| Thursday, February 15 |
| Future Mariner Luis Ugueto is born in Caracas, Venezuela. |
| Wednesday, April 4 |
| » Defeated Angels (0-1), 5-4 | Kingdome (1-0) | 1-0 | |
| » W: John Montague (1-0) L: Frank Tanana (0-1) | First | -- |
| » Major-league debuts: Mark Clear (Angels) |
| Friday, April 6 |
| » Defeated Angels (0-2), 14-6 | Kingdome (2-0) | 2-0 | Won 2 |
| » W: Byron McLaughlin (1-0) L: Nolan Ryan (0-1) | First | -- |
| Saturday, April 7 |
| » Lost to Angels (1-2), 5-4 | Kingdome (2-1) | 2-1 | |
| » W: Mark Clear (1-0) L: Rick Honeycutt (0-1) S: Dave LaRoche (1) | Third | ½ out |
| Sunday, April 8 |
| » Lost to Angels (2-2), 7-5 | Kingdome (2-2) | 2-2 | Lost 2 |
| » W: Dave LaRoche (1-0) L: Shane Rawley (0-1) | Third | 1½ out |
| Monday, April 9 |
| » Defeated Athletics (0-4), 5-2 | Kingdome (3-2) | 3-2 | |
| » W: Floyd Bannister (1-0) L: John Henry Johnson (0-1) S: Shane Rawley (1) | Fourth | 1 out |
| Tuesday, April 10 |
| » Defeated Athletics (0-5), 4-1 | Kingdome (4-2) | 4-2 | Won 2 |
| » W: Glenn Abbott (1-0) L: Rick Langford (0-2) S: Shane Rawley (2) | Fourth | 1 out |
| Wednesday, April 11 |
| » Lost to Athletics (1-5), 14-7 | Kingdome (4-3) | 4-3 | |
| » W: Jim Todd (1-1) L: Rick Honeycutt (0-2) | Third | 2 out |
| Thursday, April 12 |
| » Defeated Athletics (1-6), 4-3 | Kingdome (5-3) | 5-3 | |
| » W: John Montague (2-0) L: Bob Lacey (0-1) | Fourth | 2 out |
| Friday, April 13 |
| » Lost to Twins (5-2), 8-2 | Kingdome (5-4) | 5-4 | |
| » W: Geoff Zahn (2-0) L: Paul Mitchell (0-1) S: Mike Marshall (3) | Fifth | 2 out |
| Saturday, April 14 |
| » Lost to Twins (6-2), 6-5 | Kingdome (5-5) | 5-5 | Lost 2 |
| » W: Mike Marshall (2-0) L: Floyd Bannister (1-1) | Fifth | 3 out |
| Sunday, April 15 |
| » Lost to Twins (7-2), 18-6 | Kingdome (5-6) | 5-6 | Lost 3 |
| » W: Jerry Koosman (2-0) L: Glenn Abbott (1-1) | Fifth | 3 out |
| Monday, April 16 |
| » Lost to Athletics (2-9), 4-2 | Oakland-Alameda County Stadium (0-1) | 5-7 | Lost 4 |
| » W: Mike Norris (1-1) L: Shane Rawley (0-2) S: Bob Lacey (1) | Fifth | 3½ out |
| Tuesday, April 17 |
| » Lost to Athletics (3-9), 6-5 | Oakland-Alameda County Stadium (0-2) | 5-8 | Lost 5 |
| » W: Dave Heaverlo (1-0) L: Odell Jones (0-1) | Sixth | 4½ out |
| Wednesday, April 18 |
| » Lost to Athletics (4-9), 5-2 | Oakland-Alameda County Stadium (0-3) | 5-9 | Lost 6 |
| » W: Alan Wirth (1-0) L: Rick Honeycutt (0-3) S: Dave Heaverlo (1) | Sixth | 4½ out |
| Saturday, April 21 |
| » Lost to Twins (8-5), 6-5 | Metropolitan Stadium (0-1) | 5-10 | Lost 7 |
| » W: Jerry Koosman (3-0) L: Floyd Bannister (1-2) S: Mike Marshall (4) | Sixth | 7 out |
| Sunday, April 22 |
| » Lost to Twins (9-5), 3-1 | Metropolitan Stadium (0-2) | 5-11 | Lost 8 |
| » W: Dave Goltz (2-2) L: Glenn Abbott (1-2) | Sixth | 7 out |
| Tuesday, April 24 |
| » Lost to Red Sox (10-4), 4-3 | Kingdome (5-7) | 5-12 | Lost 9 |
| » W: Dick Drago (3-0) L: Shane Rawley (0-3) S: Bill Campbell (1) | Sixth | 7 out |
| Wednesday, April 25 |
| » Lost to Red Sox (11-4), 4-1 | Kingdome (5-8) | 5-13 | Lost 10 |
| » W: Jim Wright (1-0) L: Floyd Bannister (1-3) S: Chuck Rainey (1) | Seventh | 7 out |
| Thursday, April 26 |
| » Lost to Red Sox (12-4), 2-0 | Kingdome (5-9) | 5-14 | Lost 11 |
| » W: Bob Stanley (2-1) L: Paul Mitchell (0-2) | Seventh | 7 out |
| Friday, April 27 |
| » Defeated Yankees (10-8), 6-5 | Kingdome (6-9) | 6-14 | |
| » W: Mike Parrott (1-0) L: Dick Tidrow (1-1) S: Shane Rawley (3) | Seventh | 7 out |
| Saturday, April 28 |
| » Defeated Yankees (10-9), 3-2 | Kingdome (7-9) | 7-14 | Won 2 |
| » W: Shane Rawley (1-3) L: Catfish Hunter (0-2) S: John Montague (1) | Seventh | 7 out |
| Sunday, April 29 |
| » Defeated Yankees (10-10), 6-5 | Kingdome (8-9) | 8-14 | Won 3 |
| » W: Rafael Vasquez (1-0) L: Paul Mirabella (0-2) | Sixth | 6 out |
| Monday, April 30 |
| » Lost to Orioles (14-9), 8-7 | Kingdome (8-10) | 8-15 | |
| » W: Don Stanhouse (2-0) L: Rick Honeycutt (0-4) | Seventh | 7 out |
| Tuesday, May 1 |
| » Lost to Orioles (15-9), 3-1 | Kingdome (8-11) | 8-16 | Lost 2 |
| » W: Dennis Martinez (2-2) L: Byron McLaughlin (1-1) | Seventh | 7½ out |
| Wednesday, May 2 |
| » Lost to Orioles (16-9), 9-3 | Kingdome (8-12) | 8-17 | Lost 3 |
| » W: Mike Flanagan (4-2) L: Paul Mitchell (0-3) | Seventh | 8½ out |
| Friday, May 4 |
| » Lost to Red Sox (15-8), 5-3 | Fenway Park (0-1) | 8-18 | Lost 4 |
| » W: Steve Renko (2-1) L: Glenn Abbott (1-3) | Seventh | 10 out |
| Saturday, May 5 |
| » Lost to Red Sox (16-8), 11-4 | Fenway Park (0-2) | 8-19 | Lost 5 |
| » W: Dennis Eckersley (3-1) L: Odell Jones (0-2) S: Dick Drago (3) | Seventh | 10 out |
| Sunday, May 6 |
| » Defeated Red Sox (16-9), 3-2 | Fenway Park (1-2) | 9-19 | |
| » W: John Montague (3-0) L: Bill Campbell (0-1) | Seventh | 10 out |
| Monday, May 7 |
| » Defeated Yankees (13-14), 12-4 | Yankee Stadium (1-0) | 10-19 | Won 2 |
| » W: Rick Honeycutt (1-4) L: Paul Mirabella (0-3) | Seventh | 10 out |
| Tuesday, May 8 |
| » Lost to Yankees (14-14), 5-3 | Yankee Stadium (1-1) | 10-20 | |
| » W: Jim Beattie (1-1) L: Floyd Bannister (1-4) S: Ron Guidry (2) | Seventh | 11 out |
| Wednesday, May 9 |
| » Lost to Yankees (15-14), 5-0 | Yankee Stadium (1-2) | 10-21 | Lost 2 |
| » W: Ed Figueroa (3-3) L: Glenn Abbott (1-4) | Seventh | 11½ out |
| Thursday, May 10 |
| » Lost to Yankees (16-14), 8-1 | Yankee Stadium (1-3) | 10-22 | Lost 3 |
| » W: Tommy John (7-0) L: Odell Jones (0-3) | Seventh | 12 out |
| Friday, May 11 |
| » Lost to Orioles (21-11), 8-3 | Memorial Stadium (0-1) | 10-23 | Lost 4 |
| » W: Steve Stone (3-1) L: Byron McLaughlin (1-2) | Seventh | 13 out |
| Saturday, May 12 |
| » Lost to Orioles (22-11), 4-2 | Memorial Stadium (0-2) | 10-24 | Lost 5 |
| » W: Mike Flanagan (6-2) L: Rick Honeycutt (1-5) | Seventh | 14 out |
| Monday, May 14 |
| » Lost to Royals (19-15), 1-0 | Kingdome (8-13) | 10-25 | Lost 6 |
| » W: Rich Gale (3-2) L: Floyd Bannister (1-5) | Sixth | 13½ out |
| Tuesday, May 15 |
| » Lost to Royals (20-15), 7-4 | Kingdome (8-14) | 10-26 | Lost 7 |
| » W: Paul Splittorff (5-3) L: Glenn Abbott (1-5) S: Renie Martin (3) | Seventh | 13 out |
| » Defeated Royals (20-16), 6-2 | Kingdome (9-14) | 11-26 | |
| » W: Byron McLaughlin (2-2) L: Larry Gura (1-5) | Seventh | 13 out |
| Wednesday, May 16 |
| » Lost to Royals (21-16), 4-3 | Kingdome (9-15) | 11-27 | |
| » W: Steve Busby (1-2) L: Odell Jones (0-4) | Seventh | 13 out |
| Friday, May 18 |
| » Defeated Rangers (21-15), 13-5 | Kingdome (10-15) | 12-27 | |
| » W: John Montague (4-0) L: Steve Comer (3-4) | Seventh | 13½ out |
| Saturday, May 19 |
| » Defeated Rangers (21-16), 4-0 | Kingdome (11-15) | 13-27 | Won 2 |
| » W: Floyd Bannister (2-5) L: Fergie Jenkins (4-2) | Seventh | 13 out |
| Sunday, May 20 |
| » Lost to Rangers (22-16), 6-4 | Kingdome (11-16) | 13-28 | |
| » W: Doyle Alexander (2-2) L: Shane Rawley (1-4) S: Jim Kern (6) | Seventh | 13 out |
| Monday, May 21 |
| » Defeated Royals (22-19), 12-7 | Royals Stadium (1-0) | 14-28 | |
| » W: Glenn Abbott (2-5) L: Rich Gale (3-3) S: Shane Rawley (4) | Seventh | 13 out |
| Tuesday, May 22 |
| » Defeated Royals (22-20), 12-11 | Royals Stadium (2-0) | 15-28 | Won 2 |
| » W: Shane Rawley (2-4) L: Al Hrabosky (3-2) | Seventh | 12 out |
| Thursday, May 24 |
| » Lost to Royals (23-20), 5-4 | Royals Stadium (2-1) | 15-29 | |
| » W: Dennis Leonard (4-4) L: Odell Jones (0-5) | Sixth | 12 out |
| Friday, May 25 |
| » Defeated Rangers (24-18), 3-2 | Arlington Stadium (1-0) | 16-29 | |
| » W: Mike Parrott (2-0) L: Doyle Alexander (2-3) S: Shane Rawley (5) | Sixth | 10½ out |
| » Defeated Rangers (24-19), 5-3 | Arlington Stadium (2-0) | 17-29 | Won 2 |
| » W: Rick Honeycutt (2-5) L: Dock Ellis (1-3) | Sixth | 10½ out |
| Saturday, May 26 |
| » Lost to Rangers (25-19), 2-1 | Arlington Stadium (2-1) | 17-30 | |
| » W: Jon Matlack (3-2) L: Glenn Abbott (2-6) | Sixth | 10½ out |
| Sunday, May 27 |
| » Lost to Rangers (26-19), 7-3 | Arlington Stadium (2-2) | 17-31 | Lost 2 |
| » W: Steve Comer (4-4) L: Paul Mitchell (0-4) S: Jim Kern (7) | Sixth | 11½ out |
| Tuesday, May 29 |
| » Lost to Angels (29-19), 6-4 | Kingdome (11-17) | 17-32 | Lost 3 |
| » W: Jim Barr (3-0) L: Mike Parrott (2-1) S: Dave LaRoche (5) | Sixth | 12½ out |
| Wednesday, May 30 |
| » Lost to Angels (30-19), 3-2 | Kingdome (11-18) | 17-33 | Lost 4 |
| » W: Nolan Ryan (6-3) L: Shane Rawley (2-5) | Seventh | 13½ out |
| Thursday, May 31 |
| » Defeated Angels (30-20), 12-10 | Kingdome (12-18) | 18-33 | |
| » W: Byron McLaughlin (3-2) L: Mark Clear (4-1) S: Shane Rawley (6) | Sixth | 12½ out |
| Friday, June 1 |
| » Defeated Blue Jays (12-39), 7-2 | Kingdome (13-18) | 19-33 | Won 2 |
| » W: Paul Mitchell (1-4) L: Jesse Jefferson (0-5) | Sixth | 11½ out |
| Saturday, June 2 |
| » Lost to Blue Jays (13-39), 6-2 | Kingdome (13-19) | 19-34 | |
| » W: Dave Lemanczyk (5-3) L: Odell Jones (0-6) | Sixth | 12½ out |
| Sunday, June 3 |
| » Defeated Blue Jays (13-40), 10-5 | Kingdome (14-19) | 20-34 | |
| » W: Mike Parrott (3-1) L: Mark Lemongello (1-7) | Sixth | 11½ out |
| Monday, June 4 |
| » Defeated Tigers (24-23), 11-2 | Kingdome (15-19) | 21-34 | Won 2 |
| » W: Rick Honeycutt (3-5) L: Milt Wilcox (4-3) | Sixth | 11½ out |
| Tuesday, June 5 |
| » Lost to Tigers (25-23), 3-1 | Kingdome (15-20) | 21-35 | |
| » W: Jack Billingham (6-3) L: Glenn Abbott (2-7) S: John Hiller (5) | Sixth | 12½ out |
| Wednesday, June 6 |
| » Defeated Tigers (25-24), 4-3 | Kingdome (16-20) | 22-35 | |
| » W: Floyd Bannister (3-5) L: Jack Morris (3-2) S: Byron McLaughlin (1) | Sixth | 11½ out |
| Friday, June 8 |
| » Defeated Indians (26-28), 6-2 | Kingdome (17-20) | 23-35 | Won 2 |
| » W: Mike Parrott (4-1) L: Wayne Garland (2-7) S: Byron McLaughlin (2) | Sixth | 11½ out |
| Saturday, June 9 |
| » Lost to Indians (27-28), 4-3 | Kingdome (17-21) | 23-36 | |
| » W: Sid Monge (4-5) L: Shane Rawley (2-6) | Sixth | 12½ out |
| Sunday, June 10 |
| » Defeated Indians (27-29), 5-2 | Kingdome (18-21) | 24-36 | |
| » W: Odell Jones (1-6) L: Rick Waits (8-4) S: Shane Rawley (7) | Sixth | 11½ out |
| Monday, June 11 |
| » Lost to Blue Jays (17-43), 2-0 | Exhibition Stadium (0-1) | 24-37 | |
| » W: Dave Lemanczyk (6-3) L: Floyd Bannister (3-6) | Sixth | 12½ out |
| Tuesday, June 12 |
| » Defeated Blue Jays (17-44), 5-1 | Exhibition Stadium (1-1) | 25-37 | |
| » W: Glenn Abbott (3-7) L: Jesse Jefferson (1-6) | Sixth | 11½ out |
| Wednesday, June 13 |
| » Lost to Tigers (29-26), 7-3 | Tiger Stadium (0-1) | 25-38 | |
| » W: Milt Wilcox (5-4) L: Mike Parrott (4-2) S: John Hiller (7) | Sixth | 12 out |
| Thursday, June 14 |
| » Defeated Tigers (29-27), 3-2 | Tiger Stadium (1-1) | 26-38 | |
| » W: Shane Rawley (3-6) L: John Hiller (3-5) S: Byron McLaughlin (3) | Sixth | 12 out |
| Friday, June 15 |
| » Lost to Indians (31-30), 13-3 | Cleveland Stadium (0-1) | 26-39 | |
| » W: Rick Waits (9-4) L: Odell Jones (1-7) | Sixth | 13 out |
| Saturday, June 16 |
| » Lost to Indians (32-30), 4-3 | Cleveland Stadium (0-2) | 26-40 | Lost 2 |
| » W: Sid Monge (6-5) L: John Montague (4-1) | Sixth | 14 out |
| Sunday, June 17 |
| » Defeated Indians (32-31), 6-5 | Cleveland Stadium (1-2) | 27-40 | |
| » W: Shane Rawley (4-6) L: Sid Monge (6-6) S: Byron McLaughlin (4) | Sixth | 13 out |
| Monday, June 18 |
| » Defeated White Sox (31-33), 5-1 | Comiskey Park I (1-0) | 28-40 | Won 2 |
| » W: Mike Parrott (5-2) L: Ross Baumgarten (5-4) | Sixth | 13 out |
| Tuesday, June 19 |
| » Defeated White Sox (31-34), 7-2 | Comiskey Park I (2-0) | 29-40 | Won 3 |
| » W: Rick Honeycutt (4-5) L: Rich Wortham (7-6) S: Byron McLaughlin (5) | Sixth | 12 out |
| Wednesday, June 20 |
| » Defeated White Sox (31-35), 5-3 | Comiskey Park I (3-0) | 30-40 | Won 4 |
| » W: Odell Jones (2-7) L: Ed Farmer (2-1) S: Shane Rawley (8) | Sixth | 12 out |
| Thursday, June 21 |
| » Lost to White Sox (32-35), 9-5 | Comiskey Park I (3-1) | 30-41 | |
| » W: Francisco Barrios (7-3) L: Joe Decker (0-1) S: Rich Hinton (2) | Sixth | 12 out |
| Friday, June 22 |
| » Lost to Brewers (40-30), 15-8 | Kingdome (18-22) | 30-42 | Lost 2 |
| » W: Jim Slaton (7-3) L: Glenn Abbott (3-8) | Sixth | 12 out |
| Saturday, June 23 |
| » Defeated Brewers (40-31), 8-3 | Kingdome (19-22) | 31-42 | |
| » W: Mike Parrott (6-2) L: Lary Sorensen (9-7) | Sixth | 11 out |
| Sunday, June 24 |
| » Lost to Brewers (41-31), 7-4 | Kingdome (19-23) | 31-43 | |
| » W: Bill Castro (1-0) L: John Montague (4-2) | Fifth | 11 out |
| Tuesday, June 26 |
| » Defeated White Sox (32-40), 3-2 | Kingdome (20-23) | 32-43 | |
| » W: Byron McLaughlin (4-2) L: Steve Trout (1-3) S: Shane Rawley (9) | Fifth | 10 out |
| Wednesday, June 27 |
| » Defeated White Sox (32-41), 4-3 | Kingdome (21-23) | 33-43 | Won 2 |
| » W: Shane Rawley (5-6) L: Ken Kravec (8-6) | Fifth | 9 out |
| Thursday, June 28 |
| » Lost to White Sox (33-41), 2-1 | Kingdome (21-24) | 33-44 | |
| » W: Ross Baumgarten (6-5) L: Mike Parrott (6-3) S: Steve Trout (4) | Fifth | 10 out |
| Friday, June 29 |
| » Defeated Brewers (43-33), 3-2 | County Stadium (1-0) | 34-44 | |
| » W: Glenn Abbott (4-8) L: Lary Sorensen (9-8) S: Shane Rawley (10) | Sixth | 10 out |
| Saturday, June 30 |
| » Lost to Brewers (44-33), 8-1 | County Stadium (1-1) | 34-45 | |
| » W: Moose Haas (5-5) L: John Montague (4-3) | Sixth | 11 out |
| Sunday, July 1 |
| » Lost to Brewers (45-33), 10-3 | County Stadium (1-2) | 34-46 | Lost 2 |
| » W: Jim Slaton (8-3) L: Floyd Bannister (3-7) | Sixth | 11 out |
| Monday, July 2 |
| » Lost to Twins (41-34), 7-0 | Metropolitan Stadium (0-3) | 34-47 | Lost 3 |
| » W: Darrell Jackson (1-0) L: Odell Jones (2-8) | Sixth | 12 out |
| Tuesday, July 3 |
| » Lost to Twins (42-34), 12-2 | Metropolitan Stadium (0-4) | 34-48 | Lost 4 |
| » W: Pete Redfern (4-0) L: Mike Parrott (6-4) | Sixth | 12½ out |
| » Defeated Twins (42-35), 10-2 | Metropolitan Stadium (1-4) | 35-48 | |
| » W: Byron McLaughlin (5-2) L: Gary Serum (0-3) | Sixth | 12½ out |
| Wednesday, July 4 |
| » Lost to Twins (43-35), 7-2 | Metropolitan Stadium (1-5) | 35-49 | |
| » W: Jerry Koosman (10-6) L: Glenn Abbott (4-9) | Sixth | 13½ out |
| Thursday, July 5 |
| » Defeated Twins (43-36), 4-0 | Metropolitan Stadium (2-5) | 36-49 | |
| » W: Rick Honeycutt (5-5) L: Geoff Zahn (7-2) | Sixth | 13 out |
| Friday, July 6 |
| » Defeated Red Sox (50-30), 5-3 | Kingdome (22-24) | 37-49 | Won 2 |
| » W: Floyd Bannister (4-7) L: Dennis Eckersley (8-5) S: Byron McLaughlin (6) | Sixth | 12½ out |
| Saturday, July 7 |
| » Lost to Red Sox (51-30), 10-8 | Kingdome (22-25) | 37-50 | |
| » W: Tom Burgmeier (2-0) L: Mike Parrott (6-5) S: Allen Ripley (1) | Sixth | 13½ out |
| Sunday, July 8 |
| » Lost to Red Sox (52-30), 8-2 | Kingdome (22-26) | 37-51 | Lost 2 |
| » W: Steve Renko (7-3) L: Byron McLaughlin (5-3) | Sixth | 14 out |
| Tuesday, July 10 |
| » Defeated Yankees (48-39), 5-1 | Kingdome (23-26) | 38-51 | |
| » W: Rick Honeycutt (6-5) L: Ron Guidry (6-6) | Sixth | 14 out |
| Wednesday, July 11 |
| » Defeated Yankees (48-40), 16-1 | Kingdome (24-26) | 39-51 | Won 2 |
| » W: Floyd Bannister (5-7) L: Tommy John (13-4) | Sixth | 13 out |
| Thursday, July 12 |
| » Lost to Yankees (49-40), 14-2 | Kingdome (24-27) | 39-52 | |
| » W: Catfish Hunter (2-5) L: Mike Parrott (6-6) | Sixth | 13½ out |
| Friday, July 13 |
| » Defeated Orioles (57-31), 4-3 | Kingdome (25-27) | 40-52 | |
| » W: Odell Jones (3-8) L: Scott McGregor (3-3) | Sixth | 13½ out |
| Saturday, July 14 |
| » Lost to Orioles (58-31), 5-2 | Kingdome (25-28) | 40-53 | |
| » W: Mike Flanagan (12-6) L: Mike Parrott (6-7) | Sixth | 14½ out |
| Sunday, July 15 |
| » Lost to Orioles (59-31), 6-1 | Kingdome (25-29) | 40-54 | Lost 2 |
| » W: Dennis Martinez (12-6) L: Rick Honeycutt (6-6) | Sixth | 15½ out |
| Thursday, July 19 |
| » Lost to Red Sox (57-32), 7-1 | Fenway Park (1-3) | 40-55 | Lost 3 |
| » W: Dennis Eckersley (10-5) L: Floyd Bannister (5-8) | Sixth | 16 out |
| Friday, July 20 |
| » Defeated Red Sox (57-33), 8-0 | Fenway Park (2-3) | 41-55 | |
| » W: Mike Parrott (7-7) L: Mike Torrez (9-6) | Sixth | 15 out |
| Saturday, July 21 |
| » Defeated Red Sox (57-34), 13-5 | Fenway Park (3-3) | 42-55 | Won 2 |
| » W: John Montague (5-3) L: Steve Renko (8-4) S: Byron McLaughlin (7) | Sixth | 14 out |
| Sunday, July 22 |
| » Lost to Yankees (52-44), 4-0 | Yankee Stadium (1-4) | 42-56 | |
| » W: Jim Kaat (3-1) L: Rick Honeycutt (6-7) | Sixth | 14 out |
| Monday, July 23 |
| » Lost to Yankees (53-44), 6-2 | Yankee Stadium (1-5) | 42-57 | Lost 2 |
| » W: Ed Figueroa (4-6) L: Glenn Abbott (4-10) S: Rich Gossage (4) | Sixth | 15 out |
| Tuesday, July 24 |
| » Lost to Orioles (65-32), 7-6 | Memorial Stadium (0-3) | 42-58 | Lost 3 |
| » W: Dennis Martinez (13-7) L: Floyd Bannister (5-9) S: Don Stanhouse (13) | Sixth | 15½ out |
| » Lost to Orioles (66-32), 11-3 | Memorial Stadium (0-4) | 42-59 | Lost 4 |
| » W: Scott McGregor (5-3) L: Odell Jones (3-9) | Sixth | 15½ out |
| Wednesday, July 25 |
| » Defeated Orioles (66-33), 5-4 | Memorial Stadium (1-4) | 43-59 | |
| » W: Mike Parrott (8-7) L: Sammy Stewart (6-4) S: Byron McLaughlin (8) | Sixth | 15½ out |
| Thursday, July 26 |
| » Lost to Orioles (67-33), 12-1 | Memorial Stadium (1-5) | 43-60 | |
| » W: Steve Stone (8-7) L: Randy Stein (0-1) | Sixth | 15½ out |
| Friday, July 27 |
| » Defeated Athletics (27-76), 1-0 | Oakland-Alameda County Stadium (1-3) | 44-60 | |
| » W: Rick Honeycutt (7-7) L: Rick Langford (5-12) S: Byron McLaughlin (9) | Sixth | 14½ out |
| Saturday, July 28 |
| » Lost to Athletics (28-76), 6-5 | Oakland-Alameda County Stadium (1-4) | 44-61 | |
| » W: Dave Hamilton (3-4) L: Odell Jones (3-10) | Sixth | 15½ out |
| Sunday, July 29 |
| » Lost to Athletics (29-76), 2-1 | Oakland-Alameda County Stadium (1-5) | 44-62 | Lost 2 |
| » W: Mike Morgan (1-6) L: Floyd Bannister (5-10) | Sixth | 16½ out |
| Monday, July 30 |
| » Defeated Angels (60-46), 8-0 | Anaheim Stadium (1-0) | 45-62 | |
| » W: Mike Parrott (9-7) L: Jim Barr (7-7) | Sixth | 15½ out |
| Tuesday, July 31 |
| » Lost to Angels (61-46), 8-1 | Anaheim Stadium (1-1) | 45-63 | |
| » W: Dave Frost (9-7) L: Rob Dressler (0-1) | Sixth | 16½ out |
| Wednesday, August 1 |
| » Defeated Angels (61-47), 7-6 | Anaheim Stadium (2-1) | 46-63 | |
| » W: Randy Stein (1-1) L: Dave LaRoche (3-9) | Sixth | 15½ out |
| Friday, August 3 |
| » Defeated Athletics (31-78), 1-0 | Kingdome (26-29) | 47-63 | Won 2 |
| » W: Floyd Bannister (6-10) L: Matt Keough (0-13) | Sixth | 14½ out |
| Saturday, August 4 |
| » Lost to Athletics (32-78), 5-3 | Kingdome (26-30) | 47-64 | |
| » W: Mike Morgan (2-6) L: Mike Parrott (9-8) S: Dave Hamilton (2) | Sixth | 15½ out |
| Sunday, August 5 |
| » Lost to Athletics (33-78), 9-8 | Kingdome (26-31) | 47-65 | Lost 2 |
| » W: Brian Kingman (2-4) L: John Montague (5-4) S: Dave Hamilton (3) | Sixth | 16 out |
| Monday, August 6 |
| » Defeated Twins (57-52), 7-4 | Kingdome (27-31) | 48-65 | |
| » W: Rick Honeycutt (8-7) L: Darrell Jackson (2-3) S: Byron McLaughlin (10) | Sixth | 16 out |
| Tuesday, August 7 |
| » Lost to Twins (58-52), 5-2 | Kingdome (27-32) | 48-66 | |
| » W: Jerry Koosman (13-10) L: Rich Hinton (1-3) S: Mike Marshall (23) | Sixth | 16 out |
| Wednesday, August 8 |
| » Lost to Twins (59-52), 3-1 | Kingdome (27-33) | 48-67 | Lost 2 |
| » W: Dave Goltz (11-8) L: Floyd Bannister (6-11) S: Mike Marshall (24) | Sixth | 17 out |
| Friday, August 10 |
| » Defeated Angels (65-51), 8-6 | Anaheim Stadium (3-1) | 49-67 | |
| » W: Randy Stein (2-1) L: Dave LaRoche (4-10) | Sixth | 16 out |
| Saturday, August 11 |
| » Lost to Angels (66-51), 8-1 | Anaheim Stadium (3-2) | 49-68 | |
| » W: Jim Barr (8-9) L: Rick Honeycutt (8-8) | Sixth | 17 out |
| Sunday, August 12 |
| » Lost to Angels (67-51), 4-3 | Anaheim Stadium (3-3) | 49-69 | Lost 2 |
| » W: Dave Frost (12-7) L: Randy Stein (2-2) | Sixth | 18 out |
| Monday, August 13 |
| » Lost to Indians (60-58), 6-0 | Kingdome (27-34) | 49-70 | Lost 3 |
| » W: Rick Wise (13-6) L: Floyd Bannister (6-12) | Sixth | 18 out |
| Tuesday, August 14 |
| » Lost to Indians (61-58), 7-4 | Kingdome (27-35) | 49-71 | Lost 4 |
| » W: Rick Waits (12-10) L: Odell Jones (3-11) S: Sid Monge (16) | Sixth | 18 out |
| Wednesday, August 15 |
| » Defeated Indians (61-59), 3-2 | Kingdome (28-35) | 50-71 | |
| » W: Mike Parrott (10-8) L: Sid Monge (7-7) | Sixth | 17 out |
| Friday, August 17 |
| » Lost to Tigers (62-58), 9-2 | Kingdome (28-36) | 50-72 | |
| » W: Milt Wilcox (10-6) L: Rick Honeycutt (8-9) S: John Hiller (9) | Sixth | 17 out |
| Saturday, August 18 |
| » Lost to Tigers (63-58), 7-4 | Kingdome (28-37) | 50-73 | Lost 2 |
| » W: Jack Morris (11-5) L: Rob Dressler (0-2) | Sixth | 18 out |
| Sunday, August 19 |
| » Defeated Tigers (63-59), 8-4 | Kingdome (29-37) | 51-73 | |
| » W: Floyd Bannister (7-12) L: Bruce Robbins (2-2) | Sixth | 18 out |
| Monday, August 20 |
| » Defeated Blue Jays (39-85), 7-4 | Kingdome (30-37) | 52-73 | Won 2 |
| » W: Mike Parrott (11-8) L: Butch Edge (1-1) | Sixth | 18 out |
| Tuesday, August 21 |
| » Defeated Blue Jays (39-86), 8-4 | Kingdome (31-37) | 53-73 | Won 3 |
| » W: John Montague (6-4) L: Phil Huffman (5-14) S: Byron McLaughlin (11) | Sixth | 17 out |
| Wednesday, August 22 |
| » Defeated Blue Jays (39-87), 6-3 | Kingdome (32-37) | 54-73 | Won 4 |
| » W: Rick Honeycutt (9-9) L: Dave Stieb (5-4) | Sixth | 16 out |
| Friday, August 24 |
| » Lost to Tigers (66-60), 5-2 | Tiger Stadium (1-2) | 54-74 | |
| » W: Jack Morris (12-5) L: Floyd Bannister (7-13) S: Aurelio Lopez (14) | Sixth | 16 out |
| Saturday, August 25 |
| » Defeated Tigers (66-61), 8-4 | Tiger Stadium (2-2) | 55-74 | |
| » W: Mike Parrott (12-8) L: Dan Petry (5-4) | Sixth | 16 out |
| Sunday, August 26 |
| » Lost to Tigers (67-61), 4-3 | Tiger Stadium (2-3) | 55-75 | |
| » W: Aurelio Lopez (7-3) L: Byron McLaughlin (5-4) | Sixth | 16½ out |
| » Lost to Tigers (68-61), 9-8 | Tiger Stadium (2-4) | 55-76 | Lost 2 |
| » W: Dave Tobik (2-4) L: Randy Stein (2-3) | Sixth | 16½ out |
| Monday, August 27 |
| » Defeated Indians (66-65), 6-5 | Cleveland Stadium (2-2) | 56-76 | |
| » W: Byron McLaughlin (6-4) L: Victor Cruz (3-8) | Sixth | 15½ out |
| Wednesday, August 29 |
| » Lost to Indians (67-65), 5-4 | Cleveland Stadium (2-3) | 56-77 | |
| » W: Sid Monge (8-9) L: Shane Rawley (5-7) | Sixth | 15½ out |
| » Lost to Indians (68-65), 2-1 | Cleveland Stadium (2-4) | 56-78 | Lost 2 |
| » W: Rick Waits (14-11) L: Wayne Twitchell (5-4) S: Victor Cruz (10) | Sixth | 15½ out |
| Thursday, August 30 |
| » Defeated Blue Jays (42-91), 8-2 | Exhibition Stadium (2-1) | 57-78 | |
| » W: Mike Parrott (13-8) L: Balor Moore (3-6) | Sixth | 15 out |
| Friday, August 31 |
| » Lost to Blue Jays (43-91), 5-4 | Exhibition Stadium (2-2) | 57-79 | |
| » W: Tom Buskey (6-5) L: Byron McLaughlin (6-5) | Sixth | 15½ out |
| Saturday, September 1 |
| » Defeated Blue Jays (43-92), 3-2 | Exhibition Stadium (3-2) | 58-79 | |
| » W: Rick Honeycutt (10-9) L: Tom Buskey (6-6) | Sixth | 15½ out |
| Sunday, September 2 |
| » Lost to Blue Jays (44-92), 8-5 | Exhibition Stadium (3-3) | 58-80 | |
| » W: Dave Stieb (6-5) L: Wayne Twitchell (5-5) S: Jesse Jefferson (1) | Sixth | 16½ out |
| Monday, September 3 |
| » Lost to Rangers (67-71), 4-1 | Kingdome (32-38) | 58-81 | Lost 2 |
| » W: Doc Medich (7-6) L: Floyd Bannister (7-14) S: Jim Kern (23) | Sixth | 17½ out |
| Tuesday, September 4 |
| » Lost to Rangers (68-71), 5-2 | Kingdome (32-39) | 58-82 | Lost 3 |
| » W: Steve Comer (14-10) L: Mike Parrott (13-9) | Sixth | 17½ out |
| Wednesday, September 5 |
| » Defeated Rangers (68-72), 1-0 | Kingdome (33-39) | 59-82 | |
| » W: Rob Dressler (1-2) L: Fergie Jenkins (13-12) S: Byron McLaughlin (12) | Sixth | 17½ out |
| Friday, September 7 |
| » Lost to Royals (74-66), 6-2 | Kingdome (33-40) | 59-83 | |
| » W: Craig Chamberlain (4-1) L: Rick Honeycutt (10-10) | Sixth | 19 out |
| Saturday, September 8 |
| » Defeated Royals (74-67), 4-2 | Kingdome (34-40) | 60-83 | |
| » W: Floyd Bannister (8-14) L: Dennis Leonard (11-10) | Sixth | 19 out |
| Sunday, September 9 |
| » Lost to Royals (75-67), 3-1 | Kingdome (34-41) | 60-84 | |
| » W: Larry Gura (11-10) L: Mike Parrott (13-10) | Sixth | 20 out |
| Monday, September 10 |
| » Defeated Rangers (71-73), 5-2 | Arlington Stadium (3-2) | 61-84 | |
| » W: Rob Dressler (2-2) L: Fergie Jenkins (13-13) S: Byron McLaughlin (13) | Sixth | 19½ out |
| Tuesday, September 11 |
| » Lost to Rangers (72-73), 5-2 | Arlington Stadium (3-3) | 61-85 | |
| » W: Doyle Alexander (4-6) L: Roy Branch (0-1) S: Sparky Lyle (11) | Sixth | 19½ out |
| Wednesday, September 12 |
| » Lost to Rangers (73-73), 13-3 | Arlington Stadium (3-4) | 61-86 | Lost 2 |
| » W: Doc Medich (9-6) L: Rick Honeycutt (10-11) | Sixth | 19½ out |
| Friday, September 14 |
| » Defeated Royals (77-70), 7-5 | Royals Stadium (3-1) | 62-86 | |
| » W: Floyd Bannister (9-14) L: Larry Gura (11-11) S: Byron McLaughlin (14) | Sixth | 19½ out |
| Saturday, September 15 |
| » Lost to Royals (78-70), 5-4 | Royals Stadium (3-2) | 62-87 | |
| » W: Al Hrabosky (9-4) L: Byron McLaughlin (6-6) | Sixth | 19½ out |
| Sunday, September 16 |
| » Defeated Royals (78-71), 6-3 | Royals Stadium (4-2) | 63-87 | |
| » W: Rob Dressler (3-2) L: Paul Splittorff (13-17) | Sixth | 18½ out |
| Monday, September 17 |
| » Lost to Brewers (88-62), 7-6 | Kingdome (34-42) | 63-88 | |
| » W: Bill Travers (13-8) L: Rich Hinton (1-4) S: Bob McClure (4) | Sixth | 18½ out |
| Tuesday, September 18 |
| » Lost to Brewers (89-62), 7-6 | Kingdome (34-43) | 63-89 | Lost 2 |
| » W: Jerry Augustine (7-6) L: Shane Rawley (5-8) S: Bill Castro (6) | Sixth | 19½ out |
| Wednesday, September 19 |
| » Lost to Brewers (90-62), 12-1 | Kingdome (34-44) | 63-90 | Lost 3 |
| » W: Lary Sorensen (15-13) L: Floyd Bannister (9-15) | Sixth | 19½ out |
| Friday, September 21 |
| » Lost to White Sox (68-83), 7-4 | Kingdome (34-45) | 63-91 | Lost 4 |
| » W: Steve Trout (10-8) L: Mike Parrott (13-11) S: Ed Farmer (13) | Sixth | 20 out |
| Saturday, September 22 |
| » Defeated White Sox (68-84), 6-4 | Kingdome (35-45) | 64-91 | |
| » W: Byron McLaughlin (7-6) L: Guy Hoffman (0-5) | Fifth | 20 out |
| Sunday, September 23 |
| » Defeated White Sox (68-85), 8-3 | Kingdome (36-45) | 65-91 | Won 2 |
| » W: Rick Honeycutt (11-11) L: Rich Wortham (14-13) | Sixth | 20 out |
| Tuesday, September 25 |
| » Lost to Brewers (92-64), 7-6 | County Stadium (1-3) | 65-92 | |
| » W: Jerry Augustine (9-6) L: Shane Rawley (5-9) | Sixth | 21½ out |
| Wednesday, September 26 |
| » Defeated Brewers (92-65), 8-1 | County Stadium (2-3) | 66-92 | |
| » W: Mike Parrott (14-11) L: Moose Haas (11-11) | Sixth | 20½ out |
| Thursday, September 27 |
| » |