| Friday, April 11 |
| » Defeated Indians (0-1), 10-2 | Anaheim Stadium (1-0) | 1-0 | |
| » W: Dave Frost (1-0) L: Dan Spillner (0-1) | Second | ½ out |
| » Major-league debuts: Joe Charboneau and Jerry Dybzinski (Indians) |
| Saturday, April 12 |
| » Lost to Indians (1-1), 2-1 | Anaheim Stadium (1-1) | 1-1 | |
| » W: Len Barker (1-0) L: Bruce Kison (0-1) S: Sid Monge (1) | Third | 1 out |
| Sunday, April 13 |
| » Defeated Indians (1-2), 8-3 | Anaheim Stadium (2-1) | 2-1 | |
| » W: Don Aase (1-0) L: John Denny (0-1) S: John Montague (1) | Second | ½ out |
| Monday, April 14 |
| » Lost to Twins (3-2), 5-3 | Anaheim Stadium (2-2) | 2-2 | |
| » W: Doug Corbett (2-0) L: Mark Clear (0-1) | Fourth | 1½ out |
| Tuesday, April 15 |
| » Defeated Twins (3-3), 3-1 | Anaheim Stadium (3-2) | 3-2 | |
| » W: Frank Tanana (1-0) L: Jerry Koosman (0-1) | Third | 1 out |
| Wednesday, April 16 |
| » Defeated Twins (3-4), 2-1 | Anaheim Stadium (4-2) | 4-2 | Won 2 |
| » W: Dave Frost (2-0) L: Mike Marshall (0-1) | Second | ½ out |
| Friday, April 18 |
| » Lost to Athletics (5-3), 6-3 | Oakland-Alameda County Stadium (0-1) | 4-3 | |
| » W: Brian Kingman (1-1) L: Bruce Kison (0-2) | Fourth | 1½ out |
| Saturday, April 19 |
| » Lost to Athletics (6-3), 3-1 | Oakland-Alameda County Stadium (0-2) | 4-4 | Lost 2 |
| » W: Mike Norris (2-0) L: Don Aase (1-1) S: Jeff Jones (1) | Fourth | 2½ out |
| Sunday, April 20 |
| » Lost to Athletics (7-3), 6-1 | Oakland-Alameda County Stadium (0-3) | 4-5 | Lost 3 |
| » W: Matt Keough (3-0) L: Chris Knapp (0-1) | Sixth | 3½ out |
| » Lost to Athletics (8-3), 8-2 | Oakland-Alameda County Stadium (0-4) | 4-6 | Lost 4 |
| » W: Steve McCatty (2-2) L: Frank Tanana (1-1) | Sixth | 3½ out |
| Tuesday, April 22 |
| » Lost to Twins (6-7), 8-1 | Metropolitan Stadium (0-1) | 4-7 | Lost 5 |
| » W: Geoff Zahn (2-1) L: Dave Frost (2-1) | Sixth | 4 out |
| Wednesday, April 23 |
| » Defeated Twins (6-8), 17-0 | Metropolitan Stadium (1-1) | 5-7 | |
| » W: Bruce Kison (1-2) L: Terry Felton (0-2) | Seventh | 4 out |
| Friday, April 25 |
| » Defeated Mariners (8-8), 4-3 | Kingdome (1-0) | 6-7 | Won 2 |
| » W: Don Aase (2-1) L: Mike Parrott (1-3) S: John Montague (2) | Seventh | 3½ out |
| Saturday, April 26 |
| » Defeated Mariners (8-9), 7-6 | Kingdome (2-0) | 7-7 | Won 3 |
| » W: Dave LaRoche (1-0) L: Rob Dressler (0-2) S: Mark Clear (1) | Fifth | 3½ out |
| Sunday, April 27 |
| » Lost to Mariners (9-9), 7-3 | Kingdome (2-1) | 7-8 | |
| » W: Glenn Abbott (2-1) L: Dave Frost (2-2) | Sixth | 3½ out |
| Monday, April 28 |
| » Lost to Athletics (11-7), 8-0 | Anaheim Stadium (4-3) | 7-9 | Lost 2 |
| » W: Rick Langford (2-0) L: Bruce Kison (1-3) | Sixth | 4 out |
| Tuesday, April 29 |
| » Lost to Athletics (12-7), 4-2 | Anaheim Stadium (4-4) | 7-10 | Lost 3 |
| » W: Mike Norris (3-0) L: Frank Tanana (1-2) | Seventh | 4 out |
| Wednesday, April 30 |
| » Defeated Athletics (12-8), 2-1 | Anaheim Stadium (5-4) | 8-10 | |
| » W: Don Aase (3-1) L: Matt Keough (3-2) | Sixth | 4 out |
| Thursday, May 1 |
| » Defeated Mariners (11-11), 2-1 | Anaheim Stadium (6-4) | 9-10 | Won 2 |
| » W: John Montague (1-0) L: Jim Beattie (0-2) | Sixth | 3 out |
| Friday, May 2 |
| » Defeated Mariners (11-12), 3-1 | Anaheim Stadium (7-4) | 10-10 | Won 3 |
| » W: Dave Frost (3-2) L: Glenn Abbott (2-2) | Fourth | 2½ out |
| Saturday, May 3 |
| » Lost to Mariners (12-12), 2-0 | Anaheim Stadium (7-5) | 10-11 | |
| » W: Rick Honeycutt (5-0) L: Bruce Kison (1-4) | Sixth | 3½ out |
| Sunday, May 4 |
| » Defeated Mariners (12-13), 4-3 | Anaheim Stadium (8-5) | 11-11 | |
| » W: Frank Tanana (2-2) L: Floyd Bannister (2-1) S: Mark Clear (2) | Fourth | 3 out |
| Tuesday, May 6 |
| » Lost to Blue Jays (13-9), 3-2 | Anaheim Stadium (8-6) | 11-12 | |
| » W: Dave Lemanczyk (2-3) L: Don Aase (3-2) S: Jerry Garvin (1) | Fifth | 3½ out |
| » Major-league debuts: Stan Cliburn (Angels) |
| Wednesday, May 7 |
| » Lost to Blue Jays (14-9), 7-3 | Anaheim Stadium (8-7) | 11-13 | Lost 2 |
| » W: Dave Stieb (4-1) L: Chris Knapp (0-2) | Sixth | 3½ out |
| Thursday, May 8 |
| » Lost to Blue Jays (15-9), 9-2 | Anaheim Stadium (8-8) | 11-14 | Lost 3 |
| » W: Paul Mirabella (3-1) L: Dave Frost (3-3) | Sixth | 4 out |
| Friday, May 9 |
| » Lost to Tigers (10-16), 6-5 | Anaheim Stadium (8-9) | 11-15 | Lost 4 |
| » W: Aurelio Lopez (1-2) L: John Montague (1-1) | Sixth | 4½ out |
| Saturday, May 10 |
| » Lost to Tigers (11-16), 6-1 | Anaheim Stadium (8-10) | 11-16 | Lost 5 |
| » W: Dan Schatzeder (2-4) L: Frank Tanana (2-3) | Sixth | 5½ out |
| Sunday, May 11 |
| » Lost to Tigers (12-16), 4-0 | Anaheim Stadium (8-11) | 11-17 | Lost 6 |
| » W: Dan Petry (2-0) L: Don Aase (3-3) | Seventh | 6½ out |
| Wednesday, May 14 |
| » Defeated Indians (11-16), 13-7 | Cleveland Stadium (1-0) | 12-17 | |
| » W: Chris Knapp (1-2) L: Dan Spillner (2-2) S: Jim Barr (1) | Sixth | 5 out |
| Friday, May 16 |
| » Defeated Royals (16-15), 11-1 | Royals Stadium (1-0) | 13-17 | Won 2 |
| » W: Bruce Kison (2-4) L: Rich Gale (0-5) | Sixth | 4 out |
| Saturday, May 17 |
| » Lost to Royals (17-15), 2-1 | Royals Stadium (1-1) | 13-18 | |
| » W: Larry Gura (5-2) L: Mark Clear (0-2) | Fifth | 5 out |
| Sunday, May 18 |
| » Lost to Royals (18-15), 5-3 | Royals Stadium (1-2) | 13-19 | Lost 2 |
| » W: Renie Martin (4-1) L: Frank Tanana (2-4) S: Dan Quisenberry (6) | Sixth | 5½ out |
| Monday, May 19 |
| » Defeated Rangers (18-16), 3-2 | Arlington Stadium (1-0) | 14-19 | |
| » W: Mark Clear (1-2) L: Jim Kern (2-4) | Sixth | 5½ out |
| Tuesday, May 20 |
| » Defeated Rangers (18-17), 5-4 | Arlington Stadium (2-0) | 15-19 | Won 2 |
| » W: Alfredo Martinez (1-0) L: Doc Medich (3-2) S: Dave LaRoche (1) | Sixth | 5½ out |
| Wednesday, May 21 |
| » Defeated Rangers (18-18), 9-8 | Arlington Stadium (3-0) | 16-19 | Won 3 |
| » W: Mark Clear (2-2) L: Jim Kern (2-5) | Sixth | 4½ out |
| Thursday, May 22 |
| » Lost to Rangers (19-18), 12-6 | Arlington Stadium (3-1) | 16-20 | |
| » W: Danny Darwin (3-1) L: Don Aase (3-4) | Sixth | 5 out |
| Friday, May 23 |
| » Lost to Royals (22-16), 13-9 | Anaheim Stadium (8-12) | 16-21 | Lost 2 |
| » W: Dennis Leonard (3-4) L: Frank Tanana (2-5) | Sixth | 5½ out |
| Saturday, May 24 |
| » Lost to Royals (23-16), 6-5 | Anaheim Stadium (8-13) | 16-22 | Lost 3 |
| » W: Dan Quisenberry (3-2) L: Mark Clear (2-3) | Sixth | 6½ out |
| Sunday, May 25 |
| » Lost to Royals (24-16), 7-3 | Anaheim Stadium (8-14) | 16-23 | Lost 4 |
| » W: Larry Gura (6-2) L: Dave LaRoche (1-1) | Sixth | 7½ out |
| Monday, May 26 |
| » Lost to Rangers (22-19), 6-5 | Anaheim Stadium (8-15) | 16-24 | Lost 5 |
| » W: Adrian Devine (1-1) L: Mark Clear (2-4) S: Sparky Lyle (4) | Sixth | 7½ out |
| Tuesday, May 27 |
| » Defeated Rangers (22-20), 2-0 | Anaheim Stadium (9-15) | 17-24 | |
| » W: Don Aase (4-4) L: Fergie Jenkins (3-4) | Sixth | 7½ out |
| Wednesday, May 28 |
| » Defeated Rangers (22-21), 7-6 | Anaheim Stadium (10-15) | 18-24 | Won 2 |
| » W: Mark Clear (3-4) L: Jim Kern (2-6) S: Chris Knapp (1) | Sixth | 6½ out |
| Friday, May 30 |
| » Lost to Tigers (19-24), 12-1 | Tiger Stadium (0-1) | 18-25 | |
| » W: Milt Wilcox (3-4) L: Frank Tanana (2-6) | Sixth | 7½ out |
| Saturday, May 31 |
| » Defeated Tigers (19-25), 6-1 | Tiger Stadium (1-1) | 19-25 | |
| » W: Bruce Kison (3-4) L: Pat Underwood (0-3) S: Dave LaRoche (2) | Sixth | 7½ out |
| Monday, June 2 |
| » Defeated Blue Jays (22-23), 6-3 | Exhibition Stadium (1-0) | 20-25 | Won 2 |
| » W: Dave Frost (4-3) L: Luis Leal (1-1) S: Dave LaRoche (3) | Fifth | 6 out |
| Tuesday, June 3 |
| » Lost to Blue Jays (23-23), 7-6 | Exhibition Stadium (1-1) | 20-26 | |
| » W: Joey McLaughlin (2-3) L: Dave LaRoche (1-2) | Sixth | 7 out |
| Wednesday, June 4 |
| » Lost to Blue Jays (24-23), 8-2 | Exhibition Stadium (1-2) | 20-27 | Lost 2 |
| » W: Jim Clancy (4-3) L: Alfredo Martinez (1-1) | Sixth | 8 out |
| Friday, June 6 |
| » Lost to Orioles (24-26), 6-1 | Anaheim Stadium (10-16) | 20-28 | Lost 3 |
| » W: Scott McGregor (5-2) L: Bruce Kison (3-5) | Fifth | 9½ out |
| Saturday, June 7 |
| » Lost to Orioles (25-26), 6-5 | Anaheim Stadium (10-17) | 20-29 | Lost 4 |
| » W: Jim Palmer (5-3) L: Dave Frost (4-4) S: Tim Stoddard (9) | Sixth | 10½ out |
| Sunday, June 8 |
| » Lost to Orioles (26-26), 13-8 | Anaheim Stadium (10-18) | 20-30 | Lost 5 |
| » W: Sammy Stewart (2-5) L: Chris Knapp (1-3) | Seventh | 11½ out |
| Monday, June 9 |
| » Lost to Yankees (33-19), 8-7 | Anaheim Stadium (10-19) | 20-31 | Lost 6 |
| » W: Rich Gossage (1-0) L: Dave Lemanczyk (2-6) | Sixth | 12 out |
| Tuesday, June 10 |
| » Defeated Yankees (33-20), 5-4 | Anaheim Stadium (11-19) | 21-31 | |
| » W: Mark Clear (4-4) L: Rudy May (3-2) | Seventh | 12 out |
| Wednesday, June 11 |
| » Lost to Yankees (34-20), 9-7 | Anaheim Stadium (11-20) | 21-32 | |
| » W: Rich Gossage (2-0) L: Mark Clear (4-5) | Seventh | 12½ out |
| Thursday, June 12 |
| » Lost to Red Sox (28-27), 13-2 | Anaheim Stadium (11-21) | 21-33 | Lost 2 |
| » W: Mike Torrez (2-6) L: Dave Frost (4-5) | Seventh | 13 out |
| Friday, June 13 |
| » Lost to Red Sox (29-27), 3-0 | Anaheim Stadium (11-22) | 21-34 | Lost 3 |
| » W: Dennis Eckersley (2-5) L: Don Aase (4-5) S: Dick Drago (3) | Seventh | 14 out |
| Saturday, June 14 |
| » Lost to Red Sox (30-27), 7-3 | Anaheim Stadium (11-23) | 21-35 | Lost 4 |
| » W: Bob Stanley (5-5) L: Alfredo Martinez (1-2) S: Tom Burgmeier (11) | Seventh | 14 out |
| Sunday, June 15 |
| » Lost to Red Sox (31-27), 6-5 | Anaheim Stadium (11-24) | 21-36 | Lost 5 |
| » W: Steve Renko (4-0) L: Frank Tanana (2-7) S: Skip Lockwood (1) | Seventh | 15 out |
| Monday, June 16 |
| » Lost to Orioles (30-30), 5-2 | Memorial Stadium (0-1) | 21-37 | Lost 6 |
| » W: Jim Palmer (6-3) L: Chris Knapp (1-4) S: Tim Stoddard (10) | Seventh | 15 out |
| Tuesday, June 17 |
| » Lost to Orioles (31-30), 5-3 | Memorial Stadium (0-2) | 21-38 | Lost 7 |
| » W: Steve Stone (8-3) L: Dave Frost (4-6) | Seventh | 16 out |
| Wednesday, June 18 |
| » Lost to Yankees (40-21), 5-0 | Yankee Stadium (0-1) | 21-39 | Lost 8 |
| » W: Ron Guidry (7-3) L: Don Aase (4-6) | Seventh | 17 out |
| Thursday, June 19 |
| » Lost to Yankees (41-21), 7-5 | Yankee Stadium (0-2) | 21-40 | Lost 9 |
| » W: Rudy May (4-2) L: Dave Lemanczyk (2-7) | Seventh | 17 out |
| Friday, June 20 |
| » Defeated Red Sox (34-29), 20-2 | Fenway Park (1-0) | 22-40 | |
| » W: Frank Tanana (3-7) L: Steve Renko (4-1) | Seventh | 16 out |
| Saturday, June 21 |
| » Defeated Red Sox (34-30), 4-2 | Fenway Park (2-0) | 23-40 | Won 2 |
| » W: Chris Knapp (2-4) L: Chuck Rainey (7-3) S: Andy Hassler (1) | Seventh | 15 out |
| Sunday, June 22 |
| » Lost to Red Sox (35-30), 6-3 | Fenway Park (2-1) | 23-41 | |
| » W: Mike Torrez (4-6) L: Jim Barr (0-1) S: Tom Burgmeier (12) | Seventh | 16 out |
| Tuesday, June 24 |
| » Lost to White Sox (31-35), 2-1 | Anaheim Stadium (11-25) | 23-42 | Lost 2 |
| » W: Britt Burns (8-5) L: Don Aase (4-7) S: Ed Farmer (15) | Seventh | 16 out |
| Wednesday, June 25 |
| » Lost to White Sox (32-35), 5-2 | Anaheim Stadium (11-26) | 23-43 | Lost 3 |
| » W: Richard Dotson (7-3) L: Dave Lemanczyk (2-8) S: Ed Farmer (16) | Seventh | 17 out |
| Thursday, June 26 |
| » Lost to White Sox (33-35), 5-2 | Anaheim Stadium (11-27) | 23-44 | Lost 4 |
| » W: Steve Trout (3-7) L: Frank Tanana (3-8) S: Mike Proly (3) | Sixth | 17½ out |
| Friday, June 27 |
| » Defeated Brewers (38-30), 6-5 | Anaheim Stadium (12-27) | 24-44 | |
| » W: Mark Clear (5-5) L: Bill Castro (0-3) | Seventh | 17½ out |
| Saturday, June 28 |
| » Lost to Brewers (39-30), 11-5 | Anaheim Stadium (12-28) | 24-45 | |
| » W: Mike Caldwell (7-4) L: Ed Halicki (0-1) | Seventh | 18½ out |
| Sunday, June 29 |
| » Lost to Brewers (40-30), 5-2 | Anaheim Stadium (12-29) | 24-46 | Lost 2 |
| » W: Reggie Cleveland (6-2) L: Don Aase (4-8) | Sixth | 18½ out |
| Monday, June 30 |
| » Defeated White Sox (35-37), 10-6 | Comiskey Park I (1-0) | 25-46 | |
| » W: Mark Clear (6-5) L: Ed Farmer (5-3) | Sixth | 17½ out |
| Tuesday, July 1 |
| » Defeated White Sox (35-38), 5-2 | Comiskey Park I (2-0) | 26-46 | Won 2 |
| » W: Ed Halicki (1-1) L: Steve Trout (3-8) S: Mark Clear (3) | Seventh | 16½ out |
| Wednesday, July 2 |
| » Lost to White Sox (36-38), 1-0 | Comiskey Park I (2-1) | 26-47 | |
| » W: Ross Baumgarten (2-5) L: Frank Tanana (3-9) | Sixth | 17½ out |
| Thursday, July 3 |
| » Defeated White Sox (36-39), 7-3 | Comiskey Park I (3-1) | 27-47 | |
| » W: Dave Lemanczyk (3-8) L: Rich Wortham (4-4) S: Mark Clear (4) | Sixth | 16½ out |
| Friday, July 4 |
| » Defeated Brewers (42-33), 2-0 | County Stadium (1-0) | 28-47 | Won 2 |
| » W: Don Aase (5-8) L: Reggie Cleveland (6-3) S: Mark Clear (5) | Seventh | 16½ out |
| Saturday, July 5 |
| » Lost to Brewers (43-33), 4-3 | County Stadium (1-1) | 28-48 | |
| » W: Bill Travers (8-3) L: Chris Knapp (2-5) S: John Flinn (2) | Seventh | 17½ out |
| Sunday, July 6 |
| » Defeated Brewers (43-34), 2-0 | County Stadium (2-1) | 29-48 | |
| » W: Ed Halicki (2-1) L: Moose Haas (9-7) S: Mark Clear (6) | Seventh | 16½ out |
| Thursday, July 10 |
| » Defeated Athletics (36-46), 5-1 | Oakland-Alameda County Stadium (1-4) | 30-48 | Won 2 |
| » W: Frank Tanana (4-9) L: Matt Keough (9-9) | Seventh | 17 out |
| » Lost to Athletics (37-46), 5-4 | Oakland-Alameda County Stadium (1-5) | 30-49 | |
| » W: Rick Langford (6-9) L: Don Aase (5-9) | Seventh | 17 out |
| Friday, July 11 |
| » Lost to Athletics (38-46), 6-2 | Oakland-Alameda County Stadium (1-6) | 30-50 | Lost 2 |
| » W: Brian Kingman (5-8) L: Chris Knapp (2-6) S: Jeff Jones (3) | Seventh | 18 out |
| Saturday, July 12 |
| » Lost to Athletics (39-46), 5-4 | Anaheim Stadium (12-30) | 30-51 | Lost 3 |
| » W: Mike Norris (11-6) L: Dave Lemanczyk (3-9) S: Craig Minetto (1) | Sixth | 18 out |
| Sunday, July 13 |
| » Defeated Athletics (39-47), 5-4 | Anaheim Stadium (13-30) | 31-51 | |
| » W: John Montague (2-1) L: Dave Hamilton (0-3) | Fifth | 18 out |
| Monday, July 14 |
| » Lost to Athletics (40-47), 6-4 | Anaheim Stadium (13-31) | 31-52 | |
| » W: Rick Langford (7-9) L: Bruce Kison (3-6) | Sixth | 19 out |
| Tuesday, July 15 |
| » Defeated Indians (39-43), 7-1 | Anaheim Stadium (14-31) | 32-52 | |
| » W: Frank Tanana (5-9) L: John Denny (8-6) | Fifth | 19 out |
| Wednesday, July 16 |
| » Lost to Indians (40-43), 6-2 | Anaheim Stadium (14-32) | 32-53 | |
| » W: Wayne Garland (4-2) L: Don Aase (5-10) | Sixth | 20 out |
| Thursday, July 17 |
| » Lost to Indians (41-43), 5-3 | Anaheim Stadium (14-33) | 32-54 | Lost 2 |
| » W: Len Barker (9-7) L: Chris Knapp (2-7) | Sixth | 20 out |
| Friday, July 18 |
| » Defeated Blue Jays (36-49), 6-3 | Anaheim Stadium (15-33) | 33-54 | |
| » W: Ed Halicki (3-1) L: Jack Kucek (2-2) S: Mark Clear (7) | Sixth | 20 out |
| Saturday, July 19 |
| » Lost to Blue Jays (37-49), 5-4 | Anaheim Stadium (15-34) | 33-55 | |
| » W: Jim Clancy (8-7) L: John Montague (2-2) | Sixth | 20 out |
| Sunday, July 20 |
| » Lost to Blue Jays (38-49), 6-3 | Anaheim Stadium (15-35) | 33-56 | Lost 2 |
| » W: Joey McLaughlin (4-6) L: Mark Clear (6-6) | Seventh | 21 out |
| Monday, July 21 |
| » Lost to Tigers (48-38), 14-3 | Anaheim Stadium (15-36) | 33-57 | Lost 3 |
| » W: Milt Wilcox (9-6) L: Don Aase (5-11) S: Pat Underwood (1) | Seventh | 22 out |
| Tuesday, July 22 |
| » Defeated Tigers (48-39), 6-4 | Anaheim Stadium (16-36) | 34-57 | |
| » W: Andy Hassler (1-0) L: Dave Rozema (5-6) S: Mark Clear (8) | Seventh | 21 out |
| Wednesday, July 23 |
| » Lost to Tigers (49-39), 7-6 | Anaheim Stadium (16-37) | 34-58 | |
| » W: Aurelio Lopez (8-3) L: Mark Clear (6-7) | Seventh | 22 out |
| Future Angel Dallas McPherson is born in Greensboro, NC. |
| Friday, July 25 |
| » Lost to Indians (44-47), 9-8 | Cleveland Stadium (1-1) | 34-59 | Lost 2 |
| » W: Sandy Wihtol (1-0) L: Mark Clear (6-8) | Seventh | 24 out |
| » Lost to Indians (45-47), 10-2 | Cleveland Stadium (1-2) | 34-60 | Lost 3 |
| » W: Ross Grimsley (3-4) L: Alfredo Martinez (1-3) S: Sid Monge (7) | Seventh | 24 out |
| Saturday, July 26 |
| » Lost to Indians (46-47), 14-4 | Cleveland Stadium (1-3) | 34-61 | Lost 4 |
| » W: Wayne Garland (5-3) L: Don Aase (5-12) S: Victor Cruz (4) | Seventh | 24 out |
| Monday, July 28 |
| » Defeated Tigers (51-42), 3-2 | Tiger Stadium (2-1) | 35-61 | |
| » W: John Montague (3-2) L: Dan Petry (5-6) S: Andy Hassler (2) | Seventh | 24 out |
| Tuesday, July 29 |
| » Defeated Tigers (51-43), 7-0 | Tiger Stadium (3-1) | 36-61 | Won 2 |
| » W: Alfredo Martinez (2-3) L: Bruce Robbins (1-2) | Seventh | 24 out |
| Wednesday, July 30 |
| » Defeated Tigers (51-44), 6-5 | Tiger Stadium (4-1) | 37-61 | Won 3 |
| » W: Mark Clear (7-8) L: Dan Schatzeder (6-7) S: Andy Hassler (3) | Seventh | 23 out |
| Thursday, July 31 |
| » Lost to Tigers (52-44), 15-6 | Tiger Stadium (4-2) | 37-62 | |
| » W: Milt Wilcox (11-6) L: Don Aase (5-13) S: Dave Rozema (2) | Seventh | 24 out |
| Friday, August 1 |
| » Lost to Blue Jays (44-55), 9-8 | Exhibition Stadium (1-3) | 37-63 | Lost 2 |
| » W: Jerry Garvin (3-5) L: Mark Clear (7-9) | Seventh | 25 out |
| Saturday, August 2 |
| » Defeated Blue Jays (44-56), 5-4 | Exhibition Stadium (2-3) | 38-63 | |
| » W: Dave LaRoche (2-2) L: Jesse Jefferson (4-7) | Seventh | 25 out |
| Sunday, August 3 |
| » Lost to Blue Jays (45-56), 3-1 | Exhibition Stadium (2-4) | 38-64 | |
| » W: Jim Clancy (10-7) L: Alfredo Martinez (2-4) S: Mike Barlow (1) | Seventh | 25 out |
| Monday, August 4 |
| » Defeated Mariners (39-66), 8-3 | Anaheim Stadium (17-37) | 39-64 | |
| » W: Andy Hassler (2-0) L: Shane Rawley (5-5) | Sixth | 25 out |
| Tuesday, August 5 |
| » Defeated Mariners (39-67), 5-4 | Anaheim Stadium (18-37) | 40-64 | Won 2 |
| » W: Mark Clear (8-9) L: Dave Heaverlo (4-1) | Sixth | 25 out |
| Wednesday, August 6 |
| » Defeated Mariners (39-68), 8-3 | Anaheim Stadium (19-37) | 41-64 | Won 3 |
| » W: John Montague (4-2) L: Rob Dressler (1-6) | Sixth | 25 out |
| Thursday, August 7 |
| » Defeated Twins (47-61), 4-2 | Anaheim Stadium (20-37) | 42-64 | Won 4 |
| » W: Andy Hassler (3-0) L: Albert Williams (1-1) | Sixth | 24½ out |
| Friday, August 8 |
| » Defeated Twins (47-62), 9-5 | Anaheim Stadium (21-37) | 43-64 | Won 5 |
| » W: Dave Lemanczyk (4-9) L: Darrell Jackson (7-7) S: John Montague (3) | Sixth | 25 out |
| Saturday, August 9 |
| » Defeated Twins (47-63), 8-2 | Anaheim Stadium (22-37) | 44-64 | Won 6 |
| » W: Frank Tanana (6-9) L: Geoff Zahn (10-14) | Sixth | 24 out |
| Sunday, August 10 |
| » Lost to Twins (48-63), 5-2 | Anaheim Stadium (22-38) | 44-65 | |
| » W: Jerry Koosman (10-10) L: Jim Barr (0-2) S: Doug Corbett (12) | Sixth | 25 out |
| Tuesday, August 12 |
| » Defeated Mariners (41-71), 9-6 | Kingdome (3-1) | 45-65 | |
| » W: Mark Clear (9-9) L: Dave Heaverlo (5-2) | Sixth | 24½ out |
| Wednesday, August 13 |
| » Defeated Mariners (41-72), 10-4 | Kingdome (4-1) | 46-65 | Won 2 |
| » W: Andy Hassler (4-0) L: Shane Rawley (6-6) | Sixth | 24½ out |
| Thursday, August 14 |
| » Defeated Mariners (41-73), 2-1 | Kingdome (5-1) | 47-65 | Won 3 |
| » W: Alfredo Martinez (3-4) L: Rick Honeycutt (8-13) S: Don Aase (1) | Sixth | 24 out |
| Friday, August 15 |
| » Defeated Twins (49-66), 5-4 | Metropolitan Stadium (2-1) | 48-65 | Won 4 |
| » W: Frank Tanana (7-9) L: Geoff Zahn (10-15) S: Andy Hassler (4) | Fifth | 24 out |
| Sunday, August 17 |
| » Lost to Twins (50-66), 8-1 | Metropolitan Stadium (2-2) | 48-66 | |
| » W: Roger Erickson (4-9) L: Jim Barr (0-3) | Sixth | 26 out |
| » Lost to Twins (51-66), 6-5 | Metropolitan Stadium (2-3) | 48-67 | Lost 2 |
| » W: Jerry Koosman (11-10) L: Chris Knapp (2-8) S: Doug Corbett (13) | Sixth | 26 out |
| Monday, August 18 |
| » Lost to Twins (52-66), 8-3 | Metropolitan Stadium (2-4) | 48-68 | Lost 3 |
| » W: Fernando Arroyo (3-5) L: Dave LaRoche (2-3) | Sixth | 27 out |
| Tuesday, August 19 |
| » Lost to Orioles (69-48), 5-2 | Anaheim Stadium (22-39) | 48-69 | Lost 4 |
| » W: Steve Stone (20-4) L: Alfredo Martinez (3-5) S: Tippy Martinez (9) | Sixth | 28 out |
| Wednesday, August 20 |
| » Lost to Orioles (70-48), 6-5 | Anaheim Stadium (22-40) | 48-70 | Lost 5 |
| » W: Tim Stoddard (3-3) L: Mark Clear (9-10) | Sixth | 29 out |
| Thursday, August 21 |
| » Lost to Orioles (71-48), 7-1 | Anaheim Stadium (22-41) | 48-71 | Lost 6 |
| » W: Scott McGregor (15-6) L: Chris Knapp (2-9) | Sixth | 29 out |
| Friday, August 22 |
| » Defeated Yankees (73-48), 8-4 | Anaheim Stadium (23-41) | 49-71 | |
| » W: Don Aase (6-13) L: Luis Tiant (6-8) S: Andy Hassler (5) | Sixth | 28 out |
| Saturday, August 23 |
| » Lost to Yankees (74-48), 5-2 | Anaheim Stadium (23-42) | 49-72 | |
| » W: Rudy May (11-5) L: Dave LaRoche (2-4) S: Rich Gossage (21) | Sixth | 29 out |
| Sunday, August 24 |
| » Lost to Yankees (75-48), 4-2 | Anaheim Stadium (23-43) | 49-73 | Lost 2 |
| » W: Ron Davis (5-3) L: Alfredo Martinez (3-6) S: Rich Gossage (22) | Sixth | 30 out |
| Monday, August 25 |
| » Lost to Red Sox (65-56), 4-2 | Anaheim Stadium (23-44) | 49-74 | Lost 3 |
| » W: Bob Stanley (9-6) L: Mark Clear (9-11) | Sixth | 31 out |
| Tuesday, August 26 |
| » Lost to Red Sox (66-56), 5-1 | Anaheim Stadium (23-45) | 49-75 | Lost 4 |
| » W: John Tudor (5-2) L: Chris Knapp (2-10) S: Bob Stanley (11) | Sixth | 32 out |
| Thursday, August 28 |
| » Lost to Orioles (75-50), 13-8 | Memorial Stadium (0-3) | 49-76 | Lost 5 |
| » W: Jim Palmer (14-9) L: Dave LaRoche (2-5) | Sixth | 32½ out |
| Friday, August 29 |
| » Defeated Orioles (75-51), 5-0 | Memorial Stadium (1-3) | 50-76 | |
| » W: Alfredo Martinez (4-6) L: Steve Stone (21-5) | Sixth | 32½ out |
| Saturday, August 30 |
| » Defeated Orioles (75-52), 12-6 | Memorial Stadium (2-3) | 51-76 | Won 2 |
| » W: Mark Clear (10-11) L: Mike Flanagan (13-10) | Sixth | 31½ out |
| Sunday, August 31 |
| » Lost to Orioles (76-52), 5-0 | Memorial Stadium (2-4) | 51-77 | |
| » W: Scott McGregor (16-7) L: Chris Knapp (2-11) | Sixth | 32½ out |
| Monday, September 1 |
| » Lost to Red Sox (71-56), 4-3 | Fenway Park (2-2) | 51-78 | Lost 2 |
| » W: Dick Drago (5-5) L: Dave Frost (4-7) S: Tom Burgmeier (20) | Sixth | 32½ out |
| Tuesday, September 2 |
| » Lost to Red Sox (72-56), 10-2 | Fenway Park (2-3) | 51-79 | Lost 3 |
| » W: Steve Renko (9-5) L: Jim Dorsey (0-1) | Sixth | 33 out |
| » Major-league debuts: Steve Crawford and Chico Walker (Red Sox) Jim Dorsey (Angels) |
| Wednesday, September 3 |
| » Defeated Red Sox (72-57), 7-2 | Fenway Park (3-3) | 52-79 | |
| » W: Alfredo Martinez (5-6) L: Mike Torrez (8-13) | Sixth | 32 out |
| Thursday, September 4 |
| » Lost to Yankees (82-51), 5-3 | Yankee Stadium (0-3) | 52-80 | |
| » W: Gaylord Perry (9-10) L: Frank Tanana (7-10) S: Ron Guidry (1) | Sixth | 32 out |
| Friday, September 5 |
| » Lost to Yankees (83-51), 6-5 | Yankee Stadium (0-4) | 52-81 | Lost 2 |
| » W: Rich Gossage (6-1) L: Andy Hassler (4-1) | Sixth | 33 out |
| Saturday, September 6 |
| » Lost to Yankees (84-51), 7-4 | Yankee Stadium (0-5) | 52-82 | Lost 3 |
| » W: Tom Underwood (12-9) L: Dave Frost (4-8) S: Rich Gossage (23) | Sixth | 33 out |
| Sunday, September 7 |
| » Lost to Yankees (85-51), 4-1 | Yankee Stadium (0-6) | 52-83 | Lost 4 |
| » W: Rudy May (13-5) L: Jim Dorsey (0-2) S: Rich Gossage (24) | Sixth | 34 out |
| Monday, September 8 |
| » Defeated Royals (87-51), 7-4 | Anaheim Stadium (24-45) | 53-83 | |
| » W: Don Aase (7-13) L: Larry Gura (18-6) S: Andy Hassler (6) | Sixth | 33 out |
| Tuesday, September 9 |
| » Defeated Royals (87-52), 4-3 | Anaheim Stadium (25-45) | 54-83 | Won 2 |
| » W: Frank Tanana (8-10) L: Paul Splittorff (11-10) S: Mark Clear (9) | Sixth | 32 out |
| Wednesday, September 10 |
| » Defeated Royals (87-53), 8-3 | Anaheim Stadium (26-45) | 55-83 | Won 3 |
| » W: Don Aase (8-13) L: Renie Martin (8-9) S: Andy Hassler (7) | Sixth | 31 out |
| Thursday, September 11 |
| » Lost to Royals (88-53), 7-2 | Anaheim Stadium (26-46) | 55-84 | |
| » W: Dennis Leonard (18-9) L: Bob Ferris (0-1) | Sixth | 32 out |
| Friday, September 12 |
| » Defeated Rangers (69-71), 8-4 | Anaheim Stadium (27-46) | 56-84 | |
| » W: Jim Dorsey (1-2) L: Doc Medich (12-10) S: Dave LaRoche (4) | Sixth | 31 out |
| Saturday, September 13 |
| » Defeated Rangers (69-72), 10-1 | Anaheim Stadium (28-46) | 57-84 | Won 2 |
| » W: Alfredo Martinez (6-6) L: John Butcher (1-1) | Sixth | 30 out |
| Sunday, September 14 |
| » Defeated Rangers (69-73), 3-1 | Anaheim Stadium (29-46) | 58-84 | Won 3 |
| » W: Frank Tanana (9-10) L: Ken Clay (2-2) S: Andy Hassler (8) | Sixth | 30 out |
| Monday, September 15 |
| » Major-league debuts: Andy Rincon (Cardinals) |
| Wednesday, September 17 |
| » Lost to Royals (90-55), 5-0 | Royals Stadium (1-3) | 58-85 | |
| » W: Dennis Leonard (19-9) L: Ralph Botting (0-1) | Sixth | 30 out |
| » Defeated Royals (90-56), 7-4 | Royals Stadium (2-3) | 59-85 | |
| » W: Dave LaRoche (3-5) L: Larry Gura (18-8) S: Andy Hassler (9) | Sixth | 30 out |
| Thursday, September 18 |
| » Lost to Royals (91-56), 5-2 | Royals Stadium (2-4) | 59-86 | |
| » W: Renie Martin (9-9) L: Alfredo Martinez (6-7) | Sixth | 31 out |
| Friday, September 19 |
| » Defeated Rangers (71-76), 6-2 | Arlington Stadium (4-1) | 60-86 | |
| » W: Frank Tanana (10-10) L: Jon Matlack (10-8) | Sixth | 31 out |
| Saturday, September 20 |
| » Defeated Rangers (71-77), 6-4 | Arlington Stadium (5-1) | 61-86 | Won 2 |
| » W: Andy Hassler (5-1) L: Charlie Hough (3-5) | Sixth | 30 out |
| Sunday, September 21 |
| » Defeated Rangers (71-78), 9-2 | Arlington Stadium (6-1) | 62-86 | Won 3 |
| » W: Jim Barr (1-3) L: Doc Medich (12-11) S: Don Aase (2) | Fifth | 29 out |
| Monday, September 22 |
| » Defeated Brewers (81-71), 7-3 | County Stadium (3-1) | 63-86 | Won 4 |
| » W: Mark Clear (11-11) L: Bob McClure (4-8) | Fifth | 28 out |
| Tuesday, September 23 |
| » Defeated Brewers (81-72), 2-1 | County Stadium (4-1) | 64-86 | Won 5 |
| » W: Alfredo Martinez (7-7) L: Mike Caldwell (13-11) S: Andy Hassler (10) | Fifth | 27 out |
| Wednesday, September 24 |
| » Lost to Brewers (82-72), 6-0 | County Stadium (4-2) | 64-87 | |
| » W: Lary Sorensen (12-9) L: Frank Tanana (10-11) | Fifth | 27 out |
| Friday, September 26 |
| » Lost to White Sox (64-88), 5-4 | Anaheim Stadium (29-47) | 64-88 | Lost 2 |
| » W: Dewey Robinson (1-1) L: Jim Barr (1-4) S: Ed Farmer (29) | Fifth | 27 out |
| Saturday, September 27 |
| » Lost to White Sox (65-88), 6-3 | Anaheim Stadium (29-48) | 64-89 | Lost 3 |
| » W: Richard Dotson (12-10) L: Ralph Botting (0-2) | Sixth | 27 out |
| Sunday, September 28 |
| » Lost to White Sox (66-88), 8-1 | Anaheim Stadium (29-49) | 64-90 | Lost 4 |
| » W: Britt Burns (14-13) L: Alfredo Martinez (7-8) | Sixth | 27 out |
| Monday, September 29 |
| » Defeated Brewers (83-75), 6-2 | Anaheim Stadi |