| Monday, January 15 |
| Future Padre Ben Howard is born in Danville, IL. |
| Sunday, February 11 |
| Future Padre Eric Cyr is born in Montreal, PQ. |
| Saturday, February 24 |
| Future Padre Dennis Tankersley is born in Troy, MO. |
| Wednesday, March 14 |
| Future Padre Jose Nunez is born in Monte Cristi, D.R. |
| Wednesday, April 4 |
| » Major-league debuts: Mark Clear (Angels) |
| Thursday, April 5 |
| » Defeated Dodgers (0-1), 4-3 | Dodger Stadium (1-0) | 1-0 | |
| » W: Gaylord Perry (1-0) L: Lance Rautzhan (0-1) S: Rollie Fingers (1) | First | -- |
| Friday, April 6 |
| » Lost to Dodgers (1-1), 10-1 | Dodger Stadium (1-1) | 1-1 | |
| » W: Don Sutton (1-0) L: Randy Jones (0-1) | Third | 1 out |
| Saturday, April 7 |
| » Lost to Dodgers (2-1), 5-2 | Dodger Stadium (1-2) | 1-2 | Lost 2 |
| » W: Andy Messersmith (1-0) L: Eric Rasmussen (0-1) S: Lance Rautzhan (1) | Fourth | 2 out |
| Sunday, April 8 |
| » Lost to Dodgers (3-1), 6-5 | Dodger Stadium (1-3) | 1-3 | Lost 3 |
| » W: Rick Sutcliffe (1-0) L: Bob Shirley (0-1) | Third | 2½ out |
| Tuesday, April 10 |
| » Lost to Giants (4-1), 4-2 | Candlestick Park (0-1) | 1-4 | Lost 4 |
| » W: Vida Blue (2-0) L: John D'Acquisto (0-1) | Fourth | 3 out |
| Wednesday, April 11 |
| » Defeated Giants (4-2), 4-1 | Candlestick Park (1-1) | 2-4 | |
| » W: Randy Jones (1-1) L: John Montefusco (1-1) S: Rollie Fingers (2) | Fifth | 3 out |
| Thursday, April 12 |
| » Lost to Giants (5-2), 4-3 | Candlestick Park (1-2) | 2-5 | |
| » W: Bob Knepper (1-0) L: Eric Rasmussen (0-2) S: Dave Roberts (2) | Fifth | 3½ out |
| Friday, April 13 |
| » Lost to Reds (4-4), 4-2 | San Diego/Jack Murphy Stadium (0-1) | 2-6 | Lost 2 |
| » W: Bill Bonham (1-0) L: Bob Shirley (0-2) S: Frank Pastore (2) | Sixth | 4 out |
| Saturday, April 14 |
| » Defeated Reds (4-5), 3-2 | San Diego/Jack Murphy Stadium (1-1) | 3-6 | |
| » W: Gaylord Perry (2-0) L: Tom Seaver (1-2) | Fifth | 4 out |
| Sunday, April 15 |
| » Defeated Reds (4-6), 6-3 | San Diego/Jack Murphy Stadium (2-1) | 4-6 | Won 2 |
| » W: Randy Jones (2-1) L: Fred Norman (0-2) S: John D'Acquisto (1) | Fifth | 3½ out |
| » Lost to Reds (5-6), 7-5 | San Diego/Jack Murphy Stadium (2-2) | 4-7 | |
| » W: Doug Capilla (1-0) L: Mark Lee (0-1) S: Doug Bair (1) | Fifth | 3½ out |
| Tuesday, April 17 |
| » Defeated Giants (7-5), 4-3 | San Diego/Jack Murphy Stadium (3-2) | 5-7 | |
| » W: Rollie Fingers (1-0) L: Bob Knepper (1-1) | Fifth | 3 out |
| Wednesday, April 18 |
| » Defeated Giants (7-6), 7-6 | San Diego/Jack Murphy Stadium (4-2) | 6-7 | Won 2 |
| » W: Steve Mura (1-0) L: Tom Griffin (1-2) | Fourth | 3 out |
| Thursday, April 19 |
| » Lost to Giants (8-6), 14-10 | San Diego/Jack Murphy Stadium (4-3) | 6-8 | |
| » W: Vida Blue (4-0) L: Mickey Lolich (0-1) | Fourth | 3½ out |
| Friday, April 20 |
| » Defeated Braves (4-9), 7-4 | Atlanta-Fulton County Stadium (1-0) | 7-8 | |
| » W: Randy Jones (3-1) L: Rick Matula (1-2) | Fourth | 3½ out |
| » Major-league debuts: Mike Macha and Rick Mahler (Braves) |
| Saturday, April 21 |
| » Defeated Braves (4-10), 9-5 | Atlanta-Fulton County Stadium (2-0) | 8-8 | Won 2 |
| » W: John D'Acquisto (1-1) L: Gene Garber (0-1) | Fourth | 3½ out |
| Sunday, April 22 |
| » Lost to Braves (5-10), 8-7 | Atlanta-Fulton County Stadium (2-1) | 8-9 | |
| » W: Gene Garber (1-1) L: Rollie Fingers (1-1) | Fourth | 4½ out |
| Tuesday, April 24 |
| » Lost to Expos (9-5), 5-1 | Stade Olympique (0-1) | 8-10 | Lost 2 |
| » W: Ross Grimsley (2-0) L: Randy Jones (3-2) | Fourth | 5 out |
| Wednesday, April 25 |
| » Lost to Expos (10-5), 9-6 | Stade Olympique (0-2) | 8-11 | Lost 3 |
| » W: Steve Rogers (1-1) L: Bob Shirley (0-3) S: David Palmer (2) | Fourth | 5 out |
| Friday, April 27 |
| » Lost to Phillies (12-4), 2-0 | Veteran's Stadium (0-1) | 8-12 | Lost 4 |
| » W: Nino Espinosa (3-0) L: Gaylord Perry (2-1) | Fourth | 6½ out |
| Saturday, April 28 |
| » Defeated Phillies (12-5), 5-0 | Veteran's Stadium (1-1) | 9-12 | |
| » W: John D'Acquisto (2-1) L: Steve Carlton (2-3) | Third | 6 out |
| Sunday, April 29 |
| » Lost to Phillies (13-5), 4-3 | Veteran's Stadium (1-2) | 9-13 | |
| » W: Ron Reed (3-1) L: Rollie Fingers (1-2) | Fourth | 6 out |
| Monday, April 30 |
| » Lost to Mets (8-10), 4-3 | Shea Stadium (0-1) | 9-14 | Lost 2 |
| » W: Craig Swan (3-2) L: Bob Shirley (0-4) S: Skip Lockwood (4) | Fourth | 7 out |
| Tuesday, May 1 |
| » Defeated Mets (8-11), 10-5 | Shea Stadium (1-1) | 10-14 | |
| » W: Gaylord Perry (3-1) L: Dale Murray (1-3) S: Rollie Fingers (3) | Third | 6 out |
| Thursday, May 3 |
| » Defeated Expos (15-6), 10-2 | San Diego/Jack Murphy Stadium (5-3) | 11-14 | Won 2 |
| » W: Randy Jones (4-2) L: Scott Sanderson (1-2) S: Rollie Fingers (4) | Third | 5½ out |
| Friday, May 4 |
| » Lost to Expos (16-6), 12-1 | San Diego/Jack Murphy Stadium (5-4) | 11-15 | |
| » W: Ross Grimsley (3-0) L: John D'Acquisto (2-2) | Fourth | 5½ out |
| Saturday, May 5 |
| » Defeated Expos (16-7), 6-3 | San Diego/Jack Murphy Stadium (6-4) | 12-15 | |
| » W: Steve Mura (2-0) L: Woodie Fryman (1-2) S: Rollie Fingers (5) | Fourth | 4½ out |
| Sunday, May 6 |
| » Lost to Expos (17-7), 7-5 | San Diego/Jack Murphy Stadium (6-5) | 12-16 | |
| » W: Bill Lee (4-0) L: Gaylord Perry (3-2) S: Woodie Fryman (1) | Fourth | 5 out |
| Monday, May 7 |
| » Lost to Phillies (18-7), 11-6 | San Diego/Jack Murphy Stadium (6-6) | 12-17 | Lost 2 |
| » W: Steve Carlton (3-4) L: Bob Owchinko (0-1) S: Rawly Eastwick (1) | Fourth | 5½ out |
| Tuesday, May 8 |
| » Lost to Phillies (19-7), 9-8 | San Diego/Jack Murphy Stadium (6-7) | 12-18 | Lost 3 |
| » W: Jim Kaat (1-0) L: John D'Acquisto (2-3) | Fifth | 5½ out |
| Wednesday, May 9 |
| » Lost to Phillies (20-7), 2-0 | San Diego/Jack Murphy Stadium (6-8) | 12-19 | Lost 4 |
| » W: Dick Ruthven (6-0) L: Eric Rasmussen (0-3) | Fifth | 6½ out |
| Thursday, May 10 |
| » Lost to Phillies (21-7), 3-2 | San Diego/Jack Murphy Stadium (6-9) | 12-20 | Lost 5 |
| » W: Nino Espinosa (5-1) L: Gaylord Perry (3-3) S: Ron Reed (2) | Fifth | 6½ out |
| Friday, May 11 |
| » Lost to Mets (10-18), 4-0 | San Diego/Jack Murphy Stadium (6-10) | 12-21 | Lost 6 |
| » W: Kevin Kobel (1-0) L: Steve Mura (2-1) | Fifth | 7 out |
| Saturday, May 12 |
| » Defeated Mets (10-19), 2-1 | San Diego/Jack Murphy Stadium (7-10) | 13-21 | |
| » W: Bob Owchinko (1-1) L: Neil Allen (0-5) | Fifth | 6 out |
| Sunday, May 13 |
| » Defeated Mets (10-20), 5-4 | San Diego/Jack Murphy Stadium (8-10) | 14-21 | Won 2 |
| » W: Bob Shirley (1-4) L: Skip Lockwood (0-4) | Fifth | 6 out |
| Monday, May 14 |
| » Lost to Reds (20-14), 7-4 | Riverfront Stadium (0-1) | 14-22 | |
| » W: Paul Moskau (3-0) L: Eric Rasmussen (0-4) S: Dave Tomlin (1) | Fifth | 7 out |
| Tuesday, May 15 |
| » Defeated Reds (20-15), 2-1 | Riverfront Stadium (1-1) | 15-22 | |
| » W: Rollie Fingers (2-2) L: Frank Pastore (1-4) | Fifth | 6 out |
| Wednesday, May 16 |
| » Lost to Reds (21-15), 7-0 | Riverfront Stadium (1-2) | 15-23 | |
| » W: Bill Bonham (2-0) L: Steve Mura (2-2) | Fifth | 7 out |
| Friday, May 18 |
| » Lost to Astros (21-18), 3-2 | Astrodome (0-1) | 15-24 | Lost 2 |
| » W: Joe Niekro (4-2) L: Rollie Fingers (2-3) | Fifth | 8 out |
| Saturday, May 19 |
| » Defeated Astros (21-19), 4-2 | Astrodome (1-1) | 16-24 | |
| » W: Rollie Fingers (3-3) L: J.R. Richard (4-4) | Fourth | 8 out |
| Sunday, May 20 |
| » Lost to Astros (22-19), 1-0 | Astrodome (1-2) | 16-25 | |
| » W: Rick Williams (1-1) L: Gaylord Perry (3-4) | Fifth | 8½ out |
| » Lost to Astros (23-19), 6-3 | Astrodome (1-3) | 16-26 | Lost 2 |
| » W: Joaquin Andujar (4-1) L: John D'Acquisto (2-4) | Fifth | 8½ out |
| » Major-league debuts: Randy Niemann (Astros) |
| Monday, May 21 |
| » Defeated Dodgers (20-23), 3-2 | San Diego/Jack Murphy Stadium (9-10) | 17-26 | |
| » W: Eric Rasmussen (1-4) L: Andy Messersmith (2-4) | Fifth | 8 out |
| Tuesday, May 22 |
| » Defeated Dodgers (20-24), 7-6 | San Diego/Jack Murphy Stadium (10-10) | 18-26 | Won 2 |
| » W: Rollie Fingers (4-3) L: Jerry Reuss (1-4) | Fifth | 7 out |
| Wednesday, May 23 |
| » Lost to Dodgers (21-24), 4-2 | San Diego/Jack Murphy Stadium (10-11) | 18-27 | |
| » W: Burt Hooton (4-2) L: Randy Jones (4-3) | Fifth | 8 out |
| Future Padre Cesar Crespo is born in Rio Piedras, P.R. |
| Friday, May 25 |
| » Defeated Astros (24-22), 2-1 | San Diego/Jack Murphy Stadium (11-11) | 19-27 | |
| » W: Rollie Fingers (5-3) L: Joe Sambito (2-2) | Fifth | 6½ out |
| Saturday, May 26 |
| » Lost to Astros (25-22), 9-0 | San Diego/Jack Murphy Stadium (11-12) | 19-28 | |
| » W: Joe Niekro (6-2) L: Mickey Lolich (0-2) | Fifth | 7½ out |
| Sunday, May 27 |
| » Lost to Astros (26-22), 4-2 | San Diego/Jack Murphy Stadium (11-13) | 19-29 | Lost 2 |
| » W: J.R. Richard (5-4) L: Eric Rasmussen (1-5) | Fifth | 7½ out |
| Monday, May 28 |
| » Defeated Astros (26-23), 5-4 | San Diego/Jack Murphy Stadium (12-13) | 20-29 | |
| » W: Randy Jones (5-3) L: Joaquin Andujar (4-3) S: Rollie Fingers (6) | Fifth | 7½ out |
| » Major-league debuts: Bert Roberge (Astros) |
| Tuesday, May 29 |
| » Defeated Braves (18-28), 6-3 | San Diego/Jack Murphy Stadium (13-13) | 21-29 | Won 2 |
| » W: Gaylord Perry (4-4) L: Tony Brizzolara (1-1) | Fifth | 6 out |
| » Defeated Braves (18-29), 3-2 | San Diego/Jack Murphy Stadium (14-13) | 22-29 | Won 3 |
| » W: Bob Owchinko (2-1) L: Phil Niekro (5-8) S: Rollie Fingers (7) | Fifth | 6 out |
| Wednesday, May 30 |
| » Defeated Braves (18-30), 10-2 | San Diego/Jack Murphy Stadium (15-13) | 23-29 | Won 4 |
| » W: Bob Shirley (2-4) L: Bo McLaughlin (1-3) | Fifth | 5½ out |
| Thursday, May 31 |
| » Defeated Braves (18-31), 3-1 | San Diego/Jack Murphy Stadium (16-13) | 24-29 | Won 5 |
| » W: Eric Rasmussen (2-5) L: Rick Matula (2-4) S: Rollie Fingers (8) | Fifth | 5½ out |
| Friday, June 1 |
| » Lost to Pirates (24-21), 9-8 | Three Rivers Stadium (0-1) | 24-30 | |
| » W: Kent Tekulve (3-5) L: Bob Shirley (2-5) | Fifth | 6½ out |
| Saturday, June 2 |
| » Defeated Pirates (24-22), 3-1 | Three Rivers Stadium (1-1) | 25-30 | |
| » W: Gaylord Perry (5-4) L: John Candelaria (4-4) | Fifth | 6½ out |
| Sunday, June 3 |
| » Lost to Pirates (25-22), 7-0 | Three Rivers Stadium (1-2) | 25-31 | |
| » W: Bruce Kison (3-1) L: Bob Owchinko (2-2) | Fifth | 7½ out |
| Tuesday, June 5 |
| » Defeated Cubs (22-27), 11-3 | Wrigley Field (1-0) | 26-31 | |
| » W: Eric Rasmussen (3-5) L: Dennis Lamp (4-2) | Fifth | 7 out |
| Wednesday, June 6 |
| » Lost to Cubs (23-27), 3-0 | Wrigley Field (1-1) | 26-32 | |
| » W: Rick Reuschel (4-5) L: Randy Jones (5-4) S: Bruce Sutter (11) | Fifth | 8 out |
| Thursday, June 7 |
| » Lost to Cubs (24-27), 4-3 | Wrigley Field (1-2) | 26-33 | Lost 2 |
| » W: Lynn McGlothen (7-6) L: Bob Shirley (2-6) S: Bruce Sutter (12) | Fifth | 8½ out |
| Friday, June 8 |
| » Defeated Cardinals (29-22), 8-7 | Busch Stadium II (1-0) | 27-33 | |
| » W: Rollie Fingers (6-3) L: Darold Knowles (2-2) S: John D'Acquisto (2) | Fifth | 8½ out |
| Saturday, June 9 |
| » Lost to Cardinals (30-22), 7-4 | Busch Stadium II (1-1) | 27-34 | |
| » W: Pete Vuckovich (6-3) L: Eric Rasmussen (3-6) | Fifth | 8½ out |
| » Major-league debuts: Tom Tellmann (Padres) |
| Sunday, June 10 |
| » Lost to Cardinals (31-22), 3-2 | Busch Stadium II (1-2) | 27-35 | Lost 2 |
| » W: Silvio Martinez (4-1) L: Randy Jones (5-5) S: Buddy Schultz (3) | Fifth | 9½ out |
| Tuesday, June 12 |
| » Defeated Pirates (28-26), 6-3 | San Diego/Jack Murphy Stadium (17-13) | 28-35 | |
| » W: Gaylord Perry (6-4) L: John Candelaria (4-5) | Fifth | 8 out |
| Wednesday, June 13 |
| » Defeated Pirates (28-27), 3-2 | San Diego/Jack Murphy Stadium (18-13) | 29-35 | Won 2 |
| » W: Bob Owchinko (3-2) L: Bruce Kison (3-3) S: Rollie Fingers (9) | Fifth | 8 out |
| Thursday, June 14 |
| » Defeated Pirates (28-28), 2-1 | San Diego/Jack Murphy Stadium (19-13) | 30-35 | Won 3 |
| » W: John D'Acquisto (3-4) L: John Candelaria (4-6) | Fifth | 7½ out |
| Friday, June 15 |
| » Lost to Cubs (29-29), 3-2 | San Diego/Jack Murphy Stadium (19-14) | 30-36 | |
| » W: Willie Hernandez (1-0) L: John D'Acquisto (3-5) S: Dick Tidrow (5) | Fifth | 8½ out |
| Saturday, June 16 |
| » Lost to Cubs (30-29), 5-2 | San Diego/Jack Murphy Stadium (19-15) | 30-37 | Lost 2 |
| » W: Ken Holtzman (5-5) L: Gaylord Perry (6-5) S: Bruce Sutter (14) | Fifth | 8½ out |
| Sunday, June 17 |
| » Lost to Cubs (31-29), 8-5 | San Diego/Jack Murphy Stadium (19-16) | 30-38 | Lost 3 |
| » W: Mike Krukow (3-5) L: Bob Owchinko (3-3) S: Bruce Sutter (15) | Fifth | 8½ out |
| Monday, June 18 |
| » Defeated Cardinals (32-28), 3-2 | San Diego/Jack Murphy Stadium (20-16) | 31-38 | |
| » W: Randy Jones (6-5) L: Bob Forsch (3-6) S: Rollie Fingers (10) | Fifth | 8½ out |
| Tuesday, June 19 |
| » Lost to Cardinals (33-28), 7-2 | San Diego/Jack Murphy Stadium (20-17) | 31-39 | |
| » W: John Fulgham (1-0) L: Eric Rasmussen (3-7) | Fifth | 9½ out |
| » Major-league debuts: John Fulgham (Cardinals) |
| Wednesday, June 20 |
| » Defeated Cardinals (33-29), 3-1 | San Diego/Jack Murphy Stadium (21-17) | 32-39 | |
| » W: Gaylord Perry (7-5) L: Pete Vuckovich (6-4) | Fourth | 9½ out |
| Friday, June 22 |
| » Lost to Astros (42-29), 2-1 | Astrodome (1-4) | 32-40 | |
| » W: Joe Niekro (11-3) L: Bob Shirley (2-7) S: Joe Sambito (6) | Fifth | 10½ out |
| Saturday, June 23 |
| » Lost to Astros (43-29), 3-2 | Astrodome (1-5) | 32-41 | Lost 2 |
| » W: Tom Dixon (1-1) L: Rollie Fingers (6-4) | Fifth | 11½ out |
| Sunday, June 24 |
| » Lost to Astros (44-29), 4-1 | Astrodome (1-6) | 32-42 | Lost 3 |
| » W: Joaquin Andujar (8-4) L: Eric Rasmussen (3-8) | Fifth | 12½ out |
| Monday, June 25 |
| » Lost to Dodgers (33-41), 4-3 | Dodger Stadium (1-4) | 32-43 | Lost 4 |
| » W: Ken Brett (1-0) L: Rollie Fingers (6-5) | Fifth | 13 out |
| Tuesday, June 26 |
| » Defeated Dodgers (33-42), 5-1 | Dodger Stadium (2-4) | 33-43 | |
| » W: Bob Shirley (3-7) L: Don Sutton (7-8) | Fifth | 13 out |
| Wednesday, June 27 |
| » Defeated Braves (28-46), 2-1 | San Diego/Jack Murphy Stadium (22-17) | 34-43 | Won 2 |
| » W: Rollie Fingers (7-5) L: Phil Niekro (9-10) | Fourth | 12½ out |
| » Lost to Braves (29-46), 5-2 | San Diego/Jack Murphy Stadium (22-18) | 34-44 | |
| » W: Joey McLaughlin (1-1) L: Bob Owchinko (3-4) S: Gene Garber (14) | Fourth | 12½ out |
| Thursday, June 28 |
| » Defeated Braves (29-47), 6-5 | San Diego/Jack Murphy Stadium (23-18) | 35-44 | |
| » W: John D'Acquisto (4-5) L: Tony Brizzolara (2-3) S: Rollie Fingers (11) | Fourth | 12½ out |
| Friday, June 29 |
| » Lost to Astros (48-31), 4-1 | San Diego/Jack Murphy Stadium (23-19) | 35-45 | |
| » W: Joaquin Andujar (9-4) L: Gaylord Perry (7-6) | Fourth | 13½ out |
| Saturday, June 30 |
| » Lost to Astros (49-31), 3-0 | San Diego/Jack Murphy Stadium (23-20) | 35-46 | Lost 2 |
| » W: J.R. Richard (7-7) L: Bob Shirley (3-8) | Fourth | 14½ out |
| Sunday, July 1 |
| » Lost to Astros (50-31), 4-1 | San Diego/Jack Murphy Stadium (23-21) | 35-47 | Lost 3 |
| » W: Joe Niekro (12-3) L: Randy Jones (6-6) S: Joe Sambito (8) | Fourth | 15½ out |
| Monday, July 2 |
| » Lost to Dodgers (34-47), 6-3 | San Diego/Jack Murphy Stadium (23-22) | 35-48 | Lost 4 |
| » W: Ken Brett (2-1) L: Bob Owchinko (3-5) | Fourth | 16 out |
| Tuesday, July 3 |
| » Defeated Dodgers (34-48), 3-2 | San Diego/Jack Murphy Stadium (24-22) | 36-48 | |
| » W: Gaylord Perry (8-6) L: Rick Sutcliffe (7-7) | Fourth | 16 out |
| Wednesday, July 4 |
| » Defeated Dodgers (34-49), 6-0 | San Diego/Jack Murphy Stadium (25-22) | 37-48 | Won 2 |
| » W: Bob Shirley (4-8) L: Don Sutton (7-9) | Fourth | 16 out |
| Thursday, July 5 |
| » Major-league debuts: Dickie Noles (Phillies) |
| Friday, July 6 |
| » Defeated Mets (32-45), 6-5 | Shea Stadium (2-1) | 38-48 | Won 3 |
| » W: Mark Lee (1-1) L: Tom Hausman (0-4) | Fourth | 15½ out |
| Saturday, July 7 |
| » Defeated Mets (32-46), 11-3 | Shea Stadium (3-1) | 39-48 | Won 4 |
| » W: John D'Acquisto (5-5) L: Dock Ellis (1-7) S: Eric Rasmussen (1) | Fourth | 14 out |
| Sunday, July 8 |
| » Defeated Mets (32-47), 5-3 | Shea Stadium (4-1) | 40-48 | Won 5 |
| » W: Gaylord Perry (9-6) L: Kevin Kobel (3-4) | Fourth | 13½ out |
| » Lost to Mets (33-47), 4-1 | Shea Stadium (4-2) | 40-49 | |
| » W: Andy Hassler (3-4) L: Bob Shirley (4-9) S: Tom Hausman (1) | Fourth | 13½ out |
| Tuesday, July 10 |
| » Lost to Phillies (46-40), 6-5 | Veteran's Stadium (1-3) | 40-50 | Lost 2 |
| » W: Doug Bird (1-0) L: Rollie Fingers (7-6) | Fourth | 13½ out |
| Wednesday, July 11 |
| » Defeated Phillies (46-41), 7-3 | Veteran's Stadium (2-3) | 41-50 | |
| » W: John D'Acquisto (6-5) L: Randy Lerch (4-8) | Fourth | 12½ out |
| Thursday, July 12 |
| » Lost to Phillies (47-41), 4-3 | Veteran's Stadium (2-4) | 41-51 | |
| » W: Steve Carlton (11-8) L: Rollie Fingers (7-7) S: Tug McGraw (10) | Fourth | 12½ out |
| Friday, July 13 |
| » Defeated Expos (48-34), 7-5 | Stade Olympique (1-2) | 42-51 | |
| » W: Bob Owchinko (4-5) L: Elias Sosa (5-5) S: Rollie Fingers (12) | Fourth | 12 out |
| » Lost to Expos (49-34), 10-7 | Stade Olympique (1-3) | 42-52 | |
| » W: Rudy May (3-0) L: Bob Owchinko (4-6) S: Woodie Fryman (6) | Fourth | 12 out |
| » Major-league debuts: Tony Bernazard (Expos) |
| Saturday, July 14 |
| » Defeated Expos (49-35), 5-1 | Stade Olympique (2-3) | 43-52 | |
| » W: Randy Jones (7-6) L: Bill Lee (9-6) | Fourth | 12 out |
| Sunday, July 15 |
| » Lost to Expos (50-35), 4-0 | Stade Olympique (2-4) | 43-53 | |
| » W: Scott Sanderson (6-5) L: John D'Acquisto (6-6) S: Elias Sosa (10) | Fourth | 12 out |
| Thursday, July 19 |
| » Defeated Mets (38-50), 3-1 | San Diego/Jack Murphy Stadium (26-22) | 44-53 | |
| » W: Randy Jones (8-6) L: Kevin Kobel (4-5) | Fourth | 10½ out |
| Friday, July 20 |
| » Defeated Mets (38-51), 2-1 | San Diego/Jack Murphy Stadium (27-22) | 45-53 | Won 2 |
| » W: Gaylord Perry (10-6) L: Craig Swan (8-9) | Fourth | 9½ out |
| Saturday, July 21 |
| » Lost to Mets (39-51), 2-1 | San Diego/Jack Murphy Stadium (27-23) | 45-54 | |
| » W: Neil Allen (4-5) L: Bob Shirley (4-10) S: Andy Hassler (1) | Fourth | 9½ out |
| Sunday, July 22 |
| » Lost to Phillies (52-43), 5-2 | San Diego/Jack Murphy Stadium (27-24) | 45-55 | Lost 2 |
| » W: Nino Espinosa (10-7) L: John D'Acquisto (6-7) S: Tug McGraw (13) | Fourth | 10½ out |
| Monday, July 23 |
| » Defeated Phillies (52-44), 6-5 | San Diego/Jack Murphy Stadium (28-24) | 46-55 | |
| » W: Rollie Fingers (8-7) L: Ron Reed (6-5) | Fourth | 10½ out |
| Tuesday, July 24 |
| » Defeated Expos (53-39), 4-3 | San Diego/Jack Murphy Stadium (29-24) | 47-55 | Won 2 |
| » W: Steve Mura (3-2) L: David Palmer (2-2) | Fourth | 10½ out |
| Wednesday, July 25 |
| » Lost to Expos (54-39), 6-5 | San Diego/Jack Murphy Stadium (29-25) | 47-56 | |
| » W: Rudy May (5-0) L: Bob Owchinko (4-7) S: Elias Sosa (11) | Fourth | 11½ out |
| Thursday, July 26 |
| » Lost to Giants (49-53), 6-2 | San Diego/Jack Murphy Stadium (29-26) | 47-57 | Lost 2 |
| » W: Ed Whitson (4-5) L: John D'Acquisto (6-8) S: Gary Lavelle (12) | Fourth | 11½ out |
| Friday, July 27 |
| » Lost to Giants (50-53), 4-3 | San Diego/Jack Murphy Stadium (29-27) | 47-58 | Lost 3 |
| » W: Pedro Borbon (5-3) L: Mark Lee (1-2) | Fourth | 11½ out |
| Saturday, July 28 |
| » Defeated Giants (50-54), 4-3 | San Diego/Jack Murphy Stadium (30-27) | 48-58 | |
| » W: Rollie Fingers (9-7) L: Pedro Borbon (5-4) | Fourth | 11½ out |
| Sunday, July 29 |
| » Lost to Giants (51-54), 4-2 | San Diego/Jack Murphy Stadium (30-28) | 48-59 | |
| » W: John Montefusco (3-4) L: Bob Shirley (4-11) S: Gary Lavelle (13) | Fourth | 12½ out |
| Tuesday, July 31 |
| » Defeated Braves (43-64), 10-3 | Atlanta-Fulton County Stadium (3-1) | 49-59 | |
| » W: John D'Acquisto (7-8) L: Phil Niekro (14-13) S: Mark Lee (1) | Fourth | 12 out |
| Wednesday, August 1 |
| » Lost to Braves (44-64), 5-4 | Atlanta-Fulton County Stadium (3-2) | 49-60 | |
| » W: Joey McLaughlin (4-1) L: Rollie Fingers (9-8) S: Gene Garber (19) | Fourth | 13 out |
| Thursday, August 2 |
| » Lost to Braves (45-64), 7-2 | Atlanta-Fulton County Stadium (3-3) | 49-61 | Lost 2 |
| » W: Tony Brizzolara (6-6) L: Gaylord Perry (10-7) | Fourth | 13½ out |
| Friday, August 3 |
| » Defeated Reds (59-52), 6-4 | Riverfront Stadium (2-2) | 50-61 | |
| » W: Bob Shirley (5-11) L: Bill Bonham (5-5) S: Mark Lee (2) | Fourth | 13½ out |
| Saturday, August 4 |
| » Lost to Reds (60-52), 7-1 | Riverfront Stadium (2-3) | 50-62 | |
| » W: Fred Norman (9-8) L: John D'Acquisto (7-9) | Fourth | 15 out |
| Sunday, August 5 |
| » Lost to Reds (61-52), 9-1 | Riverfront Stadium (2-4) | 50-63 | Lost 2 |
| » W: Frank Pastore (2-5) L: Randy Jones (8-7) | Fourth | 16 out |
| Tuesday, August 7 |
| » Lost to Giants (54-59), 3-2 | Candlestick Park (1-3) | 50-64 | Lost 3 |
| » W: Vida Blue (9-9) L: Gaylord Perry (10-8) S: Gary Lavelle (14) | Fourth | 16 out |
| Wednesday, August 8 |
| » Lost to Giants (55-59), 10-7 | Candlestick Park (1-4) | 50-65 | Lost 4 |
| » W: John Curtis (7-7) L: Bob Shirley (5-12) S: Gary Lavelle (15) | Fourth | 17 out |
| Future Padre Humberto Quintero is born in Maracaibo, Venezuela. |
| Thursday, August 9 |
| » Defeated Giants (55-60), 4-0 | Candlestick Park (2-4) | 51-65 | |
| » W: John D'Acquisto (8-9) L: Greg Minton (1-2) | Fourth | 16 out |
| Friday, August 10 |
| » Defeated Reds (64-54), 3-2 | San Diego/Jack Murphy Stadium (31-28) | 52-65 | Won 2 |
| » W: Randy Jones (9-7) L: Frank Pastore (2-6) | Fourth | 16 out |
| Sunday, August 12 |
| » Lost to Reds (65-54), 9-2 | San Diego/Jack Murphy Stadium (31-29) | 52-66 | |
| » W: Tom Seaver (11-5) L: Gaylord Perry (10-9) | Fourth | 15½ out |
| » Defeated Reds (65-55), 5-4 | San Diego/Jack Murphy Stadium (32-29) | 53-66 | |
| » W: Mark Lee (2-2) L: Mike LaCoss (12-5) S: Eric Rasmussen (2) | Fourth | 15½ out |
| Monday, August 13 |
| » Major-league debuts: Tom Herr (Cardinals) |
| Tuesday, August 14 |
| » Lost to Pirates (68-49), 7-1 | Three Rivers Stadium (1-3) | 53-67 | |
| » W: John Candelaria (11-8) L: John D'Acquisto (8-10) | Fifth | 17 out |
| Wednesday, August 15 |
| » Lost to Pirates (69-49), 5-1 | Three Rivers Stadium (1-4) | 53-68 | Lost 2 |
| » W: Bert Blyleven (10-4) L: Randy Jones (9-8) | Fifth | 17 out |
| Thursday, August 16 |
| » Lost to Pirates (70-49), 5-4 | Three Rivers Stadium (1-5) | 53-69 | Lost 3 |
| » W: Bruce Kison (8-6) L: Gaylord Perry (10-10) S: Enrique Romo (4) | Fifth | 17½ out |
| Friday, August 17 |
| » Lost to Cubs (64-54), 9-6 | Wrigley Field (1-3) | 53-70 | Lost 4 |
| » W: Dick Tidrow (11-4) L: John D'Acquisto (8-11) S: Bruce Sutter (30) | Fifth | 17½ out |
| Saturday, August 18 |
| » Lost to Cubs (65-54), 3-2 | Wrigley Field (1-4) | 53-71 | Lost 5 |
| » W: Dick Tidrow (12-4) L: Rollie Fingers (9-9) | Fifth | 17½ out |
| Sunday, August 19 |
| » Lost to Cubs (66-54), 3-1 | Wrigley Field (1-5) | 53-72 | Lost 6 |
| » W: Rick Reuschel (14-7) L: Randy Jones (9-9) S: Bruce Sutter (31) | Fifth | 17½ out |
| Monday, August 20 |
| » Lost to Cardinals (64-58), 6-3 | Busch Stadium II (1-3) | 53-73 | Lost 7 |
| » W: Silvio Martinez (11-6) L: Gaylord Perry (10-11) | Fifth | 18½ out |
| Tuesday, August 21 |
| » Defeated Cardinals (64-59), 3-2 | Busch Stadium II (2-3) | 54-73 | |
| » W: Bob Shirley (6-12) L: Will McEnaney (0-2) S: Rollie Fingers (13) | Fifth | 17½ out |
| Wednesday, August 22 |
| » Lost to Cardinals (65-59), 8-5 | Busch Stadium II (2-4) | 54-74 | |
| » W: John Fulgham (6-4) L: Bob Owchinko (4-8) | Fifth | 18½ out |
| Friday, August 24 |
| » Defeated Pirates (73-53), 3-2 | San Diego/Jack Murphy Stadium (33-29) | 55-74 | |
| » W: Randy Jones (10-9) L: Enrique Romo (10-4) S: Mark Lee (3) | Fifth | 17½ out |
| Saturday, August 25 |
| » Lost to Pirates (74-53), 4-3 | San Diego/Jack Murphy Stadium (33-30) | 55-75 | |
| » W: Dave Roberts (2-3) L: John D'Acquisto (8-12) | Fifth | 18½ out |
| Sunday, August 26 |
| » Lost to Pirates (75-53), 9-2 | San Diego/Jack Murphy Stadium (33-31) | 55-76 | Lost 2 |
| » W: Bruce Kison (9-7) L: Bob Shirley (6-13) | Fifth | 19½ out |
| Monday, August 27 |
| » Defeated Cubs (69-58), 5-4 | San Diego/Jack Murphy Stadium (34-31) | 56-76 | |
| » W: John D'Acquisto (9-12) L: Willie Hernandez (4-3) | Fifth | 19½ out |
| Tuesday, August 28 |
| » Lost to Cubs (70-58), 3-1 | San Diego/Jack Murphy Stadium (34-32) | 56-77 | |
| » W: Rick Reuschel (16-7) L: Randy Jones (10-10) S: Bruce Sutter (34) | Fifth | 20 out |
| Wednesday, August 29 |
| » Defeated Cubs (70-59), 3-1 | San Diego/Jack Murphy Stadium (35-32) | 57-77 | |
| » W: Gaylord Perry (11-11) L: Lynn McGlothen (11-10) | Fifth | 20 out |
| Friday, August 31 |
| » Lost to Cardinals (70-61), 8-7 | San Diego/Jack Murphy Stadium (35-33) | 57-78 | |
| » W: Dan O'Brien (1-0) L: Bob Owchinko (4-9) | Fifth | 20 out |
| Saturday, September 1 |
| » Lost to Cardinals (71-61), 5-3 | San Diego/Jack Murphy Stadium (35-34) | 57-79 | Lost 2 |
| » W: Silvio Martinez (12-7) L: Randy Jones (10-11) | Fifth | 20½ out |
| Sunday, September 2 |
| » Lost to Cardinals (72-61), 2-1 | San Diego/Jack Murphy Stadium (35-35) | 57-80 | Lost 3 |
| » W: Bob Forsch (8-10) L: Mark Lee (2-3) | Fifth | 20½ out |
| Monday, September 3 |
| » Defeated Giants (60-78), 3-0 | San Diego/Jack Murphy Stadium (36-35) | 58-80 | |
| » W: Gaylord Perry (12-11) L: Ed Whitson (6-9) S: Eric Rasmussen (3) | Fifth | 20 out |
| » Major-league debuts: Tim Flannery (Padres) |
| Tuesday, September 4 |
| » Lost to Giants (61-78), 3-1 | San Diego/Jack Murphy Stadium (36-36) | 58-81 | |
| » W: John Curtis (10-9) L: Bob Shirley (6-14) S: Gary Lavelle (16) | Fifth | 20½ out |
| Wednesday, September 5 |
| » Lost to Astros (79-60), 4-3 | Astrodome (1-7) | 58-82 | Lost 2 |
| » W: Joe Sambito (7-4) L: John D'Acquisto (9-13) | Fifth | 21½ out |
| Thursday, September 6 |
| » Lost to Astros (80-60), 2-0 | Astrodome (1-8) | 58-83 | Lost 3 |
| » W: J.R. Richard (16-12) L: Bob Owchinko (4-10) | Fifth | 22½ out |
| Friday, September 7 |
| » Defeated Braves (55-85), 8-0 | Atlanta-Fulton County Stadium (4-3) | 59-83 | |
| » W: Eric Rasmussen (4-8) L: Eddie Solomon (6-11) | Fifth | 21½ out |
| Saturday, September 8 |
| » Defeated Braves (55-86), 9-2 | Atlanta-Fulton County Stadium (5-3) | 60-83 | Won 2 |
| » W: Bob Shirley (7-14) L: Rick Matula (7-9) | Fifth | 21 out |
| Sunday, September 9 |
| » Defeated Braves (55-87), 4-1 | Atlanta-Fulton County Stadium (6-3) | 61-83 | Won 3 |
| » W: Randy Jones (11-11) L: Phil Niekro (17-19) S: Steve Mura (1) | Fifth | 20½ out |
| Tuesday, September 11 |
| » Defeated Dodgers (68-76), 3-1 | Dodger Stadium (3-4) | 62-83 | Won 4 |
| » W: Bob Owchinko (5-10) L: Don Sutton (12-14) S: Steve Mura (2) | Fifth | 20 out |
| Wednesday, September 12 |
| » Lost to Dodgers (69-76), 5-2 | Dodger Stadium (3-5) | 62-84 | |
| » W: Charlie Hough (5-5) L: Eric Rasmussen (4-9) S: Bobby Castillo (6) | Fifth | 21 out |
| Thursday, September 13 |
| » Lost to Dodgers (70-76), 8-6 | Dodger Stadium (3-6) | 62-85 | Lost 2 |
| » W: Jerry Reuss (6-13) L: Bob Shirley (7-15) S: Ken Brett (2) | Fifth | 21½ out |
| Friday, September 14 |
| » Lost to Braves (58-88), 10-7 | San Diego/Jack Murphy Stadium (36-37) | 62-86 | Lost 3 |
| » W: Mickey Mahler (4-11) L: Mark Lee (2-4) S: Gene Garber (23) | Fifth | 21½ out |
| Saturday, September 15 |
| » Lost to Braves (59-88), 6-1 | San Diego/Jack Murphy Stadium (36-38) | 62-87 | Lost 4 |
| » W: Rick Matula (8-9) L: Juan Eichelberger (0-1) S: Larry Bradford (2) | Fifth | 22½ out |
| Monday, September 17 |
| » Lost to Astros (83-66), 1-0 | San Diego/Jack Murphy Stadium (36-39) | 62-88 | Lost 5 |
| » W: Joe Niekro (19-10) L: Bob Owchinko (5-11) | Fifth | 23 out |
| Tuesday, September 18 |
| » Defeated Astros (83-67), 4-0 | San Diego/Jack Murphy Stadium (37-39) | 63-88 | |
| » W: Eric Rasmussen (5-9) L: Rick Williams (4-6) | Fifth | 22 out |
| Wednesday, September 19 |
| » Lost to Reds (86-66), 3-2 | San Diego/Jack Murphy Stadium (37-40) | 63-89 | |
| » W: Bill Bonham (9-6) L: Bob Shirley (7-16) S: Tom Hume (16) | Fifth | 23 out |
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