| Thursday, April 10 |
| » Defeated Athletics (0-1), 9-7 | Oakland-Alameda County Stadium (1-0) | 1-0 | |
| » W: Doug Corbett (1-0) L: Steve McCatty (0-1) | First | -- |
| » Major-league debuts: Mike Davis (Athletics) Sal Butera and Doug Corbett (Twins) |
| Friday, April 11 |
| » Lost to Athletics (1-1), 1-0 | Oakland-Alameda County Stadium (1-1) | 1-1 | |
| » W: Matt Keough (1-0) L: Pete Redfern (0-1) | Third | 1 out |
| Saturday, April 12 |
| » Defeated Athletics (1-2), 6-0 | Oakland-Alameda County Stadium (2-1) | 2-1 | |
| » W: Geoff Zahn (1-0) L: Brian Kingman (0-1) | Second | ½ out |
| Sunday, April 13 |
| » Lost to Athletics (2-2), 4-1 | Oakland-Alameda County Stadium (2-2) | 2-2 | |
| » W: Mike Norris (1-0) L: Roger Erickson (0-1) | Third | 1 out |
| Monday, April 14 |
| » Defeated Angels (2-2), 5-3 | Anaheim Stadium (1-0) | 3-2 | |
| » W: Doug Corbett (2-0) L: Mark Clear (0-1) | Third | 1 out |
| Tuesday, April 15 |
| » Lost to Angels (3-2), 3-1 | Anaheim Stadium (1-1) | 3-3 | |
| » W: Frank Tanana (1-0) L: Jerry Koosman (0-1) | Fourth | 1½ out |
| Wednesday, April 16 |
| » Lost to Angels (4-2), 2-1 | Anaheim Stadium (1-2) | 3-4 | Lost 2 |
| » W: Dave Frost (2-0) L: Mike Marshall (0-1) | Fifth | 2 out |
| Thursday, April 17 |
| » Lost to Mariners (5-3), 4-3 | Kingdome (0-1) | 3-5 | Lost 3 |
| » W: Rick Honeycutt (2-0) L: Geoff Zahn (1-1) | Sixth | 2½ out |
| Friday, April 18 |
| » Lost to Mariners (6-3), 3-1 | Kingdome (0-2) | 3-6 | Lost 4 |
| » W: Floyd Bannister (2-0) L: Roger Erickson (0-2) | Sixth | 4 out |
| » Lost to Mariners (7-3), 3-2 | Kingdome (0-3) | 3-7 | Lost 5 |
| » W: Byron McLaughlin (1-0) L: Terry Felton (0-1) S: Shane Rawley (1) | Sixth | 4 out |
| Saturday, April 19 |
| » Defeated Mariners (7-4), 8-3 | Kingdome (1-3) | 4-7 | |
| » W: Jerry Koosman (1-1) L: Glenn Abbott (1-1) | Sixth | 4 out |
| Sunday, April 20 |
| » Defeated Mariners (7-5), 4-3 | Kingdome (2-3) | 5-7 | Won 2 |
| » W: Pete Redfern (1-1) L: Mike Parrott (1-2) S: Mike Marshall (1) | Fifth | 3½ out |
| Tuesday, April 22 |
| » Defeated Angels (4-7), 8-1 | Metropolitan Stadium (1-0) | 6-7 | Won 3 |
| » W: Geoff Zahn (2-1) L: Dave Frost (2-1) | Fifth | 3 out |
| Wednesday, April 23 |
| » Lost to Angels (5-7), 17-0 | Metropolitan Stadium (1-1) | 6-8 | |
| » W: Bruce Kison (1-2) L: Terry Felton (0-2) | Sixth | 4 out |
| Friday, April 25 |
| » Defeated Athletics (10-5), 10-3 | Metropolitan Stadium (2-1) | 7-8 | |
| » W: Jerry Koosman (2-1) L: Matt Keough (3-1) | Sixth | 3½ out |
| Saturday, April 26 |
| » Defeated Athletics (10-6), 5-1 | Metropolitan Stadium (3-1) | 8-8 | Won 2 |
| » W: Pete Redfern (2-1) L: Steve McCatty (2-3) | Sixth | 3½ out |
| Sunday, April 27 |
| » Defeated Athletics (10-7), 20-11 | Metropolitan Stadium (4-1) | 9-8 | Won 3 |
| » W: Doug Corbett (3-0) L: Brian Kingman (1-3) | Fourth | 2½ out |
| Monday, April 28 |
| » Lost to Mariners (10-9), 6-4 | Metropolitan Stadium (4-2) | 9-9 | |
| » W: Rick Honeycutt (4-0) L: Terry Felton (0-3) S: Dave Heaverlo (2) | Fifth | 3 out |
| Tuesday, April 29 |
| » Lost to Mariners (11-9), 5-3 | Metropolitan Stadium (4-3) | 9-10 | Lost 2 |
| » W: Shane Rawley (1-1) L: Mike Marshall (0-2) | Sixth | 3 out |
| Wednesday, April 30 |
| » Defeated Mariners (11-10), 10-3 | Metropolitan Stadium (5-3) | 10-10 | |
| » W: Pete Redfern (3-1) L: Mike Parrott (1-4) | Fifth | 3 out |
| Friday, May 2 |
| » Lost to Yankees (10-9), 9-6 | Metropolitan Stadium (5-4) | 10-11 | |
| » W: Ron Guidry (1-0) L: Geoff Zahn (2-2) S: Rudy May (2) | Sixth | 3 out |
| Saturday, May 3 |
| » Lost to Yankees (11-9), 7-3 | Metropolitan Stadium (5-5) | 10-12 | Lost 2 |
| » W: Tommy John (4-0) L: Darrell Jackson (0-1) | Seventh | 4 out |
| Sunday, May 4 |
| » Lost to Yankees (12-9), 10-1 | Metropolitan Stadium (5-6) | 10-13 | Lost 3 |
| » W: Tom Underwood (2-3) L: Jerry Koosman (2-2) | Sixth | 4½ out |
| Monday, May 5 |
| » Defeated Orioles (9-13), 4-2 | Memorial Stadium (1-0) | 11-13 | |
| » W: Pete Redfern (4-1) L: Steve Stone (2-3) S: Doug Corbett (1) | Seventh | 4½ out |
| Tuesday, May 6 |
| » Lost to Orioles (10-13), 10-3 | Memorial Stadium (1-1) | 11-14 | |
| » W: Scott McGregor (1-1) L: Geoff Zahn (2-3) | Seventh | 4½ out |
| Wednesday, May 7 |
| » Lost to Orioles (11-13), 8-6 | Memorial Stadium (1-2) | 11-15 | Lost 2 |
| » W: Sammy Stewart (1-2) L: Mike Marshall (0-3) S: Tippy Martinez (1) | Seventh | 4½ out |
| » Major-league debuts: Al Williams (Twins) |
| Friday, May 9 |
| » Lost to Yankees (15-9), 5-2 | Yankee Stadium (0-1) | 11-16 | Lost 3 |
| » W: Ron Guidry (2-0) L: Jerry Koosman (2-3) S: Rich Gossage (3) | Seventh | 5 out |
| Saturday, May 10 |
| » Defeated Yankees (15-10), 1-0 | Yankee Stadium (1-1) | 12-16 | |
| » W: Darrell Jackson (1-1) L: Rudy May (1-1) S: Doug Corbett (2) | Fifth | 5 out |
| Sunday, May 11 |
| » Lost to Yankees (16-10), 5-0 | Yankee Stadium (1-2) | 12-17 | |
| » W: Tommy John (6-0) L: Geoff Zahn (2-4) | Sixth | 6 out |
| Monday, May 12 |
| » Defeated Red Sox (13-15), 4-3 | Fenway Park (1-0) | 13-17 | |
| » W: Pete Redfern (5-1) L: Mike Torrez (0-4) S: Doug Corbett (3) | Sixth | 5½ out |
| Tuesday, May 13 |
| » Lost to Red Sox (14-15), 10-5 | Fenway Park (1-1) | 13-18 | |
| » W: Steve Renko (2-0) L: John Verhoeven (0-1) S: Tom Burgmeier (5) | Fifth | 5½ out |
| Wednesday, May 14 |
| » Lost to Red Sox (15-15), 7-6 | Fenway Park (1-2) | 13-19 | Lost 2 |
| » W: Tom Burgmeier (2-0) L: Doug Corbett (3-1) | Seventh | 5½ out |
| Friday, May 16 |
| » Defeated Brewers (14-15), 4-3 | Metropolitan Stadium (6-6) | 14-19 | |
| » W: Jerry Koosman (3-3) L: Bob McClure (1-1) S: Doug Corbett (4) | Seventh | 4½ out |
| Saturday, May 17 |
| » Lost to Brewers (15-15), 14-11 | Metropolitan Stadium (6-7) | 14-20 | |
| » W: Jerry Augustine (1-2) L: Geoff Zahn (2-5) S: Bill Castro (1) | Sixth | 5½ out |
| Sunday, May 18 |
| » Defeated Brewers (15-16), 10-4 | Metropolitan Stadium (7-7) | 15-20 | |
| » W: Pete Redfern (6-1) L: Bill Travers (1-2) | Fifth | 5 out |
| Monday, May 19 |
| » Lost to White Sox (21-15), 1-0 | Comiskey Park I (0-1) | 15-21 | |
| » W: Ken Kravec (2-3) L: Jerry Koosman (3-4) S: Ed Farmer (11) | Seventh | 6 out |
| Tuesday, May 20 |
| » Lost to White Sox (22-15), 4-2 | Comiskey Park I (0-2) | 15-22 | Lost 2 |
| » W: Richard Dotson (5-1) L: Darrell Jackson (1-2) S: Ed Farmer (12) | Seventh | 7 out |
| Wednesday, May 21 |
| » Defeated White Sox (22-16), 3-2 | Comiskey Park I (1-2) | 16-22 | |
| » W: Geoff Zahn (3-5) L: Steve Trout (1-4) | Seventh | 6 out |
| Friday, May 23 |
| » Lost to Brewers (17-18), 5-0 | County Stadium (0-1) | 16-23 | |
| » W: Bill Travers (2-2) L: Pete Redfern (6-2) | Seventh | 6½ out |
| Saturday, May 24 |
| » Lost to Brewers (18-18), 4-0 | County Stadium (0-2) | 16-24 | Lost 2 |
| » W: Moose Haas (5-3) L: Jerry Koosman (3-5) | Seventh | 7½ out |
| Sunday, May 25 |
| » Lost to Brewers (19-18), 3-2 | County Stadium (0-3) | 16-25 | Lost 3 |
| » W: Lary Sorensen (4-3) L: Roger Erickson (0-3) | Seventh | 8½ out |
| Monday, May 26 |
| » Lost to White Sox (23-19), 6-3 | Metropolitan Stadium (7-8) | 16-26 | Lost 4 |
| » W: Steve Trout (2-4) L: Geoff Zahn (3-6) S: Ed Farmer (13) | Seventh | 8½ out |
| Tuesday, May 27 |
| » Lost to White Sox (24-19), 2-0 | Metropolitan Stadium (7-9) | 16-27 | Lost 5 |
| » W: Britt Burns (6-3) L: Darrell Jackson (1-3) S: Mike Proly (2) | Seventh | 9½ out |
| Wednesday, May 28 |
| » Defeated White Sox (24-20), 6-4 | Metropolitan Stadium (8-9) | 17-27 | |
| » W: Mike Marshall (1-3) L: Mike Proly (0-3) | Seventh | 8½ out |
| Thursday, May 29 |
| » Defeated White Sox (24-21), 5-2 | Metropolitan Stadium (9-9) | 18-27 | Won 2 |
| » W: Jerry Koosman (4-5) L: Richard Dotson (5-2) | Seventh | 8 out |
| Friday, May 30 |
| » Lost to Orioles (21-24), 3-2 | Metropolitan Stadium (9-10) | 18-28 | |
| » W: Mike Flanagan (5-3) L: Doug Corbett (3-2) S: Tippy Martinez (3) | Seventh | 9 out |
| Saturday, May 31 |
| » Lost to Orioles (22-24), 11-1 | Metropolitan Stadium (9-11) | 18-29 | Lost 2 |
| » W: Scott McGregor (4-2) L: Geoff Zahn (3-7) | Seventh | 10 out |
| Monday, June 2 |
| » Lost to Red Sox (23-24), 6-2 | Metropolitan Stadium (9-12) | 18-30 | Lost 3 |
| » W: Bob Stanley (4-5) L: Pete Redfern (6-3) | Sixth | 9½ out |
| Tuesday, June 3 |
| » Defeated Red Sox (23-25), 9-4 | Metropolitan Stadium (10-12) | 19-30 | |
| » W: Jerry Koosman (5-5) L: Jack Billingham (1-3) | Seventh | 9½ out |
| Friday, June 6 |
| » Defeated Blue Jays (24-24), 5-0 | Metropolitan Stadium (11-12) | 20-30 | Won 2 |
| » W: Geoff Zahn (4-7) L: Paul Mirabella (4-5) | Sixth | 10½ out |
| Saturday, June 7 |
| » Defeated Blue Jays (24-25), 3-2 | Metropolitan Stadium (12-12) | 21-30 | Won 3 |
| » W: Darrell Jackson (2-3) L: Dave Stieb (5-3) S: Doug Corbett (5) | Fifth | 10½ out |
| Sunday, June 8 |
| » Defeated Blue Jays (24-26), 5-1 | Metropolitan Stadium (13-12) | 22-30 | Won 4 |
| » W: Roger Erickson (1-3) L: Jesse Jefferson (2-3) S: Doug Corbett (6) | Sixth | 11 out |
| » Lost to Blue Jays (25-26), 6-4 | Metropolitan Stadium (13-13) | 22-31 | |
| » W: Joey McLaughlin (3-3) L: Fernando Arroyo (0-1) | Sixth | 11 out |
| Tuesday, June 10 |
| » Lost to Tigers (23-27), 8-3 | Tiger Stadium (0-1) | 22-32 | Lost 2 |
| » W: Milt Wilcox (5-4) L: Geoff Zahn (4-8) | Sixth | 12 out |
| Wednesday, June 11 |
| » Defeated Tigers (23-28), 9-5 | Tiger Stadium (1-1) | 23-32 | |
| » W: Darrell Jackson (3-3) L: Dave Rozema (2-3) S: Jerry Koosman (1) | Sixth | 11½ out |
| Thursday, June 12 |
| » Lost to Tigers (24-28), 8-4 | Tiger Stadium (1-2) | 23-33 | |
| » W: Pat Underwood (1-4) L: Geoff Zahn (4-9) S: Aurelio Lopez (6) | Sixth | 12 out |
| Friday, June 13 |
| » Lost to Indians (27-27), 6-2 | Cleveland Stadium (0-1) | 23-34 | Lost 2 |
| » W: John Denny (7-4) L: Jerry Koosman (5-6) | Sixth | 13 out |
| Saturday, June 14 |
| » Lost to Indians (28-27), 3-2 | Cleveland Stadium (0-2) | 23-35 | Lost 3 |
| » W: Len Barker (6-4) L: Roger Erickson (1-4) | Sixth | 13 out |
| Sunday, June 15 |
| » Lost to Indians (29-27), 14-5 | Cleveland Stadium (0-3) | 23-36 | Lost 4 |
| » W: Dan Spillner (7-3) L: Darrell Jackson (3-4) | Sixth | 14 out |
| Monday, June 16 |
| » Defeated Blue Jays (28-29), 4-0 | Exhibition Stadium (1-0) | 24-36 | |
| » W: Geoff Zahn (5-9) L: Jesse Jefferson (2-4) | Sixth | 13 out |
| Tuesday, June 17 |
| » Defeated Blue Jays (28-30), 8-6 | Exhibition Stadium (2-0) | 25-36 | Won 2 |
| » W: Doug Corbett (4-2) L: Paul Mirabella (4-7) | Sixth | 13 out |
| Thursday, June 19 |
| » Defeated Tigers (28-30), 5-1 | Metropolitan Stadium (14-13) | 26-36 | Won 3 |
| » W: Darrell Jackson (4-4) L: Dan Schatzeder (2-6) | Sixth | 12½ out |
| Friday, June 20 |
| » Lost to Indians (32-29), 4-3 | Metropolitan Stadium (14-14) | 26-37 | |
| » W: Victor Cruz (4-3) L: Pete Redfern (6-4) S: Mike Stanton (4) | Sixth | 12½ out |
| Saturday, June 21 |
| » Defeated Indians (32-30), 3-2 | Metropolitan Stadium (15-14) | 27-37 | |
| » W: Geoff Zahn (6-9) L: Wayne Garland (2-1) S: Darrell Jackson (1) | Sixth | 11½ out |
| Sunday, June 22 |
| » Lost to Indians (33-30), 11-6 | Metropolitan Stadium (15-15) | 27-38 | |
| » W: Rick Waits (5-6) L: Pete Redfern (6-5) | Sixth | 12½ out |
| Monday, June 23 |
| » Defeated Royals (40-27), 4-1 | Metropolitan Stadium (16-15) | 28-38 | |
| » W: Jerry Koosman (6-6) L: Larry Gura (9-3) | Sixth | 11½ out |
| Tuesday, June 24 |
| » Defeated Royals (40-28), 2-1 | Metropolitan Stadium (17-15) | 29-38 | Won 2 |
| » W: Darrell Jackson (5-4) L: Dan Quisenberry (4-4) | Sixth | 11½ out |
| » Lost to Royals (41-28), 4-2 | Metropolitan Stadium (17-16) | 29-39 | |
| » W: Renie Martin (8-4) L: Roger Erickson (1-5) S: Dan Quisenberry (12) | Sixth | 11½ out |
| Wednesday, June 25 |
| » Lost to Royals (42-28), 4-1 | Metropolitan Stadium (17-17) | 29-40 | Lost 2 |
| » W: Paul Splittorff (5-4) L: Geoff Zahn (6-10) S: Dan Quisenberry (13) | Sixth | 12½ out |
| Friday, June 27 |
| » Lost to Rangers (33-37), 5-0 | Arlington Stadium (0-1) | 29-41 | Lost 3 |
| » W: Gaylord Perry (4-6) L: Pete Redfern (6-6) | Sixth | 13½ out |
| Saturday, June 28 |
| » Lost to Rangers (34-37), 11-3 | Arlington Stadium (0-2) | 29-42 | Lost 4 |
| » W: Steve Comer (2-3) L: Jerry Koosman (6-7) S: Danny Darwin (1) | Sixth | 14½ out |
| Sunday, June 29 |
| » Defeated Rangers (34-38), 5-3 | Arlington Stadium (1-2) | 30-42 | |
| » W: Roger Erickson (2-5) L: Doc Medich (7-4) S: Doug Corbett (7) | Fifth | 13½ out |
| Monday, June 30 |
| » Defeated Royals (44-30), 12-3 | Royals Stadium (1-0) | 31-42 | Won 2 |
| » W: Darrell Jackson (6-4) L: Renie Martin (8-5) | Fifth | 12½ out |
| Tuesday, July 1 |
| » Defeated Royals (44-31), 2-1 | Royals Stadium (2-0) | 32-42 | Won 3 |
| » W: Doug Corbett (5-2) L: Paul Splittorff (5-5) | Fifth | 11½ out |
| Wednesday, July 2 |
| » Lost to Royals (45-31), 4-3 | Royals Stadium (2-1) | 32-43 | |
| » W: Dan Quisenberry (5-4) L: Jerry Koosman (6-8) | Fifth | 12½ out |
| Thursday, July 3 |
| » Defeated Rangers (36-40), 10-3 | Metropolitan Stadium (18-17) | 33-43 | |
| » W: Roger Erickson (3-5) L: Steve Comer (2-4) S: Doug Corbett (8) | Fifth | 11½ out |
| Friday, July 4 |
| » Lost to Rangers (37-40), 4-3 | Metropolitan Stadium (18-18) | 33-44 | |
| » W: Danny Darwin (5-1) L: John Verhoeven (0-2) | Sixth | 12½ out |
| Saturday, July 5 |
| » Defeated Rangers (37-41), 2-1 | Metropolitan Stadium (19-18) | 34-44 | |
| » W: Geoff Zahn (7-10) L: Fergie Jenkins (7-6) | Fifth | 12½ out |
| Sunday, July 6 |
| » Defeated Rangers (37-42), 4-1 | Metropolitan Stadium (20-18) | 35-44 | Won 2 |
| » W: Fernando Arroyo (1-1) L: Jon Matlack (4-5) S: Jerry Koosman (2) | Fifth | 11½ out |
| Thursday, July 10 |
| » Defeated Mariners (35-46), 12-4 | Kingdome (3-3) | 36-44 | Won 3 |
| » W: Jerry Koosman (7-8) L: Rick Honeycutt (7-7) | Fourth | 11½ out |
| Friday, July 11 |
| » Defeated Mariners (35-47), 6-3 | Kingdome (4-3) | 37-44 | Won 4 |
| » W: Darrell Jackson (7-4) L: Glenn Abbott (7-4) S: Doug Corbett (9) | Fourth | 11½ out |
| Saturday, July 12 |
| » Defeated Mariners (35-48), 8-3 | Metropolitan Stadium (21-18) | 38-44 | Won 5 |
| » W: Geoff Zahn (8-10) L: Floyd Bannister (6-7) | Third | 10½ out |
| Sunday, July 13 |
| » Defeated Mariners (35-49), 7-6 | Metropolitan Stadium (22-18) | 39-44 | Won 6 |
| » W: Doug Corbett (6-2) L: Shane Rawley (4-3) | Second | 10½ out |
| Monday, July 14 |
| » Lost to Mariners (36-49), 8-5 | Metropolitan Stadium (22-19) | 39-45 | |
| » W: Rick Honeycutt (8-7) L: Fernando Arroyo (1-2) S: Dave Roberts (2) | Third | 11½ out |
| Tuesday, July 15 |
| » Defeated Yankees (55-29), 5-4 | Yankee Stadium (2-2) | 40-45 | |
| » W: Jerry Koosman (8-8) L: Ron Guidry (10-5) S: Doug Corbett (10) | Second | 11½ out |
| Wednesday, July 16 |
| » Lost to Yankees (56-29), 11-1 | Yankee Stadium (2-3) | 40-46 | |
| » W: Tom Underwood (8-6) L: Darrell Jackson (7-5) | Third | 12½ out |
| Thursday, July 17 |
| » Lost to Yankees (57-29), 10-3 | Yankee Stadium (2-4) | 40-47 | Lost 2 |
| » W: Tommy John (14-3) L: Geoff Zahn (8-11) | Fourth | 12½ out |
| Friday, July 18 |
| » Lost to Red Sox (46-41), 1-0 | Fenway Park (1-3) | 40-48 | Lost 3 |
| » W: Mike Torrez (5-10) L: Roger Erickson (3-6) | Fourth | 13½ out |
| Saturday, July 19 |
| » Defeated Red Sox (46-42), 4-0 | Fenway Park (2-3) | 41-48 | |
| » W: Fernando Arroyo (2-2) L: Bob Ojeda (0-1) | Fourth | 12½ out |
| Sunday, July 20 |
| » Defeated Red Sox (46-43), 5-4 | Fenway Park (3-3) | 42-48 | Won 2 |
| » W: Doug Corbett (7-2) L: Dick Drago (3-4) | Fourth | 12½ out |
| Monday, July 21 |
| » Defeated Orioles (48-42), 8-7 | Metropolitan Stadium (23-19) | 43-48 | Won 3 |
| » W: John Verhoeven (1-2) L: Tippy Martinez (1-3) | Fourth | 13 out |
| » Lost to Orioles (49-42), 12-5 | Metropolitan Stadium (23-20) | 43-49 | |
| » W: Steve Stone (15-3) L: Geoff Zahn (8-12) | Fourth | 13 out |
| Tuesday, July 22 |
| » Lost to Orioles (50-42), 8-4 | Metropolitan Stadium (23-21) | 43-50 | Lost 2 |
| » W: Mike Flanagan (10-8) L: Roger Erickson (3-7) | Fourth | 13 out |
| Wednesday, July 23 |
| » Lost to Orioles (51-42), 8-7 | Metropolitan Stadium (23-22) | 43-51 | Lost 3 |
| » W: Scott McGregor (10-5) L: Fernando Arroyo (2-3) S: Tippy Martinez (7) | Fourth | 14 out |
| Friday, July 25 |
| » Lost to Red Sox (48-45), 7-5 | Metropolitan Stadium (23-23) | 43-52 | Lost 4 |
| » W: Win Remmerswaal (2-0) L: Jerry Koosman (8-9) S: Tom Burgmeier (16) | Fourth | 15 out |
| » Defeated Red Sox (48-46), 6-0 | Metropolitan Stadium (24-23) | 44-52 | |
| » W: Geoff Zahn (9-12) L: Steve Renko (5-4) | Fourth | 15 out |
| Saturday, July 26 |
| » Lost to Red Sox (49-46), 5-1 | Metropolitan Stadium (24-24) | 44-53 | |
| » W: Dennis Eckersley (6-9) L: Roger Erickson (3-8) | Fourth | 15 out |
| Sunday, July 27 |
| » Defeated Red Sox (49-47), 5-4 | Metropolitan Stadium (25-24) | 45-53 | |
| » W: Albert Williams (1-0) L: Mike Torrez (5-12) S: Doug Corbett (11) | Fourth | 15 out |
| Monday, July 28 |
| » Lost to Yankees (62-35), 7-6 | Metropolitan Stadium (25-25) | 45-54 | |
| » W: Doug Bird (2-0) L: John Verhoeven (1-3) | Fourth | 15½ out |
| Tuesday, July 29 |
| » Defeated Yankees (62-36), 3-2 | Metropolitan Stadium (26-25) | 46-54 | |
| » W: Geoff Zahn (10-12) L: Luis Tiant (6-5) | Fourth | 15½ out |
| Wednesday, July 30 |
| » Defeated Yankees (62-37), 2-1 | Metropolitan Stadium (27-25) | 47-54 | Won 2 |
| » W: Jerry Koosman (9-9) L: Rich Gossage (4-1) | Fourth | 14½ out |
| Friday, August 1 |
| » Lost to Orioles (56-44), 3-2 | Memorial Stadium (1-3) | 47-55 | |
| » W: Mike Flanagan (11-8) L: Doug Corbett (7-3) | Fourth | 16 out |
| Saturday, August 2 |
| » Lost to Orioles (57-44), 9-2 | Memorial Stadium (1-4) | 47-56 | Lost 2 |
| » W: Scott McGregor (12-5) L: Fernando Arroyo (2-4) | Fourth | 17 out |
| Sunday, August 3 |
| » Lost to Orioles (58-44), 7-2 | Memorial Stadium (1-5) | 47-57 | Lost 3 |
| » W: Jim Palmer (11-8) L: Darrell Jackson (7-6) S: Tim Stoddard (15) | Fourth | 17 out |
| Monday, August 4 |
| » Lost to Athletics (54-53), 11-2 | Oakland-Alameda County Stadium (2-3) | 47-58 | Lost 4 |
| » W: Steve McCatty (9-9) L: Geoff Zahn (10-13) | Fourth | 18 out |
| Tuesday, August 5 |
| » Lost to Athletics (55-53), 3-2 | Oakland-Alameda County Stadium (2-4) | 47-59 | Lost 5 |
| » W: Rick Langford (11-9) L: Jerry Koosman (9-10) | Fourth | 19 out |
| Wednesday, August 6 |
| » Lost to Athletics (56-53), 3-1 | Oakland-Alameda County Stadium (2-5) | 47-60 | Lost 6 |
| » W: Brian Kingman (7-11) L: Roger Erickson (3-9) | Fourth | 20 out |
| Thursday, August 7 |
| » Lost to Angels (42-64), 4-2 | Anaheim Stadium (1-3) | 47-61 | Lost 7 |
| » W: Andy Hassler (3-0) L: Albert Williams (1-1) | Fourth | 20½ out |
| Friday, August 8 |
| » Lost to Angels (43-64), 9-5 | Anaheim Stadium (1-4) | 47-62 | Lost 8 |
| » W: Dave Lemanczyk (4-9) L: Darrell Jackson (7-7) S: John Montague (3) | Fourth | 22 out |
| Saturday, August 9 |
| » Lost to Angels (44-64), 8-2 | Anaheim Stadium (1-5) | 47-63 | Lost 9 |
| » W: Frank Tanana (6-9) L: Geoff Zahn (10-14) | Fifth | 22 out |
| Sunday, August 10 |
| » Defeated Angels (44-65), 5-2 | Anaheim Stadium (2-5) | 48-63 | |
| » W: Jerry Koosman (10-10) L: Jim Barr (0-2) S: Doug Corbett (12) | Fourth | 22 out |
| Tuesday, August 12 |
| » Defeated Athletics (58-56), 3-2 | Metropolitan Stadium (28-25) | 49-63 | Won 2 |
| » W: Doug Corbett (8-3) L: Brian Kingman (7-12) | Fourth | 21½ out |
| Wednesday, August 13 |
| » Lost to Athletics (59-56), 6-2 | Metropolitan Stadium (28-26) | 49-64 | |
| » W: Matt Keough (13-11) L: Fernando Arroyo (2-5) | Fourth | 22½ out |
| Thursday, August 14 |
| » Lost to Athletics (60-56), 2-1 | Metropolitan Stadium (28-27) | 49-65 | Lost 2 |
| » W: Mike Norris (16-7) L: Doug Corbett (8-4) | Fourth | 23 out |
| Friday, August 15 |
| » Lost to Angels (48-65), 5-4 | Metropolitan Stadium (28-28) | 49-66 | Lost 3 |
| » W: Frank Tanana (7-9) L: Geoff Zahn (10-15) S: Andy Hassler (4) | Fourth | 24 out |
| Sunday, August 17 |
| » Defeated Angels (48-66), 8-1 | Metropolitan Stadium (29-28) | 50-66 | |
| » W: Roger Erickson (4-9) L: Jim Barr (0-3) | Fourth | 24 out |
| » Defeated Angels (48-67), 6-5 | Metropolitan Stadium (30-28) | 51-66 | Won 2 |
| » W: Jerry Koosman (11-10) L: Chris Knapp (2-8) S: Doug Corbett (13) | Fourth | 24 out |
| Monday, August 18 |
| » Defeated Angels (48-68), 8-3 | Metropolitan Stadium (31-28) | 52-66 | Won 3 |
| » W: Fernando Arroyo (3-5) L: Dave LaRoche (2-3) | Fourth | 24 out |
| Tuesday, August 19 |
| » Lost to Blue Jays (49-68), 4-3 | Metropolitan Stadium (31-29) | 52-67 | |
| » W: Mike Barlow (2-1) L: Doug Corbett (8-5) S: Ken Schrom (1) | Fourth | 25 out |
| Wednesday, August 20 |
| » Lost to Blue Jays (50-68), 10-4 | Metropolitan Stadium (31-30) | 52-68 | Lost 2 |
| » W: Jackson Todd (1-0) L: Geoff Zahn (10-16) | Fourth | 26 out |
| Thursday, August 21 |
| » Defeated Tigers (61-57), 5-3 | Metropolitan Stadium (32-30) | 53-68 | |
| » W: Albert Williams (2-1) L: Milt Wilcox (11-9) S: Doug Corbett (14) | Fourth | 25½ out |
| » Lost to Tigers (62-57), 4-2 | Metropolitan Stadium (32-31) | 53-69 | |
| » W: Jack Morris (13-11) L: Roger Erickson (4-10) | Fourth | 25½ out |
| Friday, August 22 |
| » Defeated Tigers (62-58), 6-5 | Metropolitan Stadium (33-31) | 54-69 | |
| » W: Fernando Arroyo (4-5) L: Dave Rozema (6-7) | Fourth | 24½ out |
| Saturday, August 23 |
| » Lost to Tigers (63-58), 4-3 | Metropolitan Stadium (33-32) | 54-70 | |
| » W: Bruce Robbins (3-2) L: Darrell Jackson (7-8) S: Dave Rozema (3) | Fourth | 25½ out |
| Sunday, August 24 |
| » Lost to Tigers (64-58), 3-2 | Metropolitan Stadium (33-33) | 54-71 | Lost 2 |
| » W: Dan Schatzeder (8-9) L: Geoff Zahn (10-17) | Fourth | 26½ out |
| Monday, August 25 |
| » Lost to Indians (64-59), 4-3 | Cleveland Stadium (0-4) | 54-72 | Lost 3 |
| » Manager: Johnny Goryl |
| » W: Dan Spillner (12-9) L: Fernando Arroyo (4-6) S: Sid Monge (12) | Fifth | 27½ out |
| Tuesday, August 26 |
| » Defeated Indians (64-60), 5-1 | Cleveland Stadium (1-4) | 55-72 | |
| » W: Roger Erickson (5-10) L: Rick Waits (10-12) | Fourth | 27½ out |
| Wednesday, August 27 |
| » Lost to Indians (65-60), 4-1 | Cleveland Stadium (1-5) | 55-73 | |
| » W: Len Barker (16-8) L: Jerry Koosman (11-11) S: Victor Cruz (10) | Fifth | 28½ out |
| Thursday, August 28 |
| » Game at Exhibition Stadium interrupted in the 15th inning with the score of Twins 5, Blue Jays 5. Completed on August 29. |
| Friday, August 29 |
| » Defeated Blue Jays (52-74), 5-2 | Exhibition Stadium (3-0) | 56-73 | |
| » W: Geoff Zahn (11-17) L: Dave Stieb (11-10) | Fourth | 27½ out |
| » Defeated Blue Jays (52-75), 7-5 | Exhibition Stadium (4-0) | 57-73 | Won 2 |
| » W: John Verhoeven (2-3) L: Jesse Jefferson (4-13) S: Albert Williams (1) | Fourth | 27½ out |
| Saturday, August 30 |
| » Lost to Blue Jays (53-75), 3-2 | Exhibition Stadium (4-1) | 57-74 | |
| » W: Jackson Todd (2-1) L: John Verhoeven (2-4) | Fourth | 27½ out |
| Sunday, August 31 |
| » Lost to Blue Jays (54-75), 7-1 | Exhibition Stadium (4-2) | 57-75 | Lost 2 |
| » W: Jim Clancy (13-10) L: Jerry Koosman (11-12) | Fifth | 28½ out |
| Monday, September 1 |
| » Lost to Indians (68-62), 5-2 | Metropolitan Stadium (33-34) | 57-76 | Lost 3 |
| » W: Len Barker (17-8) L: Albert Williams (2-2) | Fifth | 28½ out |
| Tuesday, September 2 |
| » Defeated Indians (68-63), 5-3 | Metropolitan Stadium (34-34) | 58-76 | |
| » W: Darrell Jackson (8-8) L: Wayne Garland (6-7) S: Doug Corbett (15) | Fourth | 28 out |
| Wednesday, September 3 |
| » Lost to Indians (69-63), 7-1 | Metropolitan Stadium (34-35) | 58-77 | |
| » W: Dan Spillner (14-9) L: Geoff Zahn (11-18) | Fourth | 28 out |
| Friday, September 5 |
| » Lost to Tigers (71-62), 1-0 | Tiger Stadium (1-3) | 58-78 | Lost 2 |
| » W: Dan Schatzeder (9-10) L: Roger Erickson (5-11) | Fifth | 28½ out |
| Saturday, September 6 |
| » Defeated Tigers (71-63), 4-0 | Tiger Stadium (2-3) | 59-78 | |
| » W: Jerry Koosman (12-12) L: Jack Morris (13-13) S: Doug Corbett (16) | Fourth | 27½ out |
| » Major-league debuts: Len Faedo (Twins) |
| Sunday, September 7 |
| » Defeated Tigers (71-64), 3-1 | Tiger Stadium (3-3) | 60-78 | Won 2 |
| » W: Darrell Jackson (9-8) L: Mark Fidrych (1-3) S: Doug Corbett (17) | Fourth | 27½ out |
| Monday, September 8 |
| » Major-league debuts: John Butcher (Rangers) |
| Tuesday, September 9 |
| » Defeated Brewers (73-67), 15-2 | Metropolitan Stadium (35-35) | 61-78 | Won 3 |
| » W: Albert Williams (3-2) L: Lary Sorensen (10-9) | Fourth | 26 out |
| Wednesday, September 10 |
| » Lost to Brewers (74-67), 3-1 | Metropolitan Stadium (35-36) | 61-79 | |
| » W: Paul Mitchell (5-3) L: Roger Erickson (5-12) S: Dave LaPoint (1) | Fourth | 26 out |
| » Major-league debuts: Dave LaPoint (Brewers) |
| Friday, September 12 |
| » Lost to White Sox (60-79), 5-3 | Comiskey Park I (1-3) | 61-80 | Lost 2 |
| » W: Britt Burns (13-12) L: Jerry Koosman (12-13) S: Ed Farmer (26) | Fourth | 26½ out |
| Saturday, September 13 |
| » Defeated White Sox (60-80), 6-5 | Comiskey Park I (2-3) | 62-80 | |
| » W: Geoff Zahn (12-18) L: Steve Trout (8-14) S: Doug Corbett (18) | Fourth | 25½ out |
| Sunday, September 14 |
| » Defeated White Sox (60-81), 3-2 | Comiskey Park I (3-3) | 63-80 | Won 2 |
| » W: Fernando Arroyo (5-6) L: Ross Baumgarten (2-11) S: Doug Corbett (19) | Fourth | 25½ out |
| Wednesday, September 17 |
| » Defeated Brewers (77-68), 3-2 | County Stadium (1-3) | 64-80 | Won 3 |
| » W: Jerry Koosman (13-13) L: Moose Haas (16-13) | Fourth | 24½ out |
| » Defeated Brewers (77-69), 6-1 | County Stadium (2-3) | 65-80 | Won 4 |
| » W: Roger Erickson (6-12) L: Paul Mitchell (5-4) | Fourth | 24½ out |
| Thursday, September 18 |
| » Lost to Brewers (78-69), 9-8 | County Stadium (2-4) | 65-81 | |
| » W: John Flinn (2-1) L: Doug Corbett (8-6) | Fourth | 26 out |
| » Lost to Brewers (79-69), 5-0 | County Stadium (2-5) | 65-82 | Lost 2 |
| » W: Lary Sorensen (11-9) L: Pete Redfern (6-7) | Fourth | 26 out |
| Friday, September 19 |
| » Defeated White Sox (62-84), 6-3 | Metropolitan Stadium (36-36) | 66-82 | |
| » W: Albert Williams (4-2) L: Ed Farmer (7-9) S: Doug Corbett (20) | Fourth | 26 out |
| Saturday, September 20 |
| » Major-league debuts: Ken Phelps (Royals) |
| Sunday, September 21 |
| » Defeated White Sox (62-85), 5-4 | Metropolitan Stadium (37-36) | 67-82 | Won 2 |
| » W: John Verhoeven (3-4) L: Dewey Robinson (0-1) | Fourth | 24 out |
| » Defeated White Sox (62-86), 6-4 | Metropolitan Stadium (38-36) | 68-82 | Won 3 |
| » W: Fernando Arroyo (6-6) L: Richard Dotson (11-10) S: Pete Redfern (1) | Fourth | 24 out |
| Monday, September 22 |
| » Defeated Rangers (71-79), 1-0 | Metropolitan Stadium (39-36) | 69-82 | Won 4 |
| » W: Jerry Koosman (14-13) L: John Butcher (1-3) S: Doug Corbett (21) | Fourth | 23 out |
| Tuesday, September 23 |
| » Defeated Rangers (71-80), 8-2 | Metropolitan Stadium (40-36) | 70-82 | Won 5 |
| » W: Roger Erickson (7-12) L: Ken Clay (2-3) S: Pete Redfern (2) | Fourth | 22 out |
| Wednesday, September 24 |
| » Defeated Rangers (71-81), 9-5 | Metropolitan Stadium (41-36) | 71-82 | Won 6 |
| » W: Albert Williams (5-2) L: Jon Matlack (10-9) | Fourth | 21 out |
| Friday, September 26 |
| » Defeated Royals (92-62), 3-0 | Metropolitan Stadium (42-36) | 72-82 | Won 7 |
| » W: Geoff Zahn (13-18) L: Dennis Leonard (19-11) | Third | 20 out |
| Saturday, September 27 |
| » Defeated Royals (92-63), 8-3 | Metropolitan Stadium (43-36) | 73-82 | Won 8 |
| » W: Jerry Koosman (15-13) L: Larry Gura (18-9) | Third | 19 out |
| Sunday, September 28 |
| » Defeated Royals (92-64), 8-7 | Metropolitan Stadium (44-36) | 74-82 | Won 9 |
| » W: Pete Redfern (7-7) L: Rich Gale (13-9) S: Doug Corbett (22) | Third | 18 out |
| Thursday, October 2 |
| » Defeated Rangers (73-84), 6-3 | Arlington Stadium (2-2) | 75-82 | Won 10 |
| » W: Geoff Zahn (14-18) L: Jon Matlack (10-10) | Third | 18½ out |
| » Defeated Rangers (73-85), 4-1 | Arlington Stadium (3-2) | 76-82 | Won 11 |
| » W: Albert Williams (6-2) L: Fergie Jenkins (12-12) | Third | 18½ out |
| Friday, October 3 |
| » Defeated Royals (95-65), 5-3 | Royals Stadium (3-1) | 77-82 | Won 12 |
| » W: Jerry Koosman (16-13) L: Larry Gura (18-10) S: Doug Corbett (23) | Third | 17½ out |
| Saturday, October 4 |
| » Lost to Royals (96-65), 17-1 | Royals Stadium (3-2) | 77-83 | |
| » W: Dennis Leonard (20-11) L: Roger Erickson (7-13) | Third | 18½ out |
| Sunday, October 5 |
| » Lost to Royals (97-65), 4-0 | Royals Stadium (3-3) | 77-84 | Lost 2 |
| » W: Paul Splittorff (14-11) L: Darrell Jackson (9-9) S: Rich Gale (1) | Third | 19½ out |
Game information provided by Retrosheet (www.retrosheet.org) |