| Friday, January 5 |
| Future Cub Ruben Quevedo is born in Valencia Carabobo, Venezuela. |
| Wednesday, February 7 |
| Future Cub Jon Leicester is born in Mariposa, CA. |
| Friday, March 16 |
| Future Cub Hee Seop Choi is born in Chun-Nam, South Korea. |
| Sunday, March 18 |
| Former Cub Percy Jones dies in Dallas, TX at the age of 80. |
| Monday, March 26 |
| Future Cub Jason Dubois is born in Virginia Beach, VA. |
| Saturday, March 31 |
| Former Cub Bob Schultz dies in Nashville, TN at the age of 56. |
| Wednesday, April 4 |
| » Major-league debuts: Mark Clear (Angels) |
| Thursday, April 5 |
| » Lost to Mets (1-0), 10-6 | Wrigley Field (0-1) | 0-1 | |
| » W: Craig Swan (1-0) L: Rick Reuschel (0-1) | Third | 1 out |
| » Major-league debuts: Kelvin Chapman and Jesse Orosco (Mets) |
| Saturday, April 7 |
| » Lost to Mets (2-0), 9-4 | Wrigley Field (0-2) | 0-2 | Lost 2 |
| » W: Pat Zachry (1-0) L: Ken Holtzman (0-1) S: Skip Lockwood (1) | Third | 2 out |
| Tuesday, April 10 |
| » Lost to Cardinals (3-0), 7-0 | Busch Stadium II (0-1) | 0-3 | Lost 3 |
| » W: Bob Sykes (1-0) L: Lynn McGlothen (0-1) | Sixth | 3 out |
| Saturday, April 14 |
| » Lost to Expos (5-1), 2-0 | Stade Olympique (0-1) | 0-4 | Lost 4 |
| » W: Ross Grimsley (1-0) L: Rick Reuschel (0-2) S: Elias Sosa (1) | Sixth | 4 out |
| Sunday, April 15 |
| » Defeated Expos (5-2), 5-1 | Stade Olympique (1-1) | 1-4 | |
| » W: Lynn McGlothen (1-1) L: Steve Rogers (0-1) | Fifth | 3 out |
| Monday, April 16 |
| » Lost to Expos (6-2), 2-0 | Stade Olympique (1-2) | 1-5 | |
| » W: Bill Lee (1-0) L: Mike Krukow (0-1) | Fifth | 4 out |
| Tuesday, April 17 |
| » Defeated Cardinals (4-4), 5-3 | Wrigley Field (1-2) | 2-5 | |
| » W: Ken Holtzman (1-1) L: John Denny (1-2) S: Bruce Sutter (1) | Sixth | 4 out |
| Wednesday, April 18 |
| » Lost to Cardinals (5-4), 3-2 | Wrigley Field (1-3) | 2-6 | |
| » W: Tom Bruno (1-0) L: Donnie Moore (0-1) S: Darold Knowles (1) | Sixth | 5 out |
| Thursday, April 19 |
| » Defeated Cardinals (5-5), 3-2 | Wrigley Field (2-3) | 3-6 | |
| » W: Dennis Lamp (1-0) L: Bob Forsch (0-2) S: Bruce Sutter (2) | Fifth | 4½ out |
| Friday, April 20 |
| » Defeated Expos (8-3), 8-5 | Wrigley Field (3-3) | 4-6 | Won 2 |
| » W: Lynn McGlothen (2-1) L: Woodie Fryman (1-1) S: Bruce Sutter (3) | Fourth | 3½ out |
| Saturday, April 21 |
| » Defeated Expos (8-4), 4-3 | Wrigley Field (4-3) | 5-6 | Won 3 |
| » W: Donnie Moore (1-1) L: David Palmer (2-1) S: Bruce Sutter (4) | Third | 3 out |
| Sunday, April 22 |
| » Defeated Expos (8-5), 4-1 | Wrigley Field (5-3) | 6-6 | Won 4 |
| » W: Rick Reuschel (1-2) L: Scott Sanderson (0-1) | Third | 2 out |
| Wednesday, April 25 |
| » Defeated Astros (12-5), 4-0 | Wrigley Field (6-3) | 7-6 | Won 5 |
| » W: Dennis Lamp (2-0) L: Vern Ruhle (1-3) | Third | 3 out |
| Thursday, April 26 |
| » Lost to Astros (13-5), 6-2 | Wrigley Field (6-4) | 7-7 | |
| » W: J.R. Richard (4-0) L: Lynn McGlothen (2-2) S: Joe Sambito (3) | Fourth | 3½ out |
| Friday, April 27 |
| » Lost to Braves (6-12), 3-2 | Atlanta-Fulton County Stadium (0-1) | 7-8 | Lost 2 |
| » W: Phil Niekro (2-4) L: Donnie Moore (1-2) | Fourth | 4½ out |
| Saturday, April 28 |
| » Lost to Braves (7-12), 7-2 | Atlanta-Fulton County Stadium (0-2) | 7-9 | Lost 3 |
| » W: Rick Matula (2-2) L: Rick Reuschel (1-3) S: Gene Garber (4) | Third | 4½ out |
| Sunday, April 29 |
| » Defeated Braves (7-13), 6-5 | Atlanta-Fulton County Stadium (1-2) | 8-9 | |
| » W: Lynn McGlothen (3-2) L: Gene Garber (1-3) S: Bruce Sutter (5) | Third | 4½ out |
| Tuesday, May 1 |
| » Defeated Reds (11-11), 5-1 | Riverfront Stadium (1-0) | 9-9 | Won 2 |
| » W: Ken Holtzman (2-1) L: Fred Norman (1-3) | Third | 5 out |
| Wednesday, May 2 |
| » Lost to Reds (12-11), 4-1 | Riverfront Stadium (1-1) | 9-10 | |
| » W: Mike LaCoss (2-0) L: Rick Reuschel (1-4) S: Doug Bair (4) | Fourth | 5½ out |
| Friday, May 4 |
| » Defeated Braves (8-15), 6-2 | Wrigley Field (7-4) | 10-10 | |
| » W: Mike Krukow (1-1) L: Rick Matula (2-3) S: Lynn McGlothen (1) | Fourth | 5 out |
| Saturday, May 5 |
| » Defeated Braves (8-16), 9-3 | Wrigley Field (8-4) | 11-10 | Won 2 |
| » W: Dennis Lamp (3-0) L: Phil Niekro (3-5) | Second | 4 out |
| Former Cub Virgil Cheeves dies in Dallas, TX at the age of 79. |
| Sunday, May 6 |
| » Defeated Braves (8-17), 14-13 | Wrigley Field (9-4) | 12-10 | Won 3 |
| » W: Bruce Sutter (1-0) L: Gene Garber (1-4) | Second | 4 out |
| Tuesday, May 8 |
| » Lost to Reds (16-12), 8-7 | Wrigley Field (9-5) | 12-11 | |
| » W: Mike LaCoss (3-0) L: Ken Holtzman (2-2) S: Frank Pastore (4) | Fourth | 5½ out |
| Wednesday, May 9 |
| » Lost to Reds (17-12), 7-4 | Wrigley Field (9-6) | 12-12 | Lost 2 |
| » W: Paul Moskau (2-0) L: Lynn McGlothen (3-3) S: Doug Bair (5) | Fourth | 6½ out |
| Thursday, May 10 |
| » Defeated Reds (17-13), 9-8 | Wrigley Field (10-6) | 13-12 | |
| » W: Lynn McGlothen (4-3) L: Manny Sarmiento (0-1) | Fourth | 6½ out |
| Friday, May 11 |
| » Defeated Astros (18-14), 5-3 | Astrodome (1-0) | 14-12 | Won 2 |
| » W: Rick Reuschel (2-4) L: Frank Riccelli (2-2) S: Bruce Sutter (6) | Third | 5½ out |
| Saturday, May 12 |
| » Lost to Astros (19-14), 11-3 | Astrodome (1-1) | 14-13 | |
| » W: Ken Forsch (4-2) L: Lynn McGlothen (4-4) | Third | 5 out |
| » Defeated Astros (19-15), 2-0 | Astrodome (2-1) | 15-13 | |
| » W: Ken Holtzman (3-2) L: Rick Williams (0-1) | Third | 5 out |
| » Major-league debuts: Bill Caudill (Cubs) |
| Sunday, May 13 |
| » Lost to Astros (20-15), 3-0 | Astrodome (2-2) | 15-14 | |
| » W: Joe Niekro (3-2) L: Mike Krukow (1-2) | Fourth | 6 out |
| Tuesday, May 15 |
| » Defeated Phillies (22-10), 7-1 | Wrigley Field (11-6) | 16-14 | |
| » W: Lynn McGlothen (5-4) L: Nino Espinosa (5-2) | Fourth | 5 out |
| Wednesday, May 16 |
| » Lost to Phillies (23-10), 13-0 | Wrigley Field (11-7) | 16-15 | |
| » W: Steve Carlton (4-5) L: Rick Reuschel (2-5) | Fourth | 6 out |
| Thursday, May 17 |
| » Lost to Phillies (24-10), 23-22 | Wrigley Field (11-8) | 16-16 | Lost 2 |
| » W: Rawly Eastwick (1-0) L: Bruce Sutter (1-1) | Fourth | 7 out |
| Friday, May 18 |
| » Lost to Pirates (15-18), 9-5 | Wrigley Field (11-9) | 16-17 | Lost 3 |
| » W: John Candelaria (3-2) L: Ken Holtzman (3-3) | Fourth | 7 out |
| Saturday, May 19 |
| » Lost to Pirates (16-18), 3-0 | Wrigley Field (11-10) | 16-18 | Lost 4 |
| » W: Jim Rooker (1-0) L: Mike Krukow (1-3) S: Grant Jackson (5) | Fourth | 7 out |
| Sunday, May 20 |
| » Lost to Pirates (17-18), 6-5 | Wrigley Field (11-11) | 16-19 | Lost 5 |
| » W: Don Robinson (3-3) L: Lynn McGlothen (5-5) S: Kent Tekulve (3) | Fifth | 7 out |
| Tuesday, May 22 |
| » Lost to Mets (13-23), 4-2 | Shea Stadium (0-1) | 16-20 | Lost 6 |
| » W: Kevin Kobel (2-0) L: Dennis Lamp (3-1) S: Dale Murray (1) | Fifth | 8½ out |
| Thursday, May 24 |
| » Defeated Mets (13-24), 9-7 | Shea Stadium (1-1) | 17-20 | |
| » W: Ken Holtzman (4-3) L: Pete Falcone (0-4) S: Bruce Sutter (7) | Fifth | 8 out |
| » Lost to Mets (14-24), 4-2 | Shea Stadium (1-2) | 17-21 | |
| » W: Pat Zachry (3-0) L: Mike Krukow (1-4) S: Skip Lockwood (7) | Fifth | 8 out |
| Friday, May 25 |
| » Defeated Phillies (26-15), 3-0 | Veteran's Stadium (1-0) | 18-21 | |
| » W: Lynn McGlothen (6-5) L: Nino Espinosa (5-4) S: Bruce Sutter (8) | Fifth | 7 out |
| Saturday, May 26 |
| » Defeated Phillies (26-16), 4-1 | Veteran's Stadium (2-0) | 19-21 | Won 2 |
| » W: Dennis Lamp (4-1) L: Larry Christenson (0-1) S: Dick Tidrow (3) | Fourth | 6½ out |
| Sunday, May 27 |
| » Lost to Phillies (27-16), 6-4 | Veteran's Stadium (2-1) | 19-22 | |
| » W: Steve Carlton (6-5) L: Bill Caudill (0-1) | Fifth | 7 out |
| Monday, May 28 |
| » Defeated Phillies (27-17), 4-1 | Veteran's Stadium (3-1) | 20-22 | |
| » W: Dick Tidrow (3-1) L: Randy Lerch (2-3) S: Bruce Sutter (9) | Fifth | 6½ out |
| Tuesday, May 29 |
| » Lost to Pirates (21-21), 8-0 | Three Rivers Stadium (0-1) | 20-23 | |
| » W: Don Robinson (4-3) L: Ken Holtzman (4-4) | Fifth | 7½ out |
| Wednesday, May 30 |
| » Lost to Pirates (22-21), 9-2 | Three Rivers Stadium (0-2) | 20-24 | Lost 2 |
| » W: Jim Rooker (2-0) L: Lynn McGlothen (6-6) | Fifth | 8½ out |
| Thursday, May 31 |
| » Lost to Pirates (23-21), 4-3 | Three Rivers Stadium (0-3) | 20-25 | Lost 3 |
| » W: Bruce Kison (2-1) L: Bruce Sutter (1-2) | Fifth | 9½ out |
| Friday, June 1 |
| » Defeated Giants (25-27), 8-2 | Wrigley Field (12-11) | 21-25 | |
| » W: Rick Reuschel (3-5) L: Philip Nastu (2-4) | Fifth | 8½ out |
| Saturday, June 2 |
| » Lost to Giants (26-27), 8-6 | Wrigley Field (12-12) | 21-26 | |
| » W: Randy Moffitt (1-2) L: Dick Tidrow (3-2) S: Gary Lavelle (7) | Fifth | 8½ out |
| Sunday, June 3 |
| » Defeated Giants (26-28), 2-1 | Wrigley Field (13-12) | 22-26 | |
| » W: Mike Krukow (2-4) L: John Curtis (1-2) S: Bruce Sutter (10) | Fifth | 7½ out |
| Tuesday, June 5 |
| » Lost to Padres (26-31), 11-3 | Wrigley Field (13-13) | 22-27 | |
| » W: Eric Rasmussen (3-5) L: Dennis Lamp (4-2) | Fifth | 8 out |
| Wednesday, June 6 |
| » Defeated Padres (26-32), 3-0 | Wrigley Field (14-13) | 23-27 | |
| » W: Rick Reuschel (4-5) L: Randy Jones (5-4) S: Bruce Sutter (11) | Fifth | 8 out |
| Thursday, June 7 |
| » Defeated Padres (26-33), 4-3 | Wrigley Field (15-13) | 24-27 | Won 2 |
| » W: Lynn McGlothen (7-6) L: Bob Shirley (2-6) S: Bruce Sutter (12) | Fifth | 7½ out |
| Friday, June 8 |
| » Lost to Dodgers (28-31), 11-4 | Wrigley Field (15-14) | 24-28 | |
| » W: Burt Hooton (5-3) L: Mike Krukow (2-5) | Fifth | 7½ out |
| Saturday, June 9 |
| » Defeated Dodgers (28-32), 5-3 | Wrigley Field (16-14) | 25-28 | |
| » W: Dennis Lamp (5-2) L: Rick Sutcliffe (6-4) S: Dick Tidrow (4) | Fifth | 6½ out |
| Sunday, June 10 |
| » Defeated Dodgers (28-33), 10-3 | Wrigley Field (17-14) | 26-28 | Won 2 |
| » W: Rick Reuschel (5-5) L: Don Sutton (6-6) S: Lynn McGlothen (2) | Fourth | 5½ out |
| Tuesday, June 12 |
| » Lost to Giants (30-31), 7-2 | Candlestick Park (0-1) | 26-29 | |
| » W: Bob Knepper (6-2) L: Ken Holtzman (4-5) | Fifth | 6½ out |
| Wednesday, June 13 |
| » Defeated Giants (30-32), 3-2 | Candlestick Park (1-1) | 27-29 | |
| » W: Bruce Sutter (2-2) L: Randy Moffitt (1-5) | Fifth | 6½ out |
| Thursday, June 14 |
| » Defeated Giants (30-33), 8-6 | Candlestick Park (2-1) | 28-29 | Won 2 |
| » W: Dick Tidrow (4-2) L: Gary Lavelle (4-3) S: Bruce Sutter (13) | Fifth | 6½ out |
| Friday, June 15 |
| » Defeated Padres (30-36), 3-2 | San Diego/Jack Murphy Stadium (1-0) | 29-29 | Won 3 |
| » W: Willie Hernandez (1-0) L: John D'Acquisto (3-5) S: Dick Tidrow (5) | Fifth | 5½ out |
| Saturday, June 16 |
| » Defeated Padres (30-37), 5-2 | San Diego/Jack Murphy Stadium (2-0) | 30-29 | Won 4 |
| » W: Ken Holtzman (5-5) L: Gaylord Perry (6-5) S: Bruce Sutter (14) | Fifth | 5½ out |
| Sunday, June 17 |
| » Defeated Padres (30-38), 8-5 | San Diego/Jack Murphy Stadium (3-0) | 31-29 | Won 5 |
| » W: Mike Krukow (3-5) L: Bob Owchinko (3-3) S: Bruce Sutter (15) | Fifth | 5½ out |
| Monday, June 18 |
| » Lost to Dodgers (31-37), 7-3 | Dodger Stadium (0-1) | 31-30 | |
| » W: Burt Hooton (7-3) L: Dennis Lamp (5-3) | Fifth | 5½ out |
| Tuesday, June 19 |
| » Defeated Dodgers (31-38), 7-4 | Dodger Stadium (1-1) | 32-30 | |
| » W: Dick Tidrow (5-2) L: Rick Sutcliffe (7-5) S: Bruce Sutter (16) | Fifth | 5½ out |
| Friday, June 22 |
| » Lost to Pirates (34-28), 7-2 | Three Rivers Stadium (0-4) | 32-31 | |
| » W: Bert Blyleven (4-2) L: Ken Holtzman (5-6) | Fifth | 7 out |
| Saturday, June 23 |
| » Defeated Pirates (34-29), 4-3 | Three Rivers Stadium (1-4) | 33-31 | |
| » W: Mike Krukow (4-5) L: Don Robinson (5-4) S: Bruce Sutter (17) | Third | 7 out |
| Sunday, June 24 |
| » Defeated Pirates (34-30), 5-0 | Three Rivers Stadium (2-4) | 34-31 | Won 2 |
| » W: Rick Reuschel (6-5) L: Bruce Kison (3-4) | Third | 6 out |
| Monday, June 25 |
| » Defeated Phillies (36-34), 8-2 | Wrigley Field (18-14) | 35-31 | Won 3 |
| » W: Lynn McGlothen (8-6) L: Steve Carlton (8-8) | Second | 6 out |
| Tuesday, June 26 |
| » Lost to Phillies (37-34), 5-3 | Wrigley Field (18-15) | 35-32 | |
| » W: Dick Ruthven (7-4) L: Donnie Moore (1-3) S: Tug McGraw (6) | Third | 7 out |
| Wednesday, June 27 |
| » Defeated Phillies (37-35), 11-4 | Wrigley Field (19-15) | 36-32 | |
| » W: Mike Krukow (5-5) L: Randy Lerch (4-6) | Second | 6 out |
| Saturday, June 30 |
| » Lost to Mets (31-39), 9-8 | Wrigley Field (19-16) | 36-33 | |
| » W: Wayne Twitchell (3-0) L: Dick Tidrow (5-3) S: Ed Glynn (4) | Second | 6½ out |
| Sunday, July 1 |
| » Defeated Mets (31-40), 5-4 | Wrigley Field (20-16) | 37-33 | |
| » W: Dick Tidrow (6-3) L: Wayne Twitchell (3-1) | Second | 5½ out |
| » Defeated Mets (31-41), 8-2 | Wrigley Field (21-16) | 38-33 | Won 2 |
| » W: Lynn McGlothen (9-6) L: Pete Falcone (1-6) | Second | 5½ out |
| Monday, July 2 |
| » Lost to Expos (44-27), 5-0 | Wrigley Field (21-17) | 38-34 | |
| » W: Steve Rogers (8-5) L: Dennis Lamp (5-4) | Second | 6½ out |
| Former Cub Ed Stauffer dies in St.Petersburg, FL at the age of 82. |
| Tuesday, July 3 |
| » Defeated Expos (44-28), 3-2 | Wrigley Field (22-17) | 39-34 | |
| » W: Bruce Sutter (3-2) L: Woodie Fryman (2-3) | Second | 5½ out |
| Wednesday, July 4 |
| » Lost to Expos (45-28), 2-1 | Wrigley Field (22-18) | 39-35 | |
| » W: Bill Lee (8-5) L: Bill Caudill (0-2) S: Elias Sosa (8) | Third | 6½ out |
| Thursday, July 5 |
| » Defeated Expos (45-29), 3-1 | Wrigley Field (23-18) | 40-35 | |
| » W: Rick Reuschel (7-5) L: Scott Sanderson (5-5) S: Bruce Sutter (18) | Second | 5½ out |
| Friday, July 6 |
| » Lost to Astros (53-32), 4-2 | Wrigley Field (23-19) | 40-36 | |
| » W: Joe Niekro (13-3) L: Lynn McGlothen (9-7) S: Joe Sambito (10) | Third | 6½ out |
| Saturday, July 7 |
| » Defeated Astros (53-33), 6-0 | Wrigley Field (24-19) | 41-36 | |
| » W: Ken Holtzman (6-6) L: Rick Williams (3-4) | Second | 6 out |
| » Defeated Astros (53-34), 8-3 | Wrigley Field (25-19) | 42-36 | Won 2 |
| » W: Dennis Lamp (6-4) L: Randy Niemann (3-1) | Second | 6 out |
| Sunday, July 8 |
| » Defeated Astros (53-35), 10-0 | Wrigley Field (26-19) | 43-36 | Won 3 |
| » W: Mike Krukow (6-5) L: Ken Forsch (5-4) S: Donnie Moore (1) | Second | 5 out |
| Monday, July 9 |
| » Defeated Braves (37-50), 7-4 | Atlanta-Fulton County Stadium (2-2) | 44-36 | Won 4 |
| » W: Dick Tidrow (7-3) L: Phil Niekro (11-11) S: Bruce Sutter (19) | Second | 5 out |
| Tuesday, July 10 |
| » Defeated Braves (37-51), 7-3 | Atlanta-Fulton County Stadium (3-2) | 45-36 | Won 5 |
| » W: Rick Reuschel (8-5) L: Eddie Solomon (4-5) S: Bruce Sutter (20) | Second | 4 out |
| Wednesday, July 11 |
| » Lost to Braves (38-51), 6-5 | Atlanta-Fulton County Stadium (3-3) | 45-37 | |
| » W: Tony Brizzolara (5-3) L: Lynn McGlothen (9-8) S: Gene Garber (18) | Second | 4 out |
| Thursday, July 12 |
| » Defeated Reds (47-44), 10-8 | Riverfront Stadium (2-1) | 46-37 | |
| » W: Bruce Sutter (4-2) L: Doug Bair (5-5) | Second | 3 out |
| Friday, July 13 |
| » Defeated Reds (47-45), 3-1 | Riverfront Stadium (3-1) | 47-37 | Won 2 |
| » W: Dennis Lamp (7-4) L: Fred Norman (5-8) S: Bruce Sutter (21) | Second | 2½ out |
| Saturday, July 14 |
| » Defeated Reds (47-46), 1-0 | Riverfront Stadium (4-1) | 48-37 | Won 3 |
| » W: Mike Krukow (7-5) L: Bill Bonham (3-4) S: Bruce Sutter (22) | Second | 1½ out |
| Sunday, July 15 |
| » Lost to Reds (48-46), 7-1 | Riverfront Stadium (4-2) | 48-38 | |
| » W: Tom Seaver (9-5) L: Rick Reuschel (8-6) | Second | 2½ out |
| Thursday, July 19 |
| » Lost to Braves (40-53), 8-2 | Wrigley Field (26-20) | 48-39 | Lost 2 |
| » W: Phil Niekro (13-11) L: Dennis Lamp (7-5) | Second | 2½ out |
| Friday, July 20 |
| » Defeated Braves (40-54), 10-2 | Wrigley Field (27-20) | 49-39 | |
| » W: Rick Reuschel (9-6) L: Tony Brizzolara (5-4) | Second | 1½ out |
| Saturday, July 21 |
| » Defeated Braves (40-55), 3-2 | Wrigley Field (28-20) | 50-39 | Won 2 |
| » W: Dick Tidrow (8-3) L: Gene Garber (5-11) | Second | 1½ out |
| Sunday, July 22 |
| » Lost to Reds (51-47), 12-1 | Wrigley Field (28-21) | 50-40 | |
| » W: Bill Bonham (4-4) L: Ken Holtzman (6-7) | Third | 1½ out |
| » Defeated Reds (51-48), 8-4 | Wrigley Field (29-21) | 51-40 | |
| » W: Dick Tidrow (9-3) L: Mario Soto (0-2) | Third | 1½ out |
| Monday, July 23 |
| » Defeated Reds (51-49), 2-1 | Wrigley Field (30-21) | 52-40 | Won 2 |
| » W: Willie Hernandez (2-0) L: Tom Hume (6-6) | Third | 1½ out |
| Tuesday, July 24 |
| » Lost to Astros (57-44), 6-1 | Astrodome (2-3) | 52-41 | |
| » W: Ken Forsch (6-6) L: Dennis Lamp (7-6) | Third | 1½ out |
| Wednesday, July 25 |
| » Lost to Astros (58-44), 6-4 | Astrodome (2-4) | 52-42 | Lost 2 |
| » W: J.R. Richard (8-11) L: Rick Reuschel (9-7) S: Joe Sambito (12) | Third | 2½ out |
| Thursday, July 26 |
| » Defeated Mets (41-54), 9-2 | Shea Stadium (2-2) | 53-42 | |
| » W: Mike Krukow (8-5) L: Tom Hausman (1-5) | Second | 2 out |
| Friday, July 27 |
| » Defeated Mets (41-55), 4-2 | Shea Stadium (3-2) | 54-42 | Won 2 |
| » W: Dick Tidrow (10-3) L: Dock Ellis (2-8) S: Bruce Sutter (23) | Second | ½ out |
| Saturday, July 28 |
| » Lost to Mets (42-55), 6-4 | Shea Stadium (3-3) | 54-43 | |
| » W: Pete Falcone (2-7) L: Ken Holtzman (6-8) S: Neil Allen (1) | Third | 1 out |
| Sunday, July 29 |
| » Lost to Mets (43-55), 4-0 | Shea Stadium (3-4) | 54-44 | Lost 2 |
| » W: Kevin Kobel (5-5) L: Dennis Lamp (7-7) S: Ed Glynn (5) | Third | 1½ out |
| Monday, July 30 |
| » Lost to Phillies (53-49), 5-4 | Veteran's Stadium (3-2) | 54-45 | Lost 3 |
| » W: Ron Reed (7-6) L: Bruce Sutter (4-3) | Third | 2 out |
| Tuesday, July 31 |
| » Lost to Phillies (54-49), 4-1 | Veteran's Stadium (3-3) | 54-46 | Lost 4 |
| » W: Nino Espinosa (11-8) L: Mike Krukow (8-6) | Third | 3 out |
| Wednesday, August 1 |
| » Lost to Expos (58-43), 7-5 | Stade Olympique (1-3) | 54-47 | Lost 5 |
| » W: Scott Sanderson (7-6) L: Willie Hernandez (2-1) | Third | 4 out |
| Thursday, August 2 |
| » Lost to Expos (59-43), 6-4 | Stade Olympique (1-4) | 54-48 | Lost 6 |
| » W: Dan Schatzeder (6-4) L: Bill Caudill (0-3) S: Elias Sosa (12) | Third | 5 out |
| Friday, August 3 |
| » Defeated Cardinals (52-51), 4-2 | Wrigley Field (31-21) | 55-48 | |
| » W: Rick Reuschel (10-7) L: Pete Vuckovich (10-8) S: Bruce Sutter (24) | Third | 5 out |
| Saturday, August 4 |
| » Defeated Cardinals (52-52), 8-6 | Wrigley Field (32-21) | 56-48 | Won 2 |
| » W: Mike Krukow (9-6) L: John Denny (5-9) S: Bruce Sutter (25) | Third | 4 out |
| Sunday, August 5 |
| » Defeated Cardinals (52-53), 3-2 | Wrigley Field (33-21) | 57-48 | Won 3 |
| » W: Willie Hernandez (3-1) L: Silvio Martinez (9-5) S: Bruce Sutter (26) | Third | 4½ out |
| » Lost to Cardinals (53-53), 5-4 | Wrigley Field (33-22) | 57-49 | |
| » W: Bob Forsch (5-10) L: Ken Holtzman (6-9) S: Mark Littell (6) | Third | 4½ out |
| Tuesday, August 7 |
| » Defeated Pirates (63-47), 15-2 | Wrigley Field (34-22) | 58-49 | |
| » W: Rick Reuschel (11-7) L: Jim Rooker (2-6) | Third | 3½ out |
| Wednesday, August 8 |
| » Lost to Pirates (64-47), 5-2 | Wrigley Field (34-23) | 58-50 | |
| » W: Kent Tekulve (6-6) L: Dick Tidrow (10-4) | Third | 4½ out |
| Thursday, August 9 |
| » Defeated Pirates (64-48), 11-3 | Wrigley Field (35-23) | 59-50 | |
| » W: Dennis Lamp (8-7) L: John Candelaria (10-8) | Third | 3½ out |
| Friday, August 10 |
| » Lost to Cardinals (58-53), 13-8 | Busch Stadium II (0-2) | 59-51 | |
| » W: Silvio Martinez (10-5) L: Mike Krukow (9-7) | Third | 4½ out |
| » Lost to Cardinals (59-53), 5-3 | Busch Stadium II (0-3) | 59-52 | Lost 2 |
| » W: Bob Forsch (6-10) L: Bill Caudill (0-4) S: Mark Littell (7) | Third | 4½ out |
| Saturday, August 11 |
| » Defeated Cardinals (59-54), 7-3 | Busch Stadium II (1-3) | 60-52 | |
| » W: Rick Reuschel (12-7) L: Roy Thomas (1-2) S: Bruce Sutter (27) | Third | 4½ out |
| Sunday, August 12 |
| » Defeated Cardinals (59-55), 5-3 | Busch Stadium II (2-3) | 61-52 | Won 2 |
| » W: Willie Hernandez (4-1) L: John Fulgham (4-4) S: Bruce Sutter (28) | Third | 4 out |
| Monday, August 13 |
| » Lost to Cardinals (60-55), 3-2 | Busch Stadium II (2-4) | 61-53 | |
| » W: Mark Littell (8-3) L: Willie Hernandez (4-2) | Third | 5 out |
| » Major-league debuts: Tom Herr (Cardinals) |
| Future Cub Corey Patterson is born in Atlanta, GA. |
| Tuesday, August 14 |
| » Lost to Giants (57-62), 8-2 | Wrigley Field (35-24) | 61-54 | Lost 2 |
| » W: John Curtis (8-7) L: Mike Krukow (9-8) | Third | 6 out |
| Wednesday, August 15 |
| » Defeated Giants (57-63), 6-5 | Wrigley Field (36-24) | 62-54 | |
| » W: Rick Reuschel (13-7) L: Pedro Borbon (5-5) S: Bruce Sutter (29) | Third | 6 out |
| Thursday, August 16 |
| » Defeated Giants (57-64), 14-4 | Wrigley Field (37-24) | 63-54 | Won 2 |
| » W: Lynn McGlothen (10-8) L: Bob Knepper (8-8) | Third | 6 out |
| Friday, August 17 |
| » Defeated Padres (53-70), 9-6 | Wrigley Field (38-24) | 64-54 | Won 3 |
| » W: Dick Tidrow (11-4) L: John D'Acquisto (8-11) S: Bruce Sutter (30) | Third | 5 out |
| Saturday, August 18 |
| » Defeated Padres (53-71), 3-2 | Wrigley Field (39-24) | 65-54 | Won 4 |
| » W: Dick Tidrow (12-4) L: Rollie Fingers (9-9) | Third | 4 out |
| Sunday, August 19 |
| » Defeated Padres (53-72), 3-1 | Wrigley Field (40-24) | 66-54 | Won 5 |
| » W: Rick Reuschel (14-7) L: Randy Jones (9-9) S: Bruce Sutter (31) | Third | 4 out |
| Monday, August 20 |
| » Defeated Dodgers (57-67), 2-1 | Wrigley Field (41-24) | 67-54 | Won 6 |
| » W: Lynn McGlothen (11-8) L: Rick Sutcliffe (11-9) S: Bruce Sutter (32) | Third | 4 out |
| Tuesday, August 21 |
| » Lost to Dodgers (58-67), 4-2 | Wrigley Field (41-25) | 67-55 | |
| » W: Don Sutton (11-12) L: Bill Caudill (0-5) S: Bobby Castillo (2) | Third | 4 out |
| Wednesday, August 22 |
| » Lost to Dodgers (59-67), 7-2 | Wrigley Field (41-26) | 67-56 | Lost 2 |
| » W: Charlie Hough (4-4) L: Mike Krukow (9-9) S: Bobby Castillo (3) | Third | 5 out |
| Friday, August 24 |
| » Defeated Giants (58-70), 4-1 | Candlestick Park (3-1) | 68-56 | |
| » W: Rick Reuschel (15-7) L: Vida Blue (10-11) | Third | 4 out |
| Saturday, August 25 |
| » Lost to Giants (59-70), 5-2 | Candlestick Park (3-2) | 68-57 | |
| » W: John Curtis (9-8) L: Lynn McGlothen (11-9) S: Greg Minton (1) | Third | 5 out |
| Sunday, August 26 |
| » Defeated Giants (59-71), 4-1 | Candlestick Park (4-2) | 69-57 | |
| » W: Dennis Lamp (9-7) L: John Montefusco (3-5) S: Bruce Sutter (33) | Third | 5 out |
| Monday, August 27 |
| » Lost to Padres (56-76), 5-4 | San Diego/Jack Murphy Stadium (3-1) | 69-58 | |
| » W: John D'Acquisto (9-12) L: Willie Hernandez (4-3) | Third | 5 out |
| Tuesday, August 28 |
| » Defeated Padres (56-77), 3-1 | San Diego/Jack Murphy Stadium (4-1) | 70-58 | |
| » W: Rick Reuschel (16-7) L: Randy Jones (10-10) S: Bruce Sutter (34) | Third | 5 out |
| Wednesday, August 29 |
| » Lost to Padres (57-77), 3-1 | San Diego/Jack Murphy Stadium (4-2) | 70-59 | |
| » W: Gaylord Perry (11-11) L: Lynn McGlothen (11-10) | Third | 6 out |
| Thursday, August 30 |
| » Defeated Dodgers (61-72), 4-1 | Dodger Stadium (2-1) | 71-59 | |
| » W: Dennis Lamp (10-7) L: Burt Hooton (11-10) S: Bruce Sutter (35) | Third | 5½ out |
| Friday, August 31 |
| » Lost to Dodgers (62-72), 6-4 | Dodger Stadium (2-2) | 71-60 | |
| » W: Rick Sutcliffe (13-9) L: Bill Caudill (0-6) S: Bobby Castillo (5) | Third | 6½ out |
| Saturday, September 1 |
| » Lost to Dodgers (63-72), 5-4 | Dodger Stadium (2-3) | 71-61 | Lost 2 |
| » W: Don Sutton (12-12) L: Rick Reuschel (16-8) | Third | 8 out |
| Sunday, September 2 |
| » Lost to Dodgers (64-72), 6-2 | Dodger Stadium (2-4) | 71-62 | Lost 3 |
| » W: Lerrin LaGrow (3-4) L: Bruce Sutter (4-4) | Fourth | 9 out |
| Monday, September 3 |
| » Lost to Cardinals (73-61), 2-1 | Wrigley Field (41-27) | 71-63 | Lost 4 |
| » W: John Fulgham (8-4) L: Dennis Lamp (10-8) | Fourth | 9½ out |
| Tuesday, September 4 |
| » Lost to Cardinals (74-61), 6-4 | Wrigley Field (41-28) | 71-64 | Lost 5 |
| » W: Pete Vuckovich (13-9) L: Willie Hernandez (4-4) | Fourth | 10 out |
| Wednesday, September 5 |
| » Lost to Expos (78-54), 4-3 | Wrigley Field (41-29) | 71-65 | Lost 6 |
| » W: Elias Sosa (6-7) L: Rick Reuschel (16-9) S: Dale Murray (5) | Fourth | 11 out |
| Thursday, September 6 |
| » Lost to Expos (79-54), 1-0 | Wrigley Field (41-30) | 71-66 | Lost 7 |
| » W: David Palmer (8-2) L: Lynn McGlothen (11-11) S: Woodie Fryman (8) | Fourth | 11 out |
| Friday, September 7 |
| » Defeated Phillies (70-70), 4-3 | Wrigley Field (42-30) | 72-66 | |
| » W: Dennis Lamp (11-8) L: Tug McGraw (3-3) | Fourth | 11 out |
| Saturday, September 8 |
| » Lost to Phillies (71-70), 9-8 | Wrigley Field (42-31) | 72-67 | |
| » W: Rawly Eastwick (3-4) L: Bruce Sutter (4-5) | Fourth | 11 out |
| » Major-league debuts: John Poff (Phillies) |
| Sunday, September 9 |
| » Defeated Phillies (71-71), 15-2 | Wrigley Field (43-31) | 73-67 | |
| » W: Rick Reuschel (17-9) L: Kevin Saucier (1-4) | Fourth | 11 out |
| Tuesday, September 11 |
| » Lost to Expos (82-55), 8-6 | Stade Olympique (1-5) | 73-68 | |
| » W: David Palmer (9-2) L: Lynn McGlothen (11-12) S: Elias Sosa (16) | Fourth | 12½ out |
| » Lost to Expos (83-55), 3-2 | Stade Olympique (1-6) | 73-69 | Lost 2 |
| » W: Dan Schatzeder (10-4) L: Bill Caudill (0-7) S: Elias Sosa (17) | Fourth | 12½ out |
| » Major-league debuts: Tim Raines (Expos) |
| Wednesday, September 12 |
| » Lost to Expos (84-55), 6-3 | Stade Olympique (1-7) | 73-70 | Lost 3 |
| » W: Steve Rogers (13-9) L: Bruce Sutter (4-6) | Fourth | 13½ out |
| Thursday, September 13 |
| » Lost to Expos (85-55), 4-3 | Stade Olympique (1-8) | 73-71 | Lost 4 |
| » W: Bill Atkinson (2-0) L: Rick Reuschel (17-10) | Fifth | 14 out |
| Friday, September 14 |
| » Defeated Phillies (74-72), 2-0 | Veteran's Stadium (4-3) | 74-71 | |
| » W: Bruce Sutter (5-6) L: Ron Reed (10-8) | Fourth | 13½ out |
| Saturday, September 15 |
| » Lost to Phillies (75-72), 8-1 | Veteran's Stadium (4-4) | 74-72 | |
| » W: Dan Larson (1-0) L: Lynn McGlothen (11-13) | Fifth | 14½ out |
| » Major-league debuts: George Riley (Cubs) |
| Sunday, September 16 |
| » Lost to Phillies (76-72), 4-3 | Veteran's Stadium (4-5) | 74-73 | Lost 2 |
| » W: Ron Reed (11-8) L: Dick Tidrow (12-5) | Fifth | 14½ out |
| Tuesday, September 18 |
| » Defeated Mets (56-90), 2-0 | Shea Stadium (4-4) | 75-73 | |
| » W: Rick Reuschel (18-10) L: John Pacella (0-1) S: Bruce Sutter (36) | Fifth | 14½ out |
| » Defeated Mets (56-91), 2-1 | Shea Stadium (5-4) | 76-73 | Won 2 |
| »< |