| Thursday, April 10 |
| » Defeated Giants (0-1), 6-4 | San Diego/Jack Murphy Stadium (1-0) | 1-0 | |
| » W: Randy Jones (1-0) L: Bob Knepper (0-1) S: Bob Shirley (1) | First | -- |
| Friday, April 11 |
| » Defeated Giants (0-2), 5-3 | San Diego/Jack Murphy Stadium (2-0) | 2-0 | Won 2 |
| » W: Rollie Fingers (1-0) L: Gary Lavelle (0-1) | First | -- |
| Saturday, April 12 |
| » Defeated Giants (0-3), 4-2 | San Diego/Jack Murphy Stadium (3-0) | 3-0 | Won 3 |
| » W: John Curtis (1-0) L: John Montefusco (0-1) S: Bob Shirley (2) | First | -- |
| Sunday, April 13 |
| » Lost to Giants (1-3), 3-1 | San Diego/Jack Murphy Stadium (3-1) | 3-1 | |
| » W: Vida Blue (1-0) L: Eric Rasmussen (0-1) S: Gary Lavelle (1) | Second | 1 out |
| Monday, April 14 |
| » Defeated Dodgers (1-4), 2-1 | San Diego/Jack Murphy Stadium (4-1) | 4-1 | |
| » W: Rollie Fingers (2-0) L: Bobby Castillo (0-1) | Second | 1 out |
| Tuesday, April 15 |
| » Defeated Dodgers (1-5), 9-5 | San Diego/Jack Murphy Stadium (5-1) | 5-1 | Won 2 |
| » W: Rick Wise (1-0) L: Rick Sutcliffe (0-1) S: Steve Mura (1) | Second | 1 out |
| Wednesday, April 16 |
| » Lost to Dodgers (2-5), 10-4 | San Diego/Jack Murphy Stadium (5-2) | 5-2 | |
| » W: Burt Hooton (1-1) L: John Curtis (1-1) | Third | 2 out |
| » Major-league debuts: Gary Lucas (Padres) |
| Thursday, April 17 |
| » Lost to Giants (2-6), 7-3 | Candlestick Park (0-1) | 5-3 | Lost 2 |
| » W: Vida Blue (2-0) L: Eric Rasmussen (0-2) | Third | 3 out |
| Friday, April 18 |
| » Lost to Giants (3-6), 5-2 | Candlestick Park (0-2) | 5-4 | Lost 3 |
| » W: Bob Knepper (1-1) L: Randy Jones (1-1) | Third | 3 out |
| Saturday, April 19 |
| » Defeated Giants (3-7), 3-0 | Candlestick Park (1-2) | 6-4 | |
| » W: Gary Lucas (1-0) L: Ed Whitson (0-2) S: Rollie Fingers (1) | Third | 3 out |
| Sunday, April 20 |
| » Lost to Giants (4-7), 5-1 | Candlestick Park (1-3) | 6-5 | |
| » W: John Montefusco (1-2) L: Rick Wise (1-1) | Third | 4 out |
| Tuesday, April 22 |
| » Lost to Braves (2-9), 3-2 | Atlanta-Fulton County Stadium (0-1) | 6-6 | Lost 2 |
| » W: Al Hrabosky (1-1) L: Bob Shirley (0-1) | Third | 4½ out |
| Wednesday, April 23 |
| » Lost to Braves (3-9), 2-1 | Atlanta-Fulton County Stadium (0-2) | 6-7 | Lost 3 |
| » W: Rick Matula (2-0) L: Randy Jones (1-2) S: Al Hrabosky (1) | Fourth | 5½ out |
| Thursday, April 24 |
| » Lost to Braves (4-9), 8-7 | Atlanta-Fulton County Stadium (0-3) | 6-8 | Lost 4 |
| » W: Gene Garber (1-1) L: Rollie Fingers (2-1) | Fourth | 6 out |
| Friday, April 25 |
| » Lost to Dodgers (9-7), 6-3 | Dodger Stadium (0-1) | 6-9 | Lost 5 |
| » W: Bobby Castillo (1-1) L: Dennis Kinney (0-1) S: Steve Howe (2) | Fourth | 6 out |
| Saturday, April 26 |
| » Lost to Dodgers (10-7), 4-3 | Dodger Stadium (0-2) | 6-10 | Lost 6 |
| » W: Joe Beckwith (1-0) L: Rollie Fingers (2-2) | Fourth | 6 out |
| Sunday, April 27 |
| » Lost to Dodgers (11-7), 3-1 | Dodger Stadium (0-3) | 6-11 | Lost 7 |
| » W: Don Sutton (2-0) L: John Curtis (1-2) S: Charlie Hough (1) | Fifth | 7 out |
| Wednesday, April 30 |
| » Defeated Braves (6-11), 2-1 | San Diego/Jack Murphy Stadium (6-2) | 7-11 | |
| » W: Eric Rasmussen (1-2) L: Rick Matula (2-1) S: Bob Shirley (3) | Fourth | 6 out |
| Thursday, May 1 |
| » Defeated Braves (6-12), 4-3 | San Diego/Jack Murphy Stadium (7-2) | 8-11 | Won 2 |
| » W: Bob Shirley (1-1) L: Rick Camp (0-1) | Third | 6 out |
| Friday, May 2 |
| » Defeated Mets (6-12), 1-0 | Shea Stadium (1-0) | 9-11 | Won 3 |
| » W: Rick Wise (2-1) L: Ray Burris (2-2) S: Steve Mura (2) | Third | 5 out |
| Saturday, May 3 |
| » Defeated Mets (6-13), 2-1 | Shea Stadium (2-0) | 10-11 | Won 4 |
| » W: Gary Lucas (2-0) L: Craig Swan (1-2) S: Rollie Fingers (2) | Third | 5 out |
| Sunday, May 4 |
| » Defeated Mets (6-14), 4-3 | Shea Stadium (3-0) | 11-11 | Won 5 |
| » W: John Curtis (2-2) L: Jeff Reardon (0-1) S: Bob Shirley (4) | Fourth | 5½ out |
| » Lost to Mets (7-14), 6-2 | Shea Stadium (3-1) | 11-12 | |
| » W: Ed Glynn (1-1) L: Eric Rasmussen (1-3) S: Neil Allen (5) | Fourth | 5½ out |
| Tuesday, May 6 |
| » Defeated Cubs (11-9), 4-0 | Wrigley Field (1-0) | 12-12 | |
| » W: Randy Jones (2-2) L: Willie Hernandez (1-2) | Fourth | 5 out |
| Wednesday, May 7 |
| » Lost to Cubs (12-9), 7-4 | Wrigley Field (1-1) | 12-13 | |
| » W: Mike Krukow (3-1) L: Rick Wise (2-2) S: Bruce Sutter (8) | Fourth | 5 out |
| Thursday, May 8 |
| » Defeated Cubs (12-10), 9-6 | Wrigley Field (2-1) | 13-13 | |
| » W: Bob Shirley (2-1) L: Bruce Sutter (2-2) S: Rollie Fingers (3) | Fourth | 4½ out |
| Friday, May 9 |
| » Lost to Pirates (16-7), 4-3 | San Diego/Jack Murphy Stadium (7-3) | 13-14 | |
| » W: Kent Tekulve (5-0) L: Rollie Fingers (2-3) | Fourth | 4½ out |
| Saturday, May 10 |
| » Lost to Pirates (17-7), 9-5 | San Diego/Jack Murphy Stadium (7-4) | 13-15 | Lost 2 |
| » W: Don Robinson (1-0) L: Eric Rasmussen (1-4) S: Enrique Romo (1) | Fourth | 5½ out |
| Sunday, May 11 |
| » Defeated Pirates (17-8), 5-0 | San Diego/Jack Murphy Stadium (8-4) | 14-15 | |
| » W: Randy Jones (3-2) L: John Candelaria (2-2) | Fourth | 4½ out |
| Tuesday, May 13 |
| » Defeated Cardinals (13-15), 3-2 | San Diego/Jack Murphy Stadium (9-4) | 15-15 | Won 2 |
| » W: Rollie Fingers (3-3) L: Jim Kaat (0-2) | Fourth | 4½ out |
| Wednesday, May 14 |
| » Lost to Cardinals (14-15), 2-1 | San Diego/Jack Murphy Stadium (9-5) | 15-16 | |
| » W: Roy Thomas (1-0) L: Gary Lucas (2-1) S: Mark Littell (2) | Fourth | 4½ out |
| Thursday, May 15 |
| » Defeated Cardinals (14-16), 2-1 | San Diego/Jack Murphy Stadium (10-5) | 16-16 | |
| » W: John Curtis (3-2) L: Pete Vuckovich (5-3) S: Rollie Fingers (4) | Fourth | 4 out |
| Friday, May 16 |
| » Defeated Cubs (14-15), 3-0 | San Diego/Jack Murphy Stadium (11-5) | 17-16 | Won 2 |
| » W: Randy Jones (4-2) L: Mike Krukow (3-3) | Fourth | 3 out |
| Saturday, May 17 |
| » Lost to Cubs (15-15), 2-1 | San Diego/Jack Murphy Stadium (11-6) | 17-17 | |
| » W: Rick Reuschel (3-3) L: Eric Rasmussen (1-5) S: Bruce Sutter (10) | Fourth | 3½ out |
| Sunday, May 18 |
| » Defeated Cubs (15-16), 4-3 | San Diego/Jack Murphy Stadium (12-6) | 18-17 | |
| » W: Rollie Fingers (4-3) L: Bruce Sutter (2-3) | Fourth | 3½ out |
| Wednesday, May 21 |
| » Lost to Pirates (20-12), 4-3 | Three Rivers Stadium (0-1) | 18-18 | |
| » W: Enrique Romo (2-0) L: Rollie Fingers (4-4) | Fourth | 6 out |
| » Lost to Pirates (21-12), 3-2 | Three Rivers Stadium (0-2) | 18-19 | Lost 2 |
| » W: Grant Jackson (3-1) L: John Curtis (3-3) S: Kent Tekulve (5) | Fourth | 6 out |
| Thursday, May 22 |
| » Defeated Pirates (21-13), 6-4 | Three Rivers Stadium (1-2) | 19-19 | |
| » W: Bob Shirley (3-1) L: Kent Tekulve (5-2) S: Rollie Fingers (5) | Fourth | 5½ out |
| Friday, May 23 |
| » Defeated Cardinals (14-23), 2-0 | Busch Stadium II (1-0) | 20-19 | Won 2 |
| » W: Bob Shirley (4-1) L: Jim Kaat (0-3) | Fourth | 4½ out |
| Saturday, May 24 |
| » Defeated Cardinals (14-24), 8-4 | Busch Stadium II (2-0) | 21-19 | Won 3 |
| » W: Dennis Kinney (1-1) L: Donnie Moore (1-1) | Fourth | 4½ out |
| Sunday, May 25 |
| » Defeated Cardinals (14-25), 11-5 | Busch Stadium II (3-0) | 22-19 | Won 4 |
| » W: Rollie Fingers (5-4) L: Roy Thomas (1-2) S: John D'Acquisto (1) | Fourth | 3½ out |
| Monday, May 26 |
| » Lost to Astros (22-18), 4-1 | Astrodome (0-1) | 22-20 | |
| » W: J.R. Richard (5-3) L: John Curtis (3-4) S: Joe Sambito (4) | Fourth | 4 out |
| Tuesday, May 27 |
| » Lost to Astros (23-18), 4-3 | Astrodome (0-2) | 22-21 | Lost 2 |
| » W: Frank LaCorte (3-0) L: Rollie Fingers (5-5) | Fourth | 4 out |
| Wednesday, May 28 |
| » Lost to Astros (24-18), 1-0 | Astrodome (0-3) | 22-22 | Lost 3 |
| » W: Nolan Ryan (3-4) L: Rick Wise (2-3) | Fourth | 4½ out |
| Thursday, May 29 |
| » Lost to Reds (25-19), 5-3 | San Diego/Jack Murphy Stadium (12-7) | 22-23 | Lost 4 |
| » W: Frank Pastore (6-2) L: Randy Jones (4-3) S: Tom Hume (6) | Fourth | 5½ out |
| Friday, May 30 |
| » Lost to Reds (26-19), 5-3 | San Diego/Jack Murphy Stadium (12-8) | 22-24 | Lost 5 |
| » W: Charlie Leibrandt (4-3) L: Steve Mura (0-1) S: Doug Bair (5) | Fourth | 6½ out |
| Saturday, May 31 |
| » Defeated Reds (26-20), 7-5 | San Diego/Jack Murphy Stadium (13-8) | 23-24 | |
| » W: Bob Shirley (5-1) L: Tom Hume (3-5) S: Rollie Fingers (6) | Fourth | 5½ out |
| Sunday, June 1 |
| » Lost to Reds (27-20), 7-6 | San Diego/Jack Murphy Stadium (13-9) | 23-25 | |
| » W: Sheldon Burnside (1-0) L: Gary Lucas (2-2) S: Tom Hume (7) | Fourth | 5½ out |
| Monday, June 2 |
| » Defeated Astros (25-21), 3-0 | San Diego/Jack Murphy Stadium (14-9) | 24-25 | |
| » W: Rick Wise (3-3) L: Nolan Ryan (3-5) S: Eric Rasmussen (1) | Fourth | 5½ out |
| Tuesday, June 3 |
| » Lost to Astros (26-21), 3-2 | San Diego/Jack Murphy Stadium (14-10) | 24-26 | |
| » W: Vern Ruhle (2-1) L: Randy Jones (4-4) S: Frank LaCorte (5) | Fourth | 6½ out |
| Wednesday, June 4 |
| » Lost to Astros (27-21), 4-3 | San Diego/Jack Murphy Stadium (14-11) | 24-27 | Lost 2 |
| » W: Ken Forsch (6-4) L: Rollie Fingers (5-6) S: Joe Sambito (5) | Fourth | 6½ out |
| Friday, June 6 |
| » Lost to Reds (29-22), 4-2 | Riverfront Stadium (0-1) | 24-28 | Lost 3 |
| » W: Frank Pastore (7-2) L: John D'Acquisto (0-1) S: Tom Hume (9) | Fourth | 7½ out |
| Saturday, June 7 |
| » Defeated Reds (29-23), 6-1 | Riverfront Stadium (1-1) | 25-28 | |
| » W: Gary Lucas (3-2) L: Mike LaCoss (4-5) S: Rollie Fingers (7) | Fourth | 6½ out |
| Sunday, June 8 |
| » Lost to Reds (30-23), 1-0 | Riverfront Stadium (1-2) | 25-29 | |
| » W: Charlie Leibrandt (5-3) L: Randy Jones (4-5) | Fourth | 7½ out |
| Monday, June 9 |
| » Tied Reds, 6-6 | Riverfront Stadium (1-2) | 25-29 | |
| » Starters: Steve Mura vs Paul Moskau | Fourth | 7½ out |
| Tuesday, June 10 |
| » Lost to Expos (30-20), 8-4 | Stade Olympique (0-1) | 25-30 | Lost 2 |
| » W: Stan Bahnsen (5-1) L: Eric Rasmussen (1-6) S: Elias Sosa (4) | Fourth | 8 out |
| Wednesday, June 11 |
| » Lost to Expos (31-20), 7-6 | Stade Olympique (0-2) | 25-31 | Lost 3 |
| » W: Elias Sosa (4-2) L: Bob Shirley (5-2) | Fourth | 9 out |
| Thursday, June 12 |
| » Lost to Expos (32-20), 9-1 | Stade Olympique (0-3) | 25-32 | Lost 4 |
| » W: Charlie Lea (1-0) L: Gary Lucas (3-3) | Fourth | 9½ out |
| » Major-league debuts: Charlie Lea (Expos) |
| Friday, June 13 |
| » Lost to Phillies (28-24), 9-6 | Veteran's Stadium (0-1) | 25-33 | Lost 5 |
| » W: Dick Ruthven (6-5) L: Randy Jones (4-6) | Third | 9½ out |
| Saturday, June 14 |
| » Lost to Phillies (29-24), 3-1 | Veteran's Stadium (0-2) | 25-34 | Lost 6 |
| » W: Steve Carlton (11-2) L: Steve Mura (0-2) S: Tug McGraw (5) | Fourth | 10½ out |
| Sunday, June 15 |
| » Lost to Phillies (30-24), 8-5 | Veteran's Stadium (0-3) | 25-35 | Lost 7 |
| » W: Bob Walk (2-0) L: Rick Wise (3-4) S: Lerrin LaGrow (1) | Fifth | 10½ out |
| Monday, June 16 |
| » Defeated Mets (27-30), 3-2 | San Diego/Jack Murphy Stadium (15-11) | 26-35 | |
| » W: Rollie Fingers (6-6) L: Jeff Reardon (4-3) S: Bob Shirley (5) | Fifth | 10½ out |
| Tuesday, June 17 |
| » Defeated Mets (27-31), 2-1 | San Diego/Jack Murphy Stadium (16-11) | 27-35 | Won 2 |
| » W: Rollie Fingers (7-6) L: Tom Hausman (2-2) | Fourth | 10½ out |
| Wednesday, June 18 |
| » Lost to Phillies (33-24), 5-1 | San Diego/Jack Murphy Stadium (16-12) | 27-36 | |
| » W: Steve Carlton (12-2) L: Bob Shirley (5-3) | Sixth | 11½ out |
| Thursday, June 19 |
| » Defeated Phillies (33-25), 4-3 | San Diego/Jack Murphy Stadium (17-12) | 28-36 | |
| » W: Dennis Kinney (2-1) L: Kevin Saucier (3-1) S: Rollie Fingers (8) | Sixth | 11½ out |
| Friday, June 20 |
| » Defeated Expos (34-26), 4-2 | San Diego/Jack Murphy Stadium (18-12) | 29-36 | Won 2 |
| » W: Steve Mura (1-2) L: Scott Sanderson (6-4) S: Bob Shirley (6) | Fifth | 11½ out |
| Saturday, June 21 |
| » Lost to Expos (35-26), 7-4 | San Diego/Jack Murphy Stadium (18-13) | 29-37 | |
| » W: Charlie Lea (2-1) L: John Curtis (3-5) S: Elias Sosa (5) | Sixth | 12½ out |
| Sunday, June 22 |
| » Lost to Expos (36-26), 2-0 | San Diego/Jack Murphy Stadium (18-14) | 29-38 | Lost 2 |
| » W: Steve Rogers (9-5) L: Gary Lucas (3-4) | Sixth | 12½ out |
| Tuesday, June 24 |
| » Defeated Giants (30-37), 5-3 | San Diego/Jack Murphy Stadium (19-14) | 30-38 | |
| » W: John D'Acquisto (1-1) L: Bob Knepper (5-9) | Fifth | 12 out |
| Wednesday, June 25 |
| » Defeated Giants (30-38), 7-3 | San Diego/Jack Murphy Stadium (20-14) | 31-38 | Won 2 |
| » W: Juan Eichelberger (1-0) L: Allen Ripley (2-2) S: Rollie Fingers (9) | Fourth | 11 out |
| Thursday, June 26 |
| » Lost to Giants (31-38), 2-1 | San Diego/Jack Murphy Stadium (20-15) | 31-39 | |
| » W: Ed Whitson (6-7) L: Steve Mura (1-3) S: Greg Minton (5) | Fifth | 11½ out |
| Friday, June 27 |
| » Lost to Braves (29-38), 5-3 | San Diego/Jack Murphy Stadium (20-16) | 31-40 | Lost 2 |
| » W: Rick Camp (2-2) L: John Curtis (3-6) S: Gene Garber (5) | Fifth | 12½ out |
| Saturday, June 28 |
| » Lost to Braves (30-38), 5-4 | San Diego/Jack Murphy Stadium (20-17) | 31-41 | Lost 3 |
| » W: Larry Bradford (2-4) L: Bob Shirley (5-4) S: Gene Garber (6) | Fifth | 12 out |
| » Defeated Braves (30-39), 3-2 | San Diego/Jack Murphy Stadium (21-17) | 32-41 | |
| » W: John D'Acquisto (2-1) L: Rick Camp (2-3) | Fifth | 12 out |
| Sunday, June 29 |
| » Lost to Braves (31-39), 4-2 | San Diego/Jack Murphy Stadium (21-18) | 32-42 | |
| » W: Larry McWilliams (4-5) L: Eric Rasmussen (1-7) | Sixth | 13 out |
| Monday, June 30 |
| » Defeated Dodgers (42-32), 4-3 | Dodger Stadium (1-3) | 33-42 | |
| » W: Juan Eichelberger (2-0) L: Bob Welch (8-3) S: Bob Shirley (7) | Sixth | 12 out |
| Tuesday, July 1 |
| » Defeated Dodgers (42-33), 4-1 | Dodger Stadium (2-3) | 34-42 | Won 2 |
| » W: Steve Mura (2-3) L: Jerry Reuss (9-2) S: Rollie Fingers (10) | Sixth | 11 out |
| Wednesday, July 2 |
| » Lost to Dodgers (43-33), 10-7 | Dodger Stadium (2-4) | 34-43 | |
| » W: Rick Sutcliffe (3-5) L: Dennis Blair (0-1) | Sixth | 11 out |
| Thursday, July 3 |
| » Lost to Dodgers (44-33), 5-4 | Dodger Stadium (2-5) | 34-44 | Lost 2 |
| » W: Bobby Castillo (3-4) L: Bob Shirley (5-5) | Sixth | 12 out |
| Friday, July 4 |
| » Lost to Braves (35-40), 9-0 | Atlanta-Fulton County Stadium (0-4) | 34-45 | Lost 3 |
| » W: Larry McWilliams (5-5) L: Eric Rasmussen (1-8) | Sixth | 12 out |
| Saturday, July 5 |
| » Lost to Braves (36-40), 3-2 | Atlanta-Fulton County Stadium (0-5) | 34-46 | Lost 4 |
| » W: Rick Matula (6-6) L: Rollie Fingers (7-7) | Sixth | 12½ out |
| Sunday, July 6 |
| » Lost to Braves (37-40), 6-5 | Atlanta-Fulton County Stadium (0-6) | 34-47 | Lost 5 |
| » W: Doyle Alexander (7-3) L: Bob Shirley (5-6) S: Phil Niekro (1) | Sixth | 12½ out |
| Thursday, July 10 |
| » Lost to Giants (38-43), 9-2 | Candlestick Park (1-4) | 34-48 | Lost 6 |
| » W: Bob Knepper (8-9) L: Randy Jones (4-7) | Sixth | 13½ out |
| » Major-league debuts: Joe Pettini (Giants) |
| Friday, July 11 |
| » Lost to Giants (39-43), 7-3 | Candlestick Park (1-5) | 34-49 | Lost 7 |
| » W: Ed Whitson (8-8) L: John Curtis (3-7) | Sixth | 14½ out |
| Saturday, July 12 |
| » Defeated Dodgers (48-35), 3-2 | San Diego/Jack Murphy Stadium (22-18) | 35-49 | |
| » W: Eric Rasmussen (2-8) L: Joe Beckwith (3-2) | Sixth | 13½ out |
| Sunday, July 13 |
| » Defeated Dodgers (48-36), 4-3 | San Diego/Jack Murphy Stadium (23-18) | 36-49 | Won 2 |
| » W: Dennis Kinney (3-1) L: Joe Beckwith (3-3) | Sixth | 13 out |
| Monday, July 14 |
| » Defeated Dodgers (48-37), 6-3 | San Diego/Jack Murphy Stadium (24-18) | 37-49 | Won 3 |
| » W: Steve Mura (3-3) L: Rick Sutcliffe (3-6) | Sixth | 12 out |
| Tuesday, July 15 |
| » Lost to Cardinals (37-49), 5-3 | Busch Stadium II (3-1) | 37-50 | |
| » W: Bob Forsch (6-6) L: Randy Jones (4-8) S: John Littlefield (4) | Sixth | 13 out |
| Wednesday, July 16 |
| » Lost to Cardinals (38-49), 3-0 | Busch Stadium II (3-2) | 37-51 | Lost 2 |
| » W: Pete Vuckovich (8-6) L: Gary Lucas (3-5) | Sixth | 13 out |
| Thursday, July 17 |
| » Lost to Cardinals (39-49), 15-3 | Busch Stadium II (3-3) | 37-52 | Lost 3 |
| » W: Jim Kaat (4-6) L: Rick Wise (3-5) | Sixth | 13½ out |
| Friday, July 18 |
| » Defeated Cubs (35-50), 2-1 | Wrigley Field (3-1) | 38-52 | |
| » W: Bob Shirley (6-6) L: Doug Capilla (2-2) S: Rollie Fingers (11) | Sixth | 12½ out |
| Saturday, July 19 |
| » Lost to Cubs (36-50), 8-7 | Wrigley Field (3-2) | 38-53 | |
| » W: Bill Caudill (1-1) L: Dennis Kinney (3-2) | Fifth | 12½ out |
| Sunday, July 20 |
| » Lost to Cubs (37-50), 6-0 | Wrigley Field (3-3) | 38-54 | Lost 2 |
| » W: Lynn McGlothen (7-7) L: Randy Jones (4-9) | Sixth | 13½ out |
| » Major-league debuts: Jim Tracy (Cubs) |
| Tuesday, July 22 |
| » Lost to Pirates (52-40), 4-3 | San Diego/Jack Murphy Stadium (24-19) | 38-55 | Lost 3 |
| » W: Jim Bibby (12-1) L: Gary Lucas (3-6) S: Kent Tekulve (13) | Sixth | 15 out |
| Wednesday, July 23 |
| » Defeated Pirates (52-41), 3-2 | San Diego/Jack Murphy Stadium (25-19) | 39-55 | |
| » W: Rollie Fingers (8-7) L: Enrique Romo (5-4) | Sixth | 14 out |
| Thursday, July 24 |
| » Lost to Pirates (53-41), 7-1 | San Diego/Jack Murphy Stadium (25-20) | 39-56 | |
| » W: Bert Blyleven (5-7) L: Bob Shirley (6-7) | Sixth | 14½ out |
| Friday, July 25 |
| » Lost to Cardinals (44-51), 3-2 | San Diego/Jack Murphy Stadium (25-21) | 39-57 | Lost 2 |
| » W: Bob Sykes (4-8) L: Dennis Kinney (3-3) S: John Littlefield (7) | Sixth | 15½ out |
| Saturday, July 26 |
| » Defeated Cardinals (44-52), 4-3 | San Diego/Jack Murphy Stadium (26-21) | 40-57 | |
| » W: Dennis Kinney (4-3) L: Don Hood (2-4) | Sixth | 14½ out |
| Sunday, July 27 |
| » Defeated Cardinals (44-53), 5-2 | San Diego/Jack Murphy Stadium (27-21) | 41-57 | Won 2 |
| » W: Gary Lucas (4-6) L: Pete Vuckovich (9-7) S: Rollie Fingers (12) | Sixth | 14½ out |
| Monday, July 28 |
| » Defeated Cubs (39-55), 4-2 | San Diego/Jack Murphy Stadium (28-21) | 42-57 | Won 3 |
| » W: Rollie Fingers (9-7) L: George Riley (0-1) | Sixth | 14½ out |
| Tuesday, July 29 |
| » Defeated Cubs (39-56), 3-1 | San Diego/Jack Murphy Stadium (29-21) | 43-57 | Won 4 |
| » W: Randy Jones (5-9) L: Doug Capilla (2-4) | Sixth | 13½ out |
| Wednesday, July 30 |
| » Defeated Cubs (39-57), 5-2 | San Diego/Jack Murphy Stadium (30-21) | 44-57 | Won 5 |
| » W: Bob Shirley (7-7) L: Bruce Sutter (3-6) | Sixth | 12½ out |
| Friday, August 1 |
| » Defeated Pirates (56-45), 1-0 | Three Rivers Stadium (2-2) | 45-57 | Won 6 |
| » W: Steve Mura (4-3) L: Jim Bibby (13-2) S: Rollie Fingers (13) | Sixth | 11½ out |
| Sunday, August 3 |
| » Defeated Pirates (56-46), 5-2 | Three Rivers Stadium (3-2) | 46-57 | Won 7 |
| » W: John Curtis (4-7) L: Rick Rhoden (2-2) | Fifth | 10½ out |
| » Defeated Pirates (56-47), 4-1 | Three Rivers Stadium (4-2) | 47-57 | Won 8 |
| » W: Bob Shirley (8-7) L: Don Robinson (3-5) S: Rollie Fingers (14) | Fifth | 10½ out |
| Monday, August 4 |
| » Lost to Reds (55-51), 7-1 | Riverfront Stadium (1-3) | 47-58 | |
| » W: Tom Seaver (4-5) L: Randy Jones (5-10) S: Tom Hume (19) | Fifth | 12 out |
| » Lost to Reds (56-51), 11-2 | Riverfront Stadium (1-4) | 47-59 | Lost 2 |
| » W: Mario Soto (5-5) L: Dennis Kinney (4-4) | Fifth | 12 out |
| Tuesday, August 5 |
| » Lost to Reds (57-51), 9-2 | Riverfront Stadium (1-5) | 47-60 | Lost 3 |
| » W: Paul Moskau (8-3) L: Gary Lucas (4-7) | Sixth | 12 out |
| Wednesday, August 6 |
| » Lost to Reds (58-51), 4-3 | Riverfront Stadium (1-6) | 47-61 | Lost 4 |
| » W: Tom Hume (5-7) L: John D'Acquisto (2-2) | Sixth | 13 out |
| Thursday, August 7 |
| » Defeated Astros (59-48), 5-1 | Astrodome (1-3) | 48-61 | |
| » W: Bob Shirley (9-7) L: Joe Niekro (11-10) | Sixth | 12 out |
| Friday, August 8 |
| » Defeated Astros (59-49), 5-3 | Astrodome (2-3) | 49-61 | Won 2 |
| » W: Juan Eichelberger (3-0) L: Joe Sambito (7-2) S: Rollie Fingers (15) | Sixth | 11 out |
| Saturday, August 9 |
| » Lost to Astros (60-49), 9-5 | Astrodome (2-4) | 49-62 | |
| » W: Dave Smith (2-4) L: John D'Acquisto (2-3) | Sixth | 12 out |
| Sunday, August 10 |
| » Defeated Astros (60-50), 3-2 | Astrodome (3-4) | 50-62 | |
| » W: Rick Wise (4-5) L: Joe Sambito (7-3) | Sixth | 11½ out |
| Monday, August 11 |
| » Lost to Reds (60-53), 1-0 | San Diego/Jack Murphy Stadium (30-22) | 50-63 | |
| » W: Charlie Leibrandt (10-7) L: Steve Mura (4-4) S: Tom Hume (20) | Sixth | 11½ out |
| Tuesday, August 12 |
| » Lost to Reds (61-53), 3-2 | San Diego/Jack Murphy Stadium (30-23) | 50-64 | Lost 2 |
| » W: Joe Price (3-2) L: Randy Jones (5-11) | Sixth | 11½ out |
| » Major-league debuts: Mike Armstrong (Padres) |
| Wednesday, August 13 |
| » Lost to Reds (62-53), 4-3 | San Diego/Jack Murphy Stadium (30-24) | 50-65 | Lost 3 |
| » W: Mario Soto (6-5) L: Bob Shirley (9-8) | Sixth | 12 out |
| Thursday, August 14 |
| » Lost to Astros (61-53), 2-1 | San Diego/Jack Murphy Stadium (30-25) | 50-66 | Lost 4 |
| » W: Nolan Ryan (7-8) L: John Curtis (4-8) | Fifth | 12½ out |
| Friday, August 15 |
| » Lost to Astros (62-53), 3-1 | San Diego/Jack Murphy Stadium (30-26) | 50-67 | Lost 5 |
| » W: Dave Smith (3-5) L: Eric Rasmussen (2-9) | Fifth | 13 out |
| » Major-league debuts: Luis Salazar (Padres) |
| Sunday, August 17 |
| » Lost to Astros (63-53), 5-0 | San Diego/Jack Murphy Stadium (30-27) | 50-68 | Lost 6 |
| » W: Ken Forsch (10-10) L: Randy Jones (5-12) | Sixth | 15 out |
| » Lost to Astros (64-53), 9-2 | San Diego/Jack Murphy Stadium (30-28) | 50-69 | Lost 7 |
| » W: Joe Niekro (12-11) L: Steve Mura (4-5) | Sixth | 15 out |
| Tuesday, August 19 |
| » Lost to Phillies (63-53), 7-4 | Veteran's Stadium (0-4) | 50-70 | Lost 8 |
| » W: Dick Ruthven (11-8) L: Bob Shirley (9-9) S: Tug McGraw (13) | Sixth | 16 out |
| Wednesday, August 20 |
| » Defeated Phillies (63-54), 7-5 | Veteran's Stadium (1-4) | 51-70 | |
| » W: John Curtis (5-8) L: Nino Espinosa (3-4) S: Rollie Fingers (16) | Sixth | 16 out |
| Thursday, August 21 |
| » Lost to Phillies (64-54), 9-8 | Veteran's Stadium (1-5) | 51-71 | |
| » W: Kevin Saucier (6-3) L: Dennis Kinney (4-5) | Sixth | 17 out |
| Friday, August 22 |
| » Lost to Expos (66-56), 6-2 | Stade Olympique (0-4) | 51-72 | Lost 2 |
| » W: Fred Norman (4-3) L: Randy Jones (5-13) | Sixth | 18 out |
| Saturday, August 23 |
| » Lost to Expos (67-56), 2-0 | Stade Olympique (0-5) | 51-73 | Lost 3 |
| » W: Bill Gullickson (6-3) L: Steve Mura (4-6) S: John D'Acquisto (2) | Sixth | 19 out |
| Sunday, August 24 |
| » Lost to Expos (68-56), 12-9 | Stade Olympique (0-6) | 51-74 | Lost 4 |
| » W: Elias Sosa (8-5) L: Rollie Fingers (9-8) S: John D'Acquisto (3) | Sixth | 20 out |
| Tuesday, August 26 |
| » Defeated Mets (58-67), 8-6 | Shea Stadium (4-1) | 52-74 | |
| » W: Eric Rasmussen (3-9) L: Pete Falcone (6-8) S: Dennis Kinney (1) | Fifth | 19½ out |
| Wednesday, August 27 |
| » Defeated Mets (58-68), 4-1 | Shea Stadium (5-1) | 53-74 | Won 2 |
| » W: Rick Wise (5-5) L: Ray Burris (7-8) S: Rollie Fingers (17) | Fifth | 18½ out |
| Friday, August 29 |
| » Lost to Phillies (67-58), 3-2 | San Diego/Jack Murphy Stadium (30-29) | 53-75 | |
| » W: Larry Christenson (5-1) L: Steve Mura (4-7) S: Tug McGraw (15) | Sixth | 20 out |
| Saturday, August 30 |
| » Lost to Phillies (68-58), 6-1 | San Diego/Jack Murphy Stadium (30-30) | 53-76 | Lost 2 |
| » W: Dick Ruthven (13-8) L: Bob Shirley (9-10) | Sixth | 20½ out |
| » Defeated Phillies (68-59), 5-1 | San Diego/Jack Murphy Stadium (31-30) | 54-76 | |
| » W: John Curtis (6-8) L: Nino Espinosa (3-5) | Sixth | 20½ out |
| Sunday, August 31 |
| » Defeated Phillies (68-60), 10-3 | San Diego/Jack Murphy Stadium (32-30) | 55-76 | Won 2 |
| » W: Gary Lucas (5-7) L: Bob Walk (9-4) S: Rollie Fingers (18) | Sixth | 19½ out |
| Monday, September 1 |
| » Lost to Expos (70-61), 5-3 | San Diego/Jack Murphy Stadium (32-31) | 55-77 | |
| » W: Scott Sanderson (13-8) L: Rick Wise (5-6) S: Woodie Fryman (15) | Fifth | 20 out |
| Tuesday, September 2 |
| » Lost to Expos (71-61), 2-1 | San Diego/Jack Murphy Stadium (32-32) | 55-78 | Lost 2 |
| » W: Charlie Lea (5-5) L: Eric Rasmussen (3-10) S: Woodie Fryman (16) | Fifth | 20½ out |
| Wednesday, September 3 |
| » Defeated Expos (71-62), 4-3 | San Diego/Jack Murphy Stadium (33-32) | 56-78 | |
| » W: Steve Mura (5-7) L: Fred Norman (4-4) S: Rollie Fingers (19) | Sixth | 20½ out |
| Thursday, September 4 |
| » Defeated Mets (59-75), 3-2 | San Diego/Jack Murphy Stadium (34-32) | 57-78 | Won 2 |
| » W: John Curtis (7-8) L: Neil Allen (5-8) | Sixth | 19½ out |
| » Major-league debuts: Hubie Brooks (Mets) |
| Friday, September 5 |
| » Defeated Mets (59-76), 4-2 | San Diego/Jack Murphy Stadium (35-32) | 58-78 | Won 3 |
| » W: Juan Eichelberger (4-0) L: Mark Bomback (9-6) S: Gary Lucas (1) | Sixth | 19½ out |
| Saturday, September 6 |
| » Defeated Mets (59-77), 8-7 | San Diego/Jack Murphy Stadium (36-32) | 59-78 | Won 4 |
| » W: Rick Wise (6-6) L: Ray Burris (7-10) S: Rollie Fingers (20) | Sixth | 19½ out |
| Sunday, September 7 |
| » Defeated Mets (59-78), 5-2 | San Diego/Jack Murphy Stadium (37-32) | 60-78 | Won 5 |
| » W: Bob Shirley (10-10) L: John Pacella (3-4) S: Gary Lucas (2) | Sixth | 19½ out |
| Tuesday, September 9 |
| » Defeated Giants (67-71), 12-5 | San Diego/Jack Murphy Stadium (38-32) | 61-78 | Won 6 |
| » W: Steve Mura (6-7) L: Allen Ripley (7-9) | Sixth | 18½ out |
| Wednesday, September 10 |
| » Defeated Giants (67-72), 4-2 | San Diego/Jack Murphy Stadium (39-32) | 62-78 | Won 7 |
| » W: Rollie Fingers (10-8) L: Greg Minton (3-6) S: Gary Lucas (3) | Fifth | 17½ out |
| Friday, September 12 |
| » Lost to Braves (72-68), 6-2 | Atlanta-Fulton County Stadium (0-7) | 62-79 | |
| » W: Phil Niekro (14-14) L: Juan Eichelberger (4-1) S: Rick Camp (15) | Fifth | 18½ out |
| » Major-league debuts: Terry Harper (Braves) |
| Future Padre Sean Burroughs is born in Atlanta, GA. |
| Saturday, September 13 |
| » Lost to Braves (73-68), 5-3 | Atlanta-Fulton County Stadium (0-8) | 62-80 | Lost 2 |
| » W: Rick Matula (10-12) L: Rick Wise (6-7) S: Rick Camp (16) | Fifth | 19½ out |
| Sunday, September 14 |
| » Lost to Braves (74-68), 4-3 | Atlanta-Fulton County Stadium (0-9) | 62-81 | Lost 3 |
| » W: Rick Camp (6-4) L: Gary Lucas (5-8) | Fifth | 20½ out |
| Monday, September 15 |
| » Defeated Astros (82-61), 6-3 | Astrodome (4-4) | 63-81 | |
| » W: Bob Shirley (11-10) L: Nolan Ryan (9-9) | Fifth | 19½ out |
| Tuesday, September 16 |
| » Defeated Astros (82-62), 4-3 | Astrodome (5-4) | 64-81 | Won 2 |
| » W: John Curtis (8-8) L: Vern Ruhle (9-4) S: Rollie Fingers (21) | Fifth | 18½ out |
| Wednesday, September 17 |
| » Lost to Dodgers (83-62), 2-1 | Dodger Stadium (2-6) | 64-82 | |
| » W: Don Sutton (12-4) L: Juan Eichelberger (4-2) S: Steve Howe (17) | Sixth | 19½ out |
| Thursday, September 18 |
| » Lost to Dodgers (84-62), 7-3 | Dodger Stadium (2-7) | 64-83 | Lost 2 |
| » W: Bob Welch (13-9) L: Rick Wise (6-8) S: Bobby Castillo (5) | Sixth | 20½ out |
| Friday, September 19 |
| » Defeated Braves (77-70), 7-4 | San Diego/Jack Murphy Stadium (40-32) | 65-83 | |
| » W: Steve Mura (7-7) L: Doyle Alexander (13-9) S: Rollie Fingers (22) | Sixth | 19½ out |
| Saturday, September 20 |
| » Defeated Braves (77-71), 3-2 | San Diego/Jack Murphy Stadium (41-32) | 66-83 | Won 2 |
| » W: Eric Rasmussen (4-10) L: Al Hrabosky (4-2) | Fifth | 18½ out |
| Sunday, September 21 |
| » Defeated Braves (77-72), 3-1 | San Diego/Jack Murphy Stadium (42-32) | 67-83 | Won 3 |
| » W: Tom Tellmann (1-0) L: Phil Niekro (15-15) | Sixth | 18½ out |
| Monday, September 22 |
| » Lost to Astros (86-64), 4-2 | San Diego/Jack Murphy Stadium (42-33) | 67-84 | |
| » W: Joe Niekro (17-12) L: Bob Shirley (11-11) | Sixth | 19½ out |
| Tuesday, September 23 |
| » Defeated Astros (86-65), 9-4 | San Diego/Jack Murphy Stadium (43-33) | 68-84 | |
| » W: John Curtis (9-8) L: Randy Niemann (0-1) | Sixth | 18½ out |
| Wednesday, September 24 |
| » Lost to Reds (84-69), 7-6 | San Diego/Jack Murphy Stadium (43-34) | 68-85 | |
| » W: Doug Bair (2-6) L: Rollie Fingers (10-9) | Fifth | 18½ out |
| Thursday, September 25 |
| » Lost to Reds (85-69), 5-3 | San Diego/Jack Murphy Stadium (43-35) | 68-86 | Lost 2 |
| » W: Doug Bair (3-6) L: Dennis Kinney (4-6) | Sixth | 19½ out |
| Friday, September 26 |
| » Defeated Dodgers (86-68), 3-2 | San Diego/Jack Murphy Stadium (44-35) | 69-86 | |
| » W: Tom Tellmann (2-0) L: Dave Goltz (7-9) S: Rollie Fingers (23) | Sixth | 19½ out |
| Saturday, September 27 |
| » Lost to Dodgers (87-68), 6-4 | San Diego/Jack Murphy Stadium (44-36) | 69-87 | |
| » W: Don Sutton (13-5) L: Eric Rasmussen (4-11) S: Fernando Valenzuela (1) | Sixth | 20½ out |
| Sunday, September 28 |
| » Defeated Dodgers (87-69), 7-5 | San Diego/Jack Murphy Stadium (45-36) | 70-87 | |
| » W: Rollie Fingers (11-9) L: Steve Howe (6-9) S: Tom Tellmann (1) | Sixth | 19½ out |
| Tuesday, September 30 |
| » Defeated Reds (86-72), 3-2 | Riverfront Stadium (2-6) | 71-87 | Won 2 |
| » W: John Curtis (10-8) L: Charlie Leibrandt (10-9) | Sixth | 19½ out |
| Wednesday, October 1 |
| » Lost to Reds (87-72), 2-1 | Riverfront Stadium (2-7) | 71-88 | |
| » W: Tom Hume (9-10) L: Bob Shirley (11-12) | Sixth | 20½ out |
| Friday, October 3 |
| » Defeated Giants (74-85), 12-0 | Candlestick Park (2-5) | 72-88 | |
| » W: Steve Mura (8-7) L: Allen Ripley (9-10) | Sixth | 20 out |
| Saturday, October 4 |
| » Lost to Giants (75-85), 4-2 | Candlestick Park (2-6) | 72-89 | |
| » W: Tom Griffin (5-1) L: George Stablein (0-1) S: Greg Minton (19) | Sixth | 20 out |
| Sunday, October 5 |
| » Defeated Giants (75-86), 7-3 | Candlestick Park (3-6) | 73-89 | |
| » W: Tom Tellmann (3-0) L: Ed Whitson (11-13) | Fifth | 19 out |
| Sunday, November 30 |
| Future Padre Shane Victorino is born in Wailuku, HI. |
Game information provided by Retrosheet (www.retrosheet.org) |