| Wednesday, January 3 |
| Future Twin Michael Restovich is born in Rochester, MN. |
| Tuesday, January 23 |
| Future Twin Juan Rincon is born in Maracaibo, Venezuela. |
| Tuesday, March 13 |
| Future Twin Johan Santana is born in Tovar Merida, Venezuela. |
| Tuesday, March 27 |
| Future Twin Michael Cuddyer is born in Norfolk, VA. |
| Wednesday, April 4 |
| » Major-league debuts: Mark Clear (Angels) |
| Friday, April 6 |
| » Defeated Athletics (0-1), 5-3 | Oakland-Alameda County Stadium (1-0) | 1-0 | |
| » W: Dave Goltz (1-0) L: Rick Langford (0-1) S: Mike Marshall (1) | Second | ½ out |
| » Major-league debuts: John Castino and Rick Sofield (Twins) |
| Saturday, April 7 |
| » Defeated Athletics (0-2), 3-1 | Oakland-Alameda County Stadium (2-0) | 2-0 | Won 2 |
| » W: Mike Marshall (1-0) L: Jim Todd (0-1) | First | -- |
| Sunday, April 8 |
| » Defeated Athletics (0-3), 3-1 | Oakland-Alameda County Stadium (3-0) | 3-0 | Won 3 |
| » W: Geoff Zahn (1-0) L: Mike Norris (0-1) | First | -- |
| Tuesday, April 10 |
| » Defeated Angels (2-3), 8-1 | Anaheim Stadium (1-0) | 4-0 | Won 4 |
| » W: Jerry Koosman (1-0) L: Frank Tanana (0-2) S: Mike Marshall (2) | First | -- |
| Wednesday, April 11 |
| » Lost to Angels (3-3), 11-2 | Anaheim Stadium (1-1) | 4-1 | |
| » W: Nolan Ryan (1-1) L: Dave Goltz (1-1) | Second | 1 out |
| Thursday, April 12 |
| » Lost to Angels (4-3), 7-1 | Anaheim Stadium (1-2) | 4-2 | Lost 2 |
| » W: Chris Knapp (1-0) L: Roger Erickson (0-1) | Third | 1 out |
| Friday, April 13 |
| » Defeated Mariners (5-4), 8-2 | Kingdome (1-0) | 5-2 | |
| » W: Geoff Zahn (2-0) L: Paul Mitchell (0-1) S: Mike Marshall (3) | Second | 1 out |
| Saturday, April 14 |
| » Defeated Mariners (5-5), 6-5 | Kingdome (2-0) | 6-2 | Won 2 |
| » W: Mike Marshall (2-0) L: Floyd Bannister (1-1) | Second | 1 out |
| Sunday, April 15 |
| » Defeated Mariners (5-6), 18-6 | Kingdome (3-0) | 7-2 | Won 3 |
| » W: Jerry Koosman (2-0) L: Glenn Abbott (1-1) | Second | 1 out |
| Tuesday, April 17 |
| » Lost to Angels (8-3), 6-0 | Metropolitan Stadium (0-1) | 7-3 | |
| » W: Nolan Ryan (2-1) L: Dave Goltz (1-2) | Third | 1 out |
| Wednesday, April 18 |
| » Lost to Angels (9-3), 11-6 | Metropolitan Stadium (0-2) | 7-4 | Lost 2 |
| » W: Dyar Miller (1-0) L: Roger Erickson (0-2) S: Mark Clear (1) | Third | 1 out |
| Thursday, April 19 |
| » Lost to Angels (10-3), 6-4 | Metropolitan Stadium (0-3) | 7-5 | Lost 3 |
| » W: Don Aase (2-0) L: Mike Marshall (2-1) S: Dave LaRoche (2) | Third | 1½ out |
| Saturday, April 21 |
| » Defeated Mariners (5-10), 6-5 | Metropolitan Stadium (1-3) | 8-5 | |
| » W: Jerry Koosman (3-0) L: Floyd Bannister (1-2) S: Mike Marshall (4) | Third | 3 out |
| Future Twin Terry Tiffee is born in North Little Rock, AR. |
| Sunday, April 22 |
| » Defeated Mariners (5-11), 3-1 | Metropolitan Stadium (2-3) | 9-5 | Won 2 |
| » W: Dave Goltz (2-2) L: Glenn Abbott (1-2) | Third | 2 out |
| Tuesday, April 24 |
| » Lost to Indians (5-9), 7-2 | Cleveland Stadium (0-1) | 9-6 | |
| » W: Rick Wise (2-2) L: Roger Erickson (0-3) | Third | 2 out |
| Wednesday, April 25 |
| » Defeated Indians (5-10), 4-2 | Cleveland Stadium (1-1) | 10-6 | |
| » W: Pete Redfern (1-0) L: Sid Monge (1-1) S: Mike Marshall (5) | Third | 1 out |
| Friday, April 27 |
| » Defeated Tigers (6-8), 5-3 | Tiger Stadium (1-0) | 11-6 | Won 2 |
| » W: Jerry Koosman (4-0) L: Dave Rozema (1-2) S: Mike Marshall (6) | Second | 1½ out |
| Saturday, April 28 |
| » Lost to Tigers (7-8), 5-3 | Tiger Stadium (1-1) | 11-7 | |
| » W: Kip Young (1-0) L: Dave Goltz (2-3) S: John Hiller (2) | Second | 1½ out |
| Sunday, April 29 |
| » Defeated Tigers (7-9), 5-3 | Tiger Stadium (2-1) | 12-7 | |
| » W: Geoff Zahn (3-0) L: Milt Wilcox (2-1) S: Mike Marshall (7) | Second | 1½ out |
| Monday, April 30 |
| » Defeated Blue Jays (7-15), 6-3 | Exhibition Stadium (1-0) | 13-7 | Won 2 |
| » W: Paul Hartzell (1-0) L: Mark Lemongello (0-3) | Second | 1½ out |
| Tuesday, May 1 |
| » Defeated Blue Jays (7-16), 3-2 | Exhibition Stadium (2-0) | 14-7 | Won 3 |
| » W: Jerry Koosman (5-0) L: Jesse Jefferson (0-2) S: Mike Marshall (8) | First | -- |
| Wednesday, May 2 |
| » Defeated Blue Jays (7-17), 7-5 | Exhibition Stadium (3-0) | 15-7 | Won 4 |
| » W: Dave Goltz (3-3) L: Phil Huffman (2-2) S: Mike Marshall (9) | First | -- |
| Thursday, May 3 |
| » Defeated Tigers (8-10), 7-6 | Metropolitan Stadium (3-3) | 16-7 | Won 5 |
| » W: Mike Marshall (3-1) L: Jack Billingham (1-3) | First | -- |
| Friday, May 4 |
| » Defeated Tigers (8-11), 7-6 | Metropolitan Stadium (4-3) | 17-7 | Won 6 |
| » W: Mike Marshall (4-1) L: Aurelio Lopez (0-1) | First | -- |
| Saturday, May 5 |
| » Lost to Tigers (9-11), 8-4 | Metropolitan Stadium (4-4) | 17-8 | |
| » W: Jack Billingham (2-3) L: Paul Hartzell (1-1) | First | -- |
| Sunday, May 6 |
| » Defeated Tigers (9-12), 9-6 | Metropolitan Stadium (5-4) | 18-8 | |
| » W: Mike Marshall (5-1) L: John Hiller (1-1) | First | -- |
| Monday, May 7 |
| » Defeated Blue Jays (8-21), 6-1 | Metropolitan Stadium (6-4) | 19-8 | Won 2 |
| » W: Dave Goltz (4-3) L: Phil Huffman (2-3) | First | -- |
| Tuesday, May 8 |
| » Defeated Blue Jays (8-22), 16-6 | Metropolitan Stadium (7-4) | 20-8 | Won 3 |
| » W: Mike Bacsik (1-0) L: Mike Willis (0-2) | First | -- |
| Friday, May 11 |
| » Defeated Indians (10-19), 4-3 | Metropolitan Stadium (8-4) | 21-8 | Won 4 |
| » W: Mike Marshall (6-1) L: Sid Monge (1-3) | First | -- |
| Saturday, May 12 |
| » Defeated Indians (10-20), 4-0 | Metropolitan Stadium (9-4) | 22-8 | Won 5 |
| » W: Jerry Koosman (6-0) L: Mike Paxton (2-2) | First | -- |
| Sunday, May 13 |
| » Lost to Indians (11-20), 3-2 | Metropolitan Stadium (9-5) | 22-9 | |
| » W: Wayne Garland (1-4) L: Dave Goltz (4-4) S: Victor Cruz (2) | First | -- |
| Monday, May 14 |
| » Lost to Rangers (19-14), 7-5 | Metropolitan Stadium (9-6) | 22-10 | Lost 2 |
| » W: Jim Kern (5-0) L: Mike Marshall (6-2) | First | -- |
| Tuesday, May 15 |
| » Lost to Rangers (20-14), 9-8 | Metropolitan Stadium (9-7) | 22-11 | Lost 3 |
| » W: Sparky Lyle (3-2) L: Mike Marshall (6-3) S: Jim Kern (4) | First | -- |
| Wednesday, May 16 |
| » Lost to Rangers (21-14), 8-4 | Metropolitan Stadium (9-8) | 22-12 | Lost 4 |
| » W: Jon Matlack (2-2) L: Paul Hartzell (1-2) S: Jim Kern (5) | First | -- |
| Thursday, May 17 |
| » Defeated Royals (21-17), 7-6 | Royals Stadium (1-0) | 23-12 | |
| » W: Jerry Koosman (7-0) L: Dennis Leonard (3-4) S: Mike Marshall (10) | First | -- |
| Friday, May 18 |
| » Defeated Royals (21-18), 10-6 | Royals Stadium (2-0) | 24-12 | Won 2 |
| » W: Mike Marshall (7-3) L: Renie Martin (0-1) | First | -- |
| Sunday, May 20 |
| » Lost to Royals (22-18), 5-1 | Royals Stadium (2-1) | 24-13 | |
| » W: Paul Splittorff (6-3) L: Roger Erickson (0-4) | First | -- |
| Monday, May 21 |
| » Defeated Rangers (22-17), 7-6 | Arlington Stadium (1-0) | 25-13 | |
| » W: Pete Redfern (2-0) L: Sparky Lyle (3-3) S: Mike Marshall (11) | First | -- |
| Tuesday, May 22 |
| » Lost to Rangers (23-17), 4-3 | Arlington Stadium (1-1) | 25-14 | |
| » W: Jim Kern (6-0) L: Jerry Koosman (7-1) | First | -- |
| Wednesday, May 23 |
| » Lost to Rangers (24-17), 7-2 | Arlington Stadium (1-2) | 25-15 | Lost 2 |
| » W: Fergie Jenkins (5-2) L: Dave Goltz (4-5) | First | -- |
| Friday, May 25 |
| » Lost to Royals (24-20), 4-3 | Metropolitan Stadium (9-9) | 25-16 | Lost 3 |
| » W: Paul Splittorff (7-3) L: Mike Marshall (7-4) S: Al Hrabosky (5) | First | -- |
| Saturday, May 26 |
| » Lost to Royals (25-20), 7-4 | Metropolitan Stadium (9-10) | 25-17 | Lost 4 |
| » W: Rich Gale (4-3) L: Paul Hartzell (1-3) S: Al Hrabosky (6) | First | -- |
| Sunday, May 27 |
| » Lost to Royals (26-20), 2-1 | Metropolitan Stadium (9-11) | 25-18 | Lost 5 |
| » W: Steve Busby (2-2) L: Jerry Koosman (7-2) | Second | 2 out |
| Monday, May 28 |
| » Defeated Athletics (16-32), 10-7 | Metropolitan Stadium (10-11) | 26-18 | |
| » W: Mike Marshall (8-4) L: Dave Heaverlo (2-4) | Second | 1½ out |
| Wednesday, May 30 |
| » Lost to Athletics (17-32), 5-4 | Metropolitan Stadium (10-12) | 26-19 | |
| » W: John Henry Johnson (2-7) L: Roger Erickson (0-5) S: Bob Lacey (4) | Third | 2 out |
| Thursday, May 31 |
| » Defeated Athletics (17-33), 13-2 | Metropolitan Stadium (11-12) | 27-19 | |
| » W: Paul Hartzell (2-3) L: Rick Langford (1-8) | Second | 2 out |
| Friday, June 1 |
| » Lost to Red Sox (28-19), 5-2 | Metropolitan Stadium (11-13) | 27-20 | |
| » W: Bob Stanley (5-3) L: Jerry Koosman (7-3) S: Bill Campbell (4) | Third | 1 out |
| Saturday, June 2 |
| » Defeated Red Sox (28-20), 8-2 | Metropolitan Stadium (12-13) | 28-20 | |
| » W: Dave Goltz (5-5) L: Chuck Rainey (3-3) | Second | 2 out |
| Sunday, June 3 |
| » Lost to Red Sox (29-20), 8-2 | Metropolitan Stadium (12-14) | 28-21 | |
| » W: Steve Renko (4-2) L: Geoff Zahn (3-1) S: Bill Campbell (5) | Fourth | 1 out |
| Monday, June 4 |
| » Lost to Orioles (32-20), 3-2 | Memorial Stadium (0-1) | 28-22 | Lost 2 |
| » W: Don Stanhouse (4-1) L: Mike Marshall (8-5) | Fourth | 2 out |
| Tuesday, June 5 |
| » Defeated Orioles (32-21), 3-1 | Memorial Stadium (1-1) | 29-22 | |
| » W: Paul Hartzell (3-3) L: Steve Stone (3-5) S: Mike Marshall (12) | Third | 2 out |
| Wednesday, June 6 |
| » Lost to Yankees (30-25), 3-2 | Yankee Stadium (0-1) | 29-23 | |
| » W: Ron Guidry (6-4) L: Jerry Koosman (7-4) | Third | 2 out |
| » Major-league debuts: Darryl Jones (Yankees) |
| Thursday, June 7 |
| » Defeated Yankees (30-26), 4-1 | Yankee Stadium (1-1) | 30-23 | |
| » W: Geoff Zahn (4-1) L: Jim Beattie (3-3) S: Mike Marshall (13) | Second | 1½ out |
| Friday, June 8 |
| » Lost to Red Sox (33-21), 2-1 | Fenway Park (0-1) | 30-24 | |
| » W: Bob Stanley (6-4) L: Dave Goltz (5-6) | Second | 2½ out |
| Saturday, June 9 |
| » Lost to Red Sox (34-21), 12-6 | Fenway Park (0-2) | 30-25 | Lost 2 |
| » W: Mike Torrez (6-3) L: Roger Erickson (0-6) | Third | 3½ out |
| Sunday, June 10 |
| » Lost to Red Sox (35-21), 5-0 | Fenway Park (0-3) | 30-26 | Lost 3 |
| » W: Dennis Eckersley (6-3) L: Paul Hartzell (3-4) | Third | 3½ out |
| Tuesday, June 12 |
| » Lost to Yankees (33-27), 4-1 | Metropolitan Stadium (12-15) | 30-27 | Lost 4 |
| » W: Ron Davis (4-0) L: Jerry Koosman (7-5) | Fourth | 4 out |
| Wednesday, June 13 |
| » Defeated Yankees (33-28), 8-7 | Metropolitan Stadium (13-15) | 31-27 | |
| » W: Pete Redfern (3-0) L: Ray Burris (1-2) S: Mike Marshall (14) | Second | 3½ out |
| Thursday, June 14 |
| » Defeated Yankees (33-29), 4-2 | Metropolitan Stadium (14-15) | 32-27 | Won 2 |
| » W: Geoff Zahn (5-1) L: Tommy John (10-2) S: Mike Marshall (15) | Second | 3½ out |
| Friday, June 15 |
| » Lost to Orioles (40-22), 6-5 | Metropolitan Stadium (14-16) | 32-28 | |
| » W: Don Stanhouse (5-1) L: Mike Marshall (8-6) S: Tim Stoddard (2) | Third | 4½ out |
| » Major-league debuts: Wayne Krenchicki (Orioles) |
| Sunday, June 17 |
| » Lost to Orioles (41-22), 8-5 | Metropolitan Stadium (14-17) | 32-29 | Lost 2 |
| » W: Mike Flanagan (8-5) L: Jerry Koosman (7-6) S: Tim Stoddard (3) | Third | 5 out |
| Tuesday, June 19 |
| » Lost to Brewers (37-30), 10-9 | County Stadium (0-1) | 32-30 | Lost 3 |
| » W: Bob McClure (4-1) L: Mike Bacsik (1-1) S: Jerry Augustine (3) | Fourth | 5½ out |
| Wednesday, June 20 |
| » Lost to Brewers (38-30), 8-3 | County Stadium (0-2) | 32-31 | Lost 4 |
| » W: Bill Travers (5-3) L: Paul Hartzell (3-5) | Fourth | 6½ out |
| Thursday, June 21 |
| » Lost to Brewers (39-30), 3-2 | County Stadium (0-3) | 32-32 | Lost 5 |
| » W: Mike Caldwell (7-5) L: Gary Serum (0-1) | Fourth | 6½ out |
| Friday, June 22 |
| » Defeated White Sox (32-36), 5-3 | Comiskey Park I (1-0) | 33-32 | |
| » W: Geoff Zahn (6-1) L: Ken Kravec (8-5) S: Mike Marshall (16) | Fourth | 5½ out |
| Saturday, June 23 |
| » Defeated White Sox (32-37), 6-1 | Comiskey Park I (2-0) | 34-32 | Won 2 |
| » W: Dave Goltz (6-6) L: Ross Baumgarten (5-5) | Fourth | 4½ out |
| Sunday, June 24 |
| » Defeated White Sox (32-38), 4-3 | Comiskey Park I (3-0) | 35-32 | Won 3 |
| » W: Mike Bacsik (2-1) L: Rich Wortham (7-7) | Third | 3 out |
| » Defeated White Sox (32-39), 7-1 | Comiskey Park I (4-0) | 36-32 | Won 4 |
| » W: Jerry Koosman (8-6) L: Ed Farmer (2-2) | Third | 3 out |
| Tuesday, June 26 |
| » Defeated Brewers (41-32), 8-7 | Metropolitan Stadium (15-17) | 37-32 | Won 5 |
| » W: Mike Marshall (9-6) L: Jerry Augustine (3-3) | Third | 3 out |
| Wednesday, June 27 |
| » Lost to Brewers (42-32), 9-8 | Metropolitan Stadium (15-18) | 37-33 | |
| » W: Mike Caldwell (8-5) L: Gary Serum (0-2) S: Jerry Augustine (4) | Third | 2 out |
| Thursday, June 28 |
| » Lost to Brewers (43-32), 6-5 | Metropolitan Stadium (15-19) | 37-34 | Lost 2 |
| » W: Bill Castro (2-0) L: Mike Marshall (9-7) | Third | 3 out |
| Friday, June 29 |
| » Defeated White Sox (33-42), 5-2 | Metropolitan Stadium (16-19) | 38-34 | |
| » W: Jerry Koosman (9-6) L: Rich Wortham (7-8) | Fourth | 3 out |
| Saturday, June 30 |
| » Defeated White Sox (33-43), 16-4 | Metropolitan Stadium (17-19) | 39-34 | Won 2 |
| » W: Geoff Zahn (7-1) L: Ed Farmer (2-3) | Fourth | 3 out |
| Sunday, July 1 |
| » Defeated White Sox (33-44), 2-1 | Metropolitan Stadium (18-19) | 40-34 | Won 3 |
| » W: Paul Hartzell (4-5) L: Fred Howard (1-3) | Third | 2 out |
| Monday, July 2 |
| » Defeated Mariners (34-47), 7-0 | Metropolitan Stadium (19-19) | 41-34 | Won 4 |
| » W: Darrell Jackson (1-0) L: Odell Jones (2-8) | Third | 2 out |
| Tuesday, July 3 |
| » Defeated Mariners (34-48), 12-2 | Metropolitan Stadium (20-19) | 42-34 | Won 5 |
| » W: Pete Redfern (4-0) L: Mike Parrott (6-4) | Third | 2½ out |
| » Lost to Mariners (35-48), 10-2 | Metropolitan Stadium (20-20) | 42-35 | |
| » W: Byron McLaughlin (5-2) L: Gary Serum (0-3) | Third | 2½ out |
| Wednesday, July 4 |
| » Defeated Mariners (35-49), 7-2 | Metropolitan Stadium (21-20) | 43-35 | |
| » W: Jerry Koosman (10-6) L: Glenn Abbott (4-9) | Third | 2½ out |
| Thursday, July 5 |
| » Lost to Mariners (36-49), 4-0 | Metropolitan Stadium (21-21) | 43-36 | |
| » W: Rick Honeycutt (5-5) L: Geoff Zahn (7-2) | Third | 3 out |
| Friday, July 6 |
| » Lost to Indians (37-44), 6-5 | Cleveland Stadium (1-2) | 43-37 | Lost 2 |
| » W: Dan Spillner (2-2) L: Paul Hartzell (4-6) S: Sid Monge (9) | Third | 3½ out |
| Saturday, July 7 |
| » Lost to Indians (38-44), 9-3 | Cleveland Stadium (1-3) | 43-38 | Lost 3 |
| » W: Mike Paxton (5-4) L: Darrell Jackson (1-1) | Third | 4½ out |
| Sunday, July 8 |
| » Lost to Indians (39-44), 5-4 | Cleveland Stadium (1-4) | 43-39 | Lost 4 |
| » W: Victor Cruz (2-6) L: Mike Marshall (9-8) | Third | 4½ out |
| » Defeated Indians (39-45), 7-2 | Cleveland Stadium (2-4) | 44-39 | |
| » W: Dave Goltz (7-6) L: Rick Waits (9-8) | Third | 4½ out |
| Monday, July 9 |
| » Defeated Tigers (40-43), 5-3 | Tiger Stadium (3-1) | 45-39 | Won 2 |
| » W: Jerry Koosman (11-6) L: Steve Baker (1-5) S: Mike Marshall (17) | Third | 4 out |
| Tuesday, July 10 |
| » Lost to Tigers (41-43), 6-5 | Tiger Stadium (3-2) | 45-40 | |
| » W: Aurelio Lopez (4-2) L: Mike Marshall (9-9) | Third | 5 out |
| Wednesday, July 11 |
| » Defeated Tigers (41-44), 3-0 | Tiger Stadium (4-2) | 46-40 | |
| » W: Darrell Jackson (2-1) L: Jack Morris (7-5) S: Pete Redfern (1) | Third | 4 out |
| Friday, July 13 |
| » Defeated Blue Jays (28-63), 6-4 | Exhibition Stadium (4-0) | 47-40 | Won 2 |
| » W: Dave Goltz (8-6) L: Dave Lemanczyk (7-7) S: Mike Marshall (18) | Third | 4 out |
| Saturday, July 14 |
| » Lost to Blue Jays (29-63), 4-2 | Exhibition Stadium (4-1) | 47-41 | |
| » W: Dave Stieb (2-1) L: Jerry Koosman (11-7) | Third | 5 out |
| Sunday, July 15 |
| » Defeated Blue Jays (29-64), 9-4 | Exhibition Stadium (5-1) | 48-41 | |
| » W: Geoff Zahn (8-2) L: Jim Clancy (2-6) | Third | 5 out |
| Thursday, July 19 |
| » Lost to Tigers (45-45), 8-3 | Metropolitan Stadium (21-22) | 48-42 | |
| » W: Pat Underwood (5-0) L: Jerry Koosman (11-8) | Third | 5½ out |
| Friday, July 20 |
| » Defeated Tigers (45-46), 14-6 | Metropolitan Stadium (22-22) | 49-42 | |
| » W: Gary Serum (1-3) L: Kip Young (2-2) | Third | 4½ out |
| Saturday, July 21 |
| » Defeated Blue Jays (29-67), 6-4 | Metropolitan Stadium (23-22) | 50-42 | Won 2 |
| » W: Dave Goltz (9-6) L: Phil Huffman (4-11) S: Mike Marshall (19) | Third | 3 out |
| » Defeated Blue Jays (29-68), 4-3 | Metropolitan Stadium (24-22) | 51-42 | Won 3 |
| » W: Paul Hartzell (5-6) L: Balor Moore (2-2) | Third | 3 out |
| Sunday, July 22 |
| » Defeated Blue Jays (29-69), 13-1 | Metropolitan Stadium (25-22) | 52-42 | Won 4 |
| » W: Pete Redfern (5-0) L: Dave Lemanczyk (7-8) | Second | 2 out |
| Monday, July 23 |
| » Defeated Blue Jays (29-70), 7-6 | Metropolitan Stadium (26-22) | 53-42 | Won 5 |
| » W: Mike Marshall (10-9) L: Mark Lemongello (1-9) | Second | 2 out |
| Tuesday, July 24 |
| » Lost to Indians (45-52), 4-2 | Metropolitan Stadium (26-23) | 53-43 | |
| » W: Rick Wise (10-5) L: Jerry Koosman (11-9) | Second | 2 out |
| Wednesday, July 25 |
| » Lost to Indians (46-52), 2-0 | Metropolitan Stadium (26-24) | 53-44 | Lost 2 |
| » W: Rick Waits (10-9) L: Dave Goltz (9-7) | Second | 3 out |
| Thursday, July 26 |
| » Lost to Indians (47-52), 7-2 | Metropolitan Stadium (26-25) | 53-45 | Lost 3 |
| » W: Dan Spillner (5-2) L: Pete Redfern (5-1) S: Sid Monge (12) | Second | 3 out |
| Friday, July 27 |
| » Defeated Angels (58-45), 3-1 | Anaheim Stadium (2-2) | 54-45 | |
| » W: Geoff Zahn (9-2) L: Dave Frost (8-7) S: Mike Marshall (20) | Second | 2 out |
| Saturday, July 28 |
| » Lost to Angels (59-45), 5-0 | Anaheim Stadium (2-3) | 54-46 | |
| » W: Don Aase (8-7) L: Jerry Koosman (11-10) | Second | 3 out |
| Sunday, July 29 |
| » Lost to Angels (60-45), 9-3 | Anaheim Stadium (2-4) | 54-47 | Lost 2 |
| » W: Steve Eddy (1-0) L: Darrell Jackson (2-2) S: Dave LaRoche (9) | Second | 4 out |
| Monday, July 30 |
| » Defeated Athletics (29-77), 3-0 | Oakland-Alameda County Stadium (4-0) | 55-47 | |
| » W: Dave Goltz (10-7) L: Brian Kingman (1-4) | Second | 3 out |
| Tuesday, July 31 |
| » Lost to Athletics (30-77), 2-1 | Oakland-Alameda County Stadium (4-1) | 55-48 | |
| » W: Steve McCatty (7-5) L: Geoff Zahn (9-3) | Second | 4 out |
| Wednesday, August 1 |
| » Lost to Athletics (31-77), 7-1 | Oakland-Alameda County Stadium (4-2) | 55-49 | Lost 2 |
| » W: Rick Langford (6-12) L: Paul Hartzell (5-7) | Third | 4 out |
| Friday, August 3 |
| » Defeated Angels (61-48), 4-1 | Metropolitan Stadium (27-25) | 56-49 | |
| » W: Jerry Koosman (12-10) L: Jim Barr (7-8) S: Mike Marshall (21) | Third | 3 out |
| Saturday, August 4 |
| » Lost to Angels (62-48), 7-1 | Metropolitan Stadium (27-26) | 56-50 | |
| » W: Dave Frost (10-7) L: Dave Goltz (10-8) S: Mark Clear (10) | Third | 4 out |
| Sunday, August 5 |
| » Lost to Angels (63-48), 11-7 | Metropolitan Stadium (27-27) | 56-51 | Lost 2 |
| » W: Dave LaRoche (4-9) L: Roger Erickson (0-7) S: Mark Clear (11) | Third | 4 out |
| » Defeated Angels (63-49), 7-1 | Metropolitan Stadium (28-27) | 57-51 | |
| » W: Pete Redfern (6-1) L: Steve Eddy (1-1) S: Mike Marshall (22) | Third | 4 out |
| Monday, August 6 |
| » Lost to Mariners (48-65), 7-4 | Kingdome (3-1) | 57-52 | |
| » W: Rick Honeycutt (8-7) L: Darrell Jackson (2-3) S: Byron McLaughlin (10) | Third | 5 out |
| Tuesday, August 7 |
| » Defeated Mariners (48-66), 5-2 | Kingdome (4-1) | 58-52 | |
| » W: Jerry Koosman (13-10) L: Rich Hinton (1-3) S: Mike Marshall (23) | Second | 4 out |
| Wednesday, August 8 |
| » Defeated Mariners (48-67), 3-1 | Kingdome (5-1) | 59-52 | Won 2 |
| » W: Dave Goltz (11-8) L: Floyd Bannister (6-11) S: Mike Marshall (24) | Second | 4 out |
| Friday, August 10 |
| » Lost to Athletics (35-80), 6-5 | Metropolitan Stadium (28-28) | 59-53 | |
| » W: Dave Heaverlo (4-9) L: Mike Marshall (10-10) | Second | 3½ out |
| » Defeated Athletics (35-81), 3-2 | Metropolitan Stadium (29-28) | 60-53 | |
| » W: Darrell Jackson (3-3) L: Dave Heaverlo (4-10) | Second | 3½ out |
| Saturday, August 11 |
| » Defeated Athletics (35-82), 9-7 | Metropolitan Stadium (30-28) | 61-53 | Won 2 |
| » W: Mike Bacsik (3-1) L: Steve McCatty (7-7) S: Mike Marshall (25) | Second | 3½ out |
| Sunday, August 12 |
| » Defeated Athletics (35-83), 1-0 | Metropolitan Stadium (31-28) | 62-53 | Won 3 |
| » W: Jerry Koosman (14-10) L: Rick Langford (7-13) | Second | 3½ out |
| Monday, August 13 |
| » Lost to Red Sox (71-44), 6-5 | Fenway Park (0-4) | 62-54 | |
| » W: Tom Burgmeier (3-1) L: Mike Marshall (10-11) S: Dick Drago (8) | Second | 3½ out |
| Tuesday, August 14 |
| » Lost to Red Sox (72-44), 12-1 | Fenway Park (0-5) | 62-55 | Lost 2 |
| » W: Dennis Eckersley (16-5) L: Pete Redfern (6-2) | Second | 3½ out |
| Wednesday, August 15 |
| » Lost to Red Sox (73-44), 9-5 | Fenway Park (0-6) | 62-56 | Lost 3 |
| » W: Dick Drago (9-3) L: Mike Bacsik (3-2) | Second | 3½ out |
| Thursday, August 16 |
| » Defeated Yankees (64-54), 5-1 | Yankee Stadium (2-1) | 63-56 | |
| » W: Geoff Zahn (10-3) L: Catfish Hunter (2-8) | Second | 3 out |
| Friday, August 17 |
| » Defeated Yankees (64-55), 5-2 | Yankee Stadium (3-1) | 64-56 | Won 2 |
| » W: Jerry Koosman (15-10) L: Jim Beattie (3-4) | Second | 2 out |
| Saturday, August 18 |
| » Lost to Yankees (65-55), 5-3 | Yankee Stadium (3-2) | 64-57 | |
| » W: Ron Davis (10-2) L: Mike Marshall (10-12) S: Rich Gossage (9) | Second | 3 out |
| Sunday, August 19 |
| » Lost to Yankees (66-55), 4-3 | Yankee Stadium (3-3) | 64-58 | Lost 2 |
| » W: Ron Guidry (12-7) L: Darrell Jackson (3-4) S: Rich Gossage (10) | Second | 4 out |
| Monday, August 20 |
| » Defeated Red Sox (75-47), 10-5 | Metropolitan Stadium (32-28) | 65-58 | |
| » W: Roger Erickson (1-7) L: Mike Torrez (13-8) | Second | 4 out |
| Tuesday, August 21 |
| » Defeated Red Sox (75-48), 7-2 | Metropolitan Stadium (33-28) | 66-58 | Won 2 |
| » W: Jerry Koosman (16-10) L: John Tudor (0-1) | Second | 3 out |
| Wednesday, August 22 |
| » Lost to Red Sox (76-48), 9-4 | Metropolitan Stadium (33-29) | 66-59 | |
| » W: Bob Stanley (12-9) L: Dave Goltz (11-9) | Second | 3 out |
| Friday, August 24 |
| » Lost to Yankees (69-56), 7-5 | Metropolitan Stadium (33-30) | 66-60 | Lost 2 |
| » W: Ron Guidry (13-7) L: Geoff Zahn (10-4) S: Rich Gossage (11) | Second | 3 out |
| Saturday, August 25 |
| » Defeated Yankees (69-57), 4-1 | Metropolitan Stadium (34-30) | 67-60 | |
| » W: Jerry Koosman (17-10) L: Luis Tiant (10-7) S: Mike Marshall (26) | Second | 3 out |
| Monday, August 27 |
| » Defeated Orioles (83-44), 4-3 | Metropolitan Stadium (35-30) | 68-60 | Won 2 |
| » W: Pete Redfern (7-2) L: Dennis Martinez (14-11) S: Mike Marshall (27) | Third | 2 out |
| » Lost to Orioles (84-44), 5-1 | Metropolitan Stadium (35-31) | 68-61 | |
| » W: Jim Palmer (8-4) L: Dave Goltz (11-10) | Third | 2 out |
| Wednesday, August 29 |
| » Lost to Orioles (85-44), 4-0 | Metropolitan Stadium (35-32) | 68-62 | Lost 2 |
| » W: Scott McGregor (10-4) L: Roger Erickson (1-8) | Third | 2 out |
| » Lost to Orioles (86-44), 7-4 | Metropolitan Stadium (35-33) | 68-63 | Lost 3 |
| » W: Dave Ford (2-0) L: Geoff Zahn (10-5) S: Don Stanhouse (15) | Third | 2 out |
| Thursday, August 30 |
| » Lost to Orioles (87-44), 5-4 | Memorial Stadium (1-2) | 68-64 | Lost 4 |
| » W: Mike Flanagan (19-7) L: Jerry Koosman (17-11) S: Don Stanhouse (16) | Third | 2½ out |
| Future Twin Luis Rivas is born in LaGuaira, Venezuela. |
| Friday, August 31 |
| » Defeated Orioles (87-45), 3-1 | Memorial Stadium (2-2) | 69-64 | |
| » W: Dave Goltz (12-10) L: Dennis Martinez (14-12) S: Mike Marshall (28) | Third | 2 out |
| Saturday, September 1 |
| » Defeated Orioles (87-46), 3-2 | Memorial Stadium (3-2) | 70-64 | Won 2 |
| » W: Paul Hartzell (6-7) L: Jim Palmer (8-5) S: Mike Marshall (29) | Third | 2 out |
| » Major-league debuts: Mark Corey (Orioles) |
| Sunday, September 2 |
| » Lost to Orioles (88-46), 3-1 | Memorial Stadium (3-3) | 70-65 | |
| » W: Scott McGregor (11-4) L: Roger Erickson (1-9) | Third | 3 out |
| Monday, September 3 |
| » Lost to Royals (73-64), 1-0 | Metropolitan Stadium (35-34) | 70-66 | Lost 2 |
| » W: Dennis Leonard (11-9) L: Geoff Zahn (10-6) | Third | 4 out |
| » Major-league debuts: Gary Ward (Twins) |
| Tuesday, September 4 |
| » Defeated Royals (73-65), 5-1 | Metropolitan Stadium (36-34) | 71-66 | |
| » W: Jerry Koosman (18-11) L: Larry Gura (10-10) | Third | 3 out |
| Wednesday, September 5 |
| » Defeated Royals (73-66), 8-3 | Metropolitan Stadium (37-34) | 72-66 | Won 2 |
| » W: Dave Goltz (13-10) L: Paul Splittorff (13-15) | Third | 3 out |
| » Major-league debuts: Craig Eaton (Royals) |
| Friday, September 7 |
| » Lost to Rangers (69-72), 5-4 | Metropolitan Stadium (37-35) | 72-67 | |
| » W: Sparky Lyle (5-8) L: Mike Marshall (10-13) S: Jim Kern (24) | Third | 4½ out |
| Saturday, September 8 |
| » Lost to Rangers (70-72), 6-2 | Metropolitan Stadium (37-36) | 72-68 | Lost 2 |
| » W: Doc Medich (8-6) L: Jerry Koosman (18-12) S: Jim Kern (25) | Third | 5½ out |
| Sunday, September 9 |
| » Lost to Rangers (71-72), 6-5 | Metropolitan Stadium (37-37) | 72-69 | Lost 3 |
| » W: Steve Comer (15-10) L: Paul Hartzell (6-8) S: Jim Kern (26) | Third | 6½ out |
| Monday, September 10 |
| » Lost to Royals (76-67), 6-5 | Royals Stadium (2-2) | 72-70 | Lost 4 |
| » W: Dan Quisenberry (3-2) L: Mike Marshall (10-14) | Third | 6½ out |
| » Defeated Royals (76-68), 5-2 | Royals Stadium (3-2) | 73-70 | |
| » W: Dave Goltz (14-10) L: Paul Splittorff (13-16) | Third | 6½ out |
| Tuesday, September 11 |
| » Defeated Royals (76-69), 3-1 | Royals Stadium (4-2) | 74-70 | Won 2 |
| » W: Geoff Zahn (11-6) L: Craig Chamberlain (4-2) S: Mike Marshall (30) | Third | 5½ out |
| Wednesday, September 12 |
| » Lost to Royals (77-69), 4-0 | Royals Stadium (4-3) | 74-71 | |
| » W: Dennis Leonard (12-10) L: Jerry Koosman (18-13) | Third | 5½ out |
| Thursday, September 13 |
| » Defeated Rangers (73-74), 7-4 | Arlington Stadium (2-2) | 75-71 | |
| » W: Darrell Jackson (4-4) L: Jim Kern (12-5) | Third | 5 out |
| Friday, September 14 |
| » Lost to Rangers (74-74), 5-3 | Arlington Stadium (2-3) | 75-72 | |
| » W: Fergie Jenkins (14-13) L: Dave Goltz (14-11) S: Sparky Lyle (12) | Third | 6 out |
| Saturday, September 15 |
| » Defeated Rangers (74-75), 11-4 | Arlington Stadium (3-3) | 76-72 | |
| » W: Geoff Zahn (12-6) L: Doyle Alexander (4-7) | Third | 5 out |
| Sunday, September 16 |
| » Defeated Rangers (74-76), 6-2 | Arlington Stadium (4-3) | 77-72 | Won 2 |
| » W: Roger Erickson (2-9) L: Doc Medich (9-7) | Third | 4 out |
| Monday, September 17 |
| » Defeated White Sox (65-83), 10-3 | Comiskey Park I (5-0) | 78-72 | Won 3 |
| » W: Mike Bacsik (4-2) L: Rich Wortham (14-12) | Third | 3 out |
| Tuesday, September 18 |
| » Lost to White Sox (66-83), 1-0 | Comiskey Park I (5-1) | 78-73 | |
| » W: Ken Kravec (13-13) L: Dave Goltz (14-12) | Third | 4 out |
| Wednesday, September 19 |
| » Lost to White Sox (67-83), 6-0 | Comiskey Park I (5-2) | 78-74 | Lost 2 |
| » W: Ross Baumgarten (13-8) L: Paul Hartzell (6-9) | Third | 4 out |
| Thursday, September 20 |
| » Defeated Yankees (81-70), 3-1 | Metropolitan Stadium (38-37) | < |
