| Monday, January 21 |
| Former Red Sox Gene Rye dies in Park Ridge, IL at the age of 74. |
| Saturday, February 2 |
| Former Red Sox Jack Rothrock dies in San Bernardino, CA at the age of 75. |
| Wednesday, April 9 |
| Former Red Sox Ed Morgan dies in New Orleans, LA at the age of 76. |
| Thursday, April 10 |
| » Lost to Brewers (1-0), 9-5 | County Stadium (0-1) | 0-1 | |
| » W: Reggie Cleveland (1-0) L: Dick Drago (0-1) | Third | 1 out |
| Saturday, April 12 |
| » Lost to Brewers (2-0), 18-1 | County Stadium (0-2) | 0-2 | Lost 2 |
| » W: Lary Sorensen (1-0) L: Mike Torrez (0-1) | Fourth | 2 out |
| » Major-league debuts: Mark Brouhard and Ned Yost (Brewers) Glenn Hoffman and Bruce Hurst (Red Sox) |
| Sunday, April 13 |
| » Defeated Brewers (2-1), 3-1 | County Stadium (1-2) | 1-2 | |
| » W: Bob Stanley (1-0) L: Moose Haas (0-1) | Third | 1 out |
| Monday, April 14 |
| » Defeated Tigers (1-4), 3-1 | Fenway Park (1-0) | 2-2 | Won 2 |
| » W: Dennis Eckersley (1-0) L: Jack Morris (1-1) S: Tom Burgmeier (1) | Second | ½ out |
| Wednesday, April 16 |
| » Defeated Tigers (1-5), 10-9 | Fenway Park (2-0) | 3-2 | Won 3 |
| » W: Steve Renko (1-0) L: Dan Schatzeder (0-2) S: Tom Burgmeier (2) | First | -- |
| Thursday, April 17 |
| » Defeated Tigers (1-6), 5-4 | Fenway Park (3-0) | 4-2 | Won 4 |
| » W: Dick Drago (1-1) L: Aurelio Lopez (0-1) | First | -- |
| Friday, April 18 |
| » Lost to Rangers (6-2), 6-5 | Fenway Park (3-1) | 4-3 | |
| » W: Danny Darwin (1-0) L: Skip Lockwood (0-1) S: Jim Kern (1) | Second | ½ out |
| Saturday, April 19 |
| » Lost to Rangers (7-2), 8-0 | Fenway Park (3-2) | 4-4 | Lost 2 |
| » W: Gaylord Perry (1-1) L: Dennis Eckersley (1-1) | Third | ½ out |
| Sunday, April 20 |
| » Defeated Rangers (7-3), 6-5 | Fenway Park (4-2) | 5-4 | |
| » W: Tom Burgmeier (1-0) L: Jim Kern (1-1) | First | -- |
| Monday, April 21 |
| » Defeated White Sox (7-4), 9-8 | Fenway Park (5-2) | 6-4 | Won 2 |
| » W: Skip Lockwood (1-1) L: Randy Scarbery (0-1) S: Dick Drago (1) | First | -- |
| Tuesday, April 22 |
| » Lost to White Sox (8-4), 2-0 | Fenway Park (5-3) | 6-5 | |
| » W: Britt Burns (2-0) L: Mike Torrez (0-2) S: Mike Proly (1) | Second | ½ out |
| Thursday, April 24 |
| » Lost to White Sox (9-4), 9-3 | Fenway Park (5-4) | 6-6 | Lost 2 |
| » W: Richard Dotson (2-1) L: Bob Stanley (1-1) S: Ed Farmer (5) | Third | ½ out |
| Friday, April 25 |
| » Lost to Tigers (5-9), 11-3 | Tiger Stadium (0-1) | 6-7 | Lost 3 |
| » W: Dan Schatzeder (1-3) L: Dennis Eckersley (1-2) | Third | ½ out |
| Saturday, April 26 |
| » Defeated Tigers (5-10), 12-7 | Tiger Stadium (1-1) | 7-7 | |
| » W: Bruce Hurst (1-0) L: Milt Wilcox (0-2) S: Tom Burgmeier (3) | Second | ½ out |
| Sunday, April 27 |
| » Lost to Tigers (6-10), 8-5 | Tiger Stadium (1-2) | 7-8 | |
| » W: Dave Rozema (2-1) L: Mike Torrez (0-3) S: Aurelio Lopez (2) | Third | 1½ out |
| Monday, April 28 |
| Former Red Sox Bob Porterfield dies in Charlotte, NC at the age of 57. |
| Tuesday, April 29 |
| » Defeated White Sox (11-6), 11-1 | Comiskey Park I (1-0) | 8-8 | |
| » W: Bob Stanley (2-1) L: Ross Baumgarten (1-1) | Third | 1½ out |
| Wednesday, April 30 |
| » Lost to White Sox (12-6), 2-1 | Comiskey Park I (1-1) | 8-9 | |
| » W: Richard Dotson (3-1) L: Dennis Eckersley (1-3) S: Ed Farmer (6) | Third | 1½ out |
| Thursday, May 1 |
| » Defeated White Sox (12-7), 4-3 | Comiskey Park I (2-1) | 9-9 | |
| » W: Bruce Hurst (2-0) L: Steve Trout (1-2) S: Tom Burgmeier (4) | Second | ½ out |
| Friday, May 2 |
| » Defeated Royals (10-9), 6-5 | Royals Stadium (1-0) | 10-9 | Won 2 |
| » W: Skip Lockwood (2-1) L: Dan Quisenberry (1-1) | First | -- |
| Saturday, May 3 |
| » Defeated Royals (10-10), 7-0 | Royals Stadium (2-0) | 11-9 | Won 3 |
| » W: Chuck Rainey (1-0) L: Paul Splittorff (3-1) | First | -- |
| Sunday, May 4 |
| » Lost to Royals (11-10), 5-3 | Royals Stadium (2-1) | 11-10 | |
| » W: Dennis Leonard (1-3) L: Bob Stanley (2-2) S: Dan Quisenberry (3) | Third | 1 out |
| Monday, May 5 |
| » Lost to Rangers (12-10), 11-3 | Arlington Stadium (0-1) | 11-11 | Lost 2 |
| » W: Gaylord Perry (2-1) L: Dennis Eckersley (1-4) | Third | 1½ out |
| Tuesday, May 6 |
| » Lost to Rangers (13-10), 7-2 | Arlington Stadium (0-2) | 11-12 | Lost 3 |
| » W: Doc Medich (2-0) L: Bruce Hurst (2-1) | Third | 2½ out |
| Wednesday, May 7 |
| » Defeated Rangers (13-11), 7-4 | Arlington Stadium (1-2) | 12-12 | |
| » W: Dick Drago (2-1) L: Adrian Devine (0-1) | Second | 2½ out |
| Friday, May 9 |
| » Lost to Royals (13-12), 6-5 | Fenway Park (5-5) | 12-13 | |
| » W: Dennis Leonard (2-3) L: Bob Stanley (2-3) S: Dan Quisenberry (4) | Second | 3½ out |
| Saturday, May 10 |
| » Lost to Royals (14-12), 13-8 | Fenway Park (5-6) | 12-14 | Lost 2 |
| » W: Renie Martin (2-1) L: Dennis Eckersley (1-5) S: Marty Pattin (1) | Third | 3½ out |
| Sunday, May 11 |
| » Defeated Royals (14-13), 5-2 | Fenway Park (6-6) | 13-14 | |
| » W: Chuck Rainey (2-0) L: Rich Gale (0-4) | Fourth | 3½ out |
| Monday, May 12 |
| » Lost to Twins (13-17), 4-3 | Fenway Park (6-7) | 13-15 | |
| » W: Pete Redfern (5-1) L: Mike Torrez (0-4) S: Doug Corbett (3) | Fourth | 3½ out |
| Tuesday, May 13 |
| » Defeated Twins (13-18), 10-5 | Fenway Park (7-7) | 14-15 | |
| » W: Steve Renko (2-0) L: John Verhoeven (0-1) S: Tom Burgmeier (5) | Fourth | 2½ out |
| Wednesday, May 14 |
| » Defeated Twins (13-19), 7-6 | Fenway Park (8-7) | 15-15 | Won 2 |
| » W: Tom Burgmeier (2-0) L: Doug Corbett (3-1) | Fourth | 2½ out |
| Thursday, May 15 |
| » Defeated Indians (11-17), 6-2 | Cleveland Stadium (1-0) | 16-15 | Won 3 |
| » W: Jack Billingham (1-0) L: Rick Waits (2-4) S: Dick Drago (2) | Third | 2 out |
| Friday, May 16 |
| » Defeated Indians (11-18), 2-1 | Cleveland Stadium (2-0) | 17-15 | Won 4 |
| » W: Chuck Rainey (3-0) L: John Denny (2-4) S: Tom Burgmeier (6) | Third | 2 out |
| Saturday, May 17 |
| » Lost to Indians (12-18), 4-3 | Cleveland Stadium (2-1) | 17-16 | |
| » W: Mike Stanton (1-0) L: Keith MacWhorter (0-1) | Third | 3 out |
| Sunday, May 18 |
| » Lost to Indians (13-18), 3-1 | Cleveland Stadium (2-2) | 17-17 | Lost 2 |
| » W: Dan Spillner (3-2) L: Bob Stanley (2-4) S: Sid Monge (3) | Third | 3 out |
| Monday, May 19 |
| » Lost to Blue Jays (19-13), 7-2 | Exhibition Stadium (0-1) | 17-18 | Lost 3 |
| » W: Jim Clancy (3-1) L: Jack Billingham (1-1) | Third | 4 out |
| Tuesday, May 20 |
| » Defeated Blue Jays (19-14), 4-3 | Exhibition Stadium (1-1) | 18-18 | |
| » W: Chuck Rainey (4-0) L: Dave Lemanczyk (2-5) S: Tom Burgmeier (7) | Third | 3 out |
| Wednesday, May 21 |
| » Defeated Blue Jays (19-15), 11-2 | Exhibition Stadium (2-1) | 19-18 | Won 2 |
| » W: Mike Torrez (1-4) L: Jesse Jefferson (2-2) | Third | 3 out |
| Friday, May 23 |
| » Defeated Indians (15-21), 4-1 | Fenway Park (9-7) | 20-18 | Won 3 |
| » W: Bob Stanley (3-4) L: Dan Spillner (3-3) S: Tom Burgmeier (8) | Third | 3½ out |
| Saturday, May 24 |
| » Lost to Indians (16-21), 7-2 | Fenway Park (9-8) | 20-19 | |
| » W: Rick Waits (3-5) L: Jack Billingham (1-2) | Third | 4½ out |
| Sunday, May 25 |
| » Lost to Indians (17-21), 3-2 | Fenway Park (9-9) | 20-20 | Lost 2 |
| » W: John Denny (4-4) L: Chuck Rainey (4-1) | Fourth | 4½ out |
| Monday, May 26 |
| » Lost to Blue Jays (21-18), 3-1 | Fenway Park (9-10) | 20-21 | Lost 3 |
| » W: Jerry Garvin (1-2) L: Dick Drago (2-2) | Fourth | 5½ out |
| Tuesday, May 27 |
| » Defeated Blue Jays (21-19), 5-4 | Fenway Park (10-10) | 21-21 | |
| » W: Steve Renko (3-0) L: Tom Buskey (2-1) | Fourth | 5½ out |
| Wednesday, May 28 |
| » Lost to Blue Jays (22-19), 4-1 | Fenway Park (10-11) | 21-22 | |
| » W: Dave Stieb (5-2) L: Bob Stanley (3-5) S: Joey McLaughlin (3) | Fourth | 5½ out |
| Friday, May 30 |
| » Defeated Brewers (22-20), 5-3 | Fenway Park (11-11) | 22-22 | |
| » W: Chuck Rainey (5-1) L: Lary Sorensen (4-4) S: Tom Burgmeier (9) | Third | 5½ out |
| » Major-league debuts: Dave Stapleton (Red Sox) |
| Saturday, May 31 |
| » Lost to Brewers (23-20), 19-8 | Fenway Park (11-12) | 22-23 | |
| » W: Reggie Cleveland (3-2) L: Mike Torrez (1-5) | Fourth | 6½ out |
| Sunday, June 1 |
| » Lost to Brewers (24-20), 8-5 | Fenway Park (11-13) | 22-24 | Lost 2 |
| » W: John Flinn (1-0) L: Tom Burgmeier (2-1) S: Bill Castro (2) | Fourth | 7½ out |
| Monday, June 2 |
| » Defeated Twins (18-30), 6-2 | Metropolitan Stadium (1-0) | 23-24 | |
| » W: Bob Stanley (4-5) L: Pete Redfern (6-3) | Fourth | 7½ out |
| Tuesday, June 3 |
| » Lost to Twins (19-30), 9-4 | Metropolitan Stadium (1-1) | 23-25 | |
| » W: Jerry Koosman (5-5) L: Jack Billingham (1-3) | Fifth | 7½ out |
| Friday, June 6 |
| » Defeated Athletics (25-26), 14-8 | Oakland-Alameda County Stadium (1-0) | 24-25 | |
| » W: Chuck Rainey (6-1) L: Mike Norris (6-4) | Fourth | 7 out |
| Saturday, June 7 |
| » Lost to Athletics (26-26), 4-1 | Oakland-Alameda County Stadium (1-1) | 24-26 | |
| » W: Matt Keough (7-5) L: Mike Torrez (1-6) | Fifth | 8 out |
| Sunday, June 8 |
| » Defeated Athletics (26-27), 6-1 | Oakland-Alameda County Stadium (2-1) | 25-26 | |
| » W: Tom Burgmeier (3-1) L: Dave Hamilton (0-2) | Fifth | 7 out |
| Monday, June 9 |
| » Lost to Mariners (26-28), 8-7 | Kingdome (0-1) | 25-27 | |
| » W: Dave Heaverlo (4-0) L: Dick Drago (2-3) | Sixth | 8 out |
| Former Red Sox Odell Hale dies in ElDorado, AR at the age of 72. |
| Tuesday, June 10 |
| » Defeated Mariners (26-29), 5-4 | Kingdome (1-1) | 26-27 | |
| » W: Skip Lockwood (3-1) L: Rob Dressler (0-4) | Fifth | 7 out |
| Wednesday, June 11 |
| » Defeated Mariners (26-30), 7-5 | Kingdome (2-1) | 27-27 | Won 2 |
| » W: Chuck Rainey (7-1) L: Jim Beattie (3-6) S: Tom Burgmeier (10) | Third | 7 out |
| Thursday, June 12 |
| » Defeated Angels (21-33), 13-2 | Anaheim Stadium (1-0) | 28-27 | Won 3 |
| » W: Mike Torrez (2-6) L: Dave Frost (4-5) | Third | 6½ out |
| Friday, June 13 |
| » Defeated Angels (21-34), 3-0 | Anaheim Stadium (2-0) | 29-27 | Won 4 |
| » W: Dennis Eckersley (2-5) L: Don Aase (4-5) S: Dick Drago (3) | Third | 6 out |
| Saturday, June 14 |
| » Defeated Angels (21-35), 7-3 | Anaheim Stadium (3-0) | 30-27 | Won 5 |
| » W: Bob Stanley (5-5) L: Alfredo Martinez (1-2) S: Tom Burgmeier (11) | Third | 6 out |
| Former Red Sox Johnny Hodapp dies in Cincinnati, OH at the age of 75. |
| Sunday, June 15 |
| » Defeated Angels (21-36), 6-5 | Anaheim Stadium (4-0) | 31-27 | Won 6 |
| » W: Steve Renko (4-0) L: Frank Tanana (2-7) S: Skip Lockwood (1) | Third | 6 out |
| Monday, June 16 |
| » Lost to Athletics (30-31), 11-8 | Fenway Park (11-14) | 31-28 | |
| » W: Mike Norris (8-4) L: Chuck Rainey (7-2) | Fourth | 7 out |
| Tuesday, June 17 |
| » Defeated Athletics (30-32), 6-2 | Fenway Park (12-14) | 32-28 | |
| » W: Mike Torrez (3-6) L: Matt Keough (7-7) | Third | 7 out |
| Wednesday, June 18 |
| » Defeated Mariners (28-35), 6-2 | Fenway Park (13-14) | 33-28 | Won 2 |
| » W: Dennis Eckersley (3-5) L: Glenn Abbott (6-3) | Second | 7 out |
| Thursday, June 19 |
| » Defeated Mariners (28-36), 2-0 | Fenway Park (14-14) | 34-28 | Won 3 |
| » W: Bob Stanley (6-5) L: Mike Parrott (1-7) | Second | 7 out |
| Friday, June 20 |
| » Lost to Angels (22-40), 20-2 | Fenway Park (14-15) | 34-29 | |
| » W: Frank Tanana (3-7) L: Steve Renko (4-1) | Third | 8 out |
| Saturday, June 21 |
| » Lost to Angels (23-40), 4-2 | Fenway Park (14-16) | 34-30 | Lost 2 |
| » W: Chris Knapp (2-4) L: Chuck Rainey (7-3) S: Andy Hassler (1) | Third | 9 out |
| Sunday, June 22 |
| » Defeated Angels (23-41), 6-3 | Fenway Park (15-16) | 35-30 | |
| » W: Mike Torrez (4-6) L: Jim Barr (0-1) S: Tom Burgmeier (12) | Third | 8 out |
| Monday, June 23 |
| » Defeated Yankees (43-23), 7-2 | Yankee Stadium (1-0) | 36-30 | Won 2 |
| » W: Dennis Eckersley (4-5) L: Ron Guidry (7-4) | Third | 7 out |
| Tuesday, June 24 |
| » Lost to Yankees (44-23), 10-5 | Yankee Stadium (1-1) | 36-31 | |
| » W: Rudy May (5-2) L: John Tudor (0-1) S: Rich Gossage (11) | Third | 8 out |
| Wednesday, June 25 |
| » Defeated Yankees (44-24), 4-3 | Yankee Stadium (2-1) | 37-31 | |
| » W: Tom Burgmeier (4-1) L: Tommy John (10-3) | Third | 7 out |
| Friday, June 27 |
| » Defeated Orioles (37-33), 3-2 | Fenway Park (16-16) | 38-31 | Won 2 |
| » W: Chuck Rainey (8-3) L: Mike Flanagan (7-6) S: Tom Burgmeier (13) | Third | 6 out |
| Saturday, June 28 |
| » Lost to Orioles (38-33), 8-4 | Fenway Park (16-17) | 38-32 | |
| » W: Scott McGregor (8-3) L: Mike Torrez (4-7) | Fourth | 7 out |
| Monday, June 30 |
| » Lost to Yankees (47-25), 6-3 | Fenway Park (16-18) | 38-33 | Lost 2 |
| » W: Tommy John (11-3) L: Bob Stanley (6-6) S: Rich Gossage (12) | Fifth | 8½ out |
| Tuesday, July 1 |
| » Lost to Yankees (48-25), 3-2 | Fenway Park (16-19) | 38-34 | Lost 3 |
| » W: Ed Figueroa (3-2) L: Dennis Eckersley (4-6) S: Ron Davis (5) | Fifth | 9½ out |
| Wednesday, July 2 |
| » Lost to Yankees (49-25), 6-0 | Fenway Park (16-20) | 38-35 | Lost 4 |
| » W: Rudy May (6-3) L: Steve Renko (4-2) | Fifth | 10½ out |
| Thursday, July 3 |
| » Defeated Orioles (41-34), 5-2 | Memorial Stadium (1-0) | 39-35 | |
| » W: Win Remmerswaal (1-0) L: Scott McGregor (8-4) S: Tom Burgmeier (14) | Fifth | 9½ out |
| Friday, July 4 |
| » Lost to Orioles (42-34), 10-3 | Memorial Stadium (1-1) | 39-36 | |
| » W: Steve Stone (12-3) L: Mike Torrez (4-8) S: Tim Stoddard (11) | Fifth | 10½ out |
| Saturday, July 5 |
| » Defeated Orioles (42-35), 1-0 | Memorial Stadium (2-1) | 40-36 | |
| » W: John Tudor (1-1) L: Jim Palmer (8-5) S: Tom Burgmeier (15) | Fifth | 10½ out |
| Sunday, July 6 |
| » Defeated Orioles (42-36), 6-4 | Memorial Stadium (3-1) | 41-36 | Won 2 |
| » W: Dennis Eckersley (5-6) L: Mike Flanagan (8-7) S: Bob Stanley (1) | Fifth | 9½ out |
| Thursday, July 10 |
| » Lost to Brewers (44-34), 2-1 | County Stadium (1-3) | 41-37 | |
| » W: Reggie Cleveland (7-3) L: Mike Torrez (4-9) | Fifth | 10 out |
| » Defeated Brewers (44-35), 7-0 | County Stadium (2-3) | 42-37 | |
| » W: Steve Renko (5-2) L: Lary Sorensen (7-5) | Fifth | 10 out |
| Friday, July 11 |
| » Lost to Brewers (45-35), 7-6 | County Stadium (2-4) | 42-38 | |
| » W: Mike Caldwell (8-5) L: Dennis Eckersley (5-7) S: Bill Castro (5) | Fifth | 10 out |
| Saturday, July 12 |
| » Defeated Tigers (42-36), 9-3 | Fenway Park (17-20) | 43-38 | |
| » W: John Tudor (2-1) L: Dan Petry (5-5) | Fifth | 10 out |
| Sunday, July 13 |
| » Defeated Tigers (42-37), 8-4 | Fenway Park (18-20) | 44-38 | Won 2 |
| » W: Dick Drago (3-3) L: Dave Rozema (4-5) | Third | 10 out |
| » Major-league debuts: Bob Ojeda (Red Sox) |
| Monday, July 14 |
| » Lost to Tigers (43-37), 12-4 | Fenway Park (18-21) | 44-39 | |
| » W: Bruce Robbins (1-0) L: Mike Torrez (4-10) S: Aurelio Lopez (13) | Fourth | 11 out |
| Tuesday, July 15 |
| » Lost to Royals (52-34), 8-4 | Fenway Park (18-22) | 44-40 | Lost 2 |
| » W: Rich Gale (6-7) L: Steve Renko (5-3) | Fifth | 11 out |
| Wednesday, July 16 |
| » Lost to Royals (53-34), 5-1 | Fenway Park (18-23) | 44-41 | Lost 3 |
| » W: Dennis Leonard (9-7) L: Dennis Eckersley (5-8) S: Dan Quisenberry (18) | Fifth | 12 out |
| Thursday, July 17 |
| » Defeated Royals (53-35), 12-4 | Fenway Park (19-23) | 45-41 | |
| » W: John Tudor (3-1) L: Renie Martin (8-7) | Fifth | 12 out |
| Friday, July 18 |
| » Defeated Twins (40-48), 1-0 | Fenway Park (20-23) | 46-41 | Won 2 |
| » W: Mike Torrez (5-10) L: Roger Erickson (3-6) | Fifth | 11 out |
| Saturday, July 19 |
| » Lost to Twins (41-48), 4-0 | Fenway Park (20-24) | 46-42 | |
| » W: Fernando Arroyo (2-2) L: Bob Ojeda (0-1) | Fifth | 12 out |
| Sunday, July 20 |
| » Lost to Twins (42-48), 5-4 | Fenway Park (20-25) | 46-43 | Lost 2 |
| » W: Doug Corbett (7-2) L: Dick Drago (3-4) | Fifth | 12 out |
| Monday, July 21 |
| » Lost to Rangers (45-46), 5-3 | Fenway Park (20-26) | 46-44 | Lost 3 |
| » W: Jon Matlack (7-5) L: Dennis Eckersley (5-9) | Fifth | 12 out |
| Tuesday, July 22 |
| » Lost to Rangers (46-46), 4-3 | Fenway Park (20-27) | 46-45 | Lost 4 |
| » W: Danny Darwin (9-1) L: Mike Torrez (5-11) | Fifth | 12½ out |
| Wednesday, July 23 |
| » Defeated Rangers (46-47), 12-5 | Fenway Park (21-27) | 47-45 | |
| » W: Dick Drago (4-4) L: John Henry Johnson (0-1) | Fifth | 12½ out |
| Friday, July 25 |
| » Defeated Twins (43-52), 7-5 | Metropolitan Stadium (2-1) | 48-45 | Won 2 |
| » W: Win Remmerswaal (2-0) L: Jerry Koosman (8-9) S: Tom Burgmeier (16) | Fifth | 12 out |
| » Lost to Twins (44-52), 6-0 | Metropolitan Stadium (2-2) | 48-46 | |
| » W: Geoff Zahn (9-12) L: Steve Renko (5-4) | Fifth | 12 out |
| Saturday, July 26 |
| » Defeated Twins (44-53), 5-1 | Metropolitan Stadium (3-2) | 49-46 | |
| » W: Dennis Eckersley (6-9) L: Roger Erickson (3-8) | Fifth | 12 out |
| Sunday, July 27 |
| » Lost to Twins (45-53), 5-4 | Metropolitan Stadium (3-3) | 49-47 | |
| » W: Albert Williams (1-0) L: Mike Torrez (5-12) S: Doug Corbett (11) | Fifth | 12 out |
| Tuesday, July 29 |
| » Lost to Royals (61-38), 9-8 | Royals Stadium (2-2) | 49-48 | Lost 2 |
| » W: Dan Quisenberry (7-4) L: Tom Burgmeier (4-2) | Fifth | 12½ out |
| Wednesday, July 30 |
| » Defeated Royals (61-39), 7-1 | Royals Stadium (3-2) | 50-48 | |
| » W: Bob Stanley (7-6) L: Steve Busby (0-2) | Fifth | 11½ out |
| Thursday, July 31 |
| » Lost to Royals (62-39), 13-3 | Royals Stadium (3-3) | 50-49 | |
| » W: Dennis Leonard (11-8) L: Dennis Eckersley (6-10) | Sixth | 12½ out |
| Friday, August 1 |
| » Lost to Rangers (50-51), 7-5 | Arlington Stadium (1-3) | 50-50 | Lost 2 |
| » W: Doc Medich (9-5) L: Win Remmerswaal (2-1) S: Danny Darwin (3) | Sixth | 13½ out |
| Saturday, August 2 |
| » Defeated Rangers (50-52), 1-0 | Arlington Stadium (2-3) | 51-50 | |
| » W: Bob Ojeda (1-1) L: Ed Figueroa (3-4) S: Bob Stanley (2) | Fifth | 13½ out |
| Sunday, August 3 |
| » Defeated Rangers (50-53), 6-4 | Arlington Stadium (3-3) | 52-50 | Won 2 |
| » W: Mike Torrez (6-12) L: Jon Matlack (7-6) S: Skip Lockwood (2) | Fifth | 12½ out |
| Monday, August 4 |
| » Defeated Brewers (55-49), 7-2 | Fenway Park (22-27) | 53-50 | Won 3 |
| » W: Steve Renko (6-4) L: Reggie Cleveland (8-5) S: Bob Stanley (3) | Fifth | 12½ out |
| Tuesday, August 5 |
| » Defeated Brewers (55-50), 3-1 | Fenway Park (23-27) | 54-50 | Won 4 |
| » W: Dennis Eckersley (7-10) L: Mike Caldwell (9-8) S: Tom Burgmeier (17) | Fifth | 11½ out |
| Wednesday, August 6 |
| » Lost to Brewers (56-50), 9-4 | Fenway Park (23-28) | 54-51 | |
| » W: Lary Sorensen (8-7) L: Dick Drago (4-5) S: Bill Castro (7) | Sixth | 12½ out |
| Thursday, August 7 |
| » Defeated Brewers (56-51), 7-3 | Fenway Park (24-28) | 55-51 | |
| » W: Mike Torrez (7-12) L: Paul Mitchell (2-2) S: Bob Stanley (4) | Sixth | 12 out |
| Friday, August 8 |
| » Defeated White Sox (46-61), 4-1 | Fenway Park (25-28) | 56-51 | Won 2 |
| » W: Bill Campbell (1-0) L: Richard Dotson (8-7) S: Bob Stanley (5) | Fifth | 11 out |
| Saturday, August 9 |
| » Lost to White Sox (47-61), 5-4 | Fenway Park (25-29) | 56-52 | |
| » W: Mike Proly (2-6) L: Steve Renko (6-5) S: Ed Farmer (20) | Fifth | 11 out |
| Sunday, August 10 |
| » Defeated White Sox (47-62), 4-3 | Fenway Park (26-29) | 57-52 | |
| » W: Dennis Eckersley (8-10) L: La Marr Hoyt (4-2) S: Bob Stanley (6) | Fifth | 10 out |
| Monday, August 11 |
| » Lost to Tigers (58-49), 8-7 | Tiger Stadium (1-3) | 57-53 | |
| » W: Aurelio Lopez (9-4) L: Tom Burgmeier (4-3) | Fifth | 11 out |
| Tuesday, August 12 |
| » Defeated Tigers (58-50), 5-4 | Tiger Stadium (2-3) | 58-53 | |
| » W: Bill Campbell (2-0) L: Mark Fidrych (0-1) S: Bob Stanley (7) | Fourth | 11 out |
| Wednesday, August 13 |
| » Lost to Tigers (59-50), 2-1 | Tiger Stadium (2-4) | 58-54 | |
| » W: Dan Petry (8-6) L: John Tudor (3-2) S: Aurelio Lopez (17) | Sixth | 11 out |
| Thursday, August 14 |
| » Defeated Tigers (59-51), 3-1 | Tiger Stadium (3-4) | 59-54 | |
| » W: Steve Renko (7-5) L: Dan Schatzeder (6-9) S: Bob Stanley (8) | Sixth | 10 out |
| Friday, August 15 |
| » Defeated White Sox (48-65), 8-5 | Comiskey Park I (3-1) | 60-54 | Won 2 |
| » W: Dennis Eckersley (9-10) L: Mike Proly (2-7) S: Bob Stanley (9) | Fifth | 10 out |
| Tuesday, August 19 |
| » Defeated Athletics (62-58), 7-5 | Oakland-Alameda County Stadium (3-1) | 61-54 | Won 3 |
| » W: Bob Stanley (8-6) L: Craig Minetto (0-2) S: Tom Burgmeier (18) | Fourth | 9½ out |
| Wednesday, August 20 |
| » Lost to Athletics (63-58), 2-1 | Oakland-Alameda County Stadium (3-2) | 61-55 | |
| » W: Mike Norris (17-7) L: Dennis Eckersley (9-11) S: Bob Lacey (4) | Fourth | 10½ out |
| Thursday, August 21 |
| » Defeated Athletics (63-59), 5-1 | Oakland-Alameda County Stadium (4-2) | 62-55 | |
| » W: John Tudor (4-2) L: Rick Langford (13-10) | Fourth | 9½ out |
| Friday, August 22 |
| » Defeated Mariners (43-78), 1-0 | Kingdome (3-1) | 63-55 | Won 2 |
| » W: Steve Renko (8-5) L: Jim Beattie (4-11) S: Bob Stanley (10) | Fourth | 8½ out |
| Saturday, August 23 |
| » Lost to Mariners (44-78), 3-1 | Kingdome (3-2) | 63-56 | |
| » W: Rob Dressler (3-6) L: Bruce Hurst (2-2) S: Shane Rawley (11) | Fourth | 9½ out |
| Sunday, August 24 |
| » Defeated Mariners (44-79), 10-7 | Kingdome (4-2) | 64-56 | |
| » W: Bill Campbell (3-0) L: Rick Honeycutt (8-15) | Third | 9½ out |
| Monday, August 25 |
| » Defeated Angels (49-74), 4-2 | Anaheim Stadium (5-0) | 65-56 | Won 2 |
| » W: Bob Stanley (9-6) L: Mark Clear (9-11) | Third | 8½ out |
| Tuesday, August 26 |
| » Defeated Angels (49-75), 5-1 | Anaheim Stadium (6-0) | 66-56 | Won 3 |
| » W: John Tudor (5-2) L: Chris Knapp (2-10) S: Bob Stanley (11) | Third | 7½ out |
| Thursday, August 28 |
| » Defeated Athletics (65-63), 3-2 | Fenway Park (27-29) | 67-56 | Won 4 |
| » W: Tom Burgmeier (5-3) L: Steve McCatty (10-12) S: Bob Stanley (12) | Third | 7½ out |
| Friday, August 29 |
| » Defeated Athletics (65-64), 6-3 | Fenway Park (28-29) | 68-56 | Won 5 |
| » W: Mike Torrez (8-12) L: Brian Kingman (7-15) S: Tom Burgmeier (19) | Third | 7½ out |
| Saturday, August 30 |
| » Defeated Athletics (65-65), 7-6 | Fenway Park (29-29) | 69-56 | Won 6 |
| » W: Bill Campbell (4-0) L: Bob Lacey (2-2) | Third | 7½ out |
| Sunday, August 31 |
| » Defeated Athletics (65-66), 5-1 | Fenway Park (30-29) | 70-56 | Won 7 |
| » W: John Tudor (6-2) L: Mike Norris (18-8) S: Bob Stanley (13) | Third | 6½ out |
| Monday, September 1 |
| » Defeated Angels (51-78), 4-3 | Fenway Park (31-29) | 71-56 | Won 8 |
| » W: Dick Drago (5-5) L: Dave Frost (4-7) S: Tom Burgmeier (20) | Third | 6½ out |
| Tuesday, September 2 |
| » Defeated Angels (51-79), 10-2 | Fenway Park (32-29) | 72-56 | Won 9 |
| » W: Steve Renko (9-5) L: Jim Dorsey (0-1) | Third | 6½ out |
| » Major-league debuts: Steve Crawford and Chico Walker (Red Sox) Jim Dorsey (Angels) |
| Wednesday, September 3 |
| » Lost to Angels (52-79), 7-2 | Fenway Park (32-30) | 72-57 | |
| » W: Alfredo Martinez (5-6) L: Mike Torrez (8-13) | Third | 7½ out |
| Thursday, September 4 |
| » Lost to Mariners (48-85), 7-4 | Fenway Park (32-31) | 72-58 | Lost 2 |
| » W: Glenn Abbott (10-10) L: Dennis Eckersley (9-12) S: Manny Sarmiento (1) | Third | 8½ out |
| » Major-league debuts: Luis Aponte (Red Sox) |
| Friday, September 5 |
| » Lost to Mariners (49-85), 4-2 | Fenway Park (32-32) | 72-59 | Lost 3 |
| » W: Floyd Bannister (8-10) L: John Tudor (6-3) S: Shane Rawley (13) | Third | 9½ out |
| Saturday, September 6 |
| » Defeated Mariners (49-86), 5-1 | Fenway Park (33-32) | 73-59 | |
| » W: Dick Drago (6-5) L: Mike Parrott (1-13) S: Tom Burgmeier (21) | Third | 9½ out |
| Sunday, September 7 |
| » Lost to Mariners (50-86), 12-6 | Fenway Park (33-33) | 73-60 | |
| » W: Byron McLaughlin (2-6) L: Steve Renko (9-6) | Third | 10½ out |
| » Major-league debuts: Rich Gedman (Red Sox) |
| Monday, September 8 |
| » Defeated Indians (70-66), 10-4 | Cleveland Stadium (3-2) | 74-60 | |
| » W: Mike Torrez (9-13) L: Dan Spillner (14-10) | Third | 10½ out |
| Tuesday, September 9 |
| » Defeated Indians (70-67), 4-3 | Cleveland Stadium (4-2) | 75-60 | Won 2 |
| » W: Dennis Eckersley (10-12) L: Victor Cruz (5-7) S: Tom Burgmeier (22) | Third | 9½ out |
| Wednesday, September 10 |
| » Lost to Indians (71-67), 7-4 | Cleveland Stadium (4-3) | 75-61 | |
| » W: Rick Waits (11-13) L: John Tudor (6-4) | Third | 10½ out |
| Thursday, September 11 |
| » Lost to Yankees (88-52), 8-5 | Fenway Park (33-34) | 75-62 | Lost 2 |
| » W: Ron Davis (7-3) L: Tom Burgmeier (5-4) | Third | 11½ out |
| Friday, September 12 |
| » Lost to Yankees (89-52), 4-2 | Fenway Park (33-35) | 75-63 | Lost 3 |
| » W: Rudy May (14-5) L: Steve Renko (9-7) S: Rich Gossage (27) | Third | 12½ out |
| Saturday, September 13 |
| » Lost to Yankees (90-52), 4-3 | Fenway Park (33-36) | 75-64 | Lost 4 |
| » W: Tommy John (21-7) L: Mike Torrez (9-14) | Third | 13½ out |
| Sunday, September 14 |
| » Lost to Yankees (91-52), 5-3 | Fenway Park (33-37) | 75-65 | Lost 5 |
| » W: Ron Davis (8-3) L: Dennis Eckersley (10-13) | Third | 14½ out |
| Tuesday, September 16 |
| » Defeated Indians (73-70), 9-5 | Fenway Park (34-37) | 76-65 | |
| » W: John Tudor (7-4) L: Ross Grimsley (6-9) S: Bob Stanley (14) | Third | 14½ out |
| » Major-league debuts: Reid Nichols (Red Sox) |
| Wednesday, September 17 |
| » Lost to Indians (74-70), 6-5 | Fenway Park (34-38) | 76-66 | |
| » W: Dan Spillner (15-10) L: Mike Torrez (9-15) | Third | 15 out |
| Thursday, September 18 |
| » Defeated Indians (74-71), 8-3 | Fenway Park (35-38) | 77-66 | |
| » W: Steve Crawford (1-0) L: Wayne Garland (6-9) | Third | 14½ out |
| Friday, September 19 |
| » Lost to Yankees (94-53), 2-1 | Yankee Stadium (2-2) | 77-67 | |
| » W: Luis Tiant (7-9) L: Steve Renko (9-8) S: Rich Gossage (29) | Fourth | 15½ out |
| Saturday, September 20 |
| » Defeated Yankees (94-54), 4-1 | Yankee Stadium (3-2) | 78-67 | |
| » W: Dennis Eckersley (11-13) L: Gaylord Perry (9-12) | Fourth | 14½ out |
| Sunday, September 21 |
| » Lost to Yankees (95-54), 3-0 | Yankee Stadium (3-3) | 78-68 | |
| » W: Ron Guidry (15-10) L: John Tudor (7-5) S: Rich Gossage (30) | Fourth | 15½ out |
| Monday, September 22 |
| » Defeated Orioles (91-59), 5-3 | Memorial Stadium (4-1) | 79-68 | |
| » W |
