| Monday, January 21 |
| Former Pirate Clyde Barnhart dies in Hagerstown, MD at the age of 85. |
| Wednesday, March 5 |
| Former Pirate Les Fleming dies in Cleveland, TX at the age of 65. |
| Thursday, April 10 |
| » Lost to Cardinals (1-0), 1-0 | Busch Stadium II (0-1) | 0-1 | |
| » W: Pete Vuckovich (1-0) L: Bert Blyleven (0-1) | Third | 1 out |
| Friday, April 11 |
| » Defeated Cardinals (1-1), 4-3 | Busch Stadium II (1-1) | 1-1 | |
| » W: Grant Jackson (1-0) L: Don Hood (0-1) | Second | ½ out |
| Saturday, April 12 |
| » Defeated Cardinals (1-2), 7-2 | Busch Stadium II (2-1) | 2-1 | Won 2 |
| » W: Jim Bibby (1-0) L: John Fulgham (0-1) | Second | ½ out |
| Sunday, April 13 |
| » Defeated Cardinals (1-3), 3-0 | Busch Stadium II (3-1) | 3-1 | Won 3 |
| » W: Jim Rooker (1-0) L: Silvio Martinez (0-1) S: Grant Jackson (1) | First | -- |
| Monday, April 14 |
| » Defeated Cubs (2-3), 5-4 | Three Rivers Stadium (1-0) | 4-1 | Won 4 |
| » W: Kent Tekulve (1-0) L: Bruce Sutter (0-1) | First | -- |
| Future Pirate John Van Benschoten is born in San Diego, CA. |
| Thursday, April 17 |
| » Lost to Cardinals (3-4), 12-9 | Three Rivers Stadium (1-1) | 4-2 | |
| » W: Bob Sykes (1-0) L: John Candelaria (0-1) | First | -- |
| » Major-league debuts: Rod Scurry (Pirates) |
| Friday, April 18 |
| » Defeated Cardinals (3-5), 12-10 | Three Rivers Stadium (2-1) | 5-2 | |
| » W: Grant Jackson (2-0) L: Darold Knowles (0-1) S: Kent Tekulve (1) | First | -- |
| Saturday, April 19 |
| » Lost to Cardinals (4-5), 2-1 | Three Rivers Stadium (2-2) | 5-3 | |
| » W: John Fulgham (1-1) L: Dave Roberts (0-1) | First | -- |
| Sunday, April 20 |
| » Defeated Cardinals (4-6), 6-3 | Three Rivers Stadium (3-2) | 6-3 | |
| » W: Jim Rooker (2-0) L: Pete Vuckovich (2-1) S: Kent Tekulve (2) | First | -- |
| Monday, April 21 |
| » Defeated Expos (4-5), 7-1 | Stade Olympique (1-0) | 7-3 | Won 2 |
| » W: John Candelaria (1-1) L: Ross Grimsley (0-1) | First | -- |
| Former Pirate Joe Page dies in Latrobe, PA at the age of 63. |
| Tuesday, April 22 |
| » Defeated Expos (4-6), 5-3 | Stade Olympique (2-0) | 8-3 | Won 3 |
| » W: Jim Bibby (2-0) L: Scott Sanderson (1-1) S: Kent Tekulve (3) | First | -- |
| Wednesday, April 23 |
| » Lost to Expos (5-6), 3-2 | Stade Olympique (2-1) | 8-4 | |
| » W: Steve Rogers (2-2) L: Bert Blyleven (0-2) | First | -- |
| Friday, April 25 |
| » Lost to Cubs (7-4), 5-3 | Wrigley Field (0-1) | 8-5 | Lost 2 |
| » W: Rick Reuschel (2-1) L: Jim Rooker (2-1) S: Bruce Sutter (5) | Second | 1 out |
| Saturday, April 26 |
| » Defeated Cubs (7-5), 9-2 | Wrigley Field (1-1) | 9-5 | |
| » W: John Candelaria (2-1) L: Dennis Lamp (2-1) | First | -- |
| Monday, April 28 |
| Former Pirate Bob Porterfield dies in Charlotte, NC at the age of 57. |
| Tuesday, April 29 |
| » Defeated Expos (6-9), 5-4 | Three Rivers Stadium (4-2) | 10-5 | Won 2 |
| » W: Eddie Solomon (1-0) L: Elias Sosa (2-1) | First | -- |
| Wednesday, April 30 |
| » Defeated Expos (6-10), 5-0 | Three Rivers Stadium (5-2) | 11-5 | Won 3 |
| » W: Jim Bibby (3-0) L: Bill Lee (0-3) | First | -- |
| Thursday, May 1 |
| » Defeated Expos (6-11), 2-1 | Three Rivers Stadium (6-2) | 12-5 | Won 4 |
| » W: Kent Tekulve (2-0) L: Woodie Fryman (0-1) | First | -- |
| Friday, May 2 |
| » Lost to Braves (7-12), 6-1 | Three Rivers Stadium (6-3) | 12-6 | |
| » W: Phil Niekro (1-4) L: Jim Rooker (2-2) | First | -- |
| Saturday, May 3 |
| » Lost to Braves (8-12), 3-1 | Three Rivers Stadium (6-4) | 12-7 | Lost 2 |
| » W: Al Hrabosky (2-1) L: Grant Jackson (2-1) | Second | 1 out |
| Sunday, May 4 |
| » Defeated Braves (8-13), 13-4 | Three Rivers Stadium (7-4) | 13-7 | |
| » W: Jim Bibby (4-0) L: Tommy Boggs (0-1) | First | -- |
| Tuesday, May 6 |
| » Defeated Dodgers (14-10), 2-1 | Three Rivers Stadium (8-4) | 14-7 | Won 2 |
| » W: Kent Tekulve (3-0) L: Steve Howe (1-1) | First | -- |
| Wednesday, May 7 |
| » Defeated Dodgers (14-11), 7-6 | Three Rivers Stadium (9-4) | 15-7 | Won 3 |
| » W: Kent Tekulve (4-0) L: Charlie Hough (0-2) | First | -- |
| » Major-league debuts: Pascual Perez (Pirates) |
| Friday, May 9 |
| » Defeated Padres (13-14), 4-3 | San Diego/Jack Murphy Stadium (1-0) | 16-7 | Won 4 |
| » W: Kent Tekulve (5-0) L: Rollie Fingers (2-3) | First | -- |
| Saturday, May 10 |
| » Defeated Padres (13-15), 9-5 | San Diego/Jack Murphy Stadium (2-0) | 17-7 | Won 5 |
| » W: Don Robinson (1-0) L: Eric Rasmussen (1-4) S: Enrique Romo (1) | First | -- |
| Sunday, May 11 |
| » Lost to Padres (14-15), 5-0 | San Diego/Jack Murphy Stadium (2-1) | 17-8 | |
| » W: Randy Jones (3-2) L: John Candelaria (2-2) | First | -- |
| Tuesday, May 13 |
| » Lost to Giants (11-20), 5-0 | Candlestick Park (0-1) | 17-9 | Lost 2 |
| » W: Vida Blue (4-2) L: Bert Blyleven (0-3) | First | -- |
| Wednesday, May 14 |
| » Defeated Giants (11-21), 3-2 | Candlestick Park (1-1) | 18-9 | |
| » W: Jim Bibby (5-0) L: Bob Knepper (2-5) S: Kent Tekulve (4) | First | -- |
| Thursday, May 15 |
| » Defeated Giants (11-22), 3-2 | Candlestick Park (2-1) | 19-9 | Won 2 |
| » W: Enrique Romo (1-0) L: Tom Griffin (0-1) | First | -- |
| Friday, May 16 |
| » Lost to Dodgers (19-13), 8-6 | Dodger Stadium (0-1) | 19-10 | |
| » W: Jerry Reuss (4-0) L: Kent Tekulve (5-1) S: Rick Sutcliffe (1) | First | -- |
| Saturday, May 17 |
| » Lost to Dodgers (20-13), 3-1 | Dodger Stadium (0-2) | 19-11 | Lost 2 |
| » W: Don Sutton (4-0) L: Bert Blyleven (0-4) S: Steve Howe (4) | First | -- |
| Sunday, May 18 |
| » Lost to Dodgers (21-13), 2-0 | Dodger Stadium (0-3) | 19-12 | Lost 3 |
| » W: Bob Welch (3-1) L: Jim Bibby (5-1) S: Steve Howe (5) | First | -- |
| Wednesday, May 21 |
| » Defeated Padres (18-18), 4-3 | Three Rivers Stadium (10-4) | 20-12 | |
| » W: Enrique Romo (2-0) L: Rollie Fingers (4-4) | First | -- |
| » Defeated Padres (18-19), 3-2 | Three Rivers Stadium (11-4) | 21-12 | Won 2 |
| » W: Grant Jackson (3-1) L: John Curtis (3-3) S: Kent Tekulve (5) | First | -- |
| Thursday, May 22 |
| » Lost to Padres (19-19), 6-4 | Three Rivers Stadium (11-5) | 21-13 | |
| » W: Bob Shirley (3-1) L: Kent Tekulve (5-2) S: Rollie Fingers (5) | First | -- |
| Friday, May 23 |
| » Defeated Giants (16-23), 5-4 | Three Rivers Stadium (12-5) | 22-13 | |
| » W: Grant Jackson (4-1) L: Al Holland (1-1) | First | -- |
| Saturday, May 24 |
| » Lost to Giants (17-23), 10-9 | Three Rivers Stadium (12-6) | 22-14 | |
| » W: Tom Griffin (1-1) L: Rod Scurry (0-1) | First | -- |
| Sunday, May 25 |
| » Lost to Giants (18-23), 5-2 | Three Rivers Stadium (12-7) | 22-15 | Lost 2 |
| » W: Vida Blue (7-2) L: John Candelaria (2-3) | First | -- |
| Monday, May 26 |
| » Lost to Phillies (21-15), 7-6 | Veteran's Stadium (0-1) | 22-16 | Lost 3 |
| » W: Ron Reed (3-0) L: Kent Tekulve (5-3) | Second | 1 out |
| » Major-league debuts: Bob Walk (Phillies) |
| Tuesday, May 27 |
| » Defeated Phillies (21-16), 3-2 | Veteran's Stadium (1-1) | 23-16 | |
| » W: Enrique Romo (3-0) L: Dickie Noles (0-2) S: Kent Tekulve (6) | First | -- |
| Wednesday, May 28 |
| » Lost to Phillies (22-16), 6-3 | Veteran's Stadium (1-2) | 23-17 | |
| » W: Randy Lerch (1-6) L: Don Robinson (1-1) S: Ron Reed (2) | Second | 1 out |
| Thursday, May 29 |
| » Defeated Phillies (22-17), 5-4 | Veteran's Stadium (2-2) | 24-17 | |
| » W: Eddie Solomon (2-0) L: Dick Ruthven (5-4) S: Enrique Romo (2) | First | -- |
| Friday, May 30 |
| » Lost to Mets (19-22), 5-1 | Three Rivers Stadium (12-8) | 24-18 | |
| » W: Pat Zachry (1-2) L: John Candelaria (2-4) | First | -- |
| Saturday, May 31 |
| » Defeated Mets (19-23), 5-0 | Three Rivers Stadium (13-8) | 25-18 | |
| » W: Bert Blyleven (1-4) L: Craig Swan (3-4) | First | -- |
| Sunday, June 1 |
| » Defeated Mets (19-24), 13-3 | Three Rivers Stadium (14-8) | 26-18 | Won 2 |
| » W: Jim Bibby (6-1) L: Pete Falcone (3-4) | First | -- |
| » Major-league debuts: Vance Law (Pirates) |
| Monday, June 2 |
| » Defeated Phillies (23-20), 9-3 | Three Rivers Stadium (15-8) | 27-18 | Won 3 |
| » W: Don Robinson (2-1) L: Randy Lerch (1-7) | First | -- |
| Tuesday, June 3 |
| » Defeated Phillies (23-21), 4-3 | Three Rivers Stadium (16-8) | 28-18 | Won 4 |
| » W: Grant Jackson (5-1) L: Tug McGraw (0-2) | First | -- |
| Wednesday, June 4 |
| » Lost to Phillies (24-21), 4-3 | Three Rivers Stadium (16-9) | 28-19 | |
| » W: Steve Carlton (10-2) L: John Candelaria (2-5) | First | -- |
| Friday, June 6 |
| » Lost to Mets (21-26), 9-4 | Shea Stadium (0-1) | 28-20 | Lost 2 |
| » W: Tom Hausman (1-1) L: Bert Blyleven (1-5) | First | -- |
| Saturday, June 7 |
| » Lost to Mets (22-26), 6-5 | Shea Stadium (0-2) | 28-21 | Lost 3 |
| » W: Neil Allen (3-4) L: Grant Jackson (5-2) | Second | 1 out |
| Sunday, June 8 |
| » Lost to Mets (23-26), 6-4 | Shea Stadium (0-3) | 28-22 | Lost 4 |
| » W: Ray Burris (4-4) L: Enrique Romo (3-1) S: Ed Glynn (1) | Second | 1 out |
| » Defeated Mets (23-27), 3-0 | Shea Stadium (1-3) | 29-22 | |
| » W: Eddie Solomon (3-0) L: Mark Bomback (3-1) S: Kent Tekulve (7) | Second | 1 out |
| Tuesday, June 10 |
| » Defeated Reds (30-24), 5-3 | Riverfront Stadium (1-0) | 30-22 | Won 2 |
| » W: John Candelaria (3-5) L: Mario Soto (0-1) S: Kent Tekulve (8) | Second | 1 out |
| Wednesday, June 11 |
| » Lost to Reds (31-24), 3-2 | Riverfront Stadium (1-1) | 30-23 | |
| » W: Frank Pastore (8-2) L: Bert Blyleven (1-6) | Second | 2 out |
| Thursday, June 12 |
| » Defeated Reds (31-25), 10-6 | Riverfront Stadium (2-1) | 31-23 | |
| » W: Jim Bibby (7-1) L: Mike LaCoss (4-6) S: Enrique Romo (3) | Second | 2 out |
| Friday, June 13 |
| » Defeated Astros (33-22), 5-3 | Three Rivers Stadium (17-9) | 32-23 | Won 2 |
| » W: Eddie Solomon (4-0) L: Joe Niekro (6-5) S: Kent Tekulve (9) | Second | 2 out |
| Saturday, June 14 |
| » Lost to Astros (34-22), 7-3 | Three Rivers Stadium (17-10) | 32-24 | |
| » W: Nolan Ryan (4-5) L: Don Robinson (2-2) S: Frank LaCorte (6) | Second | 2 out |
| Sunday, June 15 |
| » Defeated Astros (34-23), 4-1 | Three Rivers Stadium (18-10) | 33-24 | |
| » W: John Candelaria (4-5) L: Ken Forsch (7-5) | Second | 1 out |
| Monday, June 16 |
| » Defeated Reds (32-28), 5-3 | Three Rivers Stadium (19-10) | 34-24 | Won 2 |
| » W: Bert Blyleven (2-6) L: Frank Pastore (8-3) S: Grant Jackson (2) | Second | 1 out |
| Tuesday, June 17 |
| » Lost to Reds (33-28), 4-3 | Three Rivers Stadium (19-11) | 34-25 | |
| » W: Paul Moskau (5-1) L: Enrique Romo (3-2) | Second | 1 out |
| Wednesday, June 18 |
| » Lost to Braves (25-34), 3-2 | Atlanta-Fulton County Stadium (0-1) | 34-26 | Lost 2 |
| » W: Gene Garber (2-4) L: Kent Tekulve (5-4) | Third | 1½ out |
| » Lost to Braves (26-34), 5-4 | Atlanta-Fulton County Stadium (0-2) | 34-27 | Lost 3 |
| » W: Rick Camp (1-2) L: Enrique Romo (3-3) S: Gene Garber (4) | Third | 1½ out |
| Thursday, June 19 |
| » Lost to Braves (27-34), 4-3 | Atlanta-Fulton County Stadium (0-3) | 34-28 | Lost 4 |
| » W: Rick Matula (5-5) L: Don Robinson (2-3) S: Larry Bradford (3) | Third | 1½ out |
| Friday, June 20 |
| » Lost to Astros (39-23), 6-4 | Astrodome (0-1) | 34-29 | Lost 5 |
| » W: Ken Forsch (8-5) L: John Candelaria (4-6) S: Joe Sambito (7) | Third | 1½ out |
| Saturday, June 21 |
| » Lost to Astros (40-23), 4-2 | Astrodome (0-2) | 34-30 | Lost 6 |
| » W: Vern Ruhle (5-1) L: Bert Blyleven (2-7) S: Joe Sambito (8) | Third | 2½ out |
| Sunday, June 22 |
| » Defeated Astros (40-24), 2-1 | Astrodome (1-2) | 35-30 | |
| » W: Jim Bibby (8-1) L: Joe Niekro (7-6) S: Grant Jackson (3) | Third | 2½ out |
| Monday, June 23 |
| » Lost to Cardinals (26-40), 6-1 | Busch Stadium II (3-2) | 35-31 | |
| » W: Jim Kaat (2-5) L: Eddie Solomon (4-1) | Third | 3 out |
| Tuesday, June 24 |
| » Lost to Cardinals (27-40), 3-2 | Busch Stadium II (3-3) | 35-32 | Lost 2 |
| » W: Bob Sykes (2-6) L: Rick Rhoden (0-1) | Third | 4 out |
| Wednesday, June 25 |
| » Lost to Cardinals (28-40), 4-1 | Busch Stadium II (3-4) | 35-33 | Lost 3 |
| » W: Don Hood (2-2) L: John Candelaria (4-7) S: Kim Seaman (2) | Third | 4 out |
| Friday, June 27 |
| » Defeated Expos (38-28), 6-4 | Stade Olympique (3-1) | 36-33 | |
| » W: Enrique Romo (4-3) L: Steve Rogers (9-6) S: Don Robinson (1) | Third | 3½ out |
| Saturday, June 28 |
| » Defeated Expos (38-29), 4-3 | Stade Olympique (4-1) | 37-33 | Won 2 |
| » W: Jim Bibby (9-1) L: Charlie Lea (2-2) S: Enrique Romo (4) | Second | 2½ out |
| Sunday, June 29 |
| » Lost to Expos (39-29), 4-1 | Stade Olympique (4-2) | 37-34 | |
| » W: David Palmer (5-1) L: Eddie Solomon (4-2) S: Fred Norman (3) | Third | 3½ out |
| Monday, June 30 |
| » Defeated Cardinals (31-42), 5-4 | Three Rivers Stadium (20-11) | 38-34 | |
| » W: Enrique Romo (5-3) L: Don Hood (2-3) | Third | 2½ out |
| Tuesday, July 1 |
| » Defeated Cardinals (31-43), 3-2 | Three Rivers Stadium (21-11) | 39-34 | Won 2 |
| » W: Grant Jackson (6-2) L: Jim Kaat (2-6) | Third | 1½ out |
| Wednesday, July 2 |
| » Lost to Cardinals (32-43), 7-5 | Three Rivers Stadium (21-12) | 39-35 | |
| » W: John Urrea (2-0) L: Rod Scurry (0-2) | Third | 2½ out |
| Thursday, July 3 |
| » Defeated Cubs (31-41), 5-3 | Three Rivers Stadium (22-12) | 40-35 | |
| » W: Jim Bibby (10-1) L: Mike Krukow (6-9) S: Grant Jackson (4) | Third | 1½ out |
| Friday, July 4 |
| » Lost to Cubs (32-41), 4-2 | Three Rivers Stadium (22-13) | 40-36 | |
| » W: Lynn McGlothen (6-5) L: Eddie Solomon (4-3) S: Bruce Sutter (19) | Third | 2½ out |
| » Lost to Cubs (33-41), 2-1 | Three Rivers Stadium (22-14) | 40-37 | Lost 2 |
| » W: Doug Capilla (2-0) L: Don Robinson (2-4) S: Dick Tidrow (4) | Third | 2½ out |
| Saturday, July 5 |
| » Defeated Cubs (33-42), 5-4 | Three Rivers Stadium (23-14) | 41-37 | |
| » W: John Candelaria (5-7) L: Willie Hernandez (1-8) S: Enrique Romo (5) | Third | 1½ out |
| Sunday, July 6 |
| » Defeated Cubs (33-43), 5-4 | Three Rivers Stadium (24-14) | 42-37 | Won 2 |
| » W: Jim Bibby (11-1) L: Dennis Lamp (8-7) | Third | 1½ out |
| Thursday, July 10 |
| » Lost to Mets (39-40), 2-0 | Shea Stadium (1-4) | 42-38 | |
| » W: Pat Zachry (3-5) L: John Candelaria (5-8) | Third | 2½ out |
| Friday, July 11 |
| » Defeated Mets (39-41), 4-2 | Shea Stadium (2-4) | 43-38 | |
| » W: Bert Blyleven (3-7) L: Craig Swan (5-7) S: Kent Tekulve (10) | Second | 1½ out |
| Saturday, July 12 |
| » Lost to Phillies (44-35), 5-4 | Veteran's Stadium (2-3) | 43-39 | |
| » W: Kevin Saucier (4-3) L: Kent Tekulve (5-5) | Third | 2½ out |
| Sunday, July 13 |
| » Defeated Phillies (44-36), 7-3 | Veteran's Stadium (3-3) | 44-39 | |
| » W: Don Robinson (3-4) L: Nino Espinosa (0-1) S: Kent Tekulve (11) | Third | 2 out |
| Monday, July 14 |
| » Defeated Phillies (44-37), 13-11 | Veteran's Stadium (4-3) | 45-39 | Won 2 |
| » W: Grant Jackson (7-2) L: Ron Reed (6-3) | Third | 1½ out |
| Tuesday, July 15 |
| » Defeated Giants (43-44), 5-2 | Three Rivers Stadium (25-14) | 46-39 | Won 3 |
| » W: John Candelaria (6-8) L: Bob Knepper (8-10) S: Kent Tekulve (12) | Second | 1½ out |
| Wednesday, July 16 |
| » Defeated Giants (43-45), 3-1 | Three Rivers Stadium (26-14) | 47-39 | Won 4 |
| » W: Bert Blyleven (4-7) L: Ed Whitson (8-9) S: Grant Jackson (5) | Second | 1½ out |
| Thursday, July 17 |
| » Defeated Giants (43-46), 3-2 | Three Rivers Stadium (27-14) | 48-39 | Won 5 |
| » W: Kent Tekulve (6-5) L: Al Holland (2-2) | Second | 1½ out |
| Friday, July 18 |
| » Defeated Dodgers (50-39), 6-4 | Three Rivers Stadium (28-14) | 49-39 | Won 6 |
| » W: Rick Rhoden (1-1) L: Bob Welch (9-4) S: Enrique Romo (6) | Second | 1½ out |
| Saturday, July 19 |
| » Defeated Dodgers (50-40), 7-3 | Three Rivers Stadium (29-14) | 50-39 | Won 7 |
| » W: Eddie Solomon (5-3) L: Rick Sutcliffe (3-7) | Second | 1 out |
| Sunday, July 20 |
| » Lost to Dodgers (51-40), 4-2 | Three Rivers Stadium (29-15) | 50-40 | |
| » W: Burt Hooton (9-3) L: John Candelaria (6-9) S: Steve Howe (9) | First | -- |
| » Defeated Dodgers (51-41), 8-7 | Three Rivers Stadium (30-15) | 51-40 | |
| » W: Grant Jackson (8-2) L: Bobby Castillo (3-5) | First | -- |
| Tuesday, July 22 |
| » Defeated Padres (38-55), 4-3 | San Diego/Jack Murphy Stadium (3-1) | 52-40 | Won 2 |
| » W: Jim Bibby (12-1) L: Gary Lucas (3-6) S: Kent Tekulve (13) | First | -- |
| Wednesday, July 23 |
| » Lost to Padres (39-55), 3-2 | San Diego/Jack Murphy Stadium (3-2) | 52-41 | |
| » W: Rollie Fingers (8-7) L: Enrique Romo (5-4) | First | -- |
| Thursday, July 24 |
| » Defeated Padres (39-56), 7-1 | San Diego/Jack Murphy Stadium (4-2) | 53-41 | |
| » W: Bert Blyleven (5-7) L: Bob Shirley (6-7) | First | -- |
| Friday, July 25 |
| » Defeated Giants (47-49), 5-1 | Candlestick Park (3-1) | 54-41 | Won 2 |
| » W: John Candelaria (7-9) L: Bob Knepper (8-12) | First | -- |
| Saturday, July 26 |
| » Lost to Giants (48-49), 4-3 | Candlestick Park (3-2) | 54-42 | |
| » W: Greg Minton (3-3) L: Grant Jackson (8-3) | First | -- |
| Sunday, July 27 |
| » Defeated Giants (48-50), 6-4 | Candlestick Park (4-2) | 55-42 | |
| » W: Jim Bibby (13-1) L: Bill Bordley (2-2) S: Kent Tekulve (14) | First | -- |
| Monday, July 28 |
| » Defeated Dodgers (53-46), 6-4 | Dodger Stadium (1-3) | 56-42 | Won 2 |
| » W: Rick Rhoden (2-1) L: Bob Welch (9-6) S: Kent Tekulve (15) | First | -- |
| Tuesday, July 29 |
| » Lost to Dodgers (54-46), 10-2 | Dodger Stadium (1-4) | 56-43 | |
| » W: Burt Hooton (10-3) L: Bert Blyleven (5-8) | First | -- |
| Wednesday, July 30 |
| » Lost to Dodgers (55-46), 3-0 | Dodger Stadium (1-5) | 56-44 | Lost 2 |
| » W: Jerry Reuss (11-4) L: John Candelaria (7-10) | First | -- |
| Friday, August 1 |
| » Lost to Padres (45-57), 1-0 | Three Rivers Stadium (30-16) | 56-45 | Lost 3 |
| » W: Steve Mura (4-3) L: Jim Bibby (13-2) S: Rollie Fingers (13) | Second | 1 out |
| Sunday, August 3 |
| » Lost to Padres (46-57), 5-2 | Three Rivers Stadium (30-17) | 56-46 | Lost 4 |
| » W: John Curtis (4-7) L: Rick Rhoden (2-2) | Second | 2 out |
| » Lost to Padres (47-57), 4-1 | Three Rivers Stadium (30-18) | 56-47 | Lost 5 |
| » W: Bob Shirley (8-7) L: Don Robinson (3-5) S: Rollie Fingers (14) | Second | 2 out |
| Tuesday, August 5 |
| » Lost to Cubs (43-58), 11-3 | Wrigley Field (1-2) | 56-48 | Lost 6 |
| » W: Rick Reuschel (8-9) L: John Candelaria (7-11) | Second | 3 out |
| Wednesday, August 6 |
| » Defeated Cubs (43-59), 9-7 | Wrigley Field (2-2) | 57-48 | |
| » W: Kent Tekulve (7-5) L: Dick Tidrow (4-3) S: Enrique Romo (7) | Second | 2½ out |
| » Defeated Cubs (43-60), 2-0 | Wrigley Field (3-2) | 58-48 | Won 2 |
| » W: Bert Blyleven (6-8) L: Doug Capilla (2-5) S: Grant Jackson (6) | Second | 2½ out |
| Thursday, August 7 |
| » Defeated Cubs (43-61), 11-3 | Wrigley Field (4-2) | 59-48 | Won 3 |
| » W: Eddie Solomon (6-3) L: Willie Hernandez (1-9) | Second | 1½ out |
| Friday, August 8 |
| » Defeated Phillies (55-49), 6-5 | Three Rivers Stadium (31-18) | 60-48 | Won 4 |
| » W: Kent Tekulve (8-5) L: Tug McGraw (0-4) S: Enrique Romo (8) | Second | 1 out |
| Saturday, August 9 |
| » Defeated Phillies (55-50), 4-1 | Three Rivers Stadium (32-18) | 61-48 | Won 5 |
| » W: John Candelaria (8-11) L: Nino Espinosa (2-3) S: Kent Tekulve (16) | Second | ½ out |
| Sunday, August 10 |
| » Defeated Phillies (55-51), 7-1 | Three Rivers Stadium (33-18) | 62-48 | Won 6 |
| » W: Jim Bibby (14-2) L: Randy Lerch (3-13) | First | -- |
| » Defeated Phillies (55-52), 4-1 | Three Rivers Stadium (34-18) | 63-48 | Won 7 |
| » W: Don Robinson (4-5) L: Dan Larson (0-5) S: Kent Tekulve (17) | First | -- |
| Monday, August 11 |
| » Defeated Mets (54-57), 2-1 | Three Rivers Stadium (35-18) | 64-48 | Won 8 |
| » W: Eddie Solomon (7-3) L: Roy Lee Jackson (1-3) | First | -- |
| Tuesday, August 12 |
| » Lost to Mets (55-57), 3-1 | Three Rivers Stadium (35-19) | 64-49 | |
| » W: Ray Burris (6-6) L: Rick Rhoden (2-3) S: Neil Allen (21) | First | -- |
| Wednesday, August 13 |
| » Lost to Mets (56-57), 5-3 | Three Rivers Stadium (35-20) | 64-50 | Lost 2 |
| » W: Tom Hausman (5-3) L: John Candelaria (8-12) S: Jeff Reardon (4) | First | -- |
| Friday, August 15 |
| » Defeated Expos (64-51), 7-3 | Three Rivers Stadium (36-20) | 65-50 | |
| » W: Jim Bibby (15-2) L: Steve Rogers (11-8) S: Kent Tekulve (18) | First | -- |
| Saturday, August 16 |
| » Defeated Expos (64-52), 5-0 | Three Rivers Stadium (37-20) | 66-50 | Won 2 |
| » W: Bert Blyleven (7-8) L: Scott Sanderson (12-7) | First | -- |
| Sunday, August 17 |
| » Defeated Expos (64-53), 5-1 | Three Rivers Stadium (38-20) | 67-50 | Won 3 |
| » W: Rick Rhoden (3-3) L: Fred Norman (3-3) | First | -- |
| » Lost to Expos (65-53), 4-2 | Three Rivers Stadium (38-21) | 67-51 | |
| » W: Bill Gullickson (5-3) L: Don Robinson (4-6) S: Woodie Fryman (14) | First | -- |
| Tuesday, August 19 |
| » Lost to Astros (65-53), 5-2 | Astrodome (1-3) | 67-52 | Lost 2 |
| » W: Nolan Ryan (8-8) L: John Candelaria (8-13) S: Joe Sambito (12) | First | -- |
| Wednesday, August 20 |
| » Lost to Astros (66-53), 5-1 | Astrodome (1-4) | 67-53 | Lost 3 |
| » W: Vern Ruhle (7-2) L: Jim Bibby (15-3) S: Dave Smith (6) | First | -- |
| Thursday, August 21 |
| » Lost to Astros (67-53), 12-5 | Astrodome (1-5) | 67-54 | Lost 4 |
| » W: Joe Sambito (8-3) L: Bert Blyleven (7-9) | First | -- |
| Friday, August 22 |
| » Defeated Reds (66-56), 4-2 | Riverfront Stadium (3-1) | 68-54 | |
| » W: Don Robinson (5-6) L: Paul Moskau (8-5) S: Kent Tekulve (19) | First | -- |
| Saturday, August 23 |
| » Defeated Reds (66-57), 2-1 | Riverfront Stadium (4-1) | 69-54 | Won 2 |
| » W: Rick Rhoden (4-3) L: Frank Pastore (10-6) S: Grant Jackson (7) | First | -- |
| Sunday, August 24 |
| » Defeated Reds (66-58), 5-2 | Riverfront Stadium (5-1) | 70-54 | Won 3 |
| » W: John Candelaria (9-13) L: Mike LaCoss (7-10) | First | -- |
| Monday, August 25 |
| » Lost to Braves (61-63), 8-6 | Three Rivers Stadium (38-22) | 70-55 | |
| » W: Preston Hanna (1-0) L: Jim Bibby (15-4) S: Larry Bradford (4) | First | -- |
| » Major-league debuts: Gary Cooper (Braves) |
| Former Pirate Cliff Lee dies in Denver, CO at the age of 85. |
| Tuesday, August 26 |
| » Lost to Braves (62-63), 4-2 | Three Rivers Stadium (38-23) | 70-56 | Lost 2 |
| » W: Gene Garber (5-5) L: Kent Tekulve (8-6) | First | -- |
| Wednesday, August 27 |
| » Lost to Braves (63-63), 7-4 | Three Rivers Stadium (38-24) | 70-57 | Lost 3 |
| » W: Rick Matula (8-12) L: Don Robinson (5-7) S: Al Hrabosky (3) | First | -- |
| Thursday, August 28 |
| » Lost to Reds (68-59), 4-0 | Three Rivers Stadium (38-25) | 70-58 | Lost 4 |
| » W: Paul Moskau (9-5) L: Rick Rhoden (4-4) | Second | 1 out |
| Friday, August 29 |
| » Lost to Reds (69-59), 8-7 | Three Rivers Stadium (38-26) | 70-59 | Lost 5 |
| » W: Mario Soto (8-5) L: Kent Tekulve (8-7) S: Tom Hume (22) | First | -- |
| Saturday, August 30 |
| » Lost to Reds (70-59), 5-3 | Three Rivers Stadium (38-27) | 70-60 | Lost 6 |
| » W: Tom Seaver (6-7) L: Jim Bibby (15-5) | Second | 1 out |
| Sunday, August 31 |
| » Lost to Reds (71-59), 5-4 | Three Rivers Stadium (38-28) | 70-61 | Lost 7 |
| » W: Mike LaCoss (8-10) L: Bert Blyleven (7-10) S: Mario Soto (2) | First | -- |
| Monday, September 1 |
| » Lost to Astros (75-56), 10-4 | Three Rivers Stadium (38-29) | 70-62 | Lost 8 |
| » W: Dave Smith (5-5) L: Don Robinson (5-8) | Second | 2 out |
| » Defeated Astros (75-57), 7-5 | Three Rivers Stadium (39-29) | 71-62 | |
| » W: Rick Rhoden (5-4) L: Gordie Pladson (0-4) S: Grant Jackson (8) | Second | 2 out |
| » Major-league debuts: Tony Pena (Pirates) |
| Tuesday, September 2 |
| » Major-league debuts: Eddie Milner (Reds) |
| Wednesday, September 3 |
| » Defeated Astros (75-58), 10-4 | Three Rivers Stadium (40-29) | 72-62 | Won 2 |
| » W: John Candelaria (10-13) L: Joaquin Andujar (2-5) S: Enrique Romo (9) | Second | 1½ out |
| Thursday, September 4 |
| » Major-league debuts: Fred Breining (Giants) |
| Friday, September 5 |
| » Lost to Braves (69-65), 7-4 | Atlanta-Fulton County Stadium (0-4) | 72-63 | |
| » W: Rick Camp (5-4) L: Kent Tekulve (8-8) | Third | 1 out |
| Saturday, September 6 |
| » Lost to Braves (70-65), 3-2 | Atlanta-Fulton County Stadium (0-5) | 72-64 | Lost 2 |
| » W: Phil Niekro (13-14) L: Bert Blyleven (7-11) S: Gene Garber (7) | Third | 2 out |
| Sunday, September 7 |
| » Lost to Braves (71-65), 6-5 | Atlanta-Fulton County Stadium (0-6) | 72-65 | Lost 3 |
| » W: Larry Bradford (3-4) L: Kent Tekulve (8-9) S: Rick Camp (14) | Third | 2 out |
| Monday, September 8 |
| » Lost to Phillies (73-63), 6-2 | Veteran's Stadium (4-4) | 72-66 | Lost 4 |
| » W: Tug McGraw (1-4) L: Enrique Romo (5-5) | Third | 2½ out |
| Tuesday, September 9 |
| » Lost to Phillies (74-63), 5-4 | Veteran's Stadium (4-5) | 72-67 | Lost 5 |
| » W: Warren Brusstar (2-0) L: Mark Lee (0-1) | Third | 3½ out |
| Wednesday, September 10 |
| » Defeated Cardinals (62-76), 7-6 | Busch Stadium II (4-4) | 73-67 | |
| » W: Jim Bibby (16-5) L: Don Hood (4-6) S: Enrique Romo (10) | Third | 3½ out |
| Thursday, September 11 |
| » Defeated Cardinals (62-77), 2-1 | Busch Stadium II (5-4) | 74-67 | Won 2 |
| » W: Bert Blyleven (8-11) L: John Martin (1-2) | Third | 3½ out |
| Friday, September 12 |
| » Lost to Expos (78-63), 1-0 | Stade Olympique (4-3) | 74-68 | |
| » W: Scott Sanderson (15-8) L: Rick Rhoden (5-5) | Third | 4½ out |
| Saturday, September 13 |
| » Defeated Expos (78-64), 4-0 | Stade Olympique (5-3) | 75-68 | |
| » W: Don Robinson (6-8) L: Steve Rogers (14-11) | Third | 3½ out |
| Sunday, September 14 |
| » Lost to Expos (79-64), 4-0 | Stade Olympique (5-4) | 75-69 | |
| » W: Bill Gullickson (9-4) L: John Candelaria (10-14) | Third | 4½ out |
| Monday, September 15 |
| » Major-league debuts: Andy Rincon (Cardinals) |
| Tuesday, September 16 |
| » Defeated Phillies (78-66), 3-2 | Three Rivers Stadium (41-29) | 76-69 | |
| » W: Jim Bibby (17-5) L: Dick Ruthven (15-10) S: Kent Tekulve (20) | Third | 5 out |
| Wednesday, September 17 |
| » Lost to Phillies (79-66), 5-4 | Three Rivers Stadium (41-30) | 76-70 | |
| » W: Tug McGraw (2-4) L: Kent Tekulve (8-10) S: Sparky Lyle (9) | Third | 5 out |
| Friday, September 19 |
| » Defeated Mets (62-85), 4-3 | Three Rivers Stadium (42-30) | 77-70 | |
| » W: Rick Rhoden (6-5) L: Ed Lynch (1-1) | Third | 4 out |
| Saturday, September 20 |
| » Lost to Mets (63-85), 9-6 | Three Rivers Stadium (42-31) | 77-71 | |
| » W: Neil Allen (7-8) L: Kent Tekulve (8-11) S: Dyar Miller (1) | Third | 5 out |
| » Major-league debuts: Scott Holman (Mets) |
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