
| » W: Steve Trout (4-8) L: Mike Norris (10-6) | Second | 8½ out |
| » Defeated Athletics (36-45), 5-4 | Comiskey Park I (20-22) | 38-41 | Won 2 |
| » W: Ed Farmer (6-3) L: Bob Lacey (1-1) | Second | 8½ out |
| Thursday, July 10 |
| » Lost to Orioles (43-36), 9-2 | Comiskey Park I (20-23) | 38-42 | |
| » W: Scott McGregor (9-4) L: Britt Burns (9-7) | Second | 9½ out |
| Friday, July 11 |
| » Defeated Orioles (43-37), 5-4 | Comiskey Park I (21-23) | 39-42 | |
| » W: Mike Proly (1-3) L: Jim Palmer (8-6) S: Ed Farmer (18) | Second | 9½ out |
| Saturday, July 12 |
| » Lost to Yankees (53-28), 8-0 | Comiskey Park I (21-24) | 39-43 | |
| » W: Tommy John (13-3) L: Ross Baumgarten (2-6) | Second | 9½ out |
| Sunday, July 13 |
| » Lost to Yankees (54-28), 3-1 | Comiskey Park I (21-25) | 39-44 | Lost 2 |
| » W: Rudy May (7-3) L: Steve Trout (4-9) | Second | 10½ out |
| Monday, July 14 |
| » Lost to Yankees (55-28), 7-6 | Comiskey Park I (21-26) | 39-45 | Lost 3 |
| » W: Ron Davis (4-3) L: Ed Farmer (6-4) S: Rich Gossage (14) | Third | 11½ out |
| Tuesday, July 15 |
| » Defeated Rangers (40-45), 2-1 | Arlington Stadium (2-2) | 40-45 | |
| » W: Britt Burns (10-7) L: Fergie Jenkins (7-8) | Second | 11½ out |
| Wednesday, July 16 |
| » Lost to Rangers (41-45), 11-3 | Arlington Stadium (2-3) | 40-46 | |
| » W: Jon Matlack (6-5) L: Richard Dotson (7-5) S: Sparky Lyle (8) | Third | 12½ out |
| Thursday, July 17 |
| » Lost to Rangers (42-45), 3-2 | Arlington Stadium (2-4) | 40-47 | Lost 2 |
| » W: Danny Darwin (7-1) L: Mike Proly (1-4) | Fourth | 12½ out |
| Friday, July 18 |
| » Lost to Brewers (49-39), 5-1 | County Stadium (2-2) | 40-48 | Lost 3 |
| » W: Moose Haas (10-8) L: Steve Trout (4-10) | Fourth | 13½ out |
| Saturday, July 19 |
| » Defeated Brewers (49-40), 10-7 | County Stadium (3-2) | 41-48 | |
| » W: La Marr Hoyt (2-0) L: Bob McClure (1-4) S: Ed Farmer (19) | Fourth | 12½ out |
| Sunday, July 20 |
| » Lost to Brewers (50-40), 7-6 | County Stadium (3-3) | 41-49 | |
| » W: Jerry Augustine (3-2) L: Mike Proly (1-5) S: Bob McClure (7) | Fifth | 13½ out |
| Monday, July 21 |
| » Lost to Royals (56-36), 2-1 | Royals Stadium (1-3) | 41-50 | Lost 2 |
| » W: Dennis Leonard (10-7) L: Britt Burns (10-8) S: Dan Quisenberry (20) | Fifth | 14½ out |
| Tuesday, July 22 |
| » Defeated Royals (56-37), 6-1 | Royals Stadium (2-3) | 42-50 | |
| » W: Steve Trout (5-10) L: Steve Busby (0-1) | Fifth | 13½ out |
| Wednesday, July 23 |
| » Lost to Royals (57-37), 9-2 | Royals Stadium (2-4) | 42-51 | |
| » W: Larry Gura (13-4) L: Ross Baumgarten (2-7) | Fifth | 14½ out |
| Thursday, July 24 |
| » Lost to Royals (58-37), 12-4 | Royals Stadium (2-5) | 42-52 | Lost 2 |
| » W: Paul Splittorff (8-7) L: Rich Wortham (4-5) | Fifth | 15½ out |
| Friday, July 25 |
| » Lost to Rangers (47-47), 6-4 | Comiskey Park I (21-27) | 42-53 | Lost 3 |
| » W: Jim Kern (3-11) L: Ed Farmer (6-5) | Fifth | 16½ out |
| Saturday, July 26 |
| » Defeated Rangers (47-48), 4-3 | Comiskey Park I (22-27) | 43-53 | |
| » W: La Marr Hoyt (3-0) L: Fergie Jenkins (8-9) | Fifth | 15½ out |
| » Tied Rangers, 1-1 | Comiskey Park I (22-27) | 43-53 | |
| » Starters: Gaylord Perry vs Britt Burns | Fifth | 15½ out |
| Sunday, July 27 |
| » Defeated Rangers (47-49), 3-2 | Comiskey Park I (23-27) | 44-53 | Won 2 |
| » W: Steve Trout (6-10) L: Doc Medich (8-5) S: Mike Proly (5) | Fifth | 16 out |
| » Lost to Rangers (48-49), 4-3 | Comiskey Park I (23-28) | 44-54 | |
| » W: Charlie Hough (2-3) L: Mike Proly (1-6) | Fifth | 16 out |
| Future White Sox Felix Diaz is born in Las Matas de Farfan, D.R. |
| Tuesday, July 29 |
| » Lost to Brewers (54-44), 7-1 | Comiskey Park I (23-29) | 44-55 | Lost 2 |
| » W: Moose Haas (11-9) L: Richard Dotson (7-6) | Fifth | 17 out |
| Wednesday, July 30 |
| » Defeated Brewers (54-45), 6-5 | Comiskey Park I (24-29) | 45-55 | |
| » W: La Marr Hoyt (4-0) L: Lary Sorensen (7-7) S: Mike Proly (6) | Fifth | 16 out |
| Friday, August 1 |
| » Lost to Royals (63-39), 4-3 | Comiskey Park I (24-30) | 45-56 | |
| » W: Larry Gura (15-4) L: Britt Burns (10-9) S: Dan Quisenberry (21) | Fifth | 17½ out |
| Saturday, August 2 |
| » Lost to Royals (64-39), 8-2 | Comiskey Park I (24-31) | 45-57 | Lost 2 |
| » W: Rich Gale (9-7) L: Steve Trout (6-11) S: Marty Pattin (3) | Fifth | 18½ out |
| Sunday, August 3 |
| » Defeated Royals (64-40), 5-3 | Comiskey Park I (25-31) | 46-57 | |
| » W: Richard Dotson (8-6) L: Paul Splittorff (8-8) | Fifth | 17½ out |
| Tuesday, August 5 |
| » Lost to Orioles (59-44), 8-2 | Memorial Stadium (2-2) | 46-58 | |
| » W: Steve Stone (17-4) L: La Marr Hoyt (4-1) | Fifth | 19 out |
| Wednesday, August 6 |
| » Lost to Orioles (60-44), 4-1 | Memorial Stadium (2-3) | 46-59 | Lost 2 |
| » W: Mike Flanagan (12-8) L: Britt Burns (10-10) S: Tim Stoddard (16) | Fifth | 20 out |
| Thursday, August 7 |
| » Lost to Orioles (61-44), 2-1 | Memorial Stadium (2-4) | 46-60 | Lost 3 |
| » W: Scott McGregor (13-5) L: Steve Trout (6-12) | Fifth | 20½ out |
| Friday, August 8 |
| » Lost to Red Sox (56-51), 4-1 | Fenway Park (2-2) | 46-61 | Lost 4 |
| » W: Bill Campbell (1-0) L: Richard Dotson (8-7) S: Bob Stanley (5) | Fifth | 22 out |
| Saturday, August 9 |
| » Defeated Red Sox (56-52), 5-4 | Fenway Park (3-2) | 47-61 | |
| » W: Mike Proly (2-6) L: Steve Renko (6-5) S: Ed Farmer (20) | Fourth | 21 out |
| Sunday, August 10 |
| » Lost to Red Sox (57-52), 4-3 | Fenway Park (3-3) | 47-62 | |
| » W: Dennis Eckersley (8-10) L: La Marr Hoyt (4-2) S: Bob Stanley (6) | Fifth | 22 out |
| Monday, August 11 |
| » Lost to Yankees (68-42), 3-1 | Yankee Stadium (2-2) | 47-63 | Lost 2 |
| » W: Rudy May (10-5) L: Britt Burns (10-11) | Fifth | 22 out |
| » Major-league debuts: Leo Sutherland (White Sox) |
| Tuesday, August 12 |
| » Lost to Yankees (69-42), 8-4 | Yankee Stadium (2-3) | 47-64 | Lost 3 |
| » W: Doug Bird (3-0) L: Ed Farmer (6-6) | Fifth | 23 out |
| Wednesday, August 13 |
| » Defeated Yankees (69-43), 4-1 | Yankee Stadium (3-3) | 48-64 | |
| » W: Richard Dotson (9-7) L: Ron Guidry (12-8) | Fifth | 23 out |
| Friday, August 15 |
| » Lost to Red Sox (60-54), 8-5 | Comiskey Park I (25-32) | 48-65 | |
| » W: Dennis Eckersley (9-10) L: Mike Proly (2-7) S: Bob Stanley (9) | Fifth | 24 out |
| Monday, August 18 |
| » Lost to Indians (59-56), 4-2 | Comiskey Park I (25-33) | 48-66 | Lost 2 |
| » W: Len Barker (14-8) L: Britt Burns (10-12) | Fifth | 25½ out |
| » Defeated Indians (59-57), 7-2 | Comiskey Park I (26-33) | 49-66 | |
| » W: Steve Trout (7-12) L: Wayne Garland (6-5) | Fifth | 25½ out |
| Tuesday, August 19 |
| » Lost to Indians (60-57), 8-5 | Comiskey Park I (26-34) | 49-67 | |
| » W: Ross Grimsley (6-6) L: Richard Dotson (9-8) S: Sid Monge (10) | Fifth | 26½ out |
| Wednesday, August 20 |
| » Lost to Indians (61-57), 3-0 | Comiskey Park I (26-35) | 49-68 | Lost 2 |
| » W: Dan Spillner (11-9) L: Ken Kravec (3-6) | Fifth | 27½ out |
| Thursday, August 21 |
| » Defeated Blue Jays (50-69), 5-3 | Comiskey Park I (27-35) | 50-68 | |
| » W: La Marr Hoyt (5-2) L: Jesse Jefferson (4-11) S: Ed Farmer (21) | Fifth | 26½ out |
| Friday, August 22 |
| » Defeated Blue Jays (50-70), 2-0 | Comiskey Park I (28-35) | 51-68 | Won 2 |
| » W: Britt Burns (11-12) L: Jim Clancy (11-10) S: Ed Farmer (22) | Fifth | 25½ out |
| Saturday, August 23 |
| » Defeated Blue Jays (50-71), 5-1 | Comiskey Park I (29-35) | 52-68 | Won 3 |
| » W: Richard Dotson (10-8) L: Jack Kucek (3-6) | Fifth | 25½ out |
| Sunday, August 24 |
| » Lost to Blue Jays (51-71), 7-3 | Comiskey Park I (29-36) | 52-69 | |
| » W: Dave Stieb (11-9) L: Ross Baumgarten (2-8) S: Mike Barlow (2) | Fifth | 26½ out |
| Monday, August 25 |
| » Major-league debuts: Gary Cooper (Braves) |
| Tuesday, August 26 |
| » Lost to Tigers (65-58), 5-4 | Comiskey Park I (29-37) | 52-70 | Lost 2 |
| » W: Aurelio Lopez (10-4) L: Rich Wortham (4-6) S: Pat Underwood (2) | Fifth | 28 out |
| Wednesday, August 27 |
| » Defeated Tigers (65-59), 3-2 | Comiskey Park I (30-37) | 53-70 | |
| » W: Mike Proly (3-7) L: Dave Rozema (6-8) | Fourth | 28 out |
| Friday, August 29 |
| » Lost to Indians (66-60), 6-5 | Cleveland Stadium (1-2) | 53-71 | |
| » W: Sid Monge (2-4) L: Ed Farmer (6-7) S: Victor Cruz (11) | Fifth | 28½ out |
| Saturday, August 30 |
| » Lost to Indians (67-60), 6-2 | Cleveland Stadium (1-3) | 53-72 | Lost 2 |
| » W: Dan Spillner (13-9) L: Ross Baumgarten (2-9) S: Victor Cruz (12) | Fifth | 28½ out |
| Sunday, August 31 |
| » Defeated Indians (67-61), 10-8 | Cleveland Stadium (2-3) | 54-72 | |
| » W: La Marr Hoyt (6-2) L: Victor Cruz (5-6) S: Ed Farmer (23) | Fourth | 28 out |
| » Defeated Indians (67-62), 8-7 | Cleveland Stadium (3-3) | 55-72 | Won 2 |
| » W: Steve Trout (8-12) L: Ross Grimsley (6-8) S: Ed Farmer (24) | Fourth | 28 out |
| Monday, September 1 |
| » Defeated Tigers (67-62), 11-3 | Tiger Stadium (1-2) | 56-72 | Won 3 |
| » W: Britt Burns (12-12) L: Jack Morris (13-12) | Fourth | 27 out |
| Tuesday, September 2 |
| » Lost to Tigers (68-62), 11-2 | Tiger Stadium (1-3) | 56-73 | |
| » W: Mark Fidrych (1-2) L: Mike Proly (3-8) | Fifth | 28 out |
| » Lost to Tigers (69-62), 6-1 | Tiger Stadium (1-4) | 56-74 | Lost 2 |
| » W: Milt Wilcox (13-9) L: Richard Dotson (10-9) | Fifth | 28 out |
| Wednesday, September 3 |
| » Lost to Tigers (70-62), 5-4 | Tiger Stadium (1-5) | 56-75 | Lost 3 |
| » W: Aurelio Lopez (11-5) L: Rich Wortham (4-7) | Fifth | 28 out |
| Thursday, September 4 |
| » Lost to Blue Jays (56-77), 3-2 | Exhibition Stadium (0-3) | 56-76 | Lost 4 |
| » W: Jackson Todd (3-1) L: Ed Farmer (6-8) | Fifth | 28 out |
| Friday, September 5 |
| » Defeated Blue Jays (56-78), 3-0 | Exhibition Stadium (1-3) | 57-76 | |
| » W: La Marr Hoyt (7-2) L: Jim Clancy (13-11) | Fourth | 28 out |
| Sunday, September 7 |
| » Lost to Blue Jays (57-78), 3-1 | Exhibition Stadium (1-4) | 57-77 | |
| » W: Joey McLaughlin (5-8) L: Steve Trout (8-13) S: Mike Barlow (3) | Fifth | 29 out |
| » Lost to Blue Jays (58-78), 7-6 | Exhibition Stadium (1-5) | 57-78 | Lost 2 |
| » W: Ken Schrom (1-0) L: Mike Proly (3-9) S: Mike Barlow (4) | Fifth | 29 out |
| Monday, September 8 |
| » Defeated Mariners (50-87), 3-2 | Comiskey Park I (31-37) | 58-78 | |
| » W: Ed Farmer (7-8) L: Dave Heaverlo (5-3) | Fifth | 28 out |
| Tuesday, September 9 |
| » Lost to Mariners (51-87), 4-1 | Comiskey Park I (31-38) | 58-79 | |
| » W: Rick Honeycutt (9-15) L: Ross Baumgarten (2-10) S: Byron McLaughlin (2) | Fifth | 28 out |
| Wednesday, September 10 |
| » Defeated Mariners (51-88), 4-3 | Comiskey Park I (32-38) | 59-79 | |
| » W: La Marr Hoyt (8-2) L: Manny Sarmiento (0-1) S: Ed Farmer (25) | Fifth | 27 out |
| Friday, September 12 |
| » Defeated Twins (61-80), 5-3 | Comiskey Park I (33-38) | 60-79 | Won 2 |
| » W: Britt Burns (13-12) L: Jerry Koosman (12-13) S: Ed Farmer (26) | Fifth | 26½ out |
| Saturday, September 13 |
| » Lost to Twins (62-80), 6-5 | Comiskey Park I (33-39) | 60-80 | |
| » W: Geoff Zahn (12-18) L: Steve Trout (8-14) S: Doug Corbett (18) | Fifth | 26½ out |
| Sunday, September 14 |
| » Lost to Twins (63-80), 3-2 | Comiskey Park I (33-40) | 60-81 | Lost 2 |
| » W: Fernando Arroyo (5-6) L: Ross Baumgarten (2-11) S: Doug Corbett (19) | Fifth | 27½ out |
| Monday, September 15 |
| » Lost to Mariners (52-91), 12-1 | Kingdome (0-4) | 60-82 | Lost 3 |
| » W: Rob Dressler (4-8) L: La Marr Hoyt (8-3) | Fifth | 28 out |
| Tuesday, September 16 |
| » Defeated Mariners (52-92), 2-1 | Kingdome (1-4) | 61-82 | |
| » W: Richard Dotson (11-9) L: Glenn Abbott (10-11) S: Ed Farmer (27) | Fifth | 27½ out |
| Wednesday, September 17 |
| » Lost to Mariners (53-92), 4-0 | Kingdome (1-5) | 61-83 | |
| » W: Floyd Bannister (9-11) L: Britt Burns (13-13) S: Mike Parrott (1) | Fifth | 28 out |
| Thursday, September 18 |
| » Defeated Mariners (53-93), 5-4 | Kingdome (2-5) | 62-83 | |
| » W: Mike Proly (4-9) L: Shane Rawley (7-7) S: Guy Hoffman (1) | Fifth | 28 out |
| Friday, September 19 |
| » Lost to Twins (66-82), 6-3 | Metropolitan Stadium (2-3) | 62-84 | |
| » W: Albert Williams (4-2) L: Ed Farmer (7-9) S: Doug Corbett (20) | Fifth | 29 out |
| Saturday, September 20 |
| » Major-league debuts: Scott Holman (Mets) |
| Sunday, September 21 |
| » Lost to Twins (67-82), 5-4 | Metropolitan Stadium (2-4) | 62-85 | Lost 2 |
| » W: John Verhoeven (3-4) L: Dewey Robinson (0-1) | Fifth | 29 out |
| » Lost to Twins (68-82), 6-4 | Metropolitan Stadium (2-5) | 62-86 | Lost 3 |
| » W: |