| Wednesday, April 9 |
| » Defeated Blue Jays (0-1), 8-6 | Kingdome (1-0) | 1-0 | |
| » W: Mike Parrott (1-0) L: Dave Lemanczyk (0-1) S: Dave Heaverlo (1) | First | -- |
| Friday, April 11 |
| » Lost to Blue Jays (1-1), 10-7 | Kingdome (1-1) | 1-1 | |
| » W: Balor Moore (1-0) L: Rob Dressler (0-1) | Third | 1 out |
| Saturday, April 12 |
| » Defeated Blue Jays (1-2), 3-2 | Kingdome (2-1) | 2-1 | |
| » W: Rick Honeycutt (1-0) L: Jerry Garvin (0-1) | Second | ½ out |
| Sunday, April 13 |
| » Defeated Blue Jays (1-3), 5-1 | Kingdome (3-1) | 3-1 | Won 2 |
| » W: Floyd Bannister (1-0) L: Dave Lemanczyk (0-2) | First | -- |
| Monday, April 14 |
| » Defeated Athletics (2-3), 7-1 | Oakland-Alameda County Stadium (1-0) | 4-1 | Won 3 |
| » W: Glenn Abbott (1-0) L: Steve McCatty (0-2) | First | -- |
| Tuesday, April 15 |
| » Lost to Athletics (3-3), 12-3 | Oakland-Alameda County Stadium (1-1) | 4-2 | |
| » W: Steve McCatty (1-2) L: Mike Parrott (1-1) | Second | ½ out |
| Wednesday, April 16 |
| » Lost to Athletics (4-3), 6-1 | Oakland-Alameda County Stadium (1-2) | 4-3 | Lost 2 |
| » W: Matt Keough (2-0) L: Jim Beattie (0-1) | Third | 1 out |
| Thursday, April 17 |
| » Defeated Twins (3-5), 4-3 | Kingdome (4-1) | 5-3 | |
| » W: Rick Honeycutt (2-0) L: Geoff Zahn (1-1) | Third | ½ out |
| Friday, April 18 |
| » Defeated Twins (3-6), 3-1 | Kingdome (5-1) | 6-3 | Won 2 |
| » W: Floyd Bannister (2-0) L: Roger Erickson (0-2) | Second | 1 out |
| » Defeated Twins (3-7), 3-2 | Kingdome (6-1) | 7-3 | Won 3 |
| » W: Byron McLaughlin (1-0) L: Terry Felton (0-1) S: Shane Rawley (1) | Second | 1 out |
| Saturday, April 19 |
| » Lost to Twins (4-7), 8-3 | Kingdome (6-2) | 7-4 | |
| » W: Jerry Koosman (1-1) L: Glenn Abbott (1-1) | Third | 1 out |
| Sunday, April 20 |
| » Lost to Twins (5-7), 4-3 | Kingdome (6-3) | 7-5 | Lost 2 |
| » W: Pete Redfern (1-1) L: Mike Parrott (1-2) S: Mike Marshall (1) | Third | 1½ out |
| Monday, April 21 |
| » Lost to Athletics (9-3), 4-2 | Kingdome (6-4) | 7-6 | Lost 3 |
| » W: Jeff Jones (1-0) L: Shane Rawley (0-1) | Fourth | 2½ out |
| Tuesday, April 22 |
| » Defeated Athletics (9-4), 5-4 | Kingdome (7-4) | 8-6 | |
| » W: Rick Honeycutt (3-0) L: Brian Kingman (1-2) S: Byron McLaughlin (1) | Third | 1½ out |
| Wednesday, April 23 |
| » Lost to Athletics (10-4), 5-2 | Kingdome (7-5) | 8-7 | |
| » W: Rick Langford (1-0) L: Byron McLaughlin (1-1) | Fifth | 2½ out |
| Friday, April 25 |
| » Lost to Angels (6-7), 4-3 | Kingdome (7-6) | 8-8 | Lost 2 |
| » W: Don Aase (2-1) L: Mike Parrott (1-3) S: John Montague (2) | Fifth | 3 out |
| Saturday, April 26 |
| » Lost to Angels (7-7), 7-6 | Kingdome (7-7) | 8-9 | Lost 3 |
| » W: Dave LaRoche (1-0) L: Rob Dressler (0-2) S: Mark Clear (1) | Seventh | 4 out |
| Sunday, April 27 |
| » Defeated Angels (7-8), 7-3 | Kingdome (8-7) | 9-9 | |
| » W: Glenn Abbott (2-1) L: Dave Frost (2-2) | Fifth | 3 out |
| Monday, April 28 |
| » Defeated Twins (9-9), 6-4 | Metropolitan Stadium (1-0) | 10-9 | Won 2 |
| » W: Rick Honeycutt (4-0) L: Terry Felton (0-3) S: Dave Heaverlo (2) | Fourth | 2½ out |
| Tuesday, April 29 |
| » Defeated Twins (9-10), 5-3 | Metropolitan Stadium (2-0) | 11-9 | Won 3 |
| » W: Shane Rawley (1-1) L: Mike Marshall (0-2) | Fourth | 1½ out |
| Wednesday, April 30 |
| » Lost to Twins (10-10), 10-3 | Metropolitan Stadium (2-1) | 11-10 | |
| » W: Pete Redfern (3-1) L: Mike Parrott (1-4) | Fourth | 2½ out |
| Thursday, May 1 |
| » Lost to Angels (9-10), 2-1 | Anaheim Stadium (0-1) | 11-11 | Lost 2 |
| » W: John Montague (1-0) L: Jim Beattie (0-2) | Fifth | 2½ out |
| Friday, May 2 |
| » Lost to Angels (10-10), 3-1 | Anaheim Stadium (0-2) | 11-12 | Lost 3 |
| » W: Dave Frost (3-2) L: Glenn Abbott (2-2) | Fifth | 3 out |
| Saturday, May 3 |
| » Defeated Angels (10-11), 2-0 | Anaheim Stadium (1-2) | 12-12 | |
| » W: Rick Honeycutt (5-0) L: Bruce Kison (1-4) | Fifth | 3 out |
| Sunday, May 4 |
| » Lost to Angels (11-11), 4-3 | Anaheim Stadium (1-3) | 12-13 | |
| » W: Frank Tanana (2-2) L: Floyd Bannister (2-1) S: Mark Clear (2) | Fifth | 3½ out |
| Tuesday, May 6 |
| » Lost to Tigers (9-14), 9-5 | Kingdome (8-8) | 12-14 | Lost 2 |
| » W: Dan Petry (1-0) L: Jim Beattie (0-3) S: Aurelio Lopez (3) | Sixth | 4 out |
| Wednesday, May 7 |
| » Defeated Tigers (9-15), 7-6 | Kingdome (9-8) | 13-14 | |
| » W: Dave Heaverlo (1-0) L: Pat Underwood (0-2) | Fifth | 3 out |
| Thursday, May 8 |
| » Defeated Tigers (9-16), 4-3 | Kingdome (10-8) | 14-14 | Won 2 |
| » W: Rick Honeycutt (6-0) L: Jack Morris (3-4) | Fifth | 2½ out |
| Friday, May 9 |
| » Lost to Indians (10-14), 4-1 | Kingdome (10-9) | 14-15 | |
| » W: Dan Spillner (2-1) L: Floyd Bannister (2-2) | Fifth | 3 out |
| Saturday, May 10 |
| » Lost to Indians (11-14), 5-3 | Kingdome (10-10) | 14-16 | Lost 2 |
| » W: John Denny (2-3) L: Byron McLaughlin (1-2) S: Victor Cruz (1) | Fourth | 4 out |
| Sunday, May 11 |
| » Defeated Indians (11-15), 9-4 | Kingdome (11-10) | 15-16 | |
| » W: Jim Beattie (1-3) L: Len Barker (4-2) | Fifth | 4 out |
| Wednesday, May 14 |
| » Defeated Blue Jays (15-12), 7-0 | Exhibition Stadium (1-0) | 16-16 | Won 2 |
| » W: Glenn Abbott (3-2) L: Paul Mirabella (3-2) | Fifth | 2½ out |
| Thursday, May 15 |
| » Lost to Blue Jays (16-12), 1-0 | Exhibition Stadium (1-1) | 16-17 | |
| » W: Jim Clancy (2-1) L: Floyd Bannister (2-3) | Fifth | 3 out |
| Friday, May 16 |
| » Defeated White Sox (18-15), 4-2 | Comiskey Park I (1-0) | 17-17 | |
| » W: Jim Beattie (2-3) L: Steve Trout (1-3) S: Shane Rawley (2) | Fifth | 2 out |
| Saturday, May 17 |
| » Lost to White Sox (19-15), 4-0 | Comiskey Park I (1-1) | 17-18 | |
| » W: Britt Burns (5-2) L: Rick Honeycutt (6-1) | Fourth | 3 out |
| Sunday, May 18 |
| » Lost to White Sox (20-15), 6-5 | Comiskey Park I (1-2) | 17-19 | Lost 2 |
| » W: Francisco Barrios (1-0) L: Rob Dressler (0-3) S: Ed Farmer (10) | Fourth | 3½ out |
| Monday, May 19 |
| » Defeated Brewers (15-17), 4-3 | Kingdome (12-10) | 18-19 | |
| » W: Shane Rawley (2-1) L: Bill Castro (0-1) | Fifth | 3½ out |
| Tuesday, May 20 |
| » Lost to Brewers (16-17), 14-5 | Kingdome (12-11) | 18-20 | |
| » W: Lary Sorensen (3-3) L: Floyd Bannister (2-4) | Fifth | 4½ out |
| Wednesday, May 21 |
| » Defeated Brewers (16-18), 6-5 | Kingdome (13-11) | 19-20 | |
| » W: Jim Beattie (3-3) L: Mike Caldwell (3-2) S: Dave Heaverlo (3) | Fifth | 3½ out |
| Friday, May 23 |
| » Defeated White Sox (22-17), 8-0 | Kingdome (14-11) | 20-20 | Won 2 |
| » W: Rick Honeycutt (7-1) L: Britt Burns (5-3) S: Shane Rawley (3) | Fifth | 3 out |
| Saturday, May 24 |
| » Defeated White Sox (22-18), 5-4 | Kingdome (15-11) | 21-20 | Won 3 |
| » W: Glenn Abbott (4-2) L: Ken Kravec (2-4) S: Dave Roberts (1) | Fifth | 3 out |
| Sunday, May 25 |
| » Defeated White Sox (22-19), 8-3 | Kingdome (16-11) | 22-20 | Won 4 |
| » W: Floyd Bannister (3-4) L: Randy Scarbery (1-2) | Fourth | 3 out |
| Monday, May 26 |
| » Lost to Brewers (20-18), 11-1 | County Stadium (0-1) | 22-21 | |
| » W: Mike Caldwell (4-2) L: Mike Parrott (1-5) | Fifth | 3 out |
| Tuesday, May 27 |
| » Lost to Brewers (21-18), 4-1 | County Stadium (0-2) | 22-22 | Lost 2 |
| » W: Rickey Keeton (1-0) L: Jim Beattie (3-4) S: Bob McClure (4) | Fifth | 4 out |
| Wednesday, May 28 |
| » Lost to Brewers (22-18), 7-0 | County Stadium (0-3) | 22-23 | Lost 3 |
| » W: Bill Travers (3-2) L: Byron McLaughlin (1-3) S: Reggie Cleveland (3) | Fifth | 4 out |
| Thursday, May 29 |
| Future Mariner Cha Seung Baek is born in Pusan, South Korea. |
| Friday, May 30 |
| » Defeated Indians (20-23), 4-3 | Cleveland Stadium (1-0) | 23-23 | |
| » W: Dave Heaverlo (2-0) L: Sid Monge (0-2) | Fifth | 4 out |
| Saturday, May 31 |
| » Lost to Indians (21-23), 5-2 | Cleveland Stadium (1-1) | 23-24 | |
| » W: Dan Spillner (4-3) L: Mike Parrott (1-6) | Fifth | 5 out |
| Sunday, June 1 |
| » Defeated Indians (21-24), 8-7 | Cleveland Stadium (2-1) | 24-24 | |
| » W: Dave Heaverlo (3-0) L: Sid Monge (0-3) | Fifth | 4 out |
| Monday, June 2 |
| » Tied Tigers, 3-3 | Tiger Stadium (0-0) | 24-24 | |
| » Starters: Rick Honeycutt vs Jack Morris | Fourth | 3½ out |
| Tuesday, June 3 |
| » Lost to Tigers (20-25), 4-2 | Tiger Stadium (0-1) | 24-25 | |
| » W: Aurelio Lopez (5-3) L: Byron McLaughlin (1-4) | Fourth | 4½ out |
| Wednesday, June 4 |
| » Lost to Tigers (21-25), 8-2 | Tiger Stadium (0-2) | 24-26 | Lost 2 |
| » W: Milt Wilcox (4-4) L: Floyd Bannister (3-5) | Fifth | 5½ out |
| Friday, June 6 |
| » Lost to Yankees (31-18), 3-0 | Kingdome (16-12) | 24-27 | Lost 3 |
| » W: Tommy John (8-2) L: Jim Beattie (3-5) | Fourth | 7 out |
| Saturday, June 7 |
| » Lost to Yankees (32-18), 1-0 | Kingdome (16-13) | 24-28 | Lost 4 |
| » W: Tom Underwood (6-3) L: Rick Honeycutt (7-2) S: Rich Gossage (6) | Fourth | 8 out |
| Sunday, June 8 |
| » Defeated Yankees (32-19), 5-0 | Kingdome (17-13) | 25-28 | |
| » W: Glenn Abbott (5-2) L: Ron Guidry (6-2) | Fourth | 8 out |
| Monday, June 9 |
| » Defeated Red Sox (25-27), 8-7 | Kingdome (18-13) | 26-28 | Won 2 |
| » W: Dave Heaverlo (4-0) L: Dick Drago (2-3) | Third | 7½ out |
| Tuesday, June 10 |
| » Lost to Red Sox (26-27), 5-4 | Kingdome (18-14) | 26-29 | |
| » W: Skip Lockwood (3-1) L: Rob Dressler (0-4) | Fourth | 8½ out |
| Wednesday, June 11 |
| » Lost to Red Sox (27-27), 7-5 | Kingdome (18-15) | 26-30 | Lost 2 |
| » W: Chuck Rainey (7-1) L: Jim Beattie (3-6) S: Tom Burgmeier (10) | Fourth | 9 out |
| Thursday, June 12 |
| » Lost to Orioles (28-28), 4-1 | Kingdome (18-16) | 26-31 | Lost 3 |
| » W: Steve Stone (7-3) L: Rick Honeycutt (7-3) | Fourth | 9½ out |
| Friday, June 13 |
| » Defeated Orioles (28-29), 7-6 | Kingdome (19-16) | 27-31 | |
| » W: Glenn Abbott (6-2) L: Mike Flanagan (6-5) S: Dave Heaverlo (4) | Fourth | 9½ out |
| Saturday, June 14 |
| » Defeated Orioles (28-30), 9-8 | Kingdome (20-16) | 28-31 | Won 2 |
| » W: Dave Roberts (1-1) L: Paul Hartzell (0-2) S: Shane Rawley (4) | Fourth | 8½ out |
| Sunday, June 15 |
| » Lost to Orioles (29-30), 9-3 | Kingdome (20-17) | 28-32 | |
| » W: Sammy Stewart (3-6) L: Floyd Bannister (3-6) | Fourth | 9½ out |
| Monday, June 16 |
| » Lost to Yankees (38-21), 6-3 | Yankee Stadium (0-1) | 28-33 | Lost 2 |
| » W: Tommy John (9-2) L: Jim Beattie (3-7) S: Rich Gossage (9) | Fourth | 9½ out |
| Tuesday, June 17 |
| » Lost to Yankees (39-21), 8-2 | Yankee Stadium (0-2) | 28-34 | Lost 3 |
| » W: Tom Underwood (7-3) L: Rick Honeycutt (7-4) S: Ron Davis (2) | Fourth | 10½ out |
| Wednesday, June 18 |
| » Lost to Red Sox (33-28), 6-2 | Fenway Park (0-1) | 28-35 | Lost 4 |
| » W: Dennis Eckersley (3-5) L: Glenn Abbott (6-3) | Fifth | 11½ out |
| Thursday, June 19 |
| » Lost to Red Sox (34-28), 2-0 | Fenway Park (0-2) | 28-36 | Lost 5 |
| » W: Bob Stanley (6-5) L: Mike Parrott (1-7) | Fifth | 11½ out |
| Friday, June 20 |
| » Defeated Orioles (33-31), 3-1 | Memorial Stadium (1-0) | 29-36 | |
| » W: Floyd Bannister (4-6) L: Jim Palmer (6-4) | Fifth | 10½ out |
| Saturday, June 21 |
| » Lost to Orioles (34-31), 9-0 | Memorial Stadium (1-1) | 29-37 | |
| » W: Steve Stone (9-3) L: Dave Roberts (1-2) | Fifth | 10½ out |
| Sunday, June 22 |
| » Defeated Orioles (34-32), 7-5 | Memorial Stadium (2-1) | 30-37 | |
| » W: Shane Rawley (3-1) L: Tim Stoddard (0-3) | Fifth | 10½ out |
| Tuesday, June 24 |
| » Lost to Rangers (31-36), 5-4 | Arlington Stadium (0-1) | 30-38 | |
| » W: Sparky Lyle (3-1) L: Shane Rawley (3-2) | Fifth | 10½ out |
| Wednesday, June 25 |
| » Lost to Rangers (32-36), 6-1 | Arlington Stadium (0-2) | 30-39 | Lost 2 |
| » W: Fergie Jenkins (6-5) L: Mike Parrott (1-8) | Fifth | 11½ out |
| Thursday, June 26 |
| » Defeated Rangers (32-37), 8-4 | Arlington Stadium (1-2) | 31-39 | |
| » W: Floyd Bannister (5-6) L: Jon Matlack (4-4) S: Shane Rawley (5) | Fourth | 11 out |
| Friday, June 27 |
| » Lost to Royals (43-28), 2-1 | Kingdome (20-18) | 31-40 | |
| » W: Rich Gale (5-7) L: Rick Honeycutt (7-5) S: Dan Quisenberry (14) | Fifth | 12 out |
| Saturday, June 28 |
| » Lost to Royals (44-28), 4-2 | Kingdome (20-19) | 31-41 | Lost 2 |
| » W: Larry Gura (10-3) L: Dave Roberts (1-3) | Fifth | 13 out |
| Sunday, June 29 |
| » Defeated Royals (44-29), 7-2 | Kingdome (21-19) | 32-41 | |
| » W: Glenn Abbott (7-3) L: Dennis Leonard (7-7) | Fourth | 12 out |
| Monday, June 30 |
| » Lost to Rangers (35-38), 11-5 | Kingdome (21-20) | 32-42 | |
| » W: Fergie Jenkins (7-5) L: Mike Parrott (1-9) | Fourth | 12 out |
| Tuesday, July 1 |
| » Defeated Rangers (35-39), 6-5 | Kingdome (22-20) | 33-42 | |
| » W: Shane Rawley (4-2) L: Jim Kern (2-10) | Fourth | 11 out |
| Wednesday, July 2 |
| » Lost to Rangers (36-39), 6-3 | Kingdome (22-21) | 33-43 | |
| » W: Gaylord Perry (5-6) L: Rick Honeycutt (7-6) | Fourth | 12 out |
| Thursday, July 3 |
| » Defeated Royals (45-32), 13-2 | Royals Stadium (1-0) | 34-43 | |
| » W: Jim Beattie (4-7) L: Larry Gura (10-4) S: Shane Rawley (6) | Fourth | 11 out |
| Friday, July 4 |
| » Lost to Royals (46-32), 5-3 | Royals Stadium (1-1) | 34-44 | |
| » W: Dan Quisenberry (6-4) L: Dave Roberts (1-4) | Fifth | 12 out |
| Saturday, July 5 |
| » Lost to Royals (47-32), 5-4 | Royals Stadium (1-2) | 34-45 | Lost 2 |
| » W: Jeff Twitty (1-0) L: Mike Parrott (1-10) S: Dan Quisenberry (15) | Sixth | 13 out |
| Sunday, July 6 |
| » Defeated Royals (47-33), 5-3 | Royals Stadium (2-2) | 35-45 | |
| » W: Floyd Bannister (6-6) L: Paul Splittorff (5-6) S: Shane Rawley (7) | Sixth | 12 out |
| Thursday, July 10 |
| » Lost to Twins (36-44), 12-4 | Kingdome (22-22) | 35-46 | |
| » W: Jerry Koosman (7-8) L: Rick Honeycutt (7-7) | Sixth | 13 out |
| Friday, July 11 |
| » Lost to Twins (37-44), 6-3 | Kingdome (22-23) | 35-47 | Lost 2 |
| » W: Darrell Jackson (7-4) L: Glenn Abbott (7-4) S: Doug Corbett (9) | Sixth | 14 out |
| Saturday, July 12 |
| » Lost to Twins (38-44), 8-3 | Metropolitan Stadium (2-2) | 35-48 | Lost 3 |
| » W: Geoff Zahn (8-10) L: Floyd Bannister (6-7) | Fifth | 14 out |
| Sunday, July 13 |
| » Lost to Twins (39-44), 7-6 | Metropolitan Stadium (2-3) | 35-49 | Lost 4 |
| » W: Doug Corbett (6-2) L: Shane Rawley (4-3) | Fourth | 15 out |
| Monday, July 14 |
| » Defeated Twins (39-45), 8-5 | Metropolitan Stadium (3-3) | 36-49 | |
| » W: Rick Honeycutt (8-7) L: Fernando Arroyo (1-2) S: Dave Roberts (2) | Fifth | 15 out |
| Wednesday, July 16 |
| » Lost to Blue Jays (36-47), 5-0 | Kingdome (22-24) | 36-50 | |
| » W: Dave Stieb (9-6) L: Glenn Abbott (7-5) | Fifth | 16½ out |
| Thursday, July 17 |
| » Defeated Blue Jays (36-48), 5-3 | Kingdome (23-24) | 37-50 | |
| » W: Shane Rawley (5-3) L: Jesse Jefferson (2-6) | Fifth | 15½ out |
| Friday, July 18 |
| » Lost to Tigers (45-38), 5-3 | Kingdome (23-25) | 37-51 | |
| » W: Aurelio Lopez (7-3) L: Jim Beattie (4-8) | Fifth | 16½ out |
| Saturday, July 19 |
| » Lost to Tigers (46-38), 5-3 | Kingdome (23-26) | 37-52 | Lost 2 |
| » W: Dave Rozema (5-5) L: Rick Honeycutt (8-8) | Fifth | 16½ out |
| Sunday, July 20 |
| » Lost to Tigers (47-38), 5-2 | Kingdome (23-27) | 37-53 | Lost 3 |
| » W: Dan Schatzeder (5-6) L: Mike Parrott (1-11) | Sixth | 17½ out |
| Monday, July 21 |
| » Defeated Indians (41-47), 7-0 | Kingdome (24-27) | 38-53 | |
| » W: Glenn Abbott (8-5) L: Wayne Garland (4-3) | Sixth | 17½ out |
| Tuesday, July 22 |
| » Lost to Indians (42-47), 4-0 | Kingdome (24-28) | 38-54 | |
| » W: Len Barker (10-7) L: Floyd Bannister (6-8) | Sixth | 17½ out |
| Wednesday, July 23 |
| » Lost to Indians (43-47), 12-6 | Kingdome (24-29) | 38-55 | Lost 2 |
| » W: Victor Cruz (5-5) L: Shane Rawley (5-4) | Sixth | 18½ out |
| Friday, July 25 |
| » Lost to Blue Jays (41-51), 5-3 | Exhibition Stadium (1-2) | 38-56 | Lost 3 |
| » W: Jim Clancy (9-7) L: Rick Honeycutt (8-9) | Sixth | 20 out |
| Saturday, July 26 |
| » Defeated Blue Jays (41-52), 7-2 | Exhibition Stadium (2-2) | 39-56 | |
| » W: Rob Dressler (1-4) L: Dave Stieb (10-7) | Sixth | 19½ out |
| » Lost to Blue Jays (42-52), 7-5 | Exhibition Stadium (2-3) | 39-57 | |
| » W: Jack Kucek (3-3) L: Glenn Abbott (8-6) S: Jerry Garvin (6) | Sixth | 19½ out |
| Sunday, July 27 |
| » Lost to Blue Jays (43-52), 5-0 | Exhibition Stadium (2-4) | 39-58 | Lost 2 |
| » W: Jesse Jefferson (4-6) L: Floyd Bannister (6-9) | Sixth | 20½ out |
| Monday, July 28 |
| » Lost to Indians (47-47), 7-3 | Cleveland Stadium (2-2) | 39-59 | Lost 3 |
| » W: Len Barker (11-7) L: Jim Beattie (4-9) S: Victor Cruz (5) | Sixth | 21 out |
| Tuesday, July 29 |
| » Lost to Indians (48-47), 7-2 | Cleveland Stadium (2-3) | 39-60 | Lost 4 |
| » W: Dan Spillner (8-8) L: Rick Honeycutt (8-10) S: Sid Monge (8) | Sixth | 22 out |
| Wednesday, July 30 |
| » Lost to Indians (49-47), 5-2 | Cleveland Stadium (2-4) | 39-61 | Lost 5 |
| » W: Ross Grimsley (4-4) L: Glenn Abbott (8-7) | Sixth | 22 out |
| Friday, August 1 |
| » Lost to Tigers (53-44), 1-0 | Tiger Stadium (0-3) | 39-62 | Lost 6 |
| » W: Jack Morris (12-9) L: Floyd Bannister (6-10) | Sixth | 24 out |
| » Lost to Tigers (54-44), 5-2 | Tiger Stadium (0-4) | 39-63 | Lost 7 |
| » W: Dan Petry (6-6) L: Rob Dressler (1-5) S: Aurelio Lopez (14) | Sixth | 24 out |
| Saturday, August 2 |
| » Lost to Tigers (55-44), 9-3 | Tiger Stadium (0-5) | 39-64 | Lost 8 |
| » W: Bruce Robbins (2-2) L: Jim Beattie (4-10) S: Aurelio Lopez (15) | Sixth | 25 out |
| Sunday, August 3 |
| » Lost to Tigers (56-44), 4-3 | Tiger Stadium (0-6) | 39-65 | Lost 9 |
| » W: Dave Rozema (6-6) L: Rick Honeycutt (8-11) S: Aurelio Lopez (16) | Sixth | 25 out |
| Monday, August 4 |
| » Lost to Angels (39-64), 8-3 | Anaheim Stadium (1-4) | 39-66 | Lost 10 |
| » Manager: Maury Wills |
| » W: Andy Hassler (2-0) L: Shane Rawley (5-5) | Seventh | 26 out |
| Tuesday, August 5 |
| » Lost to Angels (40-64), 5-4 | Anaheim Stadium (1-5) | 39-67 | Lost 11 |
| » W: Mark Clear (8-9) L: Dave Heaverlo (4-1) | Seventh | 27 out |
| Wednesday, August 6 |
| » Lost to Angels (41-64), 8-3 | Anaheim Stadium (1-6) | 39-68 | Lost 12 |
| » W: John Montague (4-2) L: Rob Dressler (1-6) | Seventh | 28 out |
| Friday, August 8 |
| » Defeated Athletics (56-54), 2-1 | Oakland-Alameda County Stadium (2-2) | 40-68 | |
| » W: Shane Rawley (6-5) L: Matt Keough (12-11) S: Dave Roberts (3) | Seventh | 28½ out |
| Saturday, August 9 |
| » Lost to Athletics (57-54), 2-1 | Oakland-Alameda County Stadium (2-3) | 40-69 | |
| » W: Mike Norris (15-7) L: Rick Honeycutt (8-12) | Seventh | 28½ out |
| Sunday, August 10 |
| » Defeated Athletics (57-55), 2-1 | Oakland-Alameda County Stadium (3-3) | 41-69 | |
| » W: Dave Heaverlo (5-1) L: Steve McCatty (9-10) S: Shane Rawley (8) | Seventh | 29 out |
| » Lost to Athletics (58-55), 6-1 | Oakland-Alameda County Stadium (3-4) | 41-70 | |
| » W: Rick Langford (12-9) L: Byron McLaughlin (1-5) | Seventh | 29 out |
| Tuesday, August 12 |
| » Lost to Angels (45-65), 9-6 | Kingdome (24-30) | 41-71 | Lost 2 |
| » W: Mark Clear (9-9) L: Dave Heaverlo (5-2) | Seventh | 29½ out |
| Wednesday, August 13 |
| » Lost to Angels (46-65), 10-4 | Kingdome (24-31) | 41-72 | Lost 3 |
| » W: Andy Hassler (4-0) L: Shane Rawley (6-6) | Seventh | 30½ out |
| Thursday, August 14 |
| » Lost to Angels (47-65), 2-1 | Kingdome (24-32) | 41-73 | Lost 4 |
| » W: Alfredo Martinez (3-4) L: Rick Honeycutt (8-13) S: Don Aase (1) | Seventh | 31 out |
| Friday, August 15 |
| » Lost to Athletics (61-56), 11-3 | Kingdome (24-33) | 41-74 | Lost 5 |
| » W: Rick Langford (13-9) L: Glenn Abbott (8-8) | Sixth | 32 out |
| Saturday, August 16 |
| » Lost to Athletics (62-56), 8-3 | Kingdome (24-34) | 41-75 | Lost 6 |
| » W: Steve McCatty (10-10) L: Byron McLaughlin (1-6) | Sixth | 33 out |
| Sunday, August 17 |
| » Defeated Athletics (62-57), 4-3 | Kingdome (25-34) | 42-75 | |
| » W: Rob Dressler (2-6) L: Brian Kingman (7-13) S: Shane Rawley (9) | Seventh | 33 out |
| Tuesday, August 19 |
| » Lost to Yankees (72-46), 3-1 | Kingdome (25-35) | 42-76 | |
| » W: Tom Underwood (10-9) L: Rick Honeycutt (8-14) S: Rich Gossage (19) | Seventh | 34½ out |
| Wednesday, August 20 |
| » Lost to Yankees (73-46), 6-4 | Kingdome (25-36) | 42-77 | Lost 2 |
| » W: Tommy John (17-6) L: Glenn Abbott (8-9) S: Rich Gossage (20) | Seventh | 35½ out |
| Thursday, August 21 |
| » Defeated Yankees (73-47), 6-4 | Kingdome (26-36) | 43-77 | |
| » W: Dave Roberts (2-4) L: Gaylord Perry (7-10) S: Shane Rawley (10) | Seventh | 34½ out |
| Friday, August 22 |
| » Lost to Red Sox (63-55), 1-0 | Kingdome (26-37) | 43-78 | |
| » W: Steve Renko (8-5) L: Jim Beattie (4-11) S: Bob Stanley (10) | Seventh | 34½ out |
| Saturday, August 23 |
| » Defeated Red Sox (63-56), 3-1 | Kingdome (27-37) | 44-78 | |
| » W: Rob Dressler (3-6) L: Bruce Hurst (2-2) S: Shane Rawley (11) | Seventh | 34½ out |
| Sunday, August 24 |
| » Lost to Red Sox (64-56), 10-7 | Kingdome (27-38) | 44-79 | |
| » W: Bill Campbell (3-0) L: Rick Honeycutt (8-15) | Seventh | 35½ out |
| Monday, August 25 |
| » Defeated Orioles (74-49), 10-5 | Kingdome (28-38) | 45-79 | |
| » W: Glenn Abbott (9-9) L: Dennis Martinez (3-3) S: Shane Rawley (12) | Seventh | 35½ out |
| Tuesday, August 26 |
| » Defeated Orioles (74-50), 2-1 | Kingdome (29-38) | 46-79 | Won 2 |
| » W: Floyd Bannister (7-10) L: Scott McGregor (15-7) | Seventh | 35½ out |
| Thursday, August 28 |
| » Lost to Yankees (76-50), 6-5 | Yankee Stadium (0-3) | 46-80 | |
| » W: Ron Guidry (13-9) L: Jim Beattie (4-12) | Seventh | 36 out |
| Friday, August 29 |
| » Lost to Yankees (77-50), 5-1 | Yankee Stadium (0-4) | 46-81 | Lost 2 |
| » W: Tommy John (18-7) L: Rob Dressler (3-7) | Seventh | 37 out |
| Saturday, August 30 |
| » Lost to Yankees (78-50), 9-3 | Yankee Stadium (0-5) | 46-82 | Lost 3 |
| » W: Gaylord Perry (8-10) L: Glenn Abbott (9-10) | Seventh | 37 out |
| Sunday, August 31 |
| » Defeated Yankees (78-51), 1-0 | Yankee Stadium (1-5) | 47-82 | |
| » W: Shane Rawley (7-6) L: Ron Guidry (13-10) | Seventh | 37 out |
| Monday, September 1 |
| » Lost to Orioles (77-52), 5-4 | Memorial Stadium (2-2) | 47-83 | |
| » W: Dennis Martinez (4-3) L: Mike Parrott (1-12) S: Tippy Martinez (10) | Seventh | 37 out |
| Tuesday, September 2 |
| » Lost to Orioles (78-52), 10-4 | Memorial Stadium (2-3) | 47-84 | Lost 2 |
| » W: Jim Palmer (15-9) L: Jim Beattie (4-13) | Seventh | 37½ out |
| Wednesday, September 3 |
| » Lost to Orioles (79-52), 5-1 | Memorial Stadium (2-4) | 47-85 | Lost 3 |
| » W: Steve Stone (22-5) L: Rob Dressler (3-8) | Seventh | 37½ out |
| Thursday, September 4 |
| » Defeated Red Sox (72-58), 7-4 | Fenway Park (1-2) | 48-85 | |
| » W: Glenn Abbott (10-10) L: Dennis Eckersley (9-12) S: Manny Sarmiento (1) | Seventh | 36½ out |
| » Major-league debuts: Luis Aponte (Red Sox) |
| Friday, September 5 |
| » Defeated Red Sox (72-59), 4-2 | Fenway Park (2-2) | 49-85 | Won 2 |
| » W: Floyd Bannister (8-10) L: John Tudor (6-3) S: Shane Rawley (13) | Seventh | 36½ out |
| Saturday, September 6 |
| » Lost to Red Sox (73-59), 5-1 | Fenway Park (2-3) | 49-86 | |
| » W: Dick Drago (6-5) L: Mike Parrott (1-13) S: Tom Burgmeier (21) | Seventh | 36½ out |
| Sunday, September 7 |
| » Defeated Red Sox (73-60), 12-6 | Fenway Park (3-3) | 50-86 | |
| » W: Byron McLaughlin (2-6) L: Steve Renko (9-6) | Seventh | 36½ out |
| » Major-league debuts: Rich Gedman (Red Sox) |
| Monday, September 8 |
| » Lost to White Sox (58-78), 3-2 | Comiskey Park I (1-3) | 50-87 | |
| » W: Ed Farmer (7-8) L: Dave Heaverlo (5-3) | Seventh | 36½ out |
| Tuesday, September 9 |
| » Defeated White Sox (58-79), 4-1 | Comiskey Park I (2-3) | 51-87 | |
| » W: Rick Honeycutt (9-15) L: Ross Baumgarten (2-10) S: Byron McLaughlin (2) | Seventh | 35½ out |
| Wednesday, September 10 |
| » Lost to White Sox (59-79), 4-3 | Comiskey Park I (2-4) | 51-88 | |
| » W: La Marr Hoyt (8-2) L: Manny Sarmiento (0-1) S: Ed Farmer (25) | Seventh | 35½ out |
| Friday, September 12 |
| » Lost to Brewers (75-67), 7-1 | Kingdome (29-39) | 51-89 | Lost 2 |
| » W: Moose Haas (16-12) L: Floyd Bannister (8-11) | Seventh | 36 out |
| Saturday, September 13 |
| » Lost to Brewers (76-67), 8-0 | Kingdome (29-40) | 51-90 | Lost 3 |
| » W: Mike Caldwell (13-10) L: Mike Parrott (1-14) | Seventh | 36 out |
| Sunday, September 14 |
| » Lost to Brewers (77-67), 3-2 | Kingdome (29-41) | 51-91 | Lost 4 |
| » W: Bob McClure (3-7) L: Rick Honeycutt (9-16) S: Reggie Cleveland (4) | Seventh | 37 out |
| Monday, September 15 |
| » Defeated White Sox (60-82), 12-1 | Kingdome (30-41) | 52-91 | |
| » W: Rob Dressler (4-8) L: La Marr Hoyt (8-3) | Seventh | 36½ out |
| Tuesday, September 16 |
| » Lost to White Sox (61-82), 2-1 | Kingdome (30-42) | 52-92 | |
| » W: Richard Dotson (11-9) L: Glenn Abbott (10-11) S: Ed Farmer (27) | Seventh | 37 out |
| Wednesday, September 17 |
| » Defeated White Sox (61-83), 4-0 | Kingdome (31-42) | 53-92 | |
| » W: Floyd Bannister (9-11) L: Britt Burns (13-13) S: Mike Parrott (1) | Seventh | 36½ out |
| Thursday, September 18 |
| » Lost to White Sox (62-83), 5-4 | Kingdome (31-43) | 53-93 | |
| » W: Mike Proly (4-9) L: Shane Rawley (7-7) S: Guy Hoffman (1) | Seventh | 37½ out |
| Friday, September 19 |
| » Lost to Brewers (80-69), 4-0 | County Stadium (0-4) | 53-94 | Lost 2 |
| » W: Bob McClure (4-7) L: Rick Honeycutt (9-17) | Seventh | 38½ out |
| Saturday, September 20 |
| » Lost to Brewers (81-69), 8-4 | County Stadium (0-5) | 53-95 | Lost 3 |
| » W: Dave LaPoint (1-0) L: Rob Dressler (4-9) S: Bill Castro (8) | Seventh | 38½ out |
| Sunday, September 21 |
| » Defeated Brewers (81-70), 7-5 | County Stadium (1-5) | 54-95 | |
| » W: Glenn Abbott (11-11) L: Paul Mitchell (5-5) S: Mike Parrott (2) | Sixth | 37½ out |
| Monday, September 22 |
| » Defeated Royals (92-59), 5-4 | Kingdome (32-43) | 55-95 | Won 2 |
| » W: Byron McLaughlin (3-6) L: Dan Quisenberry (11-7) | Seventh | 36½ out |
| Tuesday, September 23 |
| » Defeated Royals (92-60), 7-3 | Kingdome (33-43) | 56-95 | Won 3 |
| » W: Jim Beattie (5-13) L: Renie Martin (9-10) | Seventh | 35½ out |
| Wednesday, September 24 |
| » Defeated Royals (92-61), 4-2 | Kingdome (34-43) | 57-95 | Won 4 |
| » W: Rick Honeycutt (10-17) L: Paul Splittorff (13-11) S: Mike Parrott (3) | Seventh | 34½ out |
| Thursday, September 25 |
| » Defeated Rangers (71-82), 7-6 | Kingdome (35-43) | 58-95 | Won 5 |
| » W: Dave Heaverlo (6-3) L: Danny Darwin (12-4) | Sixth | 34 out |
| Friday, September 26 |
| » Defeated Rangers (71-83), 7-2 | Kingdome (36-43) | 59-95 | Won 6 |
| » W: Glenn Abbott (12-11) L: Fergie Jenkins (12-11) | Sixth | 33 out |
| Saturday, September 27 |
| » Lost to Rangers (72-83), 7-3 | Kingdome (36-44) | 59-96 | |
| » W: Doc Medich (13-11) L: Floyd Bannister (9-12) | Seventh | 33 out |
| Sunday, September 28 |
| » Lost to Rangers (73-83), 4-1 | Kingdome (36-45) | 59-97 | Lost 2 |
| » W: John Butcher (2-3) L: Jim Beattie (5-14) S: Danny Darwin (8) | Seventh | 33 out |
| Tuesday, September 30 |
| » Lost to Royals (93-64), 7-5 | Royals Stadium (2-3) | 59-98 | Lost 3 |
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